References – K
Ka SM, Cheng CW, Shui HA, Wu WM, Chang DM, Lin YC and Chen A (2007) Mesangial cells of lupus-prone mice are sensitive to chemokine production. Arthritis Research & Therapy 9 R67
Ka SM, Huang XR, Lan HY, Tsai PY, Yang SM, Shui HA and Chen A (2007) Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. Journal of the American Society of Nephrology 18 1777-1188
Kaarniranta K, Elo MA, Sironen RK, Karjalainen HM, Helminen HJ and Lammi MJ (2002) Stress responses of mammalian cells to high hydrostatic pressure. Biorheology 40 87-92
Kaarniranta K, Ryhanen T, Karjalainen HM, Lammi MJ, Suuronen T, Huhtala A, Kontkanen M, Terasvirta M, Uusitalo H and Salminen A (2005) Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells. Neuroscience Letters 382 185-190
Kabanov A, Zhu J and Alakhov V (2005) Pluronic block copolymers for gene delivery. Advances in Genetics 53 231-261
Kabashima K, Honda T, Nunokawa Y and Miyachi Y (2004) A new NF-kB inhibitor attenuates a T(H)1 type immune response in a murine model. FEBS Letters 578 36-40
Kabay B, Teke Z, Aytekin FO, Yenisey C, Bir F, Sacar M, Erdem E and Ozden A (2007) Pyrrolidine dithiocarbamate reduces lung injury caused by mesenteric ischemia/reperfusion in a rat model. World Journal of Surgery in press
Kabe Y, Ando K, Hirao S, Yoshida M and Handa H (2005) Redox regulation of NF-kB activation: distinct redox regulation between the cytoplasm and the nucleus.Antioxidants and Redox Signaling 7 395-403
Kabouridis PS, Hasan M, Newson J, Gilroy DW and Lawrence T (2002) Inhibition of NF-kB activity by a membrane-transducing mutant of IkBa. Journal of Immunology 169 2587-2593
Kabrun N, Bumstead N, Hayman MJ and Enrietto PJ (1990) Characterization of a novel promoter insertion in the c-rel locus. Molecular and Cellular Biology 10 4788-4794
Kabrun N and Enrietto PJ (1994) The Rel family of proteins in oncogenesis and differentiation. Seminars in Cancer Biology 5 103-112
Kabrun N, Hodgson JW, Doemer M, Mak G, Franza BR and Enrietto PJ (1991) Interaction of the v-rel protein with an NF-kB DNA binding site. Proceedings of the National Academy of Sciences USA 88 1783-1787
Kabu K, Yamasaki S, Kamimura D, Ito Y, Hasegawa A, Sato E, Kitamura H, Nishida K and Hirano T (2006) Zinc is required for Fc{epsilon}RI-mediated mast cell activation.Journal of Immunology 177 1296-1305
Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurrey KR, Murase N and Billiar TR (2007) Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Transplantation 84 1279-1287
Kadhim HS, Al-Jeboori TI and Tawfik MS (2006) Possible role of nuclear factor kappaB detected by in situ hybridization in the pathogenesis of transitional cell carcinoma of the bladder.
Journal Medical Libanais 54 196-199
Kadoya H, Nagano-Fujii M, Deng L, Nakazono N and Hotta H (2005) Nonstructural proteins 4A and 4B of hepatitis C virus transactivate the interleukin 8 promoter.Microbiolgoy and Immunology 49 265-273
Karoury RM, Hernandez JM, Lasky JA, Toscano Jr WA and Friedman M (2007) Activation of transcription factor IL-6 (NF-IL-6) and nuclear factor-kB (NF-kB) by lipid ozonation products is crucial to interleukin-8 gene expression in human airway epithelial cells. Environmental Toxicology 22 159-168
Kafoury RM and Kelley J (2005) Ozone enhances diesel exhaust particles (DEP)-induced interleukin-8 (IL-8) gene expression in human airway epithelial cells through activation of nuclear factors- kB (NF-kB) and IL-6 (NF-IL6). International Journal of Environmental Research and Public Health 2 403-410
Kafoury RM and Madden MC (2005) Diesel exhaust particles induce the over expression of tumor necrosis factor-a (TNF-a) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kB (NF-kB). International Journal of Environmental Research and Public Health 2 107-113
Kagami S, Saeki H, Komine M, Kakinuma T, Nakamura K, Tsunemi Y, Sasaki K, Asashina A and Tamaki K (2006) CCL28 production in HaCaT cells was mediated by different signal pathways from CCL27. Experimental Dermatology 15 95-100
Kagan-Ponomarev MIa (2004) Clinical value of some factors of gene transcription in heart diseases [Article in Russian]. Kardiologiia 44 66-70
Kagemann G, Henrich B, Kuhn M, Kleinert H and Schnorr O (2005) Impact of Mycoplasma hyorhinis infection on l-arginine metabolism: differential regulation of the human and murine iNOS gene. Biology and Chemistry 386 1055-1063
Kagemann G, Sies H and Schnorr O (2007) Limited availability of L: -arginine increases DNA-binding activity of NF-kB and contributes to regulation of iNOS expression. Journal of Molecular Medicine in press
Kagoshima M, Ito K, Cosio B and Adcock IM (2003) Glucocorticoid suppression of nuclear factor-kB: a role for histone modifications. Biochemical Society Transactions 31 60-65
Kagoshima M, Cosio B and Adcock IM (2003) How signaling pathways interact with gene transcription. Monaldi Archives of Chest Disease 59 30-37
Kahlenberg JM, Lundberg KC, Kertesy SB, Qu Y and Dubyak GR (2005) Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kB-driven protein synthesis. Journal of Immunology 175 7611-7622
Kahn AU and Wilson T (1995) Reactive oxygen species as cellular messengers. Current Biology 2 437-445
Kahn-Perlès B, Lipcey C, Lécine P, Olive D and Imbert J (1997) Temporal and subunit-specific modulations of the Rel/NF-kB transcription factors through CD28 costimulation. Journal of Biological Chemistry 272 21774-21783
Kaibori M, Okumura T, Ito S, Oda M, Inoue T and Kamiyama Y (1999) Inhibition of iNOS induction by FK506, but not by cyclosporine, in rat hepatocytes. Transplantation Proceedings 31 804-805
Kaibori M, Sakitani K, Oda M, Kamiyama Y, Masu Y, Nishizawa M, Ito S and Okumura T (1999) Immunosuppressant FK506 inhibits inducible nitric oxide synthase gene expression at a step of NF-kB activation in rat hepatocytes. Journal of Hepatology 30 1138-1145
Kaibori M, Yanagida H, Nakanishi H, Ozaki T, Yoshida H, Matsui K, Hijakawa T, Kamiyama Y and Okumura T (2006) Hepatocyte growth factor stimulates the induction of cytokine-induced neutrophil chemoattractant through the activation of NF-kB in rat hepatocytes. Journal of Surgical Research 130 88-93
Kaibori M, Yanagida H, Nakanishi H, Yokoigawa N, Kwon AH, Okumura T and Kamiyama Y (2004) Effect of hepatocyte growth factor on induction of cytokine-induced neutrophil chemoattractant in rat hepatocytes. Transplantation Proceedings 36 1977-1979
Kaileh M, Vanden Berghe W, Heyerick A, Horion J, Piette J, Libert C, De Keukeleire D, Essawi T and Haegeman G (2007) Withaferin A strongly elicits IKKbeta hyperphosphorylation, concomitant with potent inhibition of its kinase activity.Journal of Biological Chemistry 282 4253-4264
Kairisalo M, Kornonen L, Blomgren K and Lindholm D (2007) X-linked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kB activation.Biochemical and Biophysical Research Communications 364 138-144
Kaiser GC, Yan F and Polk DB (1999) Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kB activation in mouse colonocytes. Gastroenterology 116 602-609
Kaiser P, Rothwell L, Goodchild M and Bumstead N (2004) The chicken proinflammatory cytokines interleukin-1beta and interleukin-6: differences in gene structure and genetic location compared with their mammalian orthologues. Animal Genetics 35 169-175
Kaiser S and Toborek M (2003) High-efficiency transfection of human endothelial cells mediated by cationic lipids. Journal of Neurochemistry 85 22
Kaiser WJ and Offermann MK (2005) Apoptosis induced by the Toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif. Journal of Immunology 174 4942-4952
Kaisho T, Takeda K, Tsujimura T, Kawai T, Nomura F, Terada N and Akira S (2001) IkB kinase a is essential for mature B cell development and function. Journal of Experimental Medicine 193 417-426
Kaizu T, Nakao A, Tsung A, Toyokawa H, Sahai R, Geller DA and Murase N (2005) Carbon monoxide inhalation ameliorates cold ischemia/reperfusion injury after rat liver transplantation. Surgery 138 229-235
Kajiguchi T, Yamamoto K, Iida S, Ueda R, Emi N andNaoe T (2006) Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines. Cancer Science 97 540-545
Kajino S, Suganuma M, Teranishi F, Takahashi N, Tetsuka T, Ohara H, Itoh M and Okamoto T (2000) Evidence that de novo protein synthesis is dispensable for anti-apoptotic effects of NF-kB. Oncogene 19 2233-2239
Kajita K, Mune T, Kanoh Y, Natsume Y, Ishizawa M, Kawai Y, Yasuda K, Sugiyama C and Ishizuka T (2004) TNFa reduces the expression of peroxisome proliferator-activated receptor gamma (PPARg) via the production of ceramide and activation of atypical PKC. Diabetes Research and Clinical Practice 66 S79-S83
Kajiura F, Sun S, Nomura T, Izumi K, Ueno T, Bando Y, Kuroda N, Han H, Li Y, Matsushima A, Takahama Y, Sakaguchi S, Mitani T and Matsumoto M (2004) NF-kB-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. Journal of Immunology 172 2067-2075
Kakegawa T, Hayakawa A, Itaya N, Saito H and Kobayashi H (2001) Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2 [Article in Japanese]. Japanese Journal of Antibiotics 54 Suppl A 93-95
Kako K, Nishikawa M, Yoshida H and Takakura Y (2007) Effects of inflammatory response on in vivo transgene expression by plasmid DNA in mice. Journal of Pharmacological Science in press
Kaku H, Horikawa K, Obata Y, Kato I, Okamoto H, Sakaguchi N, Gerondakis S and Takatsu K (2002) NF-kB is required for CD38-mediated induction of C(gamma)1 germline transcripts in murine B lymphocytes. International Immunology 14 1055-1064
Kakeya H, Onose R, Koshino H, Yoshida A, Kobayashi K, Kageyama S and Osada H (2002) Epoxyquinol A, a highly functionalized pentaketide dimer with antiangiogenic activity isolated from fungal metabolites. Journal of the American Chemical Society 124 3496-3497
Kakisis JD, Liapis CD and Sumpio BE (2004) Effects of cyclic strain on vascular cells. Endothelium 11 17-28
Kalaitzidis D, Davis RE, Rosenwald A, Staudt LM and Gilmore TD (2002) The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kB signal transduction pathway. Oncogene 21 8759-8768
Kalaitzidis D and Gilmore TD (2001) Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8. Genes, Chromosomes & Cancer 34 129-135
Kalaitzidis D and Gilmore TD (2005) Transcription factor cross-talk: estrogen receptor and NF-kB. Trends in Endocrinology and Metabolism 16 46-52
Kalaitzidis D, Ok J, Sulak L, Starczynowski DT and Gilmore TD (2004) Characterization of a human REL-estrogen receptor fusion protein with a reverse conditional transforming activity in chicken spleen cells. Oncogene 23 7580-7587
Kalariya NM, Ramana KV, Srivastava SK and van Kuijk FJ (2007) Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells. Experimental Eye Research in press
Kalayarasan S, Sriram N and Sudharndiran G (2008) Diallyl sulfide attenuates bleomycin-induced pulmonary fibrosis: Critical role of iNOS, NF-kB, TNF-a and IL-1b. Life Sciences in press
Kalden DH, Scholzen T, Brzoska T and Luger TA (1999) Mechanisms of the antiinflammatory effects of alpha-MSH. Role of transcription factor NF-kB and adhesion molecule expression. Annals of the New York Academy of Sciences 885 254-261
Kaler P, Sasazuki T, Shirazawa S, Augenlicht L and Klampfer L (2008) HDAC2 deficiency sensitizes colon cancer cells to TNFa-induced apoptosis through inhibition of NF-kB activity. Experimental Cell Research in press
Kaliman P, Canicio J, Testar X, Palacin M and Zorzano A (1999) Insulin-like growth factor-II, phosphatidylinositol 3-kinase, nuclear factor-kB and inducible nitric-oxide synthase define a common myogenic signaling pathway. Journal of Biological Chemistry 274 17437-17444
Kalinowski M, Viehofer K, Hamann C, Barry JJ, Kleb B, Klose KJ, Wagner HJ and Alfke H (2005) Local administration of NF-kB decoy oligonucleotides to prevent restenosis after balloon angioplasty: an experimental study in New Zealand white rabbits.Cardiovascular and Interventional Radiology 28 331-337
Kalli K, Huntoon C, Bell M and McKean DJ (1998) Mechanism responsible for T-cell antigen receptor- and CD28- or Interleukin 1 (IL-1) receptor-initiated regulation of IL-2 gene expression by NF-kB. Molecular and Cellular Biology 18 3140-3148
Kalman J, Kudchodkar BJ, Krishnamoorthy R, Dory L, Lacko AG and Agarwal N (2001) High cholesterol diet down regulates the activity of activator protein- 1 but not nuclear factor-kappaB in rabbit brain. Life Sciences 68 1495-1503
Kalogeris T, Gray L, Laroux, FS, Cockrell A, Fuseler J, Conner EM, Brand S and Grisham MB (1999) Selective proteasome inhibitors as anti-inflammatory agents. Expert Opinion in Investigative Drugs 8 1397-1407
Kalogeris TJ, Kevil CG, Laroux FS, Coe LL, Phifer TJ and Alexander JS (1999) Differential monocyte adhesion and adhesion molecule expression in venous and arterial endothelial cells. American Journal of Physiology 276 L9-L19
Kalpana S, Dhananjaay S, Anju B, Lilly G and Sai Ram M (2008) Cobalt chloride attenuates hypobaric hypoxia induced vascular leakage in rat brain: molecular mechanisms of action of cobalt chloride. Toxicology and Applied Pharmacology in press
Kalra D, Baumgarten G, Dibbs Z, Seta Y, Sivasubramanian N and Mann DL (2000) Nitric oxide provokes tumor necrosis factor-alpha expression in adult feline myocardium through a cGMP-dependent pathway. Circulation 102 1302-1307
Kalra N, Bhui K, Roy P, Srivastava S, George J, Prasad S and Shukla Y (2007) Regulation of p53, nuclear factor kB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin. Toxicology and Applied Pharmacology in press
Kalra N, Seth K, Prasad S, Singh M, Pant AB and Shukla Y (2007) Theaflavins induced apoptosis of LNCaP cells is mediated through induction of p53, down-regulation of NF-kB and mitogen-activated protein kinases pathways. Life Sciences 80 2137-2140
Kaltschmidt B and Kaltschmidt C (2000) Constitutive NF-kB activity is modulated via neuron-astroglia interaction. Experimental Brain Research 130 100-104
Kaltschmidt B, Baeuerle PA and Kaltschmidt C (1993) Potential involvement of the transcription factor NF-kB in neurological disorders. Molecular Aspects of Medicine 14 171-190
Kaltschmidt B, Deller T, Frotscher M and Kaltschmidt C (2000) Ultrastructural localization of activated NF-kB in granule cells of the rat fascia dentata. Neuroreport 11 839-844
Kaltschmidt B, Heinrich M and Kaltschmidt C (2002) Stimulus-dependent activation of NF-kB specifies apoptosis or neuroprotection in cerebellar granule cells. Neuromolecular Medicine 2 299-309
Kaltschmidt B, Kaltschmidt C, Hehner SP, Dröge W and Schmitz ML (1999) Repression of NF-kB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators. Oncogene 18 3213-3225
Kaltschmidt B, Linker RA, Deng J, Kaltschmidt C (2002) Cyclooxygenase-2 is a neuronal target gene of NF-kB. BMC Molecular Biology 3 16
Kaltschmidt B, Ndiaye D, Korte M, Pothion S, Arbibe L, Prullage M, Pfeiffer J, Lindecke A, Staiger V, Israel A, Kaltschmidt and Memet S (2006) NF-kB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling. Molecular and Cellular Biology 26 2936-2946
Kaltschmidt B, Uherek M, Wellmann H, Volk B and Kaltschmidt C (1999) Inhibition of NF-kB potentiates amyloid b-mediated neuronal apoptosis. Proceedings of the National Academy of Sciences USA 96 9409-9414
Kaltschmidt B, Widera D and Kaltschmidt C (2005) Signaling via NF-kB in the nervous system. Biochimica et Biophysica Acta 1745 287-299
Kaltschmidt C, Kaltschmidt B and Baeuerle PA (1993) Brain synapses contain inducible forms of the transcription factor NF-kB. Mechanisms of Development 43 135-147
Kaltschmidt C, Kaltschmidt B and Baeuerle PA (1995) Stimulation of ionotropic glutamate receptors activates transcription factor NF-kB in primary neurons. Proceedings of the National Academy of Sciences USA 92 9618-9622
Kaltschmidt C, Kaltschmidt B, Henkel T, Stockinger H and Baeuerle PA (1995) Selective recognition of the activated form of transcription factor NF-kB by a monoclonal antibody. Biological Chemistry Hoppe-Seyler 376 9-16
Kaltschmidt C, Kaltschmidt B, Lannes-Vieira J, Kreuzberg G, Wekerle H, Baeuerle PA and Gehrmann J (1994) Activation of transcription factor NF-kB in microglia during experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 55 99-106
Kaltschmidt C, Kaltschmidt B, Neumann H, Wekerle H and Baeuerle PA (1994) Constitutive NF-kB activity in neurons. Molecular and Cellular Biology 14 3981-3992
Kaltschmidt C, Kaltschmidt B, Volk B and Baeuerle PA (1997) Transcription factor NF-kB is activated in primary neurons by amyloid bA4 and in neurons surrounding early plaques from Alzheimer disease patients. Proceedings of the National Academy of Sciences USA 94 2642-2647
Kalvakolanu DVR and Sen GC (1993) Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-kB in mouse embryonal carcinoma cells. Proceedings of the National Academy of Sciences USA 90 3167-3171
Kalyanasundaram A, Elmore JR, Manazer JR, Golden A, Franklin DP, Galt SW, Zakhary EM and Carey DJ (2006) Simvastatin suppresses experimental aortic aneurysm expansion. Journal of Vascular Surgery 43 117-117
Kam AY, Liu AM and Wong YH (2007) Formyl peptide-receptor like-1 requires lipid raft and extracellular signal-regulated protein kinase to activate inhibitor-kappaB kinase in human U87 astrocytoma cells. Journal of Neurochemistry 103 1553-1566
Kamachi F, Yanai M, Ban HS, Ishihara K, Hong J, Ohuchi K and Hirasawa N (2007) Involvement of Na(+)/H(+) exchangers in induction of cyclooxygenase-2 by vacuolar-type (H(+))-ATPase inhibitors in RAW 264 cells. FEBS Letters 581 4633-4638
Kamada N, Maeda K, Inoue N, Hisamatsu T, Okamoto S, Hong KS, Yamada T, Watanabe N, Tsuchimoto K, Ogata H and Hibi T (2007) Non-pathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells. Infection and Immunity in press
Kamat AM, Sethi G and Aggarwal BB (2007) Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kB and nuclear factor-kB-regulated gene products in IFN-a-sensitive and IFN-a-resistant human bladder cancer cells. Molecular Cancer Therapeutics 6 1022-1030
Kamata H, Honda SI, Maeda S, Chang L, Hirata H and Karin M (2005) Reactive oxygen species promote TNFa-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120 649-661
Kamata H, Manabe T, Kakuta J, Oka S and Hirata H (2002) Multiple redox regulation of the cellular signaling system linked to AP-1 and NFkB: effects of N-acetylcysteine and H2O2 on the receptor tyrosine kinases, the MAP kinase cascade, and IkB kinases. Annals of the New York Academy of Sciences 973 419-422
Kamata H, Manabe T, Oka S, Kamata K and Hirata H (2002) Hydrogen peroxide activates IkB kinases through phosphorylation of serine residues in the activation loops. FEBS Letters 519 231-237
Kamata K, Okamoto S, Oka S, Kamata H, Yagisawa H and Hirata H (2001) Cycloprodigiosin hydrocloride suppresses tumor necrosis factor (TNF) alpha-induced transcriptional activation by NF-kB. FEBS Letters 507 74-80
Kamens J and Brent R (1991) A yeast transcription assay defines distinct Rel and Dorsal DNA recognition sequences. New Biologist 3 1005-1013
Kamens J, Richardson P, Mosialos G, Brent R and Gilmore T (1990) Oncogenic transformation by vRel requires an amino-terminal activation domain. Molecular and Cellular Biology 10 2840-2847
Kamer S, Ren Q and Dicker AP (2008) Differential radiation sensitization of human cervical cancer cell lines by the proteasome inhibitor velcade (bortezomib, PS-341). Archives of Gynecology and Obstetrics in press
Kameyama N, Arisawa S, Ueyama J, Kagota S, Shinozuka K, Hattori A, Tatsumi Y, Hayashi H, Takagi K and Wakusawa S (2008) Increase in P-glycoprotein accompanied by activation of protein kinase Calpha and NF-kB p65 in the livers of rats with streptozotocin-induced diabetes. Biocimica et Biophysica Acta in press
Kamiyama H, Usui T, Sakurai H, Shoji M, Hayashi Y, Kakeya N and Osada H (2008) Epoxyquinol B, a naturally occurring pentaketide dimer, inhibits NF-kB signaling by crosslinking TAK1. Bioscience Biotechnology and Biochemistry in press
Kammanadiminti SJ and Chadee K (2006) Suppression of NF-kB activation by Entameba histolytica in intestinal epithelial cells is mediated by heat shock protein 27.Journal of Biological Chemistry 281 26069-26080
Kammanadiminti SJ, Dey I and Chadee K (2007) Induction of monocyte chemotactic protein-1 in colonic epithelial cells by Entamoeba histolytica is mediated via PI3 kinase/p65 pathway. Infection and Immunity 75 1765-1770
Kammanadiminti SJ, Mann BJ, Dutil L and Chadee K (2003) Regulation of Toll-like receptor-2 expression by the Gal-lectin of Entamoeba histolytica. FASEB Journal 18 155-157
Kamon J, Yamauchi T, Muto S, Takekawa S, Ito Y, Hada Y, Ogawa W, Itai A, Kasuga M, Tobe K and Kadowaki T (2004) A novel IKKbeta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance. Biochemical and Biophysical Research Communications 323 242-248
Kameoka M, Ota K, Tetsuka T, Tanaka Y, Itaya A, Okamoto T and Yoshihara K (2000) Evidence for regulation of NF-kB by poly(ADP-ribose) polymerase. Biochemical Journal 346 641-649
Kameoka M, Tanaka Y, Ota K, Itaya A and Yoshihara K (1999) Poly (ADP-ribose) polymerase is involved in PMA-induced activation of HIV-1 in U1 cells by modulating the LTR function. Biochemical and Biophysical Research Communications 262 285-289
Kamezaki K, Shimoda K, Numata A, Matsuda T, Nakayama KI and Harada M (2004) The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals. International Immunology 16 1173-1179
Kamijo S, Nakajima A, Ikeda K, Aoki K, Ohya K, Akiba H, Yagita H and Okumura K (2006) Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody. Biochemical and Biophysical Research Communications in press
Kamine J and Chinnadurai G (1992) Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral tat protein and cellular transcription factor Sp1. Journal of Virology 66 3932-3936
Kamiya S, Nakamura C, Fukawa T, Ono K, Ohwaki T, Yoshimoto T and Wada S (2007) Effects of IL-23 and IL-27 on osteoblasts and osteoclasts: inhibitory effects on osteoclast differentiation.
Journal of Bone and Mineral Metabolism 25 277-285
Kammanadiminti SJ and Chadee K (2006) Suppression of NF-kB activation by Entamoeba hisotlytica in intestinal epithelial cells is mediated by heat shock protein 27. Journal of Biological Chemistry 281 26069-26080
Kammanadiminti SJ and Chadee K (2007) Induction of monocyte chemotactic protein-1 in colonic epithelial cells by Entamoeba histolytica is mediated via PI3 kinase/P65 pathway. Infection and Immunity in press
Kammanadiminti SJ, Mann BJ, Dutil L and Chadee K (2003) Regulation of Toll-like receptor-2 expression by the Gal-lectin of Entamoeba histolytica. FASEB Journal 18 155-157
Kamaohara H, Takahashi M, Ishiko T, Ogawa M and Baba H (2007) Induction of interleukin-8 (CXCL-8) by tumor necrosis factor-a and leukemia inhibitory factor in pancreatic carcinoma cells: impact of CXCL-8 as an autocrine growth factor.International Journal of Oncology 31 627-632
Kamolmatyakul S, Chen W, Yang S, Abe Y, Moroi R, Ashique AM and Li YP (2004) IL-1{alpha} Stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kB pathway. Journal of Dental Research 83 791-796
Kampf C and Roomans GM (2001) Effects of hypochlorite on cultured respiratory epithelial cells. Free Radical Research 34 499-511
Kamthong PJ and Wu M (2001) Inhibitor of nuclear factor-kB induction by cAMP antagonizes interleukin-1-induced human macrophage-colony-stimulating-factor expression. Biochemical Journal 356 525-530
Kan H, Xie Z and Finkel MS (1999) TNF-a enhances cardiac myocyte NO production through MAP kinase-mediated NF-kB activation. American Journal of Physiology 277 H1641-H1646
Kanai K, Asano K, Hisamitsu T and Suzaki H (2004) Suppression of matrix metalloproteinase production from nasal fibroblasts by macrolide antibiotics in vitro. European Repiratory Journal 23 671-678
Kanai KI, Asano K, Hisamitsu T and Suzaki H (2004) Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro. Mediators of Inflammation 13 313-319
Kanai KI, Asano K, Watanabe S, Kyo Y and Suzaki H (2006) Epinastine hydrochloride antagonism against interleukin-4-mediated T cell cytokine imbalance in vitro. International Archives of Allergy and Immunology 140 43-52
Kanai M, Konda Y, Nakajima T, Izumi Y, Takeuchi T and Chiba T (2001) TGF-a inhibits apoptosis of murine gastric pit cells through an NF-kB-dependent pathway. Gastroenterology 121 56-67
Kanakaraj P, Migone TS, Nardelli B, Ullrich S, Li Y, Olsen HS, Salcedo TW, Kaufman T, Cochrane E, Gan Y, Hilbert DM and Giri J (2001) BLyS bind to B cells with high affinity and induces activation of the transcription factors NF-kB and Elf1. Cytokine 13 25-31
Kanakaraj P, Ngo K, Wu Y, Angulo A, Ghazal P, Harris CA, Siekierka JJ, Peterson PA and Fung-Leung WP (1999) Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice. Journal of Experimental Medicine 189 1129-1138
Kanakiriya SK, Croatt AJ, Haggard JJ, Ingelfinger JR, Tang SS, Alam J and Nath KA (2003) Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms. American Journal of Physiology: Renal Physiology 284 F546-F554
Kanamaru C, Yasuda H, Takeda M, Ueda N, Suzuki J, Tsuchida T, Mashima H, Ohnishi H and Fujita T (2001) Smad7 is induced by norepinephrine and protects rat hepatocytes from activin A-induced growth inhibition. Journal of Biological Chemistry 276 45636-45641
Kanamaru F, Youngnak P, Hashiguchi M, Nishioka T, Takahashi T, Sakaguchi S, Ishikawa I and Azuma M (2004) Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells. Journal of Immunology 172 7306-7314
Kanamori M, Kai C, Hayashizaki Y and Suzuki H (2002) NF-kB activator Act1 associates with IL-1/Toll pathway adaptor molecule TRAF6. FEBS Letters 532 241-246
Kanatani M, Sugimoto T, Kano J, Kanzawa M and Chihara K (2003) Effect of high phosphate concentration on osteoclast differentiation as well as bone-resorbing activity. Journal of Cellular Physiology 196 180-189
Kanatani M, Sugimoto T, Sowa H, Kobayashi T, Kanzawa M and Chihara K (2004) Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL-RANK interaction. Journal of Cellular Physiology 201 17-25
Kanauchi O, Andoh A, Iwanaga T, Fujiyama Y, Mitsuyama K, Toyonaga A and Bamba T (1999) Germinated barley foodstuffs attenuate colonic mucosal damage and mucosal nuclear factor kappa B activity in a spontaneous colitis model. Journal of Gastroenterology and Hepatology 14 1173-1179
Kanayama A, Inoue JI, Konishi YS, Shimizu M and Miyamoto Y (2002) Oxidation of Ikappa Balpha at Methionine 45 is one cause of taurine chloramine-induced inhibition of NF kB activation. Journal of Biological Chemistry 277 24049-24056
Kanayama A and Miyamoto Y (2007) Apoptosis triggered by phagocytosis-related oxidative stress through FLIPS down-regulation and JNK activation. Journal ofLeukocyte Biology 82 1344-1352
Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, Chiu YH, Deng L and Chen ZJ (2004) TAB2 and TAB3 activate the NF-kB pathway through binding to polyubiquitin chains. Molecular Cell 15 535-548
Kanayama S, Yamada Y, Onogi A, Shigetomi H, Ueda S, Tsuji Y, Haruta S, Kawaguchi R, Yoshida S, Sakata M, Sado T, Kitanaka T, Oi H, Yagyu T and Kobayahsi H (2007) Bikunin suppresses expression of pro-inflammatory cytokines induced by lipopolysaccharide in neutrophils. Journal of Endotoxin Research 13 369-376
Kanazawa K, Azuma Y, Nakano H and Kudo A (2003) TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesis. Journal of Bone and Mineral Research 18 443-450
Kanazawa K and Kudo A (2005) TRAF2 is essential for TNF-a-induced osteoclastogenesis. Journal of Bone and Mineral Research 20 840-847
Kanazawa N (2007) Clinical features of Blau syndrome and early-onset sarcoidosis and associating CARD15/NOD2 gene mutations. Nihon Rinsho Meneki Gakkai Kaishi 30 123-132
Kanazawa N, Okafuji I, Kambe N, Nishikomori R, Nakata-Hizume M, Nagai S, Fuji A, Yuasa T, Manki A, Sakurai Y, Nakajima M, Kobayashi H, Fujiwara I, Tsutsumi H, Utani A, Nishigori C, Heike T, Nakahata T and Miyachi Y (2005) Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kB activation: common genetic etiology with Blau syndrome. Blood 105 1195-1197
Kanazawa T, Takashima Y, Hirayama S, and Okada H (2008) Effects of menstrual cycle on gene transfection through mouse vagina for DNA vaccine. International Journal of Pharmacology in press
Kanda K, Hu HM, Zhang L, Grandchamps J and Boxer LM (2000) NF-kB activity is required for the deregulation of c-myc expression by the immunoglobulin heavy chain enhancer. Journal of Biological Chemistry 41 32388-32346
Kanda N, Koike S and Watanabe S (2005) IL-17 suppresses TNF-a-induced CCL27 production through induction of COX-2 in human keratinocytes. Journal of Allergy and Clinical Immunology 116 1144-1150
Kanda N, Mitsui H and Watanabe S (2004) Prostaglandin E2 suppresses CCL27 production through EP2 and EP3 receptors in human keratinocytes. Journal of Allergy and Clinical Immunology 114 1403-1409
Kanda N, Shimizu T, Tada Y and Watanabe S (2007) IL-18 enhances IFN-g-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. European Journal of Immunology 37 338-350
Kanda N and Watanabe S (2004) Histamine enhances the production of granulocyte-macrophage colony-stimulating factor via protein kinase Calpha and extracellular signal-regulated kinase in human keratinocytes. Journal of Investigative Dermatology 122 863-872
Kanda N and Watanabe S (2006) Suppressive effects of antimycotics on tumor necrosis factor-alpha-induced CCL27, CCL2, and CCL5 production in human keratinocytes.Biochemical Pharmacology 72 463-473
Kanda N and Watanabe S (2007) Prolactin enhances interferon-g-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. Endocrinology 148 2317-2325
Kanda N, and Watanabe S (2007) Leukotriene B(4) enhances tumour necrosis factor-alpha-induced CCL27 production in human keratinocytes. Clinical and Experimental Allergy 37 1074-1082
Kanda N and Watanabe S (2007) Histamine enhances the production of human beta-defensin-2 in human keratinocytes. American Journal of Physiology: Cell Physiology in press
Kanda N and Watanabe S (2008) IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes. European Journal of Immunology in press
Kanda N and Watanabe S (2008) Leptin enhances human beta-defensin-2 production in human keratinocytes. Endocrinology in press
Kanda T, Yokosuka O, Kato N, Imazeki F, Fujiwara K, Kawai S, Saisho H and Omata M (2003) Hepatitis A virus VP3 may activate serum response element associated transcription. Scandanavian Journal of Gastroenterology 38 307-313
Kanda T, Yokosuka O, Nagao K and Saisho H (2006) State of hepatitis C viral replication enhances activation of NF-kB- and AP-1-singaling induced by hepatitis B virus X. Cancer Letters 234 143-148
Kandarian SC and Jackman RW (2006) Intracellular signaling during skeletal muscle atrophy. Muscle Nerve 33 155-165
Kandel ES, Lu T, Wan Y, Agarwal MK, Jackson MW and Stark GR (2005) Mutagenesis by reversible promoter insertion to study the activation of NF-kB. Proceedings of the National Academy of Sciences USA 102 6425-6430
Kandimalla ER, Bhagat L, Wang D, Yu D, Zhu FG, Tang J, Wang H, Huang P, Zhang R and Agrawal S (2003) Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles. Nucleic Acids Research 31 2393-2400
Kandimalla ER, Bhagat L, Yu D, Cong Y, Tang J and Agrawal S (2002) Conjugation of ligands at the 5′-end of CpG DNA affects immunostimulatory activity. Bioconjug Chem 13 966-974
Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, Wang D, Tang JX, Tang JY, Knetter CF, Lien E and Agrawal S (2003) A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif. Proceedings of the National Academy of Sciences USA 100 14303-14308
Kandouz M, Nie D, Pidgeon GP, Krishnamoorthy S, Maddipati KR and Honn KV (2003) Platelet-type 12-lipoxygenase activates NF-kB in prostate cancer cells. Prostaglandins and Other Lipid Mediators 71 189-204
Kane CM, Cervi L, Sun J, McKee AS, Masek KS, Shapira S, Hunter CA and Pearce EJ (2004) Helminth antigens modulate TLR-initiated dendritic cell activation. Journal of Immunology 173 7454-7461
Kane LP, Lin J and Weiss A (2002) It’s all Rel-ative: NF-kB and CD28 costimulation of T-cell activation. Trends in Immunology 23 413-420
Kane LP, Mollenauer MN, Xu Z, Turck CW and Weiss A (2002) Akt-dependent phosphorylation specifically regulates Cot induction of NF-kB-dependent transcription. Molecular and Cellular Biology 22 5962-5974
Kane LP, Shapiro VS, Stokoe D and Weiss A (1999) Induction of NF-kB by the Akt/PKB kinase. Current Biology 9 601-604
Kanegae Y, Taveres AT, Belmonte JCI and Verma IM (1998) Role of Rel/NF-kB transcription factors during the outgrowth of the vertebrate limb. Nature 392 611-614
Kanekiyo M, Itoh N, Kawasaki A, Tanaka J, Nakanishi T and Tanaka K (2001) Zinc-induced activation of the human cytomegalovirus major immediate-early promoter is mediated by metallothionein and nuclear factor-kB. Toxicology and Applied Pharmacology 173 146-153
Kaneko K, Smetana-Just U, Matsui M, Young AR, John S, Norval M and Walker SL (2008) cis-Urocanic acid initiates gene transcription in primary human keratinocytes. Journal of Immunology 181 217-224
Kaneko M, Niinuma Y and Nomura Y (2003) Activation signal of nuclear factor-kB in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2. Biological & Pharmaceutical Bulletin 26 931-935
Kaneko M, Takahashi T, Niinuma Y and Nomura Y (2004) Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-kB and AP-1 activation. Biological & Pharmaceutical Bulletin 27 1202-1206
Kaneko T, Fujii S, Matsumoto A, Goto D, Makita N, Hamada J, Moriuchi T and Kitabatake A (2003) Induction of tissue factor expression in endothelial cells by basic fibroblast growth factor and its modulation by fenofibric acid. Thrombosis Journal 1 6
Kaneko T and Silverman N (2005) Bacterial recognition and signalling by the Drosophila IMD pathway. Cellular Microbiology 7 461-469
Kaneko T, Yano T, Aggarwal K, Lim JH, Ueda K, Oshima Y, Peach C, Erturk-Hasdemir D, Godlman WE, Oh BH, Kurata S and Silverman N (2006) PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan.
Nature Immunology 7 715-723
Kaneko Y, Furukawa S, Tanaka H and Yamakawa M (2007) Expression of antimicrobial peptide genes encoding enbocin and gloverin isoforms in the silkworm, Bombyx mori.Bioscience, Biotechnology, and Biochemistry in press
Kanekura T, Goora S, Kirtikara K and Ballou LR (2002) The involvement of NF-kB in the constitutive overexpression of cyclooxygenase-2 in cyclooxygenase-1 null cells. Biochimica et Biophysica Acta 1542 14-22
Kanematsu M, Yoshimura K, Takaoki M and Sato A (2002) Vector-averaged gravity regulates gene expression of receptor activator of NF-kB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway. Bone 30 553-558
Kanetaka Y, Hayashida M, Hoshika A, Yanase N and Mizuguchi J (2007) Interferon-a induces transient upregulation of c-FLIP through NF-kB activation. Experimental Cell Research in press
Kang BN, Jude JA, Panethieri Jr RA, Walseth TF and Kannan MS (2008) Glucocorticoid regulation of CD38 expression in human airway smotth muscle cells: role of dual specificiaty phosphatase 1. American Journal of Physiology: Lung Cell and Molecular Physiology in press
Kang B, Liang Y, Shan Y, Guo M, Liu S, Fu X, Cao H, Wu M and Wang H (2005) SIRPalpha negatively regulates differentiation of PC12 cell. Brain Research Molecular Brain Research 138 205-214
Kang BN, Tirumurugaan KG, Deshpande DA, Amrani Y, Panettieri RA, Walseth TF and Kannan MS (2006) Transcriptional regulation of CD38 expression by tumor necrosis factor-a in human airway smooth muscle cells: role of NF-kB and sensitivity to glucocorticoids. FASEB Journal 20 1000-1002
Kang BP, Frencher S, Reddy V, Kessler A, Malhotra A and Meggs LG (2002) High glucose promotes mesangial cell apoptosis by an oxidant dependent mechanism. American Journal of Physiology: Renal Physiology 284 F455-F466
Kang BY, Chung SW and Kim TS (2001) Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-kB. Immunology Letters 77 159-163
Kang BY, Chung SW, Chung W, Im S, Hwang SY and Kim TS (1999) Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin. European Journal of Pharmacology 384 191-195
Kang BY, Chung SW, Im SY, Hwang SY and Kim TS (1999) Chloromethyl ketones inhibit interleukin-12 production in mouse macrophages stimulated with lipopolysaccharide. Immunology Letters 70 135-138
Kang BY, Chung SW, Kim SH, Cho D and Kim TS (2003) Involvement of nuclear factor-kB in the inhibition of interleukin-12 production from mouse macrophages by baicalein, a flavonoid in Scutellaria baicalensis. Planta Med 69 687-691
Kang BY, Kim E and Kim TS (2005) Regulatory mechanisms and their therapeutic implications of interleukin-12 production in immune cells. Cellular Signaling 17 665-673
Kang BY, Kim S, Lee KH, Lee YS, Hong I, Lee MO, Min D, Chang I, Hwang JS, Park JS, Kim DH and Kim BG (2008) Transcriptional profiling in human HaCaT keratinocytes in response to kaempferol and identification of potential transcription factors for regulating differential gene expression. Experimental and Molecular Medicine 40 208-219
Kang BY, Kim SH, Cho D and Kim TS (2005) Inhibition of interleukin-12 production in mouse macrophages via decreased nuclear factor-kappaB DNA binding activity by myricetin, a naturally occurring flavonoid. Archives in Pharmacal Research 28 274-279
Kang BY, Miaw SC and Ho IC (2005) ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation. Molecular and Cellular Biology 25 554-562
Kang CD, Han CS, Kim KW, Do IR, Kim CM, Kim SH, Lee EY and Chung BS (1998) Activation of NF-kB mediates the PMA-induced differentiation of K562 cells. Cancer Letters 132 99-106
Kang C-Y and Temin HM (1973) Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. Journal of Virology 12 1314-1324
Kang C-Y and Temin HM (1974) Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. Journal of Virology 14 1179-1188
Kang DG, Moon MK, Choi DH, Lee JK, Kwon TO and Lee HS (2005) Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-d-glucose (PGG) via a nitric oxide-cGMP pathway. European Journal of Pharmacology 524 111-119
Kang DG, Moon MK, Lee AS, Kwon TO, Kim JS and Lee HS (2007) Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells.
Biological & Pharmaceutical Bulletin 30 1796-1799
Kang DS, Kwon CH, Park JY, Kim JH, Woo JS, Jung JS and Kim YK (2006) 15-Deoxy-Delta(12,14)-prostaglandin J(2) induces renal epithelial cell death through NF-kB-dependent and MAPK-independent mechanism. Toxicology and Applied Pharmacology 216 426-435
Kang DW, Park MH, Lee YJ, Kim HS, Kwon TK, Park WS and Min DS (2008) Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/ras/ERK/NFkB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells. Journal of Biological Chemistry 283 4094-4104
Kang ES, Kim Gh, Kim HJ, Woo IS, Ham SA, Jin H, Kim MY, Kim HJ, Lee JH, Chang KC, Seo HG and Hwang JY (2008) Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kB. Pharmacology Research in press
Kang ES, Kim HJ, Paek KS, Jang HS, Chang KC, Lee JH, Nishinaka T, Yabe-Nishimura C and Seo HG (2005) Phorbol ester up-regulates aldose reductase expression in A549 cells: a potential role for aldose reductase in cell cycle modulation. Cell and Molecular Life Sciences 62 1146-1155
Kang G, Kong PJ, Yuh YJ, Lim SY, Yim SV, Chun W and Kim SS (2004) Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression by inhibiting activator protein 1 and nuclear factor kB bindings in BV2 microglial cells. Journal of Pharmacological Sciences 94 325-328
Kang HB, Kim YE, Kwon HJ, Sok DE and Lee Y (2007) Enhancement of NF-kB expression and activity upon differentiation of human embryonic stem cell line SNUhES3. Stem Cells and Development 16 615-624
Kang J, Park EJ, Jou I, Kim JH and Joe EH (2001) Reactive oxygen species mediate A beta(25-35)-induced activation of BV- 2 microglia. Neuroreport 12 1449-1452
Kang JH, Kim CS, Han IS, Kawada T and Yu R (2007) Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages. FEBS Letters in press
Kang J-H, Sung M-K, Kawada T, Yoo H, Kim Y-K, Kim J-S and Yu R (2005) Soybean saponins suppress the release of proinflammatory mediators by LPS-stimulated peritoneal macrophages. Cancer Letters 230 219-227
Kang JL, Go YH, Hur KC and Castranova V (2000) Silica-induced nuclear factor-kB activation: involvement of reactive oxygen species and protein tyrosine kinase activation. Journal of Toxicology and Environmental Health 60 27-46
Kang JL, Jung HJ, Lee K and Kim HR (2006) Src tyrosine kinases mediate crystalline silica-induced NF-kB activation through tyrosine phosphorylation of IkB-a and p65 NF-kB in RAW 264.7 macrophages. Toxicological Sciences 90 470-477
Kang JL, Lee HS, Jung HJ and Kim HJ (2003) Iron tetrakis (N-methyl-4′-pyridyl) porphyrinato inhibits proliferative activity of thymocytes by blocking activation of p38 mitogen-activated protein kinase, nuclear factor-kB, and interleukin-2 secretion. Toxicology and Applied Pharmacology 191 147-155
Kang JL, Lee HS, Jung HJ, Kim HJ, Hah JS and Castranova V (2002) Inhibition of mitogenic stimulant-induced activation of thymocytes with zinc tetrakis-(N-methyl-4′-pyridyl) porphyrinato. Journal of Pharmacology and Experimental Therapeutics 303 1138-1144
Kang JL, Lee HW, Lee HS, Pack IS, Chong Y, Castranova V and Koh Y (2001)Genistein prevents nuclear factor-kB activation and acute lung injury induced by lipopolysaccharide. American Journal of Respiratory and Critical Care Medicine 164 2206-2212
Kang JL, Lee HS, Pack IS, Hur KC and Castranova V (2003) Phosphoinositide 3-kinase activity leads to silica-induced NF-kB activation through interacting with tyrosine-phosphorylated IkB-a and contributing to tyrosine phosphorylation of p65 NF-kB. Molecular and Cellular Biochemistry 248 17-24
Kang JL, Lee HS, Pack IS, Leonard S and Castranova V (2001) Iron tetrakis (n-methyl-4′-pyridyl) porphyrinato (FeTMPyP) is a potent scavenging antioxidant and an inhibitor of stimulant-induced NF-kB activation of raw 264.7 macrophages. Journal of Toxicology and Environmental Health 64 291-310
Kang JL, Lee HW, Kim HJ, Lee HS, Castrovnova V, Limm CM and Koh Y (2005) Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kB, and serine and tyrosine phosphorylation of IkB-a in lipopolysaccharide-stimulated Raw 264.7 macrophages. Journal of Toxicology and Environmental Health 68 1643-1662
Kang JL, Pack IS, Hong SM, Lee HS, Castranova V (2000) Silica induces nuclear factor-kB activation through tyrosine phosphorylation of IkB-a in RAW264.7 macrophages. Toxicology and Applied Pharmacology 169 59- 65
Kang JL, Pack IS, Hong SM, Lee HS, Hah JS, Nam W, Leonard S and Castranova V (2001) Zinc tetrakis(N-methyl-4′-pyridyl) porphyrinato is an effective inhibitor of stimulant-induced activation of RAW 264.7 cells. Toxicology and Applied Pharmacology 172 140-149
Kang JL, Park W, Pack IS, Lee HS, Kim MJ, Lim CM and Koh Y (2002) Inhaled nitric oxide attenuates acute lung injury via inhibition of nuclear factor-kB and inflammation. Journal of Applied Physiology 92 795-801
Kang JS, Jeon YJ, Park SK, Yang KH and Kim HM (2004) Protection against lipopolysaccharide-induced sepsis and inhibition of interleukin-1beta and prostaglandin E2 synthesis by silymarin. Biochemical Pharmacology 67 175-181
Kang JS, Jeon YJ, Suh J, Park SK, Yang KH and Kim HM (2004) 2-Acetylaminofluorene inhibits interleukin-1beta production in LPS-stimulated macrophages by blocking NF-kB/Rel activation. Cancer Letters 203 91-98
Kang JS, Park SK, Yang KH and Kim HM (2003) Silymarin inhibits TNF-alpha-induced expression of adhesion molecules in human umbilical vein endothelial cells. FEBS Letters 550 89-93
Kang JS, Yoon YD, Cho IJ, Han MH, Lee CW, Park SK and Kim HM (2004) Glabridin, an isoflavan from licorice root, inhibits inducible nitric oxide synthase expression and improves survival of mice in experimental model of septic shock. Journal of Pharmacology and Experimental Therapy 312 1187-1194
Kang JS, Yoon YD, Han MH, Han SB, Lee K, Kang MR, Moon EY, Jeon YJ, Park SK and Kim HM (2005) Estrogen receptor-independent inhibition of tumor necrosis factor-alpha gene expression by phytoestrogen equol is mediated by blocking nuclear factor-kB activation in mouse macrophages. Biochemical Pharmacology 71 136-143
Kang JS, Yoon YD, Han MH, Han SB, Lee K, Lee KH, Park SK and Kim HM (2006) Glabridin suppresses intercellular adhesion molecule-1 expression in TNF-a-stimulated human umbilical vein endothelial cells by blocking sphingosine kinase pathway: implications of Akt, ERK and NF-kB/Rel signaling pathways. Molecular Pharmacology 69 941-949
Kang JS, Yoon YD, Han MH, Han SB, Lee K, Park SK and Kim HM (2007) Equol inhibits nitric oxide production and inducible nitric oxide synthase gene expression through down-regulating the activation of Akt. International Immunopharmacology 7 491-499
Kang K, Kim H, Kim KI, Yang Y, Yoon DY, Kim JH, Ryu JH, Noh EJ, Jeon SD and Lim JS (2007) SK-126, a synthetic compound, regulates the production of inflammatory cytokines induced by LPS in antigen-presenting cells. Biochemical Pharmacology in press
Kang KA, Lee KH, Zhang R, Piao MJ, Kang MY, Kwak YS, Yoo BS, You HJ and Hung JW (2007) Protective effects of Castanopsis cuspidate through activation of ERK and NF-kB on oxidative cell death induced by hydrogen peroxide. Journal of Toxicology and Environmental Health A 70 1319-1328
Kang KN, Kim M, Pae KM and Lee ST (2002) Characterization of the 5′-flanking region of the human PTK6 gene. Biochimica et Biophysica Acta 1574 365-369
Kang KS, Kim HY, Yamabe N, Park JH and Yokozawa T (2007) Preventive effect of 20(S)-ginsenoside Rg(3) against lipopolysaccharide-induced hepatic and renal injury in rats. Free Radical Research 41 1181-1188
Kang KS, Yamabe N, Kim HY and Yokozawa T (2007) Effect of sun ginseng methanol extract on lipopolysaccharide-induced liver injury in rats. Phytomedicine in press
Kang KS, Yamabe N, Kim HY and Yokozawa T (2008) Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies. J Pharm Pharmacol 60 445-452
Kang KW, Choi SY, Cho MK, Lee CH and Kim SG (2003) Thrombin induces nitric oxide synthase via Galpha 12/13-coupled PKC-dependent IkBa phosphorylation and JNK-mediated IkBa degradation. Journal of Biological Chemistry 278 17368-17378
Kang KW, Wagley Y, Kim HW, Pokharel YR, Chung YY, Chang IY, Kim JJ, Moon JS, Kim YK, HNah SY, Kang HS and Oh JW (2007) Novel role of IL-6/SIL-6R signaling in the expression of inducible nitric oxide synthase (iNOS) in murine B16, metastatic melanoma clone F10.9, cells. Free Radical Biology and Medicine 42 215-227
Kang L, McIntyre KW, Gillooly KM, Yang Y, Haycock J, Roberts S, Khanna A, Herpin TF, Yu G, Wu X, Morton GC, Tuerdi H, Koplowitz B, Walker SG, Wardwell-Swanson J, Macor JE, Lawrence RM and Carlson KE (2006) A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice. Journal of Leukoctye Biology 80 897-904
Kang MH, So EY, Park H and Kim BS (2008) Replication of Theiler’s virus requires NF-kB-activation: higher viral replication and spreading in astrocytes from susceptible mice. Glia in press
Kang MK, Jhee EC, Koo BS, Yang JY, Park BH, Kim JS, Rho HW, Kim HR and Park JW (2002) Induction of nitric oxide synthase expression by Vibrio vulnificus cytolysin. Biochemical and Biophysica Research Communications 290 1090-1095
Kang MK, Yoon YE, Yang JY, Kwon KB, Park JW and Jhee EC (2004) Protective effect of retinoic acid on interleukin-1beta-induced cytotoxicity of pancreatic beta-cells. Mechanisms of Ageing & Development 125 483-490
Kang MW, Jang JY, Choi JY, Kim SH, Oh J, Cho BS and Lee CE (2008) Induction of IFN-g gene expression by thioredoxin: positive feed-back regulation of Th1 response by thioredoxin and IFN-g. Cellular Physiology and Biochemistry 21 215-224
Kang NY, Kang SK, Lee YC, Choi HJ, Lee YS, Cho SY, Kim YS, Ko JH and Kim CH (2006) Transcriptional regulation of the human GD3 synthase gene expression in Fas-induced Jurkat T cells: a critical role of transcription factor of NF-kB for regulated expression. Glycobiology 16 375-389
Kang NY, Kim CH, Kim KS, Ko JH, Lee JH, Jeong YK and Lee YC (2007) Expression of the human CMP-NeuAc:GM3 alpha2,8-sialyltransferase (GD3 synthase) gene through the NF-kB activation in human melanoma SK-MEL-2 cells. Biochimica et Biophysica Acta in press
Kang OH, Chae HS, Choi JH, Choi HJ, Park PS, Cho SH, Lee Gh, So HY, Choo YK, Kweon OH and Kwon DY (2006) Effects of the schisandra fructus water extract on cytokine release from a human mast cell line. Journal of Medicinal Food 9 480-486
Kang OH, Choi YA, Park HJ, Kang CS, Song BS, Choi SC, Nah YH, Yun KJ, Cai XF, Kim YH, Bae KH and Lee YM (2006) Inhibition of trypsin-induced mast cell activation by acanthoic acid. Journal of Ethnopharmacology 10-5 326-331
Kang OH, Kim JA, Choi YA, Park HJ, Kim DK, An YH, Choi SC, Yun KJ, Nah YH, Cai XF, Kim YH, Bae KH and Lee YM (2005) Inhibition of interleukin-8 production in the human colonic epithelial cell line HT-29 by 18beta-glycyrrhetinic acid. International Journal of Molecular Medicine 15 981-985
Kang OH, Lee GH, Choi HJ, Park PS, Chae HS, Jeong SI, Kim YC, Sohn DH, Park H, Lee JH and Kwon DY (2007) Ethyl acetate extract from Angelica Dahuricae Radix inhibits lipopolysaccharide-induced production of nitric oxide, prostaglandin E(2) and tumor necrosis factor-alphavia mitogen-activated protein kinases and nuclear factor-kB in macrophages. Pharmacological Research 55 263-270
Kang S, Kim YB, Kim MH, Yoon KS, Kim JW, Park NH, Song YS, Kang D, Yoo KY, Kang SB and Lee HP (2005) Polymorphism in the nuclear factor kappa-B binding promoter region of cyclooxygenase-2 is associated with an increased risk of bladder cancer. Cancer Letters 217 11-16
Kang S-M, Tran A-C, Grilli M and Lenardo MJ (1992) NF-kB subunit regulation in nontransformed CD4+ T lymphocytes. Science 256 1452-1456
Kang SN, Kim SH, Chung SW, Lee MH, Kim HJ and Kim TS (2002) Enhancement of 1 alpha,25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kB activity. British Journal of Pharmacology 135 1235-1244
Kang SS, Cuendet M, Endringer DC, Croy VL, Pezzuto JM and Lipton MA (2008) Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kB. Biorganic Medicinal Chemistry in press
Kang SS, Woo SS, Kim J, Yang JS, Yun CH, Ju HR, Son CG, Moon EY and Han SH (2007) Human placenta promotes IL-8 expression through activation of JNK/SAPK and transcription factors NF-kB and AP-1 in PMA-differentiated THP-1 cells.International Immunopharmacology 7 1488-1495
Kang W, Saito H, Fukatsu K, Nagawa H and Ikeda S (2003) Brief refeeding rapidly reverses dietary restriction-induced nuclear factor-kappaB downregulation in peritoneal resident cells. JPEN J Parenter Enteral Nutr 27 193-197
Kang YH, Lee KA, Ryu CJ, Lee HG, Lim JS, Park SN, Paik SG and Yoon DY (2006) Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells. Cancer Letters i237 33-44
Kang YH, Lee KA, Yang Y, Kim SH, Kim JH, Park SN, Paik SG and Yoon DY (2007) The apoptotic effect of intercalating agents on HPV-negative cervical cancer C-33A cells. Amino Acids in press
Kang YJ, Chen J, Otsuka M, Mols J, Ren S, Wang Y and Han J (2008) Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation. Journal of Immunology 180 5075-5082
Kang YJ, Kim SO, Shimada S, Otsuka M, Seit-Nebi A, Kwon BS, Watts Th and Han J (2007) Cell surface 4-1BBL mediates sequential signaling pathways ‘downstream’ of TLR and is required for sustained TNF production in macrophages. Nature Immunology in press
Kang YJ, Kusler B, Otsuka M, Hughes M, Suzuki N, Suzuki S, Yeh WC, AKira S, Han J and Jones PP (2007) Calcineurin negatively regulates TLR-mediated activation pathways. Journal of Immunology 179 4598-4607
Kang YJ, Lee YS, Lee GW, Lee DH, Ryu JC, Yun-Choi HS and Chang KC (1999) Inhibition of activation of nuclear factor kappaB is responsible for inhibition of inducible nitric oxide synthase expression by higenamine, an active component of aconite root. Journal of Pharmacology and Experimental Therapy 291 314-320
Kang YJ, Lee BK, Lee YS, Seo HG, Park MK, Kim HJ, Pyo HS, Chong WS, Jung HJ, Yun-Choi HS, Lee DH and Chang KC (2003) Suppression of tumor necrosis factor-a and inducible nitric oxide synthase gene expression by THI 52, a new synthetic naphthyl-benzylisoquinoline alkaloid. Biochemical Pharmacology 65 457-464
Kang YJ, Wingerd BA, Arakawa T and Smith WL (2006) Cyclooxygenase-2 gene transcription in a macrophage model of inflammation. Journal of Immunology 177 8111-8122
Kang YM, Kim SY, Kang JH, Han SW, Nam EJ, Kyung HS, Park JY and Kim IS (2007) Light up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes. Arthritis andRheumatism 56 1106-1111
Kang YM, Ma Y, Elks C, Zhang JP, Yang ZM and Francis J (2008) Cross talk between cytokines and renin-angiotensin in hypothalamic paraventricular nucleus in heart failure: role of nuclear factor-kB. Cardiovascular Research in press
Kania J, Baranska A and Guzdek A (2003) Cytokine action and oxidative stress response in differentiated neuroblastoma SH-SY5Y cells. Acta Biochim Pol 50 659-666
Kaniowskia D, Kaminski R, Amini S, Radhakrishnan S, Rappaport J, Johnson E, Khalili K, Del Valle L and Darbinyan A (2006) Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) Tat modulates transcription of the HIV-1 long terminal repeat in glial cells. Journal of Virology 80 9288-9299
Kanke T, Takizawa T, Kabeya M and Kawabata A (2005) Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2 as a potential therapeutic target. Journal of Pharmacological Science 97 38-42
Kankova K, Vojtesek B and Valik D (2001) The Rel/NF-kB transcription factors and their biological functions [Article in Czech]. Cas Lek Cesk 140 163-167
Kannan-Thulasiraman P and Shapiro DJ (2002) Modulators of inflammation use NF-kB and AP-1 sites to induce the caspase-1 and granzyme B inhibitor, proteinase inhibitor 9. Journal of Biological Chemistry 277 41230-41239
Kanneganti TD, Lamkanfi M and Nunez G (2007) Intracellular NOD-like receptors in host defense and disease. Immunity 27 549-559
Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, AKira S and Nunez G (2006) Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 233-236
Kanning KC, Hudson M, Amieux PS, Wiley JC, Bothwell M and Schecterson LC (2003) Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability. Journal of Neuroscience 23 5425-5436
Kanno S, Hiura T, Shouji A, Osani Y, Ujibe M and Ishikawa M (2007) Resistance to Ara-C up-regulates the activation of NF-kB, telomerase activity and Fas expression in NALM-6 cells. Biol Pharm Bulletin 30 2069-2974
Kanno SI, Shouji A, Tomizawa A, Hiura T, Osanai Y, Ujibe M, Obara Y, Nakahata N and Ishikawa M (2005) Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages. Life Sciences 78 673-681
Kanno SI, Tomizawa A, Ohtake T, Koiwai K, Ujibe M and Ishikawa M (2006) Naringenin-induced apoptosis via activation of NF-kB and necrosis involving the loss of ATP in human promyeloleukemia HL-60 cells. Toxicology Letters 166 131-139
Kanno T and Siebenlist U (1996) Activation of nuclear factor kB via T cell receptor requires a Raf kinase and Ca2+ influx. Journal of Immunology 157 5277-5283
Kanno T, Brown K and Siebenlist U (1995) Evidence in support of a role for HTLV-I Tax in activating NF-kB via stimulation of signaling pathways. Journal of Biological Chemistry 270 11745-11748
Kanno T, Brown K, Franzoso G and Siebenlist U (1994) Kinetic analysis of human T-cell leukemia virus type-I Tax-mediated activation of NF-kB. Molecular and Cellular Biology 14 6443-6451
Kanno T, Franzoso G and Siebenlist U (1994) Human T-cell leukemia virus type I Tax protein-mediated activation of NF-kB from p100 (NF-kB2)-inhibited cytoplasmic reserves. Proceedings of the National Academy of Sciences USA 91 12634-12638
Kantengwa S, Jornot L, Devenoges C and Nicod LP (2003) Superoxide anions induce the maturation of human dendritic cells. American Journal of Respiratory and Critical Care Medicine 167 431-437
Kanters E, Gijbels MJ, Van Der Made I, Vergouwe MN, Heeringa P, Kraal G, Hofker MH and De Winther MP (2003) Hematopoietic NF-kB1 deficiency results in smaller atherosclerotic lesions with a more inflammatory phenotype. Blood 103 934-940
Kanters E, Pasparakis M, Gijbels MJ, Vergouwe MN, Partouns-Hendriks I, Fijneman RJ, Clausen BE, Forster I, Kockx MM, Rajewsky K, Kraal G, Hofker MH and De Winther MP (2003) Inhibition of NF-kB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. Journal of Clinical Investigation 112 1176-1185
Kanthasamy A, Kitazawa M, Kaul S, Anantharam V and Kanthasamy AG (2002) A novel oxidative stress dependent apoptotic pathway in pesticide-induced dopaminergic degeneration in PD models. Journal of Neurochemistry 81 76
Kanzaki H, Chiba M, Shimizu Y and Mitani H (2001) Dual regulation of osteoclast differentiation by periodontal ligament cells through RANKL stimulation and OPG inhibition. Journal of Dental Research 80 887-891
Kanzawa N, Nishigaki K, Hayashi T, Ishii Y, Furukawa S, Niiro A< yasui F, Kohara M, Morita K, Matsushima K, Le MQ, Masuda T and Kannagi M (2006) Augmentation of chemokine production by severe acute respiratory syndrome coronavirus 3a/X1 and 7a/X4 proteins through NF-kB activation. FEBS Letters 580 6807-6812
Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW and Wu R (2004) IL-17 markedly up-regulates b-defensin-2 expression in human airway epithelium via JAK and NF-kB signaling pathways. Journal of Immunology 173 3482-3491
Kao CY, Huang F, Chen Y, Thai P, Wachi S, Kim C, Tam L and Wu R (2005) Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kB-dependent signaling pathway. Journal of Immunology 175 6676-6685
Kao CY, Kim C, Huang F and Wu R (2008) Requirements for two proximal NF-kB binding sites and IkB-z in IL-17A-induced human beta -defensin 2 expression by conducting airway epithelium. Journal of Biological Chemistry in press
Kao ES, Wang CJ, Lin WL, Chu CY and Tseng TH (2007) Effects of polyphenols derived from fruit of Crataegus pinnatifida on cell transformation, dermal edema and skin tumor formation by phorbol ester application. Food and Chemical Toxicology in press
Kao JJ (2006) The NF-kB inhibitor pyrrolidine dithiocarbamate blocks IL-1beta induced hyaluronan synthase 1 (HAS1) mRNA transcription, pointing at NF-kB dependence of the gene HAS1. Experimental Gerontology 41 641-647
Kao JY, Pierzchala A, Rathinavelu S, Zavros Y, Tessier A, and Merchant JL (2005) Somatostatin inhibits dendritic cell responsiveness to Helicobacter pylori.Regulatory Peptides 134 23-29
Kao KR and Hopwood ND (1991) Expression of a mRNA related to c-rel and dorsal in early Xenopus laevis embryos. Proceedings of the National Academy of Sciences USA 88 2697-2701
Kao KR and Lockwood A (1996) Negative regulation of dorsal patterning in early embryos by overexpression of XrelA, a Xenopus homologue of NF-kB. Mechanisms of Development 58 129-139
Kao SJ, Lei HC, Kuo CT, Chang MS, Chen BC, Chang YC, Chiu WT and Lin CH (2005) Lipoteichoic acid induces nuclear factor-kappaB activation and nitric oxide synthase expression via phosphatidylinositol 3-kinase, Akt, and p38 MAPK in RAW 264.7 macrophages. Immunology 115 366-374
Kao YH, Goto S, Jawan B, Nakano T, Hsu LW, Lin YC, Pan MC, Lai CY, Sun CK, Cheng YF, Tai MH, Huang HT and Chen CL (2007) Heat preconditioning ameliorates hepatocyte viability after cold preservation and rewarming, and modulates its immunoactivity. Transplantation Immunology 18 220-231
Kao YS and Fong JC (2008) Endothelin-1 induces glut1 transcription through enhanced interaction between Sp1 and NF-kB transcription factors. Cellular Signaling in press
Kapahi P, Takahashi T, Natoli G, Adams SR, Chen Y, Tsien RY and Karin M (2000) Inhibition of NF-kB activation by arsenite through reaction with a critical cysteine in the activation loop of IkB kinase. Journal of Biological Chemistry 275 36062-36066
Kapalla M, Yeghiazaryan K, Hricova M, Moenkemann H, Pirek A, Schild HH and Golubnitschaja O (2005) Combined analysis of biochemical parameters in serum and differential gene expression in circulating leukocytes may serve as an ex vivo monitoring system to estimate risk factors for complications in Diabetes mellitus. Amino Acids 28 221-227
Kapasi AA, Fan S and Singhal PC (2006) Scatter factor mitigates HIV-1 gp120-induced human mesangial cell injury. Nephron and Experimental Nephrology 103 e103-e108
Kapetanovic R, Nahori MA, Balloy V, Fitting C, Philpott DJ, Cavaillon JM and Adib-COnquy M (2006) Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophages. Infection and Immunity in press
Kaplan BL, Ouyang Y, Herring A, Su Yea S, Razdan R and Kaminski NE (2005) Inhibition of leukocyte function and interleukin-2 gene expression by 2-methylarachidonyl-(2′-fluoroethyl)amide, a stable congener of the endogenous cannabinoid receptor ligand anandamide. Toxicology and Applied Pharmacology 205 107-115
Kaplan JM, Cook JA, Hake PW, O’Connor M, Burroughs TJ and Zingarelli B (2005) 15-deoxy-delta12,14-prostaglandin J2 (15D-PJG2), a peroxisome proliferator activated receptor gamma ligand, reduces tissue leukosequestration and mortality in endotoxic shock. Shock 24 59-65
Kapoor GS, Zhan Y, Johnson GR and O’Rourke DM (2004) Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kB activation through Gab1 in glioblastoma cells. Molecular and Cellular Biology 24 823-836
Kappler C, Meister M, Lagueux M, Gateff E, Hoffmann JA and Reichhart JM (1993) Insect Immunity. Two 17 bp repeats nesting a kB-related sequence confer inducibility to the diptericin gene and bind a polypeptide in bacteria-challenged Drosophila. EMBO Journal 12 1561-1568
Karacay B, Sanlioglu S, Griffith TS, Sandler A and Bonthius DJ (2004) Inhibition of the NF-kB pathway enhances TRAIL-mediated apoptosis in neuroblastoma cells. Cancer Gene Therapy 11 681-690
Karadag A, Zhou M and Croucher PI (2006) ADAM-9 (mdc-9/meltrin-{gamma}), a member of the a disintegrin and metalloproteinase family, regulates myeloma cell induced interleukin-6 production in osteoblasts by direct interaction with the {alpha}v{beta}5-integrin. Blood 107 3271-3278
Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O’Brien M, Leeman SE, Kirkland JL and Pothoulakis C (2006) Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes. Proceedings of the National Academy of Sciences USA 103 5207-5212
Karalis KP, Venihaki M, Zhao J, Van Vlerken LE and Chandras C (2004) Nuclear factor-kB participates in the corticotropin releasing hormone-induced regulation of the pituitary proopiomelanocortin gene. Journal of Biological Chemistry 279 10837-10840
Karamenderes C, Konyalioglu S, Khan S and Khan IA (2007) Total phenolic contents, free radical scavenging activities and inhibitory effects on the activation of NF-kB of eight Centaurea L. species. Phytotherapy Research in press
Karashima T, Sweeney P, Kamat A, Huang S, Kim SJ, Bar-Eli M, McConkey DJ and Dinney CP (2003) Nuclear Factor-kB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8. Clinical Cancer Research 9 2786-2797
Karatsaidis A, Hayashi K, Schreurs O, Helgeland K and Schenck K (2007) Survival signalling in keratinocytes of erythematous oral lichen planus. Journal of Oral Pathology and Medicine 36 215-222
Karayiannis P (2005) The hepatitis C virus NS3/4A protease complex interferes with pathways of the innate immune response. Journal of Hepatology 43 743-745
Karban A, Okazaki T, Panhuysen CI, Gallegos T, Potter JJ, Bailey-Wilson JE, Silverberg MS, Duerr RH, Cho J, Gregersen PK, Wu Y, Achkar JP, Dassopoulos T, Mezey E, Bayless TM, Nouvet FJ and Brant SR (2004) Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Human Molecular Genetics 13 35-45
Kariko K, Ni H, Capodici J, Lamphier M and Weissman D (2004) mRNA is an endogenous ligand for toll-like receptor 3. Journal of Biological Chemistry 279 12542-12550
Karimi K, Sarir H, Mortaz E, SMit JJ, Hosseini H, de Kimpe S, Nijkamp F and Folkerts G (2006) Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages Respiratory Research 7 66
Karimipour DJ, Kang S, Johnson TM, Orringer JS, Hamilton T, Hammerberg C, Voorhees JJ and Fisher G (2005) Microdermabrasion: A molecular analysis following a single treatment. Journal of the American Academy of Dermatology 52 215-223
Karin M (1991) Signal transduction and gene control. Current Opinion in Cell Biology 3 467-473
Karin M (1998) The NF-kB activation pathway: its regulation and role inflammation and cell survival. Cancer Journal of Scientific American 4 S92-S99
Karin M (1999) The beginning of the end: IkB kinase (IKK) and NF-kB activation. Journal of Biological Chemistry 274 27339-27342
Karin M (2004) Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs. Annals of Rheumatoid Disease Suppl 2 ii62-ii64
Karin M (2005) Inflammation-activated protein kinases as targets for drug development. Proceedings of the American Thoracic Society 2 386-390
Karin M (2006) NF-kB and cancer: Mechanisms and targets. Molecular Carcinogenesis 45 355-361
Karin M (2006) Nuclear factor-kB in cancer development and progression. Nature 441431-436
Karin M (2006) Role for IKK2 in muscle: waste not, want not. Journal of Clinical Investigation 116 2866-2868
Karin M (2008) The IkB kinase – a bridge between inflammation and cancer. Cell Research in press
Karin M and Delhase M (1998) JNK or IKK, AP-1 or NF-kB, which are the targets for MEK kinase 1 action. Proceedings of the National Academy of Sciences USA 95 9067-9069
Karin M and Delhase M (2000) The IkB kinase (IKK) and NF-kB: key elements of proinflammatory signalling. Seminars in Immunology 12 85-98
Karin M and Greten FR (2005) NF-kB: linking inflammation and immunity to cancer development and progression. Nature Reviews Immunology 5 749-759
Karin M and Hunter T (1995) Transcriptional control by protein phosphorylation: signal transmission from the cell surface. Current Biology 5 747-757
Karin M and Lin A (2002) NF-kB at the crossroads of life and death. Nature Immunology 3 221-227
Karin M, Cao Y, Greten FR and Li ZW (2002) NF-kB incancer: from innocent bystander to major culprit. Nature Reviews on Cancer 2 301-310
Karin M and Lin A (2002) NF-kB at the crossroads of life and death. Nature Immunology 3 221-227
Karin M, Takahashi T, Kapahi P, Delhase M, Chen Y, Makris C, Rothwarf D, Baud V, Natoli G, Guido F and Li N (2001) Oxidative stress and gene expression: The AP-1 and NF-kB connections. Biofactors 15 87-89
Karin M, Yamamoto Y and Wang QM (2004) The IKK NF-kB system: a treasure trove for drug development. Nature Reviews Drug Discovery 3 17-26
Karl E, Warner K, Zeitlin B, Kaneko T, Wurtzel L, Jin T, Chang J, Wang S, Wang CY, Strieter RM, Nunez G, Polverini PJ and Nor JE (2005) Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kB and CXC chemokines. Cancer Research 65 5063-5069
Karlsen A, Retterstol L, Laake P, Paur I, Kjolsrud-Bohn S, Sandvik L and Blomhoff R (2007) Anthocyanins inhibit nuclear factor-kB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. Journal of Nutrition 137 1951-1954
Karlsen AE, Heding PE, Frobose H, Ronn SG, Kruhoffer M, Orntoft TF, Darville M, Eizirik DL, Pociot F, Nerup J, Mandrup-Poulsen T and Billestrup N (2004) Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kB-regulated proapoptotic pathways. Diabetologia 47 1998-2011
Karmakar S, Banik NL and Ray SK (2007) Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice. Cancer in press
Karna E, Miltyk W, Surazynski A and Palka JA (2007) Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta(1)-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes.
Molecular and Cellular Biochemistry in press
Karnoub AE, Der CJ and Campbell SL (2001) The insert region of Rac1 is essential for membrane ruffling but not cellular transformation. Molecular and Cellular Biology 21 2847-2857
Karrasch T and Jobin C (2007) NF-kB and the intestine: friend or foe? InflammatoryBowel Disease in press
Karrasch T, Kim JS, Jang BI and Jobin C (2007) The flavonoid luteolin worsens chemical-induced colitis in NF-kB transgenic mice through blockade of NF-kB-dependent protective molecules. PLoS ONE 2 e596
Karrasch T, Kim JS, Muhlbauer M, Magness St and Jobin C (2007) Gnotobiotic IL-10-/-;NF-kBEGFP mice reveal the critical role of TLR/NF-kB signaling in commensal bacteria-induced colitis. Journal of Immunology 178 6522-6532
Karrasch T, Steinbrecher KA, Allard B, Baldwin AS and Jobin C (2006) Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes. Journal of Cellular Physiology 207 809-815
Kasahara DI,Poynter ME, Othman Z< Hemenway D and van Der Vliet A (2008) Acrolein inhalation suppresses lipopolysaccharide-induced inflammatory cytokine production but does not affect acute airways neutrophilia. Journal of Immunology 181 736-745
Kasai T, Miyauchi K, Yokoyama T, Kojimoto K, Sumiyoshi K, Kubota N, Ikeda E and Daida H (2008) Pioglitazone attenuates neointimal thickening via suppression of the early inflammatory response in a porcine coronary after stenting. Atherosclerosis197 612-619
Kase H, Hattori Y, Jojima T, Okayasu T, Tomizawa A, Suzuki K, Banba N, Monden T, Satoh H, Akimoto K and Kasai K (2007) Globular adiponectin induces adhesion molecule expression through the sphingosine kinase pathway in vascular endothelial cells.Life Sciences 81 939-943
Kase S, Aoki K, Harada T, Harada C, Ohgami K, Shiratori K, Nishi S, Ohno S and Yoshida K (2004) Activation of nuclear factor-kB in the conjunctiva with the epithelial scraping of the mouse cornea and human epidemic keratoconjunctivitis. British Journal of Ophthalmology 88 947-949
Kashanchi F and Brady JN (2005) Transcriptional and post-transcriptional gene regulation of HTLV-1. Oncogene 24 5938-5951
Kashani-Sabet M, Liu Y, Fong S, Desprez PY, Liu S, Tu G, Nosrati M, Handumrongkul C, Liggitt D, Thor AD and Debs RJ (2002) Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice. Proceedings of the National Academy of Sciences USA 99 3878-3883
Kashani-Sabet M, Shaikh L, Miller JR 3rd, Nosrati M, Ferreira CM, Debs RJ and Sagebiel RW (2004) NF-kB in the vascular progression of melanoma. Journal of Clinical Oncology 22 617-623
Kashfi K and Rigas B (2005) Molecular targets of nitric-oxide-donating aspirin in cancer. Biochemistry Society Transactions 33 701-714
Kashiwase K, Higuchi Y, Hirotani S, Yamaguchi O, Hikoso S, Takeda T, Watanabe T, Taniike M, Nakai A, Tsujimoto I, Matsumura Y, Ueno H, Nishida K, Hori M and Otsu K (2004) CaMKII activates ASK1 and NF-kB to induce cardiomyocyte hypertrophy. Biochemical and Biophysical Research Communications 327 136-142
Kasibhatla S, Brunner T, Genestier L, Echeverri F, Mahboubi A and Green DR (1998) DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kB and AP-1. Molecular Cell 1 543-551
Kasibhatla S, Genestier L and Green DR (1999) Regulation of Fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kB. Journal of Biological Chemistry 274 987-992
Kasinski AI, Du Y, Thomas SI, Zhao J, Sun S-Y, Khuri FR, Wang C-Y, Shoji M, Sun A, Snyder JP, Liotta D and Fu H (2008) Inhibition of IKK-NF-kB signaling pathway by EF24,a novel monoketone analogue of curcumin. Molecular Pharmacology in press
Kasof GM, Lu JJ, Liu D, Speer B, Mongan KN, Gomes BC and Lorenzi MV (2001) Tumor Necrosis Factor-a induces expression of DR6, a member of the TNF receptor family, through activation of NF-kB. Oncogene 20 7965-7975
Kasperczyk H, La Ferla-Bruhl K, Westhoff MA, Behrend L, Zwacka RM, Debatin KM and Fulda S (2005) Betulinic acid as new activator of NF-kB: molecular mechanisms and implications for cancer therapy. Oncogene 24 6945-6956
Kasravi F, Lee DH and Harris HW (2003) Chylomicron-bound LPS selectively inhibits the TNF-alpha signaling pathway in rat hepatocytes. Journal of Surgical Research 114 287
Kassardjian A and Kreydyyeh SI (2008) JNK modulates the effect of caspases and NF-kB in the TNF-a-induced down-regulation of Na(+)/K(+)ATPase in HepG2 cells. Journal of Cellular Physiology in press
Kassed C, Willing A, Garbuzova-Davis S, Sanberg P and Pennypacker K (2002) Lack of NF-kB p50 exacerbates degeneration of hippocampal neurons after chemical exposure and impairs learning. Experimental Neurology 176 277-288
Kassed CA, Butler TL, Navidomskis MT, Gordon MN, Morgan D and Pennypacker KR (2003) Mice expressing human mutant presenilin-1 exhibit decreased activation of NF-kB p50 in hippocampal neurons after injury. Brain Research Molecular Brain Research 110 152-157
Kassed CA, Butler TL, Patton GW, De Mesquita DD, Navidomskis MT, Memet S, Israel A and Pennypacker KR (2004) Injury-induced NF-kB activation in the hippocampus: implications for neuronal survival.
FASEB Journal 18 723-734
Kassed CA and Herkenham M (2004) NF-kappaB p50-deficient mice show reduced anxiety-like behaviors in tests of exploratory drive and anxiety. Behavior Brain Research 154 577-584
Kassel O, Schneider S, Heilbock C, Litfin M, Gottlicher M and Herrlich P (2004) A nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kB-regulated promoters. Genes & Development 18 2518-2528
Kast RE (2005) Evidence of a mechanism by which etanercept increased TNF-alpha in multiple myeloma: New insights into the biology of TNF-alpha giving new treatment opportunities-the role of bupropion. Leukemia Research 29 1459-1463
Kast RE (2006) Aspirin, TNF-a, NFkB, and survival in multiple myeloma: the importance of measuring TNF-a. Inflammopharmacology in press
Kastenbauer S, Koedel U, Weih F, Ziegler-Heitbrock L and Pfister HW (2004) Protective role of NF-kB1 (p50) in experimental pneumococcal meningitis. Circulation European Journal of Pharmacology 498 315-318
Kastl SP, Speidl WS, Kaun C, Rega G, Assadian A, Weiss TW, Valent P, Hagmueller GW, Maurer G, Huber K and Wojita J (2006) The complement component C5a induces the expression of plasminogen activator inhibitor-1 in human macrophages via NF-kB activation. Journal of Thrombosis and Haemostosis 4 1790-1797
Kastner DL (2005) Hereditary periodic Fever syndromes. Hematology (American Society of Hematology Education Program) 74-81
Kasuga C, Ebata T, Kayagaki N, Yagita H, Hishii M, Arai H, Sato Ka nd Okumura K (2004) Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kB inhibitors. Cancer Science 95 840-844
Kasza A, Kiss DL, Gopalan S, Xu W, Rydel RE, Koj A and Kordula T (2002) Mechanism of plasminogen activator inhibitor-1 regulation by oncostatin M and interleukin-1 in human astrocytes. Journal of Neurochemistry 83 696-703
Kaszkin M, Beck KF, Koch E, Erdelmeier C, Kusch S, Pfeilschifter J and Loew D (2004) Downregulation of iNOS expression in rat mesangial cells by special extracts of Harpagophytum procumbens derives from harpagoside-dependent and independent effects. Phytomedicine 11 585-595
Kaszubska W, Hooft van Huijsduijnen R, Ghersa P, DeRaemy-Schenk A-M, Chen BPC, Hai T, DeLamarter JF and Whelan J (1993) Cyclic AMP-independent ATF family members interact with NF-kB and function in the activation of the E-selectin promoter in response to cytokines. Molecular and Cellular Biology 13 7180-7190
Katafuchi T, Kondo T, Take S and Yoshimura M (2005) Enhanced expression of brain interferon-alpha and serotonin transporter in immunologically induced fatigue in rats. European Journal of Neuroscience 22 2817-2826
Katafuchi T, Takaki A, Take S, Kondo T and Yoshimura M (2003) Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Research Molecular Brain Research 118 24-32
Katagiri D, Hayashi H, Victoriano AF, Okamoto T and Onozaki K (2006) Estrogen stimulates transcription of human immunodeficiency virus type 1 (HIV-1).International Immunopharmacology 6 170-181
Katagiri T and Takahashi N (2002) Regulatory mechanisms of osteoblast and osteoclast differentiation. Oral Disease 8 147-159
Katakai T, Hara T, Sugai M, Gonda H and Shimizu A (2004) Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes. Journal of Experimental Medicine 200 783-795
Katano H, Pesnicak L and Cohen JI (2004) Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas. Proceedings of the National Academy of Sciences USA 101 4960-4965
Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J (2000) The caspase-8 inhibitor FLIP promotes activation of NF-kB and Erk signaling pathways. Current Biology 10 640-648
Kataoka Y, Murley JS, Khodarev NN, Weichselbaum RR and Grdina DJ (2002) Activation of the nuclear transcription factor kB (NFkB) and differential gene expressionin U87 glioma cells after exposure to the cytoprotector amifostine. Int J Radiat Oncol Biol Phys 53 180-189
Kataoka T and Tschopp J (2004) N-Terminal Fragment of c-FLIP(L) Processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kB signaling pathway. Molecular and Cellular Biology 24 2627-2636
Katarina K, Daniela P, Peter N, Marianna R, Pavlina C, Stepanka P, Jan L, Ludmila T, Michal A and Marie C (2007) HLA, NFKB1 and NFKBIA gene polymorphism profile in autoimmune diabetes mellitus patients. Experimental and Clinical Endocrinology & Diabetes 115 124-129
Katdare M, Efimova EV, Labay E, Khodarev NN, Darga TE, Garofalo M, Nakamura S, Kufe DW, Posner MC and Weichselbaum RR (2007) Diverse TNFa-induced death pathways are enhanced by inhibition of NF-kB. International Journal of Oncology 31 1519-1528
Katerinaki E, Haycock JW, Lalla R, Carlson KE, Yang Y, Hill RP, Lorigan PC and MacNeil S (2006) Sodium salicylate inhibits TNF-a-induced NF-kB activation, cell migration, invasion and ICAM-1 expression in human melanoma cells. Melanoma Research16 11-22
Katiyar SK (2008) Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system. Molecular Nutrition and Food Research 52 S71-S76
Katiyar SK and Meeran SM (2007) Obesity increases the risk of UV radiation-induced oxidative stress and activation of MAPK and NF-kB signaling. Free Radical Biology and Medicine 42 299-310
Kato A, Edwards MJ and Lentsch AB (2002) Gene deletion of NF-kB p50 does not alter the hepatic inflammatory response to ischemia/reperfusion. Journal of Hepatology 37 48-55
Kato A, Favoreto Jr S, Avila PC and Schleimer RP (2007) TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. Journal of Immunology 179 1080-1087
Kato A, Homma T, Batchelor J, Hashimoto N, Imai S, Wakiguchi H, Saito H and Matsumoto K (2003) Interferon-a/b receptor-mediated selective induction of a gene cluster by CpG oligodeoxynucleotide 2006. BMC Immunology 4 8
Kato A, Ogasawara T, Homma T, Batchelor J, Imai S, Wakiguchi H, Saito H and Matsumoto K (2004) CpG oligodeoxynucleotides directly induce CXCR3 chemokines in human B cells. Biochemical and Biophysical Research Communications 320 1139-1147
Kato A, Ogasawara T, Homma T, Saito H and Matsumoto K (2004) Lipopolysaccharide-binding protein critically regulates lipopolysaccharide-induced IFN-beta signaling pathway in human monocytes. Journal of Immunology 172 6185-6194
Kato I, Oya T, Suzuki H, Takasawa K, Ichsan AM, Nakada S, Ishiii Y, Shimada Y, Sasahara M, Tobe K, Takasawa S, Okamoto H and Hiraga K (2008) A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells. Diabetes and Metabolism Research Reviews in press
Kato N, Motohashi S, Okada T, Ozawa T and Mashima K (2008) PICOT, protein kinase C theta-interacting protein, is a novel regulator of FcepsilonRI-mediated mast cell activation. Cellular Immunology in press
Kato N, Yoshida H, Kioko Ono-Nita S, Kato J, Goto T, Otsuka M, Lan K, Matsushima K, Shiratori Y and Omata M (2000) Activation of intracellular signaling by hepatitis B and C viruses: C- viral core is the most potent signal inducer. Hepatology 32 405-412
Kato S, Yuzawa Y, Tsuboi N, Maruyama S, Morita Y, Matsuguchi T and Matsuo S (2004) Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4. Journal of American Society of Nephrology 15 1289-1299
Kato Jr T, Delhase M, Hoffmann A and Karin M (2003) CK2 is a C-terminal IkB kinase reponsible for NF-kB activation during the UV response. Molecular Cell 12 829-839
Kato T, Duffey DC, Ondrey FG, Dong G, Chen Z, Cook JA, Mitchell JB and Van Waes C (2000) Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kB. Head and Neck 22 748-759
Kato T, Imatani T, Minaguchi K, Saitoh E and Okuda K (2002) Salivary cystatins induce interleukin-6 expression via cell surface molecules in human gingival fibroblasts. Molecular Immunology 39 423-430
Kato T and Kitagawa S (2006) Regulation of neutrophil functions by proinflammatory cytokines. International Journal of Hematology 84 205-209
Kato T, Okahashi N, Kawai S, Kato T, Inaba H, Morisaki I and Amano A (2005) Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin. Journal of Periodontology 76 941-950
Kato Jr T, Gotoh Y, Hoffmann A, and Ono Y (2008) Negative regulation of constitutive NF-kB and JNK signaling by PKN1-mediated phosphorylation of TRAF1. Genes Cells 13 509-520
Kato Y, Adachi Y and Ohno N (2006) Contribution of N-linked oligosaccharides to the expression and functions of beta-glucan receptor, dectin-1. Biological &Pharmaceutical Bulletin 29 1580-1586
Kato Y, Ozawa S, Tsukuda M, Kubota E, Miyazaki K, St-Pierre Y and Hata R (2007) Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma. FEBS Journal 274 3171-3183
Kato Y, Ying H, Zhao L, Furuya F, Araki O, Willingham MC and Cheng SY (2006) PPARgamma insufficiency promotes follicular thyroid carcinogenesis via activation of the nuclear factor-kB signaling pathway. Oncogene 25 2736-2747
Kato Y, Ying H, Willingham MC and Cheng SY (2004) A tumor suppressor role for thyroid hormone {beta} receptor in a mouse model of thyroid carcinogenesis. Endocrinology 145 4430-4438
Kataoh M and Katoh M (2007) Notch signaling in gastrointestinal tract. InternationalJournal of Oncology 30 247-251
Katoh M and Katoh M (2007) AP1- and NF-kB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFa-WNT10B signaling loop implicated in carcinogenesis and adipogenesis. International Journal of Molecular Medicine 19 699-703
Kataoka H, Yasuda M, Iyori M, Kura K, Narita M, Nakata T and Shibata K (2006) Roles of N-linked glycans in the recognition of microbial lipopeptides and lipoproteins by TLR2. Cellular Microbiology 8 1199-1209
Kato I, Oya T, Suzuki H, Takasawa K, Ichsan AM, Nadaka S, Ishii T, Shimada Y, Sasahara M, Tobe K, Takasawa S, Okamoto H and Hiraga K (2008) A novel model of insulin-dependent diabetes with renal and retinal lesions by transgenic expression of CaMKIIalpha (Thr286Asp) in pancreatic beta-cells. Diabetes and Metabolism Research Reviews in press
Kato S, Nishio H, Ogura M and Takeuchi K (2007) Tacrolimus (FK506), an immunosuppressive agent, prevents indomethacin-induced small intestinal ulceration in the rat: inhibition of inducible nitric oxide synthase expression. Journal ofPharmacological Sciences in press
Katoh M and Katoh M (2007) AP1- and NF-kB-binding sites conserved among mammalian WNT10B orthologs elucidate the TNFalpha-WNT10B signaling loop implicated in carcinogenesis and adipogenesis. International Journal of Molecular Medicine 19 699-703
Katsel PL and Greenstein RJ (2001) Identification of overlapping AP-2/NF-kB-responsive elements on the rat cholecystokinin gene promoter. Journal of Biological Chemistry 276 752-758
Katsman A, Umezawa K and Bonavida B (2007) Reversal of resistance to cytotoxic cancer therapies: DHMEQ as a chemo-sensitizing and immuno-sensitizing agent. Drug Resistance Updates in press
Katsuyama K, Shichiri M, Kato H, Imai T, Marumo F and Hirata Y (1999) Differential inhibitory actions by glucocorticoid and aspirin on cytokine-induced nitric oxide production in vascular smooth muscle cells. Endocrinology 140 2183-2190
Katsuyama K, Shichiri M, Marumo F and Hirata Y (1998) NO inhibits cytokine-induced iNOS expression and NF-kB activation by interfering with phosphorylation and degradation of IkB-a. Arteriosclerosis, Thrombosis and Vascular Biology 18 1796-1802
Katsuyama K, Shichiri M, Marumo F and Hirata Y (1998) Role of Nuclear Factor-kB activation in cytokine- and sphingomyelinase-stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells. Endocrinology 139 4506-4512
Katula KS, McCain JA and Radewicz AT (2005) Relative ability of dietary compounds to modulate nuclear factor-kappaB activity as assessed in a cell-based reporter system.Journal of Medicinal Food 8 269-274
Katz J, Zhang P, Martin M, Vogel SN and Michalek SM (2006) Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS. Infection andImmunity 74 2809-2816
Katz JA, Itoh J and Fiocchi C (1999) Pathogenesis of inflammatory bowel disease.Current Opinion in Gastroenterology 15 291
Kaufmann JA, Bickford PC and Taglialatela G (2002) Free radical-dependent changes in constitutive Nuclear factor kB in the aged hippocampus. Neuroreport 13 1917-1920
Kaufman PA, Weinberg JB and Greene WC (1992) Nuclear expression of the 50- and 65-kD Rel-related subunits of Nuclear Factor-kB is differentially regulated in human monocytic cells. Journal of Clinical Investigation 90 121-129
Kaufman RJ (1999) Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor. Proceedings of the National Academy of Sciences USA 96 11693-11695
Kaufman RJ (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes & Development 13 1211-1233
Kaul DK, Liu XD, Choong S, Belcher JD, Vercellotti GM and Hebbel RP (2004) Anti-inflammatory therapy ameliorates leukocyte adhesion and microvascular flow abnormalities in transgenic sickle mice. American Journal of Physiology: Heart and Circulatory Physiology 287 H293-H301
Kaul R, Verma SC, Murakami M, Lan K, Choudhuri T and Robertson ES (2006) Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1. Journal of Virology 80 1321-1331
Kaul S, Cercek B, Rengstrom J, Xu XP, Molloy MD, Dimayuga P, Parikh AK, Fishbein MC, Nilsson J, Rajavashisth TB and Shah PK (2000) Polymeric-based perivascular delivery of a nitric oxide donor inhibits intimal thickening after balloon denudation arterial injury: role of nuclear factor-kB. Journal of the American College of Cardiology 35 493-501
Kauppinen TM, Higashi Y, Suh SW, Escartin C, Nagasawa K and Swanson RA (2008) Zinc triggers microglial activation. Journal of Neuroscience 28 5827-5835
Kauppinen TM and Swanson RA (2005) Poly(ADP-Ribose) Polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death.Journal of Immunology 174 2288-2296
Kauppinen TM and Swanson RA (2006) The role of poly(ADP-ribose) polymerase-1 in CNS disease. Neuroscience in press
Kaur H Chen S, Xin X, Chiu J, Khan ZA and Chakrabarti S (2006) Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300. Diabetes 55 3104-3111
Kaur J, Woodman RC, Ostrovsky L and Kubes P (2001) Selective recruitment of neutrophils and lymphocytes by thrombin: a role for NF-kB. American Journal of Physiology: Heart and Circulatory Physiology 281 H784-H795
Kaur M and Agarwal R (2007) Transcription factors: molecular targets for prostate cancer intervention by phytochemicals. Current Cancer Drug Targets 7 355-367
Kaur M Holden NS, Wilson SM, Sukkar MB, Chung KF, Barnes PJ, Newton R and Giembycz MA (2008) Effect of {beta}2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human airways smooth muscle cells: A role for protein kinase A. American Journal of Physiology: Lung Cell and Molecular Physiology in press
Kaur P, Kaur G and Bansal MP (2006) Tertiary-butyl hydroperoxide induced oxidative stress and male reproductive activity in mice: Role of transcription factor NF-kB and testicular antioxidant enzymes. Reproductive Toxicology22 479-484
Kaur S, Wang F, Venkatraman M and Arusra M (2005) X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase1 (JNK1) activation by transforming growth factor-beta 1 (TGF-beta 1) through ubiquitin-mediated proteosomal degradation of the TGF-beta 1-activated kinase1 (TAK1). Journal of Biological Chemistry 280 38599-38608
Kaushal V, Koeberle PD, Wang Y and Schlichter LC (2007) The Ca2+-activated K+ channel KCNN4/KCa3.1 contributes to microglia activation and nitric oxide-dependent neurodegeneration. Journal of Neuroscience 27 234-244
Kaushal V, adn Schlichter LC (2008) Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. Journal of Neuroscience 28 2221-2230
Kavnkova K, Vojtevsek B and Valik D (2001) The Rel/NF-kB transcription factors and their biological functions [Article in Czech]. Cas Lek Cesk 140 163-167
Kavuma MM, Schoppet M, Robryshev YV, Khachigian LM and Bennett MR (2008) TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kB and induction of insulin-like growth factor-1 receptor. Journal of Biological Chemistry 283 7754-7762
Kawabata Y, Furuta S, Shinozaki Y, Kurimoto T and Nishigaki R (2002) Carrier-mediated active transport of a novel thromboxane A(2) receptor antagonist [2-(4-chlorophenylsulfonylaminomethyl)indan-5-yl]acetate (Z- 335) into rat liver. Drug Metab Dispos 30 498-504
Kawada N, Seki S, Kuroki T and Inoue M (1998) Regulation of stellate cell proliferation by lipopolysaccharide: role of endogenous nitric oxide. Journal of Gastroenterology and Hepatology 13 S6-S13
Kawagoe J, Ohmichi M, Takahashi T, Ohshima C, Mabuchi S, Takahashi K, Igarashi H, Mori-Abe A, Saitoh M, Du B, Ohta T, Kimura A, Kyo S, Inoue M and Kurachi H (2003) Raloxifene inhibits estrogen-induced up-regulation of telomerase activity in a human breast cancer cell line. Journal of Biological Chemistry 278 43363-43372
Kawagoe T, Sato S, Jung A, Yamamoto M, Matsui K, Kato H, Uematsu S, Takeuchi O and Akira S (2007) Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor- mediated immune responses but not in TCR signaling. Journal ofExperimental Medicine 204 1013-1024
Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Sitoh T, Kawai T, Takeuchi O and Akira S (2008) Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. Nature Immunology in press
Kawahara T, Kuwano Y, Teshima-Kondo S, Kawai T, Nikawa T, Kishi K and Rokutan K (2001) Toll-like receptor 4 regulates gastric pit cell responses to Helicobacter pylori infection. Journal of Molecular Investigation 48 190-197
Kawahara T, Kuwano Y, Teshima-Kondo S, Takeya R, Sumimoto H, Kishi K, Tsunawaki S, Hirayama T and Rokutan K (2004) Role of nicotinamide adenine dinucleotide phosphate oxidase 1 in oxidative burst response to Toll-like receptor 5 signaling in large intestinal epithelial cells. Journal of Immunology 172 3051-3058
Kawai H, Nie L and Yuan ZM (2002) Inactivation of NF-kB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl. Molecular and Cellular Biology 22 6079-6088
Kawai H, Yamada Y, Tatsuka M, Niwa O, Yamamoto K and Suzuki F (1999) Down-regulation of nuclear factor kB is required for p53-dependent apoptosis in X-ray-irradiated mouse lymphoma cells and thymocytes. Cancer Research 59 6038-6041
Kawai N, Shimada M, Kawahara H, Satoh N and Yokosawa H (2003) Regulation of ascidian Rel by its alternative splice variant. European Journal of Biochemistry 270 4459-4468
Kawai N, Takahashi H, Nishida H and Yokosawa H (2004) Regulation of NF-kB/Rel by IkB is essential for ascidian notochord formation. Developmental Biology 277 80-91
Kawai S, Kataoka T, Sugimoto H, Nakamura A, Kobayashi T, Arao K, Higuchi Y, Ando M and Nagai K (2000) Santonin-related compound 2 inhibits the expression of ICAM-1 in response to IL-1 stimulation by blocking the signaling pathway upstream of IkB degradation. Immunopharmacology 48 129-135
Kawai T and Akira S (2005) Toll-like receptor downstream signaling. Arthritis Research and Therapy 7 12-19
Kawai T and Akira S (2006) TLR signaling. Cell Death and Differentiation 13 816-825
Kawai T and Akira S (2006) Role of IPS-1 in type I IFN induction [Article in Japanese]. Nippon Rinsho 64 1231-1235
Kawai T and AKira S (2007) Signaling to NF-kB by Toll-like receptors. Trends in Molecular Medicine in press
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishitt KJ, Takeuchi O and Akira S (2005) IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nature Immunology 6 981-988
Kawakami A, Aikawa M, Nitta N, Yoshida M, Kibby P and Sacks FM (2006) Apolipoprotein CIII-induced THP-1 cell adhesion to endothelial cells involves Pertussis toxin-sensitive G protein- and protein kinase Ca-mediated nuclear factor-kB activation.Arteriosclerosis, Thrombosis and Vascular Biology 27 219-225
Kawakami A, Nakashima K, Tamai M, Nakamura H, Iwanaga N, Fujikawa K, Aramaki T, Arima K, Iwamoto N, Ichinose K, Kamachi M, Ida H, Origuchi T and Eguchi K (2007) Toll-like receptor in salivary glands from patients with Sjogren’s Syndrome: functional analysis by human salivary gland cell line. Journal of Rheumatology in press
Kawakami H, Tomita M, Matsuda T, Ohta T, Tanaka Y, Fujii M, Hatano M, Tokuhisa T and Mori N (2005) Transcriptional activation of survivin through the NF-kB pathway by human T-cell leukemia virus type I tax. International Journal of Cancer 115 967-974
Kawakami H, Tomita M, Okudaira T, Ishikawa C, Matsuda T, Tanaka Y, Nakazato T, Taira N, Ohshiro K and Mori N (2007) Inhibition of heat shock protein-90 modulates multiple functions required for survival of human T-cell leukemia virus type I-infected T-cell lines and adult T-cell leukemia cells. International Journal of Cancer 120 1811-1820
Kawakita Y, Ikekita M, Kurozumi R and Kojima S (2003) Increase of intracellular glutathione by low-dose gamma-ray irradiation is mediated by transcription factor AP-1 in RAW 264.7 cells. Biol Pharm Bull 26 19-23
Kawakami A, Aikawa M, Alcaide P, Luscinskas FW, Libby P and Sacks FM (2006) Apolipoprotein CIII induces expression of vascular cell adhesion molecule-1 in vascular endothelial cells and increases adhesion of monocytic cells. Circulation114 681-687
Kawakami A and Eguchi K (2002) Involvement of apoptotic cell death in autoimmune diseases. Medical Electron Microscopy 35 1-8
Kawakami A, Nakashima T, Sakai H, Urayama S, Yamasaki S, Hida A, Tsuboi M, Nakamura H, Ida H, Migita K, Kawabe Y and Eguchi K (1999) Inhibition of caspase cascade by HTLV-I tax through induction of NF-kB nuclear translocation. Blood 94 3847-3854
Kawakami K, Scheidereit C and Roeder RG (1988) Identification and purification of the human immunoglobulin-enhancer binding protein (NF-kB) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proceedings of the National Academy of Sciences USA 85 4700-4704
Kawakami S, Ito Y, Charoensit P, Yamasnita F and Hashida M (2006) Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice. Journal of Pharmacology andExperimental Therapeutics 317 1382-1390
Kawamoto T, Ii M, Kitazaki T, Iizawa Y and Kimura H (2008) TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain. European Journal of Immunology in press
Kawamura A, Baitsch D, Telgmann R, Feuerborn R, Weissen-Plenz G, Hagedorn C, Saku K, Brand-Herrmann SM, von Eckardstein A, Assmann G and Nofer JR (2007) Apolipoprotein E interrupts interleukin-1beta signaling in vascular smooth muscle cells.Arteriosclerosis, Thrombosis, and Vascular Biology 27 1610-1617
Kawamura N, Dyck PJ, Schmeichel AM, Engelstad JK, Low PA and Dyck PJ (2007) Inflammatory mediators in diabetic and non-diabetic lumbosacral radiculoplexus neuropathy. Acta Neuropatholica in press
Kawamura N, Kugimiya F, Oshima Y, Ohba S, Ikeda T, Saito T, Sinoda Y, Kawasaki Y, Ogata N, Hoshi K, Akiyama T, Chen WS, Hay N, Tobe K, Kadowaki T, Azuma Y, Tanaka S, Nakamura K, Chung UI and Kawaguchi H (2007) Akt1 in osteoblasts and osteoclasts controls bone remodeling. PLoS ONE 2 e1058
Kawamura N, Schmeichel AM, Wang Y, Schmelzer JD and Low PA (2006) Multiple effects of hypothermia on inflammatory response following ischemia-reperfusion injury in experimental ischemic neuropathy. Experimental Neurology 202 487-496
Kawakita T, Shiraki K, Yamanaka Y, Yamaguchi Y, Saitou Y, Enokimura N, Yamamoto N, Okano H, Sugimoto K, Murata K and Nakano T (2004) Functional expression of TWEAK in human hepatocellular carcinoma: possible implication in cell proliferation and tumor angiogenesis. Biochemical and Biophysical Research Communications 318 726-733
Kawakita T, Shiraki K, Yamanaka Y, Yamaguchi Y, Saitou Y, Enokimura N, Yamamoto N, Okano H, Sugimoto K, Murata K and Nakano T (2005) Functional expression of TWEAK in human colonic adenocarcinoma cells. International Journal of Oncology 26 87-93
Kawakubo H, Carey JL, Brachtel E, Gupta V, Green JE, Walden PD and Maheswaran S (2004) Expression of the NF-kB-responsive gene BTG2 is aberrantly regulated in breast cancer. Oncogene 23 8310-8319
Kawamata S, Hori T, Imura A, Takaori-Kondo A and Uchiyama T (1998) Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2 and TRAF5-mediated NF-kB activation. Journal of Biological Chemistry 273 5808-5814
Kawamoto EM, Lepsch LB, Boaventura MF, Munhoz CD, Lima LS, Yshii LM, Avellar MC, Curi R, Mattson MP and Scavone C (2007) Amyloid beta-peptide activates nuclear factor-kB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells. Journal of Neuroscience Research in press
Kawana H, Karaki H, Higasti M, Miyazaki M, Hilberg F, Kitagawa M and Harigaya K (2008) CD44 suppresses TLR-mediated inflammation. Journal of Immunology 180 4235-4245
Kawaoka S, Katusuma S, Daimon T, Isono R, Omuro N, Mita K and Shimada T (2007)Functional analysis of four Gloverin-like genes in the silkworm, Bombyx mori. Archives of Insect Biochemistry and Physiology in press
Kawauchi K, Tobiume K, Kaneko S, Kaneshiro K, Okamoto S, Ueda E, Kamata H, Moriyama Y and Hirato H (2007) Suppression of AP-1 activity by cycloprodigiosin hydrochloride. Biol Pharm Bull 30 1792-1795
Kawamura H, Wakabayshi T, Yamaguchi S, Taniguchi T, Takayanagi N, Sato S, Sekiya S and Horiuchi T (1976) Incoulation experiment of Marek’s disease vaccine contaminated with reticuloendotheliosis virus. National Institute of Animal Health Quarterly 16 135-140
Kawamura I, Morishita R, Tomita N, Lacey E, Aketa M, Tsujimoto S, Manda T, Tomoi M, Kida I, Higaki J, Kaneda Y, Shimomura K and Ogihara T (1999) Intratumoral injection of oligonucleotides to the NF kB binding site inhibits cachexia in a mouse tumor model. Gene Therapy 6 91-97
Kawamura I, Morishita R, Tsujimoto S, Manda T, Tomoi M, Tomita N, Goto T, Ogihara T and Kaneda Y (2001) Intravenous injection of oligodeoxynucleotides to the NF-kB binding site inhibits hepatic metastasis of M5076 reticulosarcoma in mice. Gene Therapy 8 905-912
Kawamura M, Kasai H, He L, Deng X, Yamashita A, Terunuma H, Horiuchi I, Tanabe F and Ito M (2005) Antithetical effects of hemicellulase-treated Agaricus blazei on the maturation of murine bone-marrow-derived dendritic cells. Immunology 114 397-409
Kawamura N, Kubota T, Kawano S, Monden Y, Feldman AM, Tsutsui H, Takeshita A and Sunagawa K (2005) Blockade of NF-kB improves cardiac function and survival without affecting inflammation in TNF-a-induced cardiomyopathy. Cardiovascular Research 66 520-529
Kawamura T, Kadosaki M, Nara N, Wei J, Endo S and Inada K (2005) Nicorandil attenuates NF-kB activation, adhesion molecule expression, and cytokine artery bypass surgery. Shock 24 103-108
Kawamura YI, Kawashima R, Shirai Y, Kato R, Hamabata T, Yamamoto M, Furukawa K, Fujihashi K, McGhee JR, Hayashi H and Dohi T (2003) Cholera toxin activates dendritic cells through dependence on GM1-ganglioside which is mediated by NF-kB translocation. European Journal of Immunology 33 3205-3212
Kawanami D, Maemura K, Takeda N, Harada T, Jojiri T, Saito T, Manabe I, Imai Y and Nagai R (2005) C-reactive protein induces VCAM-1 gene expression through NF-kB activation in vascular endothelial cells. Atherosclerosis 185 39-46
Kawano S, Kubota T, Monden Y, Kawamura N, Tsutsui H, Takeshita A and Sunagawa K (2005) Blockade of NF-kB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II. Cardiovascular Research 67 689-698
Kawano S, Kubota T, Monden Y, Tsutsumi T, Inoue T, Kawamura N, Tsutsui H and Sunagawa K (2006) Blockade of NF-kB improves cardiac function and survival after myocardial infarction. American Journal of Physiology: Heart and CirculatoryPhysiology in press
Kawano T, Ahmad R, Nogi H, Agata N, Anderson K and Kufe D (2008) MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells. International Journal of Oncology 33 153-159
Kawano T, Matsuse H, Kondo Y, Machida I, Saeki S, Tomari S, Mitsuta K, Obase Y, Fukushima C, Shimoda T and Kohno S (2003) Cysteinyl leukotrienes induce nuclear factor kb activation and rantes production in a murine model of asthma. Journal of Allergy and Clinical Immunology 112 369-374
Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K and Nishijima M (2000) Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol. Journal of Biological Chemistry 275 2251-2254
Kawasaki K, Ernst RK and Miller SI (2004) 3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through toll-like receptor 4. Journal of Biological Chemistry 279 20044-20448
Kawashima S, Hayashi M, Takii T, Kimura H, Zhang HL, Nagatsu A, Sakakibara J, Murata K, Oomoto Y and Onozaki K (1998) Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-a, IL-1a, IL-1b, and IL-6 by endotoxin-stimulated human blood monocytes. Journal of Interferon and Cytokine Research 18 423-428
Kawashima T, Murata K, Akira S, Tonozuka Y, Minoshima Y, Feng S, Kumagai H, Tsuruga H, Ikeda Y, Asano S, Nosaka T and Kitamura T (2001) STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kB p65. Journal of Immunology 167 3652-3660
Kawata S, Ariumi Y and Shimotohno K (2003) p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded Tax. Journal of Virology 77 7291-7299
Kawauchi K, Araki K, Tobiume K and Tanaka N (2008) p53 regulates glucose metabolism through an IKK-NF-kB pathway and inhibits cell transformation. Nature Cell Biology in press
Kawauchi K, Araki K, Tobiume K and Tanaka N (2008) Activated p53 induces NF-kB DNA binding but suppresses its transcriptional activation. Biochemical and Biophsyical Research Communications in press
Kayal S, Lilienbaum A, Join-Lambert O, Li X, Israel A and Berche P (2002) Listeriolysin O secreted by Listeria monocytogenes induces NF-kB signalling by activating the IkB kinase complex. Molecular Microbiology 44 1407-1419
Kayal S, Lilienbaum A, Poyart C, Memet S, Israel A and Berche P (1999) Listeriolysin O-dependent activation of endothelial cells during infection with Listeria monocytogenes: activation of NF-kB and upregulation of adhesion molecules and chemokines. Molecular Microbiology 31 1709-1722
Kayama H, Ramirez-Carrozzi VR, Yamamoto M, Mintani T, Kuwata H, Iba H, Matsumoto M, Honda K, SMale ST and Takeda K (2008) Class-specific regulation of pro-inflammatory genes by MYD88 pathways and IkBzeta. Journal of Biological Chemistry 283 12468-12477
Kaye KM, Izumi KM, Li H, Johannsen E, Davidson D, Longnecker R and Kieff E (1999) An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformation. Journal of Virology 73 10525-10530
Kaykas A, Worringer K and Sugden B (2002) LMP-1’s transmembrane domains encode multiple functions required for LMP-1’s efficient signaling. Journal of Virology 76 11551-11560
Kazama S, Ajioka Y, Watanabe H, Watanabe T and Nagawa H (2002) Histogenesis and morphogenesis of depressed-type early colorectal carcinoma. Pathology International 52 119-125
Kazi A, Daniel KG, Smith DM, Kumar NB and Dou QP (2003) Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Biochemical Pharmacology 66 965-976
Kazi A, Wang Z, Kumar N, Falsetti SC, Chan TH and Dou QP (2004) Structure-activity relationships of synthetic analogs of (-)-epigallocatechin-3-gallate as proteasome inhibitors. Anticancer Research 24 943-954
Kazmi S, Plante R, Visconte V, Taylor GR, Zhou L and Lau CY (1995) Suppression of NFkB-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase. Journal of Cellular Biochemistry 57 299-310
Kazzaz JA, Horowitz S, Li Y and Mantell LL (1999) Hyperoxia in cell culture. A non-apoptotic programmed cell death. Annals of the New York Academy of Sciences 887 164-170
Ke B, Shen XD, Tsuchihashi SI, Gao F, Araujo JA, Busuttil RW, Ritter T and Kupiec-Weglinski JW (2007) Viral interleukin-10 gene transfer prevents liver ischemia-reperfusion injury: Toll-like receptor-4 and heme oxygenase-1 signaling in innate and adaptive immunity. Human Gene Therapy in press
Ke J, Long X, Liu Y, ZXhang YF, Li J, Fang W and Meng QG (2007) Role of NF-kB in TNF-alpha-induced COX-2 expression in synovial fibroblasts from human TMJ. Journal of Dental Research 86 363-367
Ke JJ, Wang YL, Li JG, Wu J and Feng XB (2004) Pretreatment effect of adenosine on activation of NF-kB and level of TNF-alpha during myocardial ischemia and reperfusion in rats. Chinese Journal of Traumatology 7 25-27
Ke XY, Gribben J, Wang J and Wang DB (2002) The Identical Effects of B7-1 and B7-2 on regulation of human IL-2 gene transcription factors NF-kB and AP-1 [Article in Chinese]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 10 512-518
Kean WF (2004) Oxaprozin: kinetic and dynamic profile in the treatment of pain. Current Medical Research Opinion 20 1275-1277
Keane CJ, Hanlon AJ, Roche JF, Burton JL, Mee JF, O’Doherty JV and Sweeney T (2006) A potential antiapoptotic phenotype in neutrophils of cows milked once daily in early lactation. Journal of Dairy Science in press
Keane MM, Rubinstein Y, Cuello M, Ettenberg SA, Banerjee P, Nau MM and Lipkowitz S (2001) Inhibition of NF-kB activity enhances TRAIL mediated apoptosis in breast cancer cell lines. Breast Cancer Research and Treatment 64 211-219
Kearns JD, Basak S, Werner SL, Huang CS and Hoffmann A (2006) IkBepsilon provides negative feedback to control NF-kB oscillations, signaling dynamics, and inflammatory gene expression. Journal of Experimental Medicine 203 in press
Keates S, Keates AC, Warny M, Peek RM, Jr., Murray PG and Kelly CP (1999) Differential activation of mitogen-activated protein kinases in AGS gastric epithelial cells by cag+ and cag- Helicobacter pylori. Journal of Immunology 163 5552-5559
Keating SE, Maloney GM, Moran EM and Bowie AG (2007) IRAK-2 participates in multiple Toll-like receptor signaling pathways to NFkB via activation of TRAF6 ubiquitination. Journal of Biological Chemistry 282 33435-33443
Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX, Fogle H, Price-Troska T, Ahmann G, Mancini C, Brents LA, Kumar S, Greipp P, Dispenzieri A, Bryant B, Julligan G, Bruhn L, Barrett M, Valdez R, Trent J, Stewart AK, Carpten J and Bergsagel PL (2007) Promiscuous mutations activate the noncanonical NF-kB pathway in multiple myeloma.Cancer Cell 12 131-144
Kedar PS, Arden K, Foyle M, Pope JH and Zeichner SL (2002) Umbilical cord blood mononuclear cell HIV-1 LTR binding activities. Journal of Biomedical Sciences 4 217-222
Keel M, Mica L, Stover J, Stocker R, Trentz O and Harter L (2005) Thiopental-induced apoptosis in lymphocytes is independent of CD95 activation. Anesthesiology 103 576-584
Keestra AM, de Zoete MR, van Aubel RA and van Putten JP (2007) The central leucine-rich repeat region of chicken TLR16 dictates unique ligand specificity and species-specific interaction with TLR2. Journal of Immunology 178 7110-7719
Keestra AM, de Zoete MR, van Aubel RA and van Putten JP (2007) Functional characterization of chicken TLR5 reveals species-specific recognition of flagellin.Molecular Immunology in press
Kefaloyianni E, Gaitanaki C and Beis I (2006) ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-kB transactivation during oxidative stress in skeletal myoblasts. Cellular Signaling 18 2238-2251
Kefer J, Rahman A, Anwar KN and Malik AB (2001) Decreased oxidant buffering impairs NF-kB activation and ICAM-1 transcription in endothelial cells. Shock 15 11-15
Kehry MR (1996) CD-40-mediated signaling in B cells. Balancing cell survival, growth, and death. Journal of Immunology 156 2345-2348
Keicho N, Higashimoto Y, Bondy GP, Elliott WM, Hogg JC and Hayashi S (1999) Endotoxin-specific NF-kB activation in pulmonary epithelial cells harboring adenovirus E1A. American Journal of Physiology 277 L523-L532
Keifer JA, Guttridge DC, Ashburner BP and Baldwin AS Jr (2001) Inhibition of NF-kB activity by thalidomide through suppression of IkB kinase activity. Journal of Biological Chemistry 276 22382-22387
Keightley AM, Lam YM, Brady JN, Cameron CL and Lillicrap D (1999) Variation at the von Willebrand factor (vWF) gene locus is associated with plasma vWF:Ag levels: identification of three novel single nucleotide polymorphisms in the vWF gene promoter. Blood 93 4277-4283
Keiss HP, Dirsch VM, Hartung T, Haffner T, Trueman L, Auger J, Kahane R and Vollmar AM (2003) Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kB activity. Journal of Nutrition 133 2171-2175
Keith Jr JC, Albert LM, Leathurby Y, Follettie M, Wang L, Borges-Marcucci L, Chadwick CC, Steffan RJ and Harnish DC (2005) The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kB transcriptional activity in models of rheumatoid arthritis. Arthritis Research and Therapy 7 R427-R438
Kekuda R, Leibach FH, Furesz TC, Smith CH and Ganapathy V (2000) Polarized distribution of interleukin-1 receptors and their role in regulation of serotonin transporter in placenta. J Pharmacol Exp Ther 292 1032-1041
Kékule AS, Lauer U, Weiss L, Luber B and Hofschneider PH (1993) Hepatitis B virus transactivator HBx uses a tumor promoter signalling pathway. Nature 361 742-745
Kelleher ZT, Matsumoto A, Stamler JS and Marshall HE (2007) NOS2 regulation of NF-kB by S-nitrosylation of p65. Journal of Biological Chemistry 282 40667-30672
Keller ET (2004) Metastasis suppressor genes: a role for raf kinase inhibitor protein (RKIP). Anticancer Drugs 15 663-669
Keller ET, Fu Z and Brennan M (2004) The biology of a prostate cancer metastasis suppressor protein: Raf kinase inhibitor protein. J Cell Biochem 94 273-278
Keller ET, Fu Z, Yeung K and Brennan M (2004) Raf kinase inhibitor protein: a prostate cancer metastasis suppressor gene. Cancer Letters 207 131-137
Keller LH, Rutner R and Sevoian M (1979) Isolation and development of a reticuloendotheliosis virus-transformed lymphoblastoid cell line from chicken spleen cells. Infection & Immunity 25 694-701
Keller SA, Hernandez-Hopkins D, Vider J, Pnomarev V, Hyjek E, Schattner EJ and Cesarman E (2005) NF-kB is essential for progression of KSHV- and EBV-infected lymphomas in vivo. Blood in press
Keller SH, Platoshyn O and Yuan JX (2005) Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways. Cell Biochem Biophys 43 365-378
Keller U, Nilsson JA, Maclean KH, Old JB and Cleveland JL (2005) Nfkb1 is dispensable for Myc-induced lymphomagenesis. Oncogene 24 6231-6240
Kellum JA, Song M and Almasri E (2006) Hyperchloremic acidosis increases circulating inflammatory molecules in experimental sepsis. Chest 130 962-967
Kellum JA, Song M and Li J (2003) Lactic, and hydrochloric acids induce different patterns of inflammatory response in LPS-stimulated RAW 264.7 cells. American Journal of Physiology: Regulotry, Integrative and Comparative Physiology 286 R686-R692
Kellum JA, Song M and Venkataraman R (2004) Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-kappaB DNA binding, and improves short-term survival in lethal endotoxemia. Critical Care Medicine 32 801-805
Kelly A, Vereker E, Nolan Y, Brady M, Barry C, Loscher CE, Mills KH and Lynch MA (2003) Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1beta on long-term potentiation in rat dentate gyrus. Journal of Biological Chemistry 278 19453-19462
Kelly D, Campbell JI, King TP, Grant G, Jansson EA, Coutts AG, Pettersson S and Conway S (2003) Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nature Immunology 5 104-112
Kelly D, Conway SBacterial modulation of mucosal innate immunity. Molecular Immunology 42 895-901
Kelly GD, Morris CB and Offermann MK (1999) Lack of responsiveness of a nuclear factor-kB-regulated promoter to transactivation by human immunodeficiency virus 1 Tat in HeLa cells. Virology 263 128-138
Kelly JM, Moir AJ, Carlson K, Yang Y, Macneil S and Haycock JM (2005) Immobilized alpha-melanocyte stimulating hormone 10-13 (GKPV) inhibits tumor necrosis factor-a stimulated NF-kB activity. Peptides 27 431-437
Kelly KA, Hill MR, Youkhana K, Wanker F and Gimble JM (1994) Dimethyl sulfoxide modulates NF-kB and cytokine activation in lipopolysaccharide-treated murine macrophages. Infection & Immunity 62 3122-3128
Kelschenbach J, Ninkovic J, Wang J, Krishnan A, Charboneau R, Barke RA and Roy S (2008) Morphine withdrawal inhibits IL-12 induction in a macrophage cell line through a mechanism that involves cAMP. Journal of Immunology 180 3670-3679
Kemler I and Fontana A (1999) Role of IkappaBalpha and IkBb in the biphasic nuclear translocation of NF-kB in TNFa-stimulated astrocytes and in neuroblastoma cells. Glia 26 212-220
Kempe S, Kestler H, Lasar A and Wirth T (2005) NF-kB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program. Nucleic Acids Research 33 5308-5319
Kempf VA, Schairer A, Neumann D, Grassl GA, Lauber K, Lebiedziejewski M, Schaller M, Kyme P, Wesselborg S, Autenrieth IB (2005) Bartonella henselae inhibits apoptosis in Mono Mac 6 cells. Cellular Microbiology 7 91-104
Kempiak SJ, Hiura TS and Nel AE (1999) The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: proof of cross-talk with the IkB kinase cascade. Journal of Immunology 162 3176-3187
Kempuraj D, Huang M, Kandere-Grzybowska K, Basu S, Boucher W, Letourneau R, Athanassiou A and Theoharides TC (2003) Azelastine inhibits secretion of IL-6, TNF-a and IL-8 as well as NF-kB activation and intracellular calcium ion levels in normal human mast cells. International Archives of Allergy and Immunology 132 231-239
Kennedy JC, Memet S and Wells PG (2004) Antisense evidence for nuclear factor-kB-dependent embryopathies initiated by phenytoin-enhanced oxidative stress. Molecular Pharmacology 66 404-412
Kennedy MW, Green KA, Ford RL, Andrews PG, Paterno GD, Gillespie LL and Kao KR (2007) Regulation of the response to Nodal-mediated mesoderm induction by Xrel3.Develpmental Biology in press
Kennedy T, Shio AJ, Reed W, Samet J, Zagorski J, Quay J, Carter J, Dailey L, Hoidal JR and Devlin RB (1998) Copper-dependent inflammation and Nuclear Factor-kB activation by particulate air pollution. American Journal of Respiratory Cell and Molecular Biology 19 366-378
Kent L, Smyth L, Clayton C, Scott L, Cook T, Stephens R, Fox S, Hext P, Farrow S and Singh D (2008) Cigarette smoke extract induced cytokine and chemokine gene expression changes in COPD macrophages. Cytokine inpress
Kenter AL, Wuerffel R, Dominguez C, Shanmugam A and Zhang H (2004) Mapping of a functional recombination motif that defines isotype specificity for {micro}->{gamma}3 switch recombination implicates NF-kB p50 as the isotype-specific switching factor. Journal of Experimental Medicine 199 617-627
Kenter AL, Wuerffel R, Sen R, Jamieson CE and Merkulov GV (1993) Switch recombination breakpoints occur at nonrandom positions in the Sg tandem repeat. Journal of Immunology 151 4718-4731
Kenwrick S (2002) Incontinentia pigmenti: the first single gene disorder due to disrupted NF-kB function. Ernst Schering Research Foundation Workshop 36 95-107
Kenwrick S and The International IP Consortium (2001) Survival of male patients with incontinentia pigmenti carrying a lethal mutation can be explained by somatic mosaicism or Klinefelter syndrome. American Journal of Human Genetics 69 1210-1217
Kenzel S, Mancuso G, Malley R, Teti G, Golenbock DT andHenneke P (2006) c-Jun kinase is a critical signaling molecule in a neonatal model of group B Streptococcal sepsis. Journal of Immunology 176 3181-3188
Kerbauy DB and Deeg HJ (2007) Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome. Experimental Hematology 35 1739-1746
Kerbauy DM, Lesnikov V, Abbasi N, Seal S, Scott B and Deeg HJ (2005) NF-kB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDS). Blood 106 3917-3925
Kerecman J, Mustafa SB, Vasquez MM, Dixon PS and Castro R (2008) Immunosuppressive properties of surfactant in alveolar macrophage NR8383. Inflammation Research 57 118-125
Kern C, Cornuel JF, Billard C, Tang R, Rouillard D, Steunou V, Defrance T, Ajchenbaum-Cymbalista F, Simonin PY, Feldblum S and Kolb JP (2003) Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway. Blood 103 679-688
Kern JC and Kehrer JP (2005) Free radicals and apoptosis: relationships with glutathione, thioredoxin, and the BCL family of proteins. Frontiers in Bioscience 10 1727-1738
Kern TS (2007) Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Experimental Diabetes Research 2007 95013
Kerr BJ, Girolami EI, Ghasemlou N, Jeong SY and David S (2008) The protective effects of 15-deoxy-Delta-(12,14)-prostaglandin J(2) in spinal cord injury. Glia 56 436-448
Kerr C (2002) Curry ingredient protects skin against radiation. Lancet Oncology 3 713
Kerr L (1992) Hot papers – Molecular Biology – The Rel-associated pp40 protein prevents DNA binding of Rel and NF-kB: relationship with IkBb and regulation by phosphorylation by Kerr LD, Inoue JI, Davis N, Link E et al. Scientist 6 15
Kerr LD and Verma IM (1992) cRel and NFkB cooperate to regulate cellular proliferation in B lymphocytes. Journal of Cellular Biochemistry Supplement 16B 225
Kerr LD, Duckett CS, Wamsley P, Zhang Q, Chiao P, Nabel G, McKeithan TW, Baeuerle PA and Verma IM (1992) The proto-oncogene BCL-3 encodes an IkB protein. Genes & Development 6 2352-2363
Kerr LD, Inoue J-I, Davis N, Link E, Baeuerle PA, Bose Jr HR and Verma IM (1991) The Rel-associated pp40 protein prevents DNA binding of Rel and NF-kB: relationship with IkBb and regulation by phosphorylation. Genes & Development 5 1464-1476
Kerr LD, Ransone LJ, Wamsley P, Schmitt MJ, Boyer TG, Zhou Q, Berk AJ and Verma IM (1993) Association between proto-oncoprotein Rel and TATA-binding protein mediates activation by NF-kB. Nature 365 412-419
Kerry S, Tekippe M, Gaddis NC and Aballay A (2006) GATA transcription factor required for immunity to bacterial and fungal pathogens. PLoS ONE 1 e77
Kerschan-Schindl K, Wendlova J, Kudlacek S, Gleiss A, Woloszczuk W and Peitschmann P (2007) Serum levels of receptor activator of nuclear factor kB ligand (RANKL) in healthy women and men. Experimental and Clinical Endocrinology and Diabetes in press
Kersse K, Berghe TV, Lamkanfi M and Vandenabeele P (2007) A phylogenetic and functional overview of inflammatory caspases and caspase-1-related CARD-only proteins. Biochemical Society Transactions 35 1508-1511
Kerstan A and Hunig T (2004) Distinct TCR- and CD28-derived signals regulate CD95L, Bcl-x(L), and the survival of primary T cells. Journal of Immunology 172 1341-1345
Kerzic PJ, Pyatt DW, Zheng JH, Gross SA, Le A and Irons RD (2003) Inhibition of NF-kB by hydroquinone sensitizes human bone marrow progenitor cells to TNF-alpha-induced apoptosis. Toxicology 187 127-137
Keshamouni VG, Arenberg DA, Reddy RC, Newstead MJ, Anthwal S and Standiford TJ (2005) PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer. Neoplasia 7 294-301
Keslacy S, Tliba O, Baidouri H and Amrani Y (2006) Inhibition of TNFa-inducible inflammatory genes by IFNg is associated with altered NF-kB transactivation and enhanced HDAC activity. Molecular Pharmacology in press
Kessel A, Bishara R, Amital A, Bamberger E, Sabo E, Grushko G and Toubi E (2005) Increased plasma levels of matrix metalloproteinase-9 are associated with the severity of chronic urticaria. Clinical and Experimental Allergy 35 221-225
Kessel A, Rosner I, Rozenbaum M, Zisman D, Sagiv A, Shmuel Z, Sabo E and Toubi E (2004) Increased CD8+ T cell apoptosis in scleroderma is associated with low levels of NF-kB. Journal of Clinical Immunology 24 30-36
Kessler DJ, Duyao MP, Spicer DB and Sonenshein GE (1992) NF-kB-like factors mediate interleukin 1 induction of c-myc gene transcription in fibroblasts. Journal of Experimental Medicine 176 787-792
Kessler DJ, Spicer DB, La Rosa FA and Sonenshein GE (1992) A novel NF-kB element within exon 1 of the murine c-myc gene. Oncogene 7 2447-2453
Kesson AM and King NJ (2001) Transcriptional regulation of major histocompatibility complex class I by flavivirus West Nile is dependent on NF-kB activation. Journal of Infectious Diseases 184 947-954
Kettritz R, Choi M, Rolle S, Wellner M and Luft FC (2004) Integrins and cytokines activate NF-kB in human neutrophils. Journal of Biological Chemistry 279 2657-2665
Kettritz R, Choi M, Salanova B, Wellner M, Rolle S and Luft FC (2006) Fever-like temperatures affect neutrophil NF-kB signaling, apoptosis, and ANCA-antigen expression. Journal of the American Society of Nephrology in press
Keulen JK, Timmers L, van Kuijk LP, Retnam L, Hoefer IE, Pasterkamp G, Lim SK and de Kleijn DP (2008) The nuclear factor-kB p50 subunit is involved in flow-induced outward arterial remodeling. Atherosclerosis in press
Keum YS, Han SS, Chun KS, Park KK, Park JH, Lee SK, Surh YJ (2003) Inhibitory effects of the ginsenoside Rg(3) on phorbol ester-induced cyclooxygenase-2 expression, NF-kB activation and tumor promotion. Mutation Research 523-524 75-85
Keum YS, Jeong WS and Kong AN (2004) Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms. Mutation Research 555 191-202
Keum YS, Jeong WS and Kong AN (2005) Chemopreventive functions of isothiocyanates.Drug News Perspect 18 445-452
Keutgens A, Robert I, Viatour P and Chariot A (2006) Deregulated NF-kB activity in haematological malignancies. Biochemical Pharmacology 72 1069-1080
Kfoury Y, Nasr R, Favre-Bonvin A, El-Sabban M, Renault N, Gifron ML, Setterblad N, Hajj HE, Chiari E, Mikati AG, Hermine O, Saib A, de The H, PIque C and Bazarabachi A (2007) Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome.Oncogene in press
Kfoury Y, Nasr R, Hermine O, de The H and Bazarbachi A (2005) Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kB pathway. Cell Death and Differentiation 12 871-877
Khadaroo RG, He R, Parodo J, Powers KA, Marshall JC, Kapus A and Rotstein OD (2004) The role of the Src family of tyrosine kinases after oxidant-induced lung injury in vivo. Surgery 136 483-488
Khadaroo RG, Kapus A, Powers KA, Cybulsky MI, Marshall JC and Rotstein OD (2003) Oxidative stress reprograms LPS signaling via Src kinase-dependent pathway in RAW 264.7 macrophage cell line. Journal of Biological Chemistry 278 47834-47841
Khadaroo RG, Parodo J, Powers KA, Papia G, Marshall JC, Kapus A and Rotstein OD (2003) Oxidant-induced priming of the macrophage involves activation of p38 mitogen-activated protein kinase through an Src-dependent pathway. Surgery 134 242-246
Khadeer MA, Sahu SN, Bai G, Abdulla S and Gupta A (2005) Expression of the zinc transporter ZIP1 in osteoclasts. Bone 37 296-304
Khaled AR, Butfiloski EJ, Sobel ES and Schiffenbauer J (1998) Functional consequences of the SHP-1 defect in motheaten viable mice: role of NF-kB. Cellular Immunology 185 49-58
Khaled AR, Butfiloski EJ, Villas B, Sobel ES and Schiffenbauer J (1999) Aberrant expression of the NF-kB and IkB proteins in B cells from viable motheaten mice. Autoimmunity 30 115-128
Khaled Z, Benimetskaya L, Zeltser R, Khan T, Sharma HW, Narayanan R and Stein CA (1996) Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides. Nucleic Acids Research 24 737-745
Khan AA, Martin S adn Saha B (2008) SEB-induced signaling in macrophages leads to biphasic TNF-a. Journal of Leukocyte Biology in press
Khan E and Abu-Amer Y (2003) Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts. Lab Clin Med 142 29-34
Khan G (2006) Epstein-Barr virus, cytokines, and inflammation: A cocktail for the pathogenesis of Hodgkin’s lymphoma? Experimental Hematology 34 399-406
Khan M, Sekhon B, Giri S, Jatana M, Gilg AG, Ayasolla K, Elango C, Singh AK and Singh I (2005) S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke. Journal of Cerebral Blood Flow and Metabolism 25 177-192
Khan MA, Kang J and Steiner TS (2004) Enteroaggregative Escherichia coli flagellin-induced interleukin-8 secretion requires Toll-like receptor 5-dependent p38 MAP kinase activation. Immunology 112 651-660
Khan MA, Ma C, Knodler LA, Valdez Y, Rosenberger CM, Deng W, Finaly BB and Vallance BA (2006) Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice. Infection and Immunity 74 2522-2536
Khan MN and Khan AA (2008) Cancer treatment-related bone loss: a review and synthesis of the literature. Current Oncology 15 S30-S40
Khan MZ, Brandimarti R, Patel JP, Huynh N, Wang J, Huang Z, Fatatis A and Meucci O (2004) Apoptotic and antiapoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis. AIDS Research and Human Retroviruses 20 1063-1071
Khan N, Alam K, Mande SC, Valluri VL, Hasnain SE and Mukhopadhyay S (2008) Mycobacterium tuberculosis heat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages. Cellular Microbiology in press
Khan N, Ghousunnissa S, Jegadeeswaran SM, Thiagarajan D, Hasnain SE and Mukhopadhyay S (2007) Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kB-dependent pathway. International Immunology 19 477-486
Khan N, Hadi N, Afaq F, Syed DN, Kweon MH and Mukhtar H (2006) Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice. Carcinogenesis in press
Khan N, Rahim SS, Boddupalli CS, Ghousunnissa S, Padma S, Pathak N, Thiagarajan D, Hasnain SE and Mukhopadhyay S (2006) Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-Rel translocation to the nucleus through activation of calmodulin protein. Blood 107 1513-1520
Khan SA, Lopez-Chua CA, Zhang J, Fisher LW, Sorensen ES and Denhardt DT (2002) Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors. Journal of Cellular Biochemistry 85 728-736
Khan ZA and Chakrabarti S (2007) Cellular signaling and potential new treatment targets in diabetic retinopathy. Experimental Diabetes Research 2007 31867
Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL and McConkey DJ (2006) Nuclear factor-kB maintains TRAIL resistance in human pancreatic cancer cells. Molecular Cancer Therapy 5 2251-2260
Khanna AK, Plummer M, Nilakantan V and Pieper GM (2005) Recombinant p21 protein inhibits lymphocyte proliferation and transcription factors. Journal of Immunology174 7610-7617
Khanna D, Sethi G, Ahn KS, Pandey MK, Kunnamakkara AB, Sung B, Aggarwal A and Aggarwal BB (2007) Natural products as a gold mine for arthritis treatment. CurrentOpinion in Pharmacology in press
Khanna N, Sen S, Sharma H and Singh N (2003) S29 ribosomal protein induces apoptosis in H520 cells and sensitizes them to chemotherapy. Biochemical and Biophysical Research Communications 304 26-35
Khapli SM, Mangashetti LS, Yogesha SD and Wani MR (2003) IL-3 acts directly on osteoclast precursors and irreversibly inhibits receptor activator of NF-kB ligand-induced osteoclast differentiation by diverting the cells to macrophage lineage. Journal of Immunology 171 142-151
Kharroubi AE, Piras G, Zensen R and Martin MA (1998) Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. Molecular and Cellular Biology 18 2535-2544
Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M and Eizirik DL (2004) Free fatty acids and cytokines induce pancreatic b-cell apoptosis by different mechanisms: role of NF-kB and endoplasmic reticulum stress. Endocrinology 145 5087-5096
Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL and Cnop M (2006)BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. Diabetologia 49 2350-2358
Khatri M and Sharma JM (2006) Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kB pathways. Virus Research 118 70-77
Khayrullina T, Yen JH, Jing H and Ganea D (2008) In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. Journal of Immunology 181 721-735
Khera T, Martin J, Riley S, Steadman R and Phillips AO (2007) Glucose enhances mesangial cell apoptosis. Laboratory Investigation 87 690-701
Kheradmand F, Werner E, Tremble P, Symons M and Werb Z (1998) Role of Rac-1 and oxygen radicals in collagenase-1 expression induced by cell shape change. Science 280 898-902
Khil LY, Kim W, Lyu S, Park WB, Yoon JW and Jun HS (2007) Mechanisms involved in Korean mistletoe lectin-induced apopotsos of cancer cells. World Journal of Gastroenterology 13 2811-2818
Khong T, Sharkey J and Spencer A (2008) The effect of azacitidine on interleukin-6 signaling and nuclear factor-kB activation and its in vitro and in vivo activity against multiple myeloma. Haematologica in press
Khoshnan A, Ko J, Watkin EE, Paige LA, Reinhart PH and Patterson PH (2004) Activation of the IkB kinase complex and nuclear factor-kB contributes to mutant Huntingtin neurotoxicity. Journal of Neuroscience 24 7999-8008
Khoshnan A, Tindell C, Laux I, Bae D, Bennett B and Nel AE (2000) The NF-kB cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. Journal of Immunology 165 1743-1754
Khoury J, Ibla JC, Neish AS and Colgan SP (2007) Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. Journal of ClinicalInvestigation in press
Khoury M, Adiraansen J, Vervoordeldonk MJ, Gould D, Chernajovsky Y, Bigey P, Blaoquel C, Scherman D, Tak PP, Jorgensen C and Apparailly F (2007) Inflammation-inducible anti-TNF gene expression mediated by intra-articular injection of serotype 5 adeno-associated virus reduces arthritis. Journal of Gene Medicine in press
Khursigara G, Bertin J, Yano H, Moffett H, DiStefano PS and Chao MV (2001) A prosurvival function for the p75 receptor death domain mediated via the caspase recruitment domain receptor-interacting protein 2. Journal of Neuroscience 21 5854-5863
Khursigara G, Orlinick JR and Chao MV (1999) Association of the p75 neurotrophin receptor with TRAF6. Journal of Biological Chemistry 274 2597-2600
Khush RS, Cornwell WD, Uram JN and Lemaitre B (2002) A ubiquitin-proteasome pathway represses the Drosophila immune deficiency signaling cascade. Current Biology 12 1728-1737
Khush RS, Leulier F and Lemaitre B (2002) Pathogen surveillance–the flies have it. Science 296 273-275
Khush RS, Leulier F and Lemaitre B (2001) Drosophila immunity: two paths to NF-kB. Trends in Immunology 22 260-264
Khvalevsky E, Rivkin L, Rachmilewitz J, Galun E and Giladi H (2007) TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. Journal of CellularBiochemistry in press
Khwaja A (1999) Akt is more than just a Bad kinase. Nature 401 33-34
Ki SH, Choi MJ, Lee CH and Kim SG (2007) Galpha 12 specifically regulates COX-2 induction by sphingosine 1-phosphate: role for JNK-dependent ubiquitination and degradation of IkBa. Journal of Biological Chemistry 282 1938-1947
Kibbe MR, Johnnides C, Gleixner S, Kovesdi I, Lizonova A, Zuckerbraun B, Billiar TR, Tzeng E and Muluk SC (2003) Regulation of tissue factor expression in smooth muscle cells with nitric oxide. Journal of Vascular Surgery 37 650-659
Kida Y, Higashimoto Y, Inoue H, Shimizu T and Kuwano K (2008) A novel secreted protease from Pseudomonas aeruginosa activates NF-kB through protease-activated receptors. Cellular Microbiology in press
Kida Y, Inoue H, Shimizu T and Kuwano K (2006) Serratia marcescens serralysin induces inflammatory responses through protease-activated receptor-2. Infection &Immunity in press
Kida Y, Kobayashi M, Suzuki T, Takeshita A, Okamatsu Y, Hanazawa S, Yasui T and Hasegawa K (2005) Interleukin-1 stimulates cytokines, prostaglandin E(2) and matrix metalloproteinase-1 production via activation of MAPK/AP-1 and NF-kB in human gingival fibroblasts. Cytokine 29 159-168
Kidd S (1992) Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins. Cell 71 623-635
Kido J, Kido R, Suryono, Kataoka M, Fagerhol MK and Nagata T (2003) Calprotectin release from human neutrophils is induced by Porphyromonas gingivalis lipopolysaccharide via the CD-14-Toll-like receptor-nuclear factor kB pathway. Journal of Periodontal Research 38 557-563
Kido S, Inoue D, Hiura K, Javier W, Ito Y and Matsumoto T (2003) Expression of RANK is dependent upon differentiation into the macrophage/osteoclast lineage: induction by 1alpha,25-dihydroxyvitamin D(3) and TPA in a human myelomonocytic cell line, HL60. Bone 32 621-629
Kiechl S, Werner P, Knoflach M, Furtner M, Willeit J and Schett G (2006) The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease. Expert Revew ofCardiovascular Therapy 4 801-811
Kiechl S, Wiedermann CJ and Willeit J (2003) Toll-like receptor 4 and atherogenesis. Annals of Medicine 35 164-171
Kiechle FL and Zhang X (2002) Apoptosis: biochemical aspects and clinical implications. Clinica Chim Acta 326 27-45
Kiefmann R, Heckel K, Doerger M, Schenkat S, Kupatt C, Stoeckelhuber M, Wesierska-Gadek J and Goetz AE (2004) Role of PARP on iNOS pathway during endotoxin-induced acute lung injury. Intensive Care Medicine 30 1421-1431
Kielar ML, Jeyarajah DR, Penfield JG, Lu CY (2000) Docosahexaenoic acid decreases IRF-1 mRNA and thus inhibits activation of both the IRF-E and NFkB response elements of the iNOS promoter. Transplantation 69 2131-2137
Kiemer AK, Hartung T, Huber C and Vollmar AM (2003) Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kB pathway. Journal of Hepatology 38 289-297
Kiemer AK, Weber NC, Vollmar AM (2002) Induction of IkB: atrial natriuretic peptide as a regulator of the NF-B pathway. Biochemical and Biophysical Research Communications 295 1068-1076
Kieran M, Blank V, Logeat F, Vandekerckhove J, Lottspeich F, Le Bail O, Urban MB, Kourilsky P, Baeuerle PA and Israël A (1990) The DNA binding subunit of NF-kB is identical to factor KBF1 and homologous to the rel oncogene product. Cell 62 1007-1018
Kiernan RE, Bres V, Ng RW, Coudart MP, El Messaoudi S, Sardet C, Jin DY, Emiliani S and Benkirane M (2002) Post-activation turn-off of NF-kB-dependent transcription is regulated by acetylation of p65. Journal of Biological Chemistry 278 2758-2766
Kiesel J, Miller C, Abu-Amer Y and Aurora R (2007) Systems level analysis of osteoclastogenesis reveals intrinsic and extrinsic regulatory interactions.Developmental Dynamics in press
Kieser A, Kaiser C and Hammerschmidt W (1999) LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2. EMBO Journal 18 2511-2521
Kijima I, Ye J Glackin C and Chen S (2008) CCAAT/enhancer binding protein delta up-regulates aromatase promoters I.3/II in breast cancer epithelial cells. Cancer Research 68 4455-4464
Kikuchi E, Horiguchi Y, Nakashima J, Kuroda K, Oya M, Ohigashi T, Takahashi N, Shima Y, Umezawa K and Murai M (2003) Suppression of hormone-refractory prostate cancer by a novel nuclear factor kB inhibitor in nude mice. Cancer Research 63 107-110
Kikuchi H, Katsuramaki T, Kukita K, Taketani S, Meguro M, Nagayama M, Isobe M, Mizuguchi T and Hirata K (2007) New strategy for the antifibrotic therapy with oral administration of FR260330 (a selective inducible nitric oxide synthase inhibitor) in rat experimental liver cirrhosis. Wound Repair and Regeneration 15 881-888
Kikuchi H, Ozaki T, Furuya K, Hanamoto T, Nakanishi M, Yamamoto H, Yoshida K, Todo S and Nakagawara A (2006) NF-kB regulates the stability and activity of p73 by inducing its proteolytic degradation through a ubiquitin-dependent proteasome pathway. Oncogene in press
Kikuchi T, Hagiwara K, Honda Y, Gomi K, Kobayashi T, Takahashi H, Tokue Y, Watanabe A and Nukiwa T (2002) Clarithromycin suppresses lipopolysaccharide-induced interleukin-8 production by human monocytes through AP-1 and NF-kB transcription factors. Journal of Antimicrobial Chemotherapy 49 745-755
Kikuchi T, Mitani A and Noguchi T (2006) The mechanism of bone resorption in chronic inflammation of periodontal disease [Article in Japanese]. Clinical Calcium 16 241-247
Kikuchi T, Yoshikai Y, Miyoshi J, Katsuki M, Musikacharoen T, Mitani A, Tanaka S, Noguchi T and Matsuguchi T (2003) Cot/Tpl2 is essential for RANKL induction by Lipid A in osteoblasts. Journal of Dental Research 82 546-550
Kikuchi Y, Imakiire T, Hyodo T, Kushiyama T, Higashi K, Hyodo N, SUzuki S and Miura S (2005) Advanced glycation end-product induces fractalkine gene upregulation in normal rat glomeruli. Nephrology, Dialysis and Transplantation 20 2690-2696
Kikumori T, Kambe F, Nagaya T, Funahashi H and Seo H (2001) Thyrotropin modifies activation of nuclear factor kB by tumour necrosis factor alpha in rat thyroid cell line. Biochemical Journal 354 573-579
Kikuno N, Shina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Majid S, Igawa M and Dahiya R (2008) Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. International Journal of Cancer in press
Kikuno N, Shina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Place RF, Pookot D, Majid S, Igawa M and Dahiya R (2007) Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene in press
Kikuta K, Masamune A, Satoh M, Suzuki N and Shimosegawa T (2004) 4-hydroxy-2, 3-nonenal activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells. World Journal of Gastroenterology 10 2344-2351
Kil IS, Kim SY and Park JW (2008) Glutathionylation regulates IkB. Biochemical and Biophysical Research Communications in press
Kil JS, Kim MG, Choi HM, Lim JP, Boo Y, Kim EH, Kim JB, Kim HK and Leem KH (2008) Inhibitory effects of Angelicae Gigantis Radix on osteoclast formation. Phytotherapy Research 22 472-476
Kilcline C, Shinkai K, Bree A, Modica R, Von Scheven E and Frieden IJ (2005) Neonatal-onset multisystem inflammatory disorder: the emerging role of pyrin genes in autoinflammatory diseases. Archives of Dermatology 141 248-253
Killedar SY, Eckenrode SE, McIndoe RA, She JX, Nguyen CQ, Peck AB and Cha SR (2006) Early pathogenic events associated with Sjogren’s syndrome (SjS)-like disease of the nod mouse using microarray analysis. Laboratory Investigation in press
Killeen ME, Englert JA, Beer Stoltz D, Song M, Han y, Delude RL, Kellum JA and Fink MP (2005) The phase 2 enzyme inducers, ethacrynic acid, DL-sulforaphane and oltipraz, inhibit LPS-induced HMGB1 secretion by RAW 264.7 cells. Journal ofPharmacology and Experimental Therapeutics 316 1070-1079
Kilpatrick LE, Lee JY, Haines KM, Campbell DE, Sullivan KE and Korchak HM (2002) A role for PKC-delta and PI 3-kinase in TNF-a-mediated antiapoptotic signaling in the human neutrophil. American Journal of Physiology: Cell Physiology 283 C48-C57
Kilpatrick LE, Sun S and Korchak HM (2004) Selective regulation by {delta}-PKC and PI 3-kinase in the assembly of the anti-apoptotic TNFR-1 signaling complex in neutrophils. American Journal of Physiology: Cell Physiology 287 C633-C642
Kilpinen S and Hurme M (1998) Low CD3+CD28-induced interleukin-2 production correlates with decreased reactive oxygen intermediate formation in neonatal T cells. Immunology 94 167-172
Kim A, Oh JH, Park JM and Chung AS (2007) Methylselenol generated from selenomethionine by methioninase downregulates integrin expression and induces caspase-mediated apoptosis of B16F10 melanoma cells. Journal of Cellular Physiology212 386-400
Kim AJ, Kim YO, Shim JS and Hwang JK (2007) Immunostimulating activity of crude polysaccharide extract isolated from Curcuma xanthorrhiza Roxb. Bioscience,Biotechnology and Biochemistry 71 1428-1438
Kim AR, Cho JY, Lee JY, Choi JS and Chung HY (2005) Hydroquinone modulates reactivity of peroxynitrite and nitric oxide production. Journal of Pharmacy and Pharmacology 57 475-482
Kim AR, Cho JY, Zou Y, Choi JS and Chung HY (2005) Flavonoids differentially modulate nitric oxide production pathways in lipopolysaccharide-activated RAW264.7 cells. Archives of Pharmacal Research 28 297-304
Kim BE, Roh SR, Kim JW, Jeong SW and Kim IK (2003) Cytochrome C-dependent Fas-independent apoptotic pathway in HeLa cells induced by (12)-prostaglandin J(2). Experimental Molecular Medicine 35 290-300
Kim BH, Cho SM, Reddy AM, Kim YS, Min KR and Kim Y (2005) Down-regulatory effect of quercitrin gallate on nuclear factor-kB-dependent inducible nitric oxide synthase expression in lipopolysaccharide-stimulated macrophages RAW 264.7. Biochemical Pharmacology 69 1577-1583
Kim BH, Lee IJ, Lee HY, Han SB, Hong JT, Ahn B, Lee Ck and Kim Y (2007) Quercetin 3-O-beta-(2”-galloyl)-glucopyranoside inhibits endotoxin LPS-induced IL-6 expression and NF-kB activation in macrophages. Cytokine in press
Kim BH, Lee JY, Seo JH, Lee HY, Ryu SY, Ahn BW, Lee CK, Hwang BY, Han SB and Kim Y (20070 Artemisolide is a typical inhibitor of IkB kinase beta targeting cysteine-179 residue and down-regulates NF-kB-dependent TNF-a expression in LPS-activated macrophages.
Biochemical and Biophysical Research Communications in press
Kim BH, Reddy AM, Lee KH, Chung EY, Cho SM, Lee H, Min KR and Kim Y (2004) Inhibitory mechanism of chroman compound on LPS-induced nitric oxide production and nuclear factor-kB activation. Biochemical and Biophysical Research Communications 325 223-228
Kim BH, Roh E, Lee HY, Lee IJ, Ahn B, Jung SH, Lee H, Han SB and Kim Y (2008) Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-kB activation and nuclear factor-kB-regulated gene transcription through inactivating inhibitory kB kinase b. Molecular Pharmacology in press
Kim BH, Shin HM, Jung SH, Yoon YG, Min KR and Kim Y (2005) Anti-inflammatory benzene diamine compound inhibited Toll-like receptor 4-mediated inducible nitric oxide synthase expression and nuclear factor-kB activation. Biol Pharm Bull 28 908-911
Kim BJ, Kim MS, Kim KB, Kim KW, Hong YM, Kim IK, Lee HW and Jung YK (2002) Sensitizing effects of cadmium on TNF-a- and TRAIL-mediated apoptosis of NIH3T3 cells with distinct expression patterns of p53. Carcinogenesis 23 1411-1417
Kim BY, Kang DO, Oh WK, Kim JH, Choi YK, Jang JS, Suh PG, Ryu SH, Mheen TI and Ahn JS (2000) Involvement of SH2-SH2-SH3 domain of phospholipase cgamma1 in NF-kB signaling. FEBS Letters 472 45-49
Kim BY, Kim KA, Kwon O, Kim SO, Kim MS, Kim BS, Oh WK, Kim KD, Jung M and Ahn JS (2005) NF-kB inhibition radiosensitizes Ki-Ras-transformed cells to ionizing radiation. Carcinogenesis 26 1395-1403
Kim B-Y, Gaynor RB, Song K, Dritschilo A and Jung M (2002) Constitutive activation of NF-kB in Ki-ras-transformed prostate epithelial cells. Oncogene 21 4490-4497
Kim CD, Kim YK, Lee SH and Hong KW (2000) Rebamipide inhibits neutrophil adhesion to hypoxia/reoxygenation-stimulated endothelial cells via nuclear factor-kB-dependent pathway. Journal of Pharmacology and Experimental Therapeutics 294 864-869
Kim CH, Kim JH, Hsu CY and Ahn YS (1999) Zinc is required in pyrrolidine dithiocarbamate inhibition of NF-kB activation. FEBS Letters 449 28-32
Kim CH, Kim JH, Lee J and Ahn YS (2003) Zinc-induced NF-kB inhibition can be modulated by changes in the intracellular metallothionein level. Toxicology and Applied Pharmacology 190 189-196
Kim CH, Kim JH, Lee J, Hsu CY and Ahn YS (2003) Thiol antioxidant reversal of pyrrolidine dithiocarbamate-induced reciprocal regulation of AP-1 and NF-kB. Biology and Chemistry 384 143-150
Kim CH, Kim JH, Moon SJ, Chung KC, Hsu CY, Seo JT and Ahn YS (1999) Pyrithione, a zinc ionophore, inhibits NF-kB activation. Biochemical and Biophysical Research Communications 259 505-509
Kim CH, Kim JH, Moon SJ, Hsu CY, Seo JT and Ahn YS (2000) Biphasic effects of dithiocarbamates on the activity of nuclear factor-kB. European Journal of Pharmacology 392 133-136
Kim CH, Lee KH, Lee CT, Kim YW, Han SK, Shim YS and Yoo CG (2003) Aggregation of {beta}2 integrins activates human neutrophils through the IkB/NF-kB pathway. Journal of Leukocyte Biology 75 286-292
Kim CH and Moon SK (2005) Epigallocatechin-3-gallate causes the p21/WAF1-mediated G(1)-phase arrest of cell cycle and inhibits matrix metalloproteinase-9 expression in TNF-alpha-induced vascular smooth muscle cells. Archives of Biochemistry and Biophysics 435 264-272
Kim CM, Koike K, Saito I, Miyamura T and Jay G (1991) HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 353 317-320
Kim CO, Huh AJ, Kim MS, Chin BS, Han SH, Choi SH, Jeong SJ, Choi HK, Choi JY, Song YG and Kim JM (2008) Hydrogen peroxide induces the production of tumor necrosis factor-a in RAW 264.7 macrophage cells via activation of p38 and stress-activated protein kinase. Schok 30 92-97
Kim CS, Kawada T, Kim BS, Han IS, Choe SY, Kurata T and Yu R (2003) Capsaicin exhibits anti-inflammatory property by inhibiting IkB-a degradation in LPS-stimulated peritoneal macrophages. Cell Signaling 15 299-306
Kim D, Kim S, Koh H, Yoon SO, Chung AS, Cho KS and Chung J (2001) Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. FASEB Journal 15 1953-1962
Kim D, Xu M, Nie L, Peng XC, Jimi E, Voll RE, Nguyen T, Ghosh S and Sun XH (2002) Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kB activities. Immunity 16 9-21
Kim DC, Kim SH, Jeong MW, Baek NI and Kim KT (2005) Effect of rottlerin, a PKC-delta inhibitor, on TLR-4-dependent activation of murine microglia. Biochemical and Biophysical Research Communications 337 110-115
Kim DH, Kim JY, Yu BP and Chung HY (2007) The activation of NF-kB through Akt-induced FOXO1 phosphorylation during aging and its modulation by calorie restriction. Biogerontology in press
Kim DH, Kim CH, Kim MS, Kim JY, Jung KJ, Chung JH, An WG, Lee JW, Yu BP and Chung HY 2007) Suppression of age-related inflammatory NF-kB activation by cinnamaldehyde.Biogerontology in press
Kim DH, Kim HK, Park S, Kim JY, Zou Y, Cho KH, Kim YS, Kim DH, Yu BP, Choi JS and Chung HY (2006) Short-term feeding of baicalin inhibits age-associated NF-kB activation. Mechanisms of Ageing and Development in press
Kim DJ, Koh J, Lee O, Kim NJ, Lee YS, Kim YS, Park JY, Lee Ku and Kim GS (2006) Homocysteine enhances apoptosis in human bone marrow stromal cells. Bone in press
Kim DK, Cho ES, Lee BR and Um HD (2001) NF-kB mediates the adaptation of human U937 cells to hydrogen peroxide. Free Radiccal Biology and Medicine 30 563-571
Kim DM, Koo SY, Jeon K, Kim MH, Lee J, Hong CY and Jeong S (2003) Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines. Cancer Research 63 621-626
Kim DS, Ho Han J and Kwon HJ (2003) NF-kB and c-Jun-dependent regulation of macrophage inflammatory protein-2 gene expression in response to lipopolysaccharide in RAW 264.7 cells. Molecular Immunology 40 633-643
Kim DS, Jang YJ, Jeon OH and Kim DS (2007) Saxatilin inhibits TNF-a-induced proliferation by suppressing AP-1-dependent IL-8 expression in the ovarian cancer cell line MDAH 2774. Molecular Immunology 44 1409-1416
Kim DS, Park SS, Nam BH, Kim IH and Kim SY (2006) Reversal of drug resistance in breast cancer cells by transglutaminase 2 inhibition and nuclear factor-kB inactivation. Cancer Research 66 10936-10943
Kim DS, Woo ER, Chae SW, Ha KC, Lee Gh, Hong ST, Kwon DY, Kim MS, Jung YK, Kim HM, Kim HK, Kim HR and Chae HJ (2006) Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kB activation. Life Sciences in press
Kim DW, Gazourian L, Quadri SA, Romieu-Mourez R, Sherr DH and Sonenshein GE (2000) The RelA NF-kB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cells. Oncogene 19 5498-5506
Kim DW, Lenzen G, Page AL, Legrain P, Sansonetti PJ and Parsot C (2005) The Shigella flexneri effector OspG interferes with innate immune responses by targeting ubiquitin-conjugating enzymes. Proceedings of the National Academy of Sciences USA 102 14046-14051
Kim DW, Sovak MA, Zanieski G, Nonet G, Romieu-Mourez R, Lau AW, Hafer LJ, Yaswen P, Stampfer M, Rogers AE, Russo J and Sonenshein GE (2000) Activation of NF-kB/Rel occurs early during neoplastic transformation of mammary cells. Carcinogenesis 21 871-879
Kim DY, Ryu SY, Lim JE, Lee YS and ro JY (2006) Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model. European Journal of Pharmacology in press
Kim DY, Takeuchi K, Ishinaga H, Kishioka C, Suzuki S, Basbaum C and Majima Y (2004) Roxithromycin suppresses mucin gene expression in epithelial cells. Pharmacology 72 6-11
Kim E, Kang BY and Kim TS (2005) Inhibition of interleukin-12 production in mouse macrophages by hydroquinone, a reactive metabolite of benzene, via suppression of nuclear factor-kB binding activity. Immunology Letters 99 24-29
Kim E, Kim SH, Kim S and Kim TS (2006) The novel cytokine p43 induces IL-12 production in macrophages via NF-kB activation, leading to enhanced IFN-g production in CD4+ T cells. Journal of Immunology 176 256-264
Kim EH and Surh YJ (2006) 15-Deoxy-delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors. BiochemicalPharmacology in press
Kim EJ, Jin HK, Kim YK, Lee HY, Lee SY, Lee KR, Zee OP, Han JW and Lee HW (2001) Suppression by a sesquiterpene lactone from Carpesium divaricatum of inducible nitric oxide synthase by inhibiting nuclear factor-kB activation. Biochemical Pharmacology 61 903-910
Kim EJ, Kwon KJ, Park JY, Lee SH, Moon CH and Baik EJ (2002) Effects of peroxisome proliferator-activated receptor agonists on LPS- induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2. Brain Research 941 1-10
Kim EK, Kim EY, Moon PD, Um JY, Kim HM, Lee HS, Sohn Y, Park SK, Jung HS and Sohn NW (2007) Lithospermi radix extract inhibits histamine release and production of inflammatory cytokine in mast cells. Biosciennce, Biotechnology and Biochemistry in press
Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Choi KB, Ryu DG, Kim KS, Park JW and Park BH (2007) Inhibitory effect of Artemisia capillaris extract on cytokine-induced nitric oxide formation and cytotoxicity of RINm5F cells. International Journal of Molecular Medicine 19 535-540
Kim EK, Kwon KB, Han MJ, Song MY, Lee JH, Lv N, Ka SO, Yeom SR, Kwon YD, Ryu DG, Kim KS, Park JW, Park R and Park BH (2007) Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kB activation.
Experimental & Molecular Medicine 39 149-159
Kim EK, Kwon KB, Lee JH, Park BH, Park JW, Lee HK, Jhee EC and Yang JY (2007) Inhibition of cytokine-mediated nitric oxide synthase expression in rat insulinoma cells by scoparone. Biological and Pharmaceutical Bulletin 30 242-246
Kim EK, Kwon KB, Shin BC, Seo EA, Lee YR, Kim JS, Park JW, Park BH and Ryu DG (2005) Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kB and caspase-3. Life Sciences 77 824-836
Kim EK, Kwon KB, Song MY, Han MJ, Lee JH, Lee YR, Lee JH, Ryu DG, Park BH and Park JW (2007) Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation. Pancrease 35 e1-e9
Kim EY and Teh HS (2004) Critical role of TNF receptor type-2 (p75) as a costimulator for IL-2 induction and T cell survival: a functional link to CD28. Journal of Immunology 173 4500-4509
Kim F, Pham M, Luttrell I, Bannerman DD, Tupper J, Thaler J, Hawn TR, Raines EW and Schwartz MW (2007) Toll like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circulation Research in press
Kim F, Tysseling KA, Rice J, Pham M, Haji L, Gallis BM, Baas AS, Paramsothy P, Giachelli CM, Corson MA and Raines EW (2005) Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta. Arteriosclerosis, Thrombosis and Vascular Biology 25 989-994
Kim GM, Xu J, Song SK, Yan P, Ku G, Xu XM and Hsu CY (2001) Tumor necrosis factor receptor deletion reduces nuclear factor-kB activation, cellular inhibitor of apoptosis protein 2 expression, and functional recovery after traumatic spinal cord injury. Journal of Neuroscience 21 6617-6625
Kim GY, Han MG, Song YS, Shin BC, Shin YI, Lee HJ, Moon DO, Lee CM, Kwak JY, Bae YS, Lee JD and Park YM (2004) Proteoglycan isolated from Phellinus linteus induces Toll-like receptors 2- and 4-mediated maturation of murine dendritic cells via activation of ERK, p38, and NF-kB. Biol Pharm Bull 27 1656-1662
Kim GY, Kim JH, Ahn SC, Lee HJ, Moon DO, Lee CM and Park YM (2004) Lycopene suppresses the lipopolysaccharide-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and nuclear factor-kB. Immunology 113 203-211
Kim GY, Kim KH, Lee SH, Yoon MS, Lee HJ, Moon DO, Lee CM, Ahn SC, Park YC and Park YM (2005) Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kB as potential targets. Journal of Immunology 174 8116-8124
Kim H (2005) Oxidative stress in Helicobacter pylori-induced gastric cell injury. Inflammopharmacology 13 63-74
Kim H (2006) DNA repair Ku proteins in gastric cancer cells and pancreatic acinar cells. Amino Acids in press
Kim H, Chung H,Kim HJ, Lee JY, Oh MY,Kim Y and Kong G (2007) Id-1 regulates Bcl-2 and Bax expression through p53 and NF-kB in MCF-7 breast cancer cells. Breast Cancer Research and Treatment in press
Kim H, Hwang JS, Woo CH, Kim EY, Kim TH, Choo KJ, Kim JH, Seo JM and Lee SS (2008) TNF-a-induced up-regulation of intercellular adhesion molecule-1 is regulated by a Rac-ROS-dependent cascade in human airway epithelial cells. Experimental and Molecular Medicine 40 167-175
Kim H, Kim BY, Soh JW, Cho EJ, Liu JO and Youn HD (2006) A novel function of Nur77: Physical and functional association with protein kinase C. Biochemical andBiophysical Research Communications in press
Kim H, Kim YN, Kim H and Kim CW (2005) Oxidative stress attenuates Fas-mediated apoptosis in Jurkat T cell line through Bfl-1 induction. Oncogene 24 1252-1261
Kim H, Kim YS, Kim SY and Suk K (2001) The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. Neuroscience Letters 309 67-71
Kim H, Lee YH, Won J and Yun Y (2001) Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation through AP-1, NF-kB, and SRE enhancers. Biochemical and Biophysical Research Communications 286 886-894
Kim H, Rhee SH, Pothoulakis C and Lamont JT (2007) Inflammation and apoptosis in Clostridium difficile enteritis is mediated by PGE(2) up-regulation of Fas ligand.Gastroenterology 133 875-886
Kim H, Seo JY and Kim KH (1999) Effects of mannitol and dimethylthiourea on helicobacter pylori-induced IL-8 production in gastric epithelial cells. Pharmacology 59 201-211
Kim H, Seo JY and Kim KH (2000) Inhibition of lipid peroxidation, NF-kB activation and IL-8 production by rebamipide in Helicobacter pylori-stimulated gastric epithelial cells. Dig Dis Sci 45 621-628
Kim H, Yang E, Lee J, Kim SH, Shin JS, Park JY, Choi SJ, Kim SJ and Choi IH (2008) Double-stranded RNA mediates interferon regulatory factor 3 activation and interleukin-6 production by engaging Toll-like receptor 3 in human brain astrocytes. Immunology in press
Kim H, Yi JW, Sung YH, Kim CJ, Kim CS and Kang JM (2008) Delayed preconditioning effect of isoflurane on spinal cord ischemia in rats. Neuroscience Letters in press
Kim HA, Kim SH, Ko HM, Choi JH, Kim KJ, Oh SH, Cho KO, CHoi IW and Im SY (2008) Nitric oxide plays a key role in the platelet-activating factor-induced enhancement of resistance against systemic candidiasis. Immunology in press
Kim HA, Lee KB and Bae SC (2005) The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death. Arthritis Research and Therapy 7 R526-R535
Kim HA, Cho ML, Choi HY, Yoon CS, Jhun JY, Oh HJ and Kim HY (2006) The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.Arthritis and Rheumatism 54 2152-2163
Kim HA and Song YW (2002) TNF-a-mediated apoptosis in chondrocytes sensitized by MG132 or actinomycin D. Biochemical and Biophysical Research Communications 295 937-944
Kim HB, Lee KH, Chung EY, Chang YS, Lee H, Lee CK, Min KR and Kim Y (2006)Inhibitory effect of chroman carboxamide on interleukin-6 expression in response to lipopolysaccharide by preventing nuclear factor-kB activation in macrophages.European Jounral of Pharmacology 543 158-165
Kim HE, Choi SE, Lee SJ, Lee JH, Lee YJ, Kang SS, Chun J and Kang Y (2008) TNFa-induced GSIS inhibition in INS-1 cells is ascribed to a reduction of the glucose-stimulated Ca2+ influx. Journal of Endocrinology in press
Kim HG, Kimm NR, Gim MG, Lee JM, Lee SY, Ko MY, Kim JY, Han SH and Chung DK (2008) Lipoteichoic acid isolated from Lactobacillus plantarum inhibits lipopolysaccharide-induced TNF-a production in THP-1 cells and endotoxin shock in mice. Journal of Immunology 180 2553-2561
Kim HG, Lee SY, Kim NR, Ko MY, Lee JM, Yi TH, Chung SK and Chung DK (2008) Inhibitory effects of Lactobacillus plantarum lipoteichoic acid (LTA) on Staphylococcus aureus LTA-induced tumor necrosis factor-a production. Journal of Miicrobiology and Technology 18 1191-1196
Kim HG, Shrestha B, Lim SY, Yoon DH, Chang WC, Shin DJ, Han SK, Park SM, Park JH, Park HI, Sung JM, Jang Y, Chung N, Hwang KC and Kim TW (2006) Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kB through Akt and p38 inhibition in RAW 264.7 macrophage cells. European Journal of Pharmacology 545 192-199
Kim HG, Yoon DH, Kim CH, Shrestha B, Chang WC, Lim SY, Lee WH, Han SG, Lee JO, Lim MH, Kim GY, Choi S, Song WO, Sung JM, Hwang KC and Kim TW (2007) Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells. Journal of Medicinal Food 10 80-89
Kim HG, Yoon DH, Lee WH, Han SK, Shretha B, Kim CH, Lim MH, Chang W, Lim S, CHoi S, Song WO, Sung JM, Hwang KC and Kim TW (2007) Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage. Journal of Ethnopharmacology in press
Kim HH (1999) Characterization of the NF-kB activation induced by TR8, an osteoclastogenic tumor necrosis factor receptor family member. Archives of Pharmacal Research 22 454-458
Kim HH, Kim JH, Kwak HB, Huang H, Han SH, Ha H, Lee SW, Woo ER and Lee ZH (2004) Inhibition of osteoclast differentiation and bone resorption by tanshinone IIA isolated from Salvia miltiorrhiza Bunge. Biochemical Pharmacology 67 1647-1656
Kim HH, Lee Y, Eun HC and Chung JH (2008) Eicosapentaenoic acid inhibits TNF-a-induced matrix metalloproteinase-9 expression in human keratinocytes, HaCaT cells. Biochemical and Biophysical Research Communications in press
Kim HJ, Byun SJ and Kim TY (2004) Differential regulation of IGF-II-induced IL-8 by extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinases in human keratinocytes. Biochemical and Biophysical Research Communications 317 276-284
Kim HJ, Chang EJ, Kim HM, Lee SB, Kim HD, Su Kim G and Kim HH (2006) Antioxidant a-lipoic acid inhibits osteoclast differentiation by reducing nuclear factor-kB DNA binding and prevents in vivo bone resorption induced by receptor activator of nuclear factor-kB ligand and tumor necrosis factor-a. Free Radical Biology and Medicine 40 1483-1493
Kim HJ, Hawke N and Baldwin AS (2006) NF-kB and IKK as therapeutic targets in cancer. Cell Death and Differentiation in press
Kim HJ, Jung KJ, Yu BP, Cho CG, Choi JS and Chung HY (2002) Modulation of redox-sensitive transcription factors by calorie restriction during aging. Mechanisms of Ageing and Development 123 1589-1595
Kim HJ, Kim HY, Kim BK, Kim S and Chung DH (2006) Engagement of glucocorticoid-induced TNF receptor costimuates NKT cell activation in vitro and in vivo. Journal of Immunology 176 3507-3515
Kim HJ, Kim KW, Yu BP and Chung HY (2000) The effect of age on cyclooxygenase-2 gene expression: NF-kB activation and IkBa degradation. Free Radical Biology and Medicine 28 683-692
Kim HJ, Lee HS, Chong YH and Kang JL (2006) p38 mitogen-activated protein kinase up-regulates LPS-induced NF-kB activation in the development of lung injury and RAW 264.7 macrophages. Toxicology 225 36-47
Kim HJ, Lee Y, Chang EJ, Kim HM, Hong SP, Lee ZH, Ryu J and Kim HH (2007) Suppression of osteoclastogenesis by N,N-dimethyl-D-erythro-sphingosine: a sphingosine kinase inhibition-independent action. Molecular Pharmacology in press
Kim HJ, Litzenburger BC, Cui X, Delgado DA, Grabiner BC, Lin X, Lewis MT, Gottardis MM, Wong TW, Attar RM, Carboni J and Lee AV (2007) Constitutively active IGF-IR causes transformation and xenograft growth of immortalized mammary epithelial cells, and is accompanied by an epithelial to mesenchymal transition mediated by NF-kB and Snail. Molecular and Cellular Biology in press
Kim HJ, Park JK and Kim YG (1999) Suppression of NF-kB activation in normal T cells by supernatant fluid from human renal cell carcinomas. Journal of Korean Medical Sciences 14 299-303
Kim HJ, Park KG, Yoo EK, Kim YH, Kim YN, Kim HS, Kim HT, Park JY, Lee KU, Jang WG,Kim JG, Kim BW and Lee IK (2007) Effects of PGC-1alpha on TNF-alpha-induced MCP-1 and VCAM-1 expression and NF-kB activation in human aortic smooth muscle and endothelial cells. Antioxidant and Redox Signaling in press
Kim HJ, So HS, Lee JH, Park C, Lee JB, Youn MJ, Kim SJ, Yang SH, Lee KM, Kwon KB, Park BH and Park R (2008) Role of proinflammatory cytokines in cisplatin-induced vestibular hair cell damage. Head and Neck in press
Kim HK, Kim JE, Chung J, Kim YT, Kang Sh, Han SH and Cho HI (2007) Lipopolysaccharide down-regulates the thrombomodulin expression of peripheral blood monocytes: effect of serum on thrombomodulin expression in the THP-1 monocytic cell line. Blood Coagulation & Fibrinolysis 18 157-164
Kim HK, Park HR, Lee JS, Chung TS, Chung HY and CHung J (2007) Down-regulation of iNOS and TNF-a expression by kaempferol via NF-kB inactivation in aged rat gingival tissues. Biogerontology in press
Kim HS, Lee YK, Kim JW, Baik SK, Kwon SO and Jang HI (2006) Modulation of colon cancer cell invasiveness induced by deoxycholic aci [Article in Korean]. Korean Journal of Gastroenterology 48 9-18
Kim HS, Loughran PA, Kim PK, Billiar TR and Zuckerbraun BS (2006) Carbon monoxide protects hepatocytes from TNF-a/actinomycin D by inhibition of the caspase-8-mediated apoptotic pathway.
Biochemical and Biophysical Research Communications 344 1172-1178
Kim HS, Loughran P, Rao J, Billiar TR and Zuckerbraun BS (2008) Carbon monoxide activates NF-kB via ROS generation and Akt Pathways to protect against cell death Of hepatocytes. American Journal of Physiology: Gastrointestinal and Liver Physiology in press
Kim HY and Kim HS (2006) Upregulation of MIP-2 (CXCL2) expression by 15-deoxy-Delta(12,14)-prostaglandin J(2) in mouse peritoneal macrophages. Immunology and Cell Biology in press
Kim HY, Rho YH, Choi SJ, Lee YH, Cheon HJ, Um JW, Sohn J, Song GG and Ji JD (2005) 15-Deoxy-delta(12,14)-PGJ(2)inhibits IL-6-induced Stat3 phosphorylation in lymphocytes. Experimental and Molecular Medicine 37 179-185
Kim HJ, Yu BP and Chung HY (2002) Molecular exploration of age-related NF-kB/IKK downregulation by calorie restriction in rat kidney. Free Radical Biology and Medicine 32 991-1005
Kim HJ, Tsoy I, Heo JM, Kang YJ, Park MK, Lee YS, Lee JH, Seo HG, Yun-Choi HS and Chang KC (2006) Regulation of lipopolysaccharide-induced inducible nitric oxide synthase expression through nuclear factor-kB pathway and IFN-{beta}/Tyk2/JAK2-STAT-1 signaling cascades by 2-naphtylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid. Journal of Pharmacology andExperimental Therapeutics in press
Kim HJ, Tsoy I, Park JM, Chung JI, Shin SC and Chang KC (2006) Anthocyanins from soybean seed coat inhibit the expression of TNF-a-induced genes associated with ischemia/reperfusion in endothelial cell by NF-kB-dependent pathway and reduce rat myocardial damages incurred by ischemia and reperfusion in vivo.
FEBS Letters 580 1391-1397
Kim HK, Park HR, Sul KH, Chung HY and Chnung J (2006) Induction of RANTES and CCR5 through NF-kB activation via MAPK pathway in aged rat gingival tissues.Biotechnology Letters 28 17-23
Kim HM, Bae SJ, Kim DW, Kim BK, Lee SB, Lee US, Kim CH and Moon SK (2007) Inhibitory role of magnolol on proliferative capacity and matrix metalloproteinase-9 expression in TNF-alpha-induced vascular smooth muscle cells. International Immunopharmacology 7 1083-1091
Kim HR, Cho ML, Kim KW, Juhn JY, Hwang SY, Yoon CH, Park Sh, Lee SH and Kim HY (2006) Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-, NF-kB- and p38 MAPK-dependent signalling pathways. Rheumatology (Oxford) 46 57-64
Kim HR, Kim S, Kim EJ, Park JH, Yang SH, Jeong ET, Park C, Youn MJ, So HS and Park R (2007) Suppression of Nrf2-driven heme oxygenase-1 enhances the chemosensitivity of lung cancer A549 cells toward cisplatin. Lung Cancer in press
Kim HS, Chang I, Kim JY, Choi KH and Lee MS (2005) Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis. Cancer Research 65 6111-6119
Kim HS, Kim HJ, Park KG, Kim YN, Kwon TK, Park JY, Lee KU, Kim JG and Lee IK (2007) alpha-Lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kB transcriptional activity. Experimental & Molecular Medicine 39 106-113
Kim HS, Kim S and Lee MS (2005) IFN-g sensitizes MIN6N8 insulinoma cells to TNF-a-induced apoptosis by inhibiting NF-kB-mediated XIAP upregulation. Biochemical and Biophysical Research Communications 336 847-853
Kim HS, Oh JM, KJIn DH, Yang KH and Moon EY (2008) Paclitaxel induces vascular endothelial growth factor expression through reactive oxygen species production. Pharmacology 81 317-324
Kim HY, Kim JR and Kim HS (2008) Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages. Journal of Microbiology and Biotechnology 18 1170-1178
Kim HS, Wang SY, Woo MS, Park JS, Kim WK and Han IO (2004) Sodium butyrate suppresses interferon-gamma-, but not lipopolysaccharide-mediated induction of nitric oxide and tumor necrosis factor-alpha in microglia. Journal of Neuroimmunology 151 85-93
Kim HY, Kang YJ, Song IH, Choi HC and Kim HS (2008) Upregulation of interleukin-8/CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension Research 31 515-523
Kim HY, Kim HK, Kim JR and Kim HS (2005) Upregulation of LPS-induced chemokine KC expression by 15-deoxy-Delta-prostaglandin J in mouse peritoneal macrophages.Immunol Cell Biol 83 286-293
Kim HY and Rikihisa Y (2002) Roles of p38 Mitogen-Activated Protein Kinase, NF-kB, and Protein Kinase C in Proinflammatory Cytokine mRNA Expression by Human Peripheral Blood Leukocytes, Monocytes, and Neutrophils in Response to Anaplasma phagocytophila. Infection & Immunity 70 4132-4141
Kim I, Kim JH, Ryu YS, Liu M and Koh GY (2000) Tumor necrosis factor-alpha upregulates angiopoietin-2 in human umbilical vein endothelial cells. Biochemical and Biophysical Research Communications 269 361-365
Kim I, Moon SO, Kim SH, Kim HJ, Koh YS and Koh GY (2001) VEGF stimulates expression of ICAM-1, VCAM-1 and E-selectin through nuclear factor-kB activation in endothelial cells. Journal of Biological Chemistry 276 7614-7620
Kim I, Oh JL, Ryu YS, So JN, Sessa WC, Walsh K and Koh GY (2002) Angiopoietin-1 negatively regulates expression and activity of tissue factor in endothelial cells. FASEB Journal 16 126-128
Kim IS, Kim JH, Kim JS, Yun CY, Kim DH and Lee JS (2007) The inhibitory effect of Houttuynia cordata extract on stem cell factor-induced HMC-1 cell migration. Journal of Ethnopharmacology in press
Kim IK, Li CC, Young HA, Lee JH, Kim HS, Pardhasaradhi K, Garcia GE, Chiang PK (1997) Apoptosis of L1210 leukemia cells induced by 3-deazaadenosine analogs: differential expression of c-myc, NF-kB and molecular events. Journal of Biomedical Sciences 4 83-90
Kim IT, Park HJ, Nam JH, Park YM, Won JH, Choi J, Choe BK and Lee KT (2005) In-vitro and in-vivo anti-inflammatory and antinociceptive effects of the methanol extract of the roots of Morinda officinalis. Journal of Pharmacy and Pharmacology 57 607-616
Kim IT, Park YM, Won JH, Jung HJ, Park HJ, Choi JW and Lee KT (2005) Methanol extract of Xanthium strumarium L. possesses anti-inflammatory and anti-nociceptive activities. Biol Pharm Bull 28 94-100
Kim J (2005) Review of the innate immune response in Acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. Dermatology211 193-198
Kim J, Bates DG, Postlethwaite I, Heslop-Harrison P and Cho KH (2007) Least-squares methods for identifying biochemical regulatory networks from noisy measurements. BMC Bioinformatics 8 8
Kim J, Hwang JS, Cho YK, Han Y, Jeon YJ and Yang KH (2001) Protective effects of (-)-epigallocatechin-3-gallate on UVA- and UVB-induced skin damage. Skin Pharmacology and Applied Skin Physiology 14 11-19
Kim J, Kim C and Kim-Ha J (2006) Ovarian tumors in Rbp9 mutants of Drosophila induce an immune response. Molecules and Cells 22 228-232
Kim J, Kim H, Jeun S, Rha S, Kim Y, Ko Y, Won J, Lee K, Rha H and Wang Y (2002) Inhibition of NF-kB activation by merlin. Biochemical and Biophysical Research Communications 296 1295-1302
Kim J, Kim HR, Bae J, Kim DH, Kim HJ, Lee HK and Choi SH (2004) Cross-linking of MHC class II molecules with anti-MHC class II antibody or epitope peptide prevents resting B lymphocyte differentiation by inhibiting NF-kB-dependent gene expression. Molecules and Cells 12 67-76
Kim J and Kim-Ha J (2006) Ovarian tumors in rbp9 mutants of Drosophila induce and immune response. Molecules and Cells 22 228-232
Kim J, Lee H, Oh BG, Cho C, Kim Y, Shin M, Hong M, Jung SK and Bae H (2007) Inhibition effects of Moutan Cortex Radicis on secretion of eotaxin in A549 human epithelial cells and eosinophil migration.
Journal of Ethnopharmacology in press
Kim J, Nam KH, Kim SO, Choi JH, Kim HC, Yang SD, Kang JH, Ryu YH, Oh GT and Yoo SE (2004) KR-31378 ameliorates atherosclerosis by blocking monocyte recruitment in hypercholestrolemic mice. FASEB Journal 18 714-716
Kim J, Ochoa MT, Krutzik SR, Takeuchi O, Uematsu S, Legaspi AJ, Brightbill HD, Holland D, Cunliffe WJ, Akira S, Sieling PA, Godowski PJ and Modlin RL (2002)Activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. Journal of Immunology 169 1535-1541
Kim J, Sanders SP, Siekierski ES, Casolaro V and Proud D (2000) Role of NF-kB in cytokine production induced from human airway epithelial cells by rhinovirus infection. Journal of Immunology 165 3384-3392
Kim J, Shao Y, Kim SY, Kim S, Song HK, Jeon JH, Woo Suh H, Chung JW, Yoon SR, Kim YS and Choi I (2007) Hypoxia-induced IL-18 increases hypoxia-inducible factor-1alpha expression through a Rac1-dependent NF-kB pathway. Molecular Biology of the Cell in press
Kim J, Son JW, Lee JA, Oh YS and Shinn SH (2004) Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes. Korean Journal of Medical Science 19 95-100
Kim JA, Kim DK, Jin Tae, Kang OH, Choi YA, Choi SC, Kim TH, Nah YH, Choi SJ, Kim YH, Bae KH and Lee YM (2004) Acanthoic acid inhibits IL-8 production via MAPKs and NF-kB in a TNF-alpha-stimulated human intestinal epithelial cell line. Clinica Chimica Acta 342 193-202
Kim JA, Kim DK, Kang OH, Choi YA, Park HJ, Choi SC, Kim TH, Yun KJ, Nah YH and Lee YM (2005) Inhibitory effect of luteolin on TNF-alpha-induced IL-8 production in human colon epithelial cells. International Immunopharmacology 5 209-217
Kim JA, Tay D and Blanco EC (2008) NF-kB inhibitory activity of compounds isolated from Cantharellus cibarius. Phytotherapy Research in press
Kim JB, Han AR, Park EY, Kim JY, Cho W, Lee J, Seo EK and Lee KT (2007) Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by Poncirin through the NF-kB inactivation in RAW 264.7 macrophage cells. Biological and Pharmacological Bulletin 30 2345-2351
Kim JB, Yu YM, Kim SW and Lee JK (2005) Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain. Brain Research 1060 188-192
Kim JC, Lee SY, Kim SY, Kim JK, Kim HJ, Lee HM, Choi MS, Min JS, Kim MJ, Choi HS and Ahn JK (2008) Regulation of the maturation of osteoblasts and osteoclastogenesis by glutamate. FEBS Letters in press
Kim JD, Choi BK, Bae JS, Lee UH, Han IS, Lee HW, Youn BS, Vinay DS and Kwon BS (2003) Cloning and characterization of GITR ligand. Genes & Immunity 4 564-569
Kim JG, Kim JH, Lee DO, Kim H, Kim JY, Suh CS, Kim SH and Choi YM (2007) Changes in the serum levels of osteoprotegerin and soluble receptor activator for nuclear factor kappaB ligand after estrogen-progestogen therapy and their relationships with changes in bone mass in postmenopausal women. Menopause in press
Kim JG, Lee SJ and Kagnoff MF (2004) Nod1 is an essential signal transducer in intestinal epithelial cells infected with bacteria that avoid recognition by toll-like receptors. Infection & Immunity 72 1487-1495
Kim JH, Jung JH, Jeon ST, Kim H, Ock J, Suk K, Kim SI, Song KS and Lee WH (2006) Decursin inhibits induction of inflammatory mediators by blocking NF-kB activation in macrophages. Molecular Pharmacology 69 1783-1790
Kim JH, Kim B, Cai L, Choi HJ, Ohgi KA, Tran C, Chen C, Chung CH, Huber O, Rose DW, Sawyers CL, Rosenfeld MG and Baek SH (2005) Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature 434 921-926
Kim JH, Kim DH, Baek SH, Lee HJ, Kim MR, Kwon HJ and Lee CH (2006) Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-kB and p38 MAP kinase activity in LPS-stimulated RAW 264.7 cells. Biochemical Pharmacology 71 1198-1205
Kim JH, Kim HN, Lee KT, Lee JK, Choi SH, Paik SW, Rhee JC and Lowe AW (2008) Gene expression profiles in gallbaladder cancer: the close genetic cimilarity seen for earlya nd advanced gallbladder cancers may explain the poor prognosis. Tumour Biology 29 41-49
Kim JH, Kim KY, Jeon JH, Lee SH, Hwang JE, Lee JH, Kim KK, Lim JS, Kim KI, Moon EY, Lee HG, Ryu JH and Yang Y (2008) Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells. Cancer Letters 261 253-262
Kim JH, Lee KW, Lee MW, Lee HJ, Kim SH and Surh YJ (2006) Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kB as a potential molecular target. FEBS Letters 580 385-392
Kim JH, Na HJ, Kim CK, Kim JY, Ha KS, Lee H, Chung HT, Kwon HJ, Kwon YG and Kim YM (2008) The non-provitamin A carotenoid, lutein, inhibits NF-kB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: Role of H(2)O(2) in NF-kB activation. Free Radical Biology and Medicine in press
Kim JH, Na HK, Pak YK, Lee YS, Lee SJ, Moon A and Surh YJ (2007) Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-kB activation and COX-2 expression in human breast epithelial cells. Chemicao-Biological Interactions in press
Kim JH, Soo Ha I, Hwang CI, Lee YJ, Kim J, Yang SH, Kim YS, Cao YA, Choi S and Park WY (2004) Gene expression profiling of anti-GBM glomerulonephritis model: The role of NF-kB in immune complex kidney disease. Kidney International 66 1826-1837
Kim JH, Xu C, Keum YS, Reddy B, Conney A and Kong AN (2006) Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin. Carcinogeneis 27 475-482
Kim JI, Kin JK, Choi EK, Spinner D, Rubenstein R, Carp RI and Kim YS (2007) Increased expression and localization of cyclooxygenase-2 in astrocytes of scrapie-infected mice. Journal of Neuroimmunology in press
Kim JI, Ju WK, Choi JH, Choi E, Carp RI, Wisniewski HM and Kim YS (1999) Expression of cytokine genes and increased nuclear factor-kB activity in the brains of scrapie-infected mice. Brain Research Molecular Brain Research 73 17-27
Kim JK, Kim KD, Lee E, Lim JS, Cho HJ, Yoon HK, Cho MY, Baek KE, Park YP, Paik SG, Choe YK and Lee HG (2004) Up-regulation of Bfl-1/A1 via NF-kB activation in cisplatin-resistant human bladder cancer cell line. Cancer Letters 212 61-70
Kim JK, Kim Y, Na KM, Surh YJ and Kim TY (2007) [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. Free Radical Research 41 603-614
Kim JK, Oh SM, Kwon HS, Oh YS, Lim SS and Shin HK (2006) Anti-inflammatory effect of roasted licorice extracts on lipopolysaccharide-induced inflammatory responses in murine macrophages. Biochemical and Biophysical Research Communications 345 1215-1223
Kim JM, Cho SJ, Oh YK, Jung HY and Kim YJ (2002) Nuclear factor-kB activation pathway in intestinal epithelial cells is a major regulator of chemokine gene expression and neutrophil migration induced by Bacteroides fragilis enterotoxin. Clinical and Experimental Immunology 130 59-66
Kim JM, Jeong D, Kang HK, Jung SY, Kang SS and Min BM (2007) Osteoclast precursors display dynamic metabolic shifts toward accelerated glucose metabolism at an early stage of RANKL-stimulated osteoclast differentiation. Cell Physiology and Biochemistry 20 935-946
Kim JM, Kim JS, Jung HC, Oh YK, Chung HY, Lee CH and Song IS (2003) Helicobacter pylori infection activates the NF-kB signaling pathway to induce iNOS and protect human gastric epithelial cells from apoptosis. American Journal of Physiology: Gastrointestintal Liver Physiology 285 G1171-G1180
Kim JM, Kim JS, Jung HC, Oh YK, Kim N and Song IS (2003) Inhibition of Helicobacter pylori-induced Nuclear Factor-kB activation and interleukin-8 gene expression by ecabet sodium in gastric epithelial cells. Heliobacter 8 542-553
Kim JM, Kim JS, Kim YJ, Oh YK, Kim IY, Chee YJ, Han JS and Jung HC (20080 Conjugated linoleic acids produced by Lactobacillus dissociates IKK-gamma and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells. Laboratory Investigation in press
Kim JM, Lee SU, Kim YS, Min YK and Kim SH (2008) Baicalein stimulates osteoblast differentiation via coordinating activation of MAP kinases and transcription factors. Journal of Cellular Biochemistry in press
Kim JS, Kim JS, Lee JY, Kim YJ, Youn HJ, Kim IY, Chee YJ, Oh YK, Kim N, Jung HC and Song IS (2007) Vacuolating cytotoxin in Helicobacter pylori water-soluble proteins upregulates chemokine expression in human eosinophils via Ca2+ influx, mitochondrial reactive oxygen intermediates, and NF-kB activation. Infection and Immunity in press
Kim JM, Kim NI, Oh YK, Kim YJ, Youn J and Ahn MJ (2005) CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kB-independent pathways. International Immunology 17 1525-1531
Kim JM, Lee JY, Yoon YM, Oh YK, Kang JS, Kim YJ and Kim KH (2006) Bacteroides fragilis enterotoxin induces cyclooxygenase-2 and fluid secretion in intestinal epithelial cells through NF-kB activation. European Journal of Immunology 36 2446-2456
Kim JM, Lee JY, Yoon YM, Oh YK, Youn J and Kim YJ (2006) NF-kB activation pathway is essential for the chemokine expression in intestinal epithelial cells stimulated with Clostridium difficile toxin A. Scandinvain Journal of Immunology 63 453-460
Kim JM, Min SK, Kim H, Kang HK, Jung SY, Lee SH, Choi Y, Roh S, Jeong D and Min BM (2007) Vacuolar-type H+-ATPase-mediated acidosis promotes in vitro osteoclastogenesis via modulation of cell migration. International Journal of Molecular Medicine 19 393-400
Kim JM, Oh YK, Kim YJ, Oh HB and Cho YJ (2001) Polarized secretion of CXC chemokines by human intestinal epithelial cells in response to Bacteroides fragilis enterotoxin: NF-kB plays a major role in the regulation of IL-8 expression. Clinical and Experimental Immunology 123 421-427
Kim JM, Oh YK, Kim YJ, Youn J and Ahn MJ (2004) Escherichia coli up-regulates proinflammatory cytokine expression in granulocyte/macrophage lineages of CD34 stem cells via p50 homodimeric NF-kB. Clinical and Experimental Immunology 137 341-350
Kim JM, Oh YK, Lee JH, Im DY, Kim YJ, Youn J, Lee CH, Son H, Lee YS, Park JY and Choi IH (2005) Induction of proinflammatory mediators requires activation of the TRAF, NIK, IKK and NF-kB signal transduction pathway in astrocytes infected with Escherichia coli. Cinical and Experimental Immunology 140 450-460
Kim JO, Kim HW, Baek KM and Kang CY (2003) NF-kappaB and AP-1 regulate activation-dependent CD137 (4-1BB) expression in T cells. FEBS Letters 541 163-170
Kim JS, Lee JM, Chwae YJ, Kim YH, Lee JH, Kim K, Lee TH, Kim SJ and Park JH (2004) Cisplatin-induced apoptosis in Hep3B cells: mitochondria-dependent and -independent pathways. Biochemical Pharmacology 67 1459-1468
Kim JS and Jobin C (2004) Role of NF-kB in inflammatory disorders: just when you thought you knew everything! Journal of Pediatric Gastroenterology and Nutrition 38 109-110
Kim JS and Jobin C (2005) The flavonoid luteolin prevents lipopolysaccharide-induced NF-kB signalling and gene expression by blocking IkB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells. Immunology 115 375-387
Kim JS, Kim JM, Jung HC and Song IS (2001) Expression of cyclooxygenase-2 in human neutrophils activated by Helicobacter pylori water-soluble proteins: possible involvement of NF-kB and MAP kinase signaling pathway. Dig Dis Sci 46 2277-2284
Kim JS, Lee HJ, Lee MH, Kim J, Jin C and Ryu JH (2006) Luteolin inhibits LPS-stimulated inducible nitric oxide synthase expression in BV-2 microglial cells.Planta Medica 72 65-68
Kim JS, Narula AS and Jobin C (2005) Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kB signalling in intestinal epithelial cells. Clinical and Experimental Immunology 141 288-297
Kim JW, Choi EJ and Joe CO (2000) Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP. Oncogene 19 4491-4499
Kim JW, Joe CO and Choi EJ (2001) Role of receptor-interacting protein in tumor necrosis factor-alpha-dependent MEKK1 activation. Journal of Biological Chemistry 276 27064-27070
Kim JY, Ahn MH, Jun HS, Jung JW, Ryu JS and Min DY (2006) Toxoplasma gondii inhibits apoptosis in infected cells by caspase inactivation and NF-kB activation. Yonsei Medical Journal 47 862-869
Kim JY, Byeon SE, Lee YG, Lee JY, Park J, Hong EK and Cho JY (2008) Immunostimulatory activities of polysaccharides from liquid culture of pine-mushroom Tricholoma matsutake. Journal of Microbiology and Biotechnology 18 95-103
Kim JY, Choi CY, Lee KJ, Shin DW, Jung KS, Chung YC, Lee SS, Shin JG and Jeong HG (2004) Induction of inducible nitric oxide synthase and proinflammatory cytokines expression by o,p’-DDT in macrophages. Toxicology Letters 147 261-269
Kim JY, Jung KJ, Choi JS and Chung HY (2006) Modulation of the age-related nuclear factor-kB (NF-kB) pathway by hesperetin. Aging Cell in press
Kim JY, Kim DH, Kim HG, Song GY, CHung YC, Roh SH and Jeong HG (2005) Inhibition of tumor necrosis factor-a-induced expression of adhesion molecules in human endothelial cells by the saponins derived from roots of Platycodon grandiflorum. Toxicology and Applied Pharmacology 210 150-156
Kim JY, Kim TH and Kim SS (2008) Anti-inflammatory effect of a human prothrombin fragment-2-derived peptide, NSA9, in EOC2 microglia. Biochemical and Biophysical Research Communications in press
Kim JY, Jung KS and Jeong HG (2004) Suppressive effects of the kahweol and cafestol on cyclooxygenase-2 expression in macrophages. FEBS Letters 569 321-326
Kim JY and Kim C (2005) Inhibition of LPS-induced NO production by taurine chloramine in macrophages is mediated through Ras-ERK-NF-kB. Biochemical Pharmacology 70 1352-1360
Kim JY, Kim H, Lee SG, Choi BH, Kim YH, Huh PW, Lee KH, Han H and Rha HK (2003) Amyloid beta peptide (Abeta42) activates PLC-delta1 promoter through the NF-kB binding site. Biochemical and Biophysical Research Communications 310 904-909
Kim JY and Jeong HG (2003) Down-regulation of inducible nitric oxide synthase and tumor necrosis factor-a expression by bisphenol A via nuclear factor-kB inactivation in macrophages. Cancer Letters 196 69-76
Kim JY, Jung KS, Lee KJ, Na HK, Chun HK, Kho YH and Jeong HG (2004) The coffee diterpene kahweol suppress the inducible nitric oxide synthase expression in macrophages. Cancer Letters 213 147-154
Kim JY, Oh KN, Han EH, Kim DH, Jeong TC, Lee ES and Jeong HG (2005) Methoxychlor-induced inducible nitric oxide synthase and proinflammatory cytokines expression in macrophages via NF-kB, ERK, and p38 mitogen-activated protein kinases. Biochemical and Biophysical Research Communications 333 1234-1240
Kim JY, Omori E, Matsumoto K, Nunez G and Ninomiya-Tsuji J (2007) TAK1 is a central mediator of NOD2 signaling in epidermal cells. Journal of Biological Chemistry in press
Kim JY, Park JS, Strassheim D, Douglas I, Diaz Del Valle F, Asehnoune K, Mitra S, Kwak SH, Yamada S, Maruyama I, Ishizaka A and Abraham E (2005) HMGB1 contributes to the development of acute lung injury after hemorrhage. American Joournal of Physiology: Lung Cell and Molecular Physiology 288 L958-L965
Kim JY, Park SJ, Yun KJ, Cho YW, Park HJ and Lee KT (2008) Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kB in RAW 264.7 macrophages. European Journal of Immunology in press
Kim JY and Ro JY (2005) Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells. Scandinavian Journal of Immunology 62 25-35
Kim JY, Yoon YD, Ahn JM, Kang JS, Park SK, Lee K, Song KB, Kim HM and Han SB (2007) Angelan isolated from Angelica gigas Nakai induces dendritic cell maturation through toll-like receptor 4.
International Immunopharmacology 7 78-87
Kim K, Ryu K, Ko Y and Park C (2005) Effects of nuclear factor-kB inhibitors and its implication on natural killer T-cell lymphoma cells. British Journal of Haematology 131 59-66
Kim KA, Choi SK and Choi HS (2004) Corn silk induces nitric oxide synthase in murine macrophages. Exp Mol Med 36 545-550
Kim KA, Shin HH, Choi SK and Choi HS (2005) Corn silk induced cyclooxygenase-2 in murine macrophages. Biosci Biotechnol Biochem 69 1848-1853
Kim K-E, Gu C, Thakur S, Viera E, Lin JC and Rabson AB (2000) Transcriptional regulatory effects of lymphoma-associated NFKB2/lyt10 protooncogenes. Oncogene 19 1334-1345
Kim KIk Kang JH, Chung JK, Lee YJ, Jeong JM, Lee DS and Lee MC (2007) Doxorubicin enhances the expression of transgene under control of the CMV promoter in anaplastic thyroid carcinoma cells.
Journal of Nuclear Medicine in press
Kim KJ, Myung SJ, Hong SS, Lee YJ, Lee SM, Byeon JS, Yang SK, Hong WS, Kim JH and Min YI (2005) Clinical usefulness of glucocorticoid receptor Beta expression and NF-kB activity in patients with ulcerative colitis [Article in Korean]. Korean Journal of Gastroenterology 45 103-110
Kim KM, Choi JY, Yoo SE, Park MY, Lee BS, Ko YH, Sung SH, Shin HM and Park JE (2007) HMCO5, herbal extract, inhibits NF-kB expression in lipopolysaccharide treated macrophages and reduces atherosclerotic lesions in cholesterol fed mice. Journal ofEthnopharmacology in press
Kim KM, Kim PK, Kwon YG, Bai SK, Nam WD and Kim YM (2002) Regulation of apoptosis by nitrosative stress. Journal of Biochemistry and Molecular Biology 35 127-133
Kim KM, Kwon YG, Chung HT, Yun YG, Pae HO, Han JA, Ha KS, Kim TW and Kim YM (2003) Methanol extract of Cordyceps pruinosa inhibits in vitro and in vivo inflammatory mediators by suppressing NF-kB activation. Toxicology and Applied Pharmacology 190 1-8
Kim KM, Pae HO, Zhang M, Ha HY, Ha YA, Cha KY, Cheong YK, Kim JM and Chung HT (2008) Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages. Biomedical Pharmacotherapy in press
Kim KM Song JJ, An JY, Kwon YT and Lee YJ (2005) Pretreatment of acetyl salicylic acid promotes trail-induced apoptosis by downregulating BCL-2 gene expression. Journal of Biological Chemistry 280 41047-41056
Kim KM, Zhang Y, Kim BY, Jeong SJ, Lee SA, Kim GD, Dritschilo A and Jung M (2004) The p65 subunit of nuclear factor-kB is a molecular target for radiation sensitization of human squamous carcinoma cells. Molecular Cancer Therapy 3 693-698
Kim KS, Cho HS, Lee SD, Kim KH, Cho JY, Chung KH, Lee YC, Moon SK and Kim CH (2005) Inhibitory effect of Buthus martensi Karsch extracts on interleukin-1beta-induced expression of nitric oxide (NO) synthase and production of NO in human chondrocytes and LPS-induced NO and prostaglandin E2 production in mouse peritoneal macrophages. Toxicology In Vitro 19 757-769
Kim KS, Park EK, Ju SM, Jung HS, Bang JS, Kim C, Lee YA, Hong SJ, Lee SH, Yang HI and Yoo MC (2007) Taurine chloramine differentially inhibits matrix metalloproteinase 1 and 13 synthesis in interleukin-1beta-stimulated fibroblast-like synoviocytes. Arthritis Research and Therapy 9 R80
Kim KS, Rajagopal V, Gonxalves C, Johnson C and Kalra VK (2006) A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells. Journal of Immunology 177 7211-7224
Kim KW, Cho ML, Kim HR, Ju JH, Park MK, Oh HJ, Kim JS, Park SH, Lee SH and Kim HY (2007) Up-regulation of stromal cell-derived factor 1 (CXCL12) production in rheumatoid synovial fibroblasts through interactions with T lymphocytes: Role of interleukin-17 and CD40L-CD40 interaction. Arthritis and Rheumatism 56 1076-1086
Kim KW, Cho ML, Park MK, Yoon CH, Park SH, Lee SH and Kim HY (2005) Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor kB-dependent pathway in patients with rheumatoid arthritis. Arthritis Research and Therapy 7 R139-R148
Kim KW, Kim BJ, Chung CW, Jo DG, Kim IK, Song YH, Kwon YK, Woo HN and Jung YK (2002) Caspase cleavage product lacking amino-terminus of IkBa sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis. Journal of Cellular Biochemistry 85 334-345
Kim KY, Kim JK, Han SH, Lim JS, Kim KI, Cho DH, Lee MS, Lee JH, Yoon DY, Yoon SR, Chung JW, Choi I, Kim E and Yang Y (2006) Adiponectin is a negative regulator of NK cell cytotoxicity.
Journal of Immunology 176 5958-5964
Kim LK, Choi UY, Cho HS, Lee JS, Lee WB, Kim J, Jeong K, Shim J, Kim-Ha J and Kim YJ (2007) Down-regulation of NF-kB target genes by the AP-1 and STAT complex during the innate immune response in Drosophila. PLoS Biology 5 e238
Kim MH and Joo HG (2007) Immunostimulatory effects of fucoidan on bone marrow-derived dendritic cells. Immunology Letters in press
Kim M, Lee JH, Lee SY, Kim E and Chung J (2006) Caspar, a suppressor of antibacterial immunity in Drosophila. Proceedings of the National Academy ofSciences USA 103 16358-16363
Kim MH, Kim MO, Heo JS, Kim JS and Han HJ (2007) Acetylcholine inhibits long-term hypoxia-induced apoptosis by suppressing the oxidative stress-mediated MAPKs activation as well as regulation of Bcl-2, c-IAPs, and caspase-3 in mouse embryonic stem cells. Apoptosis in press
Kim MH, Kim BT, Min YK and Kim SH (2006) Profiling signalling pathways of the receptor activator of NF-kB ligand-induced osteoclast formation in mouse monocyte cells, RAW264.7. Amino Acids in press
Kim MH, Lee HY, Roh E, Kim BH, Chung EY, Lee YR, Lee IJ, Lee H, Lee CK, Han SB and Kim Y (2008) Novel iminobenzoxathiolone compound inhibits nuclear factor-kB activation targeting inhibitory kB kinase beta and down-regulating interleukin-1b expression in lipopolysaccharide-activated macrophages. Biochemical Pharmacology in press
Kim MH, Park JS, Chang HJ, Baek MK, Kim HR, Shin BA, Ahn BW and Jung YD (2008)Lysophosphatidic acid promotes cell invasion by up-regulating the urokinase-type plasminogen activator receptor in human gastric cancer cells. Journal of Cellular Biochemistry in press
Kim MH, Yoo HS, Kim MY, Jang JH, Baek MK, Kim HR, Kim KK, Shin BA, Ahn BW and Jung YD (2007) Helicobacter pylori stimulates urokinase plasminogen activator receptor expression and cell invasiveness through reactive oxygen species and NF-kB signaling in human gastric carcinoma cells. International Journal of Molecular Medicine 19 689-697
Kim MJ, Han JM, Jin YY, Baek NI, Bang MH, Chung HG, Choi MS, Lee KT, Sok DE and Jeong TS (2008) In vitro antioxidant and anti-inflammatory activities of Jaceosidin from Artemisia princeps Pampanini cv. Sajabal. Archives of Pharmacal Research 31 429-437
Kim MJ, Kim DH, Lee KW, Yoon DY and Surh YJ (2007) Jaceosidin induces apoptosis in ras-transformed human breast epithelial cells through generation of reactive oxygen species. Annals of the New York Academy of Sciences 1095 483-495
Kim MJ, Kim MK and Kang JS (2006) Orientia tsutsugamushi inhibits tumor necrosis factor alpha production by inducing interleukin 10 secretion in murine macrophages.Microbial Pathogenesis 40 1-7
Kim MJ, Ryu GR, Kang JH, Sim SS, Min do S, Rhie DJ, Yoon SH, Hahn SJ, Jeong IK, Hong KJ, Kim MS and Jo YH (2004) Inhibitory effects of epicatechin on interleukin-1beta-induced inducible nitric oxide synthase expression in RINm5F cells and rat pancreatic islets by down-regulation of NF-kB activation. Biochemical Pharmacology 68 1775-1785
Kim MO, Moon DO, Heo MS, Lee JD, Jung JH, Kim SK, Choi YH and Kim GY (2008) Pectenotoxin-2 abolishes constitutively activated NF-kB, leading to suppression of NF-kB related gene products and potentiation of apoptosis. Cancer Letters in press
Kim MO, Suh HS, Brosnan CF and Lee SC (2004) Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta. Journal of Neurochemistry 90 297-308
Kim MO, Suh HS, Si Q, Terman BI and Lee SC (2006) Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia. Journal of Virology 80 62-72
Kim MS, Lim WK, Park RK, Sin T, Yoo YH, Hong SH, An NH and Kim HM (2005) Involvement of mitogen-activated protein kinase and NF-kappaB activation in Ca(2+)-induced IL-8 production in human mast cells. Cytokine 32 226-233
Kim MS, Park MJ, Kim SJ, Lee CH, Yoo H, Shin SH, Song ES and Lee SH (2005) Emodin suppresses hyaluronic acid-induced MMP-9 secretion and invasion of glioma cells.International Journal of Oncology 27 839-846
Kim MY, Anderson G, White A, Jenkinson E, Arlt W, Martensson IL, Erlandsson L and Lane PJ (2005) OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression. Journal of Immunology 174 6686-6691
Kim MY, Song KS, Park GH, Chang SH, Kim HW, Park JH, Jin H, Eu KJ, Cho HS, Kang G, Kim YC and Cho MH (2004) B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kB, AP-1, Nrf2, and osteopontin. Journal of Veterinary Science 5 131-137
Kim ND, Kim EM, Kang KW, Cho MK, Choi SY and Kim SG (2003) Ginsenoside Rg3 inhibits phenylephrine-induced vascular contraction through induction of nitric oxide synthase. British Journal of Pharmacology 140 661-670
Kim ND, Pokharel YR andKang KW (20070 Ginsenoside Rd enhances glutathione levels in H4IIE cells via NF-kB-dependent gamma-glutamylcysteine ligase induction. Pharmazie 62 933-936
Kim NH, Jeon S, Lee HJ and Lee AY (2007) Impaired PI3K/Akt activation-mediated NF-kB inactivation under elevated TNF-a is more vulnerable to apoptosis in vitiliginous keratinocytes. Journal of Investative Dermatology in press
Kim NS, Kim HJ, Koo BK, Kwon MC, Kim YW, Cho Y, Yokota Y, Penninger JM and Kong YY (2006) Receptor activator of NF-kB ligand regulates the proliferation of mammary epithelial cells via Id2. Molecular and Cellular Biology 26 1002-1013
Kim R, Emi M, Tanabe K and Murakami S (2006) Role of the unfolded protein response in cell death. Apoptosis 11 5-13
Kim R, Emi M, Tanabe K, Uchida Y and Toge T (2004) The role of Fas ligand and transforming growth factor beta in tumor progression. Cancer 100 2281-2291
Kim RD, Darling CE, Cerwenka H and Chari RS (2000) Hypoosmotic stress activates p38, ERK 1 and 2, and SAPK/JNK in rat hepatocytes. Journal of Surgical Research 90 58-66
Kim RD, Roth TP, Darling CE, Ricciardi R, Schaffer BK and Chari RS (2001) Hypoosmotic stress stimulates growth in HepG2 cells via protein kinase B-dependent activation of activator protein-1. Journal of Gastrointestinal Surgery 5 546-555
Kim RG, Shin KM, Kim YK, Jeong HJ, Ha J, Choi JW, Park HJ, Lee KT (2003) Inhibition of methanol extract from the aerial parts of Saururus chinensis on lipopolysaccharide-induced nitric oxide and prostagladin E(2) production from murine macrophage RAW 264.7 cells. Biol Pharm Bull 26 481-486
Kim S, Choi K, Kwon D, Benveniste EN and Choi C (2004) Ubiquitin-proteasome pathway as a primary defender against TRAIL-mediated cell death. Cell Mol Life Sci 61 1075-1081
Kim S, Domon-Dell C, Kang J, Chung DH, Freund JN, Evers BM (2004) Down-regulation of the tumor suppressor PTEN by the TNFa /NIK/NF-kB pathway is linked to a default IkB-a autoregulatory loop. Journal of Biological Chemistry 274 4285-4291
Kim S, Domon-Dell C, Wang Q, Chung DH, Di Cristofano A, Pandolfi PP, Freund JN and Evers BM (2002) PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kB-dependent pathway. Gastroenterology 123 1163-1178
Kim S, Fotiadu A and Kotoula V (2005) Increased expression of soluble decoy receptor 3 in acutely inflamed intestinal epithelia. Clinical Immunology 115 286-294
Kim S, Johnson V and Sharma R (2002) Mercury inhibits nitric oxide production but activates proinflammatory cytokine expression in murine macrophage: differential modulation of NF-kB and p38 MAPK signaling pathways. Nitric Oxide 7 67-74
Kim S, Kang S, Kim H and Kim T (2002) Potentiation of 1,25-dihydroxyvitamin D(3)-induced differentiation of human promyelocytic leukemia cells into monocytes by costunolide, a germacranolide sesquiterpene lactone. Biochemical Pharmacology 64 1233-1242
Kim S, La Motte-Mohs RN, Rudolph D, Zuniga-Pflucker JC and Mak TW (2003) The role of nuclear factor-kB essential modulator (NEMO) in B cell development and survival. Proceedings of the National Academy of Sciences USA 100 1203-1208
Kim S, Millet I, Kim HS, Kim JY, Han MS, Lee MK, Kim KW, Sherwin RS, Karin M, and Lee MS (2007) NF-kB prevents beta cell death and autoimmune diabetes in NOD mice.Proceedings of the National Academy of Sciences USA in press
Kim S, Salim AA, Swanson SM and Kinghorn AD (2006) Potential of cyclopenta[b]benzofurans from Aglaia species in cancer chemotherapy. Anticancer Agents in Medicinal Chemistry 6 319-345
Kim S, Yamazaki M, Zella LA, Meyer MB, Fretz JA, Shevde NK and Pike JW (2006) Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D(3). Journal of Steroid Biochemistry and Molecular Biology in press
Kim SB, Kim JS, Lee JH, Yoon WJ, Lee DS, Ko MS, Kwon BS, Choi DH, Cho HR, Lee BJ, Chung DK, Lee HW and Park JW (2006) NF-kB activation is required for cisplatin-induced apoptosis in head and neck squamous carcinoma cells. FEBS Letters 580 311-318
Kim SB, Natori Y, Ozawa T, Umezawa Y and Tao H (2007) A method for determining the activities of cytokines based on the nuclear transport of nuclear factor-kB.Analytical Biochemistry 103 430-434
Kim SC, Tonkonogy SL, Karrasch T, Jobin C and Sartor RB (2007) Dual-association of gnotobiotic Il-10-/- mice with 2 nonpathogenic commensal bacteria induces aggressive pancolitis. Inflammatory Bowel Disease in press
Kim SD, Yang SI, Kim HC, Shin CY and Ko KH (2007) Inhibition of GSK-3beta mediates expression of MMP-9 through ERK1/2 activation and translocation of NF-kB in rat primary astrocyte. Brain Research in press
Kim SG, Cho MK, Choi SH, Kim HJ, Kwak MK and Kim ND (1999) Molecular basis for hepatic detoxifying enzyme induction by 2-(allylthio)pyrazine in rats in comparison with oltipraz: effects on prooxidant production and DNA degradation. Drug Metab Dispos 27 667-673
Kim SG, Kim JS, Kim JM, Jung HC and Song IS (2005) Inhibition of proinflammatory cytokine expression by NF-kB (p65) antisense oligonucleotide in Helicobacter pylori-infected mice. Heliobacter 10 559-566
Kim SH, Choi CH, Kim SY, Eun JS and Shin TY (2005) Anti-allergic effects of Artemisia iwayomogi on mast cell-mediated allergy model. Exp Biol Med (Maywood) 230 82-88
Kim SH, Chu HJ, Kang DH, Song GA, Cho M, Yang US, Kim HJ and Chung HY (2002) NF-kB binding activity and cyclooxygenase-2 expression in persistent CCl(4)-treated rat liver injury. Journal of Korean Medical Science 17 193-200
Kim SH, Gunnery S, Choe JK and Mathews MB (2002) Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR. Oncogene 21 8741-8748
Kim SH, Han SY, Azam T, Yoon DY and Dinarello CA (2005) Interleukin-32: a cytokine and inducer of TNFa. Immunity 22 131-142
Kim SH, Hong KO, Hwang JK and Park KK (2005) Xanthorrhizol has a potential to attenuate the high dose cisplatin-induced nephrotoxicity in mice. Food and Chemical Toxicology 43 117-122
Kim SH, Johnson VJ, Shin TY and Sharma RP (2004) Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-kB signaling pathways. Exp Biol Med (Maywood) 229 203-213
Kim SH, Jun CD, Suk K, Choi BJ, Lim H, Park S, Lee SH, Shin HY, Kim DK and Shin TY (2006) Gallic acid inhibits histamine release and pro-inflammatory cytokine production in mast cells. Toxicological Sciences 91 123-131
Kim SH, Kang YJ, Kim WJ, Woo DK, Lee Y, Kim DI, Park YB, Kwon BS, Park JE and Lee WH (2004) TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages. Circulation Journal 68 396-399
Kim SH, Kim TS, Kim SJ, Seong CN, Lee OH, Lee HJ and Yoo JC (2007) Inhibition of interleukin-12 production in mouse macrophages via suppression of nuclear factor-kB binding activity by Phyllostachys nigra var. henonis. Immunopharmacology andImmunotoxicology 29 131-139
Kim SH, Kim TS, Lee JW, Ha JW, Park NS, Lee HJ and Yoo JC (2007) Inhibition of mouse macrophages interleukin-12 production: suppression of nuclear factor-kB binding activity by a specific factor isolated from Scapharca broughtonii. Archives ofPharmacal Research 30 350-354
Kim SH, Kwon TK and Shin TY (2008) Antiallergic effects of vitis amurensis on mast cell-mediated allergy model. Experimental Biology and Medicine (Maywood) 233 192-199
Kim SH, Oh SM and Kim TS (2005) Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone. European Journal of Pharmacology 511 89-97
Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA and Dinarello CA (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. Journal of Immunology 166 148-154
Kim SH, Shin KJ, Kim D, Kim YH, Han MS, Lee TG, Kim E, Ryu SH and Suh PG (2003) Luteolin inhibits the nuclear factor-kB transcriptional activity in Rat-1 fibroblasts. Biochemical Pharmacology 66 955-963
Kim SH and Shin TY (2005) Amomum xanthiodes inhibit mast cell-mediated allergic reactions through the inhibition of histamine release and inflammatory cytokine production. Experimental Biology and Medicine (Maywood) 230 681-687
Kim SH and Shin TY (2005) Effect of Dracocephalum argunense on mast-cell-mediated hypersensitivity. International Archives of Allergy and Immunology 139 87-95
Kim SH, Song JH, Choi BG, Kim HJ and Kim TS (2006) Chemical modification of santonin into a diacetoxy acetal form confers the ability to induce differentiation of human promyelocytic leukemia cells via the downregulation of NF-kB DNA binding activity.Journal of Biological Chemistry 281 13117-13125
Kim SH, Song SH, Kim SG, Chun KS, Lim SY, Na HK, Kim JW, Surh YJ, Bang YJ and Song YS (2004) Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-kB as a possible target. Journal of Cancer Research and Clinical Oncology 130 551-560
Kim SH, Hwang CI, Juhnn YS, Lee JH, Park WY and SAong YS (2007) GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis 28 223-231
Kim SH, Hwang CI, Park WY, Lee JH and Song YS (2006) GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. Carcinogenesis 27 1961-1969
Kim SH, Lee S, Suk K, Bark H,Jun CD, Kim DK, Choi CH and Yoshimura T (2007) Discoidin domain receptor 1 mediates collagen-induced nitric oxide production in J774A.1 murine macrophages. Free Radical Biology and Medcine 42 343-352
Kim SJ, Choi EY, Cho YJ, Lee JY, Choi JI and Choi IS (2005) Surface-associated material from Porphyromonas gingivalis stimulates the release of nitric oxide by inducing expression of inducible nitric oxide synthase. Microbes and Infection 8 470-477
Kim SJ and Chun JS (2003) Protein kinase Calpha and zeta regulate nitric oxide-induced NF-kB activation that mediates cyclooxygenase-2 expression and apoptosis but not dedifferentiation in articular chondrocytes. Biochemical and Biophysical Research Communications 303 206-211
Kim SJ, Ha MS, Choi EY, Choi JI and Choi IS (2004) Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase. Journal of Periodontal Research 39 424-431
Kim SJ, Ha MS, Choi EY, Choi JI and Choi IS (2005) Nitric oxide production and inducible nitric oxide synthase expression induced by Prevotella nigrescens lipopolysaccharide. FEMS Immunol Med Microbiol 43 51-58
Kim SJ, Hwang SG, Kim IC and Chun JS (2003) Actin cytoskeletal architecture regulates nitric oxide-induced apoptosis, dedifferentiation and cyclooxygenase-2 expression in articular chondrocytes via mitogen-activated protein kinase and protein kinase C pathways. Journal of Biological Chemistry 278 42448-42456
Kim SJ, Jeong HJ, Choi IY, Lee KM, Park RK, Hong SH and Kim HM (2005) Cyclooxygenase-2 inhibitor (SC-236) suppresses NF-kB activation and phosphorylation of p38 MAPK, ERK, and JNK in HMC-1 cells. Journal of Pharmacology & Experimental Therapeutics 314 27-34
Kim SJ, Jeong HJ, Lee KM, Moon PC, Yun JM, Cho KM, Moon BS, Lee HJ, Hong SH, Kim HM and Um JY (2006) The effect of SHJKS on cytokines production and NF-kB activation in the peripheral blood mononuclear cells of patients with cerebral infarction.Immunopharmacology and Immunotoxicology 28 557-570
Kim SJ, Jeong HJ, Lee KM, Myung NY, An NH, Yang WM, Park SK, Lee HJ, Hong SH, Kim HM and Um JY (2007) Epigallocatechin-3-gallate suppresses NF-kB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells. Journal ofNutritional Biochemistry in press
Kim SJ, Jeong HJ, Moon PD, Lee KM, Lee HB, Jung HJ, Jung SK, Rhee HK, Yang DC, Hong SH and Kim HM (2005) Anti-inflammatory activity of gumiganghwaltang through the inhibition of nuclear factor-kB activation in peritoneal macrophages. Biological &Pharmaceutical Bulletin 28 233-237
Kim SJ, Jeong HJ, Moon PD, Lee KM, Lee MG, Moon BS, An NH, Hong SH, Na HJ, Jeon H, Kim HM and Um JY (2006) The anti-inflammatory effect of gigukjiwhangwhangami through the inhibition of nuclear factor-kB activation in the peripheral blood mononuclear cells of patients with cerebral infarction. Biological & Pharmaceutical Bulletin 292251-2255
Kim SJ, Jeong HJ, Park SU, Moon BS, Moon PD, An NH, Lee KM, Hong SH, Kim HM and Um JY (2007) Anti-inflammatory effect of Dohongsamultang through inhibition of nuclear factor-kB activation in peripheral blood mononuclear cells of patients with Cerebral infarction. American Journal of Chinese Medcine 35 415-426
Kim SJ, Kang SY, Shin HH and Choi HS (2005) Sulforaphane inhibits osteoclastogenesis by inhibiting nuclear factor-kB. Molecules and Cells 20 364-370
Kim SJ, Lee EJ, Song YS, Jeong HJ, Lee KM, Kim HR, Chae HJ, Shin TY, Kim YK, Hong SH and Kim HM (2005) Cheongyeolsaseuptang inhibits production of TNF-alpha, IL-6 and IL-8 as well as NF-kB activation in human mast cells. Journal of Ethnopharmacology 97 83-88
Kim SJ, Varghese TK, Zhang Z, Zhao LC, Thomas G, Hummel M and Abecassis M (2005) Renal ischemia/reperfusion injury activates the enhancer domain of the human cytomegalovirus major immediate early promoter. American Journal of Transplantation5 1606-1613
Kim SN, Kim MH, Min YK and Kim SH (2008) Licochalcone A inhibits the formation and bone resorptive activity of osteoclasts. Cell Biology International in press
Kim SN, Son SC, Lee SM, Kim CS, Yoo DG, Lee SK, Hur GM, Park JB and Jeon BH (2006) Midazolam inhibits proinflammatory mediators in the lipopolysaccharide-activated macrophage. Anesthesiology 105 105-110
Kim SO, Chun KS, Kundu JK and Surh YJ (2004) Inhibitory effects of [6]-gingerol on PMA-induced COX-2 expression and activation of NF-kB and p38 MAPK in mouse skin. Biofactors 21 27-31
Kim SO, Kundu JK, Shin YK, Park JH, Cho MH, Kim TY and Surh YJ (2005) [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kB in phorbol ester-stimulated mouse skin. Oncogene 24 2558-2567
Kim SP, Park JW, Lee SH, Lim JH, Jang BC, Lee SH, Jang IH, Freund JN, Suh SI, Mun KC, Song DK, Ha EM, Lee WJ and Kwon TK (2004) Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer. Biochemical and Biophysical Research Communications 315 93-99
Kim SR, Bae YH, Bae SK, Choi SK, Yoon KH, Koo TH, Jang HO, Yun I, Kim KW, Kwon YG, Yoo MA and Bae MK (2008) Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kB activation in endothelial cells. Biochimica et Biophysica Acta in press
Kim SR, Lee KS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Koh GY and Lee YC (2008) Angiopoietin-1 variant, COMP-Ang1 attenuates hydrogen peroxide-induced acute lung injury. Experimental and Molecular Medicine 40 320-331
Kim SR, Lee KS, Park SJ, Min KH, Lee KY, Choe YH, Lee YR, Kim JS, Hong SJ and Lee YC (2007) PTEN down-regulates IL-17 expression in a murine model of toluene diisocyanate-induced airway disease. Journal of Immunology 179 6820-6829
Kim SS, Rhee S, Lee KH, Kim JH, Kim HS, Kang MS and Chung CH (1998) Inhibitors of the proteasome block the myogenic differentiation of rat L6 myoblasts. FEBS Letters 433 47-50
Kim SW, Choi SC, Choi EY, Kim KS, Oh JM, Lee HJ, Oh HM, Kim S, Oh BS, Kimm KC, Lee MH, Seo GS, Kim TH, Oh HC, Woo WH, Kim YS, Pae HO, Park DS, Chung HT and Jun CD (2004) Catalposide, a compound isolated from Catalpa ovata, attenuates induction of intestinal epithelial proinflammatory gene expression and reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice. Inflammatory Bowel Disease 10 564-572
Kim SW, Oleksyn DW, Rossi RM, Jordan CT, Sanz I, Chen L and Zhao J (2007) Protein kinase C-associated kinase PKK is required for NF-kB signaling and survival in diffuse large B-cell lymphoma cells. Blood in press
Kim SY (2006) Transglutaminase 2 in inflammation. Frontiers in Bioscience 11 3026-3035
Kim SY, Kim DH, Han SJ, Hyun JW and Kim HS (2007) Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells.Biochemical Pharmacology in press
Kim SY, Kim SH, Shin HY, Lim JP, Chae BS, Park JS, Hong SG, Kim MS, Jo DG, Park WH and Shin TY (2007) Effects of Prunella vulgaris on mast cell-mediated allergic reaction and inflammatory cytokine production. Experimental Biology and Medicine (Maywood) 232 921-926
Kim SY, Lee YC, Kim HK and Blaser MJ (2006) Helicobacter pylori CagA transfection of gastric epithelial cells induces interleukin-8. Cellular Microbiology 8 97-106
Kim SY, Lee EJ, Woo MS, Jung JS, Hyun JW, Min SW, Kim DH and Kim HS (2007) Inhibition of matrix metalloproteinase-9 gene expression by an isoflavone metabolite, irisolidone in U87MG human astroglioma cells. Biochemical Biophysical Research Communications in press
Kim T, Handa A, Iida J and Yoshida S (2007) RANKL expression in rat periodontal ligament subjected to a continuous orthodontic force. Archives of Oral Biology 52 244-250
Kim T, Yoon J, Cho H, Lee WB, Kim J, Song YH, Kim SN, Yoon JH, Kim-Ha J and Kim YJ (2005) Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kB signaling modules. Nature Immunolology 6 211-218
Kim TB, Kim SY, Moon KA, Park CS, Jang MK, Yun ES, Cho YS, Moon HB and Lee KY (2007) Five-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates poly (I:C)-induced airway inflammation in a murine model of asthma. Clinical and ExperimentalAllergy in press
Kim TH, Stone MA, Rahman P, Yoo DH, Park YW, Payne U, Hallett D and Inman RD (2005) Interleukin 1 and nuclear factor-kB polymorphisms in ankylosing spondylitis in Canada and Korea. Journal of Rheumatology 32 1907-1910
Kim TI, Jin SH, Kang EH, Shin SK, Choi KY and Kim WH (2002) The role of mitogen-activated protein kinases and their relationship with NF-kB and PPARgamma in indomethacin-induced apoptosis of colon cancer cells. Annals of the New York Academy of Sciences USA 973 241-245
Kim TK and Maniatis T (1997) The mechanism of transcriptional synergy of an in vitro assembled interferon-b enhanceosome. Molecular Cell 1 119-128
Kim WH, CHoi CH, Kang SK, Kwon CH and Kim YK (2005) Ceramide induces non-apoptotic cell death in human glioma cells. Neurochemistry Research 30 969-979
Kim WH, Hong F, Jaruga B, Hu Z, Fan S, Liang TJ and Gao B (2001) Additive activation of hepatic NF-kB by ethanol and HBX or HCV core protein: involvement of TNF-a receptor I-independent and -dependent mechanisms. FASEB Journal 15 2551-2553
Kim WJ, Back SH, Kim V, Ryu I and Jang SK (2005) Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions. Molecular and Cellular Biology 25 2450-2562
Kim WJ, Bae EM, Kang YJ, Bae HU, Hong SH, Lee JY, Park JE, Kwon BS, Suk K and Lee WH (2006) Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques. Immunology 119 421-429
Kim W-K and Baluda MA (1988) Proto-oncogene expression in chicken leukemic cells induced by avian myeloblastosis virus. Oncogene Research 3 147-154
Kim WK, Hwang SY, Oh ES, Piao HZ, Kim KW and Han IO (2004) TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity. Journal of Immunology 172 7015-7023
Kim WK, Jang PG, Woo MS, Han IO, Piao HZ, Lee K, Lee H, Joh TH and Kim HS (2004) A new anti-inflammatory agent KL-1037 represses proinflammatory cytokine and inducible nitric oxide synthase (iNOS) gene expression in activated microglia. Neuropharmacology 47 243-252
Kim Y, Moon JS, Lee KS, Park SY, Cheong J, Kang HS, Lee HY and Kim HD (2004) Ca(2+)/calmodulin-dependent protein phosphatase calcineurin mediates the expression of iNOS through IKK and NF-kB activity in LPS-stimulated mouse peritoneal macrophages and RAW 264.7 cells. Biochemical and Biophysical Research Communications 314 695-703
Kim Y, Suh N, Sporn M and Reed JC (2002) An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis. Journal of Biological Chemistry 277 22320-22329
Kim YA, Lee WH, Choi TH, Rhee SH, Park KY and Choi YH (2003) Involvement of p21WAF1/CIP1, pRB, Bax and NF-kB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells. International Journal of Oncology 23 1143-1149
Kim YA, LIm SY, Rhee SH, Park KY, Kim CH, Choi BT, Lee SJ, Park YM and Choi YH (2006) Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in beta-amyloid-treated C6 glioma cells. International Journal of Molecular Medicine 17 1069-1075
Kim YD, An SC, Oyama T, Kawamoto T and Kim H (2003) Oxidative stress, hogg1 expression and NF-kB activity in cells exposed to low level chromium. Journal of Occupational Health 45 271-277
Kim YG, Ohta T, Takahashi T, Kushiro A, Nomoto K, Yokokura T, Okada N and Danbara H (2006) Probiotic Lactobacillus casei activates innate immunity via NF-kB and p38 MAP kinase signaling pathways.
Microbes and Infection 8 994-1005
Kim YH, Choi KH, Park JW and Kwon TK (2005) LY294002 inhibits LPS-induced NO production through a inhibition of NF-kB activation: independent mechanism of phosphatidylinositol 3-kinase. Immunology Letters 99 45-50
Kim YH, Kim JM, Kim SN, Kim GS and Baek JH (2003) p44/42 MAPK activation is necessary for receptor activator of nuclear factor-kB ligand induction by high extracellular calcium. Biochemical and Biophysical Research Communications 304 729-735
Kim YH, Lee SH, Lee JY, Choi SW, Park JW and Kwon TK (2004) Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-kB and c-Jun NH(2)-terminal kinase. European Journal of Pharmacology 494 1-9
Kim YH, Woo KJ, Lim JH, Kim S, Lee TJ, Jung EM, Lee JM, Park JW and Kwon TK (2005) 8-Hydroxyquinoline inhibits iNOS expression and nitric oxide production by down-regulating LPS-induced activity of NF-kB and C/EBPb in Raw 264.7 cells. Biochemical and Biophysical Research Communications 329 591-597
Kim YI, Park JE, Martinez-Hernandez A and Yi AK (2008) CpG DNA prevents liver injury and shock-mediated death by modulating expression of IL-1R-associated kinases. Journal of Biological Chemistry in press
Kim YJ, Hwang SY and Han IO (2006) Insoluble matrix components of glioma cells suppress LPS-mediated iNOS/NO induction in microglia.
Biochemical and Biophysical Research Communications 347 731-738
Kim YJ, Hwang SY, Hwang JS, Lee JW, Oh ES and Han IO (2007) C6 gioma cell insoluble matrix components enhance IFN-g-stimulated INOS/no production in BV2 microglial cells. Journal of Biological Chemistry in press
Kim YJ, Hwang SY, Oh ES, Oh S and Han IO (2006) IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kB pathways. Journal of Neuroscience Research 84 1037-1046
Kim YJ, Rossa C and Kirckwood KL (2005) Prostaglandin production by human gingival fibroblasts inhibited by triclosan in the presence of cetylpyridinium chloride. Journal of Peridontology 76 1735-1742
Kim YJ, Yu JM, Joo HJ, Kim HK, Cho HH, Bae YC and Jung JS (2007) Role of CD9 in proliferation and proangiogenic action of human adipose-derived mesenchymal stem cells. Pflugers Archiv in press
Kim YK, Bourgeois CF, Pearson R, Tyagi M, West MJ, Wong J, Wu SY, Chiang CM and Karn J (2006) Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency. EMBO Journal 25 3596-3604
Kim YK, Lee EK, Kang JK, Kim JA, You JS, Park JH, Seo DW, Hwang JW, Kim SN, Lee HY, Lee HW and Han JW (2006) Activation of NF-kB by HDAC inhibitor apicidin through Sp1-dependent de novo protein synthesis: its implication for resistance to apoptosis.Cell Death and Differentiation 13 2033-2041
Kim YK, Seo DW, Kang DW, Lee HY, Han JW and Kim SN (2006) Involvement of HDAC1 and the PI3K/PKC signaling pathways in NF-kB activation by the HDAC inhibitor apicidin.Biochemical and Biophysical Research Communications 347 1088-1093
Kim YM, Cao D, Reed W, Wu W, Jaspers I, Tal T, Bromberg PA and Samet JM (2007) Zn(2+)-induced NF-kB-dependent transcriptional activity involves site-specific p65/RelA phosphorylation. Cellular Signaling 19 538-546
Kim YM and Paik SG (2005) Induction of expression of inducible nitric oxide synthase by Taxol in murine macrophage cells. Biochemical and Biophysical Research Communications 326 410-416
Kim YM, Reed W, Lenz AG, Jaspers I, Silbajoris R, Nick HS and Samet JM (2005) Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells. American Journal of Physiology: Lung Cell and Molecular Physiology 288 L432-L441
Kim YS, Ahn Y, Hong MH, Joo SY, Kim KH, SOhn IS, Park HW, Hong YJ, Kim JH, Kim W, Jeong MH, Cho JG, Park JC and Kang JC (2007) Curcumin attenuates inflammatory responses of TNF-a-stimulated human endothelial cells. Journal of Cardiovascular Pharmacology 50 41-49
Kim YS, Ahn Y, Hong MH, Kim KH, Park HW, Hong YJ, Kim JH, Kim W, Jeong MH, Cho JG, Park JC and Kang JC (2007) Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and nuclear factor-kB in endothelial cells.
Journal of Cardiovascular Pharmacology 49 376-383
Kim YS, Cho K-O, Lee HJ, Kim SY, Sato Y and Cho Y-J (2006) Down Syndrome ccandidate region 1 increases the stability of the IkBa protein: implications for its anti-inflammatory effects. Journal of Biological Chemistry 281 39051-39061
Kim YS, Han CY, Kim SW, Kim JH, Lee SK, Jung DJ, Park SY, Kang H, Choi HS, Lee JW and Pak YK (2001) The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7. Journal of Biological Chemistry 276 33736-33740
Kim YS, Han SJ, Ryu JH, Choi KH, Hong YS, Chung YH, Perrot S, Raibaud A, Brey PT and Lee WJ (2000) Lipopolysaccharide-activated kinase, an essential component for the induction of the antimicrobial peptide genes in Drosophila melanogaster cells. Journal of Biological Chemistry 275 2071-2079
Kim YS, Kim JS, Jung HC and Song IS (2004) The effects of thalidomide on the stimulation of NF-kB activity and TNF-a production by lipopolysaccharide in a human colonic epithelial cell line. Molecules and Cells 17 210-216
Kim YS, Kim SS, Cho JJ, Choi DH, Hwang O, Shin DH, Chun HS, Beal MF and Joh TH (2005) Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia. Journal of Neuroscience 25 3701-3711
Kim YS and Milner JA (2005) Targets for indole-3-carbinol in cancer prevention. Journal of Nutritional Biochemistry 16 65-73
Kim YS, Nedospasov SA and Liu ZG (2005) TRAF2 plays a key, nonredundant role in LIGHT-lymphotoxin beta receptor signaling. Molecular and Cellular Biology 25 2130-2137
Kim YS, Schwabe RF, Qian T, Lemasters JJ and Brenner DA (2002) TRAIL-mediated apoptosis requires NF-kB inhibition and the mitochondrial permeability transition in human hepatoma cells. Hepatology 36 1498-1508
Kim YW, Zhao RJ, Park SJ, Lee JR, Cho IJ, Yang CH, Kim SG and Kim SC (2008) Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-kB-dependent iNOS and proinflammatory cytokines production. British Journal of Pharmacology in press
Kim do Y, Jun JH, Lee HL, Woo KM, Ryoo HM, Kim GS, Baek JH and Han SB (2007) N-acetylcysteine prevents LPS-induced pro-inflammatory cytokines and MMP2 production in gingival fibroblasts. Archives of Pharmacal Research 30 1283-1292
Kimbrell MR, Warshakoon H, Cromer JR, Malladi S, Hood JD, Balakrishna R, Scholdberg TA and David SA (2008) Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells. Immunology Letters in press
Kimura A, Ohmichi M, Kawagoe J, Kyo S, Mabuchi S, Takahashi T, Ohshima C, Arimoto-Ishida E, Nishio Y, Inoue M, Kurachi H, Tasaka K and Murata Y (2004) Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines. Oncogene 23 4505-4515
Kimura H, Inukai Y, Takii T, Furutani Y, Shibata Y, Hayashi H, Sakurada S, Okamoto T, Inoue J, Oomoto Y and Onozaki K (1998) Molecular analysis of constitutive IL-1alpha gene expression in human melanoma cells: autocrine stimulation through NF-kB activation by endogenous IL-1alpha. Cytokine 10 872-879
Kimura K and Gelmann EP (2002) Propapoptotic effects of NF-kB in LNCaP prostate cancer cells lead to serine protease activation. Cell Death & Differentiation 9 972-980
Kimura K, Bowen C, Spiegel S and Gelmann EP (1999) Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis. Cancer Research 59 1606-1614
Kimura M, Haisa M, Uetsuka H, Takaoka M, Ohkawa T, Kawashima R, Yamatsuji T, Gunduz M, Kaneda Y, Tanaka N and Naomoto Y (2003) TNF combined with IFN-alpha accelerates NF-kB-mediated apoptosis through enhancement of Fas expression in colon cancer cells. Cell Death & Differentiation 10 718-728
Kimura K, Markowski M, Bowen C and Gelmann EP (2001) Androgen blocks apoptosis of hormone-dependent prostate cancer cells. Cancer Research 61 5611-5618
Kimura K, Nagaki M, Kaimi K, Saio M, Saeki T, Okuda Y, Kuwata K and Moriwaki H (2008) Critical role of CD44 in hepatotoxin-mediated liver injury. Journal of Hepatology in press
Kimura K, Nagaki M, Takai S, Satake S and Moriwaki H (2004) Pivotal role of nuclear factor kB signaling in anti-CD40-induced liver injury in mice. Hepatology 40 1180-1189
Kimura K, Teranishi S, Fukuda K, Kawamoto K and Nishida T (2008) Delayed disruption of barrier function in cultured human corneal epithelial cells induced by tumor necrosis factor-a in a manner dependent on NF-kB. INvestigative Ophthalmology and Visual Science 49 565-571
Kimura MY, Hosokawa H, Yamashita M, Hasegawa A, Iwamura C, Watarai H, Taniguchi M, Takagi T, Ishii S and Nakayama T (2005) Regulation of T helper type 2 cell differentiation by murine Schnurri-2. Journal of Experimental Medicine 201 397-408
Kimura MY, Iwamura C, Suzuki A, Miki T, Hasegawa A, Sugaya K, Yamashita M, Ishii S and Nakayama T (2007) Schnurri-2 controls memory Th1 and th2 cell numbers in vivo.Journal of Immunology 178 4926-4936
Kimura N, Miyakawa Y, Kohmura K, Umezawa K, Ikeda Y and Kizaki M (2007) Targeting NF-kB and induction of apoptosis by novel NF-kappaB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) in Burkitt lymphoma cells. Leukemia Research in press
Kimura T, Nakamura H,Koyama S, Ogita K, Tabata C, Tsutsui T, Shimoya K, Koyama M, Kaenda Y and Murata Y (2005) In vivo gene transfer into the mouse uterus: A powerful tool for investigating implantation physiology. Journal of Reporductive Immunology 67 13-20
Kimura T, Nakamura H, Ogita K, Koyama S, Tomiie M, Yoshida S, Tsutsui T, Shimoya K, Koyama M and Murata Y (2004) Effect of proteasome pathway on initiation of mouse labor induced by antiprogesterone. American Journal of Reproductive Immunology 52 317-322
Kimura T, Sakaida I, Terai S, Matsumura Y, Uchida K and Okita K (1997) Inhibition of tumor necrosis factor-a production retards liver regeneration after partial hepatectomy in rats. Biochemical and Biophysical Research Communications 231 557-560
Kimura YN, Watari K, Fotovati A, Hosoi F, Yasumoto K, Izumi H, Kohno K, Umezawa K, Iguchi H, Shirouzu K, Takamori S, Kuwano M and Ono M (2007) Inflammatory stimuli from macrophages and cancer cells synergistically promote tumor growth and angiogenesis. Cancer Science 98 2009-2018
Kin H, Wang NP, Mykytenko J, Reeves J, Deneve J, Jiang R, Zatta AJ, Guyton RA, Vinten-Johansen J and Zhao ZQ (2008) Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kB translocation and TNFa release. Shock 29 761-768
Kin NW and Sanders VM (2006) CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase Cgamma2/protein kinase Calphabeta signaling pathways. Journal of Immunology 176 6727-6735
King AE, Critchley HO and Kelly RW (2001) The NF-kB pathway in human endometrium and first trimester decidua. Molecular Human Reproduction 7 175-183
King DJ, Bassett SE, Li X, Fennewald SA, Herzog NK, Luxon BA Shope R and Gorenstein DG (2002) Combinatorial selection and binding of phosphorothioate aptamers targeting human NF-kB RelA(p65) and p50. Biochemistry 41 9696-9706
King KE, Ponnamperuma RM, Allen C, Lu H, Duggal P, Chen Z, Van Waes C and Weinberg WC (2008) The p53 homologue DeltaNp63alpha interacts with the nuclear factor-kB pathway to modulate epithelial cell growth. Cancer Resarch 68 5122-5131
King NJ and Kesson AM (2003) Interaction of flaviviruses with cells of the vertebrate host and decoy of the immune response. Immunol Cell Biol 81 207-216
King NJ, Shrestha B and Kesson AM (2003) Immune modulation by flaviviruses. Advances in Virus Research 60 121-155
King TA, Ghazaleh RA, Juhn SK, Adams GL and Ondrey FG (2005) Induction of heat shock protein 70 inhibits NF-kB in squamous cell carcinoma. Otolaryngol Head Neck Surgery133 70-79
Kingman S (1995) Do variants of cytokine genes help explain autoimmunity? Journal of NIH Research 7 35-36
Kiningham KK, Cardozo ZA, Cook C, Cole MP, Stewart JC, Tassone M, Coleman MC and Spitz DR (2008) All-trans-retinoic acid induces manganese superoxide dismutase in human neuroblastoma through NF-kB. Free Radical Biology and Medicine in press
Kiningham KK, Daosukho C and St Clair DK (2004) IkB-a identified as labile repressor of manganese superoxide dismutase (MnSOD) expression. Biochemical Journal 384 543-549
Kiningham KK, Xu Y, Daosukho C, Popova B and St Clair DK (2001) Nuclear factor kB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2. Biochemical Journal 353 147-156
Kinoshita T, Kondoh C, Hasegawa M, Imamura R and Suda T (2006) Fas-associated factor 1 is a negative regulator of PYRIN-containing Apaf-1-like protein 1. InternationalImmunology in press
Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M and Yoshimura A (2002)
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 17 583-591
Kino T and Chrousos GP (2003) Tumor necrosis factor alpha receptor-and Fas-associated FLASH inhibits transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators. Journal of Biological Chemistry 278 3023-3029
Kino T, Slobodskaya O, Pavlakis GN and Chrousos GP (2002) Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex. Journal of Biological Chemistry 277 2396-2405
Kinoshita K, Sato K, Hori M, Ozaki H and Karaki H (2003) Decrease in the activity of the L-type Ca2+ -channels and its reversal by NF-kB inhibitors in colonic smooth muscle isolated from a TNBS-induced colitis model rat. American Journal of Physiology: Gastrointestinal and Liver Physiology 285 G483-G493
Kinoshita D, Hirota F, Kaisho T, Kasai M, Izumi K, Bando Y, Mouri Y, Matsushima A, Niki S, Han H, Oshikawa K, Kuroda N, Maegawa M, Irahara M, Takeda K, Akira S and Matsumoto M (2006) Essential role of IkB Kinase alpha in thymic organogenesis required for the establishment of self-tolerance. Journal of Immunology 176 3995-4002
Kinoshita T, Wang Y, Hasegawa M, Imamura R and Suda T (2005) PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. Journal of Biological Chemistry 280 21720-21725
Kirch HC, Flaswinkel S, Rumpf H, Brockmann D and Esche H (1999) Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kB and Myc/Max. Oncogene 18 2728-2738
Kirchhoff S, Wilhelm D, Angel P and Hauser H (1999) NFkB activation is required for interferon regulatory factor-1-mediated interferon beta induction. European Journal of Biochemistry 261 546-554
Kirchner D, Duyster J, Ottmann O, Schmid RM, Bergmann L and Munzert G (2003) Mechanisms of Bcr-Abl-mediated NF-kB/Rel activation. Experimental Hematology 31 504-511
Kirchner EA, Mols G, Hermle G, Muehlschlegel JD, Geiger KK, Guttmann J and Pahl HL (2005) Reduced activation of immunomodulatory transcription factors during positive end-expiratory pressure adjustment based on volume-dependent compliance in isolated perfused rabbit lungs. British Journal of Anaesthesiology 94 530-535
Kiriakidis S, Andreakos E, Monaco C, Foxwell B, Feldmann M and Paleolog E (2003) VEGF expression in human macrophages is NF-kB-dependent: studies using adenoviruses expressing the endogenous NF-kB inhibitor IkBa and a kinase-defective form of the IkB kinase 2. Journal of Cell Science 116 665-674
Kirillova I, Chaisson M and Fausto N (1999) Tumor necrosis factor induces DNA replication in hepatic cells through nuclear factor kB activation. Cell Growth & Differentiation 10 819-828
Kirito K, Watanabe T, Sawada K, Endo H, Ozawa K and Komatsu N (2001) Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways. Journal of Biological Chemistry 277 8329-8337
Kiritoshi S, Nishikawa T, Sonoda K, Kukidome D, Senokuchi T, Matsuo T, Matsumura T, Tokunaga H, Brownlee M and Araki E (2003) Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 52 2570-2577
Kirov N, Childs S, O’Connor M and Rushlow C (1994) The Drosophila dorsal morphogen represses the tolloid gene by interacting with a silencer element. Molecular and Cellular Biology 14 713-722
Kirov N, Zhelnin, Shah J and Rushlow C (1993) Conversion of a silencer into an enhancer: evidence for a co-repressor in dorsal-mediated repression in Drosophila. EMBO Journal 12 3193-3199
Kirsch BM, Zeyda M, Stuhlmeier K, Grisar J, Smolen JS, Watschinger B, Stulnig TM, Horl WH, Zlabinger GJ and Saemann MD (2005) The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function. Arthritis Research Therapy 7 R694-R703
Kirstein L, Cvekl A, Chauhan BK and Tamm ER (2000) Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: role of upstream stimulatory factor. Genes Cells 5 661-676
Kis A, Yellon DM and Baxter GF (2003) Role of nuclear factor-kB activation in acute ischaemia-reperfusion injury in myocardium. British Journal of Pharmacology 138 894-900
Kis K, Bodai L, Polyanka H, Eder K, Pivarcsi A, Duda E, Soos G, Bata-Csorgo Z and Kemeny L (2006) Budesonide, but not tacrolimus, affects the immune functions of normal human keratinocytes.
International Immunopharmacology 6 358-368
Kishida A, Matsuyama T, Kitajima I, Maruyama I and Akashi M (2001) Study of cell-material interaction by estimating NF-kB activation in HeLa S3 cells adhered onto hydrophilic substrates. Biomaterials 22 541-546
Kishida O, Miyazaki Y, Murayama Y, Ogasa M, Miyazaki T, Yamamoto T, Watabe K, Tsutsui S, Kiyohara T, Shimomura I and Shinomura Y (2004) Gefitinib (“Iressa”, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. Cancer Chemotherapy and Pharmacology 55 393-403
Kishida S, Sanjo H, Akira S, Matsumoto K and Ninomiya-Tsuji J (2005) TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway. Genes Cells 10 447-454
Kishida Y, Yoshikawa H and Myoui A (2007) Parthenolide, a natural inhibitor of nuclear factor-kB, inhibits lung colonization of murine osteosarcoma cells. ClinicalCancer Research 13 59-67
Kishikawa H, Miura S, Yoshida H, Hirokawa M, Nakamizo H, Higuchi H, Adachi M, Nakatsumi RC, Suzuki H, Saito H and Ishii H (2002) Transmural pressure induces IL-6 secretion by intestinal epithelial cells. Clinical and Experimental Immunology 129 86-91
Kishimoto A, Fujita T, Shiba H, Komatsuzawa H, Takeda K, Kaiya M, Hayashida K, Kawaguchi H and Kurihara H (2008) Irsogladine maleate abolishes the increase in interleukin-8 levels caused by outer membrane protein 29 from Aggregatibacter (Actinobacillus) actinomycetemcomitans through the ERK pathway in human gingival epithelial cells. Journal of Periodontal Research in press
Kishimoto K, Matsumoto K and Ninomiya-Tsuji J (2000) TAK1 mitogen-activated protein kinase is activated by autophosphorylation within its activation loop. Journal of Biological Chemistry 275 7359-7364
Kishimoto M, Yoshimura A, Naito M, Okamoto K, Yamamoto K, Golenbock DT, Hara Y and Nakayam K (2006) Gingipains inactivate a cell surface ligand on Porphyromonas gingivalis that induces TLR2-and TLR4-independent signaling. Microbiology andImmunology 50 315-325
Kishore N, Sommers C, Mathialagan S, Guzova J, Yao M, Hauser S, Huynh K, Bonar S, Mielke C, Albee L, Weier R, Graneto M, Hanau C, Perry T and Tripp CS (2003) A selective IKK-2 inhibitor blocks NF-kB-dependent gene expression in IL-1beta stimulated synovial fibroblasts. Journal of Biological Chemistry 278 32861-32871
Kishore R, Hill JR, McMullen MR, Frenkel J and Nagy LE (2002) ERK1/2 and Egr-1 contribute to increased TNF-alpha production in rat Kupffer cells after chronic ethanol feeding. American Journal of Physiology: Gastrointestinal Liver Physiology 282 G6-G15
Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D and Schmidt AM (1999) N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. Journal of Biological Chemistry 274 31740-31749
Kislinger T, Tanji N, Wendt T, Qu W, Lu Y, Ferran LJ, Jr., Taguchi A, Olson K, Bucciarelli L, Goova M, Hofmann MA, Cataldegirmen G, D’Agati V, Pischetsrieder M, Stern DM and Schmidt AM (2001) Receptor for advanced glycation end products mediates inflammation and enhanced expression of tissue factor in vasculature of diabetic apolipoprotein E-null mice. Arterioscler Thromb Vasc Biol 21 905-910
Kispert A and Herrmann BG (1993) The Brachyury gene encodes a novel DNA binding protein. EMBO Journal 12 3211-3220
Kiss DL, Xu W, Gopalan S, Buzanowska K, Wilczynska KM, Rydel RE and Kordula T (2005) Duration of alpha-antichymotrypsin gene activation by interleukin-1 is determined by efficiency of inhibitor of nuclear factor kBa resynthesis in primary human astrocytes. Journal of Neurochemistry 92 730-738
Kiss K, Kiss J, Rudolf E, Cervinka M nad Szeberenyi J (2004) Sodium salicylate inhibits NF-kB and induces apoptosis in PC12 cells. Journal of Biochemical and Biophysical Methods 61 229-240
Kisseleva T, Song L, Vorontchikhina M, Feirt N, Kitajewski J and Schindler C (2006) NF-kB regulation of endothelial cell function during LPS-induced toxemia and cancer.Journal of Clinical Investigation in press
Kistler B, Rolink A, Marienfeld R, Neumann M and Wirth T (1998) Induction of nuclear factor-kB during primary B cell differentiation. Journal of Immunology 160 2308-2317
Kitada S, Pedersen IM, Schimmer AD and Reed JC (2002) Dysregulation of apoptosis genes in hematopoietic malignancies. Oncogene 21 3459-3474
Kitagawa K, Hamada Y, Kato Y, Nakai K, Nishizawa M, Ito S and Okumura T (2004) Epidermal growth factor and interleukin-1{beta} stimulate synergistically the production of nitric oxide in rat intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol in press
Kitajima I (2007) Development of molecular pathology analysis testing which can be practiced in the hospital laboratory. The clinical application of a transcription factor activation test [Article in Japanese]. Rinsho Byori 55 262-271
Kitajima I, Shinohara T, Bilakovics J, Brown DA, Xu X and Nereneberg M (1992) Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kB. Science 258 1792-1795
Kitajima I, Unoki K and Maruyama I (1999) Phosphorothioate oligodeoxynucleotides inhibit basic fibroblast growth factor-induced angiogenesis in vitro and in vivo. Antisense Nucleic Acid Drug Development 9 233-239
Kitamoto S, Egashira K, Kataoka C, Koyanagi M, Katoh M, Shimokawa H, Morishita R, Kaneda Y, Sueishi K and Takeshita A (2000) Increased activity of nuclear factor-kB participates in cardiovascular remodeling induced by chronic inhibition of nitric oxide synthesis in rats. Circulation 102 806-812
Kitamura C, Nishihara T, Ueno Y, Chen KK, Morotomi T, Yano J, Nagayoshi M and Terashita M (2006) Effects of sequential exposure to lipopolysaccharide and heat stress on dental pulp cells.
Journal of Cellular Biochemistry in press
Kitamura H, Kanehira K, Shiina T, Morimatsu M, Jung BD, Akashi S and Saito M (2002) Bacterial lipopolysaccharide induces mRNA expression of an IkB MAIL through toll-like receptor 4. Journal of Veterinary Medical Science 64 419-422
Kitamura H, Matsushita Y, Iwanaga T, Mori K, Kanehira K, Fujikura D, Morimatsu M and Saito M (2003) Bacterial lipopolysaccharide-induced expression of the IkappaB protein MAIL in B-lymphocytes and macrophages. Archives of Histology and Cytology 66 53-62
Kitamura M (1999) NF-kB-mediated self defense of macrophages faced with bacteria. European Journal of Immunology 29 1647-1655
Kitamura M (2000) Adoptive transfer of nuclear factor-kB-inactive macrophages to the glomerulus. Kidney International 57 709-716
Kitamura T, Sekimata M, Kikuchi S and Homma Y (2005) Involvement of poly(ADP-ribose) polymerase 1 in erbB2 expression in rheumatoid synovial cells. American Journal Physiology: Cell Physiology 289 C82-C88
Kitano A, Saika S, Yamanaka O, Ikeda K, Okada Y, Shirai K and Reinach PS (2007) Emodin suppression of ocular surface inflammatory reaction. InvestigativeOphthalmology & Visual Science 48 5013-5022
Kitaoka Y, Kitaoka Y, Kwong JM, Ross-Cisneros FN, Wang J, Tsai RK, Sadum AA and Lam TT (2006) TNF-alpha-induced optic nerve degeneration and nuclear factor-kB p65.Investigative Ophthalmology and Vision Science 47 1448-1457
Kitaoka Y, Kumai T, Kitaoka Y, Lam TT, Munemasa Y, Isenoumi K, Motoki M, Kuribayashi K, Kogo J, Kobayashi S and Ueno S (2004) Nuclear factor-kB p65 in NMDA-induced retinal neurotoxicity. Brain Research Molecular Brain Research 131 8-16
Kitaoka Y, Munemasa Y, Nakazawa T and Ueno S (2007) NMDA-induced interleukin-1beta expression is mediated by nuclear factor-kB p65 in the retina. Brain Research in press
Kitatani K, Akiba S and Sato T (2004) Ceramide-induced enhancement of secretory phospholipase A(2) expression via generation of reactive oxygen species in tumor necrosis factor-alpha-stimulated mesangial cells. Cell Signaling 16 967-974
Kitaura H, Sands MS, Aya K, Zhou P, Hirayama T, Uthgenannt B, Wei S, Takeshita S, Novack DV, Silva MJ, Abu-Amer Y, Ross FP and Teitelbaum SL (2004) Marrow stromal cells and osteoclast precursors differentially contribute to TNF-a-induced osteoclastogenesis in vivo. Journal of Immunology 173 4838-4846
Kitaura H, Zhou P, Kim HJ, Novack DV, Ross FP and Teitelbaum SL (2005) M-CSF mediates TNF-induced inflammatory osteolysis. Journal of Clinical Investigation 115 3418-3427
Kitamei H, Iwabuchi K, Namba K, Yoshida K, Yanagawa Y, Kitaichi N, Kitamura M, Ohno S and Onoe K (2006) Amelioration of experimental autoimmune uveoretinitis (EAU) with an inhibitor of nuclear factor-kB (NF-kB), pyrrolidine dithiocarbamate. Journal ofLeukoctye Biology 79 1193-1201
Kitazawa M, Nakano T, Chuujou H, Shiojiri E, Iwasaki K and Sakamoto K (2002) Intracellular redox regulation by a cystine derivative suppresses UV-induced NF-kB activation. FEBS Letters 526 106
Kitazawa M, Shibata Y, Hashimoto S, Ohizumi Y and Yamakuni T (2006) Proinsulin C-peptide stimulates a PKC/IkB/NF-kB signaling pathway to activate COX-2 gene transcription in Swiss 3T3 fibroblasts.
Journal of Biochemistry (Tokyo) 139 1083-1088
Kitawawa R and Kitazawa S (2006) Methylation status of a single CpG locus 3 bases upstream of TATA-box of RANKL gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis. Molecular Endocrinology in press
Kitazawa S and Kitazawa R (2002) Epigenetic control of mouse receptor activator of NF-kB ligand gene expression. Biochemical and Biophysical Research Communications 293 126-131
Kitson J, Raven T, Jiang Y-P, Goeddel DV, Giles KM, Pun K-T, Grinham CJ, Brown R and Farrow SN (1996) A death-domain-containing receptor that mediates apoptosis. Nature 384 372-375
Kittaka A, Kuze T, Asakura T, Ito K, Miyasaka T and Inoue J (1998) Oligonucleotides bearing 5-formyl-2′-O-methyluridine: preference in binding affinity to the NF-kB (p50)2 homo- and p50/p65 heterodimers. Bioorganic Medicinal Chemistry Letters 8 3207-3210
Kittaka N, Takemasa I, Takeda Y, Marubashi S, Nagano H, Umeshita K, Dono K, Matsubara K, Matsuura N and Monden M (2008) Molecular mapping of human hepatocellular carcinoma provides deeper biological insight from genomic data. European Journal of Cancer in press
Kittan G, Kumar KB, Guruvayoorappan C and Kuttan R (2007) Antitumor, anti-invasion, and antimetastaic effects of curcumin. Advances in Experimental Medicine and Biology 595 173-184
Kizaki T, Izawa T, Sakurai T, Haga S, Taniguchi N, Tajiri H, Watanabe K, Day NK, Toba K and Ohno H (2008) beta(2)-Adrenergic receptor regulates Toll-like receptor-4-induced nuclear factor-kB activation through beta-arrestin 2. Immunology in press
Klaas CA, Wagner G, Laufer S, Sosa S, Della Loggia R, Bomme U, Pahl HL and Merfort I (2002) Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers. Planta Med 68 385-391
Klaffenbach D, Rascher W, Rollinghoff M, Dotsch J, Meissner U and Schnare M (2005) Regulation and signal transduction of Toll-like receptors in human chorioncarcinoma cell lines. Am J Reprod Immunol 53 77-84
Klahr S (1999) Mechanisms of progression of chronic renal damage. Journal of Nephrology 12 Suppl 2 S53-62
Klahr S and Morrissey JJ (1998) The role of growth factors, cytokines, and vasoactive compounds in obstructive nephropathy. Seminars in Nephrology 18 622-632
Klahr S and Morrissey J (2003) Progression of chronic renal disease. American Journal of Kidney Disease 41 S3-S7
Klaitman V and Almog Y (2003) Corticosteroids in sepsis: a new concept for an old drug. Israel Medical Association Journal 5 51-55
Klamon LD and Thorley-Lawson DA (1995) Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kB element. Journal of Virology 69 871-881
Klatt A, Zhang Z, Kalantari P, Hankey PA, Gilmour DS and Henerson AJ (2008) The receptor tyrosine kinase RON represses HIV-1 transcription by targeting RNA polymerase II processivity. Journal of Immunology 180 1670-1677
Klaunig JE and Kamendulis LM (2004) The role of oxidative stress in carcinogenesis. Annual Revew of Pharmacology and Toxicology 44 239-267
Klebanoff SJ, Watts DH, Mehlin C and Headley CM (1999) Lactobacilli and vaginal host defense: activation of the human immunodeficiency virus type 1 long terminal repeat, cytokine production, and NF-kB. Journal of Infectious Disease 179 653-660
Klebl FH, Bregenzer N, Rogler G, Straub RH, Scholmerich J and Andus T (2003) Treatment of pouchitis with dehydroepiandrosterone (DHEA) – a case report. Z Gastroenterol 41 1087-1090
Kleemann R, Gervois PP, Verschuren L, Staels B, Princen HM and Kooistra T (2003) Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkB ~C/EBP-beta complex formation. Blood 101 545-551
Kleemann R, Verschuren L, De Rooij BJ, Lindeman J, De Maat MM, Szalai AJ, Princen HM and Kooistra T (2004) Evidence for anti-inflammatory activity of statins and PPAR{alpha}-activators in human C-reactive protein transgenic mice in vivo and in cultured human hepatocytes in vitro. Blood 103 4188-4194
Kleemann R, Vershuren L, van Erk MJ, Nikolsky Y, Cnubben NH, Verheij ER, Smilde AK, Hendriks HF, Zadelaar S, SMith GJ, Kaznacheev V, Nikolskaya T, Melnikov A, Hurt-Camejo E, van der Greef J, van Ommen B and Kooistra T (2007) Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis. Genome Biology 8 R200
Klefstrom J, Arighi E, Littlewood T, Jaattela M, Saksela E, Evan GI and Alitalo K (1997) Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kB activation. EMBO Journal 16 7382-7392
Klei LR and Barchowsky A (2008) Positive signaling interactions between arsenic and ethanol for angiogenic gene induction in human microvascular endothelial cells. Toxicological Sciences in press
Klein BS, Liptay S, Schmid RM and Hameister H (1999) Assignment of Nfkbib to murine chromosome bands 7A3-B3 by in situ hybridization. Cytogenet Cell Genet 85 308-309
Klein C, Wustefeld T, Heinrich PC, Streetz KL, Manns MP and Trautwein C (2003) ME3738 protects from concanavalin A-induced liver failure via an IL-6-dependent mechanism. European Journal of Immunology 33 2251-2261
Klein D, Barbe-Tuana F, Pugliese A, Ichii H, Garza D, Gonzalez M, Molano RD, Ricordi C and Pastori RL (2005) A functional CD40 receptor is expressed in pancreatic beta cells. Diabetologia 48 268-276
Klein D, Timoneri F, Ichii H, Ricordi C and Pastori RL (2008) CD40 activation in human pancreatic islets and ductal cells. Diabetologia in press
Klein EA, Yang C, Kazanietz MG and Assoian RK (2007) NFkB-independent signaling to the cyclin D1 gene by Rac. Cell Cycle in press
Klein S, De Fougerolles AR, Blaikie P, Khan L, Pepe A, Green CD, Koteliansky V and Giancotti FG (2002) alpha5beta1 Integrin activates an NF-kB-dependent program of gene expression important for angiogenesis and inflammation. Molecular and Cellular Biology 22 5912-5922
Klein SL, Cernetich A, Hilmer S, Hoffman EP, Scott AL and Glass GE (2004) Differential expression of immunoregulatory genes in male and female Norway rats following infection with Seoul virus. Journal of Medical Virology 74 180-190
Kleinert H, Pautz A, Linker K and Schwarz PM (2004) Regulation of the expression of inducible nitric oxide synthase. European Journal of Pharmacology 500 255-266
Kleinert H, Schwarz PM and Forstermann U (2003) Regulation of the expression of inducible nitric oxide synthase. Biol Chem 384 1343-1364
Kleinert H, Wallerath T, Fritz G, Ihrig-Biedert I, Rodriguez-Pascual F, Geller DA and Forstermann U (1998) Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-kB-signaling pathways. British Journal of Pharmacology 125 193-201
Kleinman MT, Araujo JA, Nel A, Sioutas C, Campbell A< Cong PQ, Li H and Bondy SC (2008) Inhaled ultrafine particulate matter affects CNS inflammatory processes and may act via MAP kinase signaling pathways. Toxicology Letters in press
Kleino A, Myllymaki H, Kallio J, Vanha-Aho LM, Oksanen K, Ulvila J, Hultmark D, Valanne S and Ramet M (2008) Pirk is a negative regulator of the Drosophila imd pathway. Journal of Immunology 180 5413-5422
Klement JF, Rice NR, Car BD, Abbondanzo SJ, Powers GD, Bhatt H, Chen C-H, Rosen CA and Stewart CL (1996) IkBa deficiency results in a sustained NF-kB response and severe widespread dermatitis in mice. Molecular and Cellular Biology 16 2341-2349
Klemm S, Gutermuth J, Hultner L, Sparwasser T, Behrendt H, Peschel C, Mak TW, Jakob T and Ruland J (2006) The Bcl10-Malt1 complex segregates Fc{varepsilon}RI-mediated nuclear factor kB activation and cytokine production from mast cell degranulation.
Journal of Experimental Medicine 203 337-347
Klemm S and Ruland J (2006) Inflammatory signal transduction from the FcepsilonRI to NF-kB. Immunobiology 211 815-820
Klemm S, Zimmermann S, Peschel C, Mak TW and Ruland J (2006) Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kB activation and cytokine production. Proceedings of the National Academy of Sciences USA in press
Kletsas D, Pratsinis H, Mariatos G, Zacharatos P and Gorgoulis VG (2004) The proinflammatory phenotype of senescent cells: the p53-mediated ICAM-1 expression. Annals of the New York Academy of Sciences 1019 330-332
Kline M, Donovan K, Wellik L, Lust C, Jin W, Moon-Tasson L, Xiong Y, WItzig TE, Kumar S, Rajkumar SV and Lust JA (2006) Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression. Leukemia Research in press
Klingenberg R, Autschbach F, Gleissner C, Giese T, Wambsganss N, Sommer N, Richter G, Katus HA and Dengler TJ (2005) Endothelial inducible costimulator ligand expression is increased during human cardiac allograft rejection and regulates endothelial cell-dependent allo-activation of CD8(+) T cells in vitro. European Journal of Immunology 35 1712-1721
Klingmuller Y, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Gotschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preiss R, McaNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weizsacker F and Hengstler JG (2006) Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways. Systems Biology (Stevenage) 153 433-447
Klinke 2nd DJ, Ustyugova IV, Brundage KM and Barnett JB (2008) Modulating temporal control of NF-kB activation: implications for therapeutic and assay selection. Biophysical Journal in press
Klinkenberg M, Van Huffel S, Heyninck K and Beyaert R (2001) Functional redundancy of the zinc fingers of A20 for inhibition of NF- kappaB activation and protein-protein interactions. FEBS Letters 498 93-97
Klooster AR and Bernier SM (2005) Tumor necrosis factor alpha and epidermal growth factor act additively to inhibit matrix gene expression by chondrocyte. Arthritis Research and Therapy 7 R127-138
Klotz L, Schmidt M, Giese T, Sastre M, Knolle P, Klockgether T and Heneka MT (2005) Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. Journal of Immunology 175 4948-4955
Klug CA, Gerety SJ, Shah PC, Chen Y-Y, Rice NR, Rosenberg N and Singh H (1994) The v-abl tyrosine kinase negatively regulates NF-kB/Rel factors and blocks k gene transcription in pre-B lymphocytes. Genes & Development 8 678-687
Kluiver J, Kok K, Pfeil I, de Jong D, Blokzijl T, Harms G, van der Vlies P, Diepstra A, Atayar C, Poppema S, Kuppers R and van den Berg A (2007) Global correlation of genome and transcriptome changes in classical Hodgkin lymphoma. Hematology andOncology 25 21-29
Kluiver J, van den Berg A, de Jong D, Blokzijl T, Harms G, Bouwman E, Jacobs S, Poppema S and Kroesen BJ (2007) Regulation of pri-microRNA BIC transcription and processing in Burkitt lymphoma. Oncogene 26 3769-3776
Klysik J, Theroux SJ, Sedivy JM, Joffit JS and Bokelheide K (2007) Signaling crossroads: The function of Raf kinase inhibitory protein in cancer, the central nervous system and reproduction. Cellular Signaling in press
Knonickova E, Melkusova P, Harmatha J, Vokac K, Farghali H and Zidek Z (2008) Inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPase thapsigargin stimulates production of nitric oxide and secretion of interferon-gamma. European Journal of Pharmacology in press
Knecht H, Berger C, Rothenberger S, Odermatt BF and Brousset P (2001) The role of Epstein-Barr virus in neoplastic transformation. Oncology 60 289-302
Knecht H, McQuain C, Berger C, Rothenberger S, Martin J, Esslinger C, Drexler HG, Cai YC and Quesenberry PJ (1999) Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin’s disease. Oncogene 18 7161-7167
Knecht H, McQuain C, Martin J, Rothenberger S, Drexler HG, Berger C, Bachmann E, Kittler ELW, Odermatt BF and Quesenberry PJ (1996) Expression of the LMP1 oncoprotein in the EBV negative Hodgkin’s disease cell line L-428 is associated with Reed-Sternberg cell morphology. Oncogene 13 947-953
Knipp BS, Ailawadi G, Ford JW, Peterson DA, Eagleton MJ, Roelofs KJ, Hannawa KK, Deogracias MP, Ji B, Logsdon C, Graziano KD, Simeone DM, Thompson RW, Henke PK, Stanley JC and Upchurch GR (2004) Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kB and activator protein-1 activity(1). Journal of Surgical Research 116 70-80
Kniss DA, Rovin B, Fertel RH and Zimmerman PD (2001) Blockade NF-kB activation prohibits TNF-alpha-induced cyclooxygenase-2 gene expression in ED27 trophoblast-like cells. Placenta 22 80-89
Knittweis J (1998) An ataxia telangiectasia model: inefficient cell differentiation and possible reversal by serine protease inhibitors, tumor necrosis factor inhibitors, dexamethasone, and glutathione enhancers. Medical Hypotheses 51 53-57
Knobloch TJ, Madhavan S, Nam J, Agarwal Jr S and Agarwal S (2008) Regulation of chondrocytic gene expression by biomechanical signals. Critical Reviews of Eukaryotic Gene Expression 18 139-150
Knop J and Martin MU (1999) Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity. FEBS Letters 448 81-85
Knop J, Wesche H, Lang D and Martin MU (1998) Effects of overexpression of IL-1 receptor-associated kinase on NFkB activation, IL-2 production and stress-activated protein kinases in the murine T cell ine EL4. European Journal of Immunology 28 3100-3109
Knorre A, Wagner M, Schaefer HE, Colledge WH and Pahl HL (2002) DeltaF508-CFTR causes constitutive NF-B activation through an ER-overload response in cystic fibrosis lungs. Biology and Chemistry 383 271-282
Knosel T, Emde A, Schluns K, Chen Y, Jurchott K, Krause M, Dietel M and Petersen I (2005) Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer. Neoplasia 7 741-747
Knowles H and Thanasou N (2008) Hypoxia-inducible factor is expressed in giant cell tumour of bone and mediates paracrine effects of hypoxia on monocyte-osteoclast differentiation via induction of VEGF. Journal of Pathology in press
Knuefermann P, Chen P, Misra A, Shi SP, Abdellatif M and Sivasubramanian N (2002) Myotrophin/V-1, a protein upregulated in the failing human heart and in postnatal cerebellum converts NF-kB p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. Journal of Biological Chemistry 277 23888-23897
Knuefermann P, Chen P, Misra A, Shi SP, Abdellatif M and Sivasubramanian N (2002) Myotrophin/V-1, a protein up-regulated in the failing human heart and in postnatal cerebellum, converts NFkB p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. Journal of Biological Chemistry 277 23888-23897
Knuefermann P, Sakata Y, Baker JS, Huang CH, Sekiguchi K, Hardarson HS, Takeuchi O, Akira S and Vallejo JG (2004) Toll-like receptor 2 mediates Staphylococcus aureus-induced myocardial dysfunction and cytokine production in the heart. Circulation 110 3693-3698
Knuefermann P, Schwederski M, Velten M, Krings P, Ehrentraut H, Rudiger M, Boehm O, Fink K, Dreiner U Grohe C, Hoeft A, Baumgarten G, Koch A, Zacharowski K and Meyer R (2008) Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of Toll-like receptor 9. Cardiovascular Research in press
Ko GJ, Kang YS, Han SY, Lee MH, SOng HK, Han KH, Kim HK, Han JY and Cha DR (2008) Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrology, Dialysis and Transplantation in press
Ko HC, Kuo YH, Wei BL and Chiou WF (2005) Title?> Planta Med 71 514-519
Ko HM, Jung HH, Seo KH, Kang YR, Kim HA, Park SJ, Lee HK and Im SY (2006) Platelet-activating factor-induced NF-kB activation enhances VEGF expression through a decrease in p53 activity. FEBS Letters 580 3006-3012
Ko HM, Kang JH, Choi JH, Park SJ, Bai S and Im SY (2005) Platelet-activating factor induces matrix metalloproteinase-9 expression through Ca(2+)- or PI3K-dependent signaling pathway in a human vascular endothelial cell line. FEBS Letters 579 6451-6458
Ko HM, Kang JH, Jung B, Kim HA, Park SJ, Kim KJ, Kang YR, Lee HK and Im SY (2007) Critical role for matrix metalloproteinase-9 in platelet-activating factor-induced experimental tumor metastasis. International Journal of Cancer 120 1277-1283
Ko HM, Park YM, Jung B, Kim HA, Choi JH, Park SJ, Lee HK and Im SY (2005) Involvement of matrix metalloproteinase-9 in platelet-activating factor-induced angiogenesis. FEBS Letters 579 2369-2375
Ko HM, Seo KH, Han SJ, Ahn KY, Choi IH, Koh GY, Lee HK, Ra MS and Im SY (2002) Nuclear factor kB dependency of platelet-activating factor-induced angiogenesis. Cancer Research 62 1809-1814
Ko HW, Park KY, Kim H, Han PL, Kim YU, Gwag BJ and Choi EJ (1998) Ca2+-mediated activation of c-Jun N-terminal kinase and nuclear factor kB by NMDA in cortical cell cultures. Journal of Neurochemistry 71 1390-1395
Ko J, Kim IS, Jang SW, Lee YH, Shin SY, Min do S and Na DS (2002) Leukotactin-1/CCL15-induced chemotaxis signaling through CCR1 in HOS cells. FEBS Letters 515 159-164
Ko JH, Lee SJ and Lim KT (2005) 36kDa Glycoprotein isolated from Rhus verniciflua Stokes fruit has a protective activity to glucose/glucose oxidase-induced apoptosis in NIH/3T3 cells. Toxicology In Vitro 19 353-363
Ko JH, Lee SJ and Lim KT (2005) 116 kDa glycoprotein isolated from Ulmus davidiana Nakai (UDN) inhibits glucose/glucose oxidase (G/GO)-induced apoptosis in BNL CL.2 cells. Journal of Ethnopharmacology 100 339-346
Ko JS, Yang HR, Chang JY and Seo JK (2007) Lactobacillus plantarum inhibits epithelial barrier dysfunction and interleukin-8 secretion induced by tumor necrosis factor-alpha. World Journal of Gastroenterology 13 1962-1965
Ko S, Shi L, Kim S, Song CS and Chatterjee B (2008) Interplay of NF-kB and B-myb in the negative regulation of androgen receptor expression by TNFa. Molecular Endocrinology 22 273-286
Ko YG, Park H, Kim T, Lee JW, Park SG, Seol W, Kim JE, Lee WH, Kim SH, Park JE and Kim S (2001) A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes. Journal of Biological Chemistry 276 23028-23033
Koay MA, Christman JW, Segal BH, Venkatakrishnan A, Blackwell TR, Holland SM and Blackwell TS (2001) Impaired pulmonary NF-kappaB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice. Infection and Immunity 69 5991-5996
Koay MA, Christman JW, Wudel LJ, Allos T, Cheng DS, Chapman WC and Blackwell TS (2002) Modulation of endotoxin-induced NF-kB activation in lung and liver through TNF type 1 and IL-1 receptors. American Journal of Physiology: Lung Cell and Molecular Physiology 283 L1247-L1254
Kobashi C, Urakaze M, Kishida M, Kibayashi E, Kobayashi H, Kihara S, Funahashi T, Takata M, Temaru R, Sato A, Yamazaki K, Nakamura N and Kobayashi M ((2005) Adiponectin inhibits endothelial synthesis of interleukin-8. Circulation Research 97 1245-1252
Kobayashi A, Matsui M, Kubo T and Natori S (1993) Purification and characterization of a 59-kilodalton protein that specifically binds to NF-kB-binding motifs of the defense protein genes of Sarcophaga peregrina (the flesh fly). Molecular and Cellular Biology 13 4049-4056
Kobayashi H (2006) Endogenous anti-inflammatory substances, inter-alpha-inhibitor and bikunin. Biological Chemistry 387 1545-1549
Kobayashi H, Espinosa III R, Thirman MJ, Davis EM, Diaz MO, Le Beau MM, Rowley JD (1993) Variability of 11q23 rearrangements in hematopoietic cell lines identified with fluorescence in situ hybridization. Blood 81 3027-3033
Kobayashi H, Yagyu T, Kondo T, Kurita N, Inagaki K, Haruta S, Kawaguchi R, Kitanaka T, Sakamoto Y, Yamada Y, Kanayama N and Terao T (2005) Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kB activation and subsequently suppressed ovarian cancer dissemination. Cancer Research 65 10464-10471
Kobayashi I, Yamamoto S, Nishi N, Tsuji K, Imayoshi M, Inada S, Ichiamaru T and Hamasaki Y (2004) Regulatory mechanisms of Th2 cytokine-induced eotaxin-3 production in bronchial epithelial cells: possible role of interleukin 4 receptor and nuclear factor-kB. Annals of Allergy, Asthma and Immunology 93 390-397
Kobayashi K, Hernandez LD, Galan JE, Janeway Jr CA, Medzhitov R and Flavell RA (2002) IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 110 191-202
Kobayashi K, Kambe F, Kurokouchi K, Sakai T, Ishiguro N, Iwata H, Koga K and Seo H (1999) Effects of vector-averaged gravity on NF-kB activation in human osteoblast-like cells. Environmental Medicine 43 25-27
Kobayashi K, Matsumoto S, Morishima T, Kawabe T and Okamoto T (2000) Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Research 60 3978-3984
Kobayashi N, Kadono Y, Naito A, Matsumoto K, Yamamoto T, Tanaka S and Inoue J (2001) Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO Journal 20 1271-1280
Kobayashi N, Mita SI, Yoshida K, Honda T, Kobayashi T, Hara K, Nakano S, Tsubokou Y and Matsuoka H (2003) Celiprolol activates eNOS through the PI3K-Akt pathway and inhibits VCAM-1 via NF-kB induced by oxidative stress. Hypertension 42 1004-1013
Kobayashi N, Yoshida K, Mita SI, Honda T, Hara K, Nakano S, Tsubokou Y and Matsuoka H (2004) Betaxolol stimulates eNOS production associated with LOX-1 and VEGF in Dahl salt-sensitive rats. Journal of Hypertension 22 1397-1402
Kobayashi O, Miwa H, Watanabe S, Tsujii M, Dubois RN and Sato N (2001) Cyclooxygenase-2 downregulates inducible nitric oxide synthase in rat intestinal epithelial cells. American Journal of Physiology: Gastrointestinal Liver Physiology 281 G688-G696
Kobayashi S, Nagino M, Komatsu S, Naruse K, Nimura Y, Nakanishi M and Sokabe M (2003) Stretch-induced IL-6 secretion from endothelial cells requires NF-kB activation. Biochemical and Biophysical Research Communications 308 306-312
Kobayashi S, Okamoto H, Iwamoto T, Toyama Y, Tomatsu T, Yamanaka H and Momohara S (2008) A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis. Rheumatology (Oxford) in press
Kobayashi T, Okamoto N, Sawasaki T and Endo Y (2004) Detection of protein-DNA interactions in crude cellular extracts by fluorescence correlation spectroscopy. Analytical Biochemistry 332 58-66
Kobayashi Y and Takahashi N (2008) Genomic approaches to bone and joint diseases. Mutations of RANK, OPG and RANKL genes found in humans [Article in Japanese]. Clinical Calcium 18 202-209
Kobayashi Y and Udagawas N (2007) Mechanisms of alveolar bone remodeling {Japanese].Clinical Calcium 17 209-216
Kobayashi Y, Ueki S, Maheumuti B, Chiba T, Oyamda H, Saito N, Kanda A, Kayaba H and Chihara J (2005) Physiological levels of 15-deoxy-delta12,14-prostaglandin J2 prime eotaxin-induced chemotaxis on human eosinophils through peroxisome proliferator-activated receptor-gamma ligation. Journal of Immunology 175 5744-5750
Kobayashi Y, Ueyama S, Arai Y, Yoshida Y, Kaneda T, Sato T, Shin K, Kumegawa M and Hakeda Y (2004) The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage. Journal of Bone and Mineral Metabolism 22 318-328
Kobielak A and Fuchs E (2006) Links between alpha-catenin, NF-kB, and squamous cell carcinoma in skin. Proceedings of the National Academy of Sciences USA 103 2322-2327
Kobayashi-Sakamoto M, Hirose K, Isogai E and Chiba I (2004) NF-kB-dependent induction of osteoprotegerin by Porphyromonas gingivalis in endothelial cells. Biochemical and Biophysical Research Communications 315 107-112
Kobayashi-Sakamoto M, Isogai E, Hirose K and Chiba I (2008) Role of alpha(v) integrin in osteoprotegerin-induced endothelial cell migration and proliferation. Microvascular Research in press
Kobori M, Nakayama N, Fukushima K, Ohnishi-Kameyama M, Ono H, Fukushima T, AKimoto Y, Masumoto S, Yukizaki C, Hoshi Y, Deguchi T and Yoshida M (2008) Bitter gourd suppresses lipopolysaccharide-induced inflammatory responses. Journal of Agricultural Food Chemsitry in press
Kobori M, Yang Z, Gong D, Heissmeyer V, Zhu H, Jung YK, Gakidis MA, Rao A, Sekine T, Ikegami F, Yuan C and Yuan J (2003) Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibiting the IKK complex. Cell Death & Differentiation 11 123-130
Kobori M, Yoshida M, Ohnishi-Kameyama M and Shinmoto H (2007) Ergosterol peroxide from an edible mushroom suppresses inflammatory responses in RAW264.7 macrophages and growth of HT29 colon adenocarcinoma cells. British Journal of Pharmacology 150 209-219
Kobuchi H, Roy S, Sen CK, Nguyen HG and Packer L (1999) Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathway. American Journal of Physiology 277 C403-C411
Kocabas C, Katsenelson N, Kanswal S, Kennedy MN, Cui X, Blake MS, Segal DM and Akkoyunlu M (2007) Neisseria meningitidis type C capsular polysaccharide inhibits lipooligosaccharide-induced cell activation by binding to CD14. CellularMicrobiology in press
Kocer SS, Djuric PM, Bugallo MF, Simon SR and Matic M (2008) Transcriptional profiling of putative human epithelial stem cells. BMC Genomics 9 359
Koch A, Giembycz M, Ito K, Lim S, Jazrawi E, Barnes PJ, Adcock I, Erdmann E and Chung KF (2003) MAP-kinase modulation of NF-kB-induced GM-CSF release from human alveolar macrophages. American Journal of Respiratroy Cell and Molecular Biology 30 342-349
Koch A, Giembycz M, Stirling RG, Lim S, Adcock I, Wassermann K, Erdmann E and Chung KF (2004) Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages. European Respiratory Journal 23 805-812
Koch E, Klaas CA, Rungeler P, Castro V, Mora G, Vichnewski W and Merfort I (2001) Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kB. Biochemical Pharmacology 62 795-801
Kochel T and Rice NR (1992) v-rel- and c-rel-protein complexes bind to the NF-kB site in vitro. Oncogene 7 567-572
Kochel T, Mushinski JF and Rice NR (1991) The v-rel and c-rel proteins exist in high molecular weight complexes in avian and murine cells. Oncogene 6 615-626
Kochi Y, Yamada R, Suzuki A, Harley JB, Shirasawa S, Sawada T, Bae SC, Tokuhiro S, Chang X, Sekine A, Takahashi A, Tsunoda T, Ohnishi Y, Kaufman KM, Kang CP, Kang C, Otsubo S, Yumura W, Mimori A, Koike T, Nakamura Y, Sasazuki T and Yamamoto K (2005) A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nature Genetics 37 478-485
Kochlatyi S, Gibbons N and Mattana J (2002) Extracellular matrix oxidation modulates survival, NF-kB translocation, and MAPK activity in mesangial cells. Experimental and Molecular Pathology 73 191-197
Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Ramet M and Ezekowitz RA (2005) Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 123 335-346
Koczan D, Drynda S, Hecker M, Drynda A, Guthke R, Kekow J and Thiesen HJ (2008) Molecular discrimination of responders and non-responders to anti-TNF-a therapy in rheumatoid arthritis by etanercept. Arthritis Research and Therapy 10 R50
Kodach LL, Bos CL, Duran N, Peppelenbosch MP, Ferreira CV and Hardwick JC (2006) Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells.
Carcinogenesis 27 508-516
Kodaki T, Izui K and Katsuki H (1983) Cell volume change of Escherichia coli under stringent control. Apparent increase of K+ in rel- cells. Biochimica et Biophysica Acta 761 223-230
Kode A, Yang SR and Rahman I (2006) Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells.Respiratory Research 7 132
Koduru PRK, Lichtman SM, Smilari TF, Sun T, Goh JC, Karp L, Hall W, Hashimoto S, Chiorazzi N and Broome JD (1993) Serial pheotypic, cytogenetic and molecular genetic studies in Richter’s syndrome: demonstration of lymphoma development from the chronic lymphocytic leukaemia cells. British Journal of Haematology 85 613-616
Koedel U, Angele B, Rupprecht T, Wagner H, Roggenkamp A, Pfister HW and Kirschning CJ (2003) Toll-like receptor 2 participates in mediation of immune response in experimental pneumococcal meningitis. Journal of Immunology 170 438-444
Koedood Zhao M, Wang Y, Murphy K, Yi J, Beckerle MCand Gilmore TD (1999) LIM domain-containing protein Trip6 can act as a co-activator for the v-Rel transcription factor. Gene Expression 8 207-217
Koenigsknecht-Talboo J and Landreth GE (2005) Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines. Journal of Neuroscience 25 8240-8249
Koerber K, Sass G, Kiemer AK, Vollmar AM and Tiegs G (2002) In vivo regulation of inducible no synthase in immune-mediated liver injury in mice. Hepatology 36 1061-1069
Kofod-Olsen E, Ross-Hansen K, Mikkelsen JG and Hollsberg P (2008) Human herpesvirus 6B U19 protein is a PML-regulated transcriptional activator that localizes to nuclear foci in a PML-independent manner. Journal of General Virology 89 106-116
Koga T, Torigoshi T, Motokawa S, Miyashita T, Maeda Y, Nakamura M, Komori A, Aiba Y, Uemura T, Yatsuhashi H, Ishibashi H, Eguchi K, Migita K (2008) Serum amyloid A-induced IL-6 production by rheumatoid synoviocytes. FEBS Letters in press
Kogel D, Peters M, Konig HG, Hashemi SM, Bui NT, Arolt V, Rothermundt M and Prehn JH (2004) S100B potently activates p65/c-Rel transcriptional complexes in hippocampal neurons: Clinical implications for the role of S100B in excitotoxic brain injury. Neuroscience 127 913-920
Kogoshi H, Tohda S, Fu L, Koyama T and Nara N (2005) Effect of Notch ligands on in vitro sensitivity to chemo-therapeutic drugs in leukemia and lymphoma cells.Oncology Reports 14 723-726
Koh DC, Armugam A and Jeyaseelan K (2004) Sputa nerve growth factor forms a preferable substitute to mouse 7S-beta nerve growth factor. Biochemical Journal 383 149-158
Koh HS, Lee C, Lee KS, Ham CS, Seong RH, Kim SS and Jeon SH (2008) CD7 expression and galectin-1-induced apoptosis of immature thymocytes are directly regulated by NF-kB upon T-cell activation. Biochemical and Biophysical Research Communications in press
Koh JM, Lee YS, Kim YS, Kim DJ, Kim HH, Park JY, Lee KU and Kim GS (2006) Homocysteine enhances bone resorption by stimulation of osteoclast formation and activity through increased intracellular ROS generation. Journal of Bone and Mineral Research 21 1003-1011
Koh SH, Chang DI, Kim HT, Kim J, Kim MH, Kim KS, Bae I, Kim H, Kim DW and Kim SH (2005) Effect of 3-aminobenzamide, PARP inhibitor, on matrix metalloproteinase-9 level in plasma and brain of ischemic stroke model. Toxicology 214 131-139
Koh Y, Kang JL, Park W, Pack IS, Lee HS, Kim MJ and Lim CM (2001) Inhaled nitric oxide down-regulates intrapulmonary nitric oxide production in lipopolysaccharide-induced acute lung injury. Critical Care Medicine 29 1169-1174
Kohashi M, Ishimaru N, Arakaki R and Hayashi Y (2008) Effective treatment with oral administration of rebamipide in a mouse model of Sjögren’s syndrome. Arthritis and Rhematism 58 389-400
Kohlberg R (1991) Basic and clinical HIV-1 researchers target NF-kB protein. Journal of NIH Research 3 28-29
Kohlberg R (1997) Tangled pathways: new roles for NF-kB, TNF-a in apoptosis. Journal of NIH Research 9 29-32
Kohler HB, Knop J, Martin M, de Bruin A, Huchzermeyer B, Lehmann H, Kietzmann M, Meier B and Nolte I (1999) Involvement of reactive oxygen species in TNF-alpha mediated activation of the transcription factor NF-kB in canine dermal fibroblasts. Veterinary Immunology and Immunopathology 71 125-142
Kohlhaas SL, Craxton A, Sun X-M, Pinkoski MJ and Cohen GM 92007) Receptor-mediated apoptosis-inducing ligand (TRAIL)-induced apoptosis. Journal of Biological Chemistry 282 12831-12841
Koide M, Maeda H, Roccisana JL, Kawanabe N and Reddy SV (2003) CytokineRegulation and the signaling mechanism of osteoclast inhibitory peptide-1 (OIP-1/hSca) to inhibit osteoclast formation. Journal of Bone and Mineral Research 18 458-465
Koide N, Sugiyama T, Mori I, Mu MM, Yoshida T and Yokochi T (2003) C(2)-ceramide inhibits LPS-induced nitric oxide production in RAW 264.7 macrophage cells through down-regulating the activation of Akt. Journal of Endotoxin Research 9 85-90
Koike T, Shimada T, Fujii Y, Chen G, Tabei K, Namatame T, Yamagata M, Tajima A, Yoneda M, Terano A and Hiraishi H (2007) Up-regulation of TFF1 (pS2) expression by TNF-a in gastric epithelial cells.
Journal of Gastroenterology and Hepatology 22 936-942
Koike T, Yamagishi H, Hatanaka Y, Fukushima A, Chan JW, Xia Y, Fields M, Chandler P and Iwashima M (2003) A novel ERK dependent signaling process that regulates IL-2 expression in a late phase of T cell activation. Journal of Biological Chemistry 278 15685-15692
Koishi R, Yoshimura C, Kohama T and Serizawa N (2002) Leustroducsin B Activates Nuclear Factor-kappaB via the Acidic Sphingomyelinase Pathway in Human Bone Marrow-Derived Stromal Cell Line KM-102. Journal of Interferon and Cytokine Research 22 343-350
Koizumi N, Hatano E, Nitta T, Tada M, Harada N, Taura K, Ikai I and Shimahara Y (2005) Blocking of PI3K/Akt pathway enhances apoptosis induced by SN-38, an active form of CPT-11, in human hepatoma cells. International Journal of Oncology 26 1301-1306
Kojima H, Aizawa Y, Yanai Y, Nagaoka K, Takeuchi M, Ohta T, Ikegami H, Ikeda M and Kurimoto M (1999) An essential role for NF-kB in IL-18-induced IFN-gamma expression in KG-1 cells. Journal of Immunology 162 5063-5069
Kojima M, Morisaki T, Izuhara K, Uchiyama A, Matsunari Y, Katano M and Tanaka M (2000) Lipopolysaccharide increase cyclo-oxygenase-2 expression in a colon carcinoma cell line through nuclear factor-kB activation. Oncogene 19 1225-1231
Kojima T, Morikawa Y, Copeland NG, Gilbert DJ, Jenkins NA, Senba E and Kitamura T (2000) TROY, a newly identified member of the tumor necrosis factor receptor superfamily exhibits a homology with Edar and is expressed in embryonic skin and hair follicles. Journal of Biological Chemistry 275 20742-20747
Kokkinakis DM (2006) Methionine-stress: A pleiotropic approach in enhancing the efficacy of chemotherapy. Cancer Letters 233 195-207
Kokkinakis DM, Liu X, Chada S, Ahmed MM, Shareef MM, Singha UK, Yang S and Luo J (2004) Modulation of gene expression in human central nervous system tumors under methionine deprivation-induced stress. Cancer Research 64 7513-7525
Kokkinakis DM, Rushing EJ, Shareef MM, Ahmed MM, Yang S, Singha UK and Luo J (2004) Physiology and gene expression characteristics of carcinogen-initiated and tumor-transformed glial progenitor cells derived from the CNS of methylnitrosourea (MNU)-treated Sprague-Dawley rats. Journal of Neuropathology and Experimental Neurology 63 1182-1199
Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA and Harris HE (2005) RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scandinavian Journal of Immunology 61 1-9
Kokura S, Rhoads CA, Wolf RE, Yoshikawa T, Granger DN and Aw T (2001) NF-kB signaling in posthypoxic endothelial cells: relevance to E-selectin expression and neutrophil adhesion. Journal of Vascular Research 38 47-58
Kokura S, Wolf RE, Yoshikawa T, Granger DN and Aw TY (1999) Molecular mechanisms of neutrophil-endothelial cell adhesion induced by redox imbalance. Circulation Research 84 516-524
Kokura S, Wolf RE, Yoshikawa T, Ichikawa H, Granger DN and Aw TY (2000) Endothelial cells exposed to anoxia/reoxygenation are hyperadhesive to T-lymphocytes: kinetics and molecular mechanisms. Microcirculation 7 13-23
Kokura S, Yoshida N, Imamoto E, Ueda M, Ishikawa T, Uchiyama K, Kuchide M, Naito Y, Okanoue T and Yoshikawa T (2004) Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines. Cancer Letters 211 79-87
Kokura S, Yoshida N, Ishikawa T, Higashihara H, Sakamoto N, Takagi T, Uchiyama K, Naito Y, Mazda O, Okanoue T and Yoshikawa T (2005) Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon26 adenocarcinoma in mice. Cancer Letters 218 171-179
Kokura S, Yoshida N, Sakamoto N, Ishikawa T, Takagi T, Higashihara H, Nakabe N, Handa O, Naito Y and Yoshikawa T (2005) The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kB. Cancer Letters 228 223-233
Kokura S, Yoshida N, Ueda M, Imamoto E, Ishikawa T, Takagi T, Naito Y, Okanoue T and Yoshikawa T (2003) Hyperthermia enhances tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer Letters 20 89-96
Kol A, Bourcier T, Lichtman AH and Libby P (1999) Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages. Journal of Clinical Investigation 103 571-577
Kol A, Lichtman AH, Finberg RW, Libby P and Kurt-Jones EA (2000) Cutting edge: heat shock protein (HSP) 60 activates the innate immune response: CD14 is an essential receptor for HSP60 activation of mononuclear cells. Journal of Immunology 164 13-17
Kolenko V, Bloom T, Rayman P, Bukowski R, Hsi E and Finke J (1999) Inhibition of NF-kB activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of caspase-1 and -3. Journal of Immunology 163 590-598
Kolesnick R and Golde DW (1994) The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77 325-328
Kolev K, Skopal J, Simon L, Csonka E, Machovich R and Nagy Z (2003) Matrix metalloproteinase-9 expression in post-hypoxic human brain capillary endothelial cells: H(2)O(2) as a trigger and NF-kB as a signal transducer. Thrombosis and Haemostosis 90 528-537
Kollet JI and Petro TM (2006) IRF-1 and NF-kB p50/cRel bind to distinct regions of the proximal murine IL-12 p35 promoter during costimulation with IFN-gamma and LPS. Molecular Immunology 43 623-633
Kollisch G, Kalali BN, Voelcker V, Wallich R, Behrendt H, Ring J, Bauer S, Jakob T, Mempel M and Ollert M (2005) Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. Immunology 113 531-541
Kolonics A, Apati A, Janossy J, Brozik A, Gati R, Schaefer A and Magocsi M (2001) Activation of Raf/ERK1/2 MAP kinase pathway is involved in GM-CSF-induced proliferation and survival but not in erythropoietin-induced differentiation of TF-1 cells. Cell Signaling 13 743-754
Kolyada AY, Fedtsov A and Madias NE (2001) 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors upregulate inducible NO synthase expression and activity in vascular smooth muscle cells. Hypertension 38 1024-1029
Komander D and Barford D (2007) Structure of the A20 OTU domain and mechanistic insights into deubiquitination. Biochemical Journal 409 77-85
Komander D, Lord CJ, Scheel H, Swift S, Hofmann K, Ashworth A and Barford D (2008) The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. Molecular Cell 29 451-464
Komarova EA, Krivokrysenko V, Wang K, Neznanov N, Chernov MV, Komarov PG, Brennan ML, Golovkina TV, Rokhlin O, Kuprash DV, Nedospasov SA, Hazen SR, Feinstein E and Gudkov AV (2005) p53 is a suppressor of inflammatory response in mice. FASEB Journal 19 130-132
Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K and Gudkov AV (2003) p53 inhibitor PFTalpha can suppress heat shock and glucocorticoid signaling pathways. Journal of Biological Chemistry 278 15465-15468
Komatsu H, Hoshino A, Funayama M, Kawahara K and Obata F (2003) Oxidative modulation of the glutathione-redox couple enhances lipopolysaccharide-induced interleukin 12 P40 production by a mouse macrophage cell line, J774A.1. Free Radical Research 37 293-299
Komatsu T, Takeuchi K, Yokoo J and Gotoh B (2004) C and V proteins of Sendai virus target signaling pathways leading to IRF-3 activation for the negative regulation of interferon-beta production. Virology 325 137-148
Komatsu W, Ishihara K, Murata M, Saito H and Shinohara K (2003) Docosahexaenoic acid suppresses nitric oxide production and inducible nitric oxide synthase expression in interferon-gamma plus lipopolysaccharide-stimulated murine macrophages by inhibiting the oxidative stress. Free Radical Biology and Medicine 34 1006-1016
Komine K, Kuroishi T, Ozawa A, Komine Y, Minami T, Shimauchi H and Sugawara S (2007) Cleaved inflammatory lactoferrin peptides in parotid saliva of periodontitis patients. Molecular Immunology 44 1498-1508
Komine M, Rao LS, Kaneko T, Tomic-Canic M, Tamaki K, Freedberg IM and Blumenberg M (2000) Inflammatory versus proliferative processes in epidermis. Tumor necrosis factor alpha induces K6b keratin synthesis through a transcriptional complex containing NFkB and C/EBPb. Journal of Biological Chemistry 275 32077-32088
Komine M, Watabe Y, Shimaoka S, Sato F, Kake K, Nishina H, Ohtsuki M, Nakagawa H and Tamaki K (1999) The action of a novel vitamin D3 analogue, OCT, on immunomodulatory function of keratinocytes and lymphocytes. Archives of Dermatological Research 291 500-506
Komninou D, Ayonote A, Richie JP Jr and Rigas B (2003) Insulin resistance and its contribution to colon carcinogenesis. Experimental Biology and Medicine 228 396-405
Komiya T, Miura K, Tsukamoto J, Okamura M, Tamada S, Asai T, Tashiro K, Kuwabara N, Iwao H and Yoshikawa J (2004) Possible involvement of nuclear factor-kB inhibition in the renal protective effect of oral adsorbent AST-120 in a rat model of chronic renal failure. International Journal of Molecular Medicine 13 133-138
Komjati K, Besson VC and Szabo C (2005) Poly (ADP-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma. Curr Drug Targets CNS Neurol Disord 4 179-194
Komura E, Tonetti C, Penard-Lacronique V, Chagraoui H, Lacout C, Lecouedic JP, Rameau P, Debili N, Vainchenker W and Giraudier S (2005) Role for the nuclear factor kB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression.Cancer Research 65 3281-3289
Komori J, Marusawa H, Machimoto T, Endo Y, Kinoshita K, Kou T, Haga H, Ikai I, Uemoto S and Chiba T (2008) Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma. Hepatology 47 888-896
Komuro H, Olee T, Kuhn K, Quach J, Brinson DC, Shikhman A, Valbracht J, Creighton-Achermann L and Lotz M (2001) The osteoprotegerin/receptor activator of nuclear factor kB/receptor activator of nuclear factor kB ligand system in cartilage. Arthritis & Rheumatism 44 2768-2776
Komura H, Uchiba M, Mizuochi Y, Arai M, Harada N, Katsuya H and Okajima K (2007) Antithrombin inhibits lipopolysaccharide-induced tumour necrosis factor-alpha production by monocytes in vitro through inhibition of Egr-1 expression. Journal of Thrombois and Haemostosis in press
Kon A, Vindevoghel L, Kouba DJ, Fujimura Y, Uitto J and Mauviel A (1999) Cooperation between SMAD and NF-kB in growth factor regulated type VII collagen gene expression. Oncogene 18 1837-1844
Konda R, Sugimura J, Sohma F, Katagiri T, Nakamura Y and Fujioka T (2008) Over expression of hypoxia-inducible protein 2, hypoxia-inducible factor-1a and nuclear factor kB is putatively involved in acquired renal cyst formation and subsequent tumor transformation in patients with end stage renal failure. Journal of Urology in press
Kondo A, Mogi M, Koshihara Y and Togari A (2001) Signal transduction system for interleukin-6 and interleukin-11 synthesis stimulated by epinephrine in human osteoblasts and human osteogenic sarcoma cells. Biochemical Pharmacology 61 319-326
Kondo T, Higashiyama Y, Goto S, Iida T, Cho S, Iwanaga M, Mori K, Tani M and Urata Y (1999) Regulation of gamma-glutamylcysteine synthetase expression in response to oxidative stress. Free Radical Research 31 325-334
Kondo T, Kitazawa R, Yamaguchi and Kitazaz S (2007) Dexamethasone promotes osteoclastogenesis by inhibiting osteoprotegerin through multiple levels. Journal ofCellular Biochemistry in press
Kondo Y, Fukuda K, Adachi T, Nishida T (2008) Inhibiton by a selective IkB kinase-2 inhibtor of interleukin-1-induced collagen degradation by corneal fibroblast in three-dimensional culture. Invest Ophthalmol Vis Sci 49 4850-4857
Kondoh M, Nagashima F, Suzuki I, Harada M, Fujii M, Asakawa Y and Watanabe Y (2005) Induction of apoptosis by new ent-kaurene-type diterpenoids isolated from the New Zealand liverwort Jungermannia species. Planta Medica 71 1005-1009
Konduri SD, Yanamandra N, Dinh DH, Olivero WC, Gujrati M, Foster DC, Kisiel W and Rao JS (2003) Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells. International Journal of Oncology 22 1277-1283
Kong AN, Yu R, Lei W, Mandlekar S, Tan TH and Ucker DS (1998) Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis: the role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis. Restor Neurol Neurosci 12 63-70
Kong D, Li Y, Wang Z, Banerjee S and Sarkar FH (2007) Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-kB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Research 67 3310-3319
Kong D, Park EJ, Stephen AG, Calvani M, Cardellina JH, Monks A, Fisher RJ, Shoemaker RH and Melillo G (2005) Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity. Cancer Research 65 9047-9055
Kong D, Wang Z, Sarkar SH, Li Y, Banerjee S, Salignan A, Kim HR, Cher ML and Sarkar FH (2008) PDGF-D over-expression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells. Stem Cells in press
Kong LN, Zuo PP, Mu L, Liu YY and Yang N (2005) Gene expression profile of amyloid beta protein-injected mouse model for Alzheimer disease. Acta Pharmacologica Sinica26 666-672
Kong X, Wang X, Xu W, Beherea S, Hellermann G, Kumar A, Lockey RF, Mohapatra S adn Hohapatra SS (2008) Natriuretic peptide receptor a as a novel anticancer target. Cancer Research 68 249-256
Kong XN, Yan HX, Chen L, Dong LW, Tang W, Liu Q, Yu LX, Huang DD, Liu SQ, Liu H, Wu MC and Wang HY (2007) LPS-induced down-regulation of signal regulatory protein alpha contributes to innate immune activation in macrophages. Journal of ExperimentalMedicine 204 2719-2731
Konig HG, Kogel D, Rami A and Prehn JH (2005) TGF-beta1 activates two distinct type I receptors in neurons: implications for neuronal NF-kB signaling. Journal of Cell Biology 168 1077-1086
Konishi H, Nakatsuka M, Chekir C, Noguchi S, Kamada Y, Sasaki A and Hiramatsu Y (2004) Advanced glycation end products induce secretion of chemokines and apoptosis in human first trimester trophoblasts. Human Reproduction 19 2156-2162
Konish M, Nishitani C, Mitsuzawa H, Shimizu T, Sano H, Harimaya A, Fujii N, Himi T and Kuroki T (2006) Alloiococcus otitidis is a ligand for collectins and Toll-like receptor 2, and its phagocytosis is enhanced by collectins. European Journal ofImmunology 36 1527-1536
Konishi T, Sasaki S, Watanabe T, Kitayama J and Nagawa H (2006) Overexpression of hRFI inhibits 5-fluorouracil-induced apoptosis in colorectal cancer cells via activation of NF-kB and upregulation of BCL-2 and BCL-XL. Oncogene 25 3160-3169
Kono H, Rusyn I, Bradford BU, Connor HD, Mason RP and Thurman RG (2000) Allopurinol prevents early alcohol-induced liver injury in rats. Journal of Pharmacology and Experimental Therapeutics 293 296-303
Kono H, Rusyn I, Uesugi T, Yamashina S, Connor HD, Dikalova A, Mason RP and Thurman RG (2001) Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat. American Journal of Physiology: Gastrointestinal and Liver Physiology 280 G1005-G1012
Kono H, Wheeler MD, Rusyn I, Lin M, Seabra V, Rivera CA, Bradford BU, Forman DT and Thurman RG (2000) Gender differences in early alcohol-induced liver injury: role of CD14, NF-kB, and TNF-a. American Journal of Physiology: Gastrointestinal and Liver Physiology 278 G652-G661
Konsman JP, Vigues S, Mackerlova L, Bristow A and Blomqvist A (2004) Rat brain vascular distribution of interleukin-1 type-1 receptor immunoreactivity: Relationship to patterns of inducible cyclooxygenase expression by peripheral inflammatory stimuli. Journal of Comparative Neurology 472 113-129
Konson A, Mahajna JA, Danon A, Rimon G and Agbaria R (2006) The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene. Cancer Gene Therapy 13 1093-1104
Konstantinopoulos PA, Vandoros GP, Karamouzis MV, Gkermpesi M, Sotiropoulou-Bonikou G and Papvassiliou AG (2007) EGF-R is expressed and AP-1 and NF-kB are activated in stromal myofibroblasts surrounding colon adenocarcinomas paralleling expression of COX-2 and VEGF. Cellualr Oncology 29 477-482
Konstantinopoulos PA, Vandoros GP, Sotiropoulou-Bonikou G, Kominea A and Papvassiliou AG (2007) NF-kB/PPARg and/or AP-1/PPARgamma ‘on/off’ switches and induction of CBP in colon adenocarcinomas: correlation with COX-2 expression.International Journal of Colorectal Disease 22 57-68
Köntgen F, Grumont RJ, Strasser A, Metcalf D, Li R, Tarlinton D and Gerondakis S (1995) Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity and interleukin-2 expression. Genes & Development 9 1965-1977
Kontny E, Kurowska M, Szczepanska K and Maslinski W (2000) Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes. Journal of Leukocyte Biology 67 249-258
Kontou M, Adelfalk C, Hirsch-Kauffmann M and Schweiger M (2003) Suboptimal action of NF-kB in Fanconi anemia cells results from low levels of thioredoxin. Biol Chem 384 1501-1507
Kontou M, Will RD, Adelfalk C, Wittig T, Poustka A, Hirsch-Kauffmann M and Schweiger M (2004) Thioredoxin, a regulator of gene expression. Oncogene 23 2146-2152
Konturek PC, Brzozowski T, Walter B, Burnat G, Hess T, Hahn EG and Konturek SJ (2006) Ghrelin-induced gastroprotection against ischemia-reperfusion injury involves an activation of sensory afferent nerves and hyperemia mediated by nitric oxide.European Journal of Pharmacology 536 171-181
Konturek PC, Kania J, Konturek JW, Nikiforuk A, Hahn EG and Konturek SJ (2003) H. pylori infection, atrophic gastritis, cytokines, gastrin, COX-2, PPARgamma and impaired apoptosis in gastric carcinogenesis. Med Sci Monit 9 SR53-SR66
Konturek PC, Nikiforuk A, Kania J, Raithel M, Hahn EG and Muhldorfer S (2004) Activation of NFkB represents the central event in the neoplastic progression associated with Barrett’s esophagus: a possible link to the inflammation and overexpression of COX-2, PPARg and growth factors. Dig Dis Sci 49 1075-1083
Koo HJ, Song YS, Kim HJ, Lee YH, Hong SM, Kim SJ, Kim BC, Jin C, Lim CJ and Park EH (2004) Antiinflammatory effects of genipin, an active principle of gardenia. European Journal of Pharmacology 495 201-208
Koo HN, Hong SH, Seo HG, Yoo TS, Lee KN, Kim NS, Kim CH and Kim HM (2003) Inulin stimulates NO synthesis via activation of PKC-a and protein tyrosine kinase, resulting in the activation of NF-kB by IFN-g-primed RAW 264.7 cells. Journal of Nutritional Biochemistry 14 598-605
Koo HN, Jeong HJ, Park JH, Moon G, Chae HJ, Kim HR, Kim CH, Seo SB, An NH and Kim HM (2001) Kunbi-Boshin-Hangam-Tang stimulates nitic oxide production through activation of nuclear factor-kB. Immunopharmacology and Immunotoxicology 23 175-186
Koo JW and Duman RS (2008) IL-1 is an essential mediator of the antineurogenic and anhedonic effects of stress. Proceedings of the National Academy of Sciences USA in press
Koo SW, Casper KA, Otto KB, Gira AK and Swerlick RA (2003) Iron chelators inhibit vcam-1 expression in human dermal microvascular endothelial cells. Journal of Investigative Dermatology 120 871-879
Koo TH, Lee JH, Park YJ, Hong YS, Kim HS, Kim KW and Lee JJ (2001) A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kB by targeting IkB phosphorylation. Planta Medica 67 103-107
Kooistra T, Verschuren L, van der Weij J, Koenig W, Toet K, Princen HM and Kleemann R (2006) Fenofibrate reduces atherogenesis in ApoE*3Leiden mice: evidence for multiple antiatherogenic effects besides llowering plasma cholesterol.Arteriosclerosis, Thrombosis & Vascular Biology 26 2322-2330
Koon HW, Zhao D, Zhan Y, Simeonidis S, Moyer MP and Pothoulakis C (2005) Substance P-stimulated interleukin-8 expression in human colonic epithelial cells involves PKCdelta activation. Journal of Pharmacology and Experimental Therapeutics 314 1393-1400
Koong A, Chen E, Mivechi N, Denko N, Stambrook P and Giaccia A (1994) Hypoxic activation of NF-kB is mediated by a Ras and Ras signaling pathway and does not involve MAP kinase (ERK1 or ERK2). Cancer Research 54 5273-5279
Koong AC, Chen EY and Giacca AJ (1994) Hypoxia causes the activation of nuclear factor kB through the phosphorylation of IkBa on tyrosine residues. Cancer Research 54 1425-1430
Kopecky-Bromberg SA, Martinex-Sobrido L, Frieman M, Baric RA and Palese P (2006) SARA coronavirus proteins ORF 3B, ORF 6, and nucleocapsid function as interferon antagonists Journal of Virology in press
Kopp E and Ghosh S (1994) Inhibition of NF-kB by sodium salicylate and aspirin. Science 265 956-959
Kopp E and Ghosh S (1995) NF-kB and Rel proteins in innate immunity. Advances in Immunology 58 1-27
Kopp E, Medzhitov R, Carothers J, Xiao C, Douglas I, Janeway CA and Ghosh S (1999) ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes & Development 13 2059-2071
Kopp EB and Medzhitov R (1999) The Toll-receptor family and control of innate immunity. Current Opinions in Immunology 11 13-18
Koppel H, Yard BA, Christ M, Wehling M and Van Der Woude FJ (2003) Modulation of angiotensin II-mediated signalling by heparan sulphate glycosaminoglycans. Nephrol Dial Transplant 18 2240-2247
Korashy HM and El-Kadi AO (2007) The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper. Free Radical Biology and Medicine in press
Korashy HM and El-Kadi AO (2008) Reply to Dvorak and Pavek, Letter to the Editor, regarding “The role of redox-sensitive transcription factors NF-kB and AP-1 in the modulation of Cyp1a1 gene by mercury, lead, and copper” Free Radical Biology and Medicine in press
Korbelik M, Sun J and Cecic I (2005) Photodynamic therapy-induced cell surface expression and release of heat shock proteins: relevance for tumor response. Cancer Research 65 1018-1026
Korber B, Okayama A, Donnelly R, Tachibana N and Essex M (1991) Polymerase chain reaction analysis of defective human T-cell leukemia virus type I proviral genomes in leukemic cells of patients with adult T-cell leukemia. Journal of Virology 65 5471-5476
Korchynskyi O, Dechering KJ, Sijbers AM, Olijve W and ten Dijke P (2003) Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation. Journal of Bone & Mineral Research 18 1177-1185
Korcok J, Raimundo LN, Du X, Sims SM and Dixon SJ (2005) P2Y6 nucleotide receptors activate NF-kB and increase survival of osteoclasts. Journal of Biological Chemistry 280 16909-16915
Korcok J, Raimundo LN, Ke HZ, Sims SM and Dixon SJ (2004) Extracellular nucleotides act through P2X7 receptors to activate NF-kB in osteoclasts. Journal of Bone and Mineral Research 19 642-651
Kordes U, Krappmann D, Heissmeyer V, Ludwig WD and Scheidereit C (2000) Transcription factor NF-kB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia 14 399-402
Kordula T, Bugno M, Rydel RE and Travis J (2000) Mechanism of interleukin-1- and tumor necrosis factor alpha -dependent regulation of the alpha 1-antichymotrypsin gene in human astrocytes. Journal of Neuroscience 20 7510-7516
Korhonen R, Korpela R and Moilanen E (2002) Signalling mechanisms involved in the induction of inducible nitric oxide synthase by Lactobacillus rhamnosus GG, endotoxin, and lipoteichoic acid. Inflammation 26 207-214
Korhonen R, Kosonen O, Korpela R and Moilanen E (2004) The expression of COX2 protein induced by Lactobacillus rhamnosus GG, endotoxin and lipoteichoic acid in T84 epithelial cells. Lett Appl Microbiol 39 19-24
Korkmaz A, Topal T and Oter S (2007) Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell Biology and Toxicology in press
Korkolopoulou P,Levidou G, Saetta AA, El-Habr E, Eftichiadis C, Demenagas P, Thymara I, Xiromeritis K, Boviatsis E, Thomas-Tsagli E, Panayotidis I and Patsouris E (2008) Expression of nuclear factor-kB in human astrocytomas: relation to pIkBa, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival. Human Pathology in press
Korn SH, WOuters EFM, Vos N and Janssen-Heininger YMW (2001) Cytokine-induced activation of nuclear factor-kB is inhibited by hydrogen peroxide through oxidative inactivation of IkB kinase. Journal of Biological Chemistry 276 35693-35700
Korner M, Rattner A, Mauxion F, Sen R and Citri Y (1993) A brain-specific transcription activator. Neuron 3 563-572
Körner M, Tarantino N and Debré P (1991) Constitutive activation of NF-kB in human thymocytes. Biochemical and Biophysical Research Communications 181 80-86
Korobko EV, Saschenko LP, Prockhorchouk EB, Korobko IV, Gnuchev NV and Kiselev SL (1999) Resistance to tumor necrosis factor induced apoptosis in vitro correlates with high metastatic capacity of cells in vivo. Immunology Letters 67 71-76
Korobowicz A (2006) Biology of tumor necrosis factor type alpha (TNF-a) [Article in Polish]. Polski Merkuriusz Lekarski 21 358-361
Korus M, Mahon GM, Cheng L and Whitehead IP (2002) p38 MAPK-mediated activation of NF-kB by the RhoGEF domain of Bcr. Oncogene 21 4601-4612
Kos O, Castro V, Murillo R, Poveda L and Merfort I (2005) Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa.Phytochemistry 67 62-69
Kos O, Lindenmeyer MT, Tubaro A, Sosa S and Merfort I (2005) Sequiterpene lactones from Arnica montana inhibit NF-kB (tentative title). Planta Medica 71 1044-1052
Kosalec I and Pepeljnjak S (2004) Chemistry and biological effects of gliotoxin [Article in Croatian]. Arh Hig Rada Toksikol 55 313-320
Kosco KA< Cerignoli F, WIlliams S< Abraham RT andMustelin T (2007) SKAP55 modulates T cell antigen receptor-induced activation of the Ras-Erk-AP1 pathway by binding RasGRP1. Molecular Immunology in press
Koseki M, Hirano KI, Masuda D, Ikegami C, Tanaka M, Ota A, Sandoval JC, Nakagawa-Toyama Y, Sato SB, Kobayashi T, Shimada Y, Ohno-Iwashita Y, Matsuura F, Shimomura I and Yamashita S (2006) Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor alpha secretion in ABCa1-deficient macrophages.Journal of Lipid Research in press
Koseki T, Inohara N, Chen S, Carrio R, Merino J, Hottiger MO, Nabel GJ and Nunez G (1999) CIPER, a novel NF- kB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. Journal of Biological Chemistry 274 9955-9961
Koski GK, Lyakh LA, Cohen PA and Rice NR (2001) CD14+ monocytes as dendritic cell precursors: diverse maturation-inducing pathways lead to common activation of NF-kB/RelB. Critical Reviews in Immunology 21 179-189
Koskinen PK, Kallio EA, Tikkanen JM, Sihvola RK, Hayry PJ and Lemstrom KB (1999) Cytomegalovirus infection and cardiac allograft vasculopathy. Transpl Infect Dis 1 115-126
Kostadinova RM, Nawrocki AR, Frey FJ and Frey BM (2005) Tumor necrosis factor alpha and phorbol 12-myristate-13-acetate down-regulate human 11beta-hydroxysteroid dehydrogenase type 2 through p50/p50 NF-kB homodimers and Egr-1. FASEB Journal 19 650-652
Kota S, Sabbah A, Chang TH, Harnack R, Xiang Y, Meng X and Bose S (2008) Role of human beta defensin-2 during tumor necrosis factor-a/NF-kB mediated innate anti-viral response against human respiratory syncytial virus. Journal of Biological Chemistry in press
Kotake Y, Sang H, Miyajima T and Wallis GL (1998) Inhibition of NF-kB, iNOS mRNA COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN). Biochimica et Biophysica Acta 1448 77-84
Kotani J, Avallone NJ, Lin E, Goshima M, Gandhi K, Lowry SF and Calvano SE (2003) Fas-mediated neutrophil apoptosis and associated A1 protein expression during systemic inflammation are regulated independently of both tumor necrosis factor receptors. Shock 19 201-207
Kotarsky K, Antonsson L, Owman C and Olde B (2003) Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase. Analytical Biochemistry 316 208-215
Koteish A, Yang S, Lin H, Huang X and Diehl AM (2002) Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation. Journal of Biological Chemistry 277 13037-13044
Kothe H, Dalhoff K, Rupp J, Muller A, Kreuzer J, Maass M and Katus HA (2000) Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae. Circulation 101 1760-1763
Kothny-Wilkes G, Kulms D, Luger TA, Kubin M and Schwarz T (1999) Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand- and CD95-induced apoptosis but not from ultraviolet radiation-induced apoptosis. Journal of Biological Chemistry 274 28916-28921
Kothny-Wilkes G, Kulms D, Poppelmann B, Luger TA, Kubin M and Schwarz T (1998) Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand. Journal of Biological Chemistry 273 29247-29253
Kotla S, Peng T, Bumgarner RE and Gustin KE (2008) Attenuation of the type I interferon response in cells infected with human rhinovirus. Virology in press
Kotokorpi P, Gardmo C, Nystrom CS and Mode A (2004) Activation of the glucocorticoid receptor or liver X receptors interferes with growth hormone induced akr1b7 gene expression in rat hepatocytes. Endocrinology 145 5704-5713
Kouba DJ, Chung KY, Nishiyama T, Vindevoghel L, Kon A, Klement JF, Uitto J and Mauviel A (1999) Nuclear factor-kB mediates TNF-a inhibitory effect on alpha 2(I) collagen (COL1A2) gene transcription in human dermal fibroblasts. Journal of Immunology 162 4226-4234
Kouba DJ, Nakano H, Nishiyama T, Kang J, Uitto J and Mauviel A (2001) Tumor necrosis factor-alpha induces distinctive NF-kB signaling within human dermal fibroblasts. Journal of Biological Chemistry 276 6214-6224
Koubovec D, Berghe WV, Vermeulen L, Haegeman G and Hapgood JP (2004) Medroxyprogesterone acetate downregulates cytokine gene expression in mouse fibroblast cells. Molecular and Cellular Endocrinology 221 75-85
Kougias P, Wei D, Rice PJ, Ensley HE, Kalbfleisch J, Williams DL and Browder IW (2001) Normal human fibroblasts express pattern recognition receptors for fungal (1–>3)-beta-D-glucans. Infection and Immunity 69 3933-3938
Koul D, Takada Y, Shen R, Aggarwal BB and Yung WK (2006) PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kB signaling pathway in human glioma cells. Biochemical and Biophysical Research Communications 350 463-471
Koul D, Yao Y, Abbruzzese JL, Yung WK and Reddy SA (2001) Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkB activation without interfering with the IkB degradation pathway. Journal of Biological Chemistry 276 11402-11408
Koulich E, Nguyen T, Johnson K, Giardina C and D’Mello S (2001) NF-kB is involved in the survival of cerebellar granule neurons: association of IkBbeta phosphorylation with cell survival. Journal of Neurochemistry 76 1188-1198
Kourelis K, Papads T, Vandoros G, Goumas P and Sotiropoulou-Bonikou G (2007) Glottic versus supraglottic tumors: differential molecular profile. European Archives ofOtorhinolaryngology in press
Kourelis K, Sotiropoulou-Bonikou G, Vandoros G, Repanti M, Varakis I and Goumas P (2007) Coordinated upregulation of COX-2 and NF-kB is a steady feature of laryngeal carcinogenesis.
ORL Journal of Otorhinolaryngology and Related Specialties 69 181-189
Kouroedov A, Eto M, Joch H, Volpe M, Luscher TF and Cosentino F (2004) Selective inhibition of protein kinase C{beta}2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells. Circulation 110 91-96
Kourylko O, Fradette C, Arcand M and du Souich P (2006) Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and IL-6. Drug Metabolism and Disposition 34 27-35
Koutroubas G, Merika M and Thanos D (2007) Bypassing the requirements for epigenetic modifications in gene transcription by increasing enhancer strength. Molecular and Cellular Biology in press
Kovacich JC, Boyle EM, Jr., Morgan EN, Canty TG, Jr., Farr AL, Caps MT, Frank N, Pohlman TH and Verrier ED (1999) Inhibition of the transcriptional activator protein nuclear factor kB prevents hemodynamic instability associated with the whole-body inflammatory response syndrome. Journal of Thoracic and Cardiovascular Surgery 118 154-162
Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL and Finkel TH (2005) Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.
Journal of Immunology 175 7848-7854
Kovacs DA, Chakraborty-Sett S, Ramirez SH, Sniderhan LF, Williamson AL and Maggirwar SB (2004) Mechanism of NF-kB inactivation induced by survival signal withdrawal in cerebellar granule neurons. European Journal of Neuroscience 20 345-352
Kovalenko A, Chable-Bessia C, Cantarella G, Israel A, Wallach D and Courtois G (2003) The tumour suppressor CYLD negatively regulates NF-kB signalling by deqbiquitination. Nature 424 801-805
Kovalenko A and Wallach D (2006) If the prophet coes not come to the mountain: dynamics of signaling complexes in NF-kB activation. Molecular Cell 22 433-436
Kovalovich K, DeAngelis RA, Li W, Furth EE, Ciliberto G and Taub R (2000) Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice. Hepatology 31 149-159
Kovall RA and Hendrickson WA (2004) Crystal structure of the nuclear effector of Notch signaling, CSL, bound to DNA. EMBO Journal 23 3441-3451
Kovjazin R, Eldar T, Patya M, Vanichkin A, Lander HM and Novogrodsky A (2003) Ferrocene-induced lymphocyte activation and antitumor activity is mediated by redox-sensitive signaling. FASEB Journal 17 467-469
Kowalik TF, Wing B, Haskill JS, Azizkhan JC, Baldwin Jr AS and Huang E-S (1993) Multiple mechanisms are implicated in the regulation of NF-kB activity during human cytomegalovirus infection. Proceedings of the National Academy of Sciences USA 90 1107-1111
Kowalski MP and Pier GB (2004) Localization of cystic fibrosis transmembrane conductance regulator to lipid rafts of epithelial cells is required for Pseudomonas aeruginosa-induced cellular activation. Journal of Immunology 172 418-425
Kowluru RA (2005) Effect of advanced glycation end products on accelerated apoptosis of retinal capillary cells under in vitro conditions. Life Sciences 76 1051-1060
Kowluru RA, Chakrabarti S and Chen S (2005) Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kB) in the retina. Acta Diabetol 41 194-199
Kowluru RA and Kanwar M (2007) Effects of curcumin on retinal oxidative stress and inflammation in diabetes. Nutrition & Metabolism (London) 4 8
Kowluru RA, Koppolu P, Chakrabarti S and Chen S (2003) Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants. Free Radical Research 37 1169-1180
Kowluru RA, Kolluru A and Kanwar M (2006) Small molecular weight G-protein, H-Ras, and retinal endothelial cell apoptosis in diabetes. Molecular and CellularBiochemistry in press
Kowluru RA and Odenbach S (2004) Role of interleukin-1{beta} in the pathogenesis of diabetic retinopathy. British Journal of Opthalmology 88 1343-1347
Kowluru RA and Odenbach S (2004) Role of interleukin-1beta in the development of retinopathy in rats: effect of antioxidants. Investigative Ophthalmology and Visual Science 45 4161-4166
Koyama H, Suzuki Y, Ohwada Y and Saito Y (1976) Reticulendotheliosis group virus pathogenic to chicken isolated from material infected with turkey herpesvirus (HVT). Avian Diseases 20 429-434
Koyama S (2003) Differential expression of intracellular apoptotic signaling molecules in tumor and tumor-infiltrating lymphocytes during development of invasion and/or metastasis of gastric carcinoma. Dig Dis Sci 48 2290-2300
Koyama T, Sakamoto N, Tanabe Y, Nakagawa M, Itsui Y, Takeda T, Kakinuma S, Sekine Y, Maekawa S, Yanai Y, Kurimoto M and Watanabe M (2006) Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication.Hepatology Research 34 41-49
Koyanagi M, Hijikata M, Watashi K, Masui O and Shimotohno K (2005) Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor kB. Journal of Biological Chemistry 280 12430-12437
Koyano S, Saito Y, Nagano M, Maekawa K, Kikuchi Y, Murayama N, Fujino T, Ozawa S, Nakajima T, Matsumoto K, Saito H and Sawada JI (2003) Functional analysis of three genetic polymorphisms in the glucocorticoid receptor gene. Journal of Pharmacology and Experimental Therapeutics 307 110-116
Kozak W, Wrotek S and Kozak A (2005) Pyrogenicity of CpG-DNA in mice: Role of interleukin-6, cyclooxygenases, and nuclear-factor-kB. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 290 R871-R880
Koziak-Holbro M, Joyce C, Gluck A, Kinzel B, Muller M, Tshopp C, Mathison JC, Davis CN and Gram H (2007) IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and Toll-like receptor 7-mdiated signaling and gene expression. Journal of Biological Chemistry 282 13552-13560
Koziczak-Holbro M, Gluck A, Tschopp C, Mathison JC and Graim H (2008) IRAK-4 kinase activity-dependent and -independent regulation of lipopolysaccharide-inducible genes. European Journal of Immunology 38 788-796
Koziczak-Holbro M, Joyce C, Gluck A, Kinzel B, Muller M and Graam H (2007) Solving the IRAK-4 enigma: application of kinase-dead knock-in mice. Ernst Schering Foundation Symposium Proceedings 3 63-82
Kozlov IA, Kubareva EA and Shabarova ZA (1998) Use of synthetic oligonucleotides for inhibition of factor NF-kB. Molecular Biology (Moscow) 32 389-400
Kozlov S, Mounkes L, Cutler D, Sullivan T, Hernandez L, Levy N, Rottman J and Stewart CL (2005) Mutations in the mouse Lmna gene causing progeria, muscular dystrophy and cardiomyopathy. Novartis Foundation Symposium 264 246-258
Kozlov SV, Dobrovolskaia MA, Rice NR, Stewart CL and Vogel SN (2003) A novel cell-based system for the rapid quantitative evaluation of (anti)-inflammatory potential of test substances. Journal of Immunological Methods 281 51-63
Kraatz J, Clair L, Bellingham J, Wahlstrom K, Rodriguez JL and West MA (1998) Lipopolysaccharide pretreatment produces macrophage endotoxin tolerance via a serum-independent pathway. Journal of Trauma 45 684-691
Kracklauer MP and Schmidt C (2003) At the crossroads of SUMO and NF-κB. Molecular Cancer 2 39
Kraft C, Jenett-Siems K, Kohler I, Tofern-Reblin B, Siems K, Bienzle U and Eich E (2002) Antiplasmodial activity of sesquilignans and sesquineolignans from Bonamia spectabilis. Phytochemistry 60 167-173
Kraft M, Adler KB, Ingram JL, Crews AL, Atkinson TP, Cairns CB, Krause DC and Chu HW (2008) Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma. European Respiratory Journal 31 43-46
Kraft S and Bieber T (2001) Fc epsilon ri-mediated activation of transcription factors in antigen- presenting cells. International Archives of Allergy and Immunology 125 9-15
Kraft S, Katoh N, Novak N, Koch S and Bieber T (2001) Unexpected functions of FcepsilonRI on antigen-presenting cells. International Archives of Allergy and Immunology 124 35-37
Kraft S, Novak N, Katoh N, Bieber T and Rupec RA (2002) Aggregation of the high-affinity IgE receptor Fc(epsilon)RI on human monocytes and dendritic cells induces NF-kB activation. Journal of Investigative Dermatology 118 830-837
Krakauer T (2004) Molecular therapeutic targets in inflammation: cyclooxygenase and NF-kB. Current Pharmaceutical Design 3 317-324
Krakauer T and Buckley M (2008) The potency of anti-oxidants in attenuating superantigen-induced proinflammatory cytokines correlates with inactivation of NF-kB. Immunopharmacology and Immunotoxicology 30 163-179
Kralisch S, Klein J, Lossner U, Bluher M, Paschke R, Stumvoll M and Fasshauer M (2005) Proinflammatory adipocytokines induce TIMP-1 expression in 3T3-L1 adipocytes. FEBS Letters 579 6417-6422
Kralisch S, Sommer G, Stangl V, Kohler U, Kratzsch J, Stepan H, Faber R, Schubert A, Lossner U, Vietzke A, Bluher M, Stumvoll M and Fasshauer M (2007) Secretory products from human adipocytes impair endothelial function via nuclear factor kB.Atherosclerosis in press
Kralova J, Liss AS, Bargmann W and Bose Jr HR (1998) AP-1 factors play an important role in transformation induced by the v-rel oncogene. Molecular and Cellular Biology 18 2997-3009
Kralova J, Liss AS, Bargmann W, Pendleton C, Varadarajan J, Ulug E and Bose Jr HR Jr (2002) Differential regulation of the inhibitor of apoptosis ch-IAP1 by v-rel and the proto-oncogene c-rel. Journal of Virology 76 11960-11970
Kralova J, Schatzle JD, Bargmann W and Bose Jr HR (1994) Transformation of avian fibroblasts overexpressing the c-rel proto-oncogene and a variant of c-rel lacking 40 C-terminal amino acids. Journal of Virology 68 2073-2083
Kralova J, Schatzle JD, Liss AS, Bargmann W and Bose Jr HR (1996) Synergistic stimulation of avian IkBa by rel and fos/jun factors. Oncogene 12 2595-2604
Kramer AA, Salhab KF, Shafii AE, Norman J, Carey LC and Mendez C (1999) Induction of tolerance to hemorrhagic or endotoxic shock involves activation of NF-kB. Journal of Surgical Research 83 89-94
Kramer BW, Kaemmerer U, Kapp M, Herbst D, Marx A, Berg D, Groneck PA and Speer CP (2005) Decreased expression of angiogenic factors in placentas with chorioamnionitis after preterm birth. Pediatric Research 58 607-612
Kramer G, Steiner GE, Sokol P, Mallone R, Amann G and Marberger M (2003) Loss of CD38 correlates with simultaneous up-regulation of human leukocyte antigen-DR in benign prostatic glands, but not in fetal or androgen-ablated glands, and is strongly related to gland atrophy. BJU International 91 409-416
Kramer HF and Goodyear LJ (2007) Exercise, MAPK, and NF-kB signaling in skeletal muscle. Journal of Applied Physiology in press
Kramer OH, Baus D, Knauer SK, Stein S, Jager E, Stauber RH, Grez M, Pfitzner E and Heinzel T (2006) Acetylation of Stat1 modulates NF-kB activity. Genes andDevelopment 20 473-485
Krammer PH, Arnold R and Lavrik IN (2007) Life and death in peripheral T cells.Nature Reviews Immunology 7 532-542
Kranzhofer R, Browatzki M, Schmidt J and Kubler W (1999) Angiotensin II activates the proinflammatory transcription factor nuclear factor-kappaB in human monocytes. Biochemical and Biophysical Research Communications 257 826-828
Kranzhofer R, Schmidt J, Pfeiffer CA, Hagl S, Libby P and Kubler W (1999) Angiotensin induces inflammatory activation of human vascular smooth muscle cells. Arteriosclerosis, Thrombosis and Vascular Biology 19 1623-1629
Krappmann D, Emmerich F, Kordes U, Scharschmidt E, Dorken B and Scheidereit C (1999) Molecular mechanisms of constitutive NF-kB/Rel activation in Hodgkin/Reed Sternberg cells. Oncogene 18 943-953
Krappmann D, Patke A, Heissmeyer V and Scheidereit C (2001) B-cell receptor- and phorbol ester-induced NF-kB and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C’s. Molecular and Cellular Biology 21 6640-6650
Krappmann D nad Scheidereit C (2005) A pervasive role of ubiquitin conjugation in activation and termination of IkB kinase pathways. EMBO Reports 6 321-326
Krappmann D, Wegener E, Sunami Y, Esen M, Thiel A, Mordmuller B and Scheidereit C (2004) The IkB kinase complex and NF-kB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1. Molecular and Cellular Biology 24 6488-6500
Krappmann D, Wulczyn FG and Scheidereit C (1996) Different mechanisms control signal-induced degradation and basal turnover of the NF-kB inhibitor IkBa in vivo. EMBO Journal 15 6716-6726
Krasnow SW, Zhang LQ, Leung KY, Osborn L, Kunkel S and Nabel GJ (1991) Tumor necrosis factor-alpha, interleukin 1, and phorbol myristate acetate are independent activators of NF-kB which differnetially activates T cells. Cytokine 3 372-379
Kratsovnik E, Bromberg Y, Sperling O and Zoref-Shani E (2005) Oxidative stress activates transcription factor NF-kB-mediated protective signaling in primary rat neuronal cultures. Journal of Molecular Neuroscience 26 27-32
Krauer KG, Belzer DK, Liaskou D, Buck M, Cross S, Honjo T and Sculley T (1998) Regulation of interleukin-1b transcription by Epstein-Barr virus involves a number of latent proteins via their interaction with RBP. Virology 252 418-430
Kraus AC, Ferber I, Bachmann SO, Specht H, Wimmel A, Gross MW, Schlegel J, Suske G and Schuermann M (2002) In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways. Oncogene 21 8683-8695
Kraus DM and Bulla GA (1999) Defective NF-kB signaling in dedifferentiated hepatoma cells. Somatic Cell Molecular Genetics 25 275-286
Kraus J, Borner C, Giannini E and Hollt V (2003) The role of nuclear factor kB in tumor necrosis factor-regulated transcription of the human mu-opioid receptor gene. Molecular Pharmacology 64 876-884
Kraus M, Aimzhanov MB, Rajewsky N and Rajewsky K (2004) Survival of resting mature B lymphocytes depends on BCR signaling via the Iga/b heterodimer. Cell 117 787-800
Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Grauer DC, Lehmann M, Jeijler MM, Janda KD and Eulevitch RJ (2008) Modulation of gene expression via disruption of NF-kB signaling by a bacterial small molecule. Science in press
Kravchenko VV, Mathison JC, Schwamborn K, Mercurio F, Ulevitch RJ (2003) IKKi/IKKe plays a key role in integrating signals induced by pro-inflammatory stimuli. Journal of Biological Chemistry 278 26612-26619
Kray AE, Carter RS, Pennington KN, Gomez RJ, Sanders LE, LLanes JM, Khan WN, Ballard DW and Wadzinski BE (2005) Positive regulation of IkB kinase signaling by protein serine/threonine phosphatase 2A. Journal of Biological Cehmistry 280 35974-35982
Krebs M and Roden M (2004) Nutrient-induced insulin resistance in human skeletal muscle. Current Medicinal Chemistry 11 901-908
Krehan A, Ausuini H, Bocher O, Grein S, Wirkner U and Walter P (2000) Transcription factors Ets1, NFkB and Sp1 are major determinants of the promoter activity of the human protein dinase CK2a gene. Journal of Biological Chemistry 275 18327-18336
Kreja L, Liedert A, Schmidt C, Claes L and Ignatius A (2007) Influence of receptor activator of nuclear factor (NF)-kB ligand (RANKL), macrophage-colony stimulating factor (M-CSF) and fetal calf serum on human osteoclast formation and activity.Journal of Molecular Histology in press
Krejsek J, Kunes P, ANdrys C, Holicka M, Novosad J, Kudlova M and Kolackova M (2005) Innate immunity, receptors for exogenous and endogenous danger patterns in immunopathogenesis of atlherosclerosis–part 1: identification of danger signals by innate immunity [Article in Czech]. Cas Lek Cesk 144 785-789
Kretz-Remy C and Arrigo AP (2003) Modulation of the chymotrypsin-like activity of the 20S proteasome by intracellular redox status: effects of glutathione peroxidase-1 overexpression and antioxidant drugs. Biology and Chemistry 384 589-595
Kretz-Remy C and Tanguay RM (1999) SUMO/sentrin: protein modifiers regulating important cellular functions. Biochemistry and Cell Biology 77 299-309
Kretz-Remy C, Bates E and Arrigo AP (1998) Amino acid analogs activate NF-kB through redox-dependent IkB-a degradation by the proteasome without apparent IkB-a phosphorylation: Consequence on HIV-1 long terminal repeat activation. Journal of Biological Chemistry 273 3180-3191
Kretzmann NA, Fillmann H, Mauriz JL, Marroni CA, Marroni N, Gonzalez-Gallego J and Tunon MJ (2008) Effects of glutamine on proinflammatory gene expression and activation of nuclear factor kappa B and signal transducers and activators of transcription in TNBS-induced colitis. Inflammatory Bowel Disease in press
Kretzschmar M, Meisternernst M, Scheidereit C, Li G and Roeder RG (1992) Transcriptional regulation of the HIV-1 promoter by NF-kB in vitro. Genes & Development 6 761-774
Kreuz S, Siegmund D, Rumpf JJ, Samel D, Leverkus M, Janssen O, Hacker G, Dittrich-Breiholz O, Kracht M, Scheurich P and Wajant H (2004) NFkB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP. Journal of Cell Biology 166 369-380
Kreuz S, Siegmund D, Scheurich P and Wajant H (2001) NF-kB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Molecular and Cellular Biology 21 3964-3973
Kreydiyyeh SI and Al-Sadi R (2004) The signal transduction pathway that mediates the effect of interleukin-1 beta on the Na(+)-K(+)-ATPase in LLC-PK(1) cells. Pflugers Archives 448 231-238
Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annual Reviews of Immunology 20 709-760
Krieg AM (2000) The role of CpG motifs in innate immunity. Current Opinions in Immunology 12 35-43
Krieg AM, Guga P and Stec W (2003) P-chirality-dependent immune activation by phosphorothioate CpG oligodeoxynucleotides. Oligonucleotides 13 491-499
Kriehuber E, Bauer W, Charbonnier AS, Winter D, Amatschek S, Tamandl D, Schweifer N, Stingl G and Maurer D (2005) The balance between NF-kB and JNK/AP-1 activity controls dendritic cell life and death. Blood 106 175-183
Kriete A, Mayo KL, Yalamachili N, Beggs W, Bender P, Kari C and Rodeck U (2008) Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kB activity. Immune Ageing 5 in press
Krikos A, Laherty CD and Dixit VM (1992) Transcriptional activation of the tumor necrosis factor a-inducible zinc finger protein, A20, is mediated by kB elements. Journal of Biological Chemistry 267 17971-17976
Krillov A, Kistler B, Mostoslavsky R, Cedar H, Wirth T and Bergman Y (1996) A role for nuclear NF-kB in B-cell-specific demethylation of the Igk locus. Nature Genetics 13 435-441
Krippner-Heidenreich A, Tubing F, Bryde S, Willi S, Zimmermann G and Scheurich P (2002) Control of receptor-induced signaling complex (RISC) formation by the kinetics of ligand/receptor interaction. Journal of Biological Chemistry 277 44155-44163
Krisanaprakornkit S, Kimball JR and Dale BA (2002) Regulation of human beta-defensin-2 in gingival epithelial cells: the involvement of mitogen-activated protein kinase pathways, but not the NF-kB transcription factor family. Journal of Immunology 168 316-324
Krishna S, Jensen MH and Sneppen K (2006) Minimal model of spiky oscillations in NF-kB signaling. Proceedings of the National Academy of Sciences USA 103 10840-10845
Krishnamoorthy RR, Crawford MJ, Chaturvedi MM, Jain SK, Aggarwal BB, Al-Ubaidi MR and Agarwal N (1999) Photo-oxidative stress down-modulates the activity of nuclear factor-kB via involvement of caspase-1, leading to apoptosis of photoreceptor cells. Journal of Biological Chemistry 274 3734-3743
Krishnan VA, Schatzle JD, Hinojos CM and Bose Jr HR (1995) Structure and regulation of the gene encoding avian IkB-a. Gene 166 261-266
Krishnegowda G, Hajjar AM, Zhu J, Douglass EJ, Uematsu S, Akira S, Woods AS and Gowda DC (2005) Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols (GPIs) of Plasmodium falciparum: cell signaling receptors, GPI structural requirement, and regulation of GPI activity. Journal of Biological Chemistry 280 8606-8616
Kristof AS, Fielhaber J, Triantafillopoulos A, Menoto S and Joss J (2006) Phosphatidylinositol 3-kinase-dependent suppression of the human inducible nitric oxide synthase promoter is mediated by FKHRL1. Journal of Biological Chemistry 281 23958-23968
Kristof AS, Marks-Konczalik J and Moss J (2001) Mitogen-activated protein kinases mediate AP-1-dependent human inducible nitric oxide synthase promoter activation. Journal of Biological Chemistry 276 8445-8452
Kroczynska B and Carbone M (2006) Cross reactivity between many anti-human antibodies for their hamster homologs provide the tools to study the signal transduction pathway activated by asbestos and SV40 in the malignant mesothelioma model. Molecular Carcinogenesis 45 537-542
Kroemer JA and Webb BA (2006) Divergences in protein activity and cellular localization within the Campoletis sonorensis Ichnovirus vankyrin family. Journal ofVirology 80 12219-12228
Krohn K, Rozovsky I, Wals P, Teter B, Anderson CP and Finch CE (1999) Glial fibrillary acidic protein transcription responses to transforming growth factor-beta1 and interleukin-1beta are mediated by a nuclear factor-1-like site in the near-upstream promoter. Journal of Neurochemistry 72 1353-1361
Kroismayr R, Baranyi U, Stehlik C, Dorfleutner A, Binder BR and Lipp J (2004) HERC5, a HECT E3 ubiquitin ligase tightly regulated in LPS activated endothelial cells. Journal of Cell Science 117 4749-4756
Kroll M, Arenzana-Seisdedos F, Bachelerie F, Thomas D, Friguet B and Conconi M (1999) The secondary fungal metabolite gliotoxin targets proteolytic activities of the proteasome. Chemistry and Biology 6 689-698
Kroll M, Conconi M, Desterro MJP, Marin A, Thomas D, Friguet B, hay RT, Virelizier J-L, Arenzana-Seisdedos F and Rodriguez MS (1997) The carboxy-terminus of IkBa determines susceptibility to degradation by the catalytic core of the proteasome. Oncogene 15 1841-1850
Kroll M, Margottin F, Kohl A, Renard P, Durand H, Condcordet JP, Bachelerie F, Arenzana-Seisdedos F and Benarous R (1999) Inducible degradation of IkBa by the proteasome requires interaction with the F-box protein h-bTrCP. Journal of Biological Chemistry 274 7941-7945
Kroncke KD (2003) Nitrosative stress and transcription. Biol Chem 384 1365-1377
Krontiris TG (1995) Minisatellites and human disease. Science 269 1682-1683
Kroon ME, Koolwijk P, van der Vecht B and van Hinsbergh VW (2001) Hypoxia in combination with FGF-2 induces tube formation by human microvascular endothelial cells in a fibrin matrix: involvement of at least two signal transduction pathways. Journal of Cell Science 114 825-833
Krueger A. Bauma S, Krammer PH and Kirchhoff S (2001) FLICE-inhibitory ptoteins: regulators of death receptor-mediated apoptosis. Molecular and Cellular Biology 21 8247-8254
Kruez S, Siegmund D, Scheurich P, Wajant H (2001) NF-kB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Molecular and Cellular Biology 21 3964-3973
Krug LT, MOser JM, Dickerson SM and Speck SH (2007) Inhibition of NF-kB activation in vivo impairs establishment of gammaherpesvirus latency. PLoS Pathogenesis 3 e11
Krull M, Bockstaller P, Wuppermann FN, Klucken AC, Muhling J, Schmeck B, Seybold J, Walter C, Maass M, Rosseau S, Hegemann JH, Suttorp N and Hippenstiel S (2006) Mechanisms of Chlamydophila pneumoniae mediated GM-CSF release in human bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology 34 375-382
Krull M, Klucken AC, Wuppermann FN, Fuhrmann O, Magerl C, Seybold J, Hippenstiel S, Hegemann JH, Jantos CA and Suttorp N (1999) Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae. Journal of Immunology 162 4834-4841
Krunkosky TM, Fischer BM, Martin LD, Jones N, Akley NJ and Adler KB (2000) Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. American Journal of Respiratory Cell and Molecular Biology 22 685-692
Kruppa G, Thoma B, Machleidt T, Wiegmann K and Krönke M (1992) Inhibition of tumor necrosis factor (TNF) mediated NF-kB activation by selective blockade of the human 55-kd TNF receptor. Journal of Immunology 148 3152-3157
Krushel LA, Cunningham BA, Edelman GM and Crossin KL (1999) NF-kB activity is induced by neural cell adhesion molecule binding to neurons and astrocytes. Journal of Biological Chemistry 274 2432-2439
Kruyt FA (2008) TRAIL and cancer therapy. Cancer Letters in press
Krzesz R, Wagner AH, Cattaruzza M and Hecker M (1999) Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kB and signal transducer and activation of transcription-1. FEBS Letters 453 191-196
Ku CL, Dupuis-Girod S, Dittrich AM, Bustamante J, Santos OF, Schulze I, Bertrand Y, Couly G, Bodemer C, Bossuyt X, Picard C and Casanova JL (2005) NEMO mutations in 2 unrelated boys with severe infections and conical teeth. Pediatrics 115 e615-e619
Ku CL, Yang K, Bustamante J, Puel A, von Bernuth H, Santos OF, Lawrence T, Chang HH, Al-Mousa H, Picard C and Casanova JL (2005) Inherited disorders of human Toll-like receptor signaling: immunological implications. Immunology Reviews 203 10-20
Ku PT, You M, Bose HR (2000) Role and regulation of Rel/NF-kB activity in anti-immunoglobulin-induced apoptosis in WEHI-231 B lymphoma cells. Cellular Signaling 12 245-253
Kuai J, Nickbarg E, Wooters J, Qiu Y, Wang J and Lin LL (2003) Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis. Journal of Biological Chemistry 278 14363-14369
Kuang AA, Novak D, Kang S-M, Bruhn K and Lenardo MJ (1993) Interaction between NF-kB- and serum response factor-binding elements activates an interleukin-2 receptor a-chain enhancer specifically in T lymphocytes. Molecular and Cellular Biology 13 1536-1545
Kuang PP, Berk JL, Rishikof DC, Foster JA, Humphries DE, Ricupero DA and Goldstein RH (2002) NF-kB induced by IL-1beta inhibits elastin transcription and myofibroblast phenotype. Am J Physiol Cell Physiol 283 C58-C65
Kuang PP and Goldstein RH (2003) Regulation of elastin gene transcritpion by interleukin-1b-induced C/EBPb isoforms. American Journal of Physiology: Cell Physiology 285 L1147-L1152
Kuang PP and Goldstein RH (2005) Regulation of elastin gene transcription by proteasome dysfunction. American Journal of Physiology: Cell Physiology 289 C766-C773
Kuang X, Yan M, Liu N, Scofield VL, Qiang W, Cahill J, Lynn WS and Wong PK (2005) Control of Atm-/- thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone. Cancer Chemotherapy and Pharmacology 55 203-212
Kubo-Murai M, Hazeki K, Nigorikawa K, Omoto T, Inoue N and Hazeki O (2007) IRAK-4-dependent degradation of IRAK-1 is a negative feedback signal for TLR-mediated NF-kB activation. Journal of Biochemistry (Tokyo) in press
Kuboki S, Okaya T, Shuster R, Blanchard J, Denenberg A, Wong H and Lentsch AB (2007) Hepatocyte NF-kB activation is hepatoprotective during ischemia/reperfusion injury and is augmented by ischemic hypothermia. American Journal of Physiology:Gastrointestinal and Liver Physiology 292 G201-G207
Kuboki S, Schuster R, Blanchard J, Pritts TA, Wong H and Lentsch AB (2007) Role of heat shock protein 70 in hepatic ischemia/reperfusion injury in mice. AmericanJournal of Physiology: Gastrointestinal and Liver Physiology 292 G1141-G1149
Kubonishi I, Niiya K, Yamashita M, Yano S, Abe T, Ohtsuki Y, Miyoshi I (1986) Characterization of a new human lymphoma cell line (RC-K8) with t(11;14) chromosome abnormality. Cancer 58 1453-1460
Kubota K, Wakabayashi K and Matsuoka T (2003) Proteome analysis of secreted proteins during osteoclast differentiation using two different methods: Two-dimensional electrophoresis and isotope-coded affinity tags analysis with two-dimensional chromatography. Proteomics 3 616-626
Kubo E, Singh DP and Akagi Y (2005) Gene expression profiling of diabetic and galactosaemic cataractous rat lens by microarray analysis. Diabetologica 48 790-798
Kubo M, Morisaki T, Matsumoto K, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Nakamura K, Nakamura M and Katano M (2004) Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production. Cancer Immunology and Immunotherapy 54 468-476
Kubo-Murai M, Hazeki K, Nigorikawa K, Omoto T, Inoue N and Hazeki O (2007) IRAK-4-dependent degradation of IRAK-1 is a negative feedback signal for TLR-mediated NF-kB activation. Journal of Biochemistry in press
Kubo-Murai M, Hazeki K, Sukenobu N, Yoshikawa K, Nigorikawa K, Inoue K, Yamamoto T, Matsumoto M, Seya T, Inoue N and Hazeki O (2006) Protein kinase Cdelta binds TIRAP/Mal to participate in TLR signaling. Molecular Immunology 44 2257-2264
Kubota A, Hasegawa K, Suguro T and Koshihara Y (2004) Tumor necrosis factor-alpha promotes the expression of osteoprotegerin in rheumatoid synovial fibroblasts. Journal of Rheumatology 31 426-435
Kubota K and Gay NJ (1995) The dorsal protein enhances the biosynthesis and stability of the Drosophila IkB homologue cactus. Nucleic Acids Research 23 3111-3118
Kubota T, Kushikata T, Fang J and Krueger JM (2000) Nuclear factor-kB inhibitor peptide inhibits spontaneous and interleukin-1beta-induced sleep. American Journal of Physiology: Regulatory, Integrative and Compartative Physiology 279 R404-R413
Kubota T, Miyagishima M, Frye CS, Alber SM, Bounoutas GS, Kadokami T, Watkins SC, McTiernan CF and Feldman AM (2001) Overexpression of tumor necrosis factor-alpha activates both anti- and pro-apoptotic pathways in the myocardium. Journal of Molecular and Cellular Cardiology 33 1331-1344
Kubota Y, Sasaki S, Kubota H, Tatsura H and Kohri K (2001) A study on the mechanism of the spermatogenic damage after vasectomy in rats [Article in Japanese]. Nippon Hinyokika Gakkai Zasshi 92 13-22
Kucharczak J, Simmons MJ, Fan Y and Gelinas C (2003) To be, or not to be: NF-kB is the answer – role of Rel/NF-kB in the regulation of apoptosis. Apoptosis 22 8961-8982
Kudo S and Fukuda M (1995) Tissue-specific expression of human leukosialin (CD43) gene is regulated by DNA methylation. Abstract of the American Society for Cell Biology, Molecular Biology of the Cell 78a 456
Kudo T, Lu H, Wu JY, Graham DY, Casola A and Yamaoka Y (2005) Regulation of RANTES promoter activation in gastric epithelial cells infected with Helicobacter pylori. Infection and Immunity 73 7602-7612
Kudo T, Lu H, Wu JY, Ohno T, Wu MJ, Genta RM, Graham DY and Yamaoka T (2007) Pattern of transcription factor activation in Helicobacter pylori-infected Mongolian gerbils. Gastroenterology 132 1024-1038
Kudo Y, Guardavaccaro D, Santamaria PG, Koyama-Nasu R, Latres E, Bronson R, Yamasaki L and Pagano M (2004) Role of F-box protein {beta}Trcp1 in mammary gland development and tumorigenesis. Molecular and Cellular Biology 24 8184-8194
Kuefer R, Genze F, Zugmaier W, Hautmann RE, Rinnab L, Gschwend JE, Angelmeier M, Estrada A and Buechele B (2007) Antagonistic effects of sodium butyrate and N-(4-hydroxyphenyl)-retinamide on prostate cancer. Neoplasia 9 246-253
Kuenze P, Kiefer S, Koryakina A and Hamburger M (2008) Promotion of cell death or neurite outgrowth in PC-12 and N2a cells by the fungal alkaloid militarinone A depends on basal expression of p53. Apoptosis 13 364-376
Kufer TA, Banks DJ and Philpott DJ (2006) Innate immune sensing of microbes by Nod proteins. Annals of the New York Academy of Sciences 1072 19-27
Kufer TA, Kremmer E, Adam AC, Philpott DJ and Sansonetti PJ (2007) The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cellular Microbiology in press
Kufer TA, Kremmer E, Banks DJ and Philpott DJ (2006) Role for erbin in bacterial activation of nod2. Infection and Immunity 74 3115-3124
Kuhn DJ, Burns AC, Kazi A and Ping Dou Q (2004) Direct inhibition of the ubiquitin-proteasome pathway by ester bond-containing green tea polyphenols is associated with increased expression of sterol regulatory element-binding protein 2 and LDL receptor. Biochimica et Biophysica Acta 1682 1-10
Kuhn K and Lotz M (2001) Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes. Arthritis & Rheumatism 44 1644-1653
Kuhn K, Hashimoto S and Lotz M (2000) IL-1 beta protects human chondrocytes from CD95-induced apoptosis. Journal of Immunology 164 2233-2239
Kuhnel F, Zender L, Paul Y, Tietze MK, Trautwein C, Manns M and Kubicka S (2000) NFkB mediates apoptosis through transcriptional activation of Fas (CD95) in adenoviral hepatitis. Journal of Biological Chemistry 275 6421-6427
Kuhns DB, Priel DA and Gallin JI (2007) Induction of human monocyte interleukin (IL)-8 by fibrinogen through the Toll-like receptor pathway. Inflammation 30 178-188
Kuhtreiber WM, Hayashi T, Dale EA and Faustman DL (2003) Central role of defective apoptosis in autoimmunity. Journal of Molecular Endocrinology 31 373-399
Kuipers HF, Biesta PJ, Montagne LJ, van Haastert ES, van der Valk and van den Elsen PJ (2008) CC chemokine receptor 5 (CCR5) gene promoter activation by the cyclic AMP response element binding (CREB) transcription factor. Blood in press
Kukan M (2004) Emerging roles of proteasomes in ischemia-reperfusion injury of organs. Journal of Physiology and Pharmacology 55 3-15
Kukreja P, Abdel-Mageed AB, Mondal D, Liu K and Agrawal KC (2005) Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kB activation. Cancer Research 65 9891-9898
Kuldo JM, Ogawara KI, Werner N, Asgeirsdottir SA, Kamps JA, Kok RJ and Molema G (2005) Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases. Current Vascular Pharmacology 3 11-39
Kuldo JM, Westra J, Asgeirsdottir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC and Molema G (2005) Differential effects of NF-kB and p38 MAPK inhibitors and combinations thereof on TNF{alpha} and IL-1b induced pro-inflammatory status of endothelial cells in vitro. American Journal of Physiology: Cell Physiology 289 C1229-C1239
Kulka M, Alexopoulou L, Flavell RA and Metcalfe DD (2004) Activation of mast cells by double-stranded RNA: Evidence for activation through Toll-like receptor 3. Journal of Allergy and Clinical Immunology 114 174-182
Kulms D and Schwarz T (2006) NF-kB and cytokines. Vitamins and Hormones 74C 283-300
Kumagai N, Ohno K, Tameshige R, Hoshijima M, Yogo K, Ishida N and Takeya T (2004) Induction of mouse c-src in RAW264 cells is dependent on AP-1 and NF-kB and important for progression to multinucleated cell formation. Biochemical and Biophysical Research Communications 325 758-768
Kumagai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M and Uchida K (2004) A lipid peroxidation-derived inflammatory mediator: Identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages. Journal of Biological Chemistry 279 48389-48396
Kumar A and Boriek AM (2003) Mechanical stress activates the nuclear factor-kB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy. FASEB Journal 17 386-396
Kumar A, Dhawan S and Aggarwal BB (1998) Emodin (3-methyl-1,6,8-trihydroxyanthaquinone) inhibits TNF-induced NF-kB activation, IkB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells. Oncogene 17 913-918
Kumar A, Dhawan S, Hardegen NJ and Aggarawal BB (1998) Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of Nuclear Factor-kB activation. Biochemical Pharmacology 55 775-783
Kumar A, Dhawan S, Mukhopadhyay A and Aggarwal BB (1999) Human immunodeficiency virus-1-tat induces matrix metalloproteinase-9 in monocytes through protein tyrosine phosphatase-mediated activation of nuclear transcription factor NF-kB. FEBS Letters 462 140-144
Kumar A, Haque J, Lacoste J, Hiscott J and Williams BRG (1994) Double-stranded RNA-dependent protein kinase activates transcription factor NF-kB by phosphorylating IkB. Proceedings of the National Academy of Sciences USA 91 6288-6292
Kumar A, Hawkins KS, Hannan MA and Ganz MB (2001) Activation of PKC-beta(I) in glomerular mesangial cells is associated with specific NF-kB subunit translocation. American Journal of Physiology: Renal Physiology 281 F613-F619
Kumar A, Jasmin A, Eby MT and Chaudhary PM (2001) Cytotoxicity of Tumor necrosis factor related apoptosis-inducing ligand towards Ewing’s sarcoma cell lines. Oncogene 20 1010-1014
Kumar A, Knox AJ and Boriek AB (2003) CCAAT/enhancer-binding protein and activator protein-1 transcription factors regulate the expression of interleukin-8 through the mitogen-activated protein kinase pathways in response to mechanical stretch. Journal of Biological Chemistry 278 18868-18876
Kumar A, Kumar A, Michael P, Brabant D, Parissenti AM, Ramana CV, Xu X and Parrillo JE (2005) Human serum from patients with septic shock activates transcription factor STAT1, IRF1 and NF-kB and induces apoptosis in human cardiac myocytes. Journal of Biological Chemistry 280 42619-42626
Kumar A, Lin Z, Senbanerjee S and Jain MK (2005) Tumor necrosis factor alpha-mediated reduction of KLF2 is due to inhibition of MEF2 by NF-kB and histone deacetylases. Molecular and Cellular Biology 25 5893-5903
Kumar A, Lnu S, Malya R, Barron D, Moore J, Corry DB and Boriek AM (2003) Mechanical stretch activates nuclear factor-kB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma. FASEB Journal 17 1800-1811
Kumar A, Malik F, Bhushan S, Sethi VK, Shahi AK, Kaur J, Taneja SC, Qazi GN and Singh J (2007) An essential oil and its major constituent isointermedeol induce apoptosis by increased expression of mitochondrial cytochrome c and apical death receptors in human leukaemia HL-60 cells. Chem Biol Interactions in press
Kumar A, Murphy R, Robinson P, Wei L and Boriek AM (2004) Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-kB transcription factor. FASEB Journal 18 1524-1535
Kumar A, Sinha RA, Tiwari M, Singh R, Koji T, Manhas N, Rastogi L, Pal L, Shrivastava A, Sahu RP and Godbole MM (2007) Hyperthyroidism induces apoptosis in rat liver through activation of death receptor-mediated pathways. Journal ofHepatology 46 888-898
Kumar A, Takada Y, Boriek AM and Aggarwal BB (2004) Nuclear factor-kB: its role in health and disease. Journal of Molecular Medicine 82 434-448
Kumar A, Tassopoulos AM, Li Q and Yu FS (2007) Staphylococcus aureus protein A induced inflammatory response in human corneal epithelial cells. Biochemical and Biophysical Research Communications 354 955-961
Kumar A, Upadhyay G, Modi DR and Singh MP (2007) The involvement of secondary signaling molecules in cytochrome P-450 1A1-mediated inducible nitric oxide synthase expression in benzo(a)pyrene-treated rat polymorphonuclear leukocytes. Life Sciences in press
Kumar A, Wu H, Collier-Hyams LS, Hansen JM, Li T, Yamaoah K, Pan ZQ, Jones DP and Neish AS (2007) Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO Journal 26 4457-4466
Kumar A, Yang Y-L, Flati V, Der S, Kadereit S, Deb A, Haque J, Reis L, Weissmann C and Williams BRG (1997) Deficient cytokine signaling mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kB. EMBO Journal 16 406-416
Kumar A, Yin J, Zhang J and Yu FS (2007) Modulation of corneal epithelial innate immune response to pseudomonas infection by flagellin pretreatment. InvestigativeOphthalmology & Visual Science 48 4664-4670
Kumar A, Zhang J and Yu FS (2004) Innate immune response of corneal epithelial cells to Staphylococcus aureus infection: role of peptidoglycan in stimulating proinflammatory cytokine secretion. Investigative Ophthalmology and Visual Science 45 3513-3522
Kumar A, Zhang J and Yu FS (2006) Toll-like receptor 2-mediated expression of beta-defensin-2 in human corneal epithelial cells. Microbes and Infection 8 380-389
Kumar A, Zhang J and Yu FS (2006) Toll-like receptor 3 agonist poly(I:C)-induced antiviral response in human corneal epithelial cells. Immunology 117 11-21
Kumar B, Husain SA and Chandra B (2005) Constitutive activation of nuclear factor-kB: preferential homodimerization of p50 subunits in cervical carcinoma. Frontiers in Bioscience 10 1510-1519
Kumar B, Kumar A, Pandey BN, Hazra B and Mishra KP (2008) Increased cytotoxicity by the combination of radiation and diospyrin diethylether in fibrosarcoma in culture and in tumor. International Journal of Radiation Biology 84 429-440
Kumar D, Gokhale P, Broustas C, Chakravarty D, Ahmad I and Kasid U (2004) Expression of SCC-S2, an antiapoptotic molecule, correlates with enhanced proliferation and tumorigenicity of MDA-MB 435 cells. Oncogene 23 612-616
Kumar H, Kawai T, Kato H, Sato S, Takahashi K, Coban C, Yamamoto M, Uematsu S, Ishiii KJ, Takeuchi O and AKira S (2006) Essential role of IPS-1 in innate immune responses against RNA viruses. Journal of Experimental Medicine 203 1795-1803
Kumar KA, Rajgopal Y, Pillai U and Babu PP (2003) Activation of nuclear transcription factor-kB is associated with the induction of inhibitory kB kinase-beta and involves differential activation of protein kinase C and protein tyrosine kinases during fatal murine cerebral malaria. Neuroscience Letters 340 139-142
Kumar R, Singh PK, Sharma A, Prasad J, Sagar R, Singh S, Arora R and Sharma RK (2005) Podophyllum hexandrum extract provides radioprotection by modulating the expression of proteins associated with apoptosis. Biotechnology and Applied Biochemistry 42 81-92
Kumar S, Blake SM and Emery JG (2001) Intracellular signaling pathways as a target for the treatment of rheumatoid arthritis. Current Opinion in Pharmacology 1 307-313
Kumar S and Gélinas C (1993) IkBa-mediated inhibition of v-Rel DNA-binding requires direct interaction with the RxxRxRxxC Rel/kB DNA-binding motif. Proceedings of the National Academy of Sciences USA 90 8962-8966
Kumar S, Rabson AB and Gelinas C (1992) The RxxRxRxxC motif conserved in all Rel/kB proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein. Molecular and Cellular Biology 12 3094-3106
Kumar S, Sharma A, Madan B, Singhal V and Ghosh B (2007) Isoliquiritigenin inhibits IkB kinase activity and ROS generation to block TNF-a induced expression of cell adhesion molecules on human endothelial cells. Biochemical Pharmacology 73 1602-1612
Kumar S, Singh BK, Pandey AK, Kumar A, Sharma SK, Raj HG, Prasad AK, Eycken EV, Parmar VS and Ghosh B (2007) A chromone analog inhibits TNF-alpha induced expression of cell adhesion molecules on human endothelial cells via blocking NF-kB activation.Bioorganic Medicinal Chemistry 15 2952-2962
Kumar S, Singhal V, Roshan R, Sharma A, Rembhotkar GW and Ghosh B (2007) Piperine inhibits TNF-a induced adhesion of neutrophils to endothelial monolayer through suppression of NF-kB and IkB kinase activation. European Journal of Pharmacology inpress
Kumar U, Chen J, Sapoznikhov V, Canteros G, White BH and Sidhu A (2005) Overexpression of inducible nitric oxide synthase in the kidney of the spontaneously hypertensive rat. Clinical and Experimental Hypertension 27 17-31
Kumar Mangalam A, Aggarwal A and Naik S (2002) Gold sodium thiomalate (GSTM) inhibits lipopolysaccharide stimulated tumor necrosis factor-alpha through ceramide pathway. Cellular Immunology 219 1-10
Kumar Mitra A and Krishna M (2004) In vivo modulation of signaling factors involved in cell survival. Journal of Radiation Research (Tokyo) 45 491-495
Kumar-Sinha C, Varambally S, Sreekumar A and Chinnaiyan AM (2002) Molecular cross-talk between the TRAIL and interferon signaling pathways. Journal of Biological Chemistry 277 575-585
Kumamoto H and Ooya K (2005) Expression of tumor necrosis factor alpha, TNF-related apoptosis-inducing ligand, and their associated molecules in ameloblastomas. Journal of Oral Pathology and Medicine 34 287-294
Kumwenda ZL, Wong CB, Johnson JA, Gosnell JE, Welch WJ and Harris HW (2002) Chylomicron-bound endotoxin selectively inhibits NF-kB activation in rat hepatocytes. Shock 18 182-188
Kun JF (2003) Regulation of nitrogen monoxide production in human malaria. Redox Reports 8 289-291
Kunath K, von Harpe A, Petersen H, Fischer D, Voigt K, Kissel T and Bickel U (2002)The structure of PEG-modified poly(ethylene imines) influences biodistribution and pharmacokinetics of their complexes with NF-kB decoy in mice. Pharmaceutical Research 19 810-817
Kundu JK, Mossanda KS, Na HK and Surh YJ (2005) Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets. Cancer Letters 218 21-31
Kundu JK, Shin YK and Surh YJ (2006) Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kB in mouse skin by blocking IkB kinase activity. Carcinogenesis 27 1465-1474
Kundu JK, Shin YK and Surh YJ (2006) Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kB and AP-1 as prime targets. Biochemical Pharmacology in press
Kundu JK and Surh YJ (2004) Molecular basis of chemoprevention by resveratrol: NF-kB and AP-1 as potential targets. Mutation Research 555 65-80
Kundu JK and Surh YJ (2005) Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals. Mutation Research 591 123-146
Kundu JK and Surh YJ (2007) Epigallocatechin gallate inhibits phorbol ester-induced activation of NF-kB and CREB in mouse skin: role of p38 MAPK. Annals of the New York Academy of Sciences 1095 504-512
Kundu M, Ansari SA, Chepenik LG, Pomerantz RJ, Khalili K, Rappaport J and Amini S (1999) HIV-1 regulatory protein tat induces RNA binding proteins in central nervous system cells that associate with the viral trans-acting-response regulatory motif. Journal of Human Virology 2 72-80
Kundu M, Guermah M, Roeder RG, Amini S and Khalili K (1997) Interaction between cell cycle regulator, E2F-1, and NF-kB mediates repression of HIV-1 gene transcription. Journal of Biological Chemistry 272 29468-29526
Kung CP and Raab-Traub N (2008) Epstein-Barr virus latent membrane protein 1 induces expression of the epidermal growth factor receptor through effects on Bcl-3 and STAT3. Journal of Virology 82 5486-5493
Kunigal S, Lakka SS, Joseph P, Estes N and Rao JS (2008) Matrix metalloproteinase-9 inhibition down-regulates radiation-induced nuclear factor-kB activity leading to apoptosis in breast tumors. Clinical Cancer Research 14 3617-3626
Kunisawa J, Gohda M, Kurashima Y, Ishikawa I, Higuchi M and Kyono H (2008) Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NFkB-inducing kinase in stromal cells. Blood 111 4646-4652
Kunnumakkara AB, Diagaradjane P, Guha S, Deonukhkar A, Shentu S, Aggarwal BB and Krishnan S (2008) Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kB-regulated gene products. Clinical Cancer Research 14 2128-2136
Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J and Aggarwal BB (2007) Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kB-regulated gene products. Cancer Research 673853-3861
Kunnumakkara AB, Nair AS, Ahn KS, Pandey MK, Yi Z, Liu M and Aggarwal BB (2007)Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1 mediated NF-kB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Bloodin press
Kuno K, Ishikawa Y, Ernst MK, Ogata M, Rice NR, Mukaida N and Matsushima K (1995) Identification of an IkBa-associated kinase in a human monocytic cell line and determination of its phosphorylation sites on IkBa. Journal of Biological Chemistry 270 27914-27919
Kuno K, Sukegawa K, Ishikawa Y, Orii T and Matsushima K (1994) Acid sphingomyelinase is not essential for IL-1 and TNF receptor signaling pathway leading to NFkB activation. International Immunology 6 1269-1272
Kunsch C and Rosen CA (1993) NF-kB subunit-specific regulation of the interleukin-8 promoter. Molecular and Cellular Biology 13 6137-6146
Kunsch C, Lang RK, Rosen CA and Shannon MF (1994) Synergistic transcriptional activation of the IL-8 gene by NF-kB p65 (RelA) and NF-IL-6. Journal of Immunology 153 153-164
Kunsch C, Luchoomun J, Chen X, Dodd G, Karu K, Meng C, Marino E, Olliff L, Piper JD, Qiu FH, Sikorski J, Somers P, Suen KL, Thomas S, Whalen A, Wasserman M and Sundell C (2005) AGIX-4207, a novel antioxidant and anti-inflammatory compound: I. Cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression. Journal of Pharmacology and Experimental Therapeutics 313 492-501
Kunsch C, Luchoomun J, Grey JY, Olliff LK, Saint LB, Arrendale RF, Wasserman MA, Saxena U and Medford RM (2004) Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel, antioxidant and anti-inflammatory agent. Journal of Pharmacology and Experimental Therapeutics 308 820-829
Kunsch C, Ruben SM and Rosen CA (1992) Selection of optimal kB/Rel DNA-binding motifs: interaction of both subunits of NF-kB with DNA is required for transcriptional activation. Molecular and Cellular Biology 12 4412-4421
Kunter Y, Daniel S, Arvelo MB, Choi J, Shukri T, Patel VI, Longo CR, Scali ST, Shrikhande G, Rocha E, Czismadia E, Mottley C, Grey ST, Floege J and Ferran C (2005) Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells. Kidney International 68 1520-1532
Kuntzen C, Zazzeroni F, Pham CG, Papa S, Bubici C, Knabb JR and Franzoso G (2007) A method for isolating prosurvival targets of NF-kB/Rel transcription factors. Methods in Molecular Biology 399 99-124
Kunugiza Y, Tomita T, Tomita N, Morishita R and Yoshikawa H (2006) Inhibitory effect of ribbon-type NF-kB decoy oligodeoxynucleotides on osteoclast induction and activity in vitro and in vivo. Arthritis Research & Therapy 8 R103
Kunz A, Abe T, Hochrainer K, Shimamura M, Anrather J, Racchumi G, Zhou P and Iadecola C (2008) Nuclear factor-kB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion. Journal of Neuroscience 28 1649-1658
Kunz D, Walker G, Eberhardt W, Nitsch D and Pfeilschifter J (1995) Interleukin 1b-induced expression of nitric oxide synthease in rat renal mesangial cells is suppressed by cyclosporin A. Biochemical and Biophysical Research Communications 216 438-446
Kunz M, Blo G, Gillitzer R, Gross G, Goebeler M, Rapp UR and Ludwig S (2002) Hypoxia/reoxygenation-induction of monocyte chemoattractant protein -1 in melanoma cells. Involvement of NF-kB and SP-1 transcription factors and mitogen activated protein kinase pathways. Biochemical Journal 366 299-306
Kunz M, Bloss G, Gillitzer R, Gross G, Goebeler M, Rapp UR and Ludwig S (2002) Hypoxia/reoxygenation-induction of monocyte chemoattractant protein -1 in melanoma cells. Involvement of NF-kB and SP-1 transcription factors and mitogen activated protein kinase pathways. Biochemical Journal 366 299-306
Kunz M, Hartmann A, Flory E, Toksoy A, Koczan D, Thiesen HJ, Mukaida N, Neumann M, Rapp UR, Brocker EB and Gillitzer R (1999) Anoxia-induced up-regulation of interleukin-8 in human malignant melanoma. A potential mechanism for high tumor aggressiveness. American Journal of Pathology 155 753-763
Kuo AH, Stoica GE, Riegel AT and Wellstein A (2007) Recruitment of insulin receptor substrate-1 and activation of NF-kB essential for midkine growth signaling through anaplastic lymphoma kinase. Oncogene 26 859-869
Kuo CC, Lin WT, Liang CM and Liang SM (2006) Class I and III phosphatidylinositol 3′-kinase play distinct roles in TLR signaling pathway. Journal of Immunology 176 5943-5949
Kuo CL, Ho FM, Chang MY, Prakash E and Lin WW (2007) Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase. Journal of Cellular Biochemistry in press
Kuo CT and Leiden JM (1999) Transcriptional regulation of T lymphocyte development and function. Annual Review of Immunology 17 149-187
Kuo HP, Wang CH, Huang KS, Lin HC, Yu CT, Liu CY and Lu LC (2000) Nitric oxide modulates interleukin-1beta and tumor necrosis factor-alpha synthesis by alveolar macrophages in pulmonary tuberculosis. American Journal of Respiratory Critical Care Medicine 161 192-199
Kuo MC, Weng CY, Ha CL and Wu MJ (2005) Ganoderma lucidum mycelia enhance innate immunity by activating NF-kB. Journal of Ethnopharmacology 103 217-222
Kuo MT, Liu Z, Wei Y, Lin-Lee YC, Tatebe S, Mills GB and Unate H (2002) Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kB signaling. Oncogene 21 1945-1954
Kuo PL, Hsu YL, Lin TC, Tzeng WS, Chen YY and Lin CC (2006) Rugosin E, an ellagitannin, inhibits MDA-MB-231 human breast cancer cell proliferation and induces apoptosis by inhibiting nuclear factor-kB signaling pathway. Cancer Letters 2248 280-291
Kuo SH, Chen LT, Yeh KH, Wu MS, Hsu HC, Yeh PY, Mao TL, Chen CL, Doong SL, Lin JT and Cheng AL (2004) Nuclear expression of BCL10 or nuclear factor kB predicts Helicobacter pylori-independent status of early-stage, high-grade gastric mucosa-associated lymphoid tissue lymphomas. Journal of Clinical Oncology 22 3491-3497
Kuo SH, Yeh PY, Chen LT, Wu MS, Lin CW, Yeh KH, Tzeng YS, Chen JY, Hsu PN, Lin JT and Cheng AL (2008) Overexpression of B-cell activating factor of TNF family (BAFF) is associated with Helicobacter pylori-independent growth of gastric diffuse large B-cell lymphoma with histologic evidence of MALT lymphoma. Blood in press
Kuo YR, Wang FS, Jeng SF, Lutz BS, Huang HC and Yang KD (2004) Nitrosoglutathione promotes flap survival via suppression of reperfusion injury-induced superoxide and inducible nitric oxide synthase induction. Journal of Trauma 57 1025-1031
Kupatt C, Habazettl H, Goedecke A, Wolf DA, Zahler S, Boekstegers P, Kelly RA and Becker BF (1999) Tumor necrosis factor-alpha contributes to ischemia- and reperfusion-induced endothelial activation in isolated hearts. Circulation Research 84 392-400
Kupatt C, Hinkel R, Vachenauer R, Horstkotte J, Raake P, Sandner T, Kreuzpointner R, Muller F, Dimmeler S, Feron O and Boekstegers P (2003) VEGF165 transfection decreases postischemic NF-kB-dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation. FASEB Journal 17 705-707
Kupatt C, Wichels R, Deiss M, Molnar A, Lebherz C, Raake P, von Degenfeld G, Hahnel D and Boekstegers P (2002) Retroinfusion of NFkB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs. Gene Therapy 9 518-526
Kupfer R, Lang J, Williams-Skipp C, Nelson M, Bellgrau D and Schienman RI (2006) Loss of a gimap/ian gene leads to activation of NF-kB through a MAPK-dependent pathway. Molecular Immunology 44 479-487
Kupfer R and Scheinman RI (2002) Measurement of IKK activity in primary rat T cells: rapid activation and inactivation. Journal of Immunological Methods 266 155-164
Kuphal S, Poser I, Jobin C, Hellerbrand C and Bosserhoff AK (2004) Loss of E-cadherin leads to upregulation of NFkB activity in malignant melanoma. Oncogene 23 8509-8519
Kuprash DV, Rice NR and Nedospasov SA (1995) Homodimer of p50 (NFkB1) does not introduce a substantial directed bend into DNA according to three different experimental assays. Nucleic Acids Research 23 427-433
Kuprash DV, Udalova IA, Turetskaya RL, Kwiatkowski D, Rice NR and Nedospasov SA (1999) Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide. Journal of Immunology 162 4045-4052
Kuprash DV, Udalova TA, Turetskaya RL, Rice NR and Nedospasov SA (1995) Conserved kB element located downstream of the tumor necrosis factor a gene: distinct NF-kB binding pattern and enhancer activity in LPS activated murine macrophages. Oncogene 11 97-106
Kuramoto T, Nishikawa M, Thanaketpaisarn O, Okabe T, Yamashita F and Hashida M (2005) Use of lipoplex-induced nuclear factor-kB activation to enhance transgene expression by lipoplex in mouse lung. Journal of Gene Medicine 8 53-62
Kurata S and Yamamoto N (1999) Glucocorticoid can reduce the transcriptional activation of HIV-1 promoter through the reduction of active NF-kB. Journal of Cellular Biochemistry 76 13-19
Kurata S, Wakabayashi T, Ito Y, Miwa N, Ueno R, Marunouchi T and Kurata N (1993) Human neuroblastoma cells produce the NF-kB-like HIV-1 transcription activator during differentiation. FEBS Letters 321 201-204
Kurban S, Akpinar Z and Mehmetoglu I (2008) Receptor activator of nuclear factor kB ligand (RANKL) and osteoprotegerin levels in multiple sclerosis. Multiple Sclerosis in press
Kurbanov BM, Fecker LF, Geilen CC, Sterry W and Eberle J (2007) Resistance of melanoma cells to TRAIL does not result from upregulation of antiapoptotic proteins by NF-kB but is related to downregulation of initiator caspases and DR4. Oncogene in press
Kurebayashi S, Xu X, Ishii S, Shiraishi M, Kouhara H and Kasayama S (2005) A novel thiazolidinedione MCC-555 down-regulates tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1 in vascular endothelial cells.Atherosclerosis 182 71-77
Kurexi Y, Huang GH, Long M, He J, Nasier M, Xia YP and Hamulati W (2007) Construction of NF-kB siRNA expression vector [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 32 765-770
Kurihara N, Hiruma Y, Zhou H, Subler MA, Dempster DW, Singer FR, Reddy SV, Gruber HE, Windle JJ and Roodman GD (2007) Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. Journal of ClinicalInvestigation 117 133-142
Kurihara N, Reddy SV, Menaa C, Anderson D and Roodman GD (2000) Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype. Journal of Clinical Investigation 105 607-614
Kurland JF and Meyn RE (2001) Protease inhibitors restore radiation-induced apoptosis to Bcl-2-expressing lymphoma cells. International Journal of Cancer 20 327-333
Kurland JF, Kodym R, Story MD, Spurgers KB, McDonnell TJ and Meyn RE (2001) NF-kB1 (p50) homodimers contribute to transcription of the bcl-2 oncogene. Journal of Biological Chemistry 276 45380-4538
Kurland JF, Voehringer DW and Meyn RE (2003) The MEK/ERK pathway acts upstream of NF-kB1 (p50) homodimer activity and Bcl-2 expression in a murine B-Cell lymphoma cell line: MEK inhibition restores radiation-induced apoptosis. Journal of Biological Chemistry 278 32465-32470
Kuroda K, Horiguchi Y, Nakashima J, Kikuchi E, Kanao K, Miyajima A, Ohigashi T, Umezawa K and Murai M (2005) Prevention of cancer cachexia by a novel nuclear factor kB inhibitor in prostate cancer. Clincal Cancer Research 11 5590-5594
Kuroda Y, Hisatsune C, Nakamura T, Matsuo K and Mikoshiba K (2008) Osteoblasts induce Ca2+ oscillation-independent NFATc1 activation during osteoclastogenesis. Proceedings of the National Academy of Sciences USA in press
Kuroishi T, Endo Y, Muramoto K and Sugarawa S (2008) Biotin deficiency up-regulates TNF-a production in murine macrophages. Journal of Leukocyte Biology in press
Kurokawa M, Brown J, Kagawa Y and Shiraki K (2003) Cytokine-regulatory activity and therapeutic efficacy of cinnamyl derivatives in endotoxin shock. European Journal of Pharmacology 474 283-293
Kurokawa M, Ghosh SK, Ramos JC, Mian AM, Toomey NL, Cabral L, Whitby D, Barber GN, Dittmer DP and Harrington Jr WJ (2005) Azidothymidine inhibits NF-kB and induces Epstein-Barr virus gene expression in Burkitt lymphoma. Blood 106 235-240
Kuroki H, Morisaki T, Matsumoto K, Onishi H, Baba E, Tanaka M and Katano M (2003) Streptococcal preparation OK-432: a new maturation factor of monocyte-derived dendritic cells for clinical use. Cancer Immunology and Immunotherapy 52 561-568
Kurokouchi K, Jacobs CR and Donahue HJ (2001) Oscillating fluid flow inhibits TNF-a-induced NF-kB activation via an IkB kinase pathway in osteoblast-like UMR106 cells. Journal of Biological Chemistry 276 13499-134504
Kurozumi R and Kojima S (2005) Increase of intracellular glutathione by low-level NO mediated by transcription factor NF-kB in RAW 264.7 cells. Biochimica et Biophysica Acta 1744 58-67
Kurpius D, Wilson N, Fuller L, Hoffman A and Dailey ME (2006) Early activation, motility, and homing of neonatal microglia to injured neurons does not require protein synthesis. Glia 54 58-70
Kurt RA, Urba WJ, Smith JW and Schoof DD (1998) Peripheral T lymphocytes from women with breast cancer exhibit abnormal protein expression of several signaling molecules. International Journal of Cancer 78 16-20
Kurtovic J and Segal I (2004) Recent advances in biological therapy for inflammatory bowel disease. Tropical Gastroenterology 25 9-14
Kury P, Schroeter M and Jander S (2004) Transcriptional response to circumscribed cortical brain ischemia: spatiotemporal patterns in ischemic vs. remote non-ischemic cortex. European Journal of Neuroscience 19 1708-1720
Kurzrock R, Talpaz M, Li L and Estrov Z (2006) Distinct biological impact of dephosphorylation vs. downregulation of p210Bcr-Abl: Implications for imatinib mesylate response and resistance. Leukemia and Lymphoma 47 1651-1664
Kusaka M, Yamada K, Kuroyanagi Y, Terauchi A, Kowa H, Kurahashi H and Hoshinaga K (2005) Gene expression profile in rat renal isografts from brain dead donors.Transplantation Proceedings 37 364-366
Kusagawa S, Imamura Y, Yasuoka A, Hoshino H, Oka S and Takebe Y (2003) Identification of HIN type 2 subtype B transmission in East Africa. AIDS Research & Human Retroviruses 19 1045-1049
Kushner DB and Ricciardi RP (1999) Reduced phosphorylation of p50 is responsible for diminished NF-kB binding to the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells. Molecular and Cellular Biology 19 2169-2179
Kushner DB, Pereira DS, Liu X, Graham FL and Riciardi RP (1996) The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kB to the MHC class I enhancer in transformed cells. Oncogene 12 143-151
Kusmic C, Basta G, Lazzerini G, Vesentini N and Barsacchi R (2004) The effect of ginkgo biloba in isolated ischemic/reperfused rat heart: a link between vitamin E preservation and prostaglandin biosynthesis. Journal of Cardiovascular Pharmacology44 356-362
Kusminski CM, da Silva NF, Creely SJ, Fisher FM, Harte AL, Baker AR, Kumar S and McTernan PG (2007) The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes. Journal of Clinical Endocrinology and Metabolism 92 270-276
Kustermans G, El Benna J, Piette J and Legrand-Poels S (2004) Perturbation of actin dynamics induces NF-kB activation in myelomonocytic cells via a NADPH oxidase-dependent pathway. Biochemical Journal 387 531-540
Kustermans G, Piette J and Legrand-Poels S (2008) Actin-targeting natural compounds as tools to study the role of actin cytoskeleton in signal transduction. Biochemical Pharmacology in press
Kusomoto H, Haraguchi M, Nozuka Y, Oda Y, Tsuneyoshi M and Iguchi H (2006) Characteristic features of disseminated carcinomatosis of the bone marrow due to gastric cancer: The pathogenesis of bone destruction. Oncology Reports 16 735-740
Kusumoto Y, Hirano H, Saitoh K, Yamada S, Takedachi M, Nozaki T, Ozawa Y, Nakahira Y, Saho T, Ogo H, Shimabukuro Y, Okada H and Murakami S (2004) Human gingival epithelial cells produce chemotactic factors interleukin-8 and monocyte chemoattractant protein-1 after stimulation with Porphyromonas gingivalis via toll-like receptor 2. Journal of Periodontology 75 370-379
Kutlu B, Darville MI, Cardozo AK and Eizirik DL (2003) Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells. Diabetes 52 348-355
Kutlu B, Naamane N, Berthou L and Eizirik DL (2004) New approaches for in silico identification of cytokine-modified beta cell gene networks. Annals of the New York Academy of Sciences 1037 41-58
Kutuk O and Basaga H (2003) Inflammation meets oxidation: NF-kB as a mediator of initial lesion development in atherosclerosis. Trends in Molecular Medicine 9 549-557
Kutuk O and Basaga H (2003) Aspirin prevents apoptosis and NF-kB activation induced by H2O2 in Hela cells. Free Radical Research 37 1267-1276
Kutuk O and Basaga H (2004) Aspirin inhibits TNFalpha- and IL-1-induced NF-kB activation and sensitizes HeLa cells to apoptosis. Cytokine 25 229-237
Kutz H, Reisbach G, Schultheiss U and Kieser A (2007) The c-Jun N-terminal kinase pathway is critical for cell transformation by the latent membrane protein 1 of Epstein-Barr virus. Virology in press
Kuwabara N, Tamada S, Iwai T, Teramoto K, Kaneda N, Yukimura T, Nakatani T and Miura K (2006) Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy.Urology 67 440-446
Kuwahara I, Lillehoj EP, Lu W, Singh IS, Isohama Y, Miyata T and Kim KC (2006) Neutrophil elastase induces IL-8 gene transcription and protein release through p38/NF-kB activation via EGFR transactivation in a lung epithelial cell line.American Journal of Physiology: Lung Cell and Molecular Physiology 291 L407-L416
Kuwata H, Matsumoto M Atarashi K, Morishita H, Hirotoni T, Koga R and Takeda K (2006) IkBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation. Immunity 24 41-51
Kuwata H, Watanabe Y, Miyoshi H, Yamamoto M, Kaisho T, Takeda K and Akira S (2003) IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-a production in macrophages. Blood 102 4123-4129
Kuwayama Y, Suzuki T, Moriuchi S, Glorioso JC and Bessho M (2005) IkB-mediated apoptotic gene therapy against acute myelogenous leukemia using replication-defective HSV-1 vector expressing tk and mutant IkBa. Cell Mol Biol (Noisy-le-grand)51 77-86
Kuzuhara T, Suganuma M, Kurusu M and Fujikai H (2007) Helicobacter pylori-secreting protein Tipalpha is a potent inducer of chemokine gene expressions in stomach cancer cells. Journal of Cancer Research and Clinical Oncology 133 287-296
Kuzuhara T, Suganuma M, Oka K and Fujiki H (2007) DNA-binding activity of TNF-a inducing protein from Helicobacter pylori.
Biochemical and Biophysical Research Communications in press
Kwak EL, Larochelle DA, Beaumont C, Torti SV and Torti FM (2005) Role for NF-kB in the regulation of ferritin H by tumor necrosis factor-a. Journal of Biological Chemistry 270 15285-15293
Kwak HB, Jin HM, Ha H, Kang MJ, Lee SB, Kim HH and Lee ZH (2005) Tumor necrosis factor-alpha induces differentiation of human peripheral blood mononuclear cells into osteoclasts through the induction of p21(WAF1/Cip1). Biochemical and Biophysical Research Communications 330 1080-1086
Kwak HB, Lee SW, Jin HM, Ha H, Lee SH, Takeshita S, Tanaka S, Kim HM, Kim HH and Lee ZH (2005) Monokine induced by interferon-gamma is induced by receptor activator of nuclear factor kB ligand and involved in osteoclast adhesion and migration. Blood 105 2963-2969
Kwak HB, Lee SW, Lee DG, Hahm KS, Kim KK, Kim HH and Lee ZH (2003) A hybrid peptide derived from cecropin-A and magainin-2 inhibits osteoclast differentiation. Life Sciences 73 993-1005
Kwak HB, Lee SW, Li YJ, Kim YA, Han SY, Jhon GJ, Kim HH and Lee ZH (2004) Inhibition of osteoclast differentiation and bone resorption by a novel lysophosphatidylcholine derivative, SCOH. Biochemical Pharmacology 67 1239-1248
Kwak HB, Yang D, Ha H, Lee JH, Kim HN, Woo ER, Lee S, Kim HH and Lee ZH (2006) Tanshinone IIA inhibits osteoclast differentiation through down-regulation of c-Fos and NFATc1. Experimental and Molecular Medicine 38 256-264
Kwak HJ, Song JS, Heo JY, Yang SD, Nam JY and Cheon HG (2005) Roflumilast inhibits lipopolysaccharide-induced inflammatory mediators via suppression of NF-kB, P38 MAP kinase and JNK activation. Journal of Pharmacology and Experimental Therapeutics 315 1188-1195
Kwak JH, Kim BH, Jung JK, Kim Y, Cho J and Lee H (2007) Structure-activity relationships of 6-hydroxy-7-methoxychroman-2-carboxylic acid N-(substituted)phenylamides as inhibitors of nuclear factor-kappaB activation. Archives of Pharmacal Research 30 1210-1215
Kwak JH, Won SW, Kim TJ, Roh E, Kang HY, Lee HW, Jung JK, Hwang BY, Kim Y, Cho J and Lee H (2008) Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect of nuclear factor-kB (NF-kB) activation. Archives of Pharmacal Research 31 133-141
Kwak SH, Wang XQ, He Q, Fang WF, Mitra S, Bdeir K, Ploplis VA, Xu Z, Kdell S, Cines D and Abraham E (2006) Plasminogen activator inhibitor-1 potentiates LPS-induced neutrophil activation through a JNK-mediated pathway. Thrombosis and Haemostosis 95 829-835
Kwak YT, Guo J, Shen J and Gaynor RB (2000) Analysis of domains in the IKKa and IKKb proteins that regulate their kinase activity. Journal of Biological Chemistry 275 14752-14759
Kwak Y-T, Li R, Becerra CR, Tripathy D, Frenkel EP and Verma UN (2005) IkB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation. Journal of Biological Chemistry 280 33945-33952 (Correction JBC 280 38888)
Kwakkel J, Wiersinga WM and Boelen A (2006) Differential involvement of nuclear factor-kB and activator protein-1 pathways in the interleukin-1beta-mediated decrease of deiodinase type 1 and thyroid hormone receptor beta1 mRNA. Journal ofEndocrinology 189 37-44
Kwakkel J, Wiersinga WM and Boelen A (2007) Interleukin-1beta modulates endogenous thyroid hormone receptor alpha gene transcription in liver cells. Journal ofEndocrinology 194 257-265
Kwan Tat S, Pelletier JP, Lajeunesse D, Fahmi H, Lavigne M and Martel-Pelletier J (2008) The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cells. Clinical and Experimental Rheumatology 26 295-304
Kweon SM, Wang B, Rixter D, Lim JH, Koga T, Ishinaga H, Chen LF, Jono H, Xu H and Li JD (2006) Synergistic activation of NF-kB by nontypeable H. influenzae and S. pneumoniae is mediated by CK2, IKKb-IkBa, and p38 MAPK. Biochemical and BiophysicalResearch Communications 351 368-375
Kwiecinska P, Roszkiewicz B, Lokociejewska M and Orzechowski A (2005) Elevated expression of NF-kB and Bcl-2 proteins in C2C12 myocytes during myogenesis is affected by PD98059, LY294002 and SB203580. Cell Biology International 29 319-331
Kwok BHB, Koh B, Ndubuisi MI, Elofsson M and Crews CM (2001) The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkB kinase. Chemistry and Biology 8 759-766
Kwon AH and Qiu ZX (2007) Neutrophil elastase inhibitor prevents endotoxin-induced liver injury following experimental partial hepatectomy. British Journal of Surgery 94 609-619
Kwon AH, Qiu Z, Tsuji K, Miyaso T and Okumura T (2007) Fibronectin prevents endotoxin shock after partial hepatectomy in rats via inhibition of nuclear factor-kB and apoptosis. Experimental Biology and Medicine (Maywood) 232 895-903
Kwon BC, Sohn MH, Kim KW, Kim ES, Kim KE and Shin MH (2007) House dust mite induces expression of intercellular adhesion molecule-1 in EoL-1 human eosinophilic leukemic cells. Journal of Korean Medical Science 22 815-819
Kwon D, Fuller AC, Palma JP, Choi IH and Kim BS (2004) Induction of chemokines in human astrocytes by picornavirus infection requires activation of both AP-1 and NF-kB. Glia 45 287-296
Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW and Greene WC (2005) Lethal cutaneous disease in transgenic mice conditionally expressing HTLV-I tax. Journal of Biological Chemistry 280 35713-35722
Kwon HJ, Breese EH, Vig-Varga E, Luo Y, Lee Y, Goebl MG and Harrington MA (2004) Tumor necrosis factor alpha induction of NF-kB requires the novel coactivator SIMPL. Molecular and Cellular Biology 24 9317-9326
Kwon HJ and Kim DS (2003) Regulation of macrophage inflammatory protein-2 gene expression in response to oligodeoxynucleotide containing CpG motifs in RAW 264.7 cells. Biochemical and Biophysical Research Communications 308 608-613
Kwon HJ, Lee KW, Ho Yu S, Ho Han J and Kim DS (2003) NF-kB-dependent regulation of tumor necrosis factor-alpha gene expression by CpG-oligodeoxynucleotides. Biochemical and Biophysical Research Communications 311 129-138
Kwon HM, Choi YJ, Choi JS, Kang SW, Bae JY, Kang IJ, Jun JG, Lee SS, Lim SS and Kang YH (2007) Blockade of cytokine-induced endothelial cell adhesion molecule expression by licorice isoliquiritigenin through NF-kB signal disruption.
Experimental Biology and Medicine (Maywood) 232 235-245
Kwon HS, Brent M, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBruney MW, Marmorstein F, Greene WC and Ott M (2008) Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Cell Host Microbe 3 158-167
Kwon J, Pelletier N, DeLuca C, Genin P, Cisternas S, Lin R, Wainberg MA and Hiscott J (1998) Inducible expression of IkBa repressor mutants interferes with NF-kB activity and HIV-1 replication in Jurkat T Cells. Journal of Biological Chemistry 273 7431-7440
Kwon JA and Rho HM (2002) Hepatitis B viral core protein activates the hepatitis B viral enhancer II/pregenomic promoter through the nuclear factor kB binding site. Biochem Cell Biol 80 445-455
Kwon JH, Keates S, Simeonidis S, Grall F, Libermann TA and Keates AC (2003) ESE-1, an enterocyte-specific Ets transcription factor, regulates MIP-3alpha gene expression in Caco-2 human colonic epithelial cells. Journal of Biological Chemistry 278 875-884
Kwon KB, Kim EK, Jeong ES, Lee YH, Lee YR, Park JW, Ryu DG and Park BH (2006) Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced beta-cell damage by inhibiting NF-kB. World Journal of Gastroenterology 12 4331-4337
Kwon KB, Kim JH, Lee YR, Lee HY, Jeong YJ, Rho HW, Ryu do G, Park JW and Park BH (2003) Amomum xanthoides extract prevents cytokine-induced cell death of RINm5F cells through the inhibition of nitric oxide formation. Life Science 73 181-191
Kwon KB, Kim EK, Lim JG, Shin BC, Song YS, Seo EA, Ahn KY, Song BK and Ryu DG (2004) Sophorae radix extract inhibits high glucose-induced vascular cell adhesion molecule-1 up-regulation on endothelial cell line. Clinica Chimica Acta 348 79-86
Kwon KB, Ryu DG, Shin MK, Shin BC, Hwang WJ, Lee YR, Park JW and Park BH (2003) Fructus Benincasae Recens extract prevents cytokine-induced nitric oxide formation and cytotoxicity of RINm5F cells. Immunopharmacology and Immunotoxicology 25 615-625
Kwon KH, Barve A, Yu S, Huang MT and Kong AN (2007) Cancer chemoprevention by phytochemicals: potential molecular targets, biomarkers and animal models. Acta Pharmacologica Sinica 28 1409-1421
Kwon KS and Chae HJ (2003) Sodium salicylate inhibits expression of COX-2 through suppression of ERK and subsequent NF-kB activation in rat ventricular cardiomyocytes. Archives of Pharmacology Research 26 545-553
Kwon O, Kim KA, He L, Jung M, Ahn JS and Kim BY (2007) Complex formation of p65/RelA with nuclear Akt1 for enhanced transcriptional activation of NF-kB. Biochemical and Biophysical Research Communications in press
Kwon O, Kim KA, He L, Kim SO, Kim MS, Cha EY, Yoon BD, Sok DE, Jung M, Ahn JS and Kim BY (2008) Ionizing radiation can induce GSK-3beta phosphorylation and NF-kB transcriptional transactivation in ATM-deficient fibroblasts. Cellular Signaling in press
Kwon O, Kim KA, Kim SO, Ha R, Oh WK, Kim MS, Kim HS, Kim KD, Kim JW, Jung M, Kim CH, Ahn JS and Kim BY (2006) NF-kB inhibition increases chemosensitivity to trichostatin A-induced cell death of Ki-Ras-transformed human prostate epithelial cells. Carcinogenesis 27 2258-2268
Kwon O, Lee E, Moon TC, Jung H, Lin CX, Nam KS, Baek SH, Min HK and Chang HW (2002) Expression of cyclooxygenase-2 and pro-inflammatory cytokines induced by 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB 153) in human mast cells requires NF-kB activation. Biology and Pharmaceutical Bulletin 25 1165-1168
Kwon S, Newcomb RL a nd George SC (2001) Mechanisms of synergistic cytokine-induced nitric oxide production in human alveolar epithelial cells. Nitric Oxide 5 534-546
Kwon WJ, Kim SH, Park YO, Cho M, Kang CD, Lee G, An WG, Joo WH and Kim DW (2004) IKKg inhibits activation of NF-kB by NIK. Mol Cells 18 200-206
Kwon Y and Magnuson BA (2007) Aging alters acute apoptotic response to azoxymethane in the colon of rats. Experimental Gerontology in press
Kwon Yj, Genovesio A, Kim NY, Kim HC, Jung S, David-Watine B, Nehrbass U and Emans N (2007) High-content classification of nucleocytoplasmic import or export inhibitors.Journal of Biomolecular Screening in press
Kwon YK, Jun JM, Shin SW, Cho JW and Suh SI (2005) Curcumin decreases cell proliferation rates through BTG2-mediated cyclin D1 down-regulation in U937 cells. International Journal of Oncology 26 1597-1603
Kwon YW, Jang ER, Lee YM, Kim YS, Kwon KS, Jang HS, Oh CK and Kim KW (2000) Insulin-like growth factors II inducers interleutein-6expression via NF-kB activation in psoriasis. Biochemical and Biophysical Research Communications 278 312-317
Kwong KY, Literat A, Zhu NL, Huang HH, Li C, Jones CA and Minoo P (2004) Expression of transforming growth factor beta (TGF-beta1) in human epithelial alveolar cells: a pro-inflammatory mediator independent pathway. Life Sciences 74 2941-2957
Kye MJ, Spiess J and Blank T (2007) Transcriptional regulation of intronic calcium-activated potassium channel SK2 promoters by nuclear factor-kB and glucocorticoids.Molecular and Cellular Biochemistry in press
Kyrgidis A, Kountouras J, Zavos C and Chatzopoulos D (2005) New molecular concepts of Barrett’s esophagus: clinical implications and biomarkers. Journal of Surgical Research 125 189-212
Kyriakis JM (2001) Life-or-death decisions. Nature 414 265-266
Kyung TW, Lee JE, Shin HH and Choi HS (2008) Rutin inhibits osteoclast formation by decreasing reactive oxygen species and TNF-a by inhibiting activation of NF-kB. Experimental Molecular Medicine 40 52-58