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ROHP Requirements for Medical Clearance

Last updated on June 15, 2024 4 min read Research Occupational Health Program - ROHP Requirements for Medical Clearance

Where to Complete Your Paperwork

Employees should complete questionnaires and upload immunization documents through their Occupational Health Connect Portal (preferred). If you do not see the questionnaires in your portal, please contact ROHP.

If you are a new hire or student, or an employee who does not see the questionnaires in your portal, you may complete through the web using the links in this page.

Who Requires Medical Clearance for Research?

No Clearance Required: Researchers working on a biosafety level 1 (BSL-1) protocol who do not work with animals do not require medical clearance from ROHP.

Clearance Required: Researchers working on BSL-1 protocols who do work with animals (excluding fish and amphibians) or on protocols that are BSL-2 or above still require ROHP clearance. Please read on to learn more.

Should a researcher’s work change, either to include animals or to begin work in a BSL-2 lab, they should submit a new Job Risk Assessment and Health Questionnaire to ROHP, as described below.

Required Initially and Annually

The following requirements apply to researchers on BSL-2 or above protocols, or on BSL-1 protocols working with animals (excluding fish and amphibians), who are working with human specimens, on an IACUC protocol with animals, on an IBC protocol, or who require access to research laboratories or animal care facilities (i.e., working, visiting, cleaning, or maintenance) where hazardous materials may be used:

Your work environment as indicated in the Job Risk Assessment form will determine screenings required in order to obtain medical clearance.


Additional Screenings, by Work Environment

Once you have completed the Job Risk Assessment and the Health Questionnaire above, please select the header below that best describe your work environment for a list of further requirements.

The list below is to be used as a guide. Additional screenings may be required after review of the Job Risk Assessment.

Work with human subjects (on an IBC protocol)

  • Initial 2-step Tuberculosis skin test or blood test if greater than 1 year since your last TB test. TB symptom screening is required annually thereafter. If previous history of a positive TB test, please submit documentation including written chest x-ray report for review. TB symptom screen annually thereafter.
  • Proof of two Measles, Mumps, and Rubella (MMR) vaccinations OR positive MMR Titers
  • Proof of two Varicella vaccines OR positive varicella titer
  • *Proof of three Hepatitis B vaccination (Engerix) or two doses of (Heplisav)
  • OSHA Respirator Health Questionnaire
  • Tdap vaccination
  • BU COVID-19 Policies
  • Yearly Flu vaccine is strongly recommended

Work with human cells, tissue, blood, or human cell lines or health care provider working directly with human subjects

Patient or human subject contact:

All staff and researchers with patient contact are required to provide written documentation of having Hepatitis B vaccination series (dates must include month/day/year and be signed by healthcare provider) or read the Centers for Disease Control and Prevention’s Vaccine Information Statement and sign the Hepatitis B vaccination declination form to decline the vaccine.

  1. If you have written documentation of your hepatitis B vaccine, you MUST also submit evidence of a quantitative, hepatitis B titer that was drawn at least 4-6 weeks or longer after the date of your last hepatitis B vaccine dose (or if you have had booster doses, the date of the last booster dose).
    1. Please note, if your hepatitis B titer is negative (<10 mIU/mL) you should receive a booster dose of the vaccine and have your titer re-drawn 4-6 weeks later.
    2. If you are considered a “non-responder” (negative titer after 6 doses) Hepatitis B surface antigen testing will be offered. The researcher will be offered the 2 dose Heplisav Vaccine which has greater response rate.
  2. If you are unable to locate your hepatitis B vaccination records and are declining the vaccination, a HBsAb titer may be obtained.

Working with human blood, cells or tissue:

Researchers working with human blood, tissues and cells are asked to provide written documentation of Hepatitis B vaccination.  If unable to provide documentation, the Hepatitis B vaccine series will be offered.  If researchers decline the Hepatitis B vaccine, they will be asked to submit a signed a Hepatitis B Vaccine Declination Form.

A Hepatitis B quantitative titer is required. A positive Hep B titer is acceptable documentation for clearance.

Work with non-human primates or accessing space

  • Initial 2-step TB skin test or blood test if greater than 1 year since last TB test. TB symptom screening and testing are required annually thereafter. If previous history of positive TB test, please submit documentation including written chest x-ray report for review. TB screening test annually thereafter.
  • Proof of two Measles, Mumps, and Rubella (MMR) vaccinations OR positive measles titer
  • Annual flu vaccine is strongly recommended

Tuberculosis screening requirements, please refer to this link and  TB Symptom Screen form.

Work with animals and have animal allergies

Work requiring the use of a respirator (for example N95, PAPR, half or full faced or supplied air respirator)

Work in the MRI environment

NEIDL

  • Participation in mental/behavioral health and urine drug screening program
  • Screenings determined by biosafety level and work environment

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