Eastern Equine Encephalitis Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Eastern Equine Encephalitis (EEEV) is an alphavirus in the family Togaviridae. They are small, enveloped virus with a genome consisting of a single strand of positive sense RNA. Disease/Infection Eastern Equine Encephalitis virus Pathogenicity Alphaviruses may be present in blood, CSF, other tissues (e.g., brain), or […]
ROHP Requirements for Medical Clearance
Who Requires Medical Clearance for Research? No Clearance Required: Researchers working on a biosafety level 1 (BSL-1) protocol who do not work with animals do not require medical clearance from ROHP. Clearance Required: Researchers working on BSL-1 protocols who do work with animals (excluding fish and amphibians) or on protocols that are BSL-2 or above […]
Prions Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Agent Prion diseases are a variety of neurodegenerative diseases which affect humans, as well as both domestic and wild animal species. In prion diseases, a cellular prion protein (PrPc) normally found in humans is transformed into a pathogenic isoform (PrPSc) upon exposure to a misfolded prion […]
Powassan virus Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent A member of the genus Flavivirus, and Flaviviridae family, is an enveloped single stranded RNA virus with two distinct lineages of similar pathogenicity. Powassan Virus is related to other Tick-Borne Encephalitis viruses and may have a similar clinical manifestation to these viruses as well as to […]
Japanese Encephalitis Virus Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Japanese encephalitis virus (JEV) is a single stranded, enveloped RNA virus which is about 40-50 nm in diameter, and belongs to the Flaviviridae family. Also referred to as JE, JEV, Japanese B Encephalitis, Arbovirus B, and Mosquito-borne encephalitis virus. Disease/Infection Japanese encephalitis may present as […]
Enteroviruses EV-D68, EV-D70, and EV-A71
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Enteroviruses EV-D68, EV-D70, and EV-A71 are viruses within the genus Enterovirus and family Picornaviridae. EV-D68 is genetically close to rhinovirus that replicates in the respiratory tract and causes respiratory disease. Since 2014, EV-D68, EV-D70 and EV-A71 have been associated with acute flaccid myelitis. Disease/Infection Acute flaccid […]
Orthobunyaviruses
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Orthobunyaviruses (over 170 species, including Batai virus, Ngari virus, Inkoo virus, Jamestown Canyon virus, Tahyna virus, Keystone virus, Bunyamwera virus) are a genus of single-stranded, tri-segmented negative-sense RNA viruses that belong to the family Peribunyaviridiae. Orthobunyaviruses are endemic to many areas of the world, including Africa, […]
Coxsackievirus B
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Coxsackieviruses are members of the Enterovirus genus (non-polio enteroviruses) in the family Picornaviridae. Enteroviruses are transient inhabitants of the gastrointestinal tract, and are stable at an acidic pH. Picornaviruses are small, ether-insensitive viruses with a RNA genome. Coxsackie viruses fall into two groups, A and B. There are 23 serotypes […]
Yellow Fever Virus Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent A member of the genus Flavivirus, and Flaviviridae family. Yellow Fever virus is a spherical, enveloped virus of 40 to 50 nm in diameter, and has a single-stranded, positive- sense RNA genome. Disease/Infection Classic Yellow Fever is characterized by three clinical illness stages: infection, remission, and […]
Paramyxoviruses (Hendra and Nipah Virus)
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Hendra and Nipah viruses belong to the Henipavirus genus within the family of Paramyxoviridae and are of zoonotic origin. The natural reservoir of these viruses are pteropid fruit bats. Hendra virus is endemic in Australia. Since 1994, there were 7 human cases of Hendra virus infection. […]