References – F
Fabian RH, Perez-Polo JR and Kent TA (2007) A decoy oligonucleotide inhibiting nuclear factor-kappaB binding to the IgGkB consensus site reduces cerebral injury and apoptosis in neonatal hypoxic-ischemic encephalopathy. Journal ofNeuroscience Research in press
Fabis MJ, Scott GS, Kean RB, Koprowski H and Hooper DC (2007) Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models. Proceedings of the National Academy of Sciences USA 104(13):5656-61
Fabregat I, Roncero C and Fernandez M (2007) Survival and apoptosis: a dysregulated balance in liver cancer. Liver International 27 155-162
Fabisiak JP, Gao F, Thomson RG, Strieter RM, Watkins SC and Dauber JH (2006) Mycoplasma fermentans and TNF-b interact to amplify immune-modulating cytokines in human lung fibroblasts.American Journal of Physiology: Lung Cell and MolecularPhysiology 291 L781-L793
Fabre C, Carvalho G, Tasdemir E, Braun T, Ades L, Grosjean J, Boehrer S, Metivier D, Souquere S, Pierron G, Fenaux P and Kroemer G (2007) NF-kB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia. Oncogene in press
Facchetti F, Vermi W, Fiorentini S, Chilosi M, Caruso A, Duse M, Notarangelo LD and Badolato R (1999) Expression of inducible nitric oxide synthase in human granulomas and histiocytic reactions. American Journal of Pathology 154 145-152
Facchini A, Borzi RM, Marcu KB, Stefanelli C, Olivotto E, Goldring MB, Facchini A and Flamigni F (2005) Polyamine depletion inhibits NF-kB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-a. Journal of Cell Physiology in press
Faccio R, Takeshita S, Zallone A, Ross FP and Teitelbaum SL (2003) c-Fms and the alpha(v)beta(3) integrin collaborate during osteoclast differentiation. Journal of Clinical Investigation 111 749-758
Factor V, Oliver AL, Panta GR, Thorgeirsson SS, Sonenshein GE and Arsura M (2001) Roles of Akt/PKB and IKK complex in constitutive induction of NF-kB in hepatocellular carcinomas of transforming growth factor alpha/c-myc transgenic mice. Hepatology 34 32-41
Fagerlund R, Kinnunen L, Kohler M, Julkunen I and Melen K (2005) NF-kB is transported into the nucleus by importin alpha 3 and importin alpha 4. Journal of Biological Chemistry in press
Fagerlund R, Melen K, Cao X and Julkunen I (2008) NF-kB p52, RelB and c-Rel are transported into the nucleus via a subset of importin alpha molecules. Cellular Signaling in press
Faggioli L, Costanzo C, Donadelli M and Palmieri M (2004) Activation of the interleukin-6 promoter by a dominant negative mutant of c-Jun. Biochimica et Biophyscia Acta 1692 17-24
Fahy BN, Schlieman M, Virudachalam S and Bold RJ (2003) AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2. British Journal of Cancer 89 391-397
Fahy BN, Schlieman MG, Virudachalam S and Bold RJ (2004) Inhibition of AKT abrogates chemotherapy- induced NF-kB survival mechanisms: implications for therapy in pancreatic cancer. Journal of the American College of Surgeons 198 591-599
Fahmi H, Di Battista JA, Pelletier JP, Mineau F, Ranger P and Martel-Pelletier J (2001) Peroxisome proliferator-activated receptor gamma activators inhibit interleukin-1beta-induced nitric oxide and matrix metalloproteinase 13 production in human chondriocytes. Arthritis and Rheumatism 44 595-607
Fahrig T, Gerlach I and Horvath E (2005) A synthetic derivative of the natural product rocaglaol is a potent inhibitor of cytokine-mediated signaling and shows neuroprotective activity in vitro and in animal models of Parkinson’s Disease and traumatic brain injury. Molecular Pharmacology 67 1544-1555
Fahy BN, Schlieman MG, Mortenson MM, Virudachalam S and Bold RJ (2005) Targeting BCL-2 overexpression in various human malignancies through NF-kB inhibition by the proteasome inhibitor bortezomib. Cancer Chemother Pharmacol 56 46-54
Fahy RJ, Exline MC, Gavrilin MA, Bhatt NY, Besecker BY, Sarkar A, Hollyfield JL, Duncan MD, Nagaraja HN, Knatz NL, Hall M and Wewers MD (2008) Inflammasome mRNA expression in human monocytes during early septic shock. American Journal of Respiratory Critical Care Medicine in press
Fain JN and Madan AK (2005) Regulation of monocyte chemoattractant protein 1 (MCP-1) release by explants of human visceral adipose tissue. International Journal of Obesity 29 1299-1307
Fairchild KD, Singh IS, Carter HC, Hester L and Hasday JD (2005) Hypothermia enhances phosphorylation of IkB kinase andprolongs nuclear localization of NF-kB in LPS-activated macrophages.American Journal of Physiology: Cell Physiology 289 C1114-C1121
Fairchild KD, Singh IS, Patel S, Drysdale BE, Viscardi RM, Hester L, Lazusky HM and Hasday JD (2004) Hypothermia prolongs activation of NF-kB and augments generation of inflammatory cytokines. American Journal of Physiology: Cellular Physiology 287 C422-C431
Fairhead T, Lian D, McCully ML, Garcia B, Zhong R and Madrenas J (2008) RIP2 is required for NOD signaling but not for Th1 cell differentiation and cellular allograft rejection. American Journal of Transplantation 8 1143-1150
Faisal A, Saurin A, Gregory B, Foxwell B and Parker PJ (2008) The scaffold MYD88 acts to couple protein kinase Cepsilon to Toll-like receptors. Journal of Biological Chemistry 283 18591-18600
Faisst SR, Faisst F, Grangett C, Schlehofer JR and Rommelaere J (1993) NF-kB upstream regulatory sequences of the HIV-1 LTR are involved in the inhibition of HIV-1 promoter activity by the NS proteins of autonomous parvovirus H-1 and MVMp. Virology 197 770-773
Faith SA, Sweet TJ, Bailey E, Booth T and Docherty JJ (2006) Resveratrol suppresses nuclear factor-kB in herpes simplex virus infected cells.
Antiviral Research in press
Fakhrzadeh L, Laskin JD, Gardner CR and Laskin DL (2003) SOD+/+ Mice are resistant to ozone-induced tissue injury and increases in nitric oxide and TNF-a. American Journal of Respiraotry Cell and Molecular Biology 30 280-287
Fakhrzadeh L, Laskin JD and Laskin DL (2004) Ozone-induced production of nitric oxide and TNF-a and tissue injury are dependent on NF-kB p50. American Journal of Physiology: Lung Cell and Molecular Physiology 287 L279-L285
Fakhrzadeh L, Laskin JD and Laskin DL (2008) Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-alpha following ozone inhalation. Toxicology and Applied Pharmacology in press
Fakioglu E, Wilson SS, Mesquita PM, Hazrati E, Cheshenko N, Blaho JA and Herold BC (2008) Herpes simplex virus down-regulates secretory leukocyte protease inhibitor: a novel immune evasion mechanism. Journal of Virology in press
Fakler CR, Wu B, McMicken HW, Geske RS and Welty SE (2000) Molecular mechanisms of lipopolysaccharide induced ICAM-1 expression in A549 cells. Inflammation Research 49 63-72
Fakruddin JM and Laurence J (2004) Interactions among human immunodeficiency virus (HIV)-1, interferon-gamma and receptor of activated NF-kB ligand (RANKL): implications for HIV pathogenesis. Clinical and Experimental Immunology 137 538-545
Fakruddin JM and Laurence J (2005) HIV-1 Vpr enhances production of receptor of activated NF-kB ligand (RANKL) via potentiation of glucocorticoid receptor activity. Archives of Virology 150 67-78
Falasca L, Farrace MG, Rinaldi A, Tuosto L, Melino G and Piacentini M (2008) Transglutaminase type II is involved in the pathogenesis of endotoxic shock. Journal of Immunology 180 2616-2624
Falcao AS, Fernandes A, Brito MA, Silva RF and Brites D (2006) Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state. Acta Neuropathologica(Berlin) 112 95-105
Falabella P, Varricchio P, Provost B, Espagne E, Ferrarese R, Grimaldi A, de Eguileor M, Fimiani G, Ursini MV, Malva C, Drezen JM and Pennacchio F (2007) Characterization of the IkB-like gene family in polydnaviruses associated with wasps belonging to different Braconid subfamilies. Journal of General Virology 88 92-104
Falchetti R, Fuggetta MP, Lanzilli G, Tricarico M and Ravagnan G (2001) Effects of resveratrol on human immune cell function. Life Sciences 70 81-96
Falk M, Ussat S, Reiling N, Wesch D, Kabelitz D and Adam-Klages S (2004) Caspase inhibition blocks human T cell proliferation by suppressing appropriate regulation of IL-2, CD25, and cell cycle-associated proteins. Journal of Immunology 173 5077-5085
Falschlehner C, Emmerich CH, Gerlach B and Walczak H (2007) TRAIL signalling: Decisions between life and death.International Journal of Biochemistry and Cell Biology in press
Falsig J, Porzgen P, Lotharius J and Leist M (2004) Specific modulation of astrocyte inflammation by inhibition of mixed lineage kinases with CEP-1347. Journal of Immunology 173 2762-2770
Fan C, Li Q, Ross D and Engelhardt JF (2002) Tyrosine phosphorylation of IkBa activates NF-kB through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation. Journal of Biological Chemistry 278 2072-2080
Fan C, Li Q, Zhang Y, Liu X, Luo M, Abbott D, Zhou W and Engelhardt JF (2004) IkBa and IkBb possess injury context-specific functions that uniquely influence hepatic NF-kB induction and inflammation. Journal of Clinical Investigation 113 746-755
Fan C, Zwacka RM and Engelhardt JF (1999) Therapeutic approaches for ischemia/reperfusion injury in the liver. Journal of Molecular Medicine 77 577-592
Fan C-M and Maniatis T (1990) A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence. Genes & Development 4 29-42
Fan C-M and Maniatis T (1991) Generation of p50 subunit of NF-kBby processing of p105 through an ATP-dependent pathway. Nature 354 395-398
Fan DM, Yang M, Jia HR, Gao YD, Wang JH, Ji Q, Xiong DS and Yang CZ (2008) Up-regulation of CD86 and cytokine expression in acute leukemia cells by Ara-C [Article in Chinese]. Xi Bao Yu Fen Zi Mian Xue Za Zhi 24 550-552
Fan F, Wey JS, McCarty MF, Belcheva A, Liu W, Bauer TW, Somcio RJ, Wu Y, Hooper A, Hicklin DJ and Ellis LM (2005) Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells. Oncogene in press
Fan G, Fan Y, Gupta N, Matsuura I, Liu F, Zhou XZ, Lu KP and Gelinas C (2009) Peptidyl-prolyl isomerase Pin1 markedly enhances the oncogenic activity of the Rel proteins in the nuclear factor-kB family. Cancer Research in press
Fan H and Cook JA (2004) Molecular mechanisms of endotoxin tolerance. Journal of Endotoxin Research 10 71-84
Fan H, Sun B, Gu Q, Lafond-Walker A, Cao S and Becker LC (2002) Oxygen radicals trigger activation of NF-kB and AP-1 and upregulation of ICAM-1 in reperfused canine heart. Am J Physiol Heart Circ Physiol 282 H1778-H1786
Fan J, Frey RS and Malik AB (2003) TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. Journal of Clinical Investigation 112 1234-1243
Fan J, Frey RS, Rahman A and Malik AB (2002) Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kB activation and intercellular adhesion molecule-1 expression in endothelial cells. Journal of Biological Chemistry 277 3404-3411
Fan J, Kapus A, Li YH, Rizoli S, Marshall JC and Rotstein OD (2000) Priming for enhanced alveolar fibrin deposition after hemorrhagic shock: role of tumor necrosis factor. American Journal of Respiratory Cell and Molecular Biology 22 412-421
Fan J, Zhang YQ, Li P, Hou M, Tan L, Wang X and Zhu YS (2004) Interaction of plasminogen activator inhibitor-2 and proteasome subunit, Beta type 1 [Article in Chinese]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 36 42-46
Fan JG, Qian Y, Zheng XY, Cai XB and Lu YS (2006) Effects of pentoxifylline on hepatic nuclear factor-kappa B signaling pathway and insulin resistance in nonalcoholic steatohepatitis rats induced by fat-rich diet [Article in Chinese]. Zhonghua Gan Zang Bing Za Zhi 14 762-766
Fan M, Ahmed KM, Coleman MC, Spitz DR and Li JJ (2007) Nuclear factor-kB and manganese superoxide dismutase mediate adaptive radioresistance in low-dose irradiated mouse skin epithelial cells. Cancer Research 67 3220-3228
Fan S, Chen S, Liu Y, Lin Y, Liu H, Guo L, Lin B, Huang S and Xu A (2008) Zebrafish TRIF, a golgi-localized protein, participates in IFN induction and NF-kB activation. Journal of Immunology 180 5373-5383
Fan S, Gao M, Meng Q, Laterra JJ, Symons MH, Coniglio S, Pestell RG, Goldberg ID and Rosen EM (2005) Role of NF-kB signaling in hepatocyte growth factor/scatter factor-mediated cell protection. Oncogene 24 1749-1766
Fan S, Meng Q, Laterra JJ and Rosen EM (2007) Ras effector pathways modulate scatter factor-stimulated NF-kB signaling and protection against DNA damage. Oncogene in press
Fan W, Sui M and Huang Y (2004) Glucocorticoids selectively inhibit Paclitaxel-induced apoptosis: mechanisms and its clinical impact. Current Medicinal Chemistry 11 403-411
Fan W, Yanase T, Morinaga H, Mu YM, Nomura M, Okabe T, Goto K, Harada N and Nawata H (2005) Activation of Peroxisome Proliferator Activated Receptor {gamma} and Retinoid X Receptor inhibits aromatase transcription via NF-kB. Blood 146 85-92
Fan X, Rahnert JA, Murphy TC, Nanes MS, Greenfield EM and Rubin J (2006) Response to mechanical strain in an immortalized pre-osteoblast cell is dependent on ERK1/2. Journal of CellularPhysiology 207 454-460
Fan Y, Dutta J, Gupta N, Fan G and Gelinas C (2008) Regulation of programmed cell death by NF-kB and its role in tumorigenesis and therapy. Advances in Experimental and Medical Biology in press
Fan Y and Gelinas C (2007) An optimal range of transcription potency is necessary for efficient cell transformation by c-Rel to ensure optimal nuclear localization and gene-specific activation. Oncogene 26 4038-4043
Fan Y, Rayet B and Gelinas C (2004) Divergent C-terminal transactivation domains of Rel/NF-kB proteins are critical determinants of their oncogenic potential in lymphocytes. Oncogene 23 1030-1042
Fan YH, Zhao LY, Zheng QS, Dong H, Wang HC and Yang XD (2007) Arginine vasopressin increases iNOS-NO system activity in cardiac fibroblasts through NF-kB activation and its relation with myocardial fibrosis. Life Sciences 81 327-335
Fan YH, Zhao LY, Zheng QS, Xue YS, Yang XD, Tian JW and Xu L (2003) Arginine vasopressin-induced nitric oxide content changes in cultured cardiac fibroblasts and its relation to nuclear factor-kB [Article in Chinese]. Sheng Li Xue Bao 55 417-421
Fan YY, Ly LH, Barhoumi R, McMurray DN and Chapkin RS (2004) Dietary docosahexaenoic acid suppresses T cell protein kinase C{theta} lipid raft recruitment and IL-2 production. Journal of Immunology 173 6151-6160
Fan YY, Son ZM and Dhib-Jalbut S (2001) Mechanism of measles virus failure to activate NF-kB in neuronal cells. Journal of Neurovirology 7 25-34
Fan Z, Bau B, Yang H and Aigner T (2004) IL-1beta induction of IL-6 and LIF in normal articular human chondrocytes involves the ERK, p38 and NFkB signaling pathways. Cytokine 28 17-24
Fan Z, Soder S, Oehler S, Fundel K and Aigner T (2007) Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage. American Journal Pathology in press
Fan Z, Yang H, Bau B, Soder S and Aigner T (2006) Role of mitogen-activated protein kinases and NFkB on IL-1beta-induced effects on collagen type II, MMP-1 and 13 mRNA expression in normal articular human chondrocytes. Rheumatology International 26 900-903
Fang C, Dean J adn Smith JW (2007) A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kB activation in colorectal adenocarcinoma. Cancer Research 679039-9046
Fang CY, Chiang CY, Pan YR, Tse KP, CHang YS and Chang HY (2007) Modulation of Epstein-Barr Virus latent membrane protein 1 activity by intrabodies. Intervirology 50 254-263
Fang H, Jin H and Wang H (2004) Effect of all-trans retinoic acid on airway inflammation in asthmatic rats and its mechanism [Article in Chinese]. J Huazhong Univ Sci Technolog Med Sci 24 229-32
Fang H, Pengal RA, Cao X, Ganesan LP, Wewers MD, Marsh CB and Tridandapani S (2004) Lipopolysaccharide-induced macrophage inflammatory response is regulated by SHIP. Journal of Immunology 173 360-366
Fang IM, Lin CP, Yang CM, Chen MS and Yang CH (2005) Expression of CX3C chemokine, fractalkine, and its receptor CX3CR1 in experimental autoimmune anterior uveitis. Molecular Vision 11 443-451
Fang IM, Yang CH, Lin CP, Yang CM and Chen MS (2005) Effects of pyrrolidine dithiocarbamate, an NF-kB inhibitor, on cytokine expression and ocular inflammation in experimental autoimmune anterior uveitis. J Ocul Pharmacol Ther 21 95-106
Fang IM, Yang CH, Yang CM and Chen MS (2007) Linoleic acid-induced expression of inducible nitric oxide synthase and cyclooxygenase II via p42/44 mitogen-activated protein kinase and nuclear factor-kB pathway in retinal pigment epithelial cells. Experimental Eye Research in press
Fang W, Zhang HX, Wang LY, Qin YW, Wu Y, Wang W and Liu B (2007) Effect of PMTG on atherosclerotic lesion formation and expression of ICAM-1 and VCAM-1 in ApoE-deficient mice [Article in Chinese]. Zhongguo Zhong Yao Za Zhi 32 1320-1323
Fang X, Gao J, Zheng H, Li B, Kong L, Zhang Y, Wang W, Zeng Y and Ye L (2007) The membrane protein of SARS-CoV suppresses NF-kB activation.
Journal of Medical Virology 79 1431-1439
Fang X, Yu S, Bast RC, Liu S, Xu HJ, Hu SX, LaPushin R, Claret FX, Aggarwal BB, Lu Y and Mills GB (2003) Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian caner cells. Journal of Biological Chemistry 279 9653-9661
Fang X, Zhang L, Feng Y, Zhao Y and Dai J (2008) Immunotoxic effects of perfluorononanoic acid on BALB/c mice. Toxicological Sciences in press
Fang YY, Song ZM, Wu T, Raha A, Kalvakolanu DV and Dhib-Jalbut S (2002) Defective NF-kB activation in virus-infected neuronal cells is restored by genetic complementation. Journal of Neurovirology 8 459-463
Fanto N, Gallo G, Cucci A, Semproni M, Vignola D, Quaglia M, Bombardi V, Mastroianni D, Zibella MP, Basile G, Sassano M, Ruggiero V, De Santis R and Carininati P (2008) Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88. Journal of Medicinal Chemistry in press
Faour WH, He QW, Mancini A, Jovanovic D, Antoniou J and Di Battista JA (2006) Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts: role in suppression of c/EBP/NF-kB-mediated MEKK1-induced MMp-1 expression. Journal of Biological Chemistry 281 19849-19860
Faouzi S, Burckhardt BE, Hanson JC, Campe CB, Schrum LW, Rippe RA and Maher JJ (2001) Anti-Fas induces hepatic chemokines and promotes inflammation by an NF-kB-independent, caspase-3-dependent pathway. Journal of Biological Chemistry 276 49077-49082
Farhana L, Dawson MI and Fontana JA (2005) Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kB activation. Cancer Research 65 4909-4917
Farahani M, Treweeke AT, Toh CH, Till KJ, Harris RJ, Cawley JC, Zuzel M and Chen H (2005) Autocrine VEGF mediates the antiapoptotic effect of CD154 on CLL cells. Leukemia 19 524-530
Fardoun RZ, Asghar M, Lokhandwala M (2007) Role of nuclear factor kB (NF-kB) in oxidative stress-induced defective dopamine D1 receptor signaling in the renal proximal tubules of Sprague-Dawley rats. Free Radical Biology and Medicine 42 756-764
Farid M, Reid MB, Li YP, Gerken E and Durham WJ (2005) Effects of dietary curcumin or N-acetylcysteine on NF-kB activity and contractile performance in ambulatory and unloaded murine soleus. Nutr Metab (London) 2 20
Farina AR, Masciulli MP, Tacconelli A, Cappabianca L, De Santis G, Gulino A and Mackay AR (2002) All-trans-retinoic acid induces nuclear factor kB activation and matrix metalloproteinase-9 expression and enhances basement membrane invasivity of differentiation-resistant human SK-N-BE 9N neuroblastoma cells. Cell Growth & Differentiation 13 343-354
Farina AR, Tacconelli A, Vacca A, Maroder M, Gulino A and Mackay AR (1999) Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kB elements. Cell Growth & Differentiation 10 353-367
Farina C, Theil D, Semlinger B, Hohlfeld R and Meinl E (2004) Distinct responses of monocytes to Toll-like receptor ligands and inflammatory cytokines. International Immunology 16 799-809
Farinha P and Gascoyne RD (2005) Molecular pathogenesis of mucosa-associated lymphoid tissue lymphoma. Journal of Clinical Oncology 23 6370-6378
Farivar AS, Mackinnon-Patterson B, Barnes AD and Mulligan MS (2005) The effect of anti-inflammatory properties of Mycophenolate mofetil on the development of lung reperfusion injury. Journal of Heart and Lung Transplantation 24 2235-2242
Farivar AS, Mackinnon-Patterson B, Woolley S, Namkung J, Shimamoto A, Verrier ED and Mulligan MS (2004) FR167653 reduces obliterative airway disease in rats. Journal of Heart and Lung Transplantation 23 985-992
Farivar AS, Woolley SM, Fraga CH, Byrne K and Mulligan MS (2004) Proinflammatory response of alveolar type II pneumocytes to in vitro hypoxia and reoxygenation. American Journal of Transplantation 4 346-351
Farivar AS, Woolley SM, Fraga CH, Thomas R, Salzman AL, Szabo C and Mulligan MS (2004) Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury. Annals of Thoracic Surgery 77 1938-1943
Farivar AS, Woolley SM, Naidu BV, Fraga CH, Byrne K, Thomas R, Salzman AL, Szabo CS and Mulligan MS (2004) Poly (ADP) ribose synthetase inhibition reduces obliterative airway disease in rat tracheal allografts. Journal of Heart and Lung Transplantation 23 993-1002
Farkas S, Herfarth H, Rossle M, Schroeder J, Steinbauer M, Guba M, Beham A, Scholmerich J, Jauch KW and Anthuber M (2001) Quantification of mucosal leucocyte endothelial cell interaction by in vivo fluorescence microscopy in experimental colitis in mice. Clinical and Experimental Immunology 126 250-258
Farley SM, Dotson AD, Purdy DE, Sundholm AJ, Schneider P, Magun BE and Iordanov MS (2006) Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis. Journal of InvestigativeDermatology 126 2438-2451
Farnell MB, He H, Genovese K and Kogut MH (2003) Pharmacological analysis of signal transduction pathways required for oxidative burst in chicken heterophils stimulated by a Toll-like receptor 2 agonist. International Immunopharmacology 3 1677-1684
Farombi EO and Surh YJ (2006) Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. Journal of Biochemistry and Molecular Biology 39 479-491
Farrow B and Evers BM (2002) Inflammation and the development of pancreatic cancer. Surgical Oncology 10 153-169
Farrow B, Sugiyama Y, Chen A, Uffort E, Nealon W and Mark Evers B (2004) Inflammatory mechanisms contributing to pancreatic cancer development. Annals of Surgery 239 763-771
Farver CF, Raychaudhuri B, Buhrow LT, Connors MJ and Thomassen MJ (1998) Constitutive NF-kB levels in human alveolar macrophages from normal volunteers. Cytokine 10 868-871
Fas SC, Baumann S, Zhu JY, Giaisi M, Treiber MK, Mahlknecht U, Krammer PH and Li-Weber M (2006) Wogonin sensitizes resistant malignant cells to TNFa- and TRAIL-induced apoptosis. Blood3700-3706
Fass U, Panickar K, Williams K, Nevels K, Personett D and McKinney M (2004) The role of glutathione in nitric oxide donor toxicity to SN56 cholinergic neuron-like cells. Brain Research 1005 90-100
Fatrai S, Schepers H, Tadema H, Vellenga E, Daenen SM and Schuringa JJ (2008) Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases. Experimental Hematology in press
Faure E (1998) X-ray-induced secretion of cellular factor(s) that enhance(s) HIV-1 promoter transcription in various non-irradiated transfected cell lines. Cell Mol Biol (Noisy-le-grand) 44 1275-1292
Faure E, Equils O, Sieling PA, Thomas L, Zhang FX, Kirschning CJ, Polentarutti N, Muzio M and Arditi M (2000) Bacterial lipopolysaccharide activates NF-kB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. Journal of Biological Chemistry 275 11058-11063
Faure E, Thomas L, Xu H, Medvedev A, Equils O and Arditi M (2001) Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-kB activation. Journal of Immunology 166 2018-2024
Faure P, Ramon O, Favier A and Halimi S (2004) Selenium supplementation decreases nuclear factor-kB activity in peripheral blood mononuclear cells from type 2 diabetic patients. European Journal of Clinical Investigation 34 475-481
Faure V, Courtois V and Goureau O (1998) Tyrosine kinase inhibitors and antioxidants modulate NF-kB and NOS-II induction in retinal epithelial cells. American Journal of Physiology 275 C208-C215
Faurschou A and Gniadecki R (2008) TNF-a stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes. Experimental Dermatology in press
Fausto N, Laird AD and Webber EM (1995) Role of growth factors and cytokines in hepatic regeneration. FASEB Journal 9 1527-1536
Favaudon V and Hennequin C (2005) Targeted drugs in radiation therapy [Article in French]. Cancer Radiotherapy 8 S114-S120
Faveeuw C, Gosset P, Bureau F, Angeli V, Hirai H, Maruyama T, Narumiya S, Capron M and Trottein F (2003) Prostaglandin D2 inhibits the production of interleukin-12 in murine dendritic cells through multiple signaling pathways. European Journal of Immunology 33 889-898
Faye I and Hultmark D (1993) The insect immune proteins and the regulation of their genes. In Parasites and Pathogens of Insects, edited by N Beckage, SN Thompson, BA Federici (Academic Press, San Diego) 2 25-53
Fazal F, Minhajuddin M, Bijli KM, McGrath JL and Rahman A (2007) Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells. Journal of Biological Chemistry 282 3940-3950
Fearon DT (1997) Seeking wisdom in innate immunity. Nature 388 323-324
Fedele G, Frasca L, Palazzo R, Ferrero E, Malavasi F and Ausiello CM (2004) CD38 is expressed on human mature monocyte-derived dendritic cells and is functionally involved in CD83 expression and IL-12 induction. European Journal of Immunology 34 1342-1350
Fedorov SJ, Radchenko OS, Shubina LK, Balaneva NN, Bode AM, Stonik VA and Dong Z (2006) Evaluation of cancer-preventive activity and structure-activity relationships of 3-demethylubiquinone Q(2), isolated from the ascidian Aplidium glabrum, and its synthetic analogs. Pharmaceutical Research 23 70-81
Feeley BT, Park AK, Hoyt EG and Robbins RC (1999) Sulfasalazine inhibits reperfusion injury and prolongs allograft survival in rat cardiac transplants. Journal of Heart and Lung Transplantation 18 1088-1095
Fehr D, Casanova C, Liverman A, Blazkova H, Orth K, Dobbelaere D, Frey J and Burr SE (2006) AopP, a type III effector protein of Aeromonas salmonicida, inhibits the NF-kB signalling pathway.Microbiology 152 2809-2818
Fei F, Yu Y, Schmitt A, Rojewski MT, Chen B, Gotz M, Guillaume P, Dohner H, Bunjes D and Schmitt M (2008) Dasatinib exerts an immunosuppressive effect on CD8(+) T cells specific for viral and leukemia antigens. Experimental Hematology in press
Feig BW, Lu X, Hunt KK, Shan Q, Yu D, Pollock R and Chiao P (1999) Inhibition of the transcription factor nuclear factor-kB by adenoviral-mediated expression of IkBa M results in tumor cell death. Surgery 126 399-405
Feigenbaum L, Fujita K, Collins FS and Jay G (1996) Repression of the NF1 gene by Tax may explain the development of neurofibromas in human T-lymphotropic virus type 1 transgenic mice. Journal of Virology 70 3280-3285
Feinberg J, Fieschi C, Doffinger R, Feinberg M, Leclerc T, Boisson-Dupuis S, Picard C, Bustamante J, Chapgier A, Filipe-Santos O, Ku CL, De Beaucoudrey L, Reichenbach J, Antoni G, Balde R, Alcais A and Casanova JL (2004) Bacillus calmette guerin triggers the IL-12/IFN-gamma axis by an IRAK-4- and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes. European Journal of Immunology 34 3276-3284
Feinberg MW, Watanabe M, Lebedeva MA, Depina AS, Hanai J, Mammoto T, Frederick JP, Wang XF, Sukhatme VP and Jain MK (2004) Transforming growth factor-beta 1 inhibition of vascular smooth muscle cell activation is mediated via Smad3 v. Journal of Biological Chemistry 279 16388-16393
Feinman R, Koury J, Thames M, Barlogie B, Epstein J and Siegel DS (1999) Role of NF-kB in the rescue of multiple myeloma cells from glucocorticoid-induced apoptosis by bcl-2. Blood 93 3044-3052
Feigman R, Siegel DS and Berenson J (2004) Regulation of NF-kB in multiple myeloma: therapeutic implications. Clinical Advances in Hematology and Oncology 2 162-166
Feinstein DL, Brosnan CF, Whitacre CC, Landreth GE, Gavrilyuk V and Heneka MT (2002) PPAR-agonists prevent experimental autoimmune encephalomyelitis. Annals of Neurology 51 694-702
Feinstein DL, Galea E and Reis DJ (1998) Suppression of glial nitric oxide synthase induction by heat shock: effects on proteolytic degradation of IkB-a. Nitric Oxide 1 167-176
Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, Landreth GE, Pershadsingh HA, Weinberg G and Heneka MT (2002) Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Annals of Neurology 51 694-702
Feinstein E and Kimchi A (1995) The death domain: a module shared by proteins with diverse cellular functions. Trends in Biochemical Sciences 20 342-344
Feito-Rodriguez M, Garcia-Macarron J, Ruiz Bravo-Burguillos E, Vera-Casano A and De Lucas-Laguna R (2007) Incontinentia pigmenti: three new cases that demonstrate it is not only a matter of women {Article in Spanish]. Actas Dermosifiliograficas98 112-115
Fekete C, Gereben B, Doleschall M, Harney JW, Miguel Dora J, Bianco AC, Sarkar S, Liposits Z, Rand W, Emerson C, Kacskovics I, Reed Larsen P and Lechan RM (2003) Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonthyroidal illness syndrome. Endocrinology 145 1649-1655
Felberbaum RS (2006) The molecular mechanisms of classic Hodgikin’s lymphoma. Yale Journal of Biological Medicine 78 203-201
Feld M, Galli C, PIccini A and Romano A (2007) Effect on memory of acute administration of naturally secreted fibrils and synthetic amyloid-beta peptides in an invertebrate model.Neurobiology of Learning and Memory in press
Feldman I, Feldman GM, Mobarak C, Dunkelberg JC and Leslie KK (2007) Identification of proteins within the nuclear factor-kB transcriptional complex including estrogen receptor-alpha.American Journal of Obstetrics and Gynecology 196 394.e1-11
Feldmann M, Andreakos E, Smith C, Bondeson J, Yoshimura S, Kiriakidis S, Monaco C, Gasparini C, Sacre S, Lundberg A, Paleolog E, Horwood NJ, Brennan FM and Foxwell BM (2002) Is NF-kB a useful therapeutic target in rheumatoid arthritis? Annals of Rheumatoid Disease 61 II13-II18
Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R, Burgart LJ and Gores GJ (2004) Free fatty acids promote hepatic lipotoxicity by stimulating TNF-a expression via a lysosomal pathway. Hepatology 40 185-194
Felix K, Manna SK, Wise K, Barr J and Ramesh GT (2005) Low levels of arsenite activates nuclear factor-kappaB and activator protein-1 in immortalized mesencephalic cells. Journal of Biochemistry and Molecular Toxicology 19 67-77
Felli MP, Vacca A, Calce A, Bellavia D, Campese AF, Grillo R, Di Giovine M, Checquolo S, Talora C, Palermo R, Di Mario G, Frati L, Gulino A and Screpanti I (2005) PKCtheta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia. Oncogene 24 991-1000
Felty Q and Roy D (2004) Mitochondrial signals to nucleus regulate estrogen-induced cell growth. Medical Hypotheses 64 133-141
Felx M, Guyot MC, Isler M, Turcotte RE, DOyon J, Khatib AM, Leclerc S, Moreau A and Moldovan F (2006) Endothelin-1 (ET-1) promotes MMP-2 and MMP-9 induction involving transcription factor NF-kB in human osteosarcoma.
Clinical Science (London) 110 645-654
Femkin V and Karin M (2007) From death receptor to reactive oxygen species and c-Jun N-terminal protein kinase: the receptor-interacting protein 1 odyssey. Immunology Reviews 220 8-21
Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA and Greene WC (2005) Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. Journal of Immunology 175 6050-6057
Feng B, Cheng S, Hsia CY, King LB, Monroe JG and Liou HC (2005) NF-kB inducible genes BCL-X and cyclin E promote immature B-cell proliferation and survival. Cellular Immunology 232 9-20
Feng B, Cheng S, Pear WS and Liou HC (2004) NF-kB inhibitor blocks B cell development at two checkpoints. Medical Immunology 3 1
Feng C-P, Kulka M and Aurelian L (1993) NF-kB-binding proteins induced by HSV-1 infection of U937 cells are not involved in activation of human immunodeficiency virus. Virology 192 491-500
Feng CS, Ma HC, Yue Y, Zhang YQ and Qu XD (2004) Effect of propofol on the activation of nuclear factor-kB and expression of inflammatory cytokines in cerebral cortex during transient focal cerebral ischemia-reperfusion: experiment with rats [Article in Chinese]. Zhonghua Yi Xue Za Zhi 84 2110-2114
Feng F, Wang L, Albanese N, Holmes A and Xia P (2008) TWEAK attenuates the action of insulin in hepatocytes. Endocrinology in press
Feng G, Liu S, Wang Gl and Liu GJ (2007) Lidocaine attenuates lipopolysaccharide-induced acute lung injury through inhibiting NF-kB activation. Pharmacology 81 32-40
Feng G, Ohmori Y and Chang PL (2005) Production of chemokine CXCL1/KC by okadaic acid through the nuclear factor-kB pathway. Carcinogenesis 27 43-52
Feng GW, Yu LX, Zhang HT and Zhao XG (2004) Transfection of human umbilical vein endothelial cell line ECV-304 with liposome-oligonucleotide complexes under hypothermic and anoxic conditions [Article in Chinese]. Di Yi Jun Yi Da Xue Xue Bao 24 497-500
Feng H, Li XY, Zheng JR, Gao JW, Xu LF and Tang MY (2005) Inhibition of the nuclear factor-kB signaling pathway by leflunomide or triptolide also inhibits the anthralin-induced inflammatory response but does not affect keratinocyte growth inhibition. Biol Pharm Bull 28 1597-1602
Feng H, Xiang H, Mao YW, Wang J, Liu JP, Huang XQ, Liu Y, Liu SJ, Luo C, Zhang XJ, Liu Y and Li DW (2004) Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epithelium-derived growth factor and downstream genes. Oncogene 23 7310-7321
Feng J, Chen BY, Guo MN, Cao J, Zhao HY, LIang DC and Zuo AJ (2007) Changes of nuclear factor-kB and intercellular adhesion molecule-1 in endothelial cells exposed to various intermittent hypoxia [Article in Chinese]. Zhonghua Jie He He Hu Xi Za Zhi30 202-206
Feng J, Li M, Cai T, Tang H and Gu W (2005) Rotavirus-induced murine biliary atresia is mediated by nuclear factor-kappaB. Journal of Pediatric Surgery 40 630-636
Feng JM, Fernandes AO, Campagnoni CW, Hu YH and Campagnoni AT (2004) The golli-myelin basic protein negatively regulates signal transduction in T lymphocytes. Journal of Neuroimmunology 152 57-66
Feng JQ, Xing L, Zhang JH, Zhao M, Horn D, Chan J, Boyce BF, Harris SE, Mundy GR and Chen D (2003) NF-kB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro. Journal of Biological Chemistry 278 29130-29135
Feng P, Scott CW, Cho NH, Nakamura H, Chung YH, Monteiro MJ and Jung JU (2004) Kaposi’s sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like/ubiquitin-associated domain-containing protein to promote protein degradation. Molecular and Cellular Biology 24 3938-3948
Feng R, Anderson G, Xiao G, Elliott G, Leoni L, Mapara MY, Roodman GD and Lentzsch S (2007) SDX-308, a non-steroidal anti-inflammatory agent, inhibits NF-kB activity resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth. Blood 109 2130-2138
Feng R, Lu Y, Bowman LL, Qian Y, Castranova V and Ding M (2005) Inhibition of AP-1, NF-kB and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid. Journal of Biological Chemistry 280 27888-27895
Feng SH and Lo SC (1999) Lipid extract of Mycoplasma penetrans proteinase K-digested lipid-associated membrane proteins rapidly activates NF-kB and activator protein 1. Infection and Immunity 67 2951-2956
Feng SH, Tsai S, Rodriguez J and Lo SC (1999) Mycoplasmal infections prevent apoptosis and induce malignant transformation of interleukin-3-dependent 32D hematopoietic cells. Molecular and Cellular Biology 19 7995-8002
Feng X, Bonni S and Riabowol K (2006) HSP70 induction by ING proteins sensitizes cells to TNF-a receptor mediated apoptosis.Molecular and Cellular Biology 26 9244-9255
Feng X, Gaeta ML, Madge LA, Yang JH, Bradley JR and Pober JS (2001) Caveolin-1 associates with TRAF2 to form a complex that is recruited to TNF receptors. Journal of Biological Chemistry 276 8341-8349
Feng X, Guo Z, Nourbakhsh M, Hauser H, Ganster R, Shao L and Geller DA (2002) Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: the role of NF-kB-repressing factor (NRF) in basal repression of the hiNOS gene. Proceedings of the National Academy of Sciences USA 99 14212-14217
Feng X, Hu Y, DIng J, Ge Y, SOng J, Ai Q, Zhang Z and Xu J (2007) Early treatment with hydroxyethyl starch 130/0.4 causes greater inhibition of pulmonary capillary leakage and inflammatory response than treatment instituted later in sepsis induced by cecal ligation and puncture in rats. Annals ofClinical and Laboratory Science 37 49-56
Feng X, Liu J, Yu M, Zhu S and Xu J (2006) Protective roles of hydroxyethyl starch 130/0.4 in intestinal inflammatory response and survival in rats challenged with polymicrobial sepsis.Clinica Chimica Acta 376 60-67
Feng X, Ren B, Xie W, Huang Z, Liu J, Guan R, Duan M and Xu J (2006) Influence of hydroxyethyl starch 130/0.4 in pulmonary neutrophil recruitment and acute lung injury during polymicrobial sepsis in rats. Acta AnaesthesiologicaScandinavica 50 1081-1088
Feng X, Yan W, Liu X, Duan M, Zhang X and Xu J (2006) Effects of hydroxyethyl starch 130/0.4 on pulmonary capillary leakage and cytokines production and NF-kB activation in CLP-induced sepsis in rats. Journal of Surgical Research 135 129-136
Feng Y and Longmore GD (2005) The LIM protein Ajuba influences interleukin-1-induced NF-kB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex. Molecular and Cellular Biology 25 4010-4022
Feng Y, Wang F, Li X, Wang BY and Wu Q (2005) Involvement of MAPKs and NF-kB pathways in Pseudomonas pyocyanin-induced interleukin-8 expression by human airway epithelial cells [Article in Chinese]. Wei Sheng Wu Xue Bao 45 86-90
Feng Z and Porter AG (1999) NF-kB/Rel proteins are required for neuronal differentiation of SH-SY5Y neuroblastoma cells. Journal of Biological Chemistry 274 30341-30344
Feng ZW, Tan V, Khoo KS and Leck KJ (2003) NF-kB plays a protective role in nitric oxide-induced neuronal apoptosis. Annals of the Academy of Medicine of Singapore 32 S30-S31
Fennewald SM, Aronson JF, Zhang L and Herzog NK (2002) Alterations in NF-kB and RBP-Jk by arenavirus infection of macrophages in vitro and in vivo. Journal of Virology 76 1154-1162
Fenteany G and Schreiber SL (1998) Lactacystin, proteasome function, and cell fate. Journal of Biological Chemistry 273 8545-8548
Fenton JI, Birmignham JM, Hursting SD and Hord NG (2008) Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc(Min/+) colon epithelial cells. International Journal of Cancer in press
Fenton JI, Hord NG, Lavigne JA, Perkins SN and Hursting SD (2005) Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines. Cancer Epidemiol Biomarkers Prev 14 1646-1652
Fenwick C, Na S-Y, Voll RE, Zhong H, Im S-Y, Lee JW and Ghosh S (2000) A subclass of Ras proteins that regulate the degradation of IkB. Science 287 869-873
Ferch U, Meyer zum Buschenfelde C, Gewies A, Wegener E, Rauser S, Peschel C, Krappmann D and Ruland J (2007) MALT1 directs B cell receptor-induced canonical nuclear factor-kB signaling selectively to the c-Rel subunit.
Nature Immunology in press
Ferencz A, Racz B, Gasc B, Benko L, Jancso G, Kurthy M and Roth E (2006) Intestinal ischemic preconditioning in rats and NF-kB activation. Microsurgery 26 54-57
Ferencz A, Szanto Z, Borsiczky B, Kiss K, Kalmar-Nagy K, Szeberenyi J, Horvath PO and Roth E (2002) The effects of preconditioning on the oxidative stress in small-bowel autotransplantation. Surgery 132 877-884
Ferguson AR and Corley RB (2005) Accumulation of marginal zone B cells and accelerated loss of follicular dendritic cells in NF-kB p50-deficient mice. BMC Immunology 6 8
Feriotto G, Finotti A, Volpe P, Treves S, Ferrari S, Angelelli C, Zorzato F and Gambari R (2005) Myocyte enhancer factor 2 activates promoter sequences of the human AbetaH-J-J Locus, Encoding aspartyl-beta-hydroxylase, junctin, and junctate.Molecular and Cellular Biology 25 3261-3275
Ferl GZ, Timmmerman JM and Witte ON (2003) Extending the utility of gene profiling data by bridging microarray platforms. Proceedings of the National Academy of Sciences USA 100 10585-10587
Ferlazzo N, Condello S, Curro M, Parisi G, Ientile R and Caccamo D (2008) NF-kB activation is associated with homocysteine-induced injury in Neuro2a cells. BMC Neuroscience in press
Ferlini C, Scambia G, Marone M, Distefano M, Gaggini C, Ferrandina G, Fattorossi A, Isola G, Benedetti Panici P and Mancuso S (1999) Tamoxifen induces oxidative stress and apoptosis in oestrogen receptor-negative human cancer cell lines. British Journal of Cancer 79 257-263
Ferlito M and De Maio A (2005) Enhanced LPS-induced TNFa production in heat-shocked human promonocytic cells: regulation at the translational/post-translational level. Biochimica et Biophysica Acta 1743 20-28
Ferlito M, Romanenko OG, Ashton S, Squadrito F, Halushka PV and Cook JA (2001) Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production. Journal of Leukocyte Biology 70 821-829
Fernandes A, Falcao AS, Silva RF, Brito MA and Brites D (2007) MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes. European Journal of Neuroscience 25 1058-1068
Fernandes A, Falcao AS, Silva RF, Gordo AC, Gama MJ, Brito MA and Brites D (2006) Inflammatory signalling pathways involved in astroglial activation by unconjugated bilirubin. Journal of Neurochemistry 96 1667-1679
Fernandes A, Vaz AR, Falcao AS, Silva RF, Brito MA and Brites D (2007) Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin.Journal of Neuropathology and Experimental Neurology 66 789-798
Fernandes AF, Guo W, Zhang X, Gallagher M, Ivan M, Taylor A, Pereira P and Shang F (2006) Proteasome-dependent regulation of signal transduction in retinal pigment epithelial cells.Experimental Eye Research 83 1472-1481
Fernandes AF, Zhou J, Zhang X, Bian Q, Sparrow JR, Taylor A, Pereira P and Shang F (2008) Oxidative inactivation of the proteasome in RPE: a potential link between oxidative stress and upregulation of IL-8. Journal of Biological Chemistry in press
Fernandes ES, Passos GF, Campos MM, Araujo JG, Pesquero JL, Avelllar MC, Teixeira MM and Calixto JB (2003) Mechanisms underlying the modulatory action of platelet activating factor (PAF) on the upregulation of kinin B(1) receptors in the rat paw. British Journal of Pharmacology 139 973-981
Fernandes ES, Passos GF, Campos MM, de Souza GE, Fittipaldi JF, Pesquero JL, Teixeira MM and Calixto JB (2005) Cytokines and neutrophils as important mediators of platelet-activating factor-induced kinin B(1) receptor expression. British Journal of Pharmacology 146 209-216
Fernandes G (2008) Progress in nutritional immunology. Immunology Research in press
Fernandes G, Bhattacharya A, Rahman M, Zaman K and Banu J (2008) Effects of n-3 fatty acids on autoimmunity and osteoporosis. Frontiers in Bioscience 13 4015-4020
Fernandes PA, Henriques ES, Pande V, Ramos MJ, Maia ARR, Almeida AAS, Silva BFP, Ribeiro CMS, Ribeiro CFB, Ribeiro DSM, Fonseca DAP, Cunha EMS, Maia FRNC, Pereira JAA, Pacheco JPG, Ferreira JAAD, Matos LRC, Pinto MABP, Borges MCS, Magalhaes PJCR, Teixeira PFRD, Veloso PNBC, Ferreira RJF, Gomes SS, Barros TF, Selao TSJT and Fernandes VMMC (2005) New designs for inhibitors of the NF-kB: DNA binding. Theoretical Chemistry Accounts 113 197-204
Fernandez AM, Fernandez S, Carrero P, Garcia-Garcia M and Torres-Aleman I (2007) Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. Journal of Neuroscience 27 8745-8756
Fernandez de Arriba A, Cavalcanti F, Miralles A, Bayon Y, Alonso A, Merlos M, Garcia-Rafanell J and Forn J (1999) Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid. Molecular Pharmacology 55 753-760
Fernandez MI, Pedron T, Tournebize R, Olivo-Marin JC, Sansonetti PJ and Phalipon A (2003) Anti-inflammatory role for intracellular dimeric immunoglobulin a by neutralization of lipopolysaccharide in epithelial cells. Immunity 18 739-749
Fernandez NQ, Grosshans J, Goltz JS and Stein D (2001) Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation. Development 128 2963-2974
Fernandez P, Guillen MI, Ubeda A, Lopez-Cremades P, Aller E, Lorenzo A, Molina P and Alcaraz MJ (2003) A novel indazolo-triazolo-benzotriazepine exerts anti-inflammatory effects by inhibition of cyclooxygenase-2 activity and nitric oxide synthase-2 expression. Naunyn Schmiedebergs Arch Pharmacol 368 26-32
Fernandez PC and Dobbelaere DA (1999) Ceramide synergizes with phorbol ester or okadaic acid to induce IkB degradation. Biochemical and Biophysical Research Communications 263 63-67
Fernandez PC, Machado J, Jr., Heussler VT, Botteron C, Palmer GH and Dobbelaere DA (1999) The inhibition of NF-kB activation pathways and the induction of apoptosis by dithiocarbamates in T cells are blocked by the glutathione precursor N-acetyl-L-cysteine. Biological Chemistry 380 1383-1394
Fernandez V, Castillo I, Tapia G, Romanque P, Uribe-Echevarria S, Uribe M, Cartier-Ugarte D, Santander G, Vial MT and Videla LA (2006) Thyroid hormone preconditioning: Protection against ischemia-reperfusion liver injury in the rat. Hepatology 45 170-177
Fernandez V, Tapia G, Varela P and Videla LA (2005) Redox regulation of thyroid hormone-induced Kupffer cell-dependent IkB-a phosphorylation in relation to inducible nitric oxide synthase expression. Free Radical Research 39 411-418
Fernandez V, Tapia G, Varela P, Castillo I, Mora C, Moya F, Orellana M and Videla LA (2005) Redox up-regulated expression of rat liver manganese superoxide dismutase and Bcl-2 by thyroid hormone is associated with inhibitor of kB-a phosphorylation and nuclear factor-kB activation. Journal of Endocrinology 186 539-547
Fernandez V, Tapia G, Varela P, Gaete L, Vera G, Mora C, Vial MT and Videla LA (2008) Causal role of oxidative stress in liver preconditioning by thyroid hormone in rats. Free Radical Biology and Medicine in press
Fernandez V, Tapia G, Varela P, Romanque P, Cartier-Ugarte D and Videla LA (2005) Thyroid hormone-induced oxidative stress in rodents and humans: A comparative view and relation to redox regulation of gene expression. Comparative Biochemistry and Physiology: Toxicology & Pharmacology in press
Fernandez Y, Verhaegen M, Miller TP, Rush JL, Steiner P, Opipari AW Jr, Lowe SW and Soengas MS (2005) Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications. Cancer Research 65 6294-6304
Fernandez-Calotti P, Gamberale R, Costas M, Sanchez Avalos J, Geffner J and Giordano M (2006) Fludarabine induces pro-inflammatory activation of human monocytic cells through a MAPK/ERK pathway. International Immunopharmacology 6 715-723
Fernandez-Figueras MT, Puig L, Musulen E, Gilaberte M, Lerma E, Serrano S, Ferrandiz C and Ariza A (2006) Expression profiles associated with aggressive behavior in Merkel cell carcinoma.Modern Pathology 20 90-101
Fernandez-Lizarbe S, Pascual M, Gascon MS, Blanco A and Guerri C (2007) Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages. Molecular Immunology in press
Fernandez-Majada V, Aguilera C, Villanueva A, Vilardell F, Robert-Moreno A, Aytes A, Real FX, Capella G, Mayo MW, Espinosa L and Bigas A (2007) Nuclear IKK activity leads to dysregulated Notch-dependent gene expression in colorectal cancer.Proceedings of the National Academy of Sciences USA 104 276-281
Fernandez-Martinez A, Callejas NA, Casado M, Bosca L and Martin-Sanz P (2004) Thioacetamide-induced liver regeneration involves the expression of cyclooxygenase 2 and nitric oxide synthase 2 in hepatocytes. Journal of Hepatology 40 963-970
Fernandez-Martinez AB, Collado B, Bajo AM, Sanchez-Chapado M, Prieto JC and Carmena MJ (2007) Vasoactive intestinal peptide induces cyclooxygenase-2 expression through nuclear factor-kB in human prostate cell lines Differential time-dependent responses in cancer progression. Molecular and Cellular Endocrinology 270 8-16
Fernandez-Zapico ME, Gonzalez-Paz NC, Weiss E, Savoy DN, Molina JR, Fonseca R, Smyrk TC, Chari ST, Urrutia R and Billadeau DD (2005) Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis. Cancer Cell 7 39-49
Ferrandiz ML, Maicas N, Garcia-Arnandis I, Terencio MC, Motterlini R, Devesa I, Joosten LA, van den Berg WB and Alcaraz MJ (2007) Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis. Annals of Rhematoid Diseases in press
Fernyhough P, Smith DR, Schapansky J, Van Der Ploeg R, Gardiner NJ, Tweed CW, Kontos A, Freeman L, Purves-Tyson TD and Glazner GW (2005) Activation of nuclear factor-kB via endogenous tumor necrosis factor alpha regulates survival of axotomized adult sensory neurons. Journal of Neuroscience 25 1682-1690
Ferrada MA, Gordon EL, Jen KY, He HZ, Lu X, Barone LM, Amirifeli S, Perkins DL and Finn PW (2008) HIF-1a regulates epithelial inflammation by cell autonomous NFkB activation and paracrine stromal remodeling. Respriation Research in press
Ferrandon D, Imler JL and Hoffmann JA (2004) Sensing infection in Drosophila: Toll and beyond. Seminars in Immunology 16 43-53
Ferrandon D, Imler JL, Hetru C and Hoffmann JA (2007) The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections. Nature ReviewsImmunology in press
Ferrante A, Robinson BS, Singh H, Jersmann HP, Ferrante JV, Huang ZH, Trout NA, Pitt MJ, Rathjen DA, Easton CJ, Poulos A, Prager RH, Lee FS and Hii CS (20060 A novel beta-oxa polyunsaturated fatty acid downregulates the activation of the IkB kinase/nuclear factor kB pathway, inhibits expression of endothelial cell adhesion molecules, and depresses inflammation.Circulation Research 99 34-41
Ferreira AM, Ferrari M, Trostchansky A, Batthyány C, Souza JM, Alvarez MN, López GV, Baker PR, Schopfer FJ, O’Donnell V, Freeman BA, Rubbo H (2008) Macrophage activation induces formation of the anti-inflammatory lipid cholesteryl-nitrolinoleate. Biochemical Journal in press
Ferreira CV, Bos CL, Versteeg HH, Justo GZ, Duran N and Peppelenbosch MP (2004) Molecular mechanism of violacein-mediated human leukemia cell death. Blood 104 1459-1464
Ferreira V, Sidenius N, Tarantino N, Hubert P, Chatenoud L, Blasi F and Korner M (1999) In vivo inhibition of NF-kB in T-lineage cells leads to a dramatic decrease in cell proliferation and cytokine production and to increased cell apoptosis in response to mitogenic stimuli, but not to abnormal thymopoiesis. Journal of Immunology 162 6442-6450
Ferreira V, Tarantino N and Korner M (1998) Discrimination between RelA and RelB transcriptional regulation by a dominant negative mutant of IkBa. Journal of Biological Chemistry 273 592-599
Ferreira V, van Dijk KW, Groen AK, Vos RM, van der Kaa J, Gijbels MJ, Havekes LM and Pannekoek H (2006) Macrophage-specific inhibition of NF-kB activation reduces foam-cell formation. Atherosclerosis 192 283-290
Ferreiro DU, Cervantes CF, Truhlar SM, Cho SS, Wolynes PG and Komives EA (2007) Stabilizing IkBa by “consensus” design.Journal of Molecular Biology 365 1201-1216
Ferrer I, Marti E, Lopez E and Tortosa A (1998) NF-kB immunoreactivity is observed in association with b A4 diffuse plaques in patients with Alzheimer’s Disease. Neuropathology and Applied Neurobiology 24 271-277
Ferrero RL, Ave P, Ndiaye D, Bambou JC, Huerre MR, Philpott DJ and Memet S (2007) NF-kB activation during acute Helicobacter pylori infection in mice. Infection and Immunity in press
Ferrero-Miliani L, Nielsen OH, Andersen PS and Girardin SE (2007) Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1beta generation. Clinical and Experimental Immunology 147 227-235
Ferri N, Garton KJ and Raines EW (2003) An NF-kB-dependent transcriptional program is required for collagen remodeling by human smooth muscle cells. Journal of Biological Chemistry 278 19757-19764
Ferrier R, Nougarede R, Doucet S, Kahn-Perles B, Imbert J and Mathieu-Mahul D (1999) Physical interaction of the bHLH LYL1 protein and NF-kB1 p105. Oncogene 18 995-1005
Ferrigno P and Silver PA (1999) Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival. Oncogene 18 6129-6134
Ferris RL and Grandis JR (2007) NF-kB gene signatures and p53 mutations in head and neck squamous cell carcinoma. ClinicalCancer Research 13 5663-5664
Ferry S, Matsuda M, Yoshida H and Hirata M (2002) Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkB-mediated cell survival pathway. Carcinogenesis 23 2031-2041
Fessele S, Boehlk S, Mojaat A, Miyamoto NG, Werner T, Nelson EL, Schlondorff D and Nelson PJ (2001) Molecular and in silico characterization of a promoter module and C/EBP element that mediate LPS-induced RANTES/CCL5 expression in monocytic cells. FASEB Journal 15 577-579
Fessler MB, Arndt PG, Just Ik, Nick JA, Malcolm KC and WOrthen GS (2007) A dual role for RhoA in suppression and induction of cytokines in the human neutrophil. Blood 109 1248-1256
Fessler SP, Chin YR and Horwitz MS (2004) Inhibition of tumor necrosis factor (TNF) signal transduction by the adenovirus group C RID complex involves downregulation of surface levels of TNF receptor 1. Journal of Virology 78 13113-13121
Fessler SP, Delgado-Lopez F and Horwitz MS (2004) Mechanisms of E3 modulation of immune and inflammatory responses. Current Topics in Microbiology and Immunology 273 113-135
Festjens N, Vanden Berghe T, Cornelis S and Vandenabeele P (2007) RIP1, a kinase on the crossroads of a cell’s decision to live or die.Cell Death and Differentiation 14 400-410
Feuerhake F, Kutok JL, Monti S, Chen W, LaCasce AS, Cattoretti G, Kurtin P, Pinkus GS, de Leveal L, Harris NL, Savage KJ, Neuberg D, Habermann TM, Dalla-Favera R, Golub TR, Aster JC and Shipp MA (2005) NFkB activity, function and target gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes. Blood 106 1392-1399
Feuillard J, Dargemont C, Ferreira V, Tarantino N, Debre P, Raphael M and Korner M (1997) Nuclear Rel-A and c-Rel protein complexes are differentially distributed within human thymocytes. Journal of Immunology 158 2585-2591
Feuillard J, Gouy H, Bismuth G, Lee LM, Débré P and Körner M (1991) NF-kB activation by tumor necrosis factor a in the Jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca2+-regulated kinases. Cytokine 3 257-265
Feuillard J, Korner M, Fourcade C, Costa A, Binet JL, Debre P and Raphael M (1994) Visualization of the endogenous NF-kB p50 subunit in the nucleus of follicular dendritic cells in germinal centers. Journal of Immunology 152 12-21
Feuillard J, Körner M, Israël A, Vassy J and Raphael M (1996) Differential nuclear localization of p50, p52 and RelB proteins in human accessory cells of the immune repsonse in situ. European Journal of Immunology 26 2547-2551
Feuillard J, Memet S, Goudeau B, Lilienbaum A, Schmidt-Ullrich R, Raphael M and Israel A (2000) In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kB/Rel complexes. International Immunology 12 613-621
Feuillard J, Schuhmacher M, Kohanna S, Asso-Bonnet M, Ledeur F, Joubert-Caron R, Bissieres P, Polack A, Bornkamm GW and Raphael M (2000) Inducible loss of NF-kB activity is associated with apoptosis and Bcl-2 down-regulation in Epstein-Barr virus-transformed B lymphocytes. Blood 95 2068-2075
Fialkow L, Wang Y and Downey GP (2007) Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radical Biology and Medicine 42 153-164
Fichorova RN, Tucker LD and Anderson DJ (2001) The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission. Journal of Infectious Diseases 184 418-428
Fichorova RN, Zhou F, Ratnam V, Atanassova V, Jiang S, Strick N and Neurath AR (2005) Anti-human immunodeficiency virus type 1 microbicide cellulose acetate 1,2-benzenedicarboxylate in a human in vitro model of vaginal inflammation. Antimicrob Agents Chemother 49 323-335
Fichtner-Feigl S, Fuss IJ, Preiss JC, Strober W and Kitani A (2005) Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kB decoy oligonucleotides. Journal of Clinical Investigation 115 3057-3071
Fidan H, Sahin O, Yavuz Y, Kilbas A, Cetinkaya Z, Ela Y, Ozen OA and Altuntas I (2007) Caffeic acid phenethyl ester reduces mortality and sepsis-induced lung injury in rats. Critical Care Medicine 35 2822-2829
Fieber C, Baumann P, Vallon R, Termeer C, Simon JC, Hofmann M, Angel P, Herrlich P and Sleeman JP (2004) Hyaluronan-oligosaccharide-induced transcription of metalloproteases. Journal of Cell Science 117 359-367
Fiebeler A, Schmidt F, Muller DN, Park JK, Dechend R, Bieringer M, Shagdarsuren E, Breu V, Haller H and Luft FC (2001) Mineralocorticoid receptor affects AP-1 and nuclear factor-kB activation in angiotensin II-induced cardiac injury. Hypertension 37 787-793
Fiebich BL, Grozdeva M, Hess S, Hull M, Danesch U, Bodensieck A, Bauer R Fiebich BL, Grozdeva M, Hess S, Hull M, Danesch U, Bodensieck A and Bauer R (2005) Title? Planta Med 71 12-19
Fiebich BL, Hofer TJ, Lieb K, Huell M, Butcher RD, Schumann G, Schulze-Osthoff K and Bauer J (1999) The non-steroidal anti-inflammatory drug tepoxalin inhibits interleukin-6 and alpha1-anti-chymotrypsin synthesis in astrocytes by preventing degradation of IkB-a. Neuropharmacology 38 1325-1333
Fiebich BL, Lieb K, Engels S and Heinrich M (2002) Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells. Journal of Neuroimmunology 1332 18-24
Fiebich BL, Schleicher S, Butcher RD, Craig A and Lieb K (2000) The neuropeptide substance P activates p38 mitogen-activated protein kinase resulting in IL-6 expression independently from NF-kB. Journal of Immunology 165 5606-5611
Fiebeler A and Luft FC (2005) The mineralocorticoid receptor and oxidative stress. Heart Failure Reviews 10 47-52
Fiedler MA and Wernke-Dollries K (1999) Incomplete regulation of NF-kB by IkBa during respiratory syncytial virus infection in A549 cells. Journal of Virology 73 4502-4507
Fiedler MA, Wernke-Dollries K and Stark JM (1996) Inhibition of viral replication reverses respriatory syncytial virus-induced NF-kB activation and interleukin-8 gene expression in A549 cells. Journal of Virology 70 9079-9082
Fiedler MA, Wernke-Dollries K and Stark JM (1996) Mechanism of RSV-induced IL-8 gene expression in A549 cells before viral replication. Am J Physiol 271 L963-L971
Fiedler MA, Wernke-Dollries K and Stark JM (1998) Inhibition of TNF-a-induced NF-kB activation and IL-8 release in A549 cells with the proteasome inhibitor MG-132. American Journal of Respiration and Cell and Molecular Biology 19 259-268
Field N, Low W, Daniels M, Howell S, Daviet L, Boshoff C and Collins M (2003) KSHV vFLIP binds to IKK-g to activate IKK. Journal of Cell Science 116 3721-3728
Fields ER, Seufzer BJ, Oltz EM and Miyamoto S (2000) A switch in distinct I kappa B alpha degradation mechanisms mediates constitutive NF-kB activation in mature B cells. Journal of Immunology 164 4762-4767
Fietta AM, Morosini M, Meloni F, Bianco AM and Pozzi E (2002) Pharmacological analysis of signal transduction pathways required for mycobacterium tuberculosis-induced IL-8 and MCP-1 production in human peripheral monocytes. Cytokine 19 242-249
Figarola JL, Loera S, Weng Y, Shanmugam N, Natarajan R and Rabbar S (2008) LR-90 prevents dyslipidaemia and diabetic nephropathy in the Zucker diabetic fatty rat. Dibetolgia in press
Figarola JL, Shanmugam N, Natarajan R, and Rahbar S (2007) Anti-inflammatory effects of the advanced glycation end product inhibitor LR-90 in human monocytes. Diabetes 56 647-655
Figueroa YG, Chan AK, Ibrahim R, Tang Y, Burow ME, Alam J, Scandurro AB and Beckman BS (2002) NF-kB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression. Experimental Hematology 30 1419-1427
Filep JG, Khreiss T and Jozsef L (2005) Lipoxins and aspirin-triggered lipoxins in neutrophil adhesion and signal transduction. Prostaglandins Leukotrines and Essential Fatty Acids 73 257-262
Filipe-Santos O, Bustamante J, Haverkamp MH, Vinolo E, Ku C-L, Puel A, Frucht DM, Christel K, von Bernuth H, Jouanguy E, Feinberg J, Durandy A, Senechal B, Chapgier A, Vogt G, de Beaucoudrey L, Fieschi C, Capucine P, Garfa M, Chemli J, Bejaoui M, Tsolia MN, Kutukculer N, Plebani A, Notarangelo L, Bodemer C, Geissmann F, Israel A, Veron M, Knackstedt M, Barbouche R, Abel L, Magdorf K, Gendrel D, Agou F, Holland SM, and Casanova J-L (2006) X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. Journal of Experimental Medicine in press
Fillet M, Bentires-Alj M, Deregowski V, Greimers R, Gielen J, Piette J, Bours V and Merville MP (2003) Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity. Biochemical Pharmacology 65 1633-1642
Filleur F, Pouget C, Allais DP, Kaouadji M and Chulia AJ (2002) Lignans and neolignans from Myristica argentea Warb. Natural Products Letters 16 1-7
Fillmann H, Kretzmann NA, San-Miguel B, Llesuy S, Marroni N, Gonzalez-Gallego J and Tunon MJ (2007) Glutamine inhibits over-expression of pro-inflammatory genes and down-regulates the nuclear factor kB pathway in an experimental model of colitis in the rat. Toxicology in press
Filomeni G, Aquilano K, Rotilio G and Ciriolo MR (2005) Antiapoptotic response to induced GSH depletion: involvement of heat shock proteins and NF-kB activation. Antioxidants and Redox Signaling 7 446-455
Filomeni G, Rotilio G and Ciriolo M (2002) Cell signalling and the glutathione redox system. Biochem Pharmacol 64 1057
Filosto M, Tonin P, Vattemi G, Savio C, Rizzuto N and Tomelleri G (2003) Transcription factors c-Jun/activator protein-1 and nuclear factor-kB in oxidative stress response in mitochondrial diseases. Neuropathology and Applied Neurobiology 29 52-59
Finco TS and Baldwin AS (1995) Mechanistic aspects of NF-kB regulation: the emerging role of phosphorylation and proteolysis. Immunity 3 263-272
Finco TS and Baldwin Jr AS (1993) kB site-dependent induction of gene expression by diverse inducers of nuclear factor kB requires Raf-1. Journal of Biological Chemistry 268 17676-17679
Finco TS, Beg AA and Baldwin Jr AS (1994) Inducible phosphorylation ofIkBa is not sufficient for its dissociation from NF-kB and is inhibited by protease inhibitors. Proceedings of the National Academy of Sciences USA 91 11884-11888
Finco TS, Westwick JK, Norris JL, Beg AA, Der CJ and Baldwin Jr AS (1997) Oncogenic Ha-Ras-induced signaling activates NF-kB transcriptional activity, which is required for cellular transformation. Journal of Biological Chemistry 272 24113-24116
Findlay DM and Haynes DR (2005) Mechanisms of bone loss in rheumatoid arthritis. Modern Rheumatology 15 232-240
Fine SM, Maggirwar SB, Elliott PR, Epstein LG, Gelbard HA and Dewhurst S (1999) Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia. Journal of Neuroimmunology 95 55-64
Fink J, Gu F, Ling L, Tolfvenstam T, Olfat F, Chin KC, Aw P, George J, Kuznetsov VA, Schreiber M, Vaudevan SG and Hibbered ML (2007) Host gene expression profiling of dengue virus infection in cell lines and patients. PLoS Neglected Tropical Diseases 1 e86
Fink J, Steer JH, Joyce DA, McWilliam AS and Stewart GA (2003) Pro-inflammatory effects of Burkholderia cepacia on cystic fibrosis respiratory epithelium. FEMS Immunol Med Microbiol 38 273-282
Fink K, Duval A, Martel A, Soucy-Faulkner A and Grandvaux N (2008) Dual role of NOX2 in respiratory syncytial virus- and Sendai virus-induced activation of NF-kB in airway epithelial cells. Journal of Immunology 180 6911-6922
Fink MP (2003) Nuclear factor-kB: is it a therapeutic target for the adjuvant treatment of sepsis? Critical Care Medicine 31 2400-2402
Fink MP (2004) Ethyl pyruvate: a novel treatment for sepsis and shock. Minerva Anestesiol 70 365-371
Fink MP (2007) Ethyl pyruvate: a novel treatment for sepsis.Novartis Foundation Symposium 280 147-156
Fink MP (2007) Ethyl pyruvate: a novel treatment for sepsis.Current Drug Targets 8 515-518
Finley D (2001) Signal transduction. An alternative to destruction. Nature 412 283-286
Finn PW, He H, Ma C, Mueller T, Stone JR, Liou HC, Boothby MR and Perkins DL (2002) Molecular profiling of the role of the NF-kB family of transcription factors during alloimmunity. Journal of Leukocyte Biology 72 1054-1062
Finn PW, Stone JR, Boothby MR and Perkins DL (2001) Inhibition of NF-kB-dependent T cell activation abrogates acute allograft rejection. Journal of Immunology 167 5994-6001
Finnberg N and El-Deiry WS (2004) Activating FOXO3a, NF-kB and p53 by targeting IKKs: an effective multi-faceted targeting of the tumor-cell phenotype? Cancer Biology Therapy 3 614-616
Finnberg N, Klein-Szanto AJ and El-Deiry WS (2007) TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. Journal of Clinical Investigation in press
Fionda C, Nappi F, Piccoli M Frati L, Santoni A and Cippitelli M (2007) 15-deoxy-d12,14-prostaglandin J2 negatively regulates RANKL gene expression in activated T lymphocytes: role of NF-kB and early growth response transcription factors. Journal ofImmunology 178 4039-4050
Fiorentini C, Falzano L, Travaglione S and Fabbri A (2003) Hijacking Rho GTPases by protein toxins and apoptosis: molecular strategies of pathogenic bacteria. Cell Death & Differentiation 10 147-152
Fiorentino L, Stehlik C, Oliveira V, Ariza ME, Godzik A and Reed JC (2002) A novel PAAD-containing protein that modulates NF-kB induction by cytokines TNFa and IL1beta. Journal of Biological Chemistry 277 35333-35340
Fiorillo C, Becatti M, Pensalfini A, Cecchi C, Lanzilao L, Donzelli G, Nassi N, Giannini L, Borchi E and Nassi P (2008) Curcumin protects cardiac cells against ischemia-reperfusion injury: effects on oxidative stress, NF-kB, and JNK pathways. Free Radical Biology and Medicine in press
Fiorini E, Schmitz I, Mariessen WE, Osborn SL, Touma M, Sasada T, Reche PA, Tibaldi EV, Hussey RE, Kruisbeek AM, Reinherz EL and Clayton LK (2002) Peptide-induced negative selection of thymocytes activates transcription of an NF-kB inhibitor. Molecular Cell 9 637-648
Fiorucci G, Olivetta E, Chiantore MV and Federico M (2007) Microarray analysis reveals CCL24/eotaxin-2 as an effector of the pathogenetic effects induced by HIV-1 Nef. Current Drug Discovery Technologies 4 12-23
Fiorucci S and Del Soldato P (2003) NO-aspirin: mechanism of action and gastrointestinal safety. Dig Liver Dis 35 S9-S19
Fiorucci S, Distrutti E, Mencarelli A, Rizzo G, Di Lorenzo AR, Baldoni M, Del Soldato P, Morelli A and Wallace J (2004) Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates anti-adhesive properties of NCX-4016 (NO-aspirin) on neutrophil-endothelial cell adherence. J Pharmacol Exp Ther 309 1174-1182
Firestein GS (2004) NF-kB: Holy Grail for rheumatoid arthritis? Arthritis and Rheumatism 50 2381-2386
Firestein GS and Manning AM (1999) Signal transduction and transcription factors in rheumatic disease. Arthritis and Rheumatism 42 609-621
Fischer C, Page S, Weber M, Eisele T, Neumeier D and Brand K (1999) Differential effects of lipopolysaccharide and tumor necrosis factor on monocytic IkB kinase signalsome activation and IkB proteolysis. Journal of Biological Chemistry 274 24625-24632
Fischer D, Bhattacharya R, Osburg B and Bickel U (2005) Inhibition of monocyte adhesion on brain-derived endothelial cells by NF-kB decoy/polyethylenimine complexes. Journal of Gene Medicine 7 1063-1076
Fischer JG, Glauert HP, Yin T, Sweeney-Reeves ML, Larmonier N and Black MC (2002) Moderate iron overload enhances lipid peroxidation in livers of rats, but does not affect NF-kB activation induced by the peroxisome proliferator, wy-14,643. Journal of Nutrition 132 2525-2531
Fischer KD, Tedford K and Wirth T (2004) New roles for Bcl10 in B-cell development and LPS response. Trends in Immunology 25 113-116
Fischer N, Kopper B, Graf N, Schlehofer JR, Grasser FA and Mueller-Lantzsch N (1999) Functional analysis of different LMP1 proteins isolated from Epstein-Barr virus-positive carriers. Virus Research 60 41-54
Fischer WH, Jagels MA and Hugli TE (1999) Regulation of IL-6 synthesis in human peripheral blood mononuclear cells by C3a and C3a(desArg). Journal of Immunology 162 453-459
Fiset PO, Tulic MK, Skrablim PS, Grover SM, Letuve S, Mazer BD and Hamid Q (2006) Signal transducer and activator of transcription 6 down-regulates toll-like receptor-4 expression of a monocytic cell line. Clinical and Experimental Allergy 36 158-165
Fisette PL, Ram S, Andersen JM, Guo W and Ingalls RR (2003) The lip lipoprotein from Neisseria gonorrhoeae stimulates cytokine release and NF-kB activation in epithelial cells in a TLR2-dependent manner. Journal of Biological Chemistry 278 46252-46260
Fisher C (2000) IKKa-/- mice share phenotype with pupoid fetus (pf/pf) and repeated eplation (Er/Er) mutant mice. Trends in Genetics 16 482-484
Fisher JL, Thomas-Mudge RJ, Elliott J, Hards Dk, Sims NA, Slavin J, Martin TJ and Gillespie MT (2006) Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically. Cancer Research 66 3620-3628
Fisher L, Soomets U, Cortes Toro V, Chilton L, Jiang Y, Langel U and Iverfeldt K (2004) Cellular delivery of a double-stranded oligonucleotide NFkB decoy by hybridization to complementary PNA linked to a cell-penetrating peptide. Gene Therapy 11 1264-1272
Fisher WG, Yang PC, Medikonduri RK and Jafri MS (2006) NFAT and NFkB activation in T lymphocytes: a model of differential activation of gene expression. Annals of Biomedical Engineering in press
Fishman P, Bar-Yehuda S, Ardon E, Rath-Wolfson L, Barrer F, Ochaion A and Madi L (2003) Targeting the A3 adenosine receptor for cancer therapy: inhibition of prostate carcinoma cell growth by A3AR agonist. Anticancer Research 23 2077-2083
Fishman P, Bar-Yehuda S, Madi L, Rath-Wolfson L, Ochaion A, Cohen S and Baharav E (2006) The PI3K-NF-kB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis. Arthritis Research andTherapy 8 R33
Fishman P, Bar-Yehuda S, Ohana G, Barer F, Ochaion A, Erlanger A and Madi L (2004) An agonist to the A(3) adenosine receptor inhibits colon carcinoma growth in mice via modulation of GSK-3beta and NF-kB. Oncogene 23 2465-2471
Fiskerstrand CF, Newey P, Millan F, Quinn JP (1997) The role of the octamer binding proteins and the NF-kB complex in neuropeptide gene expression. Biochemical Society Transactions 25 S573
Fisslthaler B, Benzing T, Busse R and Fleming I (2003) Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. Nitric Oxide 8 253-261
Fitau J, Bouday G, Coulon F, Quillard T and Charreau B (2006) The adaptor molecule LNK negatively regulates TNFa-dependent VCAM-1 expressin in endothelial cells through inhibition of the ERK1 and 2 pathways. Journal of Biological Chemistry 281 20148-10159
Fister S, Schlotawa L, Gunthert AR, Emons G and Grundker C (2007) Increase of doxorubicin-induced apoptosis after knock-down of gonadotropin-releasing hormone receptor expression in human endometrial, ovarian and breast cancer cells.Gynecological Endocrinology in press
Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE and Baird AW (2007) Tumour necrosis factor-a (TNF-a) increases nuclear factor kB (NFkB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells. VeterinaryImmunology and Immunopathology in press
Fitzgerald KA, Bowie AG, Skeffington BS and O’Neill LA (2000) Ras, protein kinase C zeta, and IkB kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kB by hyaluronic acid fragments in T-24 carcinoma cells. Journal of Immunology 164 2053-2063
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM and Maniatis T (2003) IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nature Immunology 4 491-496
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA and O’Neill LA (2001) Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 413 78-83
Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT (2003) LPS-TLR4 signaling to IRF-3/7 and NF-kB involves the Toll adapters TRAM and TRIF. Journal of Experimental Medicine 198 1043-1055
Fitzgerald M, Webber E, Donovan J and Fausto N (1995) Rapid DNA binding by nuclear factor kB in hepatocytes at the start of liver regeneration. Cell Growth & Differentiation 6 417-427
Fitzgerald SM, Chi DS, Hall HK, Reynolds SA, Aramide O, Lee SA and Krishnaswamy G (2003) GM-CSF induction in human lung fibroblasts by IL-1beta, TNF-a, and macrophage contact. Journal of Interferon and Cytokine Research 23 57-65
Fitzgerald SM, Chi DS, Lee SA, Hall K and Krishnaswamy G (2004) Inhibition of GM-CSF production in fibroblast-monocyte coculture by prednisone and effects of RHGM-CSF on human lung fibroblasts. Frontiers in Bioscience 9 342-348
Fitzgerald SM, Lee SA, Hall HK, Chi DS, Krishnaswamy G (2003) Human lung fibroblasts express IL-6 in response to signaling following mast cell contact. American Journal of Respiratory Cell and Molecular Biology 30 585-593
Fitzner B, Sparmann G, Emmrich J, Liebe S and Jaster R (2004) Involvement of AP-1 proteins in pancreatic stellate cell activation in vitro. International Journal of Colorectal Disease 19 414-420
Fitzpatrick LR, Hertzog KL, Quatse AL, Koltun WA, Small JS and Vrana K (2007) Effects of the probiotic formulation VSL#3 on colitis in weanling rats. Journal of Pediatric Gastroenterology and Nutrition 44 561-570
Fitzpatrick LR, Small J, Hoerr RA, Bostwick EF, Maines L and Koltun WA (2008) In vitro and in vivo effects of the probiotic Escherichia coli strain M-17: immunomodulation and attenuation of murine colitis. British Journal of Nutrition in press
Fitzpatrick LR, Wang J and Le T (2001) Caffeic acid phenethyl ester, an inhibitor of nuclear factor-kB, attenuates bacterial peptidoglycan polysaccharide-induced colitis in rats. J Pharmacol Exp Ther 299 915-920
Fitzpatrick LR, Wang J and Le T (2002) Gliotoxin, an inhibitor of nuclear factor-kB, attenuates peptidoglycan-polysaccharide-induced colitis in rats. Inflammatory Bowel Disease 8 159-167
Fitzpatrick LR, Wang J, Le T and Calingasan N (2003) Time course of colonic nuclear factor-kB expression during bacterial peptidoglycan-polysaccharide-induced colitis in rats. Dig Dis Sci 48 775-782
Fiumara P, Snell V, Li Y, Mukhopadhyay A, Younes M, Gillenwater AM, Cabanillas F, Aggarwal BB and Younes A (2001) Functional expression of receptor activator of nuclear factor kB in Hodgkin disease cell lines. Blood 98 2784-2790
Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, Shelhamer JH and Suffredini AF (2002) Inflammatory promoting activity of HMGB1 on human microvascular endothelial cells. Blood 101 2652-2660
Flaherty DM, Monick MM, Carter AB, Peterson MW and Hunninghake GW (2002) Oxidant-mediated increases in redox factor-1 nuclear protein and activator protein-1 DNA binding in asbestos-treated macrophages. Journal of Immunology 168 5675-5681
Flanagan AM, Massey HM, Wilson C, Vellodi A, Horton MA and Steward CG (2002) Macrophage colony-stimulating factor and receptor activator NF-kB ligand fail to rescue osteoclast-poor human malignant infantile osteopetrosis in vitro. Bone 30 85-90
Flati V, Pastore LI, Griffioen AW, Satijn S, Toniato E, D’Alimonte I, Laglia E, Marchetti P, Gulino A and Martinotti S (2006) Endothelial cell anergy is mediated by bFGF through the sustained activation of p38-MAPK and NF-kB inhibition.International Journal of Immunopathology and Pharmacology 19 761-773
Fledderus JO, van Thienen JV, Boon RA, Dekker RJ, Rohlena J, VOlger OL Bijnens AP, Daemen MJ, Kuiper J, van Berkel TJ, Pannekoek H and Horrevoets AJ (2007) Prolonged shear stress and KLF2 suppress constitutive pro-inflammatory transcription through inhibition of ATF2. Blood in press
Fleenor DL, Pang IH and Clark AF (2003) Involvement of AP-1 in interleukin-1alpha-stimulated MMP-3 expression in human trabecular meshwork cells. Investigative Ophthalmology & Visual Science 44 3494-3501
Fleetwood AJ, Lawrence T, Hamilton JA and Cook AD (2007) Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation.Journal of Immunology 178 5245-5252
Fleischer A, Ghadiri A, Dessauge T, Duhamel M, Rebollo MP, Alvarex-Franco F and Rebollo A (2006) Modulating apoptosis as a target for effective therapy. Molecular Immunology 43 2441-2451
Fleming CM, He H, Ciota A, Perkins D and Finn PW (2001) Administration of pentoxifylline during allergen sensitization dissociates pulmonary allergic inflammation from airway hyperresponsiveness. Journal of Immunology 167 1703-1711
Fleming I, Michaelis UR, Bredenkotter D, Fisslthaler B, Dehghani F, Brandes RP and Busse R (2001) Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries. Circulation Research 88 44-51
Flemming JA, Perkins KH, Luus L, Ferguson AR and Corley RB (2004) Disruption of membrane cholesterol stimulates MyD88-dependent NF-kB activation in immature B cells. Cellular Immunology 229 68-77
Flescher E, Tripoli H, Salnikow K and Burns FJ (1998) Oxidative stress suppresses transcription factor activities in stimulated lymphocytes. Clinical and Experimental Immunology 112 242-247
Fliniaux I, Mikkola ML, Lefebvre S and Thesleff I (2008) Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes. Developmental Biology in press
Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A and Espevik T (2000) Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology 164 2064-2069
Floettmann JE and Rowe M (1997) Epstein-barr virus latent membrane protein-1 (LMP1) C-terminus activation region 2 (CTAR2) maps to the far C-terminus and requires oligomerisation for NF-kB activation. Oncogene 15 1851-1858
Floettmann JE, Eliopoulos AG, Jones M, Young LS and Rowe M (1998) Epstein-barr virus latent membrane protein-1 (LMP1) signalling is distinct from CD40 and involves physical cooperation of its two C-terminus functional regions. Oncogene 17 2382-2392
Flohe SB, Bruggemann J, Lendemans S, Nikulina M, Meierhoff G, Flohe S, Kolb HHuman heat shock protein 60 induces maturation of dendritic cells versus a Th1-promoting phenotype. Journal of Immunology 170 2340-2348
Flora G, Lee YW, Nath A, Hennig B, Maragos W and Toborek M (2003) Methamphetamine potentiates HIV-1 Tat protein-mediated activation of redox-sensitive pathways in discrete regions of the brain. Experimental Neurology 179 60-70
Flora G, Pu H, Hennig B and Toborek M (2006) Cyclooxygenase-2 is involved in HIV-1 Tat-induced inflammatory responses in the brain. Neuromolecular Medicine 8 337-352
Flora G, Pu H, Lee YW, Ravikumar R, Nath A, Hennig B and Toborek M (2005) Proinflammatory synergism of ethanol and HIV-1 Tat protein in brain tissue. Experimental Neurology 191 2-12
Flores N, Duran C, Blasco MR, Puerta C, Dorado B, Garcia-Merino A and Ballester S (2003) NFkB and AP-1 DNA binding activity in patients with multiple sclerosis. Journal of Neuroimmunology 135 141-147
Flores-Saaib RD, Jia S and Courey AJ (2001) Activation and repression by the C-terminal domain of Dorsal. Development 128 1869-1879
Flory E, Kunz M, Scheller C, Jassoy C, Stauber R, Rapp UR and Ludwig S (2000) Influenza virus-induced NF-kB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkB kinase. Journal of Biological Chemistry 275 8307-8314
Flory E, Weber CK, Chen P, Hoffmeyer A, Jassoy C and Rapp UR (1998) Plasma membrane-targeted Raf kinase activates NF-kB and human immunodeficiency virus type 1 replication in T lymphocytes. Journal of Virology 72 2788-2794
Floryk D and Huberman E (2005) Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kB activity. Cancer Research 65 11588-11596
Floyd ZE, Segura BM, He F and Stephens JM (2006) Degradation of STAT5 Proteins in 3T3-L1 Adipocytes is induced by TNFa and cycloheximide in a manner independent of STAT5A activation.American Journal of Physiology: Endocrinology and Metabolism in press
Flynn V Jr, Ramanitharan A, Moparty K, Davis R, Sikka S, Agrawal KC and Abdel-Mageed AB (2003) Adenovirus-mediated inhibition of NF-kB confers chemo-sensitization and apoptosis in prostate cancer cells. International Journal of Oncology 23 317-323
Foell D, Kane D, Bresnihan B, Vogl T, Nacken W, Sorg C, FitzGerald O and Roth J (2003) Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis. Rheumatology 42 1383-1389
Fogel GB, Weekes DG, Varga G, Dow ER, Harlow HB, Onyia JE and Su C (2004) Discovery of sequence motifs related to coexpression of genes using evolutionary computation. Nucleic Acids Research 32 3826-3835
Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, Elling F, Leist M and Jaattela M (2001) Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. Journal of Cell Biology 153 999-1010
Fognani C, Rondi R, Romano A and Blasi F (2000) cRel-TD kinase: a serine/threonine kinase binding in vivo and in vitro c-Rel and phosphorylating its transactivation domain. Oncogene 19 2224-2232
Fohno M, Shimazu T, Aso H, Kawai Y, Saito T and Kitazawa H (2007) Molecular cloning and functional characterization of porcine MyD88 essential for TLR signaling. Cellular and Molecular Immunology 4 369-376
Fohrer H, Audit IM, Sainz A, Schmitt C, Dezutter-Dambuyant C and Dalloul AH (2004) Analysis of transcription factors in thymic and CD34+ progenitor-derived plasmacytoid and myeloid dendritic cells: evidence for distinct expression profiles. Experimental Hematology 32 104-112
Folch-Puy E, Garcia-Movtero A, Iovanna JL, Dagorn JC, Prats N, Vaccaro MI and Closa D (2003) The pancreatitis-associated protein induces lung inflammation in the rat through activation of TNFalpha expression in hepatocytes. Journal of Pathology 199 398-408
Folch-Puy E, Granell S, Dagorn JC, Iovanna JL and Closa D (2006) Pancreatitis-associated protein I suppresses NF-kB activation through a JAK/STAT-mediated mechanism in epithelial cells.Journal of Immunology 176 3774-3779
Folch-Puy E, Granell S, Iovanna JL, Barthet M and Closa D (2006) Peroxisome proliferator-activated receptor gamma agonist reduces the severity of post-ERCP pancreatitis in rats. World Journal ofGastroenterology 12 6458-6463
Foley E and O’Farrell PH (2004) Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biology 2 E203
Foley JF and Vanhook AM (2008) Science signaling podcast: 15 July 2008. Science Signaling 1 pc6
Folgueira L, Algeciras A, MacMorran WS, Bren GD and Paya CV (1996) The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and participates in the activation of NF-kB. Journal of Virology 70 2332-2338
Folgueira L, McElhinny JA, Bren GD, MacMorran WS, Diaz-Meco MT, Moscat J and Paya CV (1995) Protein kinase C-x mediates NF-kB activation in human immunodeficiency virus-infected monocytes. Journal of Virology 70 223-231
Folmer F, Blasius R, Morceau F, Taudravu J, Dicato M, Jaspars M and Diedrich M (2006) Inhibition of TNFa-induced activation of nuclear factor kB by kava (Piper methysticum) derivatives.Biochemical Pharmacology 71 1206-1218
Folmer F, Harrison WT, Tabudravu JN, Jaspars M, Aalbersberg W, Feussner K, Wright AD, Dicato M and Diederich M (2007) NF-kB-Inhibiting Naphthopyrones from the Fijian Echinoderm Comanthus parvicirrus. Journal of Natural Products in press
Folmer F, Jaspars M, Dicato M and Diederich M (2007) Marine natural products as targeted modulators of the transcription factor NF-kB. Biochemical Pharmacology in press
Folwaczny C (2001) [Anti-inflammatory effects of apathogenic salmonellas: relevance for therapy with probiotics?]. Z Gastroenterology 39 329-332
Folwaczny M, Glas J, Torok HP, Mauermann D and Folwaczny C (2004) The 3020insC mutation of the NOD2/CARD15 gene in patients with periodontal disease. European Journal of Oral Science 112 316-319
Foncea R, Carvajal C, Almarza C and Leighton F (2000) Endothelial cell oxidative stress and signal transduction. Biol Res 33 89-96
Fong A and Sun SC (2002) Genetic evidence for the essential role of beta -transducin repeat-containing protein in the inducible processing of NF-kB2/p100. Journal of Biological Chemistry 277 22111-22114
Fong A, Zhang M, Neely J and Sun SC (2002) S9: a 19S proteasome subunit interacting with ubiquitinated NF-kB2/p100. Journal of Biological Chemistry 277 40697-40702
Fong CC, Zhang Q, Shi YF, Wu RS, Fong WF and Yang M (2007)Effect of hypoxia on RAW264.7 macrophages apoptosis and signaling. Toxicology 2335 52-61
Fong CC, Zhang Y, Zhang Q, Tzang CH, Fong WF, Wu RS and Yang M (2007) Dexamethasone protects RAW264.7 macrophages from growth arrest and apoptosis induced by H(2)O(2) through alteration of gene expression patterns and inhibition of nuclear factor-kB (NF-kB) activity. Toxicology 236 16-28
Fong CH, Bebien M, Didierlaurent A, Nebauer R, Hussell T, Broide D, Karin M and Lawrence T (2008) An antiinflammatory role for IKKb through the inhibition of “classical” macrophage activation. Journal of Experimental Medicine in press
Fong F, Tian YP, Huo SH, Hu L, Su JL, Chen H, Wang X, Liu LD, Gao HB and Shi HW (2007) Changes of p38MAPK and nuclear factor-kB in lung tissue of acute paraquat poisoned rats [Article in Chinese]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 25 518-522
Fong LY, Jiang Y, Riley M, Liu X, Smalley KJ, Guttridge DC and Farber JL (2008) Prevention of upper aerodigestive tract cancer in zinc-deficient rodents: inefficacy of genetic or pharmacological disruption of COX-2. International Journal of Cancer 122 978-989
Fong YC, Maa MC, Tsai FJ, Chen WC, Lin JG, Jeng LB, Yang RS, Fu WM and Tang CH (2008) Osteoblast-derived TGF-beta1 stimulates IL-8 release via AP-1 and NF-kB in human cancer cells. Journal of Bone and Mineral Research in press
Fontaine RH, Cases O, Lelievre V, Mesples B, Renauld JC, Loron G, Degos V, Dournaud P, Baud O and Gressens P (2008) IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis. Cell Death and Differentiation in press
Fontaine V, van der Meijden E, de Graaf J, ter Schegget J and Struyk L (2000) A functional NF-kB binding site in the human papillomavirus type 16 long control region. Virology 272 40-49
Fontalba A, Gutierrez O and Fernandez-Luna JL (2007) NLRP2, an inhibitor of the NF-kB pathway, is transcriptionally activated by NF-kB and exhibits a nonfunctional allelic variant. Journal of Immunology 179 8519-8524
Fontalba A, Martinez-Taboada V, Gutierrez O, Pipaon C, Benito N, Balsa A, Blanco R and Fernandez-Luna JL (2007) Deficiency of the NF-kB inhibitor caspase activating and recruitment domain 8 in patients with rheumatoid arthritis is associated with disease severity. Journal of Immunology 179 4867-4873
Fontan E, Traincard F, Levy SG, Yamaoka S, Veron M and Agou F (2007) NEMO oligomerization in the dynamic assembly of the IkB kinase core complex. FEBS Journal 274 2540-2551
Foo SY and Nolan GP (1998) NF-kB to the rescue: RELs, apoptosis and cellular transformation. Trends in Genetics 15 229-235
Forbes JM, Fukami K and Cooper ME (2007) Diabetic nephropathy: where hemodynamics meets metabolism. Experimental and Clinical Endocrinology & Diabetes 115 69-84
Force WR, Glass AA, Benedict CA, Cheung TC, Lama J and Ware CF (2000) Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kB pathways. Journal of Biological Chemistry 275 11121-11129
Forget G, Gregory DJ, Whitcombe LA and Olivier M (2006) Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production. Infection andImmunity 74 6272-6279
Forgues M, Difilippantonio MJ, Linke SP, Ried T, Nagashima K, Feden J, Valerie K, Fukasawa K and Wang XW (2003) Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Molecular and Cellular Biology 23 5282-5292
Foryst-Ludwig A, Neumann M, Schneider-Brachert W and Naumann M (2004) Curcumin blocks NF-kB and the motogenic response in Helicobacter pylori-infected epithelial cells. Biochemical and Biophysical Research Communications 316 1065-1072
Fortin JF, Barat C, Beausejour Y, Barbeau B and Tremblay MJ (2004) Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kB, and AP-1 induction. Journal of Biological Chemistry 279 39520-39531
Fortin JF, Barbeau B, Robichaud GA, Pare ME, Lemieux AM and Tremblay MJ (2001) Regulation of nuclear factor of activated T cells by phosphotyrosyl- specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1. Blood 97 2390-2400
Foryst-Ludwig A and Naumann M (2000) p21-activated kinase 1 activates the nuclear factor kappa B (NF-kB)-inducing kinase-IkB kinases NF-kB pathway and proinflammatory cytokines in Helicobacter pylori infection. Journal of Biological Chemistry 275 39779-39785
Foss F (2003) Overview of cutaneous T-cell lymphoma: prognostic factors and novel therapeutic approaches. Leukemia & Lymphoma 44 S55-S61
Fossati S, Formentini L, Wang ZQ, Moroni F and Chiarugi A (2006) Poly(ADP-ribosyl)ation regulates heat shock factor-1 activity and the heat shock response in murine fibroblasts. Biochemistry and Cell Biology 84 703-712
Foster N, Lovell MA, Marston KL, Hulme SD, Frost AJ, Bland P and Barrow PA (2003) Rapid protection of gnotobiotic pigs against experimental Salmonellosis following induction of polymorphonuclear leukocytes by avirulent Salmonella enterica. Infection & Immunity 71 2182-2191
Fotin-Mleczek M, Henkler F, Hausser A, Glauner H, Samel D, Graness A, Scheurich P, Mauri D and Wajant H (2004) TNF receptor associated factor (TRAF) 1 regulates CD40-induced TRAF2-mediated NF-kB activation. Journal of Biological Chemistry 279 677-679
Fouad D, Siendones E, Costan G and Muntane J (2004) Role of NF-kB activation and nitric oxide expression during PGE protection against d-galactosamine-induced cell death in cultured rat hepatocytes. Liver International 24 227-236
Fouque-Aubert A and Chapurlat R (2007) Influence of RANKL inhibition on immune system in the treatment of bone diseases.Joint Bone Spine in press
Fowler AA, 3rd, Fisher BJ, Sweeney LB, Wallace TJ, Natarajan R, Ghosh SS and Ghosh S (1999) Nitric oxide regulates interleukin-8 gene expression in activated endothelium by inhibiting NF-kB binding to DNA: effects on endothelial function. Biochemistry and Cell Biology 77 201-208
Fox ES, Cantrell CH and Leingang KA (1996) Inhibition of the Kupffer cell inflammatory response by acute ethanol: NF-kB activation and subsequent cytokine production. Biochemical and Biophysical Research Communications 225 134-140
Fox JG, Rogers AB, Whary MT, Ge Z, Taylor NS, Xu S, Horwitz BH and Erdman SE (2004) Gastroenteritis in NF-kB-deficient mice is produced with wild-type Camplyobacter jejuni but not with C. jejuni lacking cytolethal distending toxin despite persistent colonization with both strains. Infection & Immunity 72 1116-1125
Fox JG and Wang TC (2002) Helicobacter pylori infection: pathogenesis.
Current Opinion in Gastroenterology 18 15-25
Fox SW, Fuller K, Chambers TJ (2000) Activation of osteoclasts by interleukin-1: divergent responsiveness in osteoclasts formed in vivo and in vitro. Journal of Cellular Physiology 184 334-340
Fox SW, Haque SJ, Lovibond AC and Chambers TJ (2003) The possible role of TGF-beta-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro. Journal of Immunology 170 3679-3687
Foxwell B, Browne K, Bondeson J, Clarke C, de Martin R, Brennan F and Feldmann M (1998) Efficient adenoviral infection with IkBa reveals that macrophage tumor necrosis factor alpha production in rheumatoid arthritis is NF-kB dependent. Proceedings of the National Academy of Sciences USA 95 8211-8215
Foy E, Li K, Sumpter R Jr, Loo YM, Johnson CL, Wang C, Fish PM, Yoneyama M, Fujita T, Lemon SM and Gale M Jr (2005) Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling. Proceedings of the National Academy of Sciences USA 102 2986-2991
Fracchiolla NS, Lombardi L, Salina M, Migliazza A, Baldini L, Berti E, Cro L, Polli E, Maiolo AT and Neri A (1993) Structural alterations of the NF-kB transcription factor lyt-10 in lymphoid malignancies. Oncogene 8 2839-2845
Fradet V, Lessard L, Begin LR, Karakiewicz P, Masson AM and Saad F (2004) Nuclear factor-kB nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer. Clinical Cancer Research 10 8460-8464
Fragaki K, Kileztky C, Trentesaux C, Zahm JM, Bajolet O, Johnson M and Puchelle E (2006) Down-regulation by a long-acting {beta}2-adrenergic receptor agonist and corticosteroid of Staphylococcus aureus-induced airway epithelial inflammatory mediator production. American Journal of Physiology: Lung Celland Molecular Physiology 291 L11-L18
Francescato HD, Coimbra TM, Costa RS and Bianchi Md M (2004) Protective effect of quercetin on the evolution of cisplatin-induced acute tubular necrosis. Kidney and Blood Pressure Research 27 148-158
Francescato HD, Costa RS, Scavone C and Coimbra TM (2007) Parthenolide reduces cisplatin-induced renal damage. Toxicology230 64-75
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP and Nunez G (2006) Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nature Immunology 7 576-582
Franchi L, Park JH, Shaw MH, Marina-Garcia N, Chen G, Kim YG and Nunez G (2007) Intracellular NOD-like receptors in innate immunity, infection and disease. Cellular Microbiology in press
Franciosi S, Ryu JK, Choi HB, Radov L, Kim SU and McLarnon JG (2006) Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia.
Journal of Neuroscience 26 11652-11664
Francis DA, Karra JG, Ke X, Sen R and Rothstein TL (1995) Induction of the transcription factors NF-kB, AP-1 and NF-AT during B cell stimulation through the CD40 receptor. International Immunology 7 151-161
Francis DA, Sen R, Rice N and Rothstein TL (1998) Receptor-specific induction of NF-kB components in primary B cells. International Immunology 10 285-293
Franco DL, Nojek IM, Molinero L, Coso OA, Costas MA (2002) Osmotic stress sensitizes naturally resistant cells to TNF-a-induced apoptosis. Cell Death & Differentiation 9 1090-1098
Franco R, Camacho FI, Caleo A, Staibano S, Bifano D, De Renzo A, Tranfa F, De Chiara A, Botti G, Merola R, Diez A, Bonavolanta G, De Rosa G and Piris MA (2006) Nuclear bcl10 expression characterizes a group of ocular adnexa MALT lymphomas with shorter failure-free survival. Modern Pathology 19 1055-1067
Francoix M, Richette P, Tsagris L, Fitting C, Lemay C, Benallaoua M, Tahiri K and Corvol MT (2006) Activation of the peroxisome proliferator-activated receptor alpha pathway potentiates interleukin-1 receptor antagonist production in cytokine-treated chondrocytes. Arthritis and Rheumatism 54 1233-1245
Francois S, El Benna J, Dang PM, Pedruzzi E, Gougerot-Pocidalo MA and Elbim C (2005) Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad. Journal of Immunology 174 3633-3642
Franek WR, Chowdary YC, Lin X, Hu M, Miller EJ, Kazzaz JA, Razzano P, Romashko J 3rd, Davis JM, Narula P, Horowitz S, Scott W and Mantell LL (2002) Suppression of nuclear factor-kB activity by nitric oxide and hyperoxia in oxygen resistant cells. Journal of Biological Chemistry 277 42694-42700
Franek WR, Horowitz S, Stansberry L, Kazzaz JA, Koo HC, Li Y, Arita Y, Davis JM, Mantell AS, Scott W and Mantell LL (2001) Hyperoxia inhibits oxidant-induced apoptosis in lung epithelial cells. Journal of Biological Chemistry 276 569-575
Franek WR, Morrow DM, Zhu H, Vancurova I, Miskolci V, Darley-Usmar K, Simms HH and Mantell LL (2004) NF-kB protects lung epithelium against hyperoxia-induced nonapoptotic cell death-oncosis. Free Radiccal Biology and Medicine 37 1670-1679
Frangioudakis G and Cooney Gj (2008) Acute elevation of circulating fatty acids impairs downstream insulin signalling in rat skeletal muscle in vivo independent of effects on stress signalling. Journal of Endocrinology 197 277-285
Frangogiannis NG (2006) Targeting the inflammatory response in healing myocardial infarcts. Current Medicinal Chemistry 13 1877-1893
Frangogiannis NG (2006) The mechanistic basis of infarct healing. Antioxidant and Redox Signaling 8 1907-1939
Frangogiannis NG (2007) Chemokines in ischemia and reperfusion.Thrombosis and Haemostosis 97 738-747
Frangogiannis NG (2008) The immune system and cardiac repair. Phramcology Research in press
Franke S, Siggelkow H, Wolf G and Hein G (2007) Advanced glycation endproducts influence the mRNA expression of RAGE, RANKL and various osteoblastic genes in human osteoblasts.Archives of Physiology and Biochemistry 113 154-161
Frankel SK, Van Linden AA and Riches DW (2001) Heterogeneity in the phosphorylation of human death receptors by p42(mapk/erk2). Biochemical and Biophysical Research Communications 288 313-320
Frankenberger M, Pforte A, Sternsdorf T, Passlick B, Baeuerle PA and Ziegler-Heitbrock HWL (1994) Constitutive nuclear NF-kB in cells of the monocyte lineage. Biochemical Journal 304 87-94
Frankfurt O and Rosen ST (2004) Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates. Current Opinions in Oncology 16 553-563
Franki AS, Beneden KV, Dewint P, Meeus I, Veys E, Deforce D and Elewaut D (2005) Lymphotoxin alpha1beta2: a critical mediator in Valpha14i NKT cell differentiation. Molecular Immunology 42 413-417
Franklin RB, Kang C-Y, Min-min Wan K and Bose Jr HR (1977) Transformation of chick embryo fibroblasts by reticuloendotheliosis virus. Virology 83 313-321
Franklin RB, Maldonado RL and Bose Jr HR (1974) Isolation and characterization of reticuloendotheliosis virus-transformed bone marrow cells. Intervirology 3 342-352
Franscini N, Bachli EB, Blau N, Leikauf MS, Schaffner A and Schoedon G (2004) Gene expression profiling of inflamed human endothelial cells and influence of activated protein C. Circulation 103 2903-2910
Frantz B and O’Neill EA (1995) The effect of sodium salicylate and on NF-kB. Science 270 2017-2018.and Response by Ghosh S and Kopp E (1995) Science 270 2018-2019
Frantz B, Nordby EC, Bren G, Steffan N, Paya CV, Kincaid RL, Tocci MJ, O’Keefe SJ and O’Neill EA (1994) Calcineurin acts in synergy with PMA to inactivate IkB, an inhibitor or NF-kB. EMBO Journal 13 861-870
Frantz S, Fraccarollo D, Wagner H, Behr TM, Jung P, Angermann CE, Ertl G and Bauersachs J (2003) Sustained activation of nuclear factor kB and activator protein 1 in chronic heart failure. Cardiovascular Research 57 749-756
Frantz S, Hu K, Bayer B, Gerondakis S, Strotmann J, Adamek A, Ertle G and Bauersachs J (2006) Absence of NF-kB subunit p50 improves heart failure after myocardial infarction. FASEB Journal 20 1918-1920
Frantz S, Kobzik L, Kim YD, Fukazawa R, Medzhitov R, Lee RT and Kelly RA (1999) Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. Journal of Clinical Investigation 104 271-280
Frantz S, Stoerk S, Ok S, Wagner H, Angermann CE, Ertl G and Bauersachs J (2004) Effect of chronic heart failure on nuclear factor kB in peripheral leukocytes. American Journal of Cardiology 94 671-673
Frantz S, Tillmanns J, Kuhlencordt PJ, Schmidt I, Adamek A, Dienesch C, Thum T, Gerondakis S, Ertl G and Bauersachs J (2007) Tissue-specific effects of the nuclear factor kB subunit p50 on myocardial ischemia-reperfusion injury.
American Journal of Pathology 171 507-512
Franzoso G, Biswas P, Poli G, Carlson L, Brown K, Tomita-Yamaguchi M, Fauci AS and Siebenlist U (1994) A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the Nuclear Factor-kB subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells. Journal of Experimental Medicine 180 1445-1456
Franzoso G, Bours V, Azarenko V, Park S, Tomita-Yamaguchi M, Kanno T, Brown K and Siebenlist U (1993) The oncoprotein Bcl-3 can facilitate NF-kB-mediated transactivation by removing inhibiting p50 homodimers from select kB sites. EMBO Journal 12 3893-3901
Franzoso G, Bours V, Park S, Tomita-Yamaguchi M, Kelly K and Siebenlist U (1992) The candidate proto-oncogene Bcl-3 is an antagonist of p50/NF-kB-mediated inhibition. Nature 359 339-342
Franzoso G, Carlson L, Brown K, Daucher MB, Bressler P and Siebenlist U (1996) Activation of the serum response factor by p65/NF-kB. EMBO Journal 15 3403-3412
Franzoso G, Carlson L, Poljak L, Shores EW, Epstein S, Leonardi A, Grinberg A, Tran T, Scharton-Kerston T, Anver M, Love P, Brown K and Siebenlist U (1998) Mice deficient in NF-kB/p52 present with deficits in humoral responses, germinal center reactions and splenic microarchitecture. Journal of Experimental Medicine 187 147-159
Franzoso G, Carlson L, Scharton-Kersten T, Shores EW, Epstein S, Grinberg A, Tran T, Shacter E, Leonardi A, Anver M, Love P, Sher A and Siebenlist U (1997) Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture and germinal center reactions. Immunity 6 479-490
Franzoso G, Carlson L, Xing L, Poljak L, Shores EW, Brown KD, Leonardi A, Tran T, Boyce BF and Siebenlist U (1997) Requirement for NF-kB in osteoclast and B-cell development. Genes & Development 11 3482-3496
Frasca D, Riley RL and Blomberg BB (2004) Effect of age on the immunoglobulin class switch. Critical Reviews of Immunology 24 297-320
Frasca D, Riley RL and Blomberg BB (2006) Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF.Experimental Gerontology 42 192-203
Fraser CC (2006) Exploring the positive and negative consequences of NF-kB inhibition for the treatment of human disease. Cell Cycle 5 1160-1163
Fraser DA, Arora M, Bohlson SS, Lozano E and Tenner AJ (2007) Generation of inhibitory NFkB complexes and pCREB correlates with the anti-inflammatory activity of complement protein C1q in human monocytes. Journal of Biological Chemistry 282 7360-7367
Fraser JH, Rincon M, McCoy KD and Le Gros G (1999) CTLA4 ligation attenuates AP-1, NFAT and NF-kB activity in activated T cells. European Journal of Immunology 29 838-844
Fraser SA, De Haan L, Hearn AR, Bone HK, Salmond RJ, Rivett AJ, Williams NA and Hirst TR (2003) Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions. Infection & Immunity 71 1527-1537
Frassanito MA, Mastromauro L, Cusmai A and Dammacco F (2005) Blockade of the Ras pathway by manumycin, a farnesyltransferase inhibitor, overcomes the resistance of myeloma plasma cells to Fas-induced apoptosis. Clinical and Experimental Medicine 4 174-182
Frassdorf J, Weber NC, Obal D, Toma O, Mullenheim J, Kojda G, Preckel B and Schlack W (2005) Morphine induces late cardioprotection in rat hearts in vivo: the involvement of opioid receptors and nuclear transcription factor kB. Anesthesia and Analgesia 101 934-941
Fratelli M, Goodwin LO, Orom UA, Lombardi S, Tonelli R, Mengozzi M and Ghezzi P (2005) Gene expression profiling reveals a signaling role of glutathione in redox regulation. Proceedings of the National Academy of Sciences USA 102 13998-14003
Fratelli M, Minto M, Crespi A, Erba E, Vandenabeele P, Del Soldato P and Ghezzi P (2003) Inhibition of nuclear factor-kB by a nitro-derivative of flurbiprofen: a possible mechanism for antiinflammatory and antiproliferative effect. Antioxidant and Redox Signaling 5 229-235
Fraunberger P, Wang Y, Blessing FJ, Seidel D and Walli AK (2005) Atherogenesis: interplay between cholesterol, inflammation and coagulation [Article in German]. Herz 30 723-732
Frazier-Jessen MR, Thompson CD, Brown R, Rawat R, Nordan RP, Feldman GM (2002) NF-kB elements contribute to junB inducibility by lipopolysaccharide in the murine macrophage cell line RAW264.7. FEBS Letters 513 203-207
Frede S, Stockmann C, Freitag P and Fandrey J (2006) Bacterial lipopolysaccharides induce HIF-1 activation in human monocytes via p44/42 MAPK and NF-kB. Biochemical Journal 396 517-527
Fredericks ZL, Forte C, Capuano IV, Zhou H, Vanden Bos T and Carter P (2004) Identification of potent human anti-IL-1RI antagonist antibodies. Protein Eng Des Sel 17 95-106
Freebern WJ, Haggerty CM, Montano I, McNutt MC, Collins I, Graham A, Chandramoui GV, Stewart DH, Biebuyck HA, Taub DD and Gardner K (2005) Pharmacologic profiling of transcriptional targets deciphers promoter logic. Pharmacogenomics Journal 5 305-323
Freedman AR, Sharma RJ, Nabel GJ, Emerson SG and Griffin GE (1992) Cellular distribution of NF-kB binding activity in rat liver. Biochemical Journal 287 645-649
Freemerman AJ, Gallegos A and Powis G (1999) Nuclear factor kB transactivation is increased but is not involved in the proliferative effects of thioredoxin overexpression in MCF-7 breast cancer cells. Cancer Research 59 4090-4094
Frei B and Higdon JV (2003) Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. Journal of Nutrition 133 3275S-3284S
Freire-Garabal M, Nunez MJ, Balboa J, Lopez-Delgado P, Gallego R, Garcia-Caballero T, Fernandez-Roel MD, Brenlla J and Rey-Mendez M (2003) Serotonin upregulates the activity of phagocytosis through 5-HT(1A) receptors. British Journal Pharmacology 139 457-463
Frelin C, Imbert V, Bottero V, Gontheier N, Samraj AK, Schulze-Osthoff K, Auberger P, Courtois G and Peyron JF (2008) Inhibition of the NF-kB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kB essential modulator NEMO. Cell Death and Differentiation 15 152-160
Frelin C, Imbert V, Griessinger E, Loubat A, Dreano M and Peyron JF (2003) AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-a in Jurkat leukemic cells. Oncogene 22 8187-8194
Frelin C, Imbert V, Griessinger E, Peyron AC, Rochet N, Philip P, Dageville C, Sirvent A, Hummelsberger M, Berard E, Dreano M, Sirvent N and Peyron JF (2005) Targeting NF-kB activation via pharmacological inhibition of IKK2 induced apoptosis of human acute myeloid leukemia cells. Blood 105 804-811
Fremont M, Vaeyens F, Herst CV, De Meirleir KL and Englebienne P (2006) Double-stranded RNA-dependent protein kinase (PKR) is a stress-responsive kinase that induces NFkB-mediated resistance against mercury cytotoxicity. Life Sciences 78 1845-1856
French J, Stirling R, Walsh M and Kennedy HD (2002) The expression of Ras-GTPase activating protein SH3 domain-binding proteins, G3BPs, in human breast cancers. Histochemical Journal 34 223-231
Frenette AJ, Perreault MM, Lam S and Williamson DR (2007) Thiopental-induced neutropenia in two patients with severe head trauma. Pharmacotherapy 27 464-471
Frenkel L, Freudenthal R, Romano A, Nahmod VE, Maldonado H and Delorenzi A (2002) Angiotensin II and the transcription factor Rel/NF-kB link environmental water shortage with memory improvement. Neuroscience 115 1079-1087
Frensing T, Kaltschmidt C and Schmitt-John T (2008) Characterization of a neuregulin-1 gene promoter: Positive regulation of type I isoforms by NF-kB. Biochimica et Biophysica Acta 1779 139-144
Fresco P, Borges F, Diniz C and Marques MP (2006) New insights on the anticancer properties of dietary polyphenols. Medical Research Reviews 26 747-766
Freter RR, Alberta JA, Hwang GY, Wrentmore AL and Stiles CD (1996) Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kB and a 90-kDa phosphoprotein coactivator. Journal of Biological Chemistry 271 17417-17424
Freudenthal R, Boccia MM, Acosta GB, Blake MG, Merlo E, Baratti CM and Romano A (2005) NF-kB transcription factor is required for inhibitory avoidance long-term memory in mice. European Journal of Neuroscience 21 2845-2852
Freudenthal R and Romano A (2000) Participation of Rel/NF-kB transcription factors in long-term memory in the crab Chasmagnathus. Brain Research 855 274-281
Freudenthal R, Romano A and Routtenberg A (2004) Transcription factor NF-kB activation after in vivo perforant path LTP in mouse hippocampus. Hippocampus 14 677-683
Freund A, Jolivel V, Durand S, Kersual N, Chalbos D, Chavey C, Vignon F and Lazennec G (2004) Mechanisms underlying differential expression of interleukin-8 in breast cancer cells. Oncogene 23 6105-6114
Freund C, Schmidt-Ullrich R, Baurand A, Dunger S, Schneider W, Loser P, El-Jamali A, Dietz R, Scheidereit C and Bergmann MW (2005) Requirement of nuclear factor-kB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo. Circulation111 2319-2325
Freund-Michel V and Frossard N (2007) The nerve growth factor and its receptors in airway inflammatory diseases. Pharmacology & Therapeutics 117 52-76
Frey RS, Gao X, Javaid K, Siddiqui SS, Rahman A and Malik AB (2006) Phosphatidylinositol 3-kinase gamma signaling through PKCzeta induces NADPH oxidase-mediated oxidant generation and NF-kB activation in endothelial cells. Journal of BiologicalChemistry 281 16128-16138
Freyschmidt EJ,Mathias CB, Macarthur DH, Laouar A, Narasimhaswamy M, Weih F and Oettgen HC (2007) Skin inflammation in RelB(-/-) mice leads to defective immunity and impaired clearance of vaccinia virus. Journal of Allergy and Clinical Immunology 119 671-679
Frias-Staheli N, Giannakopoulos NV, Kikkert M, Taylor SL, Bridgen A, Paragas J, Richt JA, Rowland RR, Schmaljohn CS, Lenschow DJ, Snijder EJ, Garcia-Sastre A and Virgin 4th HW (2007) Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses. Cell Host Microbe 2 404-416
Fribley A and Wang CY (2006) Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress. Cancer Biology & Therapy 5 745-748
Fribley A, Zeng Q and Wang CY (2004) Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells. Molecular and Cellular Biology 24 9695-9704
Frick JS, Fink K, Kahl F, Niemiec MJ, Quitadamo M, Schenk K and AUtenrieth IB (2007) Identification of commensal bacterial strains modulating Yersinia and DSS-induced inflammatory responses: implications for the development of probiotics.Infection and Immunity 13 83-90
Frick JS, Schenk K, Quitadamo M, Kahl F, Koberle M, Bohn E, Aepfelbacher M and Autenrieth IB (2007) Lactobacillus fermentum attenuates the proinflammatory effect of Yersinia enterocolitica on human epithelial cells. Inflammatory Bowel Disease 13 83-90
Fridmacher V, Kaltschmidt B, Goudeau B, Ndiaye D, Rossi FM, Pfeiffer J, Kaltschmidt C, Israel A and Memet S (2003) Forebrain-specific neuronal inhibition of nuclear factor-kB activity leads to loss of neuroprotection. Journal of Neuroscience 23 9403-9408
Fried L and Arbiser JL (2008) The reactive oxygen-driven tumor: relevance to melanoma. Pigment Cell and Melanoma Research 21 117-122
Friedl R, Pichler I, Spieckermann P and Moeslinger T (2005) Oxidized phospatidylcholine but not native phosphatidylcholine inhibits inducible nitric oxide synthase in RAW 264.7 macrophages. Life Science 78 1586-1591
Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D and Weaver VM (2007) {alpha}6{beta}4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kB-dependent resistance to apoptosis in 3D mammary acini. Journal of Cell Science 120 370-3712
Friedland JS, Constantin D, Shaw TC and Stylianou E (2001) Regulation of interleukin-8 gene expression after phagocytosis of zymosan by human monocytic cells. Journal of Leukocyte Biology 70 447-454
Friedman AD (2007) C/EBPalpha induces PU.1 and interacts with AP-1 and NF-kB to regulate myeloid development. Blood Cells,Molecules & Disease 39 340-343
Friedman AD (2007) Transcriptional control of granulocyte and monocyte development. Oncogene 26 6816-6828
Friedman JM and Horwitz MS (2002) Inhibition of tumor necrosis factor alpha-induced NF-kB activation by the adenovirus E3-10.4/14.5K complex. Journal of Virology 76 5515-5521
Friedman R (2000) Pain at the cellular level: the role of the cytokine tumor necrosis factor-alpha. Reg Anesth Pain Med 25 110-112
Friedman R and Hughes AL (2002) Molecular evolution of the NF-kB signaling system. Immunogenetics 53 964-974
Friedman SL (2006) Transcriptional regulation of stellate cell activation. Journal of Gastroenterology and Hepatology 21 S79-S83
Friedrichs F, Henckaerts L, Vermieire S, Kucharzik T, Seehafer T, Moller-Krull M, Bornberg-Bauer E, Stoll M and Weiner J (2008) The Crohn’s disease susceptibility gene DLG5 as a member of the CARD interaction network. Journal of Molecular Medicine 86 423-432
Friedrichsen S, Harper CV, Semprini S, Wilding M, Adamson AD, Spiller DG, Nelson G, Mullins JJ, White MR and Davis JR (2006) TNF-a activates the human prolactin gene promoter via NF-kB signaling. Endocrinology 147 773-781
Frier BC, Noble EG and Locke M (2008) Diabetes-induced atrophy is associated with a muscle-specific alteration in NF-kB activation and expression. Cell Stress and Chpaerones in press
Fries DM, Paxinou E, Themistocleous M, Swanberg E, Griendling KK, Salvemini D, Slot JW, Heijnen HF, Hazen SL and Ischiropoulos H (2003) Expression of inducible nitric oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: Role of reactive oxygen species. Journal of Biological Chemistry 278 22901-22907
Fries JW, Roth T, Dienes HP, Weber M and Odenthal M (2003) A novel evaluation method for paraffinized human renal biopsies using quantitative analysis of microdissected glomeruli and VCAM-1 as marker of inflammatory mesangial cell activation. Nephrology, Dialysis and Transplantation 18 710-716
Fries KL, Miller WE and Raab-Traub N (1996) Epstein-Barr virus latent membrane protein 1 blocks p53-mediated apoptosis through the induction of the A20 gene. Journal of Virology 70 8653-8659
Fries KL, Miller WE and Raab-Traub N (1999) The A20 protein interacts with the Epstein-Barr virus latent membrane protein 1 (LMP1) and alters the LMP1/TRAF1/TRADD complex. Virology 264 159-166
Friess M, Engelhardt P, Dobbelaere D, Zurbriggen A and Grone A (2005) Reduced nuclear translocation of nuclear factor (NF)-kB p65 in the footpad epidermis of dogs infected with Distemper Virus. Journal of Comparative Pathology 132 82-89
Frith MC, Fu Y, Yu L, Chen JF, Hansen U and Weng Z (2004) Detection of functional DNA motifs via statistical over-representation. Nucleic Acids Research 32 1372-1381
Fritz A, Brayer KJ, McCormick N, Adams DG, Wadzinski BEa nd Vaillancourt RR (2006) Phosphorylation of serine 526 is required for MEKK3 activity and association with 14-3-3 blocks dephosphorylation. Journal of Biological Chemistry 281 6236-6245
Fritz EA, Glant TT, Vermes C, Jacobs JJ and Roebuck KA (2002) Titanium particles induce the immediate early stress responsive chemokines IL-8 and MCP-1 in osteoblasts. Journal of Orthopedic Research 20 490-498
Fritz EA, Jacobs JJ, Glant TT and Roebuck KA (2005) Chemokine IL-8 induction by particulate wear debris in osteoblasts is mediated by NF-kB. Journal of Orthopedic Research 23 1249-1257
Fritz G and Kaina B (2000) Ras-related GTPase RhoB forces alkylation-induced apoptotic cell death. Biochemical and Biophysical Research Communications 268 784-789
Fritzenwanger M, Kuethe F, Haase D, Jandt E and Figulla HR (2006) Cardiotrophin-1 induces monocyte chemoattractant protein-1 synthesis in human umbilical vein endothelial cells. Cytokine33 46-51
Froese N, Schwarzer M, Niedick I, Frischmann Y, Koster M,Kroger A, Mueller PP, Nourbakhsh M, Pasche B, Reimann J, Staeheli P and Hauser H (2006) Innate immune responses in NF-kB-repressing factor-deficient mice. Molecular and Cellular Biology 26 293-302
Frolet C, thoma M, Blandin S, Hoffmann JA and Levashina EA (2006) Boosting NF-kB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei. Immunity 25677-685
Frommer KW, Reichenmiller K, Schutt BS, Hoeflich A, Ranke MB, Dodt G and Elmlinger MW (2006) IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T. Journal ofMolecular Endocrinolgoy 37 13-23
Frondoza CG, Sohrabi A, Polotsky A, Phan PV, Hungerford DS and Lindmark L (2004) An in vitro screening assay for inhibitors of proinflammatory mediators in herbal extracts using human syovioctye cultures. In Vitro Cell Dev Biol Anim 40 95-101
Frossard JL, Pastor CM and Hadengue A (2001) Effect of hyperthermia on NF-kB binding activity in cerulein- induced acute pancreatitis. Am J Physiol Gastrointest Liver Physiology 280 G1157-G1162
Frost RA and Lang CH (2008) Regulation of muscle growth by pathogen-associated molecules. Journal of Animal Science 86 E84-E93
Frost RA, Nystrom GJ and Lang CH (2004) Lipopolysaccharide stimulates nitric oxide synthase-2 expression in mouse skeletal muscle and C2C12 myoblasts via Toll-like receptor-4 and c-Jun NH2-terminal kinase pathways. American Journal of Physiology: Cellular Physiology 287 C1605-C1615
Froy A (2005) Regulation of mammalian defensin expression by Toll-like receptor-dependent and independent signalling pathways. Cellular Microbiology 7 1387-1397
Fry RC, Navasumrit P, Valiathan C, Svensson JP, Hogan BJ, Luo M, Bhattacharya S, Kandjanapa K, Soontararuks S, Nookabkaew S, Mahidol C, Ruchirawat M and Samson LD (2007) Activation of inflammation/NF-kB signaling in infants bron to arsenic-exposed mothers. PLoS Genetics in press
Fu D, Kobayashi M and Lin L (2004) A p105-based inhibitor broadly represses NF-kB activities. Journal of Biological Chemistry 279 12819-12826
Fu DX, Kuo YL, Liu BY, Jeang KT and Giam CZ (2002) Human T-lymphotropic virus type I tax activates I-kB kinase by inhibiting IKKg-associated serine/threonine protein phosphatase 2A. Journal of Biological Chemistry 278 1487-1493
Fu ES, Zhang YP, Sagen J and Bethea JR (2006) Role of glial NF-kB inhibition on pain behavior after sciatic constriction nerve injury in mice. Journal of Neurosurgical Anesthesiology 18 313-314
Fu HQ, Tao GS, Zhang J and Li Z (2007) Inhibitory effect of quercetin on cervix cancer in mice [Article in Chinese]. Zhong Nan Da Xue Xue Bao Yi Xue Ban 32 890-894
Fu HY, Yabe Y, Asahi K, Hayashi T, Murata H, Eguchi H, Tsujii M, Tsuji S and Kawano S (2005) (2E,6Z,10E)-7-hydroxymethyl-3,11,15-trimethyl-2,6,10,14-hexadecatetraen-1-ol (Plaunotol) increases cyclooxygenase-2 expression via nuclear factor kappaB and cyclic AMP response element in rat gastric epithelial cells. European Journal of Pharmacology 524 38-43
Fu L, Lin-Lee YC, Pham LV, Tamayo A, Yoshimura L and Ford RJ (2006) Constitutive NF-kB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B cell lymphomas. Blood 107 4540-4548
Fu SL, Hsu YH, Lee PY, Hou WC, Hung LC, Lin CH, Chen CM and Huang YJ (2005) Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages. Biochemical and Biophysical Research Communications 339 137-144
Fu W, Guo Y, Huang D, Shang C and Sun K (2007) Novel partners of S100A8 identified in laryngeal cancer cell lines [Article in Chinese[. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24 266-270
Fu Y, Pei DS, Sun B, Shen WH, Lu L, Hu SQ and Zhao HR (2003) Identification of important amino acid residues for human IL-18 function by mutant construction [Article in Chinese]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 35 409-415
Fu Y, Xie C, Yan M, Li Q, Joh JW, Lu C and Mohan C (2005) The lipopolysaccharide-triggered mesangial transcriptome: Evaluating the role of interferon regulatory factor-1. Kidney International 67 1350-1361
Fu Z, Bettega K, Carroll S, Buchholz KR and Machen TE (2007) Role of Ca2+ in responses of airway epithelia to P. aeruginosai, flagellin, ATP and thapsigargin. American Journal of Physiology:Lung Cellular and Molecular Physiology 292 L353-L364
Fuchs C, Forster V, Balse E, Sahel JA, Picaud S and Tessier LH (2005) Retinal-cell-conditioned medium prevents TNF-a-induced apoptosis of purified ganglion cells. Investigative Ophthalmology and Visual Science 46 2983-2991
Fuchs O and Neuwirtova R (2006) Ubiquitins, proteasomes, sumoylation and application today and in future for cancer and other diseases therapy I. Ubiquitin-proteasome system and the transcription factor NF-kB [Article in Czech]. Vnitr Lek 52371-378
Fuchs S, Resch K, Thiel C, Ulbrich M, Platzer M, Jockusch H and Schmitt-John T (2002) Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14. BMC Genet 3 14
Fuchs SY, Chen A, Xiong Y, Pan Z-Q and Ronai Z (1999) HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkB and b-catenin. Oncogene 18 2039-2046
Fuchs SY, Fried VA and Ronai Z (1998) Stress-activated kinases regulate protein stability. Oncogene 17 1483-1490
Fuentes Jm, Talamani MA, Fulton WB, Hanly EJ, Aurora AT and De Maio A (2006) General anesthesia delays the inflammatory response and increases survival for mice with endotoxic shock.Clinical Vaccine Immunology 13 281-288
Fuhrmann H, Miles EA, West AL and Calder PC (2007) Membrane fatty acids, oxidative burst and phagocytosis after enrichment of P388D1 monocyte/macrophages with essential 18-carbon fatty acids. Annals of Nutrition and Metabolism 51 155-162
Fuhrmann O, Arvand M, Gohler A, Schmid M, Krull M, Hippenstiel S, Seybold J, Dehio C and Suttorp N (2001) Bartonella henselae induces NF-kB-dependent upregulation of adhesion molecules in cultured human endothelial cells: possible role of outer membrane proteins as pathogenic factors. Infection & Immunity 69 5088-5097
Fuji T, Yonemitsu Y, Onimaru M, Inoue M, Kasegawa M, Kuwano H and Sueishi K (2008) VEGF function for upregulation of endogenous PlGF expression during FGF-2-mediated therapeutic angiogenesis. Atheroslcerosis in press
Fujigaki H, Saito K, Fujigaki S, Takemura M, Sudo K, Ishiguro H and Seishima M (2006) The signal transducer and activator of transcription 1a and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide: involvement of p38 mitogen-activated protein kinase and nuclear factor-kB pathways, and synergistic effect of several proinflammatory cytokines. Journal of Biochemistry(Tokyo) 139 655-662
Fujihara CK, Antunes GR, Mattar AL, Malheiros DM, Biera Jr JM and Zatz R (2007) Chronic inhibition of nuclear factor-kB attenuates renal injury in the 5/6 renal ablation model. American Journal of Renal Physiology 292 F92-F99
Fujihara M, Wakamoto S, Ito T, Muroi M, Suzuki T, Ikeda H and Ikebuchi K (2000) Lipopolysaccharide-triggered desensitization of TNF-a mRNA expression involves lack of phosphorylation of IkBa in a murine macrophage-like cell line, P388D1. Journal of Leukocyte Biology 68 267-276
Fujihara S, Jaffray E, Farrow SN, Rossi AG, Haslett C and Hay RT (2005) Inhibition of NF-kB by a cell permeable form of IkBa induces apoptosis in eosinophils. Biochemical and Biophysical Research Communications 326 632-637
Fujihara SM and Nadler SG (1999) Intranuclear targeted delivery of functional NF-kB by 70 kDa heat shock protein. EMBO Journal 18 411-419
Fujii A, Harada T, Yamauchi N, Iwabe T, Nishi Y, Yanase T, Nawata H and Terakawa N (2003) Interleukin-8 gene and protein expression are up-regulated by interleukin-1beta in normal human ovarian cells and a granulosa tumor cell line. Fertility and Sterility 79 151-157
Fujii H (2005) Anti-inflammatory action of PPARs [Article in Japanese]. Nippon Rinsho 63 609-615
Fujii M, Minamino M, Nomura M, Miyamoto K-I, Tanaka J and Seiki M (1996) Selective activation of the proto-oncogene c-junpromoter by the transforming protein v-Rel. Oncogene 12 2193-2202
Fujii M, Minamino T, Nomura M, Miyamoto K, Tanaka J and Seiki M (1997) v-Rel activates the proto-oncogene c-Jun promoter: a corrlation with its transforming activity. Leukemia 11 402-404
Fujii M, Sassone-Corsi P and Verma IM (1988) c-fos promoter transactivation by the tax-1 protein of human T-cell leukemia virus type I. Proceedings of the National Academy of Sciences USA 85 8526-8530
Fujii S, Maeda H, Wada N, Kano Y and Akamine A (2006) Establishing and characterizing human periodontal ligament fibroblasts immortalized by SV40 T-antigen and hTERT gene transfer. Cell and Tissue Research 324 117-125
Fujii T, Yonemitsu Y, Otimaru M, Inoue M, Hasegawa M, Kuwano H and Sueishi K (2008) VEGF function for upregulation of endogenous PlGF expression during FGF-2-mediated therapeutic angiogenesis. Atherosclerosis in press
Fujii Y, Fujii K and Tanaka Y (2006) Attempt to correct abnormal signal transduction in T lymphocytes from systemic lupus erythematosus patients.
Autoimmunity Reviews 5 143-144
Fujikawa K (1992) Synergism between transcription factors NF-IL6 and NF-kB in IL-6 gene regulation. Hokkaido Journal of Medical Science 67 563-574
Fujikawa Y, Itonaga Ik Kudo O, Hirayama T and Taira H (2005) Macrophages that have phagocytosed particles are capable of differentiating into functional osteoclasts. Modern Rheumatology 15 346-351
Fujiki H, Suganuma M, Okabe S, Kurusu M, Imai K and Nakachi K (2002) Involvement of TNF-alpha changes in human cancer development, prevention and palliative care. Mechanisms of Ageing and Development 123 1655-1663
Fujiki H, Suganuma M, Okabe S, Sueoka E, Suga K, Imai Kazue, Nakachi K (1999) A new concept of tumor promotion by tumor necrosis factor-a, and cancer preventive agents (-)-Epigallocatechin gallate and green tea – A review. Cancer Detection and Prevention 24 91-99
Fujimori K, Fujitani Y, Kadoyama K, Kumanogoh H, Ishikawa K and Urade Y (2002) Regulation of lipocalin-type prostaglandin D synthase gene expression by Hes-1 through E-box and interleukin-1b via two NF-kB elements in rat leptomeningeal cells. Journal of Biological Chemistry 278 6018-6026
Fujimoto A, Kimura R, Ohashi J, Omi K, Yuliwulandari R, Batubara L, Mustofa MS, Samakkarn U, Settheetham-Ishida W, Ishida T, Morishita Y, Furusawa T, Nakazawa M, Ohtsuka R and Tokunaga K (2008) A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Human Molecular Genetics 17 835-843
Fujimoto H, D’Alessandro-Gabazza CN, Palanki MS, Erdman PE, Takagi T, Gabazza EC, Bruno NE, Yano Y, Hayashi T, Tamaki S, Sumida Y, Adachi Y, Suzuki K and Taguchi O (2007) Inhibition of nuclear factor-kB in T cells suppresses lung fibrosis. AmericanJournal of Respiratory and Critical Care Medicine 176 1251-1260
Fujimoto K, Yasuda H, Sato Y and Yamamoto K-i (1995) A role for phosphorylation in the proteolytic processing of the NF-kB1 precursor. Gene 165 183-189
Fujimura Y, Hotokezaka H, Ohara N,Naito M, Sakai E, Yoshimura M, Narita Y, Kitaura H, Yoshida N and Nakayama K (2006) The hemoglobin receptor protein of Porphyromonas gingivalis inhibits receptor activator NF-kB ligand-induced osteoclastogenesis from bone marrow macrophages. Infection and Immunity 74 2544-2551
Fujino RS, Tanaka K, Morimatsu M, Tamura K, Kogo H and Hara T (2005) Spermatogonial cell-mediated activation of an IkBz-independent NF-kB pathway in Sertoli cells induces transcription of the lipocalin-2 gene. Molecular Endocrinology 20 904-915
Fujioka S, Niu J, Schmidt C, Sclabas GM, Peng B, Uwagawa T, Li Z, Evans DB, Abbruzzese JL and Chiao PJ (2004) NF-kB and AP-1 connection: mechanism of NF-kB-dependent regulation of AP-1 activity. Molecular and Cellular Biology 24 7806-7819
Fujioka S, Schmidt C, Sclabas GM, Li Z, Pelicano H, Peng B, Yao A, Niu J, Zhang W, Evans DB, Abbruzzese JL, Huang P and Chiao PJ (2004) Stabilization of p53: a novel mechanism for proapoptotic function of NF-kB. Journal of Biological Chemistry 279 27549-27559
Fujioka S, Sclabas GM, Schmidt C, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C and Chiao PJ (2003) Function of nuclear factor kB in pancreatic cancer metastasis. Clinical Cancer Research 9 346-354
Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C and Chiao PJ (2003) Inhibition of constitutive NF-kB activity by IkBaM suppresses tumorigenesis. Oncogene 22 1365-1370
Fujisaki K, Tanabe N, Suzuki N, Kawato T, Takeichi O, Tsuzukibashi O, Makimura M, Ito K and Maeno M (2007) Receptor activator of NF-kB ligand induces the expression of carbonic anhydrase II, cathepsin K, and matrix metalloproteinase-9 in osteoclast precursor RAW264.7 cells. Life Sciences 80 1311-1318
Fujishiro N, Anan H, Hamachi T and Maeda K (2008) The role of macrophages in the periodontal regeneration using Emdogain gel. Journal of Periodontal Research 43 143-155
Fujita A, Sato J, Garay-Malpartida H, Morettin P, Sogayar M and Ferreira C (2007) Time-varying modeling of gene expression regulatory networks using the wavelet dynamic vector autoregressive method. Bioinformatics 23 1623-1630
Fujita F, Taniguchi Y, Kato T, Narita Y, Furuya A, Ogawa T, Sakurai H, Joh T, Itoh M, Delhase M, Karin M and Nakanishi M (2003) Identification of NAP1, a regulatory subunit of IkB Kinase-related kinases that potentiates NF-kB signaling. Molecular and Cellular Biology 23 7780-7793
Fujita H, Morita I and Murota S (1999) A possible involvement of ion transporter in tumor necrosis factor alpha and cycloheximide-induced apoptosis of endothelial cells. Mediators of Inflammation 8 211-218
Fujita KI and Janz S (2007) Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF. Molecular Cancer 6 71
Fujita M, Goto K, Yoshida K, Okamura H, Morimoto H, Kito S, Fukuda J and Haneji T (2004) Okadaic acid stimulates expression of Fas receptor and Fas ligand by activation of nuclear factor kB in human oral squamous carcinoma cells. Oral Oncology 40 199-206
Fujita M, Hayashi I, Yamashina S, Fukamizu A, Itoman M and Majima M (2005) Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth. Carcinogenesis 26 271-279
Fujita M, Into T, Yasuda M, Okusawa T, Hamahira S, Kuroki Y, Eto A, Nisizawa T, Morita M and Shibata KI (2003) Involvement of leucine residues at positions 107, 112, and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoproteins and lipopeptides and Staphylococcus aureus peptidoglycans. Journal of Immunology 171 3675-3683
Fujita M, Masamune A, Satoh A, Sakai Y, Satoh K and Shimosegawa T (2001) Ascites of rat experimental model of severe acute pancreatitis induces lung injury. Pancreas 22 409-418
Fujita M, Okuda H, Tsukamoto O, Asano Y, Liao Y, Hirata A, Kim J, Miyatsuka T, Takshima S, Minamino T, Tomoike H and Kitakazeba M (2006) Blockade of angiotensin II receptors reduces the expression of receptors for advanced glycation end products in human endothelial cells. Arteriosclerosis, Thrombosis andVascular Biology 26 e138-e142
Fujita T (1999) Signal dependent nuclear localization of regulatory transcription factors [Article in Japanese]. Tanpakushitsu Kakusan Koso 44 1914-1919
Fujita T, Nolan GP, Ghosh S and Baltimore D (1992) Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kB. Genes & Development 6 775-787
Fujita T, Doihara H, Washio K, Ino H, Murakami M, Naito M and SHimizu N (2007) Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cells.Anticancer Drugs 18 677-686
Fujita T, Nolan GP, Liou H-S, Scott ML and Baltimore D (1993) The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kB p50 homodimers. Genes & Development 7 1354-1363
Fujita T and Suhara W (2000) IkB kinase (IKK) complex [Article in Japanese]. Tanpakushitsu Kakusan Koso 45 1546-1550
Fujita T, Washio K, Takabatake D, Takahashi H, Yoshitomi S, Tsukuda K, Ishibe Y, Ogasawara Y, Doihara H and Shimizu N (2005) Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance. International Journal of Cancer 117 670-682
Fujiwara M, Okamoto M, Ijichi K, Tokuhisa K, Hanasaki Y, Katsura K, Uemura D, Shigeta S, Konna K, Yokota T and Baba M (1998) Upregulation of HIV-1 replication in chronically infected cells by ingenol derivatives. Archives Virology 143 2003-2010
Fujiwara N, Fusaki N and Hozumi N (2004) CD72 stimulation modulates anti-IgM induced apoptotic signaling through the pathway of NF-kB, c-Myc and p27(Kip1). Microbiology and Immunology 48 59-66
Fukagawa NK, Li M, Timblin CR and Mossman BT (2001) Modulation of cell injury and survival by high glucose and advancing age. Free Radical Biology and Medicine 31 1560-1569
Fukata M and Abreu MT (2008) Role of Toll-like receptors in gastrointestinal malignancies. Oncogene 27 234-243
Fukuda K, Fujitsu Y, Kimagai N and Nishida T (2006) Inhibition of matrix metalloproteinase-3 synthesis in human conjunctival fibroblasts by interleukin-4 or interleukin-13. InvestigativeOphthalmology & Visual Science 47 2857-2864
Fukuda K, Kumagai N, Yamamoto K, Fujitsu Y, Chikamoto N and Nishida T (2005) Potentiation of lipopolysaccharide-induced chemokine and adhesion molecule expression in corneal fibroblasts by soluble CD14 or LPS-binding protein.Investigative Ophthalmology & Visual Science 46 3095-3101
Fukuda K, Tsujita T, Matsumoto M, Seya T, Sakyama H, Nishikawa F, Nishikawa S and Hasegawa T (2006) Analysis of the interaction between human TLR3 ectodomain and nucleic acids. Nucleic Acids Symposium Series (Oxford) 50 249-250
Fukuda M, Fukuda F, Horiuchi Y, Oku Y, Suzuki S, Kusama K and Skashita H (2006) Expression of CYLD, NF-kB and NF-kB-related factors in salivary gland tumors. In Vivo 20 467-472
Fukuda M, Hiroi M, Suzuki S, Ohmori Y and Sakashita H (2008) Loss of CYLD might be associated with development of salivary gland tumors. Oncology Resports 19 1421-1427
Fukuda M, Kurosaki W, Yanagihara K, Kuratsune H and Sairenji T (2002) A mechanism in Epstein-Barr Virus oncogenesis: inhibition of transforming growth factor-beta1-mediated induction of MAPK/p21 by LMP1. Virology 302 310-320
Fukuda S, Kaga S, Zhan L, Bagchi D, Das DK, Bertelli A and Maulik N (2006) Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor flk-1. Cell Biochemistry and Biophysics 44 43-50
Fukuda T, Chen L, Endo T, Tang L, Lu D, Castro JE, Widhopf 2nd GF, Rassenti LZ, Cantwell MJ, Prussak CE, Carson DA and Kipps TJ (2008) Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a. Proceedings of the National Academy of Sciences USA 105 3047-3052
Fukada T, Ono M, Sakata S, Kioka N, Sakai H and Komano T (2003) Genomic structure and 5′-flanking sequences of rat N-acetylglucosaminyltransferase I gene and regulatory role of its transcriptional diversity. Biosci Biotechnol Biochem 67 1515-1521
Fukayama M, Hino R and Uozaki H (2008) Epstein-Barr virus and gastric carcinoma: virus-host interactions leading to carcinoma. Cancer Science in press
Fukuda S, Kaga S, Sasaki H, Zhan L, Zhu L, Otani H, Kalfin R, K Das D and Maulik N (2004) Angiogenic signal triggered by ischemic stress induces myocardial repair in rat during chronic infarction. Journal of Molecular and Cellular Cardiology 36 547-559
Fukuhara N, Tagawa H, Kameoka Y, Kasugai Y, Karnan S, Kameoka J, Sasaki T, Morishima Y, Nakamura S and Seto M (2006) Characterization of target genes at the 2p15-16 amplicon in diffuse large B-cell lymphoma. Cancer Science 97 499-504
Fukui M, Imamura R, Umemura M, Kawabe T and Suda T (2003) Pathogen-associated molecular patterns sensitize macrophages to Fas ligand-induced apoptosis and IL-1beta release. Journal of Immunology 171 1868-1874
Fukui N, Ikeda Y, Ohnuki R, Hikita A, Tanaka S, Yamane S, Suzuki R, Sandell LJ and Ochi T (2006) Pro-inflammatory cytokine TNF-a induces BMP-2 in chondrocytes via mRNA stabilization and transcriptional up-regulation. Journal of Biological Chemistry281 27229-27241
Fukui T, Yoshiyama M, Hanatani A, Omura T, Yoshikawa J and Abe Y (2001) Expression of p22-phox and gp91-phox, essential components of NADPH oxidase, increases after myocardial infarction. Biochemical and Biophysical Research Communications 281 1200-1206
Fukuma K, Marubayashi S, Okada K, Yamada K, Kimura A and Dohi K (1999) Effect of lazaroid U-74389G and methylprednisolone on endotoxin-induced shock in mice. Surgery 125 421-430
Fukumoto S, Iwamoto T, Sakai E, Yuasa K, Fukumoto E, Yamada A, Hasegawa T, Nonaka K and Kato Y (2006) Current topics in pharmacological research on bone metabolism: osteoclast differentiation regulated by glycosphingolipids. Journal ofPharmacological Sciences 100 195-200
Fukushima T, Matsuzawa S, Kress CL, Bruey JM, Krajewska M, Lefebvre S, Zapata JM, ROnai Z and Reed JC (2007) Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses. Proceedings of the National Academy of Sciences USA104 6371-6376
Fukuyama M, Rokutan K, Sano T, Miyake H, Shimada M and Tashiro S (2005) Overexpression of a novel superoxide-producing enzyme, NADPH oxidase 1, in adenoma and well differentiated adenocarcinoma of the human colon. Cancer Letters 221 97-104
Fukuyama R, Ng KP, Cicek M, Kelleher C, Niculaita R, Casey G and Sizemore N (2007) Role of IKK and oscillatory NFkB kinetics in MMP-9 gene expression and chemoresistance to 5-fluorouracil in RKO colorectal cancer cells. Molecular Carcinogenesis 46 402-413
Fuller A, Yahikozawa H, So EY, Dal Canto M, Koh CS, Welsh CJ and Kim BS (2007) Castration of male C57L/J mice increases susceptibility and estrogen treatment restores resistance to Theiler’s virus-induced demyelinating disease. Journal ofNeuroscience Research 85 871-881
Fuly AL, Machado AL, Castro P, Abrahao A, Redner P, Lopes UG, Guimaraes JA and Koatz VL (2007) Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector. Toxicon 50 400-410
Fumimori T, Honda S, Migita K, Hamada M, Yoshimuta T, Honda J, Fukuda T, Suzuki R, Gotoh M, Eguchi K and Aizawa H (2004) Erythromycin suppresses the expression of cyclooxygenase-2 in rheumatoid synovial cells. Journal of Rheumatology 31 436-441
Funaki H, Shimizu K, Harada S, Tsuyama H, Fushida S, Tani T and Miwa K (2002) Essential role for nuclear factor kB in ischemic preconditioning for ischemia-reperfusion injury of the mouse liver. Transplantation 74 551-556
Funakoshi M, Sonoda Y, Tago K, Tominaga S and Kasahara T (2001) Differential involvement of p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase in the IL-1-mediated NF-kB and AP-1 activation. International Immunopharmacology 1 595-604
Funakoshi M, Tago K, Sonoda Y, Tominaga S and Kasahara T (2001) A MEK inhibitor, PD98059 enhances IL-1-induced NF-kB activation by the enhanced and sustained degradation of IkBa. Biochemical Biophysical Research Communications 283 248-254
Funaskoshi-Tago M, Shimizu T, Tago K, Nakamura M, Itoh H, Sonoda Y and Kasahara T (2008) Celecoxib potently inhibits TNFa-induced nuclear translocation and activation of NF-kB. Biochemical Pharmacology in press
Funakoshi-Tago M, Sonoda Y, Tanaka S, Hashimoto K, Tago K, Tominaga SI and Kasahara T (2003) TNF-induced NF-kB activation is impaired in focal adhesion kinase (FAK)-deficient fibroblasts. Journal of Biological Chemistry 278 29359-29365
Funakoshi-Tago M, Tago K, Andoh K, Sonoda Y, Tominaga S and Kasahara T (2005) Functional role of c-Src in IL-1-induced NF-kB activation: c-Src is a component of the IKK complex. Journal of Biochemistry (Tokyo) 137 189-197
Funakoshi-Tago M, Tago K, Hayakawa M, Tominaga SI, Ohshio T, Sonoda Y and Kasahara T (2008) TRAF6 is a critical signal transducer in IL-33 signaling pathway. Cellular Signaling in press
Funakoshi-Tago M, Tago K, Sonoda Y, Tominaga S, Kasahara T (2003) TRAF6 and c-SRC induce synergistic AP-1 activation via PI3-kinase-AKT-JNK pathway. European Journal of Biochemistry 270 1257-1268
Funami K, Matsumoto M, Oshiumi H, Akazawa T, Yamamoto A and Seya T (2004) The cytoplasmic ‘linker region’ in Toll-like receptor 3 controls receptor localization and signaling. International Immunology 16 1143-1154
Funami K, Sasai M, Ohba Y, Oshiumi H, Seya T and Matsumoto M (2007) Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA. Journal of Immunology 179 6867-6872
Funami K, Sasai M, Oshiumi H, Seya T and Matsumoto M (2008) Homo-oligomerization is essential for Toll/IL-1 receptor domain-containing adaptor molecule-1-mediated NF-kB and IRF-3 activation. Journal of Biological Chemistry 283 18283-18291
Funderburg N, Lederman MM, Feng Z, Drage MG, Jadlowsky J, Harding CV, Weinberg A and Sieg SF (2007) Human beta-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2. Proceedings of the National Academy of Sciences USA 104 18631-18635
Funk JL, Frye JB, Oyarzo JN, Kuscuoglu N, Wilson J, McCaffrey G, Stafford G, Chen G, Lantz RC, Jolaad SD, Solyom AM, Kiela PR and Timmermann BN (2006) Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis.Arthritis and Rheumatism 54 3452-3464
Funkhouser AW, Kang JA, Tan A, Li J, Zhou L, Abe MK, Solway J and Hershenson MB (2004) Rhinovirus 16 3C protease induces IL-8 and granulocyte-macrophage colony-stimulating factor expression in human bronchial epithelial cells. Pediatric Research 55 13-18
Furia B, Deng L, Wu K, Baylor S, Kehn K, Li H, Donnelly R, Coleman T and Kashanchi F (2002) Enhancement of nuclear factor-kB acetylation by coactivator p300 and HIV-1 Tat proteins. Journal of Biological Chemistry 277 4973-4980
Furihata T, Hosokawa M, Satoh T and Chiba K (2004) Synergistic role of specificity proteins and upstream stimulatory factor 1 in transactivation of the mouse carboxylesterase 2/microsomal acylcarnitine hydrolase gene promoter. Biochemistry Journal 384 101-110
Furman RR, Asgary Z, Mascarenhas JO, Liou HC and Schattner EJ (2000) Modulation of NF-kB activity and apoptosis in chronic lymphocytic leukemia B cells. Journal of Immunology 164 2200-2206
Furst R, Blumenthal SB, Kiemer AK, Zahler S and Vollmar AM (2006) NF-kB-independent anti-inflammatory action of salicylate in human endothelial cells: induction of heme oxygenase-1 by the JNK/AP-1 pathway. Journal of Pharmacology and ExperimentalTherapeutics 318 389-394
Furst R, Schroeder T, Eilken HM, Bubik MF, Kiemer Ak, Zahler S and Vollmar AM (2006) MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium. FASEB Journal in press
Furukawa S, Matsubara R and Ichyama T (2008) Regulation of proinflammatory cytokine cascade in Kawasaki disease [Article in Japanese]. Nippon Risho 66 258-264
Furumoto Y, Nunomura S, Terada T, Rivera J and Ra C (2004) The Fcepsilon RIbeta ITAM exerts inhibitory control on MAP kinase and IkB kinase phosphorylation and mast cell cytokine production. Journal of Biological Chemistry 279 49177-49187
Furuno T and Nakanishi M (2006) Neurotrophic factors increase tumor necrosis factor-alpha-induced nuclear translocation of NF-kB in rat PC12 cells. Neuroscience Letters 392 240-242
Furusu A, Nakayama K, Xu Q, Konta T and Kitamura M (2007) MAP kinase-dependent, NF-kB-independent regulation of inhibitor of apoptosis protein genes by TNF-a. Journal of Cellular Physiology210 703-710
Furusu A, Nakayama K, Xu Q, Konta T, Sugiyama H and Kitamura M (2001) Expression, regulation, and function of inhibitor of apoptosis family genes in rat mesangial cells. Kidney International 60 579-586
Furuya K, Ozaki T, Hanamoto T, Hosoda M, Hayashi S, Barker PA, Takano K, Matsumoto M and Nakagawara A (2007) Stabilization of p73 by nuclear IKK-a mediates cisplatin-induced apoptosis.Journal of Biological Chemistry 282 18365-18378
Furuya T, Hakoda M, Ichikawa N, Higami K, Nanke Y, Yago T, Kamatani N and Kotake S (2007) Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid arthritis.Clinical Rheumatology 26 2137-2141
Fusco AJ, Savinova OV, Talwar R, Kearns JD, Hoffmann A and Ghosh G (2008) Stabililzation of RelB requires multi-domain interactions with p100/p52. Journal of Biological Chemistry in press
Fusco F, Bardaro T, Fimiani G, Mercadante V, Miano MG, Falco G, Israel A, Courtois G, D’Urso M and Ursini MV (2004) Molecular analysis of the genetic defect in a large cohort of IP patients and identification of novel NEMO mutations interfering with NF-kB activation. Human Molecular Genetics 13 1763-1773
Fusco F, Mercadante V, Miano MG and Ursini MV (2006) Multiple regulatory regions and tissue-specific transcription initiation mediate the expression of NEMO/IKKg gene. Gene 383 99-107
Fusco F, Pescatore A, Bal E, Ghoul A, Paciolla M, Kioi MB, C’Urso M, Rabia SH, Bodemer C, Bonnefont JP, Munnich A, Miano MG, Smahi A and Ursini MV (2008) Alterations of the IKBKG locus and diseases: an update and a report of 13 novel mutations. Human Mutations in press
Fuseler JW, Merrill DM, Rogers JA, Grisham MB and Wolf RE (2006) Analysis and quantitation of NF-kB nuclear translocation in tumor necrosis factor alpha (TNF-alpha) activated vascular endothelial cells. Microscopy and Microanalysis 12 269-276
Fusuma EE, Caruso SC, Lopez DF, Costa LJ, Janini LM, De Mendonca JS, Kallaas EG and Diaz RS (2005) Duplication of peri-kB and NF-kB sites of the first human immunodeficiency virus type 2 (HIV-2) transmission in Brazil. AIDS Research and Human Retroviruses21 965-970
Futakuchi M, Ogawa K, Tamano S, Takahashi S and Shirai T (2004) Suppression of metastasis by nuclear factor kB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. Cancer Science 95 18-24
Fyfe M, Bergstrom M, Aspengren S and Peterson A (2005) PAR-2 activation in intestinal epithelial cells potentiates interleukin-1beta-induced chemokine secretion via MAP kinase signaling pathways. Cytokine 31 358-367
