References – B
Baba M (2004) Inhibitors of HIV-1 gene expression and transcription. Current Topics in Medicinal Chemistry 4 871-882
Baba M (2006) Recent status of HIV-1 gene expression inhibitors. Antiviral Research 71 301-306
Baba T, Mimura J, Gradin K, Kuroiwa A, Watanabe T, Matsuda Y, Inazawa J, Sogawa K and Fujii-Kuriyama Y (2001) Structure and expression of the Ah receptor repressor gene. Journal of Biological Chemistry 276 33101-33110
Baba TW, Giroir BP and Humphries EH (1985) Cell lines derived from avian lymphomas exhibit two distinct phenotypes. Virology 144 139-151
Baba Y, Nishida K, Fujii Y, Hirano T, Hikida M and Kurosaki T (2007) Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses. Nature Immunology in press
Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WU, Semenkovich CF, Fazio S and Linton MF (2007) Macrophage expression of peroxisome proliferator activated receptor-a reduces atherosclerosis in low-density lipoprotein receptor deficient mice. Circulation in press
Babakov VN, Petukhova OA, Turoverova LV, Kropacheva IV, Tentler DG, Bolshakova AV, Podolskaya EP, Magnusson KE and Pinaev GP (2008) RelA/NF-kB transcription factor associates with alpha-actinin-4. Experimental Cell Research in press
Babbar N, Hacker A, Huang Y and Casero Jr RA (2006) Tumor necrosis factor alpha induces spermidine/spermine N1-acetyltransferase through nuclear factor kB in non-small cell lung cancer cells. Journal of Biological Chemistry 281 24182-24192
Babcock TA, Helton WS, Anwar KN, Zhao YY and Espat N (2004) Synergistic anti-inflammatory activity of omega-3 lipid and rofecoxib pretreatment on macrophage proinflammatory cytokine production occurs via divergent NF-kB activation. JPEN J Parenter Enteral Nutr 28 232-239
Babu D, Lee JS, Park SY, Thapa D, Choi MK, Kim AR, Park YJ and Kim JA (2008) Involvement of NF-kB in the inhibitory actions of Platycarya strobilacea on the TNF-a-induced monocyte adhesion to colon epithelial cells and chemokine expression. Archives of Pharmacy Research 31 727-735
Babu G, Waterfield M, Chang M, Wu X and Sun S-C (2006) Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells. Journal of Biological Chemistry 281 14041-14047
Babu RJ, Chatterjee A and Singh M (2004) Assessment of skin irritation and molecular responses in rat skin exposed to nonane, dodecane and tetradecane. Toxicology Letters 153 255-266
Baby J, Pickering BF, Vashisht Gopal YN and Van Dyke MW (2007) Constitutive and inducible nuclear factor-kB in immortalized normal human bronchial epithelial and non-small cell lung cancer cell lines. Cancer Letters in press
Baccam M and Bishop GA (1999) Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kB-independent IL-6 production in B cells. European Journal of Immunology 29 3855-3866
Baccam M, Woo SY, Vinson C and Bishop GA (2003) CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kB, AP-1, and C/EBP. Journal of Immunology 170 3099-3108
Bach JH, Chae HS, Rah JC, Lee MW, Park CH, Choi SH, Choi JK, Lee SH, Kim YS, Kim KY, Lee WB, Suh YH and Kim SS (2001) C-terminal fragment of amyloid precursor protein induces astrocytosis. Journal of Neurochemistry 78 109-120
Bachelerie F, Alcami J, Arenzana-Seisdedos F and Virelizier J-L (1991) HIV enhancer activity perpetuated by NF-kB induction on infection of monocytes. Nature 350 709-712
Bachar O, Adner M, Uddman R and Cardell LO (2004) Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappaB signaling pathways. European Journal of Immunology 34 1196-1207
Bacher S, Grosshans J, Droge W and Schmitz ML (2001) The Drosophila proteins Pelle and Tube induce JNK/AP-1 activity in mammalian cells. FEBS Letters 497 153-158
Bacher S and Schmitz ML (2004) The NF-kB pathway as a potential target for autoimmune disease therapy. Current Pharm Des 10 2827-2837
Bachevalier F, Marchal C, Di Cesare MP, Antunes A and Truchetet F (2003) Lethal neurological involvement during incontinentia pigmenti [Article in French]. Ann Dermatol Venereol 130 1139-1142
Bachmann M, Horn K, Poleganov MA, Paulukat J, Nold M, Pfeilschifter J and Muhl H (2006) Interleukin-18 secretion and Th1-like cytokine responses in human peripheral blood mononuclear cells under the influence of the toll-like receptor-5 ligand flagellin. Cellular Microbiology 8 289-300
Bachmeier BE, Mohrenz IV, Mirisola V, Schleicher E, Romeo F, Hohneke C, Jochum M, Nerlich AG and Pfeffer U (2007) Curcumin down-regulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkB. Carcinogenesis in press
Bachmeier BE, Vene R, Iancu CM, Pfeffer U, Mayer B, Noonan D, Albini A, Jochum M and Nerlich AG (2005) Transcriptional control of cell density dependent regulation of matrix metalloproteinase and TIMP expression in breast cancer cell lines. Thrombosis and Haemostosis 93 761-769
Bachmeier K, Toya S, Gao X, Triantafillou T, Garrean S, Park GY, Frey RS, Vogel S, Minshall R, Christman JW, Tiruppathi C and Malik AB (2007) E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury.Nature Medicine in press
Bachmeyer C, Mak CH, Yu CY and Wu LC (1999) Regulation by phosphorylation of the zinc finger protein KRC that binds the kB motif and V(D)J recombination signal sequences [published erratum appears in Nucleic Acids Research 1999 Nov 15;27(22):following 4531]. Nucleic Acids Research 27 643-648
Backhed F, Normark S and Richter-Dahlfors A (2002) TLR4-dependent lipopolysaccharide signalling in epithelial cells is independent of extracellular protease activity. Cellular Microbiology 4 297-303
Bachrach E, Dreja H, Lin YL, Mettling C, Pinet V, Corbeau P and Piechaczyk M (2005) Effects of virion surface gp120 density on infection by HIV-1 and viral production by infected cells. Virology 332 418-429
Back M, Bu DX, Branstrom R, Sheikine Y, Yan ZQ and Hansson GK (2005) Leukotriene B4 signaling through NF-kB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia. Proceedings of the National Academy of Sciences USA in press
Bacot SM, Lenz P, Frazier-Jessen MR and Feldman GM (2003) Activation by prion peptide PrP(106-126) induces a NF-kB-driven proinflammatory response in human monocyte-derived dendritic cells. Journal of Leukocyte Biology 74 118-125
Badgwell B, Parihar R, Magro C, Dierksheide J, Russo T and Carson WE 3rd (2002) Natural killer cells contribute to the lethality of a murine model of Escherichia coli infection. Surgery 132 205-212
Badou A, Bennasser Y, Moreau M, Leclerc C, Benkirane M and Bahraoui E (2000) Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway. Journal of Virology 74 10551-10562
Badr G, Borhis G, Lefevre EA, Chaoul N, Deshayes F, Dessirier V, Lapree G, Tsapis A and Richard Y (2008) BAFF enhances chemotaxis of primary human B cells. A particular synergy between BAFF and CXCL13 on memory B cells. Blood in press
Badr G, Borhis G, Treton D and Richard Y (2005) IFN{alpha} enhances human B-cell chemotaxis by modulating ligand-induced chemokine receptor signaling and internalization. International Immunology 17 459-467
Badran BM, Kunstman K, Stanton J, Moschitta M, Zerghe A, Akl H, Burny A, Wolinsky SM and Willard-Gallo KE (2005) Transcriptional regulation of the human CD3gamma gene: the TATA-less CD3gamma promoter functions via an initiator and contiguous Sp-binding elements. Journal of Immunology 174 6238-6249
Badrichani AZ, Stroka DM, Bilbao G, Curiel DT, Bach FH and Ferran C (1999) Bcl-2 and Bcl-XL serve an anti-inflammatory function in entohelial cells through inhibition of NF-kB. Journal of Clinical Investigation 103 543-553
Bae EA, Kim EJ, Park JS, Kim HS, Ryu JH and Kim DH (2006) Ginsenosides Rg3 and Rh2 inhibit the activation of AP-1 and protein kinase A pathway in lipopolysaccharide/interferon-g-stimulated BV-2 microglial cells. Planta Medica in press
Bae EM, Kim WJ, Suk K, Kang YM, Park JE, Kim WY, Choi EM, Choi BK, Kwon BS and Lee WH (20070 Reverse signaling initiated from GITRL induces NF-kB activation through ERK in the inflammatory activation of macrophages. Molecular Immunology in press
Bae IK, Min HY, Han AR, Seo EK and Lee SK (2005) Suppression of lipopolysaccharide-induced expression of inducible nitric oxide synthase by brazilin in RAW 264.7 macrophage cells. European Journal of Pharmacology 513 237-242
Bae JS, Jang MK, Hong S, An WG, Choi YH, Kim HD and Cheong J (2003) Phosphorylation of NF-kB by calmodulin-dependent kinase IV activates anti-apoptotic gene expression. Biochemical and Biophysical Research Communications 305 1094-1098
Bae MK, Kim SR, Lee HJ, Wee HJ, Yoo MA, Ock Oh S, Baek SY, Kim BS, Kim JB, Sik-Yoon and Bae SK (2006) Aspirin-induced blockade of NF-kappaB activity restrains up-regulation of glial fibrillary acidic protein in human astroglial cells.
Biochimica et Biophysica Acta 1763 282-289
Baek SH, Lim JH, Park DW, Kim SY, Lee YH, Kim JR and Kim JH (2001) Group IIA secretory phospholipase A(2) stimulates inducible nitric oxide synthase expression via ERK and NF-kB in macrophages. European Journal of Immunology 31 2709-2717
Baek SH, Ohgi KA, Rose DW, Koo EH and Glass CK (2002) Exchange of N-CoR corepressors and Tip60 coactivator complexes links gene expression by NF-kB and b-amyloid precursor protein. Cell 110 55-67
Bae SY, Yim JH, Lee HK and Pyo S (2005) Activation of murine peritoneal macrophages by sulfated exopolysaccharide from marine microalga Gyrodinium impudicum (strain KG03): Involvement of the NF-kB and JNK pathway. InternationalImmunopharmacology 6 473-484
Baens M, Fevery S, Sagaert X, Noels H, Hagens S, Broeckx V, Billau AD, De Wolf-Peeters C and Marynen P (2006) Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkB Kinase gamma polyubiquitination. Cancer Research 66 5270-5277
Baens M, Noels H, Broeckx V, Hagens S, Fevery S, Billiau AD, Vankelecom H and Marynen P (2006) The dark side of EGFP: defective polyubiquitination. PLoS ONE 1e54
Baer JT, Du Laney TV, Wyrick PB, McCain AS, Fischer TA, Merricks EP, Baldwin AS and Nichols TC (2003) Nuclear Factor-kB activation in endothelium by Chlamydia pneumoniae without active infection. Journal of Infectious Disease 188 1094-1097
Baer M, Dillner A, Schwartz RC, Sedon C, Nedospasov S and Johnson PF (1998) Tumor necrosis factor a transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kB p50. Molecular and Cellular Biology 18 5678-5689
Baer-Dubowska W (2006) Cancer chemopreventive agents-drugs for the 21st century? Acta Poloniae Pharmaceutica 63 369-373
Baetas-Da-Cruz W, Castro P, Guimaraes EV, Koatz VL, Corte-Real S and Calalcante LA (2007) Increase in nuclear translocation of nuclear transcription factor-kB following infection of a human Schwann cell line with Leishmania amazonensis. British Journal of Dermatology in press
Baetz A, Frey M, Heeg K and Dalpke AH (2004) Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells. Journal of Biological Chemistry 279 54708-54715
Baetz D, Reula KM, Ens K, Shaw J, Kothari S, Yurkova N and Kirshenbaum LA (2005) Nuclear factor-kB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes. Circulation 1123777-3785
Baeuerle PA (1991) The inducible transcription activator NF-kB:regulation by distinct protein subunits. Biochimica et Biophysica Acta 1072 63-80
Baeuerle PA (1998) IkB-NF-kB structures: at the interface of inflammation control. Cell 95 729-731
Baeuerle PA and Baltimore D (1988) Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kB transcription factor. Cell 53 211-217
Baeuerle PA and Baltimore D (1988) IkB: a specific inhibitor of the NF-kB transcription factor. Science 242 540-546
Baeuerle PA and Baltimore D (1989) A 65-kD subunit of active NF-kB is required for inhibition of NF-kB by IkB. Genes & Development 3 1689-1698
Baeuerle PA and Baltimore D (1991) The physiology of the NF-kB transcription factor. Molecular Aspects of Cellullar Regulation 6 409-432
Baeuerle PA and Baltimore D (1996) NF-kB: ten years after. Cell 87 13-20
Baeuerle PA and Henkel T (1994) Function and activation of NF-kB in the immune system. Annual Review of Immunology 12 141-179
Baeza-Raja B and Munoz-Canoves P (2004) p38 MAPK-induced NF-kB activity is required for skeletal muscle differentiation: role of IL-6. Molecular Biology of the Cell 15 2013-2026
Bafica A, Scanga CA, Equils O and Sher A (2004) The induction of Toll-like receptor tolerance enhances rather than suppresses HIV-1 gene expression in transgenic mice. Journal of Leukocyte Biology 75 460-466
Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C and Hellman J (2007) MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. Journal of Immunology 178 1164-1171
Bagchi D, Sen CK, Bagchi M and Atalay M (2004) Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Moscow) 69 75-80
Baghdiguian S, Martin M, Richard I, Pons F, Astier C, Bourg N, Hay RT, Chemaly R, Halaby G, Loiselet J, Anderson LV, Lopez de Munain A, Fardeau M, Mangeat P, Beckmann JS and Lefranc G (1999) Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkB alpha/NF-kB pathway in limb-girdle muscular dystrophy type 2A [published erratum appears in Nat Med 1999 Jul;5(7):849]. Nature Medicine 5 503-511
Bagneris C, Ageichik AV, Cronin N, Wallace B, Collins M, Boshoff C, Waksman G and Barrett T (2008) Crystal structure of a vFlip-IKKg complex: insights into viral activation of the IKK signalosome. Molecular Cell 30 620-631
Baguley BC and Marshall E (2005) Do negative feedback oscillations drive variations in the length of the tumor cell division cycle? Oncology Research 15291-294
Bahrun U, Kimoto M, Tsukamoto H, Tsuneyoshi N, Kohara J and Fukudome K (2007) Preparation and characterization of agonistic monoclonal antibodies against Toll-like receptor 4-MD-2 complex. Hybridoma (Larchmont) 26 393-400
Bai A, Guo Y and Lu N (2007) The effect of the cholinergic anti-inflammatory pathway on experimental colitis. Scandinavian Journal of Immunology 66 538-545
Bai AP, Ouyang Q, Gan HT and Wang CH (2004) Activation of nuclear factor-kB and expression of cytokine in intestinal epithelia stimulated by TNF-alpha [Article in Chinese]. Sichuan Da Xue Xue Bao Yi Xue Ban 35 778-780
Bai AP, Ouyang Q and Hu RW (2005) Diallyl trisulfide inhibits tumor necrosis factor-alpha expression in inflammed mucosa of ulcerative colitis. Dig Dis Sci50 1426-1431
Bai AP, Ouyang Q, Xiao XR and Li SF (2006) Probiotics modulate inflammatory cytokine secretion from inflamed mucosa in active ulcerative colitis.International Journal of Clinical Practice 60 284-288
Bai AP, Ouyang Q, Zhang W, Wang CH and Li SF (2004) Probiotics inhibit TNF-alpha-induced interleukin-8 secretion of HT29 cells. World Journal of Gastroenterology 10 455-457
Bai J and Cederbaum AI (2000) Overexpression of catalase in mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to TNF-alpha induced apoptosis. Journal of Biological Chemistry 275 19241-19249
Bai L, Zhang Z< Zhang H, Li X, Yu Q, Lin H and Yang W (2008) HIV-1 Tat protein alter the tight junction integrity and function of retinal pigment epithelium: an in vitro study. BMC Infectious Diseases in press
Bai M, Papoudou-Bai A, Kitsoulis P, Horianopoulos N, Kamina S, Agnantis NJ and Kanavaros P (2005) Cell cycle and apoptosis deregulation in classical Hodgkin lymphomas. In Vivo 19 439-453
Bai M, Tsanou E, Agnantis NJ, Kamina S, Grepi C, Stefanaki K, Rontogianni D, Galani V and Kanavaros P (2004) Proliferation profile of classical Hodgkin’s lymphomas. Increased expression of the protein cyclin D2 in Hodgkin’s and Reed-Sternberg cells. Modern Pathology 17 1338-1345
Bai S, Kitaura H, Zhao H, CHen J, Muller JM, Schule R, Darnay B, Novack DV, Ross FP and Teitelbaum SL (2005) FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner. Journal of Clinical Investigation 115 2742-1751
Bai S, Liu H, Chen KH, Eksarko P, Perlman H, Moore TL and Pope RM (2004) NF-kB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis. Arthritis Rheum 50 3844-3855
Bai SK, Lee SJ, Na HJ, Ha KS, Han JA< Lee H, Kwon YG, Chung CK and Kim YM (2005) b-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macrophages by suppressing redox-based NF-kB activation. Experimental and Molecular Medicine 37 323-334
Bai X, Lu D, Bai J, Zheng H, Ke Z, Li X and Luo S (2004) Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kB. Biochemical and Biophysical Research Communications 314 197-207
Bai XC, Lu D, Liu AL, Zhang ZM, Li XM, Zou ZP, Zeng WS, Cheng BL and Luo SQ (2005) Reactive oxygen species stimulates receptor activator of NF-kB ligand expression in osteoblast. Journal of Biological Chemistry 280 17497-17506
Bai XJ, Li B, Wang HP, Tang ZH and Li SQ (2007) Primary investigaion of the relationship between glucocorticoid induced leucine zipper and inflammatory reaction [Article in Chinese]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 19 7-10
Bai Y, Ge Q, Liu Q, Li T, Wang J and Lu Z (2006) Evaluating the binding affinities of NF-kB protein to the single-nucleotide mismatch DNA binding sites by using double-stranded DNA microarray. J Nanosci Nanotechnol 6 1014-1018
Bai Y, Ge Q, Wang J, Li T, Liu Q and Lu Z (2005) Optimization of on-chip elongation for fabricating double-stranded DNA microarrays. Colloids Surf B Biointerfaces 40 153-158
Bai Y and Hart RP (1998) Cultured sympathetic neurons express functional interleukin-1 receptors. Journal of Neuroimmunology 91 43-54
Bai Y, Li Q< Yang J, Zhou X, Yin X and Zhao D (2008) p75(NTR) activation of NF-kB is involved in PrP106-126-induced apoptosis in mouse neuroblastoma cells. Neurosciences Research in press
Bai Y, Onuma H, Bai X, Medvedev AV, Misukonis M, Weinberg JB, Cao W, Robidoux J, Floering LM, Daniel KW and Collins S (2005) Persistent NF-kB activation in Ucp2-/-mice leads to enhanced nitric oxide and inflammatory cytokine production. Journal of Biological Chemistry 280 19062-19069
Bai YD, Yang FS, Xuan K, Bai YX and Wu BL (2008) Inhibition of RANK/RANKL signal transduction pathway: a promising approach for osteoporosis treatment. Medical Hypotheses in press
Bai YP, Liu YH, Chen J, Song T, You Y, Tang ZY, Li YJ and Zhang GG (2007) Rosiglitazone attenuates NF-kB-dependent ICAM-1 and TNF-a production caused by homocysteine via inhibiting ERK(1/2)/p38MAPK activation. Biochemical andBiophysical Research Communications in press
Baichwal VR and Baeuerle PA (1997) Apoptosis: activate NF-kB or die? Current Biology 7 R94-R96
Baier PK, Hempel S, Waldvogel B and Baumgartner U (2006) Zonation of hepatic bile salt transporters. Dig Dis Sci 51 587-593
Baigent SJ, Zhang G, Fray MD, Flick-Smith H, Goodbourn S and McCauley JW (2002) Inhibition of beta interferon transcription by noncytopathogenic bovine viral diarrhea virus is through an interferon regulatory factor 3-dependent mechanism. Journal of Virology 76 8979-8988
Baik JE, Ryu YH, Han JY, Im J, Kum KY, Yun CH, Lee K and Han SH (2008) Lipoteichoic acid partially contributes to the inflammatory responses to Enterococcus faecalis. Journal of Endodology 34 975-982
Baines DL, Janes M, Newman DJ and Best OG (2002) Oxygen-evoked changes in transcriptional activity of the 5′-flanking region of the human amiloride-sensitive sodium channel (alphaENaC) gene: role of nuclear factor kB. Biochemistry Journal 364 537-545
Baird SD, Lewis SM, Turcotte M and Holcik M (2007) A search for structurally similar cellular internal ribosome entry sites.
Nucleic Acids Research in press
Bairead E, Harmon DL, Curtis AM, Kelly Y, O’Leary C, Gardner M, Leahy DT, Vaughan P, Keegan D, O’Morain C, O’Donoghue D, Shanahan F, Parfrey NA and Quane KA (2003) Association of NOD2 with Crohn’s Disease in a homogenous Irish population. European Journal of Human Genetics 11 237-244
Baixeras E, Jeay S, Kelly PA and Postel-Vinay MC (2001) The proliferative and antiapoptotic actions of growth hormone and insulin-like growth factor-1 are mediated through distinct signaling pathways in the Pro-B Ba/F3 cell line. Endocrinology 142 2968-2977
Bajenova O, Tang B, Pearse R, Feinman R, Childs BH and Michaeli J (2004) RIP kinase is involved in arsenic-induced apoptosis in multiple myeloma cells. Apoptosis 9 561-571
Bajova H, Nelson TE and Gruol DL (2008) Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kB in hippocampal neuronal cell culture. Journal of Neuroimmunology in press
Bajwa A, Shenassa BB, Human L, Ghoniem GM and Abdel-Mageed AB (2004) NF-kB-dependent gene expression of proinflammatory cytokines in T24 cells: possible role in interstitial cystitis. Urology Research in press
Bak SP, Amiel E, Walters JJ and Berwin B (2007) Calreticulin requires an ancillary adjuvant for the induction of efficient cytotoxic T cell responses.Molecular Immunology in press
Bakalkin G, Yakovleva T and Terenius L (1994) Prodynorphin gene expression relates to NF-kB factors. Brain Research Molecular Brain Research 24 301-312
Bakalkin GY, Yakovleva T and Terenius L (1993) NF-kB-like factors in the murine brain. Developmentally-regulated and tissue-specific expression. Molecular Brain Research 20 137-146
Baker MS, Chen X, Cao XC and Kaufman DB (2001) Expression of a dominant negative inhibitor of NF-kB protects MIN6 beta-cells from cytokine-induced apoptosis. Journal of Surgical Research 97 117-122
Baker MS, Chen X, Rotramel A, Nelson J and Kaufman DB (2003) Proinflammatory cytokines induce NF-kB-dependent/NO-independent chemokine gene expression in MIN6 beta cells. Journal of Surgical Research 110 295-303
Baker SJ and Reddy EP (1996) Transducers of life and death: TNF receptor superfamily and associated proteins. Oncogene 12 1-9
Baker SJ and Reddy EP (1998) Modulation of life and death by the TNF receptor superfamily. Oncogene 17 3261-3270
Bakkar N, Wang J, Ladner KJ, Wang H, Dahlman JM, Carathers M, Acharyya S, Rudnicki MA, Hollenbach AD and Guttridge DC (2008) IKK/NF-kB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis. Journal of Cell Biology 180 787-802
Bakker RA, Schoonus SB, Smit MJ, Timmerman H and Leurs R (2001) Histamine H(1)-receptor activation of nuclear factor-kB: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling. Molecular Pharmacology 60 1133-1142
Bakker RA, Weiner DM, Ter Laak T, Beuming T, Zuiderveld OP, Edelbroek M, Hacksell U, Timmerman H, Brann MR and Leurs R (2004) 8R-lisuride is a potent stereospecific histamine H1-receptor partial agonist. Molecular Pharmacology 65 538-549
Bakker TR, Reed D, Renno T and Jongeneel CV (1999) Efficient adenoviral transfer of NF-kB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis. International Journal of Cancer 80 320-323
Bakker TR, Renno T and Jongeneel CV (1999) Impaired fetal thymocyte development after efficient adenovirus-mediated inhibition of NF-kB activation. Journal of Immunology 162 3456-3462
Bakkum-Gamez JN, Aletti G, Lewis KA, Keeney GL, Thomas BM, Navarro-Teulon I and Cliby WZ (2008) Müllerian inhibiting substance type II receptor (MISIIR): a novel, tissue-specific target expressed by gynecologic cancers. Gynecology and Oncology 108 141-148
Balachandran P, Pugh ND, Ma G and Pasco DS (2006) Toll-like receptor 2-dependent activation of monocytes by Spirulina polysaccharide and its immune enhancing action in mice. International Immunopharmacology 6 1808-1814
Balaci L, Spada MC, Olla N, SOle G, Loddo L, Andedda F, Naitza S, Zuncheddu MA, Maschio A, Altea D, Uda M, PIlia S, Sanna S, Masala M, Crisponi L, Fattori M, Devoto M, DOratiotto S, Rassu S, Mereu S, Giua E, Cadeddu NG, Atzeni R, Pelosi U, Corrias A, Perra R, Torrazza PL, Pirina P, Ginesu F, Marcias S, Schintu MG, Giacco GS, Manconi PE, Malerba G, Bisognin A, Trabetti E, Boner A, Pescollderungg L, Pignatti PF, Schlessinger D, Cao A and Pilia G (2007) IRAK-M is involved in the pathogenesis of early-onset persistent asthma. AmericanJournal of Human Genetics 80 1103-1114
Balaram SK, Agrawal DK and Edwards JD (1999) Insulin like growth factor-1 activates Nuclear Factor-kB and increases transcription of the intercellular adhesion molecule-1 gene in endothelial cells. Cardiovascular Surgery 7 91-97
Balasenthil S, Sahin AA, Barnes CJ, Wang RA, Pestell RG, Vadlamudi RK and Kumar R (2004) P21-activated kinase-1 signaling mediates cyclin D1 expression in mammary epithelial and cancer cells. Journal of Biological Chemistry 279 1422-1428
Balasubramanian A, Munshi N, Koziel MJ, Hu Z, Liang TJ, Groopman JE and Ganju RK (2005) Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells. Journal of General Virology 86 3291-3301
Balazs R (2006) Trophic effect of glutamate. Current Topics in Medicinal Chemistry 6 961-968
Balcavage WX, Baxter-Gabbard KL, Ko M, Rea M, Padgett F and Levine AS (1972) Mitochondrial alterations associated with avian reticuloendotheliosis virus (strain T) pathogenicity. Biochemical and Biophysical Research Communications 48 605-611
Baldassarre F, Mallardo M, Mezza M, Mezza E, Scala G and Quinto I (1995) Regulation of NF-kB through the nuclear processing of p105 (NF-kB1) in Epstein-Barr virus-immortalized B cell lines. Journal of Biological Chemistry 270 31244-31248
Baldi L, Brown K, Franzoso G and Siebenlist U (1996) Critical role for lysines 21 and 22 in signal-induced ubiquitin-mediated proteolysis of IkB-a. Journal of Biological Chemistry 271 376-379
Baldus S and Meinertz T (2006) Current concepts of diabetic atherogenesis [Article in German]. Clinical Research in Cardiology 95 i1-i6
Baldwin AS (2001) Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB. Journal of Clinical Investigation 107 241-246
Baldwin Jr AS (2001) Series introduction: the transcription factor NF-kB and human disease. Journal of Clinical Investigation 107 3-6
Baldwin Jr AS (1994) Title? In, Transcription: Mechanisms and Regulation, eds RC Conaway and JW Conaway, pp 443-457
Baldwin Jr AS (1996) The NF-kB and IkB proteins: new discoveries and insights. Annual Review of Immunology 14 649-681
Baldwin Jr AS (2001) Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB. Journal of Clinical Investigation 107 241-246
Baldwin Jr AS (2001) Series introduction: the transcription factor NF-kB and human disease. Journal of Clinical Investigation 107 3-6
Baldwin AS (2004) NFkB: Biology and Pathology – Keystone Symposium. IDrugs 7 215-216
Baldwin Jr AS and Sharp PA (1989) Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I histocompatibility gene. Molecular and Cellular Biology 7 305-313
Baldwin Jr AS, Azizkhan JC, Jensen DE, Beg AA and Coodly LR (1991) Induction of NF-kB DNA-binding activity during the Go-to-G1 transition in mouse fibroblasts. Molecular and Cellular Biology 11 4943-4951
Baldwin Jr AS, LeClair KP, Singh H and Sharp PA (1990) A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and k immunoglobulin genes. Molecular and Cellular Biology 10 1406-1414
Bales KR, Du Y, Dodel RC, Yan G-M, Hamilton-Byrd E and Paul SM (1998) The NF-kB/Rel family of proteins mediates Ab-induced neurotoxicity and glial activation. Molecular Brain Research 57 63-72
Balkwill F and Coussens LM (2004) Cancer: an inflammatory link. Nature 431 405-406
Balla A, Toth B, Timar G, Bak J and Krajcsi P (2001) Molecular targets for pharmacological cytoprotection. Biochem Pharmacol 61 769-777
Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR and Greene WC (1989) Activation of the interleukin-2 receptor a gene: regulatory role for DNA-protein interactions flanking the kB enhancer. New Biologist 1 83-92
Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR and Greene WC (1988) HTLV-I Tax induces cellular proteins that activate the kB element in the IL-2 receptor gene. Science 241 1652-1655
Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B and Greene WC (1992) The 65-kD subunit of human NF-kB functions as a potent transcriptional activator and a target for v-Rel mediated repression. Proceedings of the National Academy of Sciences USA 89 1875-1879
Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M and Greene WC (1990) The v-rel oncogene encodes a kB enhancer binding protein that inhibits NF-kB function. Cell 63 803-814
Ballard-Croft C and Horton JW (2002) Sympathoadrenal modulation of stress-activated signaling in burn trauma. J Burn Care Rehabil 23 172-182
Ballard-Croft C, Maass DL, Sikes P, White J and Horton J (2002) Activation of stress-responsive pathways by the sympathetic nervous system in burn trauma. Shock 18 38-45
Balliet AG, Hollander MC, Fornace AJ Jr, Hoffman B and Liebermann DA (2003) Comparative analysis of the genetic structure and chromosomal mapping of the murine Gadd45g/CR6 gene. DNA Cell Biology 22 457-468
Balmelli C, Alves MP, Steiner E, Zingg D, Peduto N, Ruggli N, Gerber H, McCullough K and Summerfield A (2008) Responsiveness of fibrocytes to toll-like receptor danger signals. Immunobiology 212 693-699
Balogh P, Balazs M, Czompoly T, Weih DS, Arnold HH and Weih F (2007) Distinct roles of lymphotoxin-beta signaling and the homeodomain transcription factor Nkx2.3 in the ontogeny of endothelial compartments in spleen. Cell and Tissue Research 328 473-486
Baltathakis I, Alcantra O and Boldt DH (2001) Expression of different NF-kB pathway genes in dentritic cells (DCs) or macrophage assessed by gene expression profiling. Journal of Cellular Biochemistry 83 281-290
Baltimore D (1995) Thinking about Howard Temin. Genes & Development 9 1303-1307
Baltimore D and Beg AA (1995) A butterfly flutters by. Nature 373 287-288
Baltz KM, Krusch M, Bringmann A, Bossart P, Mayer F, Kloss M, Baessler T, Kumbier I, Peterfi A, Kupka S, Kroeber S, Menzel D, Radsak MP, Rammensee HG and Salih HR (2007) Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.
FASEB Journal in press
Balu S and Kaiser P (2003) Avian interleukin-12beta (p40): cloning and characterization of the cDNA and gene. Journal of Interferon and Cytokine Research 23 699-707
Balzary RW and Cocks TM (2006) Lipopolysaccharide induces epithelium- and prostaglandin E2-dependent relaxation of mouse isolated trachea through activation of COX-1 and COX-2. Journal of Pharmacology and ExperimentalTherapeutics in press
Bamborough P, Christopher JA, Cutler GJ, Dickson MC, Mellor GW, MOrey JV, Patel CB and Shewchuk LM (2006) Bambou JC, Giraud A, Menard S, Begue B, Rakotobe S, Heyman M, Taddei F, Cerf-Bensussan N and Gaboriau-Routhiau V (2004) In vitro and ex vivo activation of the TLR5 signaling pathway in intestinal epithelial cells by a commensal Escherichia coli strain. Journal of Biological Chemistry 279 42984-42992
Ban HS, Suzuki K, Lim SS, Jung SH, Lee S, Ji J, Lee HS, Lee YS, Shin KH and Ohuchi K (2004) Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2′-hydroxychalcone derivatives in RAW 264.7 cells. Biochemical Pharmacology 67 1549-1557
Ban JO, Hwang IG, Kim TM, Hwang BY, Lee US, Jeong HS, Yoon YW, Kimz DJ and Hong JT (2007) Anti-proliferate and pro-apoptotic effects of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyranone through inactivation of NF-kB in human colon cancer cells. Archives of Pharmacal Research 30 1455-1463
Ban JO, Yuk DY, Woo KS, Kim TM, Lee US, Jeong HS, Kim DJ, Chung YB, Hwang BY, Oh KW and Hong JT (2007) Inhibition of cell growth and induction of apoptosis via inactivation of NF-kB by a sulfurcompound isolated from garlic in human colon cancer cells. Journal of Pharmacological Sciences 104 374-383
Banafsche R, Gunther L, Nefflen JU, Moutsiou S, Knolle PA, Herfarth C and Klar E (2001) NF-kB antisense oligonucleotides reduce leukocyte-endothelial interaction in hepatic ischemia-reperfusion. Transplantation Proceedings 33 3726-3727
Banan A, Farhadi A, Fields JZ, Mutlu E, Zhang L and Keshavarzian A (2003) Evidence that NF-kB activation is critical in oxidant-induced disruption of the microtubule cytoskeleton barrier integrity and that its inactivation is essential in EGF-mediated protection of the monolayers of intestinal epithelia. Journal of Pharmacology and Experimental Therapeutics 306 13-28
Banan A, Fields JZ, Zhang LJ, Shaikh M, Farhadi A and Keshavarzian A (2003) Zeta ({zeta}) Isoform of PKC prevents oxidant-induced NF-kB activation and I-kBa degradation: a fundamental mechanism for EGF protection of the microtubule cytoskeleton and intestinal barrier integrity. Journal of Pharmacology and Experimental Therapeutics 307 53-66
Banan A, Keshavarzian A, Zhang L, Shaikh M, Forsyth CB, Tang Y and Fields JZ (2007) NF-kB activation as a key mechanism in ethanol-induced disruption of the F-actin cytoskeleton and monolayer barrier integrity in intestinal epithelium.Alcohol in press
Banan A, Zhang L, Shaikh M, Fields JZ, Farhadi A and Keshavarzian A (2004) Inhibition of oxidant-induced NF-kB activation I-kBa degradation and instability of F-actin cytoskeletal dynamics barrier function by EGF: key role of PLC-g isoform. Journal of Pharmacology and Experimental Therapeutics 309 356-368
Banan A, Zhang LJ, Farhadi A, Fields JZ, Shaikh M and Keshavarzian A (2004) PKC-{beta}1 isoform activation is required for EGF-induced NF-kB Inactivation and I-kBa stabilization and protection of F-actin assembly and barrier function in enterocyte monolayers. American Journal of Physiology: Cell Physiology 286 C723-C738
Banan A, Zhang L, Shaikh M, Fields JZ, Farhadi A and Keshavarzian A (2004) Novel effect of NF-kB activation –carbonylation and nitration injury to the cytoskeleton and disruption of monolayer barrier in intestinal epithelium. American Journal of Physiology: Cell Physiology 287 C1139-C1151
Banas B, Eberle J, Banas B, Schlondorff D and Luckow B (2001) Modulation of HIV-1 enhancer activity and virus production by cAMP. FEBS Letters 509 207-212
Bancroft CC, Chen Z, Yeh J, Sunwoo JB, Yeh NT, Jackson S, Jackson C and Van Waes C (2002) Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-kappaB and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. International Journal of Cancer 99 538-548
Banda NK, Guthridge C, Sheppard D, Cairns KS, Muggli M, Bech-Otschir D, Dubiel W and Arend WP (2005) Intracellular IL-1 receptor antagonist type 1 inhibits IL-1-induced cytokine production in keratinocytes through binding to the third component of the COP9 signalosome. Journal of Immunology 174 3608-3616
Banday AA, Fazili FR and Lokhandwala MF (2007) Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-kB and protein kinase C. Journal of the American Society ofNephrology in press
Bandino A, Compagnone A, Bravoco V, Cravanzola C, Lomartire A, Rossetto C, Novo E, Cannito S, Valfre di Bonzo L, Zamara E, Autelli R, Parola M and Colmbatto S (2008) beta-Catenin triggers nuclear factor kB-dependent up-regulation of hepatocyte inducible nitric oxide synthase. International Journal of Biochemistry and Cell Biology in press
Bandyophadhaya A, Sarkar M and Chaudhuri K (2007) Human intestinal epithelial cell cytokine mRNA responses mediated by NF-kB are modulated by the motility and adhesion process of Vibrio cholerae. International Journal of Biochemistry & Cell Biology in press
Bandyophadhaya A, Sarkar M and Chaudhuri K (2007) Transcriptional upregulation of inflammatory cytokines in human intestinal epithelial cells following Vibrio cholerae infection. FEBS Journal in press
Bandyopadhyay A, Wang L, Chin SH and Sun LZ (2007) Inhibition of skeletal metastasis by ectopic ERa expression in ERa-negative human breast cancer cell lines. Neoplasia 9 113-118
Bandyopadhyay GK, Yu JG, Ofrecio J and Olefsky JM (2005) Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle. Diabetes 54 2351-2359
Bandyopadhyay S, Starke W, Mieyal J and Gronostajski M (1998) Thioltransferase (glutaredoxin) reactivates the DNA-binding activity of oxidation-inactivated nuclear factor I. Journal of Biological Chemistry 273 392-397
Bandziulis R (1993) Analysis of HIV transcription activation using NF-kB and HeLaScribeTM nuclear extract. Promega Notes 44 44-45
Banerjee A and Gerondakis S (2007) Coordinating TLR-activated signaling pathways in cells of the immune system. Immunology and Cell Biology in press
Banerjee A, Gugasyan R, McMahon M and Gerondakis S (2006) Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells. Proceedings of the National Academy of Sciences USA 103 3274-3279
Banerjee A and Rothman P (1998) IL-7 reconstitutes multiple aspects of v-Abl-mediated signaling. Journal of Immunology 161 4611-4617
Banerjee R, Caruccio L, Zhang YJ, McKercher S and Santella RM (2000) Effects of carcinogen-induced transcription factors on the activation of hepatitis B virus expression in human hepatoblastoma HepG2 cells and its implication on hepatocellular carcinomas. Hepatology 32 367-374
Banerjee S, Bueso-Ramos C and Aggarwal BB (2002) Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kB, cyclooxygenase 2, and matrix metalloprotease 9. Cancer Research 62 4945-4954
Banerjee S, Hussain M, Wang Z, Saliganan A, Che M, Bonfil D, Cher M and Sarkar FH (2007) In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer. Cancer Research67 3818-3826
Banerjee S, Li Y, Wang Z and Sarkar FH (2008) Multi-targeted therapy of cancer by genistein. Cancer Letters in press
Banerjee S, Zhang Y, Ali S, Bhuiyan M, Wang Z, Chiao PJ, Philip PA, Abbruzzese J and Sarkar FH (2005) Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer. Cancer Research 65 9064-9072
Banerjee S, Zhang Y, Wang Z, Che M, Chiao PJ, Abbruzzese J and Sarkar FH (2006) In vitro and in vivo molecular evidence of genistein action in augmenting the efficacy of cisplatin in pancreatic cancer. International Journal of Cancer in press
Banerjee D, Liou H-C and Sen R (2005) c-Rel-dependent priming of naive T cells by inflammatory cytokines. Immunity 23 445-458
Banki Z, Kacani L, Mullauer B, Wilflingseder D, Obermoser G, Niederegger H, Schennach H, Sprinzl GM, Sepp N, Erdei A, Dierich MP and Stoiber H (2003) Cross-linking of CD32 induces maturation of human monocyte-derived dendritic dells via NF-kB signaling pathway. Journal of Immunology 170 3963-3970
Bannerman DD, Eiting KT, Winn RK and Harlan JM (2004) FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kB activation induced by bacterial lipopolysaccharide. American Journal of Pathology 165 1423-1431
Bannerman DD, Tupper JC, Erwert RD, Winn RK and Harlan JM (2002) Divergence of bacterial lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1. Journal of Biological Chemistry 277 8048-8053
Banning A and Brigelius-Floha R (2005) NF-kB, Nrf2, and HO-1 interplay in redox-regulated VCAM-1 expression. Antioxidant and Redox Signaling 7 889-899
Banning A, Schnurr K, Bol GF, Kupper D, Muller-Schmehl K, Viita H, Yla-Herttuala S and Brigelius-Flohe R (2004) Inhibition of basal and interleukin-1-induced vcam-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells. Free Radical Biology and Medicine 36 135-144
Banno T, Gazel A and Blumenberg M (2005) Pathway-specific profiling identifies the NFkB-dependent TNFa-regulated genes in epidermal keratinocytes. Journal of Biological Chemistry 280 18973-18980
Bantel H, Domschke W, Schulze-Osthoff K, Kaskas B and Gregor M (2000) Abnormal activation of transcription factor NF-kB involved in steroid resistance in chronic inflammatory bowel disease. American Journal of Gastroenterology 95 1845-1846
Bantscheff M, Dumpelfeld B and Kuster B (2004) Femtomol sensitivity post-digest 18O labeling for relative quantification of differential protein complex composition. Rapid Communications in Mass Spectrometry 18 869-876
Banzi M, Aguiari G, Trimi V, Mangolini A, Pinton P, Witzgall R, Rizzuto R and Senno LD (2006) Polycystin-1 promotes PKCa-mediated NF-kB activation in kidney cells. Biochemical and Biophysical Research Communications 350 257-262
Bao B, Prasad A, Beck FW and Sarkar F (2007) Zinc up-regulates NF-kB activationvia phosphorylation of IkB in HUT-78 (Th(0)) cells. FEBS Letters in press
Bao B, Prasad AS, Beck FW, Snell D, Suneja A, Sarkar FH, Doshi N, Fitzgerald JT, Swerdlow P (200*) Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients. Translational Research 152 67-80
Bao B, Prasad A, Beck FW, Suneja A and Sarkar F (2006) Toxic effect of zinc on NF-kB, IL-2, IL-2 receptor alpha, and TNF-a in HUT-78 (Th(0)) cells. ToxicologyLetters 166 222-228
Bao BY, Yao J and Lee YF (2006) 1alpha, 25-dihydroxyvitamin D3 suppresses interleukin-8-mediated prostate cancer cell angiogenesis. Carcinogenesis 27 1883-1893
Bao J, Zheng L, Wang Q, Gu CY and Qiu YR and Li J (2006) RelB gene expression in murine bone marrow-derived mature and immature dendritic cells [Article in Chinese]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 22 703-705
Bao J, Zheng L, Zeng FY, Yang HL, Qiu YR, Li J and Wang Q (2007) Relationship between surface molecules and RelB gene expression in DC2.4 cell line [Article in Chinese]. Nan Fang Yi Ke Da Xue Xue Bao 27 56-58
Bao M and Lou Y (2006) Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK. European Journal of Pharmacology 547 22-30
Bao X, Kolli D, Liu T, Shan Y, Garofalo RP and Casola A (2008) Human metapneumovirus small hydrophobic protein inhibits NF-kB transcriptional activity. Journal of Virology in press
Bao X, Liu T, Shan Y, Li K, Garafalo RP and Casola A (2008) Human metapneumovirus glycoprotein G inhibits innate immune responses. PLoS Pathogenesis 4 e1000077
Bao X, Liu T, Spetch L, Kolli D, Garofalo RP and Casola A (2007) Airway epithelial cell response to human metapneumovirus infection. Virology in press
Bao X, Lu C and Frangos JA (1999) Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: role of NO, NFkB, and egr-1. Arteriosclerosis, Thrombosis and Vascular Biology 19 996-1003
Bao Y, Jia RH, Yuan J and Li J (2007) Rosiglitazone ameliorates diabetic nephropathy by inhibiting reactive oxygen species and its downstream-signaling pathways. Pharmacology 80 57-64
Bao Z, Lim S, Liao W, Lin Y, Thiemermann C, Leung BP and WOng WS (2007) Glycogen synthase kinase-3b inhibition attenuates asthma in mice. American Journal ofRespiratory Critical Care Medicine in press
Baouz S, Giron-Michel J, Azzarone B, Giuliani M, Cagnoni G, Olsson S, Testi T, Gabbiani G and Canonica GW (2005) Lung myofibroblasts as targets of salmeterol and fluticasone propionate: inhibition of alpha-SMA and NF-kB. International Immunology 17 1473-1481
Bar-Shai M, Carmeli E, Coleman R, Rozen N, Perek S, Fuchs D and Reznick AZ (2005) The effect of hindlimb immobilization on acid phosphatase, metalloproteinases and nuclear factor-kB in muscles of young and old rats. Mechanisms of Ageing and Development 126 289-297
Bar-Shai M, Carmeli E, Ljubuncic P and Reznick AZ (2008) Exercise and immobilization in aging animals: The involvement of oxidative stress and NF-kB activation. Free Radical Biology and Medicine 44 202-214
Bar-Shai M, Carmeli E and Reznick AZ (2005) The role of NF-kB in protein breakdown in immobilization, aging, and exercise: from basic processes to promotion of health. Annals of the New York Academy of Sciences 1057 431-447
Bar-Shai M, Hasnis E, Wiener-Megnazi Z and Reznick AZ (2006) The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-kB and implication to inflammatory processes. Journal of Physiology and Pharmacology 57 S39-S44
Bar-Shai M and Reznick AZ (2006) Peroxynitrite induces an alternative NF-kB activation pathway in l8 rat myoblasts.
Antioxidant and Redox Signaling 8 639-652
Bar-Shai M and Reznick AZ (2006) Reactive nitrogen species induce nuclear factor-kB-mediated protein degradation in skeletal muscle cells. Free RadicalBiology and Medicine 40 2112-2125
Bar-Yehuda S, Silverman MH, Kerns WD, Ochaion A, Cohen S and Fishman P (2007) The anti-inflammatory effect of A(3) adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis. Expert Opinion on Investigational Drugs 16 1601-1613
Bar-Yehuda S, Stemmer SM, Madi L, Castel D, Ochaion A, COhen S, Barer F, Zabutti A, Perez-Liz G Del Valle L and Fishman P (2008) The A3 adenosine receptor agonist CF102 induces apoptosis of hepatocellular carcinoma via de-regulation of the Wnt and NF-kB signal transduction pathways. International Journal of Oncology 33 287-295
Baral C, Chancellor K, Tran N, Tran NL, Joy A, Berens M (2004) A knowledge based approach for representing and reasoning about signaling networks. Bioinformatics 20 Suppl 1 I15-I22
Baran CP, Tridandapani S, Helgason CD, Humphries RK, Krystal G and Marsh CB (2003) The inositol 5′-phosphatase SHIP-1 and the Src-kinase Lyn negatively regulate M-CSF-induced Akt activity. Journal of Biological Chemistry 278 38628-38636
Baran-Marszak F, Fagard R, Girard B, Camilleri-Broet S, Zeng F, Lenoir GM, Raphael M and Feuillard J (2002) Gene array identification of Epstein Barr virus-regulated cellular genes in EBV-converted Burkitt lymphoma cell lines. Laboratory Investigation 82 1463-1479
Baran-Marszak F, Laguillier C, Youlyouz I, Feuillard J, Mariette X, Fagard R and Raphael M (2006) Effect of tumor necrosis factor alpha and infliximab on apoptosis of B lymphocytes infected or not with Epstein-Barr virus. Cytokine 33 337-345
Baranek T, Debret R, Antonicelli F, Lamkhioued B, Belaaouaj A, Hornebeck W, Bernard P, Guenounou M and Le Naour R (2007) Elastin receptor (spliced galactosidase) occupancy by elastin peptides counteracts proinflammatory cytokine expression in lipopolysaccharide-stimulated human monocytes through NF-kB down-regulation. Journal of Immunology 179 6184-6192
Baranova I, Vishnyakova T, Bocharov A, Chen Z, Remaley AT, Stonik J, Eggerman TL and Patterson AP (2002) Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells. Infection and Immunity 70 2995-3003
Barat C and Tremblay MJ (2002) Engagement of CD43 enhances human immunodeficiency virus type 1 transcriptional activity and virus production that is induced upon TCR/CD3 stimulation. Journal of Biological Chemistry 277 28714-28724
Barbacid M, Hunter E and Aaronson SA (1979) Avian reticuloendotheliosis viruses: evolutionary linkage with mammalian type C retroviruses. Journal of Virology 30 508-514
Barbakadze T, Zhuravliova E, Sepashvili M, Zaalishvili E, Ramsden JJ, Bator J, Szeberenyi J and Mikeladze D (2005) Production of homocysteine in serum-starved apoptotic PC12 cells depends on the activation and modification of Ras. Neuroscience Letters 39 56-61
Barbaroux JB, Beleut M, Brisken C, Mueller CG and Groves RW (2008) Epidermal receptor activator of NF-kB ligand controls langerhans cells numbers and proliferation. Journal of Immunology 181 1103-1108
Barbe-Tuana FM, Klein D, Ichii H, Berman DM, Coffey L, Kenyon NS, Ricordi C and Pastori RL (2006) CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets. Diabetes 55 2437-2445
Barbera MJ, Puig I, Dominguez D, Julien-Grille S, Guaita-Esteruelas S, Peiro S, Baulida J, Franci C, Dedhar S, Larue L and Garcia De Herreros A (2004) Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells. Oncogene 23 7345-7354
Barbieri SS, Cavalca V, Eligini S, Brambilla M, Caiani A, Tremoli E and Colli S (2004) Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. Free Radical Biology and Medicine 37 156-165
Barboric M, Nissen RM, Kanazawa S, Jabrane-Ferrat N and Peterlin BM (2001) NF-kB binds P-TEFb to stimulate transcriptional elongation by RNA polymerase II. Molecular Cell 8 327-337
Barcellini W, Zaninoni A, Imperiali FG, Boschetti C, Colombi M, Iurlo A and Zanella A (2007) Anti-erythroblast autoimmunity in early myelodysplastic syndromes. Haematologica 92 19-26
Barchowsky A, Roussel RR, Krieser RJ, Mossman BT and Treadwell MD (1998) Expression and activity of urokinase and its receptor in endothelial and pulmonary endothelial cells exposed to asbestos. Toxicology and Applied Pharmacology 152 388-396
Barchowsky A, Soucy NV, O’Hara KA, Hwa J, Noreault TL and Andrew AS (2002) Novel pathway for nickel-induced interleukin-8 expression. Journal of Biological Chemistry 277 24225-24231
Barcova M, Speth C, Kacani L, Uberall F, Stoiber H and Dierich MP (1999) Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1. Pflugers Arch 437 538-546
Bardag-Gorce F, French BA, Joyce M, Baires M, Montgomery RO, Li J and French S (2007) Histone acetyltransferase p300 modulates gene expression in an epigenetic manner at high blood alcohol levels. Experimental and Molecular Pathology in press
Bardaro T, Falco G, Sparago A, Mercadante V, Gean Molins E, Tarantino E, Ursini MV and D’Urso M (2003) Two cases of misinterpretation of molecular results in incontinentia pigmenti, and a PCR-based method to discriminate NEMO/IKKg gene deletion. Human Mutation 21 8-11
Bardelli C, Gunella G, Varsaldi F, Balbo P, Del Boca E, Bernardone IS, Amoruso A and Brunelleschi S (2005) Expression of functional NK(1) receptors in human alveolar macrophages: superoxide anion production, cytokine release and involvement of NF-kB pathway. British Journal of Pharmacology 145 385-396
Barbagna-Mohan P, Ravindranath PP and Mohan R (2006) Small molecule anti-angiogenic probes of the ubiquitin proteasome pathway: potential application to choroidal neovascularization. Investigative Ophthalmology & Visual Science 47 4138-4145
Barger SW, Moerman AM and Mao X (2005) Molecular mechanisms of cytokine-induced neuroprotection: NFkB and neuroplasticity. Current Pharmaceutical Design 11 985-998
Bargou RC, Emmerich F, Krappmann D, Bommert K, Mapara MY, Arnold W, Royer HD, Grinstein E, Greiner A, Scheidereit C and Dörkin B (1997) Constitutive NF-kB-RelA activation is required for proliferation and survival of Hodgkin’s disease tumor cells. Journal of Clinical Investigation 100 2961-2969
Bargou RC, Leng C, Krappmann D, Emmerich F, Mapara MY, Bommert K, Royer H-D, Scheidereit C and Dörken B (1996) High-level nuclear NF-kB and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells. Blood 87 4340-4347
Barhoumi R, Faske J, Liu X and Tjalkens RB (2004) Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kB. Brain Research Molecular Brain Research 122 167-179
Barillas-Mury C, Charlesworth A, Gross I, Richman A, Hoffmann JA and Kafatos FC (1996) Immune factor Gambif1, a new rel family member from the human malaria vector, Anopheles gambiae. EMBO Journal 15 4691-4701
Barinaga M (1996) Apoptosis: a life-death balance within the cell. Science 274 724
Barish GD and Evans RM (2004) A nuclear strike against Listeria- the evolving life of LXR. Cell 119 149-151
Barisic S, Strozyk E, Peters N, Walczak H and Kulms D (2008) Identification of PP2A as a crucial regulator of the NF-kB feedback loop: its inhibition by UVB turns NF-kB into a pro-apoptotic factor. Cell Death and Differentiation in press
Baritaki S, Katsman A, Chatterjee D, Yeung KC, Spandidos DA and Bonavida B (2007) Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation. Journal of Immunology 179 5441-5453
Baritaki S, Suzuki E, Umezawa K, Spandidos DA, Berenson J, Daniles TR, Penichert ML, Jazireli AR, Palladino M and Bonavida B (2008) Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells. Journal of Immunology 180 6199-6210
Barlic J, Zhang Y and Murphy PM (2007) Atherogenic lipids induce adhesion of human coronary artery smooth muscle cells to macrophages by upregulating chemokine CX3CL1 on smooth muscle cells in a TNFa-NFkB-dependent manner. Journal of Biological Chemistry in press
Bartitaki S, Huerta-Yepez S, Sakai T, Spandidos DA and Bonavida B (2007) Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1. Mol Cancer Therapy 6 1387-1399
Barken D, Wang CJ, Kearns J, Cheong R, Hoffmann A and Levchenko A (2005) Comment on “Oscillations in NF-kB signaling control the dynamics of gene expression”. Science 308 52
Barker M, Clackers M Copley R, Demaine DA, Humphreys D, Inglis GG, Johnston MJ, Jones HT, Haase MV, House D, Loiseau R, Nisbet L, Pacquet F, Skone PA, Shanahan SE, Tape D, Vinader VM, Washington M, Uings I Upton R, McLay IM and Nacdonald SJ (2006) Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series. Journal ofMedicinal Chemistry 49 4216-4231
Barkett M and Gilmore TD (1999) Control of apoptosis by Rel/NF-kB transcription factors. Oncogene 18 6910-6924
Barkett M, Dooher JE, Lemonnier L, Simmons L, Scarpat JN, Wang J and Gilmore TD (2001) Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3. Biochemica et Biophysica Acta 1526 25-36
Barkett M, Xue D, Horvitz HR & Gilmore TD (1997) Phosphorylation of IkB-a inhibits its cleavage by caspase CPP32 in vitro. Journal of Biological Chemistry 272 29419-29422
Barlic J, McDermott DH, Merrell MN, Gonzales J, Via LE and Murphy PM (2004) IL-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms. Journal of Biological Chemistry 279 48520-48534
Barnes PJ (1998) Anti-inflammatory actions of glucocorticoids: molecular mechanisms. Clincial Science 94 557-562
Barnes PJ (2003) New treatments for chronic obstructive pulmonary disease. Ann Ist Super Sanita 39 573-582
Barnes PJ (2004) COPD: is there light at the end of the tunnel? Current Opinion in Pharmacology 4 263-272
Barnes PJ (2004) New drugs for asthma. Nature Review Drug Discovery 3 831-444
Barnes PJ (2005) Targeting histone deacetylase 2 in chronic obstructive pulmonary disease treatment. Expert Opinion on Therapeutic Targets 9 1111-1121
Barnes PJ (2006) Corticosteroids: the drugs to beat. European Journal of Pharmacology 27 413-426
Barnes PJ (2006) Transcription factors in airway diseases.
Laboratory Investigation 86 867-872
Barnes PJ (2007) New molecular targets for the treatment of neutrophilic diseases. Journal of Allergy and Clinical Immunology in press
Branes PJ (2008) Frontrunners in novel pharmacotherapy of COPD. Current Opinions in Pharmacology in press
Barnes PJ, Adcock IM and Ito K (2005) Histone acetylation and deacetylation: importance in inflammatory lung diseases. European Respiration Journal 25 552-563
Barnes PJ and Hansel TT (2004) Prospects for new drugs for chronic obstructive pulmonary disease. Lancet 364 985-996
Barnes PJ and Karin M (1997) Nuclear factor-kB: a pivotal transcription factor in chronic inflammatory diseases. New England Journal of Medicine 336 1066-1071
Barnhart BC and Peter ME (2003) The TNF receptor 1: a split personality complex. Cell 114 147-149
Barnhart BC, Legembre P, Pietras E, Bubici C, Franzoso G and Peter ME (2004) CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells. EMBO Journal 23 3175-3185
Barnich N, Aguirre JE, Reinecker HC, Xavier R and Podlosky DK (2005) Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-kB activation in muramyl dipeptide recognition. Journal of Cell Biology 170 21-26
Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC and Podolsky DK (2005) GRIM-19 interacts with NOD2 and serves as down-stream effector of anti-bacterial function in intestinal epithelial cells. Journal of Biological Chemistry 280 19021-19026
Barone M, Spano D, D’Apolito M, Centra M, Lasalandra C, Capasso M, Di Leo A, Volinia S, Arcelli D, Rosso N, Francavilla A, Tiribelli C and Iolascon A (2006) Gene expression analysis in HBV transgenic mouse liver: a model to study early events related to hepatocarcinogenesis. Molecular Medicine 12 115-123
Barquero AA, Michelini FM and Alche LE (2006) 1-Cinnamoyl-3,11-dihydroxymeliacarpin is a natural bioactive compound with antiviral and nuclear factor-kB modulating properties. Biochemical and Biophysical Research Communication 344 955-962
Barr J, Sharma CS, Sarkar S, Wise K, Dong L, Periyakaruppan A and Ramesh GT (2006) Nicotine induces oxidative stress and activates nuclear transcription factor kappa B in rat mesencephalic cells. Molecular and Cellular Biochemistry in press
Barragan M, Campas C, Bellosillo B and Gil J (2003) Protein kinases in the regulation of apoptosis in B-cell chronic lymphocytic leukemia. Leukemia and Lymphoma 44 1865-1870
Barre B and Perkins ND (2007) A cell cycle regulatory network controlling NF-kB subunit activity and function. EMBO Journal in press
Barrett KE (2005) A new twist on trefoils. Focus on “TFF3 modulates NF-kB and a novel regulatory molecule of NF-kB in intestinal epithelial cells via a mechanism distinct from TNF-alpha. American Journal of Physiology: Cellular Physiology 289 C1069-C1071
Barrett TQ, Kristiansen LH and Ovesen T (2003) NF-kB in cultivated middle ear epithelium. International Journal of Pediatric Otorhinolaryngology 67 895-903
Barroga CF, Stevenson JK, Schwarz EM and Verma IM (1995) Constitutive phosphorylation of IkBa by casein kinase II. Proceedings of the National Academy of Sciences USA 92 7637-7641
Barrow RE and Dasu MR (2005) Oxidative and heat stress gene changes in hypertrophic scar fibroblasts stimulated with interleukin-1beta. Journal of Surgical Research 126 59-65
Barsness KA, Arcaroli J, Harken AH, Abraham E, Banerjee A, Reznikov L and McIntyre Jr RC (2004) Hemorrhage-induced acute lung injury is TLR-4 dependent. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 287 R592-R599
Bartels M, Schweda AT, Dreikhausen U, Frank R, Resch K, Beil W and Nourbakhsh M (2007) Peptide-mediated disruption of NFkB/NRF interaction inhibits IL-8 gene activation by IL-1 or Helicobacter pylori. Journal of Immunology 179 7605-7613
Bartfai T, Behrens MM, Gaidarova S, Pemberton J, Shivanyuk A and Rebek J Jr (2003) A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses. Proceedings of the National Academy of Sciences USA 100 7971-7976
Barth CF and Humphries EH (1988) A non-immunosuppressive helper virus allows high efficiency induction of B-cell lymphomas by reticuloendotheliosis virus strain T. Journal of Experimental Medicine 167 89-108
Barth CF and Humphries EH (1988) Expression of v-rel induces mature B-cell lines that reflect the diversity of avian immunoglobulin heavy- and light-chain rearrangements. Molecular and Cellular Biology 8 5358-5368
Barth CF, Ewert DL, Olson WC and Humphries EH (1990) Reticuloendotheliosis virus REV-T(REV-A)-induced neoplasia: development of tumors within the T-lymphoid and myeloid lineages. Journal of Virology 64 6054-6062
Barth TF, Martin-Subero JI, Joos S, Menz CK, Hasel C, Mechtersheimer G, Parwaresch RM, Lichter P, Siebert R and Moeller P (2003) Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin’s lymphoma. Blood 101 3681-3686
Barth TFE, Dohner H, Werner CA, Stilgenbauer S, Schlotter M, Pawlita M, Lichter P, Moller P, Bentz M (1998) Characteristic pattern of chromosomal gains and losses in primary large B-cell lymphomas of the gastrointestinal tract. Blood 91 4321-4330
Bartholin L, Guindon S, Martel S, Corbo L and Rimokh R (2007) Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter. Genein press
Bartholoma P, Erlandsson N, Kaufmann K, Rossler OG, Baumann B, Wirth T, Giehl KM and Thiel G (2002) Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kB and extracellular signal-regulated protein kinase activation. Biochemical Pharmacology 63 1507-1516
Bartholomeu DC, Ropert C, Melo MB, Parroche P, Junqueira CF, Teixeira SM, Sirois C, Kasperkovitz P, Knetter CF,Lien E, Latz E, Goelnbock DT and Gazzinelli RT (2008) Recruitment and endo-lysosomal activation of TLR9 in dendritic cells infected with Trypanosoma cruzi. Journal of Immunology 181 1333-1344
Bartke T, Siegmund D, Peters N, Reichwein M, Henkler F, Scheurich P and Wajant H (2001) p53 upregulates cFLIP, inhibits transcription of NF-kB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells. Oncogene 20 571-580
Barton ES, Forrest JC, Connolly JL, Chappell JD, Liu Y, Schnell FJ, Nusrat A, Parkos CA and Dermody TS (2001) Junction adhesion molecule is a receptor for reovirus. Cell 104 441-451
Barton GM and Medzhitov R (2004) Toll signaling: RIPping off the TNF pathway. Nature Immunology 5 472-474
Barton JL, Berg T, Didon L and Nord M (2007) The pattern recognition receptor Nod1 activates CCAAT/enhancer binding protein {beta} signalling in lung epithelial cells.
European Respiratory Journal 30 214-222
Barve V, Ahmed F, Adsule S, Banerjee S, Kulkarni S, Katiyar P, Anson CE, Powell AK, Padhye S and Sarkar FH (2006) Synthesis, molecular characterization, and biological activity of novel synthetic derivatives of chromen-4-one in human cancer cells.
Journal of Medicinal Chemistry 49 3800-3808
Bar-Yehuda S, Madi L, Silberman D, Gery S, Shkapenuk M and Fishman P (2005) CF101, an agonist to the A(3) adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model. Neoplasia 7 85-90
Basak C, Pathak SK, Bhattacharyya A, Mandal D, Pathak S and Kundu M (2005) NF-kB-and C/EBP beta-driven interleukin-1beta gene expression and PAK1-mediated caspase 1 activation play essential roles in interleukin-1beta release from Helicobacter pylori lipopolysaccharide (LPS)-stimulated macrophages. Journal of Biological Chemistry 280 4279-4288
Basak S and Hoffmann A (2008) Crosstalk via the NF-kB signaling system. Cytokine and Growth Factor Reviews in press
Basak S, Kim H, Kearns JD, Tergaonkar V, O’Dea E, Werner SL, Benedict CA, Ware CF, Ghosh G, Verma IM and Hoffmann A (2007) A fourth IkB protein within the NF-kB signaling module. Cell 128 369-381
Basak S, Shih VF and Hoffmann A (2008) Generation and activation of multiple dimeric transcription factors within the NF-kB signaling system. Molecular and Cellular Biology in press
Basel-Vanagaite L, Attia R, Yahav M, Ferland RJ, Anteki L, Walsh CA, Olender T, Straussberg T, Magal N, Taub E, Drasinover V, Alkelai A, Bercovich D, Rechavi G, Simon AJ and Shohat M (2006) The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive nonsyndromic mental retardation. Journal of Medical Genetics 43 203-210
Bash J, Zong W-X and Gélinas C (1997) c-Rel arrests the proliferation of HeLa cells and affects critical regulators of the G1/S-phase transition. Molecular and Cellular Biology 17 6526-6536
Bash J, Zong W-X, Banga S, Rivera A, Ballard DW, Ron Y and Gelinas C (1999) Rel/NF-kB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors. EMBO Journal 18 2803-2811
Basha MR, Braddy NS, Zawia NH and Kodavanti PR (2005) Ontogenetic alterations in prototypical transcription factors in the rat cerebellum and hippocampus following perinatal exposure to a commercial PCB mixture. Neurotoxicology 27 118-124
Basheer R, Bauer A, Elmenhorst D, Ramesh V and McCarley RW (2007) Sleep deprivation upregulates A1 adenosine receptors in the rat basal forebrain. Neuroreport 18 1895-1899
Basheer R, Rainnie DG, Porkka-Heiskanen T, Ramesh V and McCarley RW (2001) Adenosine, prolonged wakefulness, and A1-activated NF-kappaB DNA binding in the basal forebrain of the rat. Neuroscience 104 731-739
Basile JR, Eichten A, Zacny V and Munger K (2003) NF-kB-mediated induction of p21(Cip1/Waf1) by tumor necrosis factor alpha induces growth arrest and cytoprotection in normal human keratinocytes. Molecular Cancer Research 1 262-270
Bassaganya-Riera J, Reynolds K, Martino-Catt S, Cui Y, Hennighausen L, Gonzalez F, Rohrer J, Benninghoff AU and Hontecillas R (2004) Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroenterology 127 777-791
Basseres DS and Baldwin AS (2006) Nuclear factor-kB and inhibitor of kB kinase pathways in oncogenic initiation and progress. Oncogene 25 6817-6830
Bassett SE, Fennewald SM, King DJ, Li X, Herzog NK, Shope R, Aronson JF, Luxon BA and Gorenstein DG (2004) Combinatorial selection and edited combinatorial selection of phosphorothioate aptamers targeting human nuclear factor-kB RelA/p50 and RelA/RelA. Biochemistry 43 9105-9115
Basso K, Klein U, Niu H, Stolovitzky GA, Tu Y, Califano A, Cattoretti G and Dalla-Favera R (2004) Tracking CD40 signaling during germinal center development. Blood 104 4088-4096
Bastard JP,Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J and Feve B (2006) Recent advances in the relationship between obesity, inflammation, and insulin resistance. European Cytokine Network 17 4-12
Basu A, Mohanty S and Sun B (2001) Differential sensitivity of breast cancer cells to tumor necrosis factor-alpha: involvement of protein kinase C. Biochemical and Biophysical Research Communications 280 883-891
Basu S and Matsutake T (2004) Heat shock protein-antigen presenting cell interactions. Methods 32 38-41
Basu S, Pathak S, Pathak SK, Bhattacharyya A, Banerjee A, Kundu M and Basu J (2007) Mycobacterium avium-induced matrix metalloproteinase-9 expression occurs in a cyclooxygenase-2-dependent manner and involves phosphorylation- and acetylation-dependent chromatin modification. Cellular Microbiology in press
Bates DL, Barthel KK, Wu Y, Kalhor R, Stroud JC, Giffin MJ and Chen L (2008) Crystal structure of NFAT bound to the HIV-1 LTR randem kB enhancer element. Structure 16 684-694
Bates GJ, Nicol SM, Wilson BJ, Jacobs AM, Bourdon JC, Wardrop J, Gregory DJ, Lane DP, Perkins ND and Fuller-Pace FV (2005) The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor. EMBO Journal 24 543-553
Bates PW and Miyamoto S (2004) Expanded nuclear roles for IkBs. Sci STKE 254 pe48
Bates RC, DeLeo MJ 3rd and Mercurio AM (2004) The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis. Experimental Cell Research 299 315-324
Batkai S, Rajesh M, Mukhopadhyay P, Hasko G, Liaudet L, Cravatt BF, Csiszar A, Ungvari ZI and Pacher P (2007) Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression and apoptosis in mice lacking fatty acid amide hydrolase. American Journal of Physiology: Heart andCirculatory Physiology in press
Batmunkh C, Krajewski J, Jelkmann W and Hellwig-Burgel T (2006) Erythropoietin production: Molecular mechanisms of the antagonistic actions of cyclic adenosine monophosphate and interleukin-1. FEBS Letters 580 3153-3160
Batra RK, Guttridge DC, Brenner DA, Dubinett SM, Baldwin AS and Boucher RC (1999) IkBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death. American Journal of Respiratory Cell and Molecular Biology 21 238-245
Batra RK, Lin Y, Sharma S, Dohadwala M, Luo J, Pold M and Dubinett SM (2003) Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an IkB kinase-dependent mechanism. Cancer Research 63 642-646
Battaglino R, Fu J, Spate U, Ersoy U, Joe M, Sedaghat L and Stashenko P (2004) Serotonin regulates osteoclast differentiation through its transporter. Journal of Bone and Mineral Research 19 1420-1431
Battaglino R, Kim D, Fu J, Vaage B, Fu XY and Stashenko P (2002) c-myc is required for osteoclast differentiation. Journal of Bone and Mineral Research 17 763-773
Bataller R, Paik YH, Lindquist JN, Lemasters JJ and Brenner DA (2004) Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology 126 529-540
Batkai S, Rajesh M, Mukhopadhyay P, Hasko G, Liaudet L, Cravatt BF, Csiszar A, Ungvari ZI and Pacher P (2007) Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression and apoptosis in mice lacking fatty acid amide hydrolase. American Journal of Physiology: Heart andCirculatory Physiology in press
Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L and Bosco MC (2007) Hypoxia transcriptionally induces macrophage-inflammatory protein-3{alpha}/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kB. Journal of Leukocyte Biology inpress
Battle J, Ha T, Li C, Della Beffa V, Rice P, Kalbfleisch J, Browder W and Williams D (1998) Ligand bindng ot the (1->3)-b-D-glucan receptor stimulates NFkB activation, but not apoptosis in U937 cells. Biochemical and Biophysical Research Communications 249 499-504
Battle TE and Frank DA (2002) The role of STATs in apoptosis. Current Molecular Medicine 2 381-392
Batuman V (2007) Proximal tubular injury in myeloma. Contributions in Nephrology153 87-104
Bauch A and Superti-Furga G (2006) Charting protein complexes, signaling pathways, and networks in the immune system. Immunological Reviews 210 187-207
Baud V and Karin M (2001) Signal transduction by tumor necrosis factor and its relatives. Trends in Cell Biology 11 372-377
Baud V, Liu -G-Z, Bennett B, Suzuki N, Xia Y and Karin M (1999) Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes & Development 13 1297-1308
Baud’huin M, Duplomb L, Ruiz Velasco C, Fortun Y, Heymann D and Padrines M (2007) Key roles of the OPG-RANK-RANKL system in bone oncology. Expert Reviews of Anticancer Therapy 7 221-232
Bauer A, Villunger A, Labi V, Fischer SF, Strasser A, Wagner H, Schmid RM and Hacker G (2006) The NF-kB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells. Proceedings of the National Academy ofSciences USA 103 10979-10984
Bauer B, Krumbock N, Fresser F, Hochholdinger F, Spitaler M, Simm A, Uberall F, Schraven B and Baier G (2001) Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kB transactivation cascade in Jurkat T cells. Journal of Biological Chemistry 276 31627-31634
Bauer CM, Cewitte-Orr SJ, Hornby KR, Zavitz CC, Lichty BD, Stampfli MR nad Mossman KL (2008) Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells. Journal of Interferon and Cytokine Research 28 167-179
Bauer JA, Lupica JA, Schmidt H, Morrison BH, Haney RM, Masci RK, Lee RM, Didonato JA and Lindner DJ (2007) Nitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signaling. PLoS ONE 2 e1313
Bauge C, Attia J, Leclercq S, Pujol JP, Galera P and Boumediene K (2007)Interleukin-1beta up-regulation of Smad7 via NF-kB activation in human chondrocytes. Arthritis and Rheumatism 58 221-226
Bauge C, Legendre F, Leclercq S, Elissalde JM, Pujol JP, Galera P and Boumediene K (2007) Interleukin-1beta impairment of transforming growth factor beta1 signaling by down-regulation of transforming growth factor beta receptor type II and up-regulation of Smad7 in human articular chondrocytes.
Arthritis and Rheumatism 56 3020-3032
Baulig A, Garlatti M, Bonvallot V, Marchand A, Barouki R, Marano F and Baeza-Squiban A (2003) Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 285 L671-L679
Baum L and Ng A (2004) Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer’s disease animal models. Journal of Alzheimers’ Disease 6 367-377
Baumann B, Bohnenstengel F, Siegmund D, Wajant H, Weber C, Herr I, Debatin KM, Proksch P and Wirth T (2002) Rocaglamide derivatives are potent inhibitors of NF-kB activation in T-cells. Journal of Biological Chemistry 277 44791-44800
Baumann B, Seufert J, Jakob F, Noth U, Rolf O, Eulert J and Rader CP (2005) Activation of NF-kB signalling and TNFalpha-expression in THP-1 macrophages by TiAlV- and polyethylene-wear particles. Journal of Orthopedic Research 23 1241-1248
Baumann B, Wagner M, Aleksic T, von Wichert G, Weber CK, Adler G and Wirth T (2007) Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo. Journal of Clinical Investigation in press
Baumann B, Weber CK, Troppmair J, Whiteside S, Israel A, Rapp UR and Wirth T (2000) Raf induces NF-kB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation. Proceedings of the National Academy of Sciences USA 97 4615-4620
Baumgarten G, Knuefermann P, Nozaki N, Sivasubramanian N, Mann DL and Vallejo JG (2001) In vivo expression of proinflammatory mediators in the adult heart after endotoxin administration: the role of toll-like receptor-4. Journal of Infectious Diseases 183 1617-1624
Baumgarten G, Knuefermann P, Wrigge H, Putensen C, Stapel H, Fink K, Meyer R, Hoeft A and Grohe (2006) Role of Toll-like receptor 4 for the pathogenesis of acute lung injury in Gram-negative sepsis. European Journal of Anaesthesiology 23 1041-1048
Baumgartner B, Weber M, Quirling M, Fischer C, Page S, Adam M, Von Schilling C, Waterhouse C, Schmid C, Neumeier D and Brand K (2002) Increased IkB kinase activity is associated with activated NF-kB in acute myeloid blasts. Leukemia 16 2062-2071
Baumstark-Khan C, Hellweg CE, Arenz A and Meier MM (2005) Cellular monitoring of the nuclear factor kappaB pathway for assessment of space environmental radiation. Radiation Research 164 527-530
Baus-Loncar M, Al-Azzeh ED, Romanska H, Lalani el-N, Stamp GW, Blin N and Kayademir T (2004) Transcriptional control of TFF3 (intestinal trefoil factor) via promoter binding sites for the nuclear factor kB and C/EBPbeta. Peptides 25 849-854
Baust H, Schoke A, Brey A, Gern U, Los M, Schmid RM, Rottinger EM and Seufferlein T (2003) Evidence for radiosensitizing by gliotoxin in HL-60 cells: implications for a role of NF-kB independent mechanisms. Oncogene 22 8786-8796
Bava SV, Puliappadamba VT, Deepti A, Nair A, Karunagaran D and Anto RJ (2004) Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kB and the serine/threonine kinase Akt and is independent of tubulin polymerization. Journal of Biological Chemistry 280 6301-6308
Bavendiek U, Libby P, Kilbride M, Reynolds R, Mackman N and Schonbeck U (2002) Induction of tissue factor expression in human endothelial cells via CD40 ligand is mediated by AP-1, NF-kB, and Egr-1. Journal of Biological Chemistry 277 25032-25039
Bayon Y, Alonso A and Sanchez Crespo M (1999) 4-trifluoromethyl derivatives of salicylate, triflusal and its main metabolite 2-hydroxy-4-trifluoromethylbenzoic acid, are potent inhibitors of nuclear factor kB activation. British Journal of Pharmacology 126 1359-1366
Baxa DM and Yoshimura FK (2003) Genistein reduces NF-kB in T lymphoma cells via a caspase-mediated cleavage of IkBa. Biochemical Pharmacology 66 1009-1018
Baxendale AJ, Dawson CW, Stewart SE, Mudaliar V, Reynolds G, Gordon J, Murray PG, Young LS and Eliopoulos AG (2005) Constitutive activation of the CD40 pathway promotes cell transformation and neoplastic growth. Oncogene 24 7913-7923
Baxter A, Brough S, Cooper A, Floettmann E, Foster S, Harding C, Kettle J, McInally T, Martin C, Mobbs M, Needham M, Newham P, Paine S, St-Gallay S, Salter S, Unitt J and Xue Y (2004) Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors. Bioorganic Medicinal Chemistry Letters 14 2817-2822
Baxter FO, Came PJ, Abell K, Kedjouar B, Huth M, Rajewsky K, Pasparakis M and Watson CJ (2006) IKKbeta/2 induces TWEAK and apoptosis in mammary epithelial cells. Development 133 3485-3494
Baxter FO, Neoh K, and Tevendale MC (2007) The beginning of the end: death signaling in early involution. Journal of Mammary Gland Biology and Neoplasia in press
Bayat H, Xu S, Pimentel D, Cohen RA and Jiang B (2007) Activation of thromboxane receptor upregulates interleukin (IL)-1b induced VCAM-1 expression through JNK signaling. Arterioslerosis, Thrombosis, and Vascular Biology in press
Bayon Y, Alonso A, Hernandez M, Nieto ML and Sanchez Crespo M (1998) Mechanisms of cell signaling in immune-mediated inflammation. Cytokines, Cellular & Molecular Therapy 4 275-286
Bayon Y, Ortiz MA, Lopez-Hernandez FJ, Gao F, Karin M, Pfahl M and Piedrafita FJ (2003) Inhibition of IkB Kinase by a new class of retinoid-related anticancer agents that induce apoptosis. Molecular and Cellular Biology 23 1061-1074
Bayram H, Ito K, Issa R, Ito M, Sukkar M and Chung KF (2006) NF-kB-dependent regulation of the timing of activation-induced cell death of T lymphocytes.Journal of Immunology 176 2183-2189
Bea F, Kreuzer J, Preusch M, Schaab S, Isermann B, Rosenfeld ME, Katus H and Blessing E (2006) Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology in press
Bea S, Colomo L, Lopez-Guillermo A, Salaverria I, Puig X, Pinyol M, Rives S, Montserrat E and Campo E (2004) Clinicopathologic significance and prognostic value of chromosomal imbalances in diffuse large B-cell lymphomas. Journal of Clinical Oncology 22 3498-3506
- Bea S, Zettl A, Wright G, Salaverria I, Jehn P, Moreno V, Burek C, Ott G, Puig X, Yang L, Lopez-Guillermo A, Chan WC, Weisenburger DD, Armitage JO, Gascoyne RD, Connors JM, Grogan TM, Braziel R, Fisher RI, Smeland EB, Kvaloy S, Delabie J, Simon R, Wilson WH, Jaffe ES, Montserrat E, Muller-Hermelink H-K, Staudt LM, Campo E & Rosenwald A (2005) Diffuse large B-cell lymphoma subgroups have distinct genetic profiles that influence tumor biology and improve gene expression-based survival prediction. Blood 106 3183-3190
Beak SM, Lee YS and Kim JA (2004) NADPH oxidase and cyclooxygenase mediate the ultraviolet B-induced generation of reactive oxygen species and activation of nuclear factor-kappaB in HaCaT human keratinocytes. Biochimie 86 425-429
Beaulieu F, Ouellet C, Ruediger EH, Belema M, Qiu Y, Yang X, Banville J, Burke JR, Gregor KR, Macmaster JF, Martel A, McIntyre KW, Pattoli MA, Zusi FC and Vyas D (2006) Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors. Bioorganic & Medicinal Chemistry Letters in press
Bearer EL (1994) Distribution of Xrel in the early Xenopus embryo: a cytoplasmic and nuclear gradient. European Journal of Cell Biology 63 255-268
Beattie JH and Kwun IS (2004) Is zinc deficiency a risk factor for atherosclerosis? British Journal of Nutrition 91 177-181
Beaton A, Broadhurst MK, Wilkins RJ, Wheeler TT (2003) Suppression of beta-casein gene expression by inhibition of protein synthesis in mouse mammary epithelial cells is associated with stimulation of NF-kB activity and blockage of prolactin-Stat5 signaling. Cell and Tissue Research 311 207-215
Beauparlant P and Hiscott J (1996) Biological and biochemical inhibitors of the NF-kB/Rel proteins and cytokine synthesis. Cytokine & Growth Factor Reviews 7 175-190
Beauparlant P, Kwan I, Bitar R, Chou R, Koromilas AE, Sonenberg N and Hiscott J (1994) Disruption of IkBa regulation by antisense RNA expression leads to malignant transformation. Oncogene 9 3189-3197
Beauparlant P, Kwon H, Clarke M, Lin R, Sonenberg N, Wainberg M and Hiscott J (1996) Transdominant mutants of IkBa block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication. Journal of Virology 70 5777-5785
Beauparlant P, Lin R and Hiscott J (1996) The role of the C-terminal domain of IkBa in protein degradation and stability. Journal of Biological Chemistry 271 10690-10696
Becaria A, Bondy SC and Campbell A (2003) Aluminum and copper interact in the promotion of oxidative but not inflammatory events: Implications for Alzheimer’s disease. Journal of Alzheimers Disease 5 31-38
Beck JF and Kroemer HK (2004) Nuclear Factor-kB mediates up-regulation of cathepsin B by doxorubicin in tumor cells. Molecular Pharmacology 65 1092-1102
Beck G, Yard BA, Schulte J, Oberacker R, van Ackern K, van Der Woude FJ, Krimsky M, Kaszkin M and Yedgar S (2002) Inhibition of LPS-induced chemokine production in human lung endothelial cells by lipid conjugates anchored to the membrane. British Journal of Pharmacology 135 1665-1674
Beck GC, Rafat N, Brinkkoetter P, Hanusch C, Schulte J, Haak M, van Ackern K, Van der Woude FJ and Yard BA (2006) Heterogeneity in lipopolysaccharide responsiveness of endothelial cells identified by gene expression profiling: role of transcription factors. Clinical and Experimental Immunology 143 523-533
Beck IM, Vanden Berghe W, Vermeulen L, Bougarne N, Vander Cryssen B, Haegeman G and De Bosscher K (2008) Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kB inhibition. EMBO Journal in press
Beck V, Rohr U and Jungbauer A (2005) Phytoestrogens derived from red clover: An alternative to estrogen replacement therapy? Journal of Steroid Biochemistry and Molecular Biology 94 499-518
Beck Z, Bacsi A, Liu X, Ebbesen P, Andirko I I, Csoma E, Konya J, Nagy E and Toth FD (2003) Differential patterns of human cytomegalovirus gene expression in various T-cell lines carrying human T-cell leukemia-lymphoma virus type I: Role of tax-activated cellular transcription factors. Journal of Medical Virology 71 94-104
Beck-Schimmer B, Rosenberger DS, Neff SB, Jamnicki M, Suter D, Fuhrer T, Schwendener R, Booy C, Reyes L, Pasch T and Schimmer RC (2005) Pulmonary aspiration: new therapeutic approaches in the experimental model. Anesthesiology103 556-566
Becker C, Barbulescu K, Wirtz S, Mey zum Büschednfelde K-H, Pettersson S and Neurath MF (1999) Constitutive and inducible in vivo protein/DNA interactions at the tumor necrosis factor-alpha promoter in primary T lymphocytes. Gene Expression 8 115-127
Becker C, Wirtz S, Blessing M, Pirhonen J, Strand D, Bechthold O, Frick J, Galle PR, Autenrieth I and Neurath MF (2003) Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. Journal of Clinical Investigation 112 693-706
Becker I, Salaiza N, Aguirre M, Delgado J, Carrillo-Carrasco N, Kobeh LG, Ruiz A, Cervantes R, Torres AP, Cabrera N, Gonzalez A, Maldonado C and Isibasi A (2003) Leishmania lipophosphoglycan (LPG) activates NK cells through toll-like receptor-2. Molecular and Biochemical Parasitology 130 65-74
Becker MN, Sauer MS, Muhlebach MS, Hirsh AJ, Wu Q, Verghese MW and Randell SH (2003) Cytokine secretion by cystic fibrosis airway epithelial cells. American Journal of Respiratory Critical Care Medicine 169 645-653
Becker TM, Rizos H, de la Pena A, Leclercq IA, Woodruff S, Kefford RF and Mann GJ (2005) Impaired inhibition of NF-kB activity by melanoma-associated p16INK4a mutations. Biochemical and Biophysical Research Communications 332 873-879
Becker-Herman S, Arie G, Medvedovsky H, Kerem A and Shachar I (2005) CD74 is a member of the regulated intramembrane proteolysis (RIP)-processed protein family. Molecular Biology of the Cell 16 5061-5069
Becue A, Meurice N, Leherte L and Vercauteren DP (2003) Description of protein-DNA complexes in terms of electron-density topological features. Acta Crystallogr D Biol Crystallogr 59 2150-2162
Becuwe P, Bianchi A, Didelot C, Barberi-Heyob M and Dauca M (2003) Arachidonic acid activates a functional AP-1 and an inactive NF-kB complex in human HepG2 hepatoma cells. Free Radic Biol Med 35 636-647
Becuwe P, Bianchi A, Keller JM and Dauca M (1999) Effects of the peroxisome proliferator clofibric acid on superoxide dismutase expression in the human HepG2 hepatoma cell line. Biochemical Pharmacology 58 1025-1033
Becuwe P and Dauca M (2005) Comparison of cytotoxicity induced by hypolipidemic drugs via reactive oxygen species in human and rodent liver cells. International Journal of Molecular Medicine 16 483-492
Bednarik DP, Duckett C, Kim SU, Perez VL, Griffis K, Guenthner PC and Folks TM (1991) DNA CpG methylation inhibits binding of NF-kB proteins to the HIV-1 long terminal repeat cognate DNA motifs. New Biologist 3 969-976
Bednarski BK, Ding X, Coombe K, Baldwin AS and Kim HJ (2008) Active roles for inhibitory kB kinases alpha and beta in nuclear factor-kB-mediated chemoresistance to doxorubicin. Molecular Cancer Therapeutics 7 1827-1835
Bedoya F, Sandler LL and Harton JA (2007) Pyrin-only protein 2 modulates NF-kB and disrupts ASC:CLR interactions. Journal of Immunology 178 3837-3845
Bedoya LM, Beltran M, Sancho R, Olmedo DA, Sanchez-Palomino S, Del Olmo E, Lopez-Perez JL, Munoz E, Feliciano AS and Alcami J (2005) 4-Phenylcoumarins as HIV transcription inhibitors. Bioorganic Medicinal Chemistry Letters 15 4447-4450
Bedoya LM, Del Olmo E, Sancho R, Barboza B, Beltran M, Garcia-Cadenas AE, Sanchez-Palomino S, Lopez-Perez JL, Munoz E, Feliciano AS and Alcami J (2006) Anti-HIV activity of stilbene-related heterocyclic compounds. Bioorganic and Medicinal Chemistry Letters 16 4075-4079
Beech JT, Andreakos E, Ciesielski CJ, Green P, Foxwell BM and Brennan FM (2006) T cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NF-kB: implications for rheumatoid arthritis.
Arthritis Research and Therapy 8 R168
Beere HM (2004) ‘The stress of dying’: the role of heat shock proteins in the regulation of apoptosis. Journal of Cell Science 117 2641-2651
Beere HM (2005) Death versus survival: functional interaction between the apoptotic and stress-inducible heat shock protein pathways. Journal of Clinical Investigation 115 2633-2639
Beers A, Haas MJ, Wong NC and Mooradian AD (2006) Inhibition of Apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling. Biochemistry 45 2408-2413
Beg AA (2004) ComPPARtmentalizing NF-kB in the gut. Nature Immunology 5 14-16
Beg AA and Baldwin Jr AS (1993) The IkB proteins: multifunctional regulators of Rel/NF-kB transcription factors. Genes & Development 7 2064-2070
Beg AA and Baldwin Jr AS (1994) Activation of multiple NF-kB/Rel DNA-binding complexes by tumor necrosis factor. Oncogene 9 1487-1492
Beg AA and Baltimore D (1996) An essential role for NF-kB in preventing TNF-a-induced cell death. Science 274 782-784
Beg AA, Finco TS, Nantermet PV and Baldwin Jr AS (1993) Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IkBa: a mechanism for NF-kB activation. Molecular and Cellular Biology 13 3301-3310
Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA and Baldwin Jr AS (1992) IkB interacts with the nuclear localization sequences of the subunits of NF-kB: a mechanism for cytoplasmic retention. Genes & Development 6 1899-1913
Beg AA, Sha WC, Bronson RT and Baltimore D (1995) Constitutive NF-kB activation, enhanced granulopoiesis and neonatal lethality in IkBa deficient mice. Genes & Development 9 2736-2746
Beg AA, Sha WC, Bronson RT, Ghosh S and Baltimore D (1995) Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kB. Nature 376 167-170
Begni S, Moraschi S, Bignotti S, Fumagalli F, Rillosi L, Perez J and Gennarelli M (2003) Association between the G1001C polymorphism in the GRIN1 gene promoter region and schizophrenia. Biol Psychiatry 53 617-619
Begon E, Michel L, Flageul B, Beaudoin I, Jean-Louis R, Bachelez H, Dubertret L and Musette P (2007) Expression, subcellular localization and cytokinic modulation of Toll-like receptors (TLRs) in normal human keratinocytes: TLR2 up-regulation in psoriatic skin. European Journal of Dermatology 17 497-506
Begue B, Wajant H, Bambou JC, Dubuquoy L, Siegmund D, Beaulieu JF, Canioni D, Berrebi D, Brousse N, Desreumaux P, Schmitz J, Lentze MJ, Goulet O, Cerf-Bensussan N and Ruemmele FM (2006) Implication of TNF-related apoptosis-inducing ligand in inflammatory intestinal epithelial lesions. Gastroenterology 1301962-1974
Behl C (1999) Vitamin E and other antioxidants in neuroprotection. International Journal of Vitamin & Nutrition Research 69 213-219
Behl C, Davis JB, Lesley R and Schubert D (1994) Hydrogen peroxide mediates amyloid b protein toxicity. Cell 77 817-827
Behzad AR, Morimoto K, Gosselink J, Green J, Hogg JC and Hayashi S (2006) Induction of mesenchymal cell phenotypes in lung epithelial cells by adenovirus E1A. European Respiratory Journal 28 1106-1116
Beidelschies MA, Huang H, McMullen MR, Smith MV, Islaam AS, Goldberg VM, Chen X, Hagy LE and Greenfield EM (2008) Stimulation of macrophage TNFa production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kB pathways but is independent of p38 and JNK. Journal of Cellular Physiology in press
Beier CP, Wischhusen J, Gleichmann M, Gerhardt E, Pekanovic A, Krueger A, Taylor V, Suter U, Krammer PH, Endres M, Weller M and Schulz JB (2005) FasL (CD95L/APO-1L) resistance of neurons mediated by phosphatidylinositol 3-kinase-Akt/protein kinase B-dependent expression of lifeguard/neuronal membrane protein 35. Journal of Neuroscience 25 6765-6774
Beier UH, Holtmeier C, Weise JB and Gorogh T (2007) Fibronectin suppression in head and neck cancers, inflammatory tissues and the molecular mechanisms potentially involved. International Journal of Oncology 30 621-629
Beigi RD, Kertesy SB, Aquilina G and Dubyak GR (2003) Oxidized ATP (oATP) attenuates proinflammatory signaling via P2 receptor-independent mechanisms. British Journal of Pharmacology 140 507-519
Beinke S, Belich MP and Ley SC (2002) The death domain of NF-kB1 p105 is essential for signal-induced p105 proteolysis. Journal of Biological Chemistry 277 24162-24168
Beinke S, Deka J, Lang V, Belich MP, Walker PA, Howell S, Smerdon SJ, Gamblin SJ and Ley SC (2003) NF-kB1 p105 negatively regulates TPL-2 MEK kinase activity. Molecular and Cellular Biology 23 4739-4752
Beinke S and Ley SC (2004) Functions of NF-kB1 and NF-kB2 functions in immune cell biology. Biochem J 382 393-409
Beinke S, Robinson MJ, Hugunin M and Ley SC (2004) Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkB kinase-induced proteolysis of NF-kB1 p105. Molecular and Cellular Biology 24 9658-9667
Beisner DR, Ch’en IL, Kolla RV, Hoffmann A and Hedrick SM (2005) Innate immunity conferred by B cells is regulated by caspase-8. Journal of Immunology 175 3469-3473
Beisser PS, Verzijl D, Gruijthuijsen YK, Beuken E, Smit MJ, Leurs R, Bruggeman CA and Vink C (2005) The Epstein-Barr Virus BILF1 gene encodes a G protein-coupled receptor that inhibits phosphorylation of RNA-dependent protein kinase. Journal of Virology 79 441-449
Beisswenger C, Platz J, Seifart C, Vogelmeier C and Bals R (2004) Exposure of differentiated airway epithelial cells to volatile smoke in vitro. Respiration 71 402-409
Belaiba RS, Bonello S, Zahringer C, Schmidt S, Hess J, Kietzmann T and Gorlach A (2007) Hypoxia up-regulates HIF-1alpha transcription by involving PI-3 kinase and NFkB in pulmonary artery smooth muscle cells. Molecular Biology of the Cellin press
Belaiba RS, Djordjevic T, Bonello S, Artunc F, Lang G, Hess J and Gorlach A (2006) The serum- and glucocorticoid-inducible kinase Sgk-1 is involved in pulmonary vascular remodeling. Role in redox-sensitive regulation of tissue factor by thrombin. Circulation Research 98 828-836
Belcher JD, Bryant CJ, Nguyen J, Bowlin PR, Kielbik MC, Bischof JC, Hebbel RP and Vercellotti GM (2003) Transgenic sickle mice have vascular inflammation. Blood 101 3953-3959
Belcher JD, Mahaseth H, Welch TE, Vilback AE, Sonbol KM, Kalambur VS, Bowlin PR, Bischof JC, Hebbel RP and Vercellotti GM (2005) Critical role of endothelial cell activation in hypoxia-induced vaso-occlusion in transgenic sickle mice. American Journal of Physiology: Heart and Circulatory Physiology 288 H2715-H2725
Belcher JD, Mahaseth H, Welch TE, Otterbein LE, Hebbel RP and Vercellotti GM (2006) Hemo oxygenase-1 is a modulator of inflammatina nd vaso-occlusion in transgenic sickle mice. Journal of Clinical Investigation 116 808-816
Belguise K, Guo S and Sonenshein GE (2007) Activation of FOXO3a by the green tea polyphenol epigallocatechin-3-gallate induces estrogen receptor alpha expression reversing invasive phenotype of breast cancer cells. Cancer Research 67 5763-5770
Belguise K, Guo S, Yang S, Rogers AE, Seldin DC, Sherr DH and SOnenshein GE (2007) Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype. Cancer Research 67 11742-11750
Belguise K and Sonenshein GE (2007) PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis. Journal of Clinical Investigation in press
Belibasakis GN, Bostanci N, Hashim A, Johansson A, Aduse-Opoku J, Curtis MA and Hughes FJ (2007) Regulation of RANKL and OPG gene expression in human gingival fibroblasts and periodontal ligament cells by Porphyromonas gingivalis: A putative role of the Arg-gingipains. Microbial Pathogensis 43 46-53
Belich M, Salmerón A, Johnston LH and Ley SC (1999) TPL-2 kinase regulates the proteolysis of the NF-kB-inhibitory protein NF-kB1 p105. Nature 397 363-368
Bell S, Matthews JR, Jaffray E and Hay RT (1996) IkBg inhibits DNA binding of NF-kB p50 homodimers by interacting with residues that contact DNA. Molecular and Cellular Biology 16 6477-6485
Bell SA, Page S, Baumgartner B, Berking C, Haas M, Eisele T, Neumeier D and Brand K (1999) Involvement of Nuclear Factor-kB in a murine model for the acute form of autoimmune-like toxic oil syndrome. Toxicology and Applied Pharmacology 157 213-221
Bellas RE and Li Y (1996) A block to efficient replication of simian immunodeficiency virus in C8166 cells can be overcome by duplication of the NF-kB binding site. Journal of Biochemical Sciences 3 415-421
Bellido C, Lopez-Miranda J, Blanco-Colio LM, Perez-Martinez P, Muriana FJ, Martin-Ventura JL, Marin C, Gomez P, Fuentes F, Egido J and Perez-Jimenez F (2004) Butter and walnuts, but not olive oil, elicit postprandial activation of nuclear transcription factor kB in peripheral blood mononuclear cells from healthy men. American Journal of Clinical Nutrition 80 1487-1491
Bellocq A, Israel-Biet D, Cadranel J, Perez J, Fouqueray B, Kanfer A, Girot R and Baud L (1999) Reduction of tumour necrosis factor alpha expression and signalling in peripheral blood mononuclear cells from patients with thalassaemia or sickle cell anaemia upon treatment with desferrioxamine. Cytokine 11 168-172
Bellarosa D, Binaschi M, Maggi CA and Goso C (2005) Sabarubicin- (MEN 10755) and paclitaxel show different kinetics in nuclear factor-kB (NF-kB) activation: effect of parthenolide on their cytotoxicity. Anticancer Research 25 2119-2128
Bellas RE and Sonenshein GE (1999) Nuclear factor kB cooperates with c-Myc in promoting murine hepatocyte survival in a manner independent of p53 tumor suppressor function. Cell Growth & Differentiation 10 287-294
Bellas RE, FitzGerald MJ, Fausto N and Sonenshein GE (1997) Inhibition of NF-kB activity induces apoptosis in murine hepatocytes. American Journal of Pathology 151 891-896
Bellas RE, Hopkins N and Li Y (1993) The NF-kB binding site is necessary for efficient replication of simian immunodeficiency virus of macaques in primary macrophages but not in T cells in vitro. Journal of Virology 67 2908-2913
Bellas RE, Lee JS and Sonenshein GE (1995) Expression of constitutive NF-kB-like activity is essential for proliferation of cultured bovine vascular smooth muscle cells. Journal of Clinical Investigation 96 2521-2527
Bellavia D, Campese AF, Vacca A, Gulino A and Screpanti I (2003) Notch3, another Notch in T cell development. Seminars in Immunology 15 107-112
Bellon M and Nicot C (2008) Central role of PI3K in transcriptional activation of hTERT in HTLV-I infected cells. Blood in press
Bellosta S, Baetta R, Canavesi M, Comparato C, Granta A, Monetti M, Cairoli F, Eberini I, Publisi L and Corsini A (2007) Raloxifene inhibits matrix metalloproteinases expression and activity in macrophages and smooth muscle cells. Pharmacological Research in press
Belt AR, Baldassare JJ, Molnar M, Romero R and Hertelendy F (1999) The nuclear transcription factor NF-kB mediates interleukin-1beta-induced expression of cyclooxygenase-2 in human myometrial cells. American Journal of Obstetrics and Gynecology 181 359-366
Beltran JA, Peek J and CHang SL (2006) Expression and regulation of the mu opioid peptide receptor in TPA-differential HL-60 promyelocytic leukemia cells. Internatioanl Immunopharmacology 6 1331-1340
Beltz LA, Bayer DK, Moss AL and Simet IM (2006) Mechanisms of cancer prevention by green and black tea polyphenols. Anticancer Agents in Medicinal Chemistry 6 389-406
Ben-Neriah Y (2002) Regulatory functions of ubiquitination in the immune system. Nature Immunology 3 20-26
Ben-Neriah Y (2003) Pinning NF-kB to the nucleus. Molecular Cell 12 1344-1345
Ben-Neriah Y and Schmidt-Supprian M (2007) Epithelial NF-kB maintains host gut microflora homeostasis. Nature Immunology 8 479-481
Ben-Neriah Y and Schmitz ML (2004) Of mice and men. EMBO Reports 5 668-673
Ben-Othman R, Guizani-Tabbane L and Dellagi K (2008) Leishmania initially activates but subsequently down-regulates intracellular mitogen-activated protein kinases and nuclear factor-kB signaling in macrophages. Molecular Immunology in press
Benatar T, Iacampo S, Tkalec L and Ratcliffe MJ (1991) Expression of immunoglobulin genes in the avian embryo bone marrow revealed by retroviral transformation. European Journal of Immunology 21 2529-2536
Benatar T, Tkalec L and Ratcliffe MJ (1992) Stochastic rearrangement of immunoglobulin variable-region genes in chicken B cell development. Proceedings of the National Academy of Sciences USA 89 7615-7619
Benayoun B, Baghdiguian S, Lajmanovich A, Baartoli M, Daniele N, Gicquel E, Bourg N, Raynaud F, Pasquier MA, Suel L, Lochmuller H, Lefranc G and Richard I (2007) NF-kB-dependent expression of the antiapoptotic factor c-FLIP is regulated by calpain 3, the protein involved in limb-girdle muscular dystrophy type 2A. FASEB Journal in press
Benchimol E, Seow CH, Steinhart A and Griffiths A (2008) Traditional corticosteroids for induction of remission in Crohn’s disease. Cochrane Database Systems Review 16 CD006792
Bendall HH, Scherer DC, Edson CR, Ballard DW and Moltz E (1997) Transcription factor NF-kB regulates inducible Oct-2 gene expression in precursor B lymphocytes. Journal of Biological Chemistry 272 28826-28828
Bendall HH, Sikes ML and Oltz EM (2001) Transcription factor NF-kB regulates Ig lambda light chain gene rearrangement. Journal of Immunology 167 264-269
Bendall HH, Sikes ML, Ballard DW and Oltz EM (1999) An intact NF-kB signaling pathway is required for maintenance of mature B cell subsets. Molecular Immunology 36 187-195
Benedict CA, Angulo A, Patterson G, Ha S, Huang H, Messerle M, Ware CF and Ghazal P (2004) Neutrality of the canonical NF-kB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro. Journal of Virology 78 741-750
Benedict CA and Ware CF (2001) Virus targeting of the tumor necrosis factor superfamily. Virology 289 1-5
Benedict CA, Banks TA, Senderowicz L, Ko M, Britt WJ, Angulo A, Ghazal P and Ware CF (2001) Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus detente. Immunity 15 617-626
Benedyk M, Sopalla C, Nacken W, Bode G, Melkonyan H, Banfi B and Kerkhoff C (2007) HaCaT keratinocytes overexpressing the S100 proteins S100A8 and S100A9 show increased NADPH oxidase and NF-kB activities. Journal of InvestigativeDermatology in press
Benezra M, Chevallier N, Morrison DJ, MacLachlan TK, El-Deiry WS and Licht JD (2003) BRCA1 augments transcription by the NF-kB transcription factor by binding to the Rel domain of the p65/RelA subunit. Journal of Biological Chemistry 278 26333-26341
Bengmark S (2006) Curcumin, an atoxic antioxidant and natural NFkB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. Japenese Journal of Parenteral andEnteral Nutrition 30 45-51
Bengmark S (2007) Advanced glycation and lipoxidation end products amplifiers of inflammation: the role of food. JPEN J Parenter Enteral Nutr 31 430-440
Bengmark S and Hajdu N (2008) Endproducts and receptor of advanced glycation and lipoxidation (AGE, ALE, RAGE) and chronic diseases – a food perspective [Article in Hungarian]. Orv Hetil 149 771-778
Benhamou LE, Watanabe T, Kitamura D, Cazenave P-A and Sarthou P (1994) Signaling properties of anti-immunoglobulin-resistant variants of WEHI-231 B lymphoma cells. European Journal of Immunology 24 1993-1999
Beni SM, Kohen R, Reiter RJ, Tan DX and Shohami E (2003) Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kB and AP-1. FASEB Journal 18 149-151
Beni SM, Tsenter J, Alexandrovich AG, Galron-Krool N, Barzilai A, Kohen R, Grigoriadis N, Simeonidou C and SHomani E (2005) CuZn-SOD deficiency, rather than overexpression, is associated with enhanced recovery and attenuated activation of NF-kB after brain trauma in mice. Journal of Cerebral Blood Flow and Metabolism 26 478-490
Benimetskaya L, Miller P, Benimetsky S, Maciaszek A, Guga P, Beaucage SL, Wilk A, Grajkowski A, Halperin AL, Stein CA (2001) Inhibition of potentially anti-apoptotic proteins by antisense protein kinase C-alpha (Isis 3521) and antisense bcl-2 (G3139) phosphorothioate oligodeoxynucleotides: relationship to the decreased viability of T24 bladder and PC3 prostate cancer cells. Molecular Pharmacology 60 1296-1307
Benitah SA, Valeron PF and Lacal JC (2003) ROCK and nuclear factor-kB-dependent activation of cyclooxygenase-2 by Rho GTPases: effects on tumor growth and therapeutic consequences. Molecular Biology of the Cell 14 3041-3054
Benito MJ, Murphy E, Murphy EP, Van Den Berg WB, FitzGerald O and Bresnihan B (2004) Increased synovial tissue NF-kB1 expression at sites adjacent to the cartilage-pannus junction in rheumatoid arthritis. Arthritis & Rheumatism 50 1781-1787
Benito MJ, Veale DJ, Fitzgerald O, van den Berg WB nad Bresnihan B (2005) Synovial tissue inflammation in early and late osteoarthritis. Annals of Rheumatoid Disease 64 1263-1267
Benjamin CL, Jenster G and Piedrahita JA (2004) Use of artificial androgen receptor coactivators to alter myoblast proliferation. Journal of Steroid Biochemistry and Molecular Biology 91 111-119
Bennasser Y, Badou A, Takaczuk J and Bahraoui E (2002) Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-a. Virology 303 174-180
Bennett BL, Lacson RG, Chen CC, Cruz R, Wheeler JS, Kletzien RF, Tomasselli AG, Heinrikson RL and Manning AM (1996) Identification of signal-induced IkB-a kinases in human endothelial cells. Journal of Biological Chemistry 271 19680-19688
Bennett MJ and Eisenberg D (2004) The evolving role of 3D domain swapping in proteins. Structure (Cambridge) 12 1339-1341
Bennett RL, Blalock WL, Abtahi DM, Pan Y, MOyer SA and May WS (2006) RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawl, chemotherapy and viral infection. Blood 108 821-829
Bennett V (1992) Ankryins: adaptors between diverse plasma membrane proteins and the cytoplasm. Journal of Biological Chemistry 267 8703-8706
Benoit GR, Flexor M, Besancon F, Altucci L, Rossin A, Hillion J, Balajthy Z, Legres L, Segal-Bendirdjian E, Gronemeyer H and Lanotte M (2001) Autonomous rexinoid death signaling is suppressed by converging signaling pathways in immature leukemia cells. Molecular Endocrinology 15 1154-1169
Benoit V, Chariot A, Delacroix L, Deregowski V, Jacobs N, Merville MP and Bours V (2004) Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappaB through c-FLIP-L expression. Cancer Research 64 2684-2691
Benoit V, de Moraes E, Dar NA, Taranchon E, Bours V, Hautefeuille A, Taniere P, Chariot A, Scoazec JY, de Moura Gallo CV, Merville MP and Hainaut P (2006) Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kB. Oncogene 25 5708-5718
Benoit V, Hellin A-C, Huygen S, Gielen J, Bours V and Merville M-P (2000) Additive effect between NF-kB subunits and p53 protein for transcriptional activation of human p53 promoter. Oncogene 19 4787-4794
Bensaude E, Turner JL, Wakeley PR, Sweetman DA, Pardieu C, Drew TW, Wileman T and Powell PP (2004) Classical swine fever virus induces proinflammatory cytokines and tissue factor expression and inhibits apoptosis and interferon synthesis during the establishment of long-term infection of porcine vascular endothelial cells. Journal of General Virology 85 1029-1037
Benson RJ, Hostager BS and Bishop GA (2006) Rapid CD40-mediated rescue from CD95-induced apoptosis requires TNFR-associated factor-6 and PI3K. EuropeanJournal of Immunology 36 2535-2543
Bentirez-Alj M, Barbu V, Fillet M, Chariot A, Relic B, Jacobs N, Gielen J, Merville M-P and Bours V (2003) NF-kB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene 22 90-97
Bentires-Alj M, Dejardin E, Viatour P, Van Lint C, Froesch B, Reed JC, Merville MP and Bours V (2001) Inhibition of the NF-kB transcription factor increases Bax expression in cancer cell lines. Oncogene 20 2805-2813
Bentires-Alj M, Hellin A-C, Ameyar M, Chouaib S, Merville M-P and Bours V (1999) Stable inhibition of nuclear factor kB in cancer cells does not increase sensitivity to cytotoxic drugs. Cancer Research 59 811-815
Bentley K, Deacon N, Sonza S, Zeichner S and Churchill M (2004) Mutational analysis of the HIV-1 LTR as a promoter of negative sense transcription. Archives of Virology 149 2277-2294
Benz D, Cadet P, Mantione K, Zhu W and Stefano G (2002) Tonal nitric oxide and health – a free radical and a scavenger of free radicals. Medical Science Monitor 8 RA1-RA4
Beppu K, Morisaki T, Matsunaga H, Uchiyama A, Ihara E, Hirano K, Kanaide H, Tanaka M and Katano M (2003) Inhibition of interferon-gamma-activated nuclear factor-kappaB by cyclosporin A: a possible mechanism for synergistic induction of apoptosis by interferon-gamma and cyclosporin A in gastric carcinoma cells. Biochemical and Biophysical Research Communications 305 797-805
Beppu M, Ikebe T and Shirasuna K (2002) The inhibitory effects of immunosuppressive factors, dexamethasone and interleukin-4, on NF-kB-mediated protease production by oral cancer. Biochimica et Biophysica Acta 1586 11-22
Beramendi A, Peron S, Megighian A, Reggiani C and Cantera R (2005) The inhibitor kappaB-ortholog Cactus is necessary for normal neuromuscular function in Drosophila melanogaster. Neuroscience 134 397-406
Beranek JT (2002) Sesquiterpene lactone parthenolide, an inhibitor of IkB kinase complex and nuclear factor-kB, exerts beneficial effects in myocardial reperfusion injury. Shock 17 127-134
Béraud C, Henzel WJ and Baeuerle PA (1999) Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kB activation. Proceedings of the National Academy of Sciences USA 96 429-434
Béraud C, Sun S-C, Ganchi P, Ballard DW and Greene WC (1994) Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kB2 p100 gene product: implications for viral latency. Molecular and Cellular Biology 14 1374-1382
Beraza N, Ludde T, Assmus U, Roskams T, Borght SV and Trautwein C (2007) Hepatocyte-specific IKKg/NEMO expression determines the degree of liver injury.Gastroenterology 132 2504-2517
Beraza N, Malato Y, Vander Borght S, Liedtke C, Wasmuth HE, Dreano M, de Vox R, Roskams T and Trauwein C (2008) Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis. Gut 57 655-663
Berbaum K, Shanmugam K, Stuchbury G, Wiede F, Korner H aand Munch G (2007) Induction of novel cytokines and chemokines by advanced glycation endproducts determined with a cytometric bead array. Cytokine in press
Berberich I, Shu GL and Clark EA (1994) Cross-linking CD40 on B cells rapidly activates nuclear factor-kB. Journal of Immunology 153 4357-4366
Berche P (2003) Bacterial aggression [Article in French]. Ann Pharm Fr 61 270-275
Berchtold CM, Chen KS, Miyamoto S and Gould MN (2005) Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kB pathway. Cancer Research 65 8558-8566
Berchtold CM, Wu Z, Huang TT and Miyamoto S (2006) Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. Molecular and CellularBiology in press
Berchtold S, Muhl-Zurbes P, Maczek E, Golka A, Schuler G and Steinkasserer A(2002) Cloning and characterization of the promoter region of the human CD83 gene. Immunobiology 205 231-246
Berclaz PY, Carey B, Fillipi MD, Wernke-Dollries K, Geraci N, Cush S, Richardson T, Kitzmiller J, O’Connor M, Hermoyian C, Korfhagen T, Whitsett JA and Prapnell BC (2006) GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. American Journal of Respiratory Cell and Molecular Biology in press
Berenson JR, Ma HM and Vescio R (2001) The role of nuclear factor-kB in the biology and treatment of multiple myeloma. Seminars in Oncology 28 626-633
Beretta A, Clerici M, Hasson H, Fumagalli L, Trabattoni D, Lillo F, Ferrante P, Saniabadi AR, Adachi M and Lazzarin A (2000) Ex-vivo purging of circulating monocytes results in immunovirologic improvement in partially HAART responder HIV-infected patients. J Biol Regul Homeost Agents 14 27-31
Berenbaum F (2004) Signaling transduction: target in osteoarthritis. Current Opinions in Rheumatology 16 616-622
Berg AH, Lin Y, Lisanti MP and Scherer PE (2004) Adipocyte differentiation induces dynamic changes in NFkB expression and activity. American Journal of Physiology, Endocrinology and Metabolism 287 E1178-E1188
Berg EL, Kunkel EJ, Hytopoulos E and Plavec I (2006) Characterization of compound mechanisms and secondary activities by BioMAP analysis. Journal of Pharmacological and Toxicological Methods 53 67-74
Berger N, Ben Bassat H, Klein BY and Laskov R (2007) Cytotoxicity of NF-kB inhibitors Bay 11-7085 and caffeic acid phenethyl ester to Ramos and other human B-lymphoma cell lines.
Experimental Hematology 35 1495-1509
Bergeron M and Olivier M (2006) Trypanosoma cruzi-mediated IFN-g-inducible nitric oxide output in macrophages is regulated by iNOS mRNA stability. Journal of Immunology 177 6271-6280
Berges C, Naujokat C, Tinapp S, Wieczorek H, Hoh A, Sadeghi M, Opelz G and Daniel V (2005) A cell line model for the differentiation of human dendritic cells. Biocehmical Biophysical Research Communications 333 896-907
Berghe WV, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W and Gaegeman G (1998) p38 and extracellular singnal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kB p65 transactivation mediated by tumor necrosis factor. Journal of Biological Chemistry 273 3285-3290
Bergmann A (2006) IKK signaling: not just NF-kB. Current Biology 16 R588-R590
Bergmann M, Hart L, Lindsay M, Barnes PJ and Newton R (1998) IkBa degradation and nuclear factor-kB DNA binding are insufficient for interleukin-1b and tumor necrosis factor-a-induced kB-dependent transcription: requirement for an additional activation pathway. Journal of Biological Chemistry 273 6607-6610
Bergmann MW, Loser P, Dietz R and v Harsdorf R (2001) Effect of NF-kB inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes. Journal of Molecular and Cellular Cardiology 33 1223-1232
Bergmann MW, Rechner C, Freund C, Baurand A, El Jamali A and Dietz R (2004) Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin. Journal of Molecular and Cellular Cardiology 37 681-690
Bergmann MW, Staples KJ, Barnes PJ and Newton R (2004) Nuclear factor-kB does not mediate the inhibitory effects of dexamethasone on granulocyte-macrophage colony-stimulating factor expression. Immunology 111 430-434
Bergmann MW, Staples KJ, Smith SJ, Barnes PJ and Newton R (2004) Glucocorticoid inhibition of GM-CSF from T cells is independent of control by NF-kB and CLE0. Am J Respir Cell Mol Biol 30 555-563
Bergqvist S, Croy CH, Kjaergaard M, Huxford T, Ghsoh G and Komives EA (2006) Thermodynamics reveal that helix four in the NLS of NF-kB p65 anchors IkBa, forming a very stable complex. Journal of Molecular Biology 360 421-434
Berin MC, Darfeuille-Michaud A, Egan LJ, Miyamoto Y and Kagnoff MF (2002) Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kB and MAP kinase pathways and the upregulated expression of interleukin 8. Cellular Microbiology 4 635-648
Berin MC, Dwinell MB, Eckmann L and Kagnoff MF (2001) Production of MDC/CCL22 by human intestinal epithelial cells. American Journal of Physiology: Gastrointestinal Liver Physiology 280 G1217-G1226
Berkowitz B, Huang DB, Chen-Park FE, Sigler PB and Ghosh G (2002) The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the IFNbeta kB site. Journal of Biological Chemistry 277 24694-24700
Berlier W, Cremel M, Hamzeh H, Levy R, Lucht F, Bourlet T, Possetto B and Delezay O (2006) Seminal plasma promotes the attraction of Langerhans cells via the secretion of CCL20 by vaginal epithelial cells: involvement in the sexual transmission of HIV. Human Reproduction 21 1135-1142
Berlin AL, Paller AS and Chan LS (2002) Incontinentia pigmenti: A review and update on the molecular basis of pathophysiology. Journal of the American Academy of Dermatology 47 169-187
Berlin AL, Paller AS and Chan LS (2002) Incontinentia pigmenti: A review and update on the molecular basis of pathophysiology. Journal of the American Academy of Dermatology 47 169-187
Berman KS (2003) Aspirin and the prevention of colon cancer. New England Journal of Medicine 348 2466-2467
Bernal A, Pastore RD, Asgary Z, Keller SA, Cesarman E, Liou HC and Schattner EJ (2001) Survival of leukemic B cells promoted by engagement of the antigen receptor. Blood 98 3050-3057
Bernal-Mizrachi L, Lovly CM and Raner L (2006) The role of NF-kB-1 and NF-kB-2-mediated resistance to apoptosis in lymphomas. Proceedings of the NationalAcademy of Sciences USA 103 9220-9225
Bernal-Mizrachi E, Wen W, Shornick M and Permutt MA (2002) Activation of nuclear factor-kappaB by depolarization and Ca(2+) influx in MIN6 insulinoma cells. Diabetes 51 S484-S488
Bernard D, Gosselin K, Monte D, Vercamer C, Bouali F, Pourtier A, Vandenbunder B and Abbadie C (2004) Involvement of Rel/nuclear factor-kB transcription factors in keratinocyte senescence. Cancer Research 64 472-481
Bernard D, Mont D, Vandenbunder B, Abbadie C (2001) Involvement of rel/nf-kB transcription factors in cellular senescence. ScientificWorldJournal 1 67
Bernard D, Monte D, Vandenbunder B and Abbadie C (2002) The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD. Oncogene 21 4392-4402
Bernard D, Monte D, Vandenbunder B and Abbadie C (2002) The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD. Oncogene 21 4392-4402
Bernard D, Quatannens B, Begue A, Vandenbunder B and Abbadie C (2001) Antiproliferative and antiapoptotic effects of crel may occur within the same cells via the up-regulation of manganese superoxide dismutase. Cancer Research 61 2656-2664
Bernard D, Quatannens B, Vandenbunder B and Abbadie C (2001) Rel/NF-kB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. Journal of Biological Chemistry 276 27322-27328
Bernard D, Slomianny C, Vandenbunder B and Abbadie C (2001) cRel induces mitochondrial alterations in correlation with proliferation arrest. Free Radical Biology and Medicine 31 943-953
Bernardo A, Levi G and Minghetti L (2000) Role of the peroxisome proliferator-activated receptor-gamma (PPAR- gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions. European Journal of Neuroscience 12 2215-2223
Bernasconi D, Amici C, La Frazia S, Ianaro A and Santoro MG (2005) The IkB kinase is a key factor in triggering influenza A virus-induced inflammatory cytokines production in airway epithelial cells. Journal of Biological Chemistry 280 24127-24134
Berndt C, Lillig CH and Holmgren A (2007) Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. American Journal of Physiology: Heart and CirculatoryPhysiology 292 H1227-H1236
Berndt U, Bartsch S, Philipsen L, Danese S, Wiedenmann B, Dignass AU, Hammerle M and Sturm A (2007) Proteomic analysis of the inflamed intestinal mucosa reveals distinctive immune response profiles in Crohn’s disease and ulcerative colitis.
Journal of Immunology 179 295-304
Berndt U, Philipsen L, Bartsch S, Wiedenmann B, Baumgart DC, Hammerle M and Sturm A (2008) Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer. Cancer Research 68 880-888
Berneburg M, Plettenberg H and Krutmann J (2000) Photoaging of human skin.[In Process Citation]. Photodermatol Photoimmunol Photomed 16 239-244
Berneman ZN (2001) HTLV Molecular Biology and Pathogenesis: Airline Center, Warrenton, VA, USA. 17-19 March 2000. Leukemia 15 647-654
Bernier M, Kwon YK, Pandey SK, Zhu TN, Zhao RJ, Maciuk A, He HJ, Decabo R and Kole S (2005) Binding of manumycin A inhibits IkB kinase beta activity. Journal of Biologlical Chemistry 281 2551-2561
Bernotti S, Seidman E, Sinnett D, Brunet S, Dionne S, Delvin E and Levy E (2003) Inflammatory reaction without endogenous antioxidant response in Caco-2 cells exposed to iron/ascorbate-mediated lipid peroxidation. American Journal of Physiology: Gastrointestinal Liver Physiology 285 G898-G906
Bernstein LR (2006) Does nucleolin bind the NF kB DNA binding motif? Hepatology43 376
Berris KK, Repp AL and Kleerekoper M (2007) Glucocorticoid-induced osteoporosis. Current Opinion in Endocrinology, Diabetes and Obesity 14 446-450
Berry DM, Clark CS and Meckling-Gill KA (2002) 1alpha,25-dihydroxyvitamin D3 stimulates phosphorylation of IkBa and synergizes with TPA to induce nuclear translocation of NFkB during monocytic differentiation of NB4 leukemia cells. Experimental Cell Research 272 176-184
Berry EB, Keelan JA, Helliwell RJ, Gilmour RS and Mitchell MD (2005) Nanomolar and micromolar effects of 15-deoxy-delta12,14-Prostaglandin J2 on amnion-derived WISH epithelial cells: differential roles of PPAR-gamma, -delta and NF-kB. Molecular Pharmacology 68 169-178
Bersani F, Taulli R, Accornero P, Morotti A, Miretti S, Crepaldi T and Ponzetto C (2008) Bortezomib-mediated proteasome inhibition as a potential strategy for the treatment of rhabdomyosarcoma. European Journal of Cancer in press
Bertelsen M (2006) Multiplex analysis of inflammatory signaling pathways using a high-content imaging system. Methods in Enzymol in Enzymology 414C 348-363
Berthelot JM, Glemarec J, Guillot P, Laborie Y and Maugars Y (2002) New pathogenic hypotheses for spondyloarthropathies. Joint Bone Spine 69 114-122
Berti R, Williams AJ, Moffett JR, Hale SL, Velarde LC, Elliott PJ, Yao C, Dave JR and Tortella FC (2002) Quantitative real-time RT-PCR analysis of inflammatory gene expression associated with ischemia-reperfusion brain injury. Journal of Cerebral Blood Flow and Metabolism 22 1068-1079
Berti R, Williams AJ, Velarde LC, Moffett JR, Elliott PJ, Adams J, Yao C, Dave JR and Tortella FC (2003) Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat. Neurotoxicity Research 5 505-514
Berti-Mattera LN,Kern TS, Siegel RE, Nemet I and Mitchell R (2008) Sulfasalazine blocks the development of tactile allodynia in experimentally diabetic rats. Diabetes in press
Bertin J, Nir W-J, Fischer CM, Tayber OV, Errada PR, Grant JR, Keilty JJ, Gosselin ML, Robison KE, Wong GHW, Glucksmann MA and DiStefano PS (1999) Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kB. Journal of Biological Chemistry 274 12955-12958
Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS and Alnemri ES (2001) CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane- associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kB. Journal of Biological Chemistry 276 11877-11882
Bertino P, Marconi A, Palumbo L, Bruni BM, Barbone D, Germano S, Dogan AU, Tassi GF, Porta C, Mutti L and Gaudino G (2007) Erionite and asbestos differently cause transformation of human mesothelial cells. International Journal of Cancerin press
Bertolani C, Sancho-Bru P, Failli P, Bataller R, Aleffi S, Defranco R, Mazzinghi B, Romagnani P, Milani S, Gines P, Colmenero J, Parola M, Gelmini S, Tarquini R, Laffi G, Pinzani M and Marra F (2006) Resistin as an intrahepatic cytokine: overexpression during chronic injury and induction of proinflammatory actions in hepatic stellate cells. American Journal of Pathology 169 2042-2053
Berton MT, Linehan LA, Wick KR and Dunnick WA (2004) NF-kB elements associated with the Stat6 site in the germline {gamma}1 immunoglobulin promoter are not necessary for the transcriptional response to CD40 ligand. International Immunology 16 1741-1749
Bertoni F and Zucca E (2006) Delving deeper into MALT lymphoma biology. Journal of Clinical Investigation 116 22-26
Bertoni F, Zucca E and Cavilla F (2004) Mantle cell lymphoma. Current Opinions in Hematology 11 411-418
Bertout J and Thomas-Tikhonenko A (2006) Infection & neoplastic growth 101: the required reading for microbial pathogens aspiring to cause cancer. Cancer Treatment and Research 130 167-197
Bertrand F, Atfi A, Cadoret A, L’Allemain G, Robin H, Lascols O, Capeau J and Cherqui G (1998) A role for nuclear factor kB in the antiapoptotic function. Journal of Biological Chemistry 273 2931-2938
Bertrand F, Desbois-Mouthon C, Cadoret A, Prunier C, Robin H, Capeau J, Atfi A and Cherqui G (1999) Insulin antiapoptotic signaling involves insulin activation of the nuclear factor kB-dependent survival genes encoding tumor necrosis factor receptor-associated factor 2 and manganese-superoxide dismutase. Journal of Biological Chemistry 274 30596-30602
Besnard-Guerin C, Belaidouni N, Lassot I, Segeral E, Jobart A, Marchal C and Benarous R (2004) HIV-1 Vpu sequesters bTrCP in the cytoplasm and provokes the accumulation of b-catenin and others SCF-bTrCP substrates. Journal of Biological Chemistry 279 788-795
Besse A, Campos AD, Webster WK and Darnay BG (2007) TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase. Biochemical and BiophysicalResearch Communications in press
Besse A, Lamothe B, Campos AD, Webster WK, Maddineni U, Lin SC, Wu H and Darnay BG (2007) TAK1-dependent signaling requires functional interaction with TAB2/TAB3. Journal of Biological Chemistry 282 3918-3928
Besta F, Massberg S, Brand K, Muller E, Page S, Gruner S, Lorenz M, Sadoul K, Kolanus W, Lengyel E and Gawaz M (2002) Role of beta(3)-endonexin in the regulation of NF-kB-dependent expression of urokinase-type plasminogen activator receptor. Journal of Cell Science 115 3879-3888
Besta F, Muller I, Lorenz M, Massberg S, Bultmann A, Cabeza N, Richter T, Kremmer E, Nothdurfter C, Brand K and Gawaz M (2004) Reduced beta(3)-endonexin levels are associated with enhanced urokinase-type plasminogen activator receptor expression in ApoE(-/-) mice. Thrombosis Research 114 283-292
Beswick EJ, Pinchuk IV, Minch K, Suarez G, Sierra JC, Yamaoka Y and Reyes VE (2006) The Helicobacter pylori urease B subunit binds to CD74 on gastric epithelial cells and induces NF-kB activation and interleukin-8 production.Infection and Immunity 74 1148-1155
Beswick RA, Zhang H, Marable D, Catravas JD, Hill WD and Webb RC (2001) Long-term antioxidant administration attenuates mineralocorticoid hypertension and renal inflammatory response. Hypertension 37 781-786
Bettelli E, Dastrange M and Oukka M (2005) Foxp3 interacts with nuclear factor of activated T cells and NF-kB to repress cytokine gene expression and effector functions of T helper cells. Proceedings of the National Academy of Sciences USA 102 5138-5143
Bettencourt R and Ip YT (2004) Learning the codes of fly immunity. Molecular Cell 13 1-2
Bettencourt R, Roch P, Stefanni S, Rosa D, Colaco A, Serrao Santos R (2007) Deep sea immunity: unveiling immune constituents from the hydrothermal vent mussel Bathymodiolus azoricus. Marine Environmental Research in press
Bettencourt R, Tanji T, Yagi Y and Ip YT (2004) Toll and Toll-9 in Drosophila innate immune response. Journal of Endotoxin Research 10 261-268
Betts JC and Nabel GJ (1996) Differential regulation of NF-kB2(p100) processing and control by amino-terminal sequences. Molecular and Cellular Biology 16 6363-6371
Betts JC, Cheshire JK, Akira S, Kishimoto T and Woo P (1993) The role of NF-kB and NF-IL-6 transactivating factors in the synergistic activation of human serum amyloid A gene expression by interleukin-1 and interleukin-6. Journal of Biological Chemistry 268 25624-25631
Beug H, Müller H, Grieser S, Doederlein G and Graf T (1981)Hematopoietic cells transformed in vitro by REV-T avian reticuloendotheliosis virus express characteristics of very immature lymphoid cells. Virology 115 295-309
Bevelander M, Mayette J, Whittaker LA, Paveglio SA, Jones CC, Robbins J, Hemenway D, Akira S, Uematsu S and Poynter ME (2007) Nitrogen dioxide promotes allergic sensitization to inhaled antigen. Journal of Immunology 179 3680-3688
Bex F and Gaynor RB (1998) Regulation of gene expression by HTLV-I Tax protein. Methods 16 83-94
Bex F, McDowall A, Burny A and Gaynor R (1997) The human T-cell leukemia virus type 1 transactivator protein Tax colocalizes in unique nuclear structures with NF-kB. Journal of Virology 71 3484-3497
Bex F, Murphy K, Wattiez R, Burny A and Gaynor RB (1999) Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activation. Journal of Virology 73 738-745
Beyaert R (editor)(2003) Nuclear Factor kB: Regulation and Role in Disease. Kluwer Academic Publishers, The Netherlands, 426 pages
Beynon V, Cotofana S, Brand S, Lohse P, Mair A, Wagner S, Mussack T, Oschsenkuhn T, Folwaczyn M, Folwaczny C, Glas J and Torok HP (2008) NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes. Inflammatory Bowel Disease in press
Bezdecny SA, Karmaus P, Roth RA and Ganey PE (2007) 2,2′,4,4′-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-kB.
Toxicology and Applied Pharmacology 221 285-294
Bezzerri, V, Borgatti M, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Rizzotti P, Gambari R and Cabrini G (2008) Transcription factor oligodeoxynucleotides to NF-kB inhibit transcription of IL-8 in bronchial cells. American Journal of Respiratory Cell and Molecular Biology in press
Bezzi M, Hasmim M, Bieler G, Dormond O and Ruegg C (2003) Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: Evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt. Journal of Biological Chemistry 278 43603-43614
Bhagat L, Singh VP, Dawra RK and Saluja AK (2007) Sodium arsenite induces heat shock protein 70 expression and protects against secretagogue-induced trypsinogen and NF-kB activation.
Journal of Cellular Physiology in press
Bhagat L, Zhu FG, Yu D, Tang J, Wang H, Kandimalla ER, Zhang R and Agrawal S (2003) CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents. Biochemical and Biophysical Research Communications 300 853-861
Bhakar AL, Roux PP, Lachance C, Kryl D, Zeindler C and Barker PA (1999) The p75 neurotrophin receptor (p75NTR) alters tumor necrosis factor-mediated NF-kB activity under physiological conditions, but direct p75NTR-mediated NF-kB activation requires cell stress. Journal of Biological Chemistry 274 21443-21449
Bhakar AL, Tannis LL, Zeindler C, Russo MP, Jobin C, Park DS, MacPherson S and Barker PA (2002) Constitutive nuclear factor-kB activity is required for central neuron survival. Journal of Neuroscience 22 8466-8475
Bhandarkar SS and Arbiser JL (2007) Curcumin as an inhibitor of angiogenesis.Advances in Experimental Medicine and Biology 595 185-195
Bhanot UK, Moller P and Hasel C (2006) Dichotomy of fates of pancreatic epithelia in chronic pancreatitis: apoptosis versus survival. Trends inMolecular Medicine 12 351-357
Bhardwaj RS, Eblenkamp M, Berndt T, Tietze L and Klosterhalfen B (2004) Role of HSP70i in regulation of biomaterial-induced activation of human monocytes-derived macrophages in culture. Journal of Material Science and Material Medicine 12 97-106
Bhardwaj A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S and Aggarwal BB (2006) Resveratrol inhibits proliferation, induces apoptosis and overcomes chemoresistance through downregulation of STAT3 and nuclear factor-kB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood in press
Bharti A and Aggarwal B (2002) Nuclear factor-kB and cancer: its role in prevention and therapy. Biochemical Pharmacology 64 883-888
Bharti AC and Aggarwal BB (2004) Ranking the role of RANK ligand in apoptosis. Apoptosis 9 677-690
Bharti AC, Donato N, Singh S and Aggarwal BB (2003) Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kB and IkBa kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 101 1053-1062
Bharti AC, Shishodia S, Reuben JM, Weber D, Alexanian R, Raj-Vadhan S, Estrov Z, Talpaz M and Aggarwal BB (2003) Nuclear factor-kB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and their suppression leads to apoptosis. Blood 103 3175-3184
Bharti AC, Takada Y and Aggarwal BB (2004) Curcumin (diferuloylmethane) inhibits receptor activator of NF-kB ligand-induced NF-kB activation in osteoclast precursors and suppresses osteoclastogenesis. Journal of Immunology 172 5940-5947
Bharti AC, Takada Y, Shishodia S and Aggarwal BB (2004) Evidence that RANK ligand can suppress cell proliferation and induce apoptosis through activation of a nuclear factor-kB-independent and TRAF6-dependent mechanism. Journal of Biological Chemistry 279 6065-6076
Bhaskar V, Smith M and Courey AJ (2002) Conjugation of Smt3 to dorsal may potentiate the Drosophila immune response. Molecular and Cellular Biolgy 22 492-504
Bhaskar V, Valentine SA and Courey AJ (2000) A functional interaction between dorsal and components of the smt3 conjugation machinery. Journal of Biological Chemistry 275 4033-4040
Bhat GV and Temin HM (1990) Mutational analysis of v-rel, the oncogene of reticuloendotheliosis virus strain T. Oncogene 5 625-634
Bhat NR, Shen Q and Fan F (2003) TAK1-mediated induction of nitric oxide synthase gene expression in glial cells. Journal of Neurochemistry 87 238-247
Bhat-Nakshatri P, Campbell RA, Patel NM, Newton TR, King AJ, Marshall MS, Ali S and Nakshatri H (2004) Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function. British Journal of Cancer 90 853-859
Bhatia K, Huppi K, McKeithan T, Siwarski D, Mushinski JF and Magrath I(1991) Mouse bcl-3: cDNA structure, mapping and stage-dependent expression in B lymphocytes. Oncogene 6 1569-1573
Bhatia M, Brady M, Kang YK, Costello E, Newton DJ, Christmas SE, Neoptolemos JP and Slavin J (2002) MCP-1 but not CINC synthesis is increased in rat pancreatic acini in response to cerulein hyperstimulation. American Journal of Physiology: Gastrointestinal Liver Physiology 282 G77-G85
Bhatia N, Demmer TA and Spiegelman VS (2008) Inhibition of beta-TrCP function potentiates UVB-induced apoptosis in hTERT-immortalized normal human keratinocytes. Photochem Photobiol in press
Bhatnagar S and Schorey JS (2006) Elevated mitogen-activated protein kinase signalling and increased macrophage activation in cells infected with a glycopeptidolipid-deficient Mycobacterium avium. Cellular Microbiology 8 85-96
Bhat-Nakshatri P, Newton TR, Goulet Jr R, and Hakshatri H (1998) NF-kB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1a. Proceedings of the National Academy of Sciences USA 95 6971-6976
Bhat-Nakshatri P, Sweeney CJ and Nakshatri H (2002) Identification of signal transduction pathways involved in constitutive NF-kB activation in breast cancer cells. Oncogene 21 2066-2078
Bhatt BA, Dube JJ, Dedousis N, Reider JA and O’Doherty RM (2005) Diet-induced obesity and acute hyperlipidemia reduce IkBa levels in rat skeletal muscle in a fiber-type dependent manner. American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology 290 R233-240
Bhattacharjee RN, Park KS, Kumagai Y, Okada K, Yamamoto M, Uematsu S, Matsui K, Kumar H, Kawai T, Iida T, Hondo T, Takeuchi O and Akira S (2006) VP1686, a Vibrio type III secretion protein, induces Toll-like receptor independent apoptosis in macrophage through NF-kB inhibition. Journal of BiologicalChemistry 281 36897-36904
Bhattacharyya S, Borthakur A, Pant N, Dudeja PK and Tobacman JK (2007) Bcl10 mediates lipopolysaccharide (LPS)-induced activation of NFkB and IL-8 in human intestinal epithelial cells. American Journal of Physiology: Gastrointestinal and Liver Physiology in press
Bhattacharjya S, Domadia PN, Bhunia A, Malladi S and David SA (2007) High-resolution solution structure of a designed peptide bound to lipopolysaccharide: transferred nuclear overhauser effects, micelle selectivity, and anti-endotoxic activity.
Biochemistry 46 5864-5874
Bhattacharya A, Chandrasekar B, Rahman MM, Banu J, Kang JX and Fernandes G (2006) Inhibition of inflammatory response in transgenic fat-1 mice on a calorie-restricted diet. Biochemical and Biophysical Research Communications 349 925-930
Bhattacharya A, Rahman M, Banu J, Lawrence RA, McGuff HS, Garrett IR, Fischbach M and Fernandes G (2005) Inhibition of osteoporosis in autoimmune disease prone MRL/Mpj-Faslpr mice by N-3 fatty acids. Journal of the American College of Nutrition 24 200-209
Bhattacharya A and Steward R (2002) The Drosophila homolog of NTF-2, the nuclear transport factor-2, is essential for immune response. EMBO Reports 3 378-383
Bhattacharya D, Lee DU and Sha WC (2002) Regulation of Ig class switch recombination by NF-kB: retroviral expression of RelB in activated B cells inhibits switching to IgG1, but not to IgE. International Immunology 14 983-991
Bhattacharya R, Osburg B, Fischer D and Bickel U (2007) Targeted delivery of complexes of biotin-PEG-polyethylenimine and NF-kB decoys to brain-derived endothelial cells in vitro.
Pharmaceutical Research in press
Bhattacharya S, Mandal D, Sen GS, Pal S, Banerjee S, Lahiry L, Finke JH, Tannenbaum CS, Dast T and Sa G (2007) Tumor-induced oxidative stress perturbs nuclear factor-kappaB activity-augmenting tumor necrosis factor-alpha-mediated T-cell death: protection by curcumin. Cancer Research 67 362-370
Bhattacharya S, Ray Rm and Johnson LR (2005) Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kB activation but not GSK3beta activity. Apoptosis 10 759-776
Bhattacharya S, Ray RM and Johnson LR (2006) Integrin beta3 mediated Src activation regulates apoptosis in IEC-6 cells via Akt and STAT3. BiochemicalJournal 397 437-447
Bhattacharyya S, Dudeja PK and Tobacman JK (2008) Carrageenan-induced NFkB activation depends on distinct pathways mediated by reactive oxygen species and Hsp27 or by Bcl10. Biochemica et Biophysica Acta in press
Bhattacharyya S, Gill R, Chem ML, Zhang F, Linhardt RJ, Dudeja PK and Tobacman JK (2008) Toll-like receptor 4 mediates induction of the Bcl10-NF-kB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells. Journal of Biological Chemistry 283 10550-10558
Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS and Tisch R (2004) Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and IkB kinase activity. Blood 104 1100-1109
Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J and Benz CC (2008) Expression of microRNA-146 suppresses NF-kB activity with reduction of metastatic potential in breast cancer cells. Oncogene in press
Bhavsar PK, Sukkar MB, Khorasani N, Lee KY and Chung KF (2008) Glucocorticoid suppression of CX3CL1 (fractalkine) by reduced gene promoter recruitment of NF-kB. FASEB Journal in press
Bhojani MS, Chen G, Ross BD, Beer DG and Rehemtulla A (2005) Nuclear localized phosphorylated FADD induces cell proliferation and is associated with aggressive lung cancer. Cell Cycle 4 1478-1481
Bhoopathi P, Chetty C, Kunigal S, Vanamala S, Rao JS and Lakka SS (2008) Blockade of tumor growth due to MMP-9 inhibition is mediated by sequential activation of beta 1 integrin, ERK and NFkB. Journal of Biological Chemistry 283 1545-1552
Bhuiyan MM, Li Y, Banerjee S, Ahmed F, Wang Z, Ali S and Sarkar FH (2006) Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Research 66 10064-10072
Bhullar IS, Li YS, Miao H, Zandi E, Kim M, Shyy JY and Chien S (1998) Fluid shear stress activation of IkB kinase is integrin-dependent. Journal of Biological Chemistry 273 30544-30549
Bhusan S, Tchatalbachev S, Klug J, Fijak M, Pineau C, Chakraborty T and Meinhardt A (2008) Uropathogenic Escherichia coli block MyD88-dependent and activate MyD88-independent signaling pathways in rat testicular cells. Journal of Immunology 180 5537-5547
Bi X, Liu J, Yao Y, Baudry M and Lynch G (2005) Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in npc1-/- mouse brain. American Journal of Pathology 167 1081-1092
Bi Y, Sun WP, Chen X, Li M, Liang H, Cai MY, Zhu YH, He XY, Xu F and Weng JP (2008) Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats. Acta Diabetologica in press
Biagioli MC, Kaul P, Singh I and Turner RB (1999) The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells. Free Radical Biology and Medicine 26 454-462
Bian D, Su S, Mahanivong C, Cheng RK, Han Q, Pan ZK, Sun P and Huang S (2004) Lysophosphatidic acid stimulates ovarian cancer cell migration via a Ras-MEK kinase 1 pathway. Cancer Research 6 4209-4217
Bian F, Zhang MC and Zhu Y (2008) Inhibitory effect of curcumin on corneal neovascularization in vitro and in vivo. Ophthalmologica 222 178-186
Bian X, McAllister-Lucas LM, Shao F, Schumacher KR, Feng Z, Porter AG, Castle VP and Opipari Jr AW (2001) NF-kB activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells. Journal of Biological Chemistry 276 48921-48929
Bian X, Opipari AW Jr, Ratanaproeksa AB, Boitano AE, Lucas PC and Castle VP (2002) Constitutively active NF-kB is required for the survival of S-type neuroblastoma. Journal of Biological Chemistry 277 42144-42150
Bian ZM, Elner SG and Elner VM (2007) Thrombin-induced VEGF expression in human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science48 2738-2746
Bian ZM, Elner SG and Elner VM (2007) Regulation of VEGF mRNA expression and protein secretion by TGF-beta2 in human retinal pigment epithelial cells.Experimental Eye Research 84 812-822
Bian ZM, Elner SG, Yoshida A and Elner VM (2003) Human RPE-monocyte co-culture induces chemokine gene expression through activation of MAPK and NIK cascade. Experimental Eye Research 76 573-583
Bian ZM, Elner SG, Yoshida A, Kunkel SL, Su J and Elner VM (2001) Activation of p38, ERK1/2 and NIK pathways is required for IL-1beta and TNF-alpha-induced chemokine expression in human retinal pigment epithelial cells. Experimental Eye Research 73 111-121
Bian ZM, Elner VM, Yoshida A, Kunkel SL and Elner SG (2001) Signaling pathways for glycated human serum albumin-induced IL-8 and MCP-1 secretion in human RPE cells. Investigative Ophthalmology and Visual Science 42 1660-1668
Bian ZM, Elner SG, Yoshida A and Elner VM (2004) Differential involvement of phosphoinositide 3-Kinase/Akt in human RPE MCP-1 and IL-8 expression. Investigative Ophthalmology and Visual Science 45 1887-1896
Bianchi A, Moulin D, Sebillaud S, Koufany M, Galteau MM, Netter P, Terlain B and Jouzeau JY (2005) Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)gamma agonists on membrane-associated prostaglandin E2 synthase-1 in IL-1beta-stimulated rat chondrocytes: evidence for PPARgamma-independent inhibition by 15-deoxy-Delta12,14prostaglandin J2. Arthritis Research & Therapy7 R1325-R1337
Bianchi G, Montecucco F, Bertolotto M, Dallegri F and Ottonello L (2007) Immune complexes induce monocyte survival through defined intracellular pathways.Annals of the New York Academy of Sciences 1095 209-219
Bianchi R, Adami C, Giambanco I and Donato R (2006) S100B binding to RAGE in microglia stimulates COX-2 expression. Journal of Leukocyte Biology in press
Bianchi R, Giambanco I and Donato R (2008) S100B/RAGE-dependent activation of microglia via NF-kB and AP-1 co-regulation of COX-2 expression by S100B, IL-1b and TNF-a. Neurobiology of Aging in press
Biberthaler P, Stegmaier J, Mayer V, Kirchhoff C, Neth P, Mussack T, Mutschler W and Jochum M (2004) Initial posttraumatic translocation of NF-kB and TNF-alpha mRNA expression in peripheral blood monocytes of trauma patients with multiple injuries: a pilot study. Shock 22 527-532
Bibeau-Poirier A, Gravel SP, Clement JF, Rolland S, Rodier G, Coulombe P, Hiscott J, Grandvaux N, Meloche S and Servant MJ (2006) Involvement of the IkB kinase (IKK)-related kinases Tank-binding kinase 1/IKKi and Cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation. Journal of Immunology 177 5059-5067
Bickley JF, Ciucci A, Evans P, Roberts SM, Ross N and Gabriella Santoro M (2004) Reactions of some cyclopentenones with selected cysteine derivatives and biological activities of the product thioethers. Bioorganic & Medicinal Chemistry 12 3221-3227
Bidere N, Snow AL, Sakai K, Zhaneg L and Lenardo MJ (2006) Caspase-8 regulation by direct interaction with TRAF6 in T cell receptor-induced NF-kB activation.Current Biology 16 1666-1671
Bieche I, Chavey C, Andrieu C, Busson M, Vacher S, le Corre L, Guinebretiere JM, Burlinchon S, Lidereau R and Lazennec G (2007) CXC chemokines located in the 4q21 region are up-regulated in breast cancer. Endocrine Related Cancer 14 1039-1052
Bieg S, Simonson W, Ellefsen K and Lernmark A (2000) RelB is an early marker of autoimmune islet inflammation in the biobreeding (BB) rat. Pancreas 20 47-54
Bieler G, Hasmim M, Monnier Y, Imaizumi N, Ameyar M, Bamat J, Ponsonnet L, Chouaib S, Grell M, Goodman SL, Lejeune F and Ruegg C (2007) Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-kB activation and endothelial cell survival. Oncogene in press
Bielinska A, Shivdasani RA, Zhang LQ and Nabel GJ (1990) Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science 250 997-1000
Bielory L, Kempuraj D and Theoharides T (2003) Topical immunopharmacology of ocular allergies. Current Opinion in Allergy and Clinical Immunology 2 435-445
Bieneman AP, Chichester KL, Chen YH and Schroeder JT (2005) Toll-like receptor 2 ligands activate human basophils for both IgE-dependent and IgE-independent secretion. Journal of Allergy and Clinical Immunology 115 295-301
Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M, Sayed AA, Andrassy M, Schiekofer S, Schneider JG, Schulz JB, Heuss D, Neundorfer B, Dierl S, Huber J, Tritschler H, Schmidt AM, Schwaninger M, Haering HU, Schleicher E, Kasper M, Stern DM, Arnold B and Nawroth PP (2004) Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily. Journal of Clinical Investigation 114 1741-1751
Bierhaus A, Humpert PM and Nawroth PP (2004) NF-kB as a molecular link between psychosocial stress and organ dysfunction. Pediatic Nephrology 19 1189-1191
Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Kloting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, Haring HU, Schleicher E and Nawroth PP (2001) Diabetes-associated sustained activation of the transcription factor nuclear factor-kB. Diabetes 50 2792-2808
Bierhaus A, Wolf J, Andrassy M, Rohleder N, Humpert PM, Petrov D, Ferstl R, Von Eynatten M, Wendt T, Rudofsky G, Joswig M, Morcos M, Schwaninger M, McEwen B, Kirschbaum C and Nawroth PP (2003) A mechanism converting psychosocial stress into mononuclear cell activation. Proceedings of the National Academy of Sciences USA 100 1920-1925
Biermer M, PUro R and Schneider RJ (2003) Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid integrity through activation of NF-kB. Journal of Virology 77 4033-4042
Biesalski HK (2007) Polyphenols and inflammation: basic interactions. Current Opinion in Clinical Nutrition and Metabloic Care 10 724-728
Bigdeli MR and Khoshbaten A (2008) In vivo preconditioning with normobaric hyperoxia induces ischemic tolerance partly by triggering tumor necrosis factor-alpha converting enzyme/tumor necrosis factor-alpha/nuclear factor-kB. Neuroscience in press
Bijli KM, Fazal F, Minhajuddin M and Rahman A (2008) Activation of Syk by PKC delta regulates thrombin-induced ICAM-1 expression in endothelial cells via tyrosine phosphorylation of RelA/p65. Journal of Biological Chemistry in press
Bijli KM, Minhajuddin M, Fazal F, O’Reilly MA, Platanias LC and Rahman A (2006) c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 292 L396-L404
Bilej M, Joskova R, Van den Bergh R, Prochazkova P, Silerova M, Ameloot P, De Baetselier P and Beschin A (2006) An invertebrate TNF functional analogue activates macrophages via lectin-saccharide interaction with ion channels.International Immunology 18 1663-1670
Biliran Jr H, Banerjee S, Thakur A, Sarkar FH, Bollig A, Ahmed F, Wu J SUn Y and Liao JD (2007) c-Myc-induced chemosensitization is mediated by suppression of cyclin D1 expression and nuclear factor-kB activity in pancreatic cancer cells.Clinical Cancer Research 13 2811-2821
Billack B, Heck DE, Mariano TM, Gardner CR, Sur R, Laskin DL and Laskin JD (2002) Induction of cyclooxygenase-2 by heat shock protein 60 in macrophages and endothelial cells. American Journal of Physiology: Cell Physiology 283 C1267-C1277
Billadeau DD (2007) Primers on molecular pathways. The glycogen synthase kinasse-3beta. Pancreatology 7 398-402
Billecocq A, Spiegel M, Vialat P, Kohl A, Weber F, Bouloy M and Haller O (2004) NSs Protein of Rift Valley Fever Virus blocks interferon production by inhibiting host gene transcription. Journal of Virology 78 9798-9806
Billich A (2007) Drug evaluation: apillimod, an oral IL-12/IL-23 inhibitor for the treatment of autoimmune diseases and common variable immunodeficiency. IDrugs 10 53-59
Billiet L, Furman C, Larigauderie G, Copin C, Brand K, Fruchart JC and Rouis M (2005) Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages. Journal of Biological Chemistry 280 40310-40318
Billottet C, Grandage VL, Gale RE, Quattropani A, Rommel C, Vanhaesebroeck B and Khwaja A (2006) A selective inhibitor of the p110delta isoform of PI 3-kinase inhibits AML cell proliferation and survival and increases the cytotoxic effects of VP16. Oncogene in press
Billips BK, Schaeiffer AJ and Klumpp DJ (2008) The molecular basis of uropathogenic Escherichia coli evasion of the innate immune response in the bladder. Infection and Immunity in press
Bilyeu JD, Panta GR, Cavin LG, Barrett CM, Turner EJ, Sweatman TW, Israel M, Lothstein L and Arsura M (2004) Circumvention of nuclear factor kB-induced chemoresistance by cytoplasmic-targeted anthracyclines. Molecular Pharmacology 65 1038-1047
Bin LH, Xu LG and Shu HB (2003) TIRP: a novel TIR domain-containing adapter protein involved in Toll/interleukin-1 receptor signaling. Journal of Biological Chemistry 278 24526-24532
Bindhu OS, Ramadas K, Sebastian P and Pillai MR (2006) High expression levels of nuclear factor kB and gelatinases in the tumorigenesis of oral squamous cell carcinoma. Head and Neck in press
Bing Z, Huang JH and Liao WSL (2000) NFkB interacts with serum amyliod A3 enhancer factor to synergistically activate mouse serum amyloid A3 gene transcription. Journal of Biological Chemistry 275 31616-331628
Bingle L, Tetley TD and Bingle CD (2001) Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-kB. Am J Respir Cell Mol Biol 25 84-91
Bini R, Olivero G, Trombetta A, Castagna E and Cotogni P (2008) Effects of dimethyl sulfoxide, pyrrolidine dithiocarbamate, and methylprednisolone on nuclear factor-kB and heat shock protein 70 in a rat model of hemorrhagic shock. Journal of Trauma 64 1048-1054
Binnicker MJ, Williams RD and Apicella MA (2004) Gonococcal porin IB activates NF-kB in human urethral epithelium and increases the expression of host antiapoptotic factors. Infection and Immunity 72 6408-6417
Binsky I, Haran M, Starlets D, Gore Y, Lantner F, Harpaz N, Leng L, Goldenberg DM, Shvidel L, Berrebi A, Bucala R and Shachar I (2007) IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival.
Proceedings of the National Academy of Sciences USA 104 13408-13413
Biondo PD, Brindley DN, Sawyer MB and Field CJ (2008) The potential for treatment with dietary long-chain polyunsaturated n-3 fatty acids during chemotherapy. Journal of Nutritional Biochemistry in press
Biragyn A, Coscia M, Nagashima K, Sanford M, Young HA and Olkhanud P (2008) Murine beta-defensin 2 promotes TLR-4/MyD88-mediated and NF-kB-dependent atypical death of APCs via activation of TNFR2. Journal of Leukocyte Biology in press
Birbach A, Bailey ST, Ghosh S and Schmid JA (2004) Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kB inducing kinase NIK. Journal of Cell Science 117 3615-3624
Birchler T, Seibl R, Buchner K, Loeliger S, Seger R, Hossle JP, Aguzzi A and Lauener RP (2002) Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein. European Journal of Immunology 31 3131-3137
Bird MA, Black D, Lange PA, Samson CM, Hayden M and Behrns KE (2003) NFkB inhibition decreases hepatocyte proliferation but does not alter apoptosis in obstructive jaundice. Journal of Surgical Research 114 110-117
Bird MA, Lange PA, Schrum LW, Grisham JW, Rippe RA and Behrns KE (2002) Cholestasis induces murine hepatocyte apoptosis and DNA synthesis with preservation of the immediate-early gene response. Surgery 131 556-563
Birkenkamp KU, Esselink MT, Kruijer W and Vellenga E (1999) Differential effects of interleukin-3 and interleukin-1 on the proliferation and interleukin-6 protein secretion of acute myeloid leukemic cells; the involvement of ERK, p38 and STAT5. European Cytokine Network 10 479-490
Birkenkamp KU, Geugien M, Schepers H, Westra J, Lemmink HH and Vellenga E (2003) Constitutive NF-kB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway. Leukemia 18 103-112
Birnie R, Bryce SD, Roome C, Dussupt V, Droop A, Lang SH, Berry PA, Hyde CF, Lewis JL, Stower MJ, Maitland NJ and Collins AT (2008) Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions. Genome Biology in press
Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S and Belvisi MG (2007) Novel role for the Liver X nuclear receptor in the suppression of lung inflammatory responses.Journal of Biological Chemistry in press
Birrell MA, Hardaker E, Wong S, McCluskie K, Catley M, De Alba J, Newton R, Haj-Yahai S, Pun KT, Watts CJ, Shaw RJ, Savage TJ and Belvisi MG (2005) IkB kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma. American Journal of Respiratory Critical Care Medicine 172 962-971
Birrell MA, McCluskie K, Wong S, Donnelly LE, Barnes PJ and Belvisi MG (2005) Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kB-independent mechanism. FASEB Journal 19 840-841
Birrell MA, Wong S, Catley MC and Belvisi MG (2007) Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.Journal of Cellular Physiology in press
Birrell MA, Wong S, Hele DJ, McCluskie K, Hardaker E and Belvisi MG (2005) Steroid resistant inflammation in a rat model of COPD is associated with a lack of NF-kB activation. American Journal of Respiratory Critical Care Medicine 172 74-84
Birrell MA, Wong S, Hardaker E, McCluskie K, Collins M, Haj-Yahia S and Belvisi MG (2006) Ik-B kinase-2 independent inflammation in an airway disease model: relevance to the clinic. Molecular Pharmacology 69 1791-1800
Birrell MA, Wong S, McCluskie K, Catley MC, Hardarker EL, Haj-Yahia S and Belvisi MG (2006) Second generation inhibitors demonstrate the involvement of p38 MAP kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways. Journal of Pharmacology and ExperimentalTherapeutics 316 1318-1327
Bischof A, Hara T, Lin CH, Beyers AD and Hunig T (2000) Autonomous induction of proliferation, JNK and NF-kB activation in primary resting T cells by mobilized CD28. European Journal of Immunology 30 876-882
Bischoff DS, Zhu JH, Makhijani NS and Yamaguchi DT (2008) Acidic pH stimulates the production of the angiogenic CXC chemokine, CXCL8 (interleukin-8), in human adult mesenchymal stem cells via the extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and NF-kB pathways. Journal of Cellular Biochemistry in press
Bishnoi M, Chopra K and Kulkarni SK (2008) Activation of striatal inflammatory mediators and caspase-3 is central to haloperidol-induced orofacial dyskinesia. European Journal of Pharmacology in press
Bishnoi M, Chopra K and Kulkarni SK (2008) Differential striatal levels of TNF-a, NFkB p65 subunit and dopamine with chronic typical and atypical neuroleptic treatment: Role in orofacial dyskinesia. Progress in Neuropsychopharmacology, Biology and Psychiatry in press
Biswas A, Banerjee P, Mukherjee G and Biswas T (2007) Porin of Shigella dysenteriae activates mouse peritoneal macrophage through Toll-like receptors 2 and 6 to induce polarized type I response. Molecular Immunology 44 812-820
Biswas DK, Ahlers CM, Dezube BJ and Pardee AB (1993) Cooperative inhibition of NF-kB and Tat-induced superactivation of human immunodeficiency virus type 1 long terminal repeat. Proceedings of the National Academy of Sciences USA 90 11044-11048
Biswas DK, Cruz AP, Gansberger E and Pardee AB (2000) Epidermal growth factor-induced nuclear factor kB activation: a major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells. Proceedings of the National Academy of Sciences USA 97 8542-8547
Biswas DK, Dai SC, Cruz A, Weiser B, Graner E and Pardee AB (2001) The nuclear factor kappaB (NF-kB): a potential therapeutic target for estrogen receptor negative breast cancers. Proceedings of the National Academy of Sciences USA 98 10386-10391
Biswas DK, Dezube BJ, Ahlers CM and Pardee AB (1993) Pentoxifylline inhibits HIV-1 LTR-driven gene expression by blocking NF-kB action. Journal of Acquired Immune Deficiency Syndromes 6 778-786
Biswas DK and Igelhart JD (2006) Linkage between EGFR family receptors and nuclear factor kB (NF-kB) signaling in breast cancer. Journal of Cellular Physiology 209 645-652
Biswas DK, Martin KJ, McAlister C, Cruz AP, Graner E, Dai SC and Pardee AB (2003) Apoptosis caused by chemotherapeutic inhibition of nuclear factor-kB activation. Cancer Research 63 290-295
Biswas DK, Mhashilkar AM, Wwaniuk DS, Pezza JA, Oh LM, Kannangara GS, Tius MA and Pardee AB (1998) Inhibition of HIV-1 replication by combination of a novel inhibitor of TNF-a with AZT. Journal of Acquired Immune Deficiency Syndrome and Human Retroviruses 18 426-434
Biswas DK, Shi Q, Baily S, Strickland I, Ghosh S, Pardee AB and Iglehart JD (2004) NF-kB activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proceedings of the National Academy of Sciences USA 101 10137-10142
Biswas DK, Singh S, Shi Q, Pardee AB and Iglemart JD (2005) Crossroads of estrogen recetpor and NF-kB signaling. Science STKE DOI: 10.1126/stke.2882005pe27
Biswas G, Anandatheerthavarada HK, Zaidi M and Avadhani NG (2003) Mitochondria to nucleus stress signaling: a distinctive mechanism of NFkB/Rel activation through calcineurin-mediated inactivation of IkBb. Journal of Cell Biology 161 507-519
Biswas G, Srinivasan S, Anandatheerthavarada HK and Avadhani NG (2008) Dioxin-mediated tumor progression through activation of mitochondria-to-nucleus stress signaling. Proceedings of the National Academy of Sciences USA in press
Biswas G, Tang W, Sondheimer N, Guha M, Bansal S and Avadhani NG (2008) A distinctive physiological role for IkBb in the propagation of mitochondrial respiratory stress signaling. Journal of Biological Chemistry 283 12586-12594
Biswas P, Mantelli B, Delfanti F, Cota M, Vallanti G, de Filippi C, Mengozzi M, Vicenzi E, Lazzarin A and Poli G (2001) Tumor necrosis factor-alpha drives HIV-1 replication in U937 cell clones and upregulates CXCR4. Cytokine 13 55-59
Biswas P, Mantelli B, Delfanti F, Ferrarini M, Poli G and Lazzarin A (2003) CD30 ligation differentially affects CXCR4-dependent HIV-1 replication and soluble CD30 secretion in non-Hodgkin cell lines and in gamma delta T lymphocytes. European Journal of Immunology 33 3136-3145
Biswas S and Rahman I (2008) Modulation of steroid activity in chronic inflammation: a novel anti-inflammatory role for curcumin. Molecular Nutrition and Food Research in press
Biswas SK, Bist P, Chillon MK, Kajiji T, Del Fresno C, Yamamoto M, Lopez-Collazo E, Akira S and Tergaonkar V (2007) Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance. Journal of Immunology 179 4083-4092
Biswas SK and De Faria JB (2007) Which comes first: Renal inflammation or oxidative stress in spontaneously hypertensive rats? Free Radical Research 41 216-224
Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Bronte V, Pasqualini F, Vago L, Nebuloni M, Mantovani A and Sica A (2006) A distinct and unique transcriptional programme expressed by tumor-associated macrophages: defective NF-kB and enhanced IRF-3/STAT1 activation. Blood 107 2112-2122
Biswas SK, McClure D, Jimenez LA, Megson IL and Rahman I (2005) Curcumin induces glutathione biosynthesis and inhibits NF-kB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxidant and Redox Signaling 7 32-41
Bitko V, Garmon NE, Cao T, Estrada B, Oakes JE, Lausch RN and Barik S (2004) Activation of cytokines and NF-kB in corneal epithelial cells infected by respiratory syncytial virus: potential relevance in ocular inflammation and respiratory infection. BMC Microbiology 4 28
Bitko V, Shulyayeva O, Mazumder B, Musiyenko A, Ramaswamy M, Look DC and Barik S (2006) The nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by a NF-kB-dependent, interferon-independent mechanism and facilitate virus growth. Journal of Virology in press
Bitko V, Velazquez A, Yang L, Yang Y-C and Barik S (1997) Transcriptional induction of multiple cytokines by human respiratory syncytial virus requires activation of NF-kB and is inhibited by sodium salicylate and aspirin. Virology 232 369-378
Bittorf T, Buchse T, Sasse T, Jaster R and Brock J (2001) Activation of the transcription factor NF-kB by the erythropoietin receptor: structural requirements and biological significance. Cell Signaling 13 673-681
Bitzer M, von Gersdorff G, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M and Bottinger EP (2000) A mechanism of suppression of TGF-beta/SMAD signaling by NF-kB/RelA. Genes & Development 14 187-197
Bjersing JL, Eriksson K, Tarkowski A and Collins LV (2004) The arthritogenic and immunostimulatory properties of phosphorothioate oligodeoxynucleotides rely on synergy between the activities of the nuclease-resistant backbone and CpG motifs. Inflammation 28 39-51
Black D, Bird MA, Hayden M, Schrum LW, Lange P, Samson C, Hatano E, Rippe RA, Brenner DA and Behrns KE (2004) TNFa-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein. Surgery 135 619-628
Black PH (2006) The inflammatory consequences of psychologic stress: Relationship to insulin resistance, obesity, atherosclerosis and diabetes mellitus, type II. Medical Hypotheses 67 879-891
Blackwell NM, Sembi P, Newson JS, Lawrence T, Gilroy DW and Kabouridis PS (2004) Reduced infiltration and increased apoptosis of leukocytes at sites of inflammation by systemic administration of a membrane-permeable IkBa repressor. Arthritis & Rheumatism 50 2675-2684
Blackwell TS, Debelak JP, Venkatakrishnan A, Schot DJ, Harley DH, Pinson CW, Williams P, Washington K, Christman JW and Chapman WC (1999) Acute lung injury after hepatic cryoablation: correlation with NF-kB activation and cytokine production. Surgery 126 518-526
Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A and Christman JW (1999) Chemotactic gradients predict neutrophilic alveolitis in endotoxin-treated rats. American Journal of Respiraotry Critical Care Medicine 159 1644-1652
Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A and Christman JW (1999) Differential NF-kB activation after intratracheal endotoxin. American Journal of Physiology 277 L823-L830
Blackwell TS, Stecenko AA and Christman JW (2001) Dysregulated NF-kB activation in cystic fibrosis: evidence for a primary inflammatory disorder. Am J Physiol Lung Cell Mol Physiol 281 L69-L70
Blackwell TS, Yull FE, Chen CL, Venkatakrishnan A, Blackwell TR, Hicks DJ, Lancaster LH, Christman JW and Kerr LD (1999) Use of genetically altered mice to investigate the role of nuclear factor-kB activation and cytokine gene expression in sepsis-induced ARDS. Chest 116 73S-74S
Bladh LG, Liden J, Dahlman-Wright K, Reimers M, Nilsson S and Okret S (2005) Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between NF-kB and AP-1 repression. Molecular Pharmacology 67 815-826
Bladh LG, Liden J, Pazirandeh A, Rafter I, Dahlman-Wright K, Nilsson S and Okret S (2005) Identification of target genes involved in the anti-proliferative effect of glucocorticoids reveals a role for nuclear factor-kB repression. Molecular Endocrinology 19 632-643
Blaecke A, Delneste Y, Herbault N, Jeannin P, Bonnefoy JY, Beck and Aubry JP (2002) Measurement of nuclear factor-kB translocation on lipopolysaccharide-activated human dendritic cells by confocal microscopy and flow cytometry. Cytometry 48 71-79
Blair HC, Robinson LJ and Zaidi M (2005) Osteoclast signalling pathways. Biochemical and Biophysical Research Communications 328 728-738
Blair LA, Heitmeier MR, Scarim AL, Maggi LB, Jr. and Corbett JA (2001) Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kB activation by islets. Diabetes 50 283-290
Blair WS, Bogerd HP, Madore SJ and Cullen BR (1994) Mutational analysis of the transcription activation domain of RelA: identification of a highly synergistic minimal acidic activation module. Molecular and Cellular Biology 14 7226-7234
Blais M, Desilets A nad Asselin C (2005) Synergy between deacetylase inhibitors and IL-1b in activation of the serum amyloid A2 gene promoter. DNA Cell Biology 24 209-217
Blais V and Rivest S (2001) Inhibitory action of nitric oxide on circulating tumor necrosis factor- induced NF-kB activity and COX-2 transcription in the endothelium of the brain capillaries. Journal of Neuropathology and Experimental Neurology 60 893-905
Blais V, Zhang J and Rivest S (2002) In altering the release of glucocorticoids, ketorolac exacerbates the effects of systemic immune stimuli on expression of proinflammatory genes in the brain. Endocrinology 143 4820-4827
Blake SM, Eliopoulos AG, Dawson CW and Young LS (2001) The transmembrane domains of the EBV-encoded latent membrane protein 1 (LMP1) variant CAO regulate enhanced signalling activity. Virology 282 278-287
Blanchard F and Chipoy C (2005) Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases? Drug Discovery Today 10 197-204
Blanchard 2nd JA, Barve S, Joshi-Barve S, Talwalker R and Gates LK Jr (2001) Antioxidants inhibit cytokine production and suppress NF-kB activation in CAPAN-1 and CAPAN-2 cell lines. Dig Dis Sci 46 2768-2672
Blanchetot C and Boonstra J (2008) The ROS-NOX connection in cancer and angiogenesis. Critical Reviews of Eukaryotic Gene Expression 18 35-45
Blanchette J, Pouliot P and Olivier M (2007) Role of protein tyrosine phosphatases in the regulation of interferon-gamma-induced macrophage nitric oxide generation: implication of ERK pathway and AP-1 activation. Journal ofLeukocyte Biology 81 835-844
Blanco A, Alvarez S, Fresno M and Munoz-Fernandez MA (2008) Extracellular HIV-Tat induces cyclooxygenase-2 in glial cells through activation of nuclear factor of activated T cells. Journal of Immunology 180 530-540
Blanco AM and Guerri C (2007) Ethanol intake enhances inflammatory mediators in brain: role of glial cells and TLR4/IL-1RI receptors. Frontiers in Bioscience 12 2616-2630
Blanco AM, Pascual M, Valles SL and Guerri C (2004) Ethanol-induced iNOS and COX-2 expression in cultured astrocytes via NF-kB. Neuroreport 15 681-685
Blanco AM, Valles SL, Pascual M and Guerri C (2005) Involvement of TLR4/Type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. Journal of Immunology 175 6893-6899
Blanco B, Perez-Simon JA, Sanchez-Abarca LI, Carvajal-Vergara X, Mateos-Mazon J, Vidriales B, Lopez-Holgado N, Alberca M, Villaron E, Schenkein D, Maiso P, Pandiella A and San Miguel JF (2006) Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines. Blood 107 3575-3583
Blanco GA and Cooper EL (2004) Immune systems, geographic information systems (GIS), environment and health impacts. J Toxicol Environ Health B Crit Rev 7 465-480
Blancou P, Chenciner N, Fang RH, Monceaux V, Cumont MC, Guetard D, Hurtrel B and Wain-Hobson S (2004) Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus. Journal of Virology 78 1080-1092
Blanco-Colio LM, Munoz-Garcia B, Martin-Venturaa JL, Alvarez-Sala LA, Castilla M, Bustamante A, Lamuela-Raventos RM, Gomez-Gerique J, Fernandez-Cruz A, Millan J and Egido J (2006) Ethanol beverages containing polyphenols decrease nuclear factor kB activation in mononuclear cells and circulating MCP-1 concentrations in healthy volunteers during a fat-enriched diet. Atherosclerosis in press
Blanco-Colio LM, Valderrama M, Alvarez-Sala LA, Bustos C, Ortego M, Hernandez-Presa MA, Cancelas P, Gomez-Gerique J, Millan J and Egido J (2000) Red wine intake prevents nuclear factor-kB activation in peripheral blood mononuclear cells of healthy volunteers during postprandial lipemia. Circulation 102 1020-1026
Blank M, Krause I, Goldkorn T, Praprotnik S, Livneh A, Langevitz P, Kaganovsky E, Morgenstern S, Cohen S, Barak V, Eldor A, Weksler B and Shoenfeld Y (1999) Monoclonal anti-endothelial cell antibodies from a patient with Takayasu arteritis activate endothelial cells from large vessels. Arthritis and Rheumatism 42 1421-1432
Blank V, Kourilsky P and Israël A (1991) Cytoplasmic retention, DNA binding and processing of the NF-kB p50 precursor are controlled by a small region in its C-terminus. EMBO Journal 10 4159-4167
Blank V, Kourilsky P and Israël A (1992) NF-kB and related proteins: Rel/Dorsal homologies meet ankyrin-like repeats. Trends in Biochemical Sciences 17 135-140
Blasi E, Ardizzoni A, Colombari B, Neglia R, Baschieri C, Peppoloni S and Cinco M (2006) NF-kB activation and p38 phosphorylation in microglial cells infected with Leptospira or exposed to partially purified leptospiral lipoproteins.Microbial Pathogensis in press
Blau H, Klein K, Shalit I, Halperin D and Fabian I (2006) Moxifloxacin but not ciprofloxacin or azithromycin selectively inhibits IL-8, IL-6, ERK 1/2, JNK and NF-kB activation in a cystic fibrosis epithelial cell line. American Journal ofPhysiology: Lung Cell and Molecular Physiology in press
Blazek D and Peterlin BM (2008) Tat-SIRT1 tango. Molecular Cell 29 539-540
Blazka ME, Germolec DR, Simeonova P, Bruccoleri A, Pennypacker KR, Luster MI (1995) Acetaminophen-induced hepatotoxicity is associated with early changes in NF-kB and NF-IL6 DNA binding activity. Journal of Inflammation 47 138-150
Blazovics A, Hagymasi K and Pronai L (2004) Cytokines, prostaglandins, nutritive and non-nuitritive factors in inflammatory bowel diseases [Article in Hungarian]. Orv Hetil 145 2523-2529
Blazquez MV, Macho A, Ortiz C, Lucena C, Lopez-Cabrera M, Sanchez-Madrid F and Munoz E (1999) Extracellular HIV type 1 Tat protein induces CD69 expression through NF-kB activation: possible correlation with cell surface Tat-binding proteins. AIDS Research and Human Retroviruses 15 1209-1218
Blease K, Lewis A and Raymon HK (2003) Emerging treatments for asthma. Expert Opinion in Emerging Drugs 8 71-81
Blery M, Tze L, Miosge LA, Jun JE and Goodnow CC (2006) Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kB in B cell clonal anergy. Journal of Experimental Medicine 203 1773-1783
Blessing E, Preusch M, Kranzhofer R, Kinscherf R, Marx N, Rosenfeld ME, Isermann B, Weber CM, Kreuzer J, Grafe J, Katus HA and Bea F (2007) Anti-atherosclerotic properties of telmisartan in advanced atherosclerotic lesions in apolipoprotein E deficient mice. Atherosclerosis in press
Bloch-Damti A and Bashan N (2005) Proposed mechanisms for the induction of insulin resistance by oxidative stress. Antioxidants and Redox Signaling 7 1553-1567
Blondeau N, Widmann C, Lazdunski M and Heurteaux C (2001) Activation of the nuclear factor-kB is a key event in brain tolerance. Journal of Neuroscience 21 4668-4677
Blonska M, Shambharkar PB, Kobayashi M, Zhang D, Sakurai H, Su B and Lin X (2005) TAK1 is recruited to TNF-alpha receptor 1 in a rip-dependent manner and cooperates with MEKK3 leading to NF-kB activation. Journal of Biological Chemistry 280 43056-43063
Blonska M, You Y, Geleziunas R and Lin X (2004) Restoration of NF-kB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cells. Molecular and Cellular Biology 24 10757-10765
Bloomfield CD, Arthur DC, Frizzera G, Levine EG, Peterson BA and Gajl-Peczalska KJ (1983) Nonrandom chromosome abnormalities in lymphoma. Cancer Research 43 2975-2984
Bloor S, Ryzhakov G, Wagner S, Butler PJ, SMith DL, Krumbach R, Dikic I and Randow F (2008) Signal processing by its coil zipper domain activates IKKg. Proceedings of the National Academy of Sciences USA in press
Bloss T, Kaykas A and Sugden B (1999) Dissociation of patching by latent membrane protein-1 of Epstein-Barr virus from its stimulation of NF-kB activity. Journal of General Virology 80 3227-3232
Blum A (2003) Possible beneficial effects of soy protein on the vascular endothelium in postmenopausal women–future directions. Israel Medical Association Journal 5 56-58
Blum A, Setiawan T, Hang L, Stoyanoff K and Weinstock JV (2008) IL12 and IL23 induction of substance P synthesis in murine T cells and macrophages is subject to IL10 and TGFb regulation. Infection and Immunity in press
Blum D, Torch S, Nissou MF and Verna JM (2001) 6-hydroxydopamine-induced nuclear factor-kB activation in PC12 cells. Biochemical Pharmacology 62 473-481
Blum KA, Johjuson JL, Niedzwiecki D, Canellos GP, Cheson BD and Bartlett NL (2007) Single agent bortezomib in the treatment of relapsed and refractory Hodgkin lymphoma: Cancer and leukemia Group B protocol 50206. Leukemia and Lymphoma48 1313-1319
Blumberg RS, Pitman RS, Taylor CT and Colgan SP (2005) Cholera toxin potentiates influences of IFN-g through activation of NF-kB and release of tumor necrosis factor-a. Journal of Interferon and Cytokine Research 25 209-219
Blumenthal A, Ehlers S, Lauber J, Buer J, Lange C, Goldmann T, Heine H, Brandt E and Reiling N (2006) The Wingless homologue Wnt5a and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation. Blood 108 965-973
Bobrovnikova-Marjon EV, Marjon PL, Barbash O, Vander Jagt DL and Abcouwer SF (2004) Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of Nuclear Factor-kB and Activating Protein-1. Cancer Research 64 4858-4869
Boccia M, Freudenthal R, Blake M, de la Fuente V, Acosta G, Baratti C and Romano A (2007) Activation of hippocampal nuclear factor-kB by retrieval is required for memory reconsolidation. Journal of Neuroscience 27 13436-13445
Bochud PY, Hawn TR and Aderem A (2003) A toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. Journal of Immunology 170 3451-3454
Bockelmann R, Horn T, Gollnick H and Bonnekoh B (2005) Interferon-gamma-dependent in vitro model for the putative keratin 17 autoimmune loop in psoriasis: exploration of pharmaco- and gene-therapeutic effects. Skin Pharmacology and Physiology 18 42-54
Bocker U, Schottelius A, Watson JM, Holt L, Licato LL, Brenner DA, Sartor RB and Jobin C (2000) Cellular differentiation causes a selective down-regulation of interleukin (IL)-1beta-mediated NF-kB activation and IL-8 gene expression in intestinal epithelial cells. Journal of Biological Chemistry 275 12207-12213
Bocker W, Docheva D, Prall WC, Egea V, Pappou E, Robmann O, Popov C, Mutschler W, Ries C adn Schieker M (2008) IKK-2 is required for TNF-a-induced invasion and proliferation of human mesenchymal stem cells. Journal of Molecular Medicine in press
Bodak N, Hadj-Rabia S, Hamel-Teillac D, De Prost Y and Bodemer C (2003) Late recurrence of inflammatory first-stage lesions in incontinentia pigmenti: an unusual phenomenon and a fascinating pathologic mechanism. Archives of Dermatology 139 201-204
Boddupalli CS, Ghosh S, Showat Rahim S, Nair S, Ehtesham NZ, Hasnain SE and Mukhopadhyay S (2007) Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel. Free Radical Biology and Medicine42 686-697
Bode AM and Dong Z (2004) Targeting signal transduction pathways by chemopreventive agents. Mutation Research 555 33-51
Bode JG, Fischer R, Haussinger D, Graeve L, Heinrich PC and Schaper F (2001) The inhibitory effect of IL-1 beta on IL-6-induced alpha 2- macroglobulin expression is due to activation of NF-kB. Journal of Immunology 167 1469-1481
Boden G (2003) Effects of free fatty acids (FFA) on glucose metabolism: significance for insulin resistance and type 2 diabetes. Exp Clin Endocrinol Diabetes 111 121-124
Boden G and Carnell LH (2003) Nutritional effects of fat on carbohydrate metabolism. Best Pract Res Clin Endocrinol Metab 17 399-410
Boden G, She P, Mozzoli M, Cheung P, Gumireddy K, Reddy P, Xiang X, Luo Z and Ruderman N (2005) Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kB pathway in rat liver. Diabetes 54 3458-3465
Bodero AJ, Ye R and Lees-Miller SP (2003) UV-light induces p38 MAPK-dependent phosphorylation of Bcl10. Biochemical and Biophysical Research Communications 301 923-926
Bodine PV, Harris HA and Komm BS (1999) Suppression of ligand-dependent estrogen receptor activity by bone-resorbing cytokines in human osteoblasts. Endocrinology 140 2439-2451
Bodwell JE, Kingsley LA and Hamilton JW (2004) Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chemical Research in Toxicology 17 1064-1076
Body JJ, Greipp P, Coleman RE, Facon T, Geurs F, Fermand JP, Harousseau JL, Lipton A, Mariette X, Williams CD, Nakanishi A, Holloway D, Martin SW, Dunstan CR and Bekker PJ (2003) A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases. Cancer 97 887-892
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garrway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K and Hahn WC (2007) Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell129 1065-1079
Boehmelt G, Madruga J, Dörfler P, Briegel K, Schwarz H, Enrietto PJ and Zenke M (1995) Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER. Cell 80 341-352
Boehmelt G, Stengl G, Enrietto PJ and Zenke M (1995) v-rel protects transformed chicken bone marrow cells from apoptosis: a study with the conditional v-Rel estrogen receptor fusion oncoprotein v-RelER. Avian Immunology Research Group 1994, in press
Boehmelt G, Ulrich E, Kurzbauer, Mellitzer G, Bird A and Zenke M (1994) Structure and expression of the chicken retinoblastoma gene. Cell Growth & Differentiation 5 221-230
Boehmelt G, Walker A, Kabrun N, Mellitzer G, Beug H, Zenke M and Enrietto PJ (1992) Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression. EMBO Journal 11 4641-4652
Boehmer ED, Meehan MJ, Cutro B and Kovacs EJ (2005) Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathway. Mechanisms of Ageing and Development 126 1305-1313
Boehrer S, Nowak D, Hoelzer D, Mitrou PS and Chow KU (2006) The molecular biology of TRAIL-mediated signaling and its potential therapeutic exploitation in hematopoietic malignancies. Current Medicinal Chemistry 13 2091-2100
Boekhoudt GH, Guo Z, Beresford GW and Boss JM (2003) Communication between NF-kB and Sp1 controls histone acetylation within the proximal promoter of the monocyte chemoattractant protein 1 gene. Journal of Immunology 170 4139-4147
Boersmaa MC and Mefferet MK (2008) Novel roles for the NF-kB signaling pathway in regulating neuronal function. Science Signaling 1 pe7
Boesen EI, Sasser JM, Saleh MA, Potter WA, Woods M, Warner TD, Pollock JS and Pollock DM (2008) Interleukin-1{beta} but not interleukin-6 enhances renal and systemic endothelin production in vivo. American Journal of Physiology: Renal Physiology in press
Boffa DJ, Feng B, Sharma V, Dematteo R, Miller G, Suthanthiran M, Nunez R and Liou HC (2003) Selective loss of c-Rel compromises dendritic cell activation of T lymphocytes. Cellular Immunology 222 105-115
Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB and Sivler RM (2007) Down-regulation of collagen and connective tissue growth factor expression with hepatocyte growth factor in lung fibroblasts from white scleroderma patients via two signaling pathways.
Arthritis and Rheumatism 56 3468-3477
Bogazzi F, Raggi F, Ultimieri F, Russo D, Manariti A, D’Alessio A, Viacava P, Fanelli G, Gasperi M, Bartalena L and Martino E (2007) Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.Journal of Endocrinology 194 521-527
Bogunovic M, Dave SH, Tilstra JS, Chang DT, Harpaz ZN, Xiong H, Mayer LF and Plevy SE (2007) Enteroendocrine cells express functional Toll-like receptors.American Journal of Physiology: Gastrointestinal and Liver Physiology in press
Bohgaki M, Atsumi T, Yamashita Y, Yasuda S, Sakai Y, Furusaki A, Bohgaki T, Amengual O, Amasaki Y and Koike T (2004) The p38 mitogen-activated protein kinase (MAPK) pathway mediates induction of the tissue factor gene in monocytes stimulated with human monoclonal anti-{beta}2Glycoprotein I antibodies. International Immunology 16 1633-1641
Bohgaki M, Tsukiyama T, Nakajima A, Maruyama S, Watanabe M, Koike T and Hatakeyama S (2007) Involvement of Ymer in suppression of NF-kB activation by regulated interaction with lysine-63-linked polyubiquitin chain. Biochimica et Biophysica Acta in press
Bohlender J, Franke S, Sommer M and Stein G (2005) Advanced glycation end products: a possible link to angiotensin in an animal model. Annals of the New York Academy of Sciences 1043 681-684
Bohm M, Schulte U, Kalden H and Luger TA (1999) Alpha-melanocyte-stimulating hormone modulates activation of NF-k B and AP-1 and secretion of interleukin-8 in human dermal fibroblasts. Annals of the New York Academy of Sciences 885 277-286
Bohn E, Muller S, Lauber J, Geffers R, Speer N, Spieth C, Krejci J, Manncke B, Buer J, Zell A and Autenrieth IB (2004) Gene expression patterns of epithelial cells modulated by pathogenicity factors of Yersinia enterocolitica. Cellular Microbiology 6 129-141
Bohnenkamp HR, Papazsis KT, Burchell JM and Taylor-Papdimitriou J (2007) Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type I responses. Cellular Immunology in press
Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR and Greene WC (1988) The same inducible nuclear protein(s) regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell 53 827-836
Bohren KM< Gabbay KHJ and Owerbach D (2007) Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co(2+)-charged talon resin.
Protein Expression and Purification in press
Bohrer H and Nawroth PP (1998) Nuclear factor kB–a new therapeutic approach? [editorial; comment]. Intensive Care Med 24 1129-1130
Bohuslav J, Chen LF, Kwon H, Mu Y and Greene WC (2004) p53 induces NF-kB activation by an IkB kinase-independent mechanism involving RSK1 phosphorylation of p65. Journal of Biological Chemistry 279 26115-26125
Bohuslav J, Kravchenko VV, Parry GCN, Erlich JH, Gerondakis S, Mackman N and Ulevitch RJ (1998) Regulation of an essential innate immune response by the p50 subunit of NF-kB. Journal of Clinical Investigation 102 1645-1652
Boileau C, Amiable N, Martel-Pelletier J, Fahmi H, Duval N and Pelletier JP (2007) Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study. Arthritis Research and Therapy 9 R121
Bioleau C, Martel-Pelletier J, Fahmi H, Mineau F, Boily M and Pelletier JP (2007) The peroxisome proliferator-activated receptor gamma agonist pioglitazone reduces the development of cartilage lesions in an experimental dog model of osteoarthritis: in vivo protective effects mediated through the inhibition of key signaling and catabolic pathways. Arthritis and Rheumatism 56 2288-2298
Boileau TW, Bray TM and Bomser JA (2003) Ultraviolet radiation modulates nuclear factor kB activation in human lens epithelial cells. Journal of Biochemical and Molecular Toxicology 17 108-113
Boise LH and Thompson CB (1996) Hierachical control of lymphocyte survival. Science 274 67-68
Boise LH, Minn AJ, Noel PJ, June CH, Accavitti MA, Lindsten T and Thompson CB (1995) CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 3 87-98
Boissy P, Andersen TL, Abdallah BM, Kassem M, Plesner T and Delaisse JM (2005) Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation. Cancer Research 65 9943-9952
Boissy P, Andersen TL, Lund T, Kupisiewicz K, Plesner T and Delaisse JM (2008) Pulse treatment with the proteasome inhibitor bortezomib inhibits osteoclast resorptive activity in clinically relevant conditions. Leukemia Research inpress
Boivin G, Coulombe Z and Rivest S (2002) Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain. European Journal of Neuroscience 16 29-43
Bokarewa M, Nagaev I, Dahlberg L, Smith U and Tarkowski A (2005) Resistin, an adipokine with potent proinflammatory properties. Journal of Immunology 174 5789-5795
Bol GF, Jurrmann N and Brigelius-Flohe R (2003) Recruitment of the interleukin-1 receptor (IL-1RI)-associated kinase IRAK to the IL-1RI is redox regulated. Biology & Chemistry 384 609-617
Bol GF, Tewes F and Brigelius-Flohe R (1999) Interleukin-1 signaling is dependent on free thiols. Biofactors 10 175-178
Boland MP (2001) DNA damage signalling and NF-kB: implications for survival and death in mammalian cells. Biochemical Society Transactions 29 674-678
Boland MP and O’Neill LA (1998) Ceramide activates NFkB by inducing the processing of p105. Journal of Biological Chemistry 273 15494-15500
Boland MP, Fitzgerald KA and O’Neill LA (2000) Topoisomerase II is required for mitoxantrone to signal nuclear factor kB activation in HL60 cells. Journal of Biological Chemistry 275 25231-25238
Bolatto C, Chifflet S, Megighian A and Cantera R (2003) Synaptic activity modifies the levels of Dorsal and Cactus at the neuromuscular junction of Drosophila. Journal of Neurobiology 54 525-536
Boldogh I, Fons MP and Albrecht T (1993) Increased levels of sequence-specific DNA-binding proteins in human cytomegalovirus-infected cells. Biochemical and Biophysical Research Communications 197 1505-1510
Boldrick JC, Alizadeh AA, Diehn M, Dudoit S, Liu CL, Belcher CE, Botstein D, Staudt LM, Brown PO and Relman DA (2002) Stereotyped and specific gene expression programs in human innate immune reponses to bacteria. Proceedings of the National Academy of Sciences USA 99 972-977
Boleti AP, Ventura CA< Justo GZ, Silva RA, de Sousa AC, Ferreira CV, Yano T and Macedo ML (2008) Pouterin, a novel potential cytotoxic lectin-like protein with apoptosis-inducing activity in tumorigenic mammalian cells. Toxicon in press
Bolick DT, Orr AW, Whetzel A, Srinivasan S, Hatley ME, Schwartz MA and Hedrick CC (2005) 12/15-Lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kB. Arteriosclerosis, Thrombosis and Vascular Biology 25 2401-2307
Bolick DT, Srinivasan S, Whetzel A, Fuller LC and Hedrick CC (2006) 12/15 Lipoxygenase mediates monocyte adhesion to aortic endothelium in apolipoprotein E-deficient mice through activation of RhoA and NF-kB. Arteriosclerosis,Thrombosis and Vascular Biology 26 1260-1266
Bolick DT, Whetzel AM, Skaflen M, Deem T, Lee J and Hedrick CC (2007) Absence of the G protein-coupled receptor G2A in mice promotes monocyte/endothelial interactions in aorta. Circulation Research in press
Boll B, Hansen H, Heuck F, Reiners K, Borchmann P, Rothe A, Engert A and Pogge von Strandmann E (2005) The fully human anti-CD30 antibody 5F11 activates NF-kB and sensitizes lymphoma cells to bortezomib-induced apoptosis. Blood 106 1839-1842
Boller YC, Brandes LM, Russell RL, Lin ZP, Patierno SR and Kennedy KA (2001) Prostaglandin A1 inhibits stress-induced NF-kB activation and reverses resistance to topoisomerase II inhibitors. Oncology Research 12 383-395
Bolotina NA, Gasparian AV, Dubovaja TK, Evteev VA, Kobliakov VA (2007) Benzo[a]pyrene-dependent activation of transcription factors NF-kB and AP-1 related to tumor promotion in hepatoma cell cultures. Biochemistry (Moscow) 72552-557
Bolshakova A, Petukhova O, Turoverova L, Tentler D, Babakov V, Magnusson KE and Pinaev G (2007) Extra-cellular matrix proteins induce re-distribution of alpha-actinin-1 and alpha-actinin-4 in A431 cells. Cell Biology International in press
Bolt G, Berg K and Blixenkrone-Moller M (2002) Measles virus-induced modulation of host-cell gene expression. Journal of General Virology 83 1157-1165
Boltz KA and Carney GE (2008) Loss of p24 function in Drosophila melanogaster causes a stress response and increased levels of NF-kB-regulated gene products. BMC Genomics 9 212
Bommel H, Haake M, Luft P, Horejs-Hoeck J, Hein H, Bartels J, Schauer C, Poschl U, Kracht M and Duschl A (2003) The diesel exhaust component pyrene induces expression of IL-8 but not of eotaxin. International Immunopharmacology 3 1371-1379
Bomsztyk K, Rooney JW, Iwasaki T, Rachie NA, Dower SK and Sibley CH (1991) Evidence that interleukin-1 and phorbol esters activate NF-kB by different pathways: role of protein kinase C. Cell Regulation 2 329-335
Bonacchi A, Petrai I, Defranco RM, Lazzeri E, Annunziato F, Efsen E, Cosmi L, Romagnani P, Milani S, Failli P, Batignani G, Liotta F, Laffi G, Pinzani M, Gentilini P and Marra F (2003) The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C. Gastroenterology 125 1060-1076
Bonafoux D, Bonar S, Christine L, Clare M, Donnelly A, Guzova J, Kishore N, Lennon P, Libby A, Mathialagan S, McGhee W, Rouw S, Sommers C, Tollefson M, Tripp C, Weier R, Wolfson S and Min Y (2005) Inhibition of IKK-2 by 2-[(aminocarbonyl)amino]-5-acetylenyl-3-thiophenecarboxamides. Bioorganic Medicinal Chemical Letters 15 2870-2875
Bonaiuto C, McDonald PP, Rossi F and Cassatella MA (1997) Activation of Nuclear Factor-kB by beta-amyloid peptides and interferon-gamma in murine microglia. Journal of Neuroimmunology 77 51-56
Bonavida B (2007) Rituximab-induced inhibition of antiapoptotic cell survival pathways: implications in chemo/immunoresistance, rituximab unresponsiveness, prognostic and novel therapeutic interventions. Oncogene 26 3629-3636
Bonavida B, Baritaki S, Huerta-Yepez S Vega MI, Chatterjee D and Yeung K (2008) Novel therapeutic applications of nitric oxide donors in cancer: roles in chemo- and immunosensitization to apoptosis and inhibition of metastases. Nitric Oxide in press
Bonavida B, Huerta-Yepez S, Goodglick L, Mizutani Y and Miki T (2005) Can we develop biomarkers that predict response of cancer patients to immunotherapy? Biomarkers 10 69-76
Bonavida B and Vega MI (2005) Rituximab-mediated chemosensitization of AIDS and non-AIDS non-Hodgkin’s Lymphoma. Drug Resistance Update 8 27-41
Bonaz B (2007) The cholinergic anti-inflammatory pathway and the gastrointestinal tract. Gastroenterology 133 1370-1373
Boncoeur E, Criq VS, Bonvin E, Roque T, Henrion-Caude A, Gruenert DC, Clement A, Jacquot J and Tabary O (2007) Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: Potential mechanism for excessive IL-8 expression.International Journal of Biochemistry and Cell Biology in press
Boncoeur E, Roque T, Bonvin E, Saint-Criq V, Henrion-Caude A, Bonora M, Clement A, Tabary O and Jacquot J (2008) Cystic fibrosis transmembrane conductance regulator controls lung proteasomal degradation and nuclear factor-kB activity in conditions of oxidative stress. American Journal of Pathology in press
Bond M, Baker AH and Newby AC (1999) Nuclear factor kB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts. Biochemical and Biophysical Research Communications 264 561-567
Bond M, Chase AJ, Baker AH and Newby AC (2001) Inhibition of transcription factor NF-kB reduces matrix metalloproteinase-1, -3 and -9 production by vascular smooth muscle cells. Cardiovascular Research 50 556-565
Bond M, Fabunmi RP, Baker AH and Newby AC (1998) Synergistic upregulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-kB. FEBS Letters 435 29-34
Bondeson J, Brennan F, Foxwell B and Feldmann M (2000) Effective adenoviral transfer of IkBa into human fibroblasts and chondrosarcoma cells reveals that the induction of matrix metalloproteinases and proinflammatory cytokines is nuclear factor-kB dependent. Journal of Rheumatology 27 2078-2089
Bondeson J, Browne KA, Brennan FM, Foxwell BM and Feldmann M (1999) Selective regulation of cytokine induction by adenoviral gene transfer of IkBa into human macrophages: lipopolysaccharide-induced, but not zymosan-induced, proinflammatory cytokines are inhibited, but IL-10 is nuclear factor-kB independent. Journal of Immunology 162 2939-2945
Bondeson J, Foxwell B, Brennan F and Feldmann M (1999) Defining therapeutic targets by using adenovirus: blocking NF-kB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proceedings of the National Academy of Sciences USA 96 5668-5673
Bondeson J, Lauder S, Wainwright S, Amos N, Evans A, Hughes C, Feldmann M and Caterson B (2007) Adenoviral gene transfer of the endogenous inhibitor IkBa into human osteoarthritis synovial fibroblasts demonstrates that several matrix metalloproteinases and aggrecanases are nuclear factor-kB-dependent. Journal ofRheumatology in press
Bondzio A, Blankenstein P and Risse S (2003) Effects of hydrogen peroxide on bovine leukemia virus expression. Biology and Chemistry 384 1063-1072
Bone H and Williams NA (2001) Antigen-receptor cross-linking and lipopolysaccharide trigger distinct phosphoinositide 3-kinase-dependent pathways to NF-k B activation in primary B cells. International Immunology 13 807-816
Bonen DK and Cho JH (2003) The genetics of inflammatory bowel disease. Gastroenterology 124 521-536
Bonetti B, Stegagno C, Cannella B, Rizzuto N, Moretto G and Raine CS (1999) Activation of NF-kB and c-jun transcription factors in multiple sclerosis lesions. Implications for oligodendrocyte pathology. American Journal of Pathology 155 1433-1438
Bonetti B, Valdo P, Stegagno C, Tanel R, Zanusso GL, Ramarli D, Fiorini E, Turazzi S, Carner M and Moretto G (2000) Tumor necrosis factor alpha and human Schwann cells: signalling and phenotype modulation without cell death. Journal of Neuropathology and Experimental Neurology 59 74-84
Bonfield TL, Thomassen MJ, Farver CF, Abraham S, Koloze MT, ZHang X, Mosser DM and Culver DA (2008) Peroxisome proliferator-activated receptor-g regulates the expression of alveolar macrophage macrophage colony-stimulating factor. Journal of Immunology 181 235-242
Bonfigli A, Colagarina S, Falone S, Di Giulio C, Di Ilio C and Amicarelli F (2006) High levels of antioxidant enzymatic defence assure good protection against hypoxic stress in spontaneously diabetic rats. International Journal ofBiochemistry and Cell Biology 38 2196-2208
Bonfil RD, Dong Z, Trindade Filho JC, Sabbota A, Osenkowski P, Nabha S, Yamamoto H, Chinni SR, Zhao H, Mobashery S, Vessella Rl, Fridman R and Cher ML (2007) Prostate cancer-associated membrane type 1-matrix metalloproteinase. A pivotal role in bone Response and intraosseous tumor growth. American Journal ofPathology 170 2100-2111
Bonham CA, Peng L, Liang X, Chen Z, Wang L, Ma L, Hackstein H, Robbins PD, Thomson AW, Fung JJ, Qian S and Lu L (2002) Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kB oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig. Journal of Immunology 169 3382-3391
Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC and Donath MY (2008) Increased IL-1{beta} mRNA expression in b-cells of individuals with type 2 diabetes and regulation of IL-1b in human islets by glucose and auto-stimulation. Journal of Clinical Endrocrinology and Metabolism in press
Bonif M, Meuwis MA, Close P, Benoit V, Heyninck K, Chapelle JP, Bours V, Merville MP, Piette J, Beyaert R and Chariot A (2005) TNFa and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKg and NF-kB activation. Biochemical Journal 394 593-603
Bonilla FA and Geha RS (2006) Update on primary immunodeficiency diseases.Journal of Allergy and Clinical Immunology 117 S435-S441
Bonizzi G, Bebien M, Otero DC, Johnson-Vroom KE, Cao Y, Vu D, Jegga AG, Aronow BJ, Ghosh G, Rickert RC and Karin M (2004) Activation of IKKa target genes depends on recognition of specific kB binding sites by RelB:p52 dimers. EMBO Journal 23 4202-4210
Bonizzi G and Karin M (2004) The two NF-kB activation pathways and their role in innate and adaptive immunity. Trends in Immunology 25 280-288
Bonizzi G, Piette J, Merville MP and Bours V (2000) Cell type-specific role for reactive oxygen species in Nuclear Factor-kB activation by interleukin-1. Biochemical Pharmacology 59 7-11
Bonizzi G, Piette J, Schoonbroodt S, Griemers R, havard L, Merville M-P and Bours V (1999) Reactive oxygen intermediate-dependent NF-kB activation by interleukin-1b requires 5-lipoxygenase or NADPH oxidase activity. Molecular and Cellular Biology 19 1950-1960
Bonnard M, Mirtsos C, Suzuki S, Graham K, Huang J, Ng M, Itie A, Wakeham A, Shahinian A, Henzel WJ, Elia AJ, Shillinglaw W, Mak TW, Cao Z and Yeh WC (2000) Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-kB-dependent gene transcription. EMBO Journal 19 4976-4985
Bonello S, Zahringer C, Belaiba RS, Djordjevic T, Hess J, Michiels C, Kietzmann T and Gorlach A (2007) Reactive oxygen species activate the HIF-1a promoter via a functional NFkB site. Arteriosclerosis, Thrombosis, and Vascular Biology 27 755-761
Bonneau KR, Ng S, Foster H, Choi KB, Berkhout B, Rabson A, Mackewicz CE and Levy JA (2007) Derivation of infectious HIV-1 molecular clones with LTR mutations: Sensitivity to the CD8(+) cell noncytotoxic anti-HIV response. Virology in press
Bonnet MC, Daurat C, Ottone C and Meurs EF (2006) The N-terminus of PKR is responsible for the activation of the NF-kB signaling pathway by interacting with the IKK complex. Cellular Signaling 18 1865-1875
Bonnet MC, Weil R, Dam E, Hovanessian AG and Meurs EF (2000) PKR stimulates NF-kB irrespective of its kinase function by interacting with the IkB kinase complex. Molecular and Cellular Biology 20 4532-4542
Bonte D, Francois C, Castelain S, Wychowski C, Dubuisson J, Meurs EF and Duverlie G (2004) Positive effect of the hepatitis C virus nonstructural 5A protein on viral multiplication. Archives of Virology 149 1353-1371
Bonuccelli G, Sotgia F, Capozza F, Gazzerro E, Minetti C and Lisanti MP (2007) Localized treatment with a novel FDA-approved proteasome inhibitor blocks the degradation of dystrophin and dystrophin-associated proteins in mdx mice. Cell Cycle 6 in press
Bonvallot V, Baeza-Squiban A, Baulig A, Brulant S, Boland S, Muzeau F, Barouki R and Marano F (2001) Organic compounds from diesel exhaust particles elicit a proinflammatory response in human airway epithelial cells and induce cytochrome p450 1A1 expression. American Journal of Respiratory Cell and Molecular Biology 25 515-521
Bonvin C, Guillon A, van Bemmelen MX, Gerwins P, Johnson GL, Widmann C (2002) Role of the amino-terminal domains of MEKKs in the activation of NF kB and MAPK pathways and in the regulation of cell proliferation and apoptosis. Cellular Signaling 14 123-131
Boodhoo A, Wong AM, Williamson D, Voon D, Lee S, Allcock RJ and Price P (2004) A promoter polymorphism in the central MHC gene, IKBL, influences the binding of transcription factors USF1 and E47 on disease-associated haplotypes. Gene Expression 12 1-11
Boodoo S, Spannhake EW, Powell JD and Horton MR (2006) Differential regulation of hyaluronan-induced IL-8 and IP-10 in airway epithelial cells. AmericanJournal of Physiology: Lung Cell and Molecular Physiology291 L479-L486
Boomker JM, The TH, de Leij LF and Harmsen MC (2006) The human cytomegalovirus-encoded receptor US28 increases the activity of the major immediate-early promoter/enhancer. Virus Research 118 196-200
Boone DL, Lee EG, Libby S, Gibson PJ, Chien M, Chan F, Madonia M, Burkett PR and Ma A (2002) Recent advances in understanding NF-kB regulation. Inflammatory Bowel Disease 8 201-212
Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, Hurley P, Chien M, Chai S, Hitotsumatsu O, McNally E, Pickart C and Ma A (2004) The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nature Immunoloogy 5 1052-1060 (Correction. Nature Immunology 2005, 6 114)
Boonkewwan C, Ao M, Toskulkao C and Rao MC (2008) Specific immunomodulatory and secretory activities of stevioside and steviol in intestinal cells. Journal of Agricultural Food Chemistry in press
Boonkaewwan C, Toskulkao C and Vongsakul M (2006) Anti-inflammatory and immunomodulatory activities of stevioside and its metabolite steviol on THP-1 cells. Journal of Agriculture and Food Chemistry 54 785-789
Boonyaratanakornkit JB, Cogoli A, Li CF, Schopper T, Pippia P, Galleri G, Meloni MA and Hughes-Fulford M (2005) Key gravity-sensitive signaling pathways drive T-cell activation. FASEB Journal 19 2020-2022
Boonyasrisawat W, Eberle D, Bacci S, Zhang YY, Nolan D, Gervino EV, Johnstone MT, Trischitta V, Shoelson SE and Doria A (2007) Tag polymorphisms at the A20 (TNFAIP3) locus are associated with lower gene expression and increased risk of coronary artery disease in Type 2 diabetes. Diabetes 56 499-505
Boothby M (2001) Specificity of sn50 for NF-kB? Nature Immunology 2 471-472
Boothby M, Mora AL, Sherer DC, Brockman JA and Ballard DW (1997) Perturbation of the T-lymphocyte lineage in transgenic mice expressing a constitutive repressor of NF-kB. Journal of Experimental Medicine 185 1897-1907
Borg S, Bjorkman J, Eriksson S, Syk A, Andersson DI, Schesser K, Rhen M, Pettersson S and French NS (1999) Novel Salmonella typhimurium properties in host–parasite interactions. Immunology Letters 68 247-249
Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C and Gambari R (2004) Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression. Current Drug Targets 5 735-744
Borgatti M, Romanelli A, Saviano M, Pedone C, Lampronti I, Breda L, Nastruzzi C, Bianchi N, Mischiati C and Gambari R (2003) Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum. Oncology Research 13 279-287
Borger P, Koeter GH, Timmerman JA, Vellenga E, Tomee JF and Kauffman HF (1999) Proteases from Aspergillus fumigatus induce interleukin (IL)-6 and IL-8 production in airway epithelial cell lines by transcriptional mechanisms. Journal of Infectious Diseases 180 1267-1274
Borghaei RC, Rawlings PL Jr, Javadi M and Woloshin J (2004) NF-kB binds to a polymorphic repressor element in the MMP-3 promoter. Biochemical and Biophysical Research Communications 316 182-188
Borgland SL, Bowen GP, Wong NCW, Libermann TA and Muruve DA (2000) Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kB. Journal of Virology 74 3941-3947
Bork PM, Bacher S, Schmitz ML, Kaspers U and Heinrich M (1999) Hypericin as a non-antioxidant inhibitor of NF-kB. Planta Med 65 297-300
Bork PM, Schmitz ML, Kunhunt M, Escher C, and Heinrich M (1997) Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcritpion factor NF-kB. FEBS Letters 402 85-90
Bork PM, Schmitz ML, Wiemann SC, Kist M and Heinrich M (1996) Nahua Indian medicinal plants (Mexico): inhibitory activity on NF-kB as an anti-inflammatory model and antibacterial effects. Phytomedicine 3 263-269
Borm ME, Bodegraven AA, Mulder CJ, Kraal G and Bouma G (2005) A NFKB1 promoter polymorphism is involved in susceptibility to ulcerative colitis. International Journal of Immunogenetics 32 401-405
Borner C, Kraus J, Bedini A, Schraven B and Hollt V (2008) T cell receptor/CD28-mediated activation of human T lymphocytes induces expression of functional micro-opioid receptors. Molecular Pharmacology in press
Borner C, Kraus J, Schroder H, Ammer H and Hollt V (2004) Transcriptional regulation of the human {micro}-opioid receptor gene by interleukin-6. Molecular Pharmacology 66 1719-1726
Borquez J, Loyoloa LA, Morales G, San-Martin A, Roldan R, Marquez N and Munoz E (2007) Azorellane diterpenoids from Laretia acaulis inhibit nuclear factor-kB activity.
Phytotherapy Research in press
Borras C, Gambini J, Gomez-Cabrera MC, Sastre J, Pallard FV, Mann GE and Vina J (2006) Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: involvement of estrogen receptors, ERK1/2, and NFkB. FASEB Journal in press
Borras T (2003) Gene expression in the trabecular meshwork and the influence of intraocular pressure. Progress in Retina and Eye Research 22 435-463
Borset M, Hjorth-Hansen H, Johnsen AC, Seidel C, Waage A, Espevik T and Sundan A (1999) Apoptosis, proliferation and NF-kB activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor. European Journal of Haematology 63 345-353
Borthakur A, Saksena S, Gill RK, ALrefai WA, Ramaswamy K and Dudeja PK (2007) Regulation of monocarboxylate transporter 1 (MCT1) promoter by butyrate in human intestinal epithelial cells: Involvement of NF-kB pathway. Journal of CellularBiochemistry in press
Bortul R, Tazzari PL, Cappellini A, Tabellini G, Billi AM, Bareggi R, Manzoli L, Cocco L and Martelli AM (2003) Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kB activation and cFLIP(L) up-regulation. Leukemia 17 379-389
Bosca L, Bodelon OG, Hortelano S, Casellas A, Bosch F (2000) Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta. Gene Therapy 7 817-825
Boscolo P, del Signore A, Sabbioni E, Di Gioacchino M, Di Giampaolo L, Reale M, Conti P, Paganelli R and Giaccio M (2003) Effects of resveratrol on lymphocyte proliferation and cytokine release. Ann Clin Lab Sci 33 226-231
Bose Jr HR (1992) The Rel family: models for transcriptional regulation and oncogenic transformation. Biochimica et Biophysica Acta 1114 1-17
Bose S and Banerjee AK (2003) Innate immune response against nonsegmented negative strand RNA viruses. Journal of Interferon and Cytokine Research 23 401-412
Bose S, Kar N, Maitra R, DiDonato JA and Banerjee AK (2003) Temporal activation of NF-kB regulates an interferon-independent innate antiviral response against cytoplasmic RNA viruses. Proceedings of the National Academy of Sciences USA 100 10890-10895
Bosisio C, Marazzi I, Agresti A, Shimizu N, Bianchi ME and Natoli G (2006) A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kB-dependent gene activity. EMBO Journal in press
Bosisio D, Polentarutti N, Sironi M, Bernasconi S, Miyake K, Webb GR, Martin MU, Mantovani A and Muzio M (2002) Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood 99 3427-3431
Bosnjak B, Katic M, Hrvacic B, Zupanovic Z and Poljak-Blazi M (2004) Effect of ferric sorbitol citrate (FSC) administration on NF-kB in macrophages and spleen cells of rats. Immunopharmacology and Immunotoxicology 26 43-52
Bossen C and Schneider P (2006) BAFF, APRIL and their receptors: Structure, function and signaling. Seminars in Immunology in press
Bossert B, Marozin S and Conzelmann KK (2003) Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3. Journal of Virology 77 8661-8668
Bossis G, Salinas S, Cartier C, Devaux C and Briant L (2002) NF-kB activation upon interaction of HIV-1 envelope glycoproteins with cell surface CD4 involves IkB kinases. FEBS Letters 516 257-264
Bossios A, Gourgiotis D, Skevaki CL, Saxoni-Papageorgiou P, Lotvall J, Psarras S, Karpathios T, Constandopoulos AG, Johnston SL and Papadopoulos NG (2008) Rhinovirus infection and house dust mite exposure synergize in inducing bronchial epithelial cell interleukin-8 release. Clincical and Experimental Allergy in press
Bostanci N, Emingil G, Afacan B, Han B, Ilgenli T, Atilla G, Hughes FJ and Belibasakis GN (2008) Tumor necrosis factor-alpha-converting enzyme (TACE) levels in periodontal diseases. Journal of Dental Research 87 273-277
Bostanci N, Ilgenli T, Emingil G, Afacan B, Han B, Toz H, Atilla G, Hughes FJ and Belibasakis GN (2007) Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio. Journal of ClinicalPeriodontology in press
Botchkarev VA and Fessing MY (2005) Edar signaling in the control of hair follicle development. Journal of Investigative Dermatology Symposium Proceedings10 247-251
Botchkina GI, Geimonen E, Bilof ML, Villarreal O and Tracey KJ (1999) Loss of NF-kB activity during cerebral ischemia and TNF cytotoxicity. Molecular Medicine 5 372-381
Botella LM, Puig-Kroger A, Almendro N, Sanchez-Elsner T, Munoz E, Corbi A and Bernabeu C (2000) Identification of a functional NF-kB site in the platelet endothelial cell adhesion molecule-1 promoter. Journal of Immunology 164 1372-1378
Bothwell M (1996) p75NTR: a receptor after all. Science 272 506-507
Bottero V, Busuttil V, Loubat A, Magne N, Fischel JL, Milano G and Peyron JF (2001) Activation of nuclear factor kB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells. Cancer Research 61 7785-7791
Bottero V, Imbert V, Frelin C, Formento JL and Peyron JF (2003) Monitoring NF-kB transactivation potential via real-time PCR quantification of IkB-a gene expression. Molecular Diagnosis 7 187-194
Bottero V, Rossi F, Samson M, Mari M, Hofman P, Peyron JF (2001) IkBa, the NF-kB inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator. Journal of Biological Chemistry 276 21317-21324
Bottero V, Withoff S and Verma IM (2006) NF-kB and the regulation of hematopoiesis. Cell Death and Differentiation in press
Bottex-Gauthier C, Pollet S, Favier A and Vidal DR (2002) The Rel/NF-kB transcription factors: complex role in cell regulation [Article in French]. Pathol Biol (Paris) 50 204-211
Bottino R, Balamurugan AN, Tse H, Thirunavukkarasu C, Ge X, Profozich J, Milton M, Ziegenfuss A, Trucco M and Piganelli JD (2004) Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes 53 2559-2568
Bouchard MJ, Wang L and Schneider RJ (2006) Activation of focal adhesion kinase by Hepatitis B virus HBx protein: multiple functions in viral replication.Journal of Virology 80 4406-4414
Bouchier-Hayes L and Martin SJ (2002) CARD games in apoptosis and immunity. EMBO Reports 3 616-621
Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh EM, MacFarlane M and Martin SJ (2001) CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kB activation pathways. Journal of Biological Chemistry 276 44069-44077
Bouchier-Hayes L and Martin SJ (2004) CARDINAL roles in apoptosis and NFkB activation. Vitamins and Hormones 67 133-147
Boukerche H, Su ZZ, Emdad L, Sarkar D and Fisher PB (2007) mda-9/syntenin regulates the metastatic phenotype in human melanoma cells by activating nuclear factor-kB. Cancer Research 67 1812-1822
Boulanger D, Bureau F, Melotte D, Mainil J and Lekeux P (2003) Increased nuclear factor kB activity in milk cells of mastitis-affected cows. Journal of Dairy Science 86 1259-1267
Boulares AH, Ferran MC and Lucas-Lenard J (1996) NF-kB activation is delayed in mouse L929 cells infected with interferon suppressing, but not inducing, vesicular somatatis virus strains. Virology 218 71-80
Boulares HA, Giardina C, Navarro CL, Khairallah EA and Cohen SD (1999) Modulation of serum growth factor signal transduction in Hepa 1-6 cells by acetaminophen: an inhibition of c-myc expression, NF-kB activation, and Raf-1 kinase activity. Toxicol Sci 48 264-274
Boulougouris G, McLeod JD, Patel YI, Ellwood CN, Walker LS and Sansom DM (1999) IL-2-independent activation and proliferation in human T cells induced by CD28. Journal of Immunology 163 1809-1816
Bouloumie A, Marumo T, Lafontan M and Busse R (1999) Leptin induces oxidative stress in human endothelial cells. FASEB Journal 13 1231-1238
Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J, Ghidelli S, Hopf C, Huhse B, Mangano R, Michon AM, Schirle M, Schlegl J, Schwab M, Stein MA, Bauer A, Casari G, Drewes G, Gavin AC, Jackson DB, Joberty G, Neubauer G, Rick J, Kuster B and Superti-Furga G (2004) A physical and functional map of the human TNF-alpha/NF-kB signal transduction pathway. Nature Cell Biology 6 97-105
Bounou S, Dumais N and Tremblay MJ (2001) Attachment of human immunodeficiency virus-1 (HIV-1) particles bearing host-encoded B7-2 proteins leads to nuclear factor-kB- and nuclear factor of activated T cells-dependent activation of HIV-1 long terminal repeat transcription. Journal of Biological Chemistry 276 6359-6369
Bour S, Perrin C, Akari H, Strebel K (2001) The human immunodeficiency virus type 1 Vpu protein inhibits NF-kB activation by interfering with bTrCP-mediated degradation of IkB. Journal of Biological Chemistry 276 15920-15928
Bourbia A, Cruz MA and Rozycki HJ (2005) NF-kB in tracheal lavage fluid from intubated premature infants: Association with inflammation, oxygen and outcome.Arch Dis Child Fetal Neonatal Ed in press
Bourcier T, Sukhova G and Libby P (1997) The nuclear factor kB singaling pathway participates in dysregulation of vascular smooth muscle cells in vitro and in human artherosclerosis. Journal of Biological Chemistry 20 15817-15824
Bourgarel-Rey V, Vallee S, Rimet O, Champion S, Braguer D, Desobry A, Briand C and Barra Y (2001) Involvement of nuclear factor kappaB in c-Myc induction by tubulin polymerization inhibitors. Molecular Pharmacology 59 1165-1170
Bourgier C, Haydont V, Milliat F, Francois A, Holler V, Lasser P, Bourhis J, Mathe D and Vozenin-Brotons MC (2005) Inhibition of Rho kinase modulates radiation induced fibrogenic phenotype in intestinal smooth muscle cells through alteration of the cytoskeleton and connective tissue growth factor expression. Gut 54 336-343
Bourhis LL, Benko S and Girardin SE (2007) Nod1 and Nod2 in innate immunity and human inflammatory disorders. Biochemical Society Transactions 35 1479-1484
Bourke E and Moynagh PN (1999) Antiinflammatory effects of glucocorticoids in brain cells, independent of NF-kB. Journal of Immunology 163 2113-2119
Bourke E, Kennedy EJ and Moynagh PN (2000) Loss of IkB-b is associated with prolonged NF-kB activity in human glial cells. Journal of Biological Chemistry 275 39996-40002
Bournazos S, Rennie J, Hart SP, Fox KA and Dransfield I (2008) Monocyte functional responsiveness after PSGL-1-mediated platelet adhesion is dependent on platelet activation status. Arteriosclerosis, Thrombosis, and Vascular Biology in press
Bourne KZ, Ferrari DC, Lange-Dohna C, Rossner S, Wood TG and Perez-Polo JR (2007) Differential regulation of BACE1 promoter activity by nuclear factor-kB in neurons and glia upon exposure to beta-amyloid peptides. Journal ofNeuroscience Research in press
Bours V (1999) NF-kB and cancers [Article in French]. Bull Mem Acad R Med Belg 154 335-345
Bours V, Azarenko V, Dejardin E and Sienbenlist U (1994) Human RelB (I-Rel) functions as a kB site-dependent transactivating member of the family of Rel-related proteins. Oncogene 9 1699-1702
Bours V, Bentires-Alj M, Hellin A-C, Viatour P, Robe P, Delhalle S, Benoit V and Merville M-P (2000) Nuclear factor-kB, Cancer and Apoptosis. Biochemical Pharmacology 60 1085-1090
Bours V, Bonizzi G, Bentires-Alj M, Bureau F, Piette J, Lekeux P and Merville M-P (2000) NF-kB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment. Toxicology 153 27-38
Bours V, Burd PR, Brown K, Villalobos J, Park S, Ryseck R-P, Bravo R, Kelly K and Siebenlist U (1992) A novel mitogen-inducible gene product related to p50/p105-NF-kB participates in transactivation through a kB site. Molecular and Cellular Biology 12 685-695
Bours V, Dejardin E, Goujon-Letawe F, Merville M-P and Castronovo V (1994) The NF-kB transcription factor and cancer: high expression of NF-kB- and IkB-related proteins in tumor cell lines. Biochemical Pharmacology 47 145-149
Bours V, Franzoso G, Azarenko V, Park, S, Kanno T, Brown K and Siebenlist U (1993) The oncoprotein Bcl-3 directly transactivates through kB motifs via association with DNA-binding p50B homodimers. Cell 72 729-739
Bours V, Franzoso G, Brown K, Park S, Azarenko V, Tomita-Yamaguchi M, Kelly K and Siebenlist U (1992) Lymphocyte activation and the family of NF-kB transcription complexes. Current Topics in Microbiology and Immunology 182 411-420
Bours V, Villalobos J, Burd PR, Kelly K and Siebenlist U (1990)Cloning of a mitogen-inducible gene encoding a kB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs. Nature 348 76-80
Bourteele S, Oesterle K, Pleschka S, Unterstab G, Ehrhardt C, Wolff T, Ludwig S and Planz O (2005 Constitutive activation of the transcription factor NF-kB results in impaired Borna Disease Virus replication. Journal of Virology 79 6043-6051
Bourteele S, Oesterle K, Weinzierl AO, Paxian S, Riemann M, Schmid RM and Planz O (2007) Alteration of NF-kB activity leads to mitochondrial apoptosis after infection with pathological prion protein. Cellular Microbiology in press
Bousserouel S, Brouillet A, Bereziat G, Raymondjean M and Andreani M (2003) Different effects of n-6 and n-3 polyunsaturated fatty acids on the activation of rat smooth muscle cells by interleukin-1beta. Journal of Lipid Research 44 610-611
Boutet P, Sulon J, Closset R, Detilleux J, Beckers JF, Bureau F and Lekeux P (2007) Prolactin-induced activation of nuclear factor kB in bovine mammary epithelial cells: role in chronic mastitis. Journal of Dairy Science 90 155-164
Bouzyk E, Gradzka I, Iwanenko T, Kruszewski M, Sochanowicz B and Szumiel I (2000) The response of L5178Y lymphoma sublines to oxidative stress: antioxidant defence, iron content and nuclear translocation of the p65 subunit of NF-kB. Acta Biochim Pol 47 881-888
Bowen EJ, Schmidt TW, Firm CS, Russo AF and Durham PL (2005) Tumor necrosis factor-a stimulation of calcitonin gene-related peptide expression and secretion from rat trigeminal ganglion neurons. Journal of Neurochemistry in press
Bowers WJ, Baglia LA and Ruddell A (1996) Regulation of avian leukosis virus long terminal repeat-enhanced transcription by C/EBP-Rel interactions. Journal of Virology 70 3051-3059
Bowie A and O’Neill LA (2000) Oxidative stress and nuclear factor-kB activation: a reassessment of the evidence in the light of recent discoveries. Biochemical Pharmacology 59 13-23
Bowie A and O’Neill LAJ (2000) Vitamin C inhibits NF-kB activation by TNF via the activation of p38 mitogen-activated protein kinase. Journal of Immunology 165 7180-7188
Bowie A, Kiss-Toth E, Symons JA, Smith GL, Dower SK and O’Neill LA (2000) A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll- like receptor signaling. Proceedings of the National Academy of Sciences USA 97 10162-10167
Bowie AG (2008) Insights from vaccinia virus into Toll-like receptor signalling proteins and their regulation by ubiquitin: role of IRAK-2. Biochemical Society Transactions 36 449-452
Bowie AG, Zhan J and Marshall WL (2004) Viral appropriation of apoptotic and NF-kB signaling pathways. J Cell Biochem 91 1099-1108
Bowler RP, Arcaroli J, Abraham E, Patel M, Chang LY, Crapo JD (2003) Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury. Am J Physiol Lung Cell Mol Physiol 284 L680-L687
Boya P, Larrea E, Sola I, Majano PL, Jimenez C, Civeira MP and Prieto J (2001) Nuclear factor-kB in the liver of patients with chronic hepatitis C: decreased RelA expression is associated with enhanced fibrosis progression. Hepatology 34 1041-1048
Boya P, Morales MC, Gonzalez-Polo RA, Andreau K, Gourdier I, Perfettini JL, Larochette N, Deniaud A, Baran-Marszak F, Fagard R, Feuillard J, Asumendi A, Raphael M, Pau B, Brenner C and Kroemer G (2003) The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family. Oncogene 22 6220-6230
Boyault S, Bianchi A, Moulin D, Morin S, Francois M, Netter P, Terlain B and Bordji K (2004) 15-Deoxy-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkBa degradation in rat chondrocytes through a PPARg-independent pathway. FEBS Letters 572 33-40
Boyault S, Simonin MA, Bianchi A, Compe E, Liagre B, Mainard D, Becuwe P, Dauca M, Netter P, Terlain B and Bordji K (2001) 15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways. FEBS Letters 501 24-30
Boyce BF, Schwarz EM and Xing L (2006) Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease. Current Opinion in Rheumatology 18 427-432
Boyce BF and Xing L (2008) Functions of RANKL/RANK/OPG in bone modeling and remodeling. Archives of Biochemistry and Biophysics in press
Boyce BF, Xing L, Franzoso G and Siebenlist U (1999) Required and nonessential functions of nuclear factor-k B in bone cells. Bone 25 137-139
Boyce BF, Xing L, Shakespeare W, Wang Y, Dalgarno D, Iuliucci J and Sawyer T (2003) Regulation of bone remodeling and emerging breakthrough drugs for osteoporosis and osteolytic bone metastases. Kidney International 63 2-5
Boyce BF, Yamashita T, Yao Z, Zhang Q, Li F and Xing L (2005) Roles for NF-kB and c-Fos in osteoclasts. Journal of Bone and Mineral Metabolism 23 Suppl 11-15
Boyd JH, Divangahi M, Yahiaoui L, Gvozdic D, Qureshi S and Petrof BJ (2006) Toll-like receptors differentially regulate CC and CXC chemokines in skeletal muscle via NF-kB and calcineurin. Infection and Immunity in press
Boyd JH, Mathur S, Wang Y, Bateman RM and Walley KR (2006) Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kB dependent inflammatory response. Cardiovascular Research in press
Boye K, Grotterod I, Aasheim HC, Hovig E and Maelandsmo GM (2008) Activation of NF-kB by extracellular S100A4: Analysis of signal transduction mechanisms and identification of target genes. International Journal of Cancer in press
Boyer A, Chadda K, Salah A and Annane D (2006) Glucocorticoid treatment in patients with septic shock: effects on vasopressor use and mortality.International Journal of Clinical Pharmacology and Therapy 44 309-318
Boyer L, Travaglione S, Falzano L, Gauthier NC, Popoff MR, Lemichez E, Fiorentini C and Fabbri A (2003) Rac GTPase instructs NF-kB activation by conveying the SCF complex and IkBa to the ruffling membranes. Molecular Biology of the Cell 15 1124-1133
Boyle Jr EM, Canty Jr TG, Morgan EN, Yun W, Pohlman TH and Verrier ED (1999) Treating myocardial ischemia-reperfusion injury by targeting endothelial cell transcription. Annals of Thoracic Surgery 68 1949-1953
Boyle Jr EM, Kovacich JC, Canty Jr TG, Morgan EN, Chi E, Verrier ED and Pohlman TH (1998) Inhibition of Nuclear Factor-kB nuclear localization reduces human E-selectin expression and the systemic inflammatory response. Circulation 98 II282-II288
Boyman O, Conrad C, Dudli C, Kielhorn E, Nickoloff BJ and Nestle FO (2005) Activation of dendritic antigen-presenting cells expressing common heat shock protein receptor CD91 during induction of psoriasis. British Journal of Dermatology 152 1211-1218
Braam B, De Roos R, Dijk A, Boer P, Post JA, Kemmeren PP, Holstege FC, Bluyssen HA and Koomans HA (2004) Nitric oxide donor induces temporal and dose-dependent reduction of gene expression in human endothelial cells. Am J Physiol Heart Circ Physiol 287 H1977-H1986
Bracchi-Ricard V, Brambilla R, Levenson J, Hu WH, Bramwell A, Sweatt JD, Green EJ and Bethea JR (2007) Astroglial nuclear factor-kB regulates learning and memory and synaptic plasticity in female mice. Journal of Neurochemistry in press
Brach MA, de Vos S, Arnold C, Gruss H-J, Mertelsmann R and Herrmann F (1992) Involvement of nuclear factor-kB in induction of the interleukin-6 gene by leukemia inhibitory factor. European Journal of Immunology 22 2705-2711
Brach MA, Gruss HJ, Kaisho T, Asano Y, Hirano T and Herrmann F (1993) Ionizing radiation induces expression of interleukin 6 by human fibroblasts involving activation of Nuclear Factor-kB. Journal of Biological Chemistry 268 8466-8472
Brach MA, Gruss H-J, Riedel D, Mertelsmann R and Herrmann F (1992) Activation of NF-kB by interleukin 2 in human blood monocytes. Cell Growth & Differentiation 3 421-427
Brach MA, Hass R, Sherman ML, Gunji H, Weichselbaum R and Kufe D (1991) Ionizing radiation induces expression and binding activity of the nuclear factor-kB. Journal of Clinical Investigation 88 691-695
Brach MA, Henschler R, Mertelsmann RH and Herrmann F (1991) Regulation of M-CSF expression by M-CSF: role of protein kinase C and transcription factor NF-kB. Pathobiology 59 284-288
Brach MA, Kharbanda SM, Herrmann F and Kufe DW (1992) Activation of the transcription factor kB in human KG-1 myeloid leukemia cells treated with 1-b-D-arabinofuranosylcytosine. Molecular Pharmacology 41 60-63
Bracken CP, Whitelaw ML and Peet DJ (2005) Activity of hypoxia-inducible factor 2 alpha (HIF-2 a) is regulated by association with the NF-kB essential modulator (NEMO/IKKg). Journal of Biological Chemistry 280 14240-14251
Bradbrun JE, Pei P, Kresty LA, Lang JC, Yates AJ, McCromick AP and Mallery SR (2007) The effects of reactive species on the tumorigenic phenotype of human head and neck squamous cell carcinoma (HNSCC) cells. ANticancer Research 27 3819-3827
Bradbury DA, Newton R, Zhu YM, El-Haroun H, Corbett L and Knox AJ (2003) COX-2 induction by Bradykinin in human pulmonary artery smooth muscle cells is mediated by the cyclic AMP response element through a novel autocrine loop involving endogenous PGE2, EP2 and EP4 receptors. Journal of Biological Chemistry 278 49954-49964
Bradham CA, Hatano E and Brenner DA (2001) Dominant-negative TAK1 induces c-Myc and G(0) exit in liver. American Journal of Physiology: Gastrointestinal Liver Physiology 281 G1279-G1289
Bradham CA, Schemmer P, Stachlewitz RF, Thurman RG and Brenner DA (1999) Activation of nuclear factor-kB during orthotopic liver transplantation in rats is protective and does not require Kupffer cells. Liver Transpl Surg 5 282-293
Bradley EW and Oursler MJ (2008) Osteoclast culture and resorption assays. Methods in Molecular Biology 455 19-35
Bradley JR and Pober JS (2001) Tumor necrosis factor receptor-associated factors (TRAFS). Oncogene 20 6482-6491
Bradley RL, Fisher FM and Maratos-Flier E (2008) Dietary fatty acids differentially regulate production of TNF-a and IL-10 by murine 3T3-L1 adipocytes. Obesity (Silver Spring) in press
Bradley SV, Smith MR, Hyun TS, Lucas PC, Li L, Antonuk D, Joshi I, Jin F and Ross TS (2007) Aberrant huntingtin interacting protein 1 in lymphoid malignancies. Cancer Research 67 8923-8931
Brady K, Fitzgerald S, Ingvarsson S, Borrebaeck CA and Moynagh PN (2001) CD40 employs p38 MAP kinase in IgE isotype switching. Biochemical and Biophysical Research Communcations 289 276-281
Brady JN (1992) Extracellular Tax1 protein stimulates NF-kB and expression of NF-kB-responsive Ig k and TNFb genes in lymphoid cells. AIDS Research & Human Retroviruses 8 724-727
Braeuer SJ, Buneker C, Mohr A and Zwacka RM (2006) Constitutively activated nuclear factor-kB, but not induced NF-kB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells.Molecular Cancer Research 4 715-728
Bramachari S, Fung YK and Pahan K (2006) Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. Journal of Neuroscience 26 4930-4939
Brambilla R, Bracchi-Ricard V, Hu WH, Frydel B, Bramwell A, Karmally S, Green EJ and Bethea JR (2005) Inhibition of astroglial nuclear factor kB reduces inflammation and improves functional recovery after spinal cord injury. Journal of Experimental Medicine 202 145-156
Branca M, Ciotti M, Giorgi C, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Syrjanen S, Favalli C, Syrjanen K, the HPV-Pathogen ISS Study Group (2008) Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling. International Journal of Gynecological Pathology 27 265-273
Branca M, Giorgi C, Ciotti M, Santini D, Di Bonito L, Costa S, Benedetto A, Bonifacio D, Di Bonito P, Paba P, Accardi L, Mariani L, Ruutu M, Syrjanen S, Faavalli C and Syrjanen K (2006) Upregulation of nuclear factor-kappaB (NF-kB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer. Diagnostic Cytopathology 34 555-563
Brancho D, Ventura JJ, Jaeschke A, Doran B, Flavell RA and Davis RJ (2005) Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades. Molecular and Cellular Biology 25 3670-3681
Brand JM, Frohn C, Cziupka K, Brockmann C, Kirchner H and Luhm J (2004) Prolactin triggers pro-inflammatory immune responses in peripheral immune cells. European Cytokine Network 15 99-104
Brand K, Eisele T, Kreusel U, Page M, Page S, Haas M, Gerling A, Kaltschmidt C, Neumann F-J, Baeuerle PA, Walli AK and Neumeier D (1997) Dysregulation of monocytic nuclear factor kB by oxidized low density lipoprotein. Arterioscler Thromb Vasc Biol 17 1901-1909
Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R, Page M, Kaltschmidt C, Baeuerle PA and Neumeier D (1996) Activated transcription factor Nuclear Factor-kB is present in the atherosclerotic lesion. Journal of Clinical Investigation 97 1715-1722
Brand K, Page S, Walli AK, Neumeier D and Baeuerle PA (1996) Role of NF-kB in atherogenesis. Experimental Physiology 82 297-304
Brand SJ, Morise Z, Tagerud S, Mazzola L, Granger DN and Grisham MB (1999) Role of the proteasome in rat indomethacin-induced gastropathy. Gastroenterology 116 865-873
Brandes LM, Lin ZP, Patierno SR and Kennedy KA (2001) Reversal of physiological stress-induced resistance to topoisomerase II inhibitors using an inducible phosphorylation site-deficient mutant of IkBa. Molecular Pharmacology 60 559-567
Brando-Lima AC, Saldanha-Gama RF, Pereira CR, Villela CG, Sampaio AL, Monteiro-Moreira AC, Henriques MG, Moreira RA and Barja-Fidalgo C (2006) Involvement of phosphatidylinositol-3 kinase-Akt and nuclear factor kB pathways in the effect of frutalin on human lymphocyte. International Immunopharmacology 6 465-472
Brandon CI, Vandenplas M, Dookwah H, Linden J and Murray TF (2006) Cloning and pharmacological characterization of the equine adenosine A receptor: a potential therapeutic target for the treatment of equine endotoxemia. Journal ofVeterinary Pharmacology and Therapy 29 243-253
Brandon CI, Vandenplas M, Dookwah H and Murray TF (2006) Cloning and pharmacological characterization of the equine adenosine A receptor. Journal ofVeterinary Pharmacology and Therapy 29 255-263
Brandt JA, Churchill L, Rehman A, Ellis G, Memet S, Israel A and Krueger JM (2004) Sleep deprivation increases the activation of nuclear factor kB in lateral hypothalamic cells. Brain Research 1004 91-97
Brandt R and Krantz S (2006) Glycated albumin (Amadori product) induces activation of MAP kinases in monocyte-like MonoMac 6 cells. Biochimica etBiophysica Acta 1760 1749-1753
Brandt S, Kwok T, Hartig R, Konig W and Backert S (2005) NF-kB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proceedings of the National Academy of Sciences USA 102 9300-9305
Brantley DM, Chen CL, Muraoka RS, Bushdid PB, Bradberry JL, Kittrell F, Medina D, Matrisian LM, Kerr LD and Yull FE (2001) Nuclear Factor-kB (NF-kB) regulates proliferation and branching in mouse mammary epithelium. Molecular and Cellular Biology 12 1445-1455
Brantley E, Patel V, Stinson SF, Trapani V, Hose CD, Ciolino HP, Yeh GC, Gutkind JS, Sausville EA and Loaiza-Perez AI (2005) The antitumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces NF-kB activity in drug-sensitive MCF-7 cells. Anticancer Drugs 16 137-143
Brar SS, Kennedy TP, Sturrock AB, Huecksteadt TP, Quinn MT, Whorton AR andHoidal JR (2002) An NAD(P)H oxidase regulates growth and transcription in melanoma cells. Am J Physiol Cell Physiol 282 C1212-C1224
Brar SS, Kennedy TP, Quinn M and Hoidal JR (2003) Redox signaling of NF-kB by membrane NAD(P)H oxidases in normal and malignant cells. Protoplasma 221 117-127
Brar SS, Kennedy TP, Whorton AR, Sturrock AB, Huecksteadt TP, Ghio AJ and Hoidal JR (2001) Reactive oxygen species from NAD(P)H:quinone oxidoreductase constitutively activate NF-kB in malignant melanoma cells. American Journal of Physiology Cell Physiology 280 C659-C676
Brasier AR (2007) The NF-kB regulatory network. Cardiovascular Toxicology 6 111-130
Brasier AR, Jamaluddin M, Casola A, Duan W, Shen Q and Garofalo R (1998) A promoter recruitment mechanism for tumor necrosis factor-a-induced interleukin-8 transcription in type II pulmonary epithelial cells: Dependence on nuclear abundance of Rel A, NF-kB1, and c-Rel transcription factors. Journal of Biological Chemistry 273 3551-3561
Brasier AR, Li J and Wimbish KA (1996) Tumor necrosis factor activates angiotensinogen gene expression by the Rel A transactivator. Hypertension 27 1009-1017
Brasier AR, Lu M, Hai T, Lu Y and Boldogh I (2001) NF-kB-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kB1 residence. Journal of Biological Chemistry 276 32080-32093
Brasier AR, Ron D, Tate JE and Habener JF (1990) A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1a induced, NFkB mediated trans-activation of the angiotensinogen gene acute-phase response element. EMBO Journal 9 3933-3944
Brasil LJ, San-Miguel B, Kretzmann NA, Amaral JL, Zettler CG, Marroni N, Gonzalez-Gallego J and Tunon MJ (2006) Halothane induces oxidative stress and NF-kB activation in rat liver: protective effect of propofol. Toxicology 227 53-61
Brasse-Lagnel C, Lavoinne A, Fairand A, Vavasseur K and Husson A (2005) IL-1beta stimulates argininosuccinate synthetase gene expression through NF-kB in Caco-2 cells. Biochimie 87 403-409
Brasse-Lagnel C, Lavoinne A, Loeber D, Fairand A, Bole-Feysot C, Deniel N and Husson A (2007) Glutamine and interleukin-1beta interact at the level of Sp1 and nuclear factor-kB to regulate argininosuccinate synthetase gene expression. FEBS Journal 274 5250-5262
Brat DJ, Bellail AC and Van Meir EG (2005) The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro-oncology 7 122-133
Bratt J, Belcher J, Vercellotti GM and Palmblad J (2000) Effects of anti-rheumatic gold salts on NF-kB mobilization and tumour necrosis factor-alpha (TNF-alpha)-induced neutrophil-dependent cytotoxicity for human endothelial cells. Clinical and Experimental Immunology 120 79-84
Braun T, Carvalho G, Coquelle A, Vozenin MC, Lepelley P, Hirsch F, Kiladjian JJ, Ribrag V, Fenaux P and Kroemer G (2006) NF-kB constitutes a potential therapeutic target in high-risk myelodysplastic syndromes. Blood 107 1156-1165
Braun T, Carvalho G, Fabre C, Grosjean J, Fenaux P and Kroemer G (2006)Targeting NF-kB in hematologic malignancies. Cell Death and Differentiation 13 748-758
Braunschweig MH and Leeb T (2006) Aberrant low expression level of boving beta-lactoglobulin is associated with a C to A transversion in the BLG promoter region. Journal of Dairy Science 89 4414-4419
Braunstein S, Formenti SC and Schneider Rj (2008) Acquisition of stable inducible up-regulation of nuclear factor-kB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells. Molecular Cancer Research 6 78-88
Bravo J, Li Z, Speck NA and Warren AJ (2001) The leukemia-associated AML1 (Runx1)–CBF beta complex functions as a DNA-induced molecular clamp. Nature Structural Biology 8 371-378
Bravo R (1990) Growth factor-repsonsive genes in fibroblasts. Cell Growth & Differentiation 1 305-309
Bravo R, Zerial M, Toschi L, Schurmann R, Müller R, Hirai SI, Yaniv M, Almendral JM and Ryseck R-P (1988) Identification of growth-factor-inducible genes in mouse fibroblasts. Cold Spring Harbor Symposia on Quantitative Biology Volume LIII 901-905
Bravo SB, Pampin S, Cameselle-Teijeiro J, Carneiro C, Dominguez F, Barreiro F and Alvarez CV (2003) TGF-beta-induced apoptosis in human thyrocytes is mediated by p27(kip1) reduction and is overridden in neoplastic thyrocytes by NF-kB activation. Oncogene 22 7819-7830
Bravo Y, Quiroz Y, Ferrebuz A, Vaziri ND and Rodriguez-Iturbe B (2007) Mycopheolate mofetil administration reduces renal inflammation, oxidative stress and arterial pressure in rats with lead-induced hypertension. American Journal of Physiology: Renal Physiology 293 F616-F623
Brazier SP, Mason HS, Bateson AN and Kemp PJ (2005) Cloning of the human TASK-2 (KCNK5) promoter and its regulation by chronic hypoxia. Biochemical and Biophysical Research Communications 336 1251-1258
Brechter AB and Lerner UH (2007) Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Arthritis andRheumatism 56 910-919
Brechter AB, Persson E, Lundgren I and Lerner UH (2008) Kinin B1 and B2 receptor expression in osteoblasts and fibroblasts is enhanced by interleukin-1 and tumour necrosis factor-alpha. Effects dependent on activation of NF-kB and MAP kinases. Bone in press
Bredel M, Bredel C, Juric D, Duran GE, Yu RS, Harsh GR, Vogel H, Recht LD, Scheck AC and Sikic BI (2005) Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kB-mediated resistance to O6-alkylating agents in human glioblastomas. Journal of Clinical Oncology 24 274-287
Bregegere F, Milner Y and Friguet B (2006) The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care?
Ageing Research Reviews 4 60-90
Breiman A, Grandvaux N, Lin R, Ottone C, Akira S, Yoneyama M, Fujita T, Hiscott J and Meurs EF (2005) Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon. Journal of Virology 79 3969-3978
Breitkreutz I, Raab MS, Vallet S< Hideshima T, Raje N, Mitsiades C, Chauhan D, Okawa Y, Munshi NC, Richardson PG and ANderson KC (2008) Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma. Leukemia in press
Bremner P and Heinrich M (2002) Natural products as targeted modulators of the nuclear factor-kB pathway. Journal of Pharmacy and Pharmacology 54 453-472
Bremner P, Tang S, Birkmayer H, Fiebich BL, Munoz E, Marquez N, Rivera D and Heinrich M (2004) Phenylpropanoid NF-kB inhibitors from Bupleurum fruticosum. Planta Medica 70 914-918
Bren GD, Solan NJ, Miyoshi H, Pennington KN, Pobst LJ and Paya CV (2001) Transcription of RelB gene regulated by NF-kB. Oncogene 20 7722-7733
Bren GD, Whitman J, Cummins N, Shepard B, Rizza SA, Trushin SA and Badley AD (2008) Infected cell killing by HIV-1 protease promotes NF-kB dependent HIV-1 replication. PLoS One 3 e2112
Bren-Mattison Y, Meyer AM, Van Putten V, Li H, Kuhn K, Stearman R, Weiser-Evans M, Winn RA, Heasley LE and Nemenoff R (2008) Antitumorigenic effects of Peroxisome Proliferator-Activated Receptor-gamma (PPARgamma) in non-small cell lung cancer cells (NSCLC) are mediated by suppression of COX-2 via inhibition of NF-kB. Molecular Pharmacology 73 709-717
Brengauz-Breitmann M, Friedman E, Savion S, Torchinsky A, Fein A and Toder V (2006) Involvement of NF-kB in the response of embryonic cells to methotrexate.Reproductive Toxicology 22 469-478
Brenhoehl J, Herfarth H, Gluck T, Audebert F, Barlage S, Schmitz G, Froehlich D, Schreirber S, Hampe J, Scholmerich J, Holler E and Rogler G (2007) Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients. Intensive Care Medicine 33 1541-1548
Brennan CA, Delaney JR, Schneider DS and Anderson KV (2007) Psidin is required in Drosophila blood cells for both phagocytic degradation and immune activation of the fat body.
Current Biology 17 67-72
Brennan D, Hu Y, Joubeh S, Choi YS, Whitaker-Menezes D, O’Brien T, Uitto J, Rodeck U and Mahoney MG (2007) Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to keratinocytes. Journal of Cell Science 120 758-771
Brennan P (2001) Signalling events regulating lymphoid growth and survival. Seminars in Cancer Biology 11 415-421
Brennan P and O’Neill LA (1998) Inhibition of nuclear factor kB by direct modification in whole cells–mechanism of action of nordihydroguaiartic acid curcumin and thiol modifiers. Biochemical Pharmacology 55 965-973
Brennan P and O’Neill LAJ (1995) Effects of oxidants and antioxidants on nuclear factor kB activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals. Biochimica et Biophysica Acta 1260 167-175
Brenner D, Golks A, Becker M, Muller W, Frey CR, Novak R, Melamed D, Kiefer F, Krammer PH and Arnold R (2007) Caspase cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. Blood 110 3968-3977
Brenner D, Golks A, Kiefer F, Krammer PH and Arnold R (2005) Activation or suppression of NFkB by HPK1 determines sensitivity to activation-induced cell death. EMBO Journal 24 4279-4290
Brenner D, Krammer PH and Arnold R (2008) Concepts of activated T cell death. Critical Reviews in Oncology and Hematology in press
Bressler P, Brown K, Timmer W, Bours V, Siebenlist U and Fauci AS (1993) Mutational analysis of the p50 subunit of NF-kB and inhibition of NF-kB activity by trans-dominant p50 mutations. Journal of Virology 67 288-293
Bretschneider E, Kaufmann R, Braun M, Wittpoth M Glusa E, Nowak G and Schror K (1999) Evidence for proteinase-activated receptor-1 (PAR-2)-mediated mitogenesis in coronary artery smooth muscle cells. British Journal of Pharmacology 126 1735-1740
Brettingham-Moore KH, Rao S, Juelich T, Shannon MF and Holloway AF (2005) GM-CSF promoter chromatin remodelling and gene transcription display distinct signal and transcription factor requirements. Nucleic Acids Research 33 225-234
Breton JJ and Chabot-Fletcher MC (1997) The natural product hymeialdisine inhibits interleukin-8 production in U937 cells by inhibition of nuclear factor-kB. Journal of Pharmacology and Experimental Therapy 282 459-466
Bretschneider E, Kaufmann R, Braun M, Wittpoth M, Glusa E, Nowak G and Schror K (1999) Evidence for proteinase-activated receptor-2 (PAR-2)-mediated mitogenesis in coronary artery smooth muscle cells. British Journal of Pharmacology 126 1735-1740med&dopt=Abstract&list_uids=15650393Breuer-McHam J, Simpson E, Dougherty I, Bonkobara M and Ariizumi K, Lewis DE, Dawson DB, Duvic M and Cruz PD Jr (2002) Activation of HIV in human skin by ultraviolet B radiation and its inhibition by NFkB blocking agents. Photochem Photobiol 74 805-810
Breuzard G, Tertil M, Goncalves C, Cheradame H, Geguan P, PIchon C and Midoux P (2008) Nuclear delivery of NF{kappa}B-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging. Nucleic Acids Research in press
Briant L, Reynes J, Coudronniere N, Benezech JP and Devaux C (1999) HIV-1 reactivation in resting peripheral blood mononuclear cells of infected adults upon in vitro CD4 cross-linking by ligands of the CDR2-loop in extracellular domain 1. Journal of Acquired Immune Deficiency Syndrome 21 9-19
Briant L, Robert-Hebman V, Acquaviva C, Pelchen-Matthews A, Marsh M and Devaux M (1998) The protein kinase p56 is required for triggering NF-kB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4. Journal of Virology 72 6207-6214
Briassouli P, Chan F, Savage K, Reis-Filho JS and Linardopoulos S (2007) Aurora-A regulation of nuclear factor-kB signaling by phosphorylation of IkBalpha.Cancer Research 67 1689-1695
Brickley P (2002) New patent worries professors. The Scientist 16 19
Brickman JM, Adam M and Ptashne M (1999) Interactions between an HMG-1 protein and members of the Rel family. Proceedings of the National Academy of Sciences USA 96 10679-10683
Bridges JP, Xu Y, Na CL, WOng HR and Weaver TE (2006) Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C. Journal of Cell Biology 172 395-407
Briegel K, Hentsch B, Pfeuffer I and Serfling E (1991) One base change abolished the T cell-restricted activity of kB-like proto-enhancer element from IL-2 promoter. Nucleic Acids Research 21 5929-5936
Briganti S and Picardo M (2003) Antioxidant activity, lipid peroxidation and skin diseases. What’s new. J Eur Acad Dermatol Venereol 17 663-669
Brigelius-Flohe R (2006) Glutathione peroxidases and redox-regulated transcription factors. Biol Chem 387 1329-1335
Bright JJ (2007) Curcumin and autoimmune disease. Advances in Experimental Medicine and Biology 595 425-451
Bright JJ, Kanakasabai S, Chearwae W, Chakraborty S (2008) PPAR regulation of inflmmatory signaling in CNS diseases. PPAR Research in press
Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ and Modlin RL (1999) Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 285 732-736
Bringmann A, Schmidt SM, Weck MM, Brauer KM, von Schwarzenberg K, Werth D, Grunebach F and Brossart P (2007) Zoledronic acid inhibits the function of Toll-like receptor 4 ligand activated monocyte-derived dendritic cells. Leukemia 21 732-738
Brini AT, Harel-Bellan A and Farrar WL (1990) Cyclosporin A inhibits indiction of IL-2 receptor a chain expression by affecting activation of NF-kB-like factor(s) in cultured human T lymphocytes. European Cytokine Network 1 131-139
Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C and Schulz TF (2003) Activation of mitogen-activated protein kinase and NF-kB pathways by a Kaposi’s Sarcoma-Associated Herpesvirus K15 membrane protein. Journal of Virology 77 9346-9358
Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M and Schulz TF (2006) Modulation of host gene expression by the K15 protein of Kaposi sarcoma-associated herpesvirus. Journal of Virology 81 42-58
Brint EK, Fitzgerald KA, Smith P, Coyle AJ, Gutierrez-Ramos JC, Fallon PG and O’Neill LA (2002) Characterisation of signalling pathways activated by the IL-1 receptor homologue T1/ST2: A role for Jun N-terminal kinase in IL-4 induction. Journal of Biological Chemistry 277 49205-49211
Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O’Neill LA and Liew FY (2004) ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nature Immunology 5 373-379
Briot D, Mace-Aime G, Subra F and Rosselli F (2007) Aberrant activation of stress-response pathways leads to TNF-a oversecretion in Fanconi anemia. Blood in press
Briscoe T, Duncan J, Cock M, Choo J, Rice G, Harding R, Scheerlinck JP and Rees S (2006) Activation of NF-kB transcription factor in the preterm ovine brain and placenta after acute LPS exposure. Journal of Neuroscience Research 83 567-574
Brisslert M, Bokarewa M, Larsson P, Wing K, Collins LV, Tarkowski A (2006) Phenotypic and functional characterization of human CD25 B cells. Immunology 117 548-557
Bristow CL, Wolkowicz R, Trucy M, Franklin A, Di Meo F, Kozlowski MT, Winston R and Arnold RR (2008) NF-kB signaling, elastase localization, and phagocytosis differ in HIV-1 permissive and nonpermissive U937 clones. Journal of Immunology 180 492-499
Britanova LV, Makeev VJ and Kuprash DV (2008) In vitro selection of optimal RelB/p52 DNA-binding motifs. Biochemical and Biophysical Research Communications365 583-588
Broad A, Kirby JA, Jones DE, and the Applied Immunology and Transplantation Research Group (2007) Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production. Immunology 120 103-111
Brochu S, Olivier M and Rivest S (1999) Neuronal activity and transcription of proinflammatory cytokines, IkBa, and iNOS in the mouse brain during acute endotoxemia and chronic infection with Trypanosoma brucei brucei. Journal of Neuroscience Research 57 801-816
Brocke-Heidrich K, Ge B, Cvijic H, Pfeifer G, Loffler D, Henze C, McKeithan TW and Horn F (2006) BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription. Oncogene 7297-7304
Brockman D, Pützer BM, Lipinski KS, Schmücker U and Esche H (1999) A multiprotein complex consisting of the cellular coactivator p300, AP-1/ATF, as well as NF-kB is responsible for the activation of the mouse major histocompatibility class I (H-2Kb) enhancer A. Gene Expression 8 1-18
Brockman JA, Sherer DC, McKinsey TA, Hall SA, Qi X, Lee WH and Ballard DW (1995) Coupling of a signal response domain in IkBa to multiple pathways for NF-kB activation. Molecular and Cellular Biology 15 2809-2818
Broderick L and Bankert RB (2006) Membrane-associated TGF-beta1 inhibits human memory T cell signaling in malignant and nonmalignant inflammatory microenvironments. Journal of Immunology 177 3082-3088
Broderick L, Brooks SP, Takita H, Baer AN, Bernstein JM and Bankert RB (2005) IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells. Clinical Immunology 118 159-160
Brody JS and Spira A (2006) State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer.
Proceedings of the American Thoracic Society 3 535-537
Broemer M, Krappmann D and Scheidereit C (2004) Requirement of Hsp90 activity for IkB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kB activation. Oncogene 23 5378-5386
Brogan IJ, Murray IA, Cerillo G, Needham M, White A and Davis JR (1999) Interaction of glucocorticoid receptor isoforms with transcription factors AP-1 and NF-kB: lack of effect of glucocorticoid receptor beta. Molecular and Cellular Endocrinology 157 95-104
Broide DH, Lawrence T, Doherty T, Cho JY, Miller M, McElwain K, McElwain S and Karin M (2005) Allergen-induced peribronchial fibrosis and mucus production mediated by IkB kinase beta-dependent genes in airway epithelium. Proceedings of the National Academy of Sciences USA 102 17723-17728
Bronisz A, Sharma SM, Hu R, Godlewski J, Tzivion G, Mansky KC and Ostrowski MC (2006) Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursors. Molecular Biology of the Cell 17 3897-3906
Brooks AR, Lelkes PI and Rubanyi GM (2002) Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow. Physiol Genomics 9 27-41
Brooks DG, Arlen PA, Gao L, Kitchen CM and Zack JA (2003) Identification of T cell-signaling pathways that stimulate latent HIV in primary cells. Proceedings of the National Academy of Sciences USA 100 12955-12960
Brooks PA, Cockerell GL and Nyborg JK (1998) Activation of BLV transcription by NF-kB and Tax. Virology 243 94-98
Brooks PA, Nyborg JK and Cockerell GL (1995) Identification of an NF-kB binding site in the bovine leukemia virus promoter. Journal of Virology 69 6005-6009
Brooks SV, Vasilaki A, Larkin LM, McArdle A and Jackson MJ (2008) Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and NFkB activation. Journal of Physiology in press
Broome CS, Kayani AC, Palomero J, Dillmann WH, Mestril R, Jackson MJ and McArdle A (2006) Effect of lifelong overexpression of HSP70 in skeletal muscle on age-related oxidative stress and adaptation after nondamaging contractile activity.FASEB Journal 20 1549-1551
Brosman MJ and Carkner RD (2008) Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive rat. American Journall of Hypertenstion in press
Brostjan C, Anrather J, Csizmadia V, Stroka D, Soares M, Bach FH and Winkler H (1996) Glucocorticoid-mediated repression of NFkB activity in endothelial cells does not involve induction of IkBa synthesis. Journal of Biological Chemistry 271 19612-19616
Brouard S, Berberat PO, Tobiasch E, Seldon MP, Bach FH and Soares MP (2002) Heme oxygenase-1 derived carbon monoxide requires the activation of the transcription factor NF-kB to protect endothelial cells from TNF-alpha mediated apoptosis. Journal of Biological Chemistry 277 17950-17961
Brouduer SR, Cheng G, Baltimore D and Thorley-Lawson DA (1997) Localization of the major NF-kB-activating site and the sole TRAF3 binding site of LMP-1 defines two distinct signaling motifs. Journal of Biological Chemistry 272 19777-19784
Brouillard F, Bouthier M, Leclerc T, Clement A, Baudouin-Legros M and Edelman A (2001) NF-kB mediates up-regulation of CFTR gene expression in Calu-3 cells by interleukin-1beta. Journal of Biological Chemistry 276 9486-9491
Browatzki M, Larsen D, Pfeiffer CA, Gehrke SG, Schmidt J, Kranzhofer A, Katus HA and Kranzhofer R (2005) Angiotensin II stimulates matrix metalloproteinase secretion in human vascular smooth muscle cells via nuclear factor-kB and activator protein 1 in a redox-sensitive manner. Journal of Vascular Research 42 415-423
Browatzki M, Pfeiffer CA, Schmidt J and Kranzhofer R (2005) Endothelin-1 induces CD40 but not IL-6 in human monocytes via the proinflammatory transcription factor NF-kB. European Journal of Medical Research 10 197-201
Browatzki M, Pfeiffer CA, Schmidt J and Kranzhofer R (2007) Endothelin-1 induces functionally active CD40 protein via nuclear factor-kB in human vascular smooth muscle cells.
European Journal of Medical Research 12 129-133
Browder W, Ha T, Chuanfu L, Kalbfleisch JH, Ferguson Jr DA and Williams DL (1999) Early activation of pulmonary nuclear factor kB and nuclear factor interleukin-6 in polymicrobial sepsis. Journal of Trauma 46 590-596
Brower V (2005) Feeding the flame: new research adds to role of inflammation in cancer development. Journal of the National Cancer Institute 97 251-2253
Brown AG, Leite R and Strauss JF 3rd (2005) Mechanisms underlying “functional” progesterone withdrawal at parturition. Annals of the New York Academy of Sciences 1034 36-49
Brown AM, Linhoff MW, Stein B, Wright KL, Baldwin Jr AS, Basta PV and Ting JP-Y (1994) Function of NF-kB/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kB/Rel subunits. Molecular and Cellular Biology 14 2926-2935
Brown C, Gaspar J, Pettit A, Lee R, Gu X, Wang H, Manning C, Voland C, Goldring SR, Goldring MB, Libermann TA, Gravalllese EM and Oettgen P (2004) ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. Journal of Biological Chemistry 279 12794-12803
Brown DM, Beswick PH and Donaldson K (1999) Induction of nuclear translocation of NF-kB in epithelial cells by respirable mineral fibres. Journal of Pathology 189 258-264
Brown DM, Donaldson K, Borm PJ, Schins PR, Denhart M, Gilmour P, Jimenez LA and Stone V (2004) Calcium and reactive oxygen species-mediated activation of transcription factors and TNFa cytokine gene expression in macrophages exposed to ultrafine particles. American Journal of Physiology: Lung Cell and Molecular Physiology 286 L344-L353
Brown HJ, Song MJ, Deng H, Wu TT, Cheng G and Sun R (2003) NF-kB inhibits gammaherpesvirus lytic replication. Journal of Virology 77 8532-8540
Brown JH, Del Re DP and Sussman MA (2006) The Rac and Rho hall of fame: a decade of hypertrophic signaling hits. Circulation Research 98 730-742
Brown K, Franzoso G, Baldi L, Carlson L, Mills L, Lin Y-C, Gerstberger S and Siebenlist U (1997) The signal response of IkB-a is regulated by transferable N- and C-terminal domains. Molecular and Cellular Biology 17 3021-3027
Brown K, Gerstberger S, Carlson L, Franzoso G and Siebenlist U (1995) Control of IkB-a proteolysis by site-specific, signal-induced phosphorylation. Science 267 1485-1488
Brown K, Park S, Kanno T, Franzoso G and Siebenlist U (1993) Mutual regulation of the transcriptional activator NF-kB and its inhibitor, IkB-a. Proceedings of the National Academy of Sciences USA 90 2532-2536
Brown KL, Bylund J, MacDonald KL, Song-Zhao GX, Elliott MR, Falsafi R, Hancock RE, Speert DP (2008) ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disoreders of chronic granulomatous disease.Clinical Immunology 129 90-102
Brown M, McGuinness M, Wright T, Ren X, Wang Y, Boivin GP, Hahn H, Feldman AM and Jones WK (2005) Cardiac-specific blcokade of NF-kB in cardiac pathophysiology: differences between acute and chronic stimuli in vivo. American Journal of Physiology: Heart and Circulatory Physiology 289 H466-H476
Brown RE (2005) The NF-kB pathway and the successful application of anti-inflammatory and angiostatic therapy in Langerhans’ cell histiocytosis. British Journal of Haematology 130 147-148
Brown RE and Law A (2006) Morphoproteomic demonstration of constitutive nuclear factor-kB activation in glioblastoma multiforme with genomic correlates and therapeutic implications. Annals of Clinical Laboratory Science 36 421-426
Brown RE, Tan D, Taylor JS, Miller M, Prichard JW and Kott MM (2007) Morphoproteomic confirmation of constitutively activated mTOR, ERK, and NF-kB pathways in high risk neuroblastoma, with cell cycle and protein analyte correlates. Annals of Clinical and Laboratory Science 37 141-147
Brown RE, Zhang PL, Lun M, Zhu S, Pellitteri PK, Law A, Wood GC and Kennedy TL (2006) Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma. Annals of Clinical Labortatory Science 36 273-282
Brown SA, Richards CM, Hanscom HN, Feng SL and Winkles JA (2003) The Fn14 cytoplasmic tail binds tumor necrosis factor receptor-associated factors 1,2,3 and 5 and mediates nuclear factor-kB activation. Biochemical Journal 371 395-403
Brown WM, Sasson A, Bellew DR, Hunsaker LA, Martin S, Leitao A, Deck LM, Vander Jagt DL, Oprea TI (2008) Efficeint calculation of molecular properties from simulation using kernel molecular dynamics. Journal of Chemical Informatics Modeling 48 1626-1637
Browne EP and Shenk T (2003) Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells. Proceedings of the National Academy of Sciences USA 100 11439-11444
Brownell E, Fell HP, Tucker PW, Geurts van Kessel AHM, Hagemeijer A and Rice NR (1988) Regional localization of the human c-rel locus using translocation chromosome analysis. Oncogene 2 527-529
Brownell E, Kozak CA, Fowle JR, Modi WS, Rice NR and O’Brien SJ (1987)Comparative genetic mapping of cellular rel sequences in man, mouse, and the domestic cat. American Journal of Genetics 39 194-202
Brownell E, Mathieson B, Young HA, Keller J, Ihle JN and Rice NR (1987) Detection of c-rel-related transcripts in mouse hematopoietic tissues, fractionated lymphocyte populations, and cell lines. Molecular and Cellular Biology 7 1304-1309
Brownell E, Mittereder N and Rice NR (1989) A human rel proto-oncogene cDNA containing anAlu fragment as a potential coding exon. Oncogene 4 935-942
Brownell E, O’Brien SJ, Nash WG and Rice NR (1985) Genetic characterization of human c-rel sequences. Molecular and Cellular Biology 5 2826-2831
Brownell E, Ruscetti FW, Smith RG and Rice NR (1988) Detection of rel-related RNA and protein in human lymphoid cells. Oncogene 3 93-98
Browning DD, Pan Z, Prossnitz ER and Ye RD (1997) Cell type- and developmental stage-specific activation of NF-kB by fMet-Leu-Phe in myeloid cells. Journal of Biological Chemistry 272 7995-8001
Brozovic S, Sahoo R, Barve S, Shiba H, Uriarte S, Blumberg RS and Kinane DF (2006) Porphyromonas gingivalis enhances FasL expression via up-regulation of NFkB-mediated gene transcription and induces apoptotic cell death in human gingival epithelial cells. Microbiology 152 797-806
Bruce-Keller AJ, Barger SW, Moss NI, Pham JT, Keller JN and Nath A (2001) Pro-inflammatory and pro-oxidant properties of the HIV protein Tat in a microglial cell line: attenuation by 17 beta-estradiol. Journal of Neurochemistry 78 1315-1324
Bruchhausen S, Zahn S, Valk E, Knop J and Becker D (2003) Thiol antioxidants block the activation of antigen-presenting cells by contact sensitizers. Journal of Investigative Dermatology 121 1039-1044
Bruck R, Aeed H, Avni Y, Shirin H, Matas Z, Shahmurov M, Avinoach I, Zozulya G, Weizman N and Hochman A (2004) Melatonin inhibits nuclear factor kB activation and oxidative stress and protects against thioacetamide induced liver damage in rats. Journal of Hepatology 40 86-93
Bruck R, Aeed H, Brazovsky E, Noor T and Hershkoviz R (2005) Allicin, the active component of garlic, prevents immune-mediated, concanavalin A-induced hepatic injury in mice. Liver International 25 613-621
Bruck R, Schey R, Aeed H, Hochman A, Genina O and Pines M (2004) A protective effect of pyrrolidine dithiocarbamate in a rat model of liver cirrhosis. Liver International 24 169-176
Bruckner AL (2004) Incontinentia pigmenti: a window to the role of NF-kB function. Seminars in Cutaneous Medical Surgery 23 116-124
Bruder JT, Heidercker G, Tan T-H, Weske JC, Derse D and Rapp UR (1993) Oncogene activation of HIV-LTR-driven expression via NF-kB binding sites. Nucleic Acids Research 21 5229-5234
Brueckmann M, Hoffmann U, Dvortsak E, Lang S, Kaden JJ, Borggrefe M and Haase KK (2004) Drotrecogin alfa (activated) inhibits NF-kB activation and MIP-1-alpha release from isolated mononuclear cells of patients with severe sepsis. Inflammation Research 53 528-533
Brueckmann M, Marx A, Martin Weiler H, Liebe V, Lang S, Kaden JJ, Zieger W, Borggrefe M, Huhle G and Konstantin Haase K (2003) Stabilization of monocyte chemoattractant protein-1-mRNA by activated protein C. Thromb Haemost 89 149-160
Bruey JM, Bruey-Sedano N, Newman R, Chandler S and Reed JC (2004) PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kB and caspase-1 activation in macrophages. Journal of Biological Chemistry 279 51897-51907
Bruggeman LA, Adler SH and Klotman PE (2001) Nuclear factor-kappa B binding to the HIV-1 LTR in kidney: implications for HIV-associated nephropathy. Kidney International 59 2174-2181
Bruggia-Prevot V, Sevalle J, Rossner S, and Checler F (2008) NFkB-dependent control of BACE1 promoter transactivation by Abeta 42. Journal of Biological Chemistry in press
Brule S, Charnaux N, Sutton A, Ledoux D, Chaigneau D, Saffar L and Gattegno L (2006) The shedding of syndecan-4 and syndecan-1 from HeLa cells and human primary macrophages is accelerated by SDF-1/CXCL12 and mediated by the Matrix Metalloproteinase-9.
Glycobiology in press
Brummelkamp TR, Nijman SMB, Dirac AMG and Bernards R (2003) Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kB. Nature 424 797-801
Brummer E, Choi JH and Stevens DA (2005) Interaction between conidia, lung macrophages, immunosuppressants, proinflammatory cytokines and transcriptional regulation. Medical Mycology 43 S177-S179
Brun J (2008) Proteasome inhibition as a novel therapy in treating rheumatoid arthritis. Medical Hypotheses in press
Brundage SI, Schreiber MA, Holcomb JB, Zautke N, Mastrangelo MA, Xq X, Macaitis J and Tweardy DJ (2003) Amplification of the proinflammatory transcription factor cascade increases with severity of uncontrolled hemorrhage in swine(1)(2). Journal of Surgical Research 113 74-80
Brunelleschi S, Bardelli C, Amoruso A, Gunella G, Ieri F, Romani A, Malorni W and Franconi F (2007) Minor polar compounds extra-virgin olive oil extract (MPC-OOE) inhibits NF-kB translocation in human monocyte/macrophages. Pharmacology Research in press
Brunn GJ, Saadi S and Platt JL (2006) Differential regulation of endothelial cell activation by complement and interleukin 1a. Circulation Research in press
Bruno M, Borchers C, Dial J, Walker N, Hartis J, Wetmore B, Carl Barrett J, Tomer K and Alex Merrick B (2002) Effects of TCDD upon IkB and IKK subunits localized in microsomes by proteomics. Archives of Biochemistry and Biophysics 406 153
Bruno ME and Kaetzel CS (2005) Long-term exposure of the HT-29 human intestinal epithelial cell line to TNF causes sustained up-regulation of the polymeric Ig receptor and proinflammatory genes through transcriptional and posttranscriptional mechanisms. Journal of Immunology 174 7278-7284
Bruno T, Iezzi S, De Nicola F, Di Padova M, Desantis A, Scarsella M, di Certo MG, Leonetti C, Floridi A, Passananti C and Fanciulli M (2008) Che-1 activates XIAP expression in response to DNA damage. Cell Death and Differentiation 15 515-520
Bruns B, Maass D, Barber R, Horton J and Carlson D (2008) Aletations in the cardiac inflammatory response to burn trauma in mice lacking a functional Toll-like receptor 4 gene. Shock in press
Bruysters M, Pertz HH, Teunissen A, Bakker RA, Gillard M, Chatelain P, Schunack W, Timmerman H and Leurs R (2004) Mutational analysis of the histamine H(1)-receptor binding pocket of histaprodifens. European Journal of Pharmacology 487 55-63
Bryan B, Kumar V, Stafford LJ, Cai Y, Wu G and Liu M (2004) GEFT, a Rho-family guanine nucleotide exchange factor, regulates neurite outgrowth and dendritic spine formation. Journal of Biological Chemistry 279 45824-45832
Bryan RG, Li Y, Lai J-H, Van M, Rice NR, Rich RR and Tan T-H (1994) The effect of CD28 signal transduction on c-Rel in human peripheral blood T cells. Molecular and Cellular Biology 14 7933-7942
Bryce PJ, Oyoshi MK, Kawamato S, Oettgen HC and Tsitsikov EN (2005) TRAF1 regulates Th2 differentiation, allergic inflammation and nuclear localization of the Th2 transcription factor, NIP45. International Immunology in press
Bryk J, Hardouin E, Pugach I, Hughes D, Strotmann R, Stoneking M and Myles S (2008) Positive selection in East Asians for an EDAR allele that enhances NF-kB activation. PLoS ONE 21 3 e2209
Brzoska T, Kalden DH, Scholzen T and Luger TA (1999) Molecular basis of the alpha-MSH/IL-1 antagonism. Annals of the New York Academy of Sciences 885 230-238
Brzoska T, Luger TA, Maaser C, Abels C and Bohm M (20080 a-melanocyte-stimulating hormone and related tripeptides: biochemistry, anti-inflammatory and protective effects in vitro and in vivo and future perspectives for the treatment of immune-mediated inflammatory diseases. Endocrine Reviews in press
Bu DX, Erl W, de Martin R, Hansson GK and Yan ZQ (2005) IKKbeta-dependent NF-kB pathway controls vascular inflammation and intimal hyperplasia. FASEB Journal 19 1293-1295
Bu DX, Hemdahl AL, Gabrielsen A, Fuxe J, Zhu C, Eriksson P and Yan ZQ (2006) Induction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-kB. American Journal of Pathology 169 2245-2253
Bu G, Lu W, Liu CC, Selander K, Yoneda T, Hall C, Keller Et and Li Y (2008) Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases. International Journal of Cancer in press
Bu P, Gao L, Zhuang J, Feng J, Yang D and Yan X (2006) Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kB activation. Molecular Cancer Therapeutics 5 2872-2878
Bu P, Zhuang J, Feng J, Yang D, Shen X and Yan X (2007) Visualization of CD146 dimerization and its regulation in living cells. Biochimica et Biophysica Actain press
Bu PL, Zhao XQ, Wang LL, Zhao YX, Li CB and Zhang Y (2008) Tong-xin-luo capsule inhibits left ventricular remodeling in spontaneously hypertensive rats by enhancing PPAR-g expression and suppressing NF-kB activity. Chinese Medical Journal 121 147-154
Bu S, Yamanaka M, Pei H, Bielawaska A, Bielawaski J, Hannun YA, Obeid L and Trojanowska M (2005) Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts. FASEB Journal 20 184-186
Bu SY, Lerner M, Stoecker BJ, Boldrin E, Brackett DJ, Lucas EA and SMith BJ (2008) Dried plum polyphenols inhibit osteoclastogenesis by downregulating NFATc1 and inflammatory mediators. Calcif Tissue International in press
Bubici C, Papa S, Dean K and Franzoso BG (2006) Mutual cross-talk between reactive oxygen species and nuclear factor-kB: molecular basis and biological significance.
Oncogene 25 6731-6748
Bubici C, Papa S, Pham CG, Zazzeroni F and Franzoso BG (2005) The NF-kB-mediated control of ROS and JNK signaling. Histology and Histopathology 21 69-80
Bubici C, Papa S, Pham CG, Zazzeroni F and Franzoso G (2004) NF-kB and JNK: an intricate affair. Cell Cycle 3 1524-1529
Buccelletti F, Mazzone M, Portale G, Forte P, Bono-Ni F, Mirabella C, Travaglino F and Gentiloni Silveri N (2003) Humoral and cellular inflammatory mediators in acute lung injury: friends or enemies? [Article in Italian]. Minerva Med 94 157-165
Buchan AM, Li H and Blackburn B (2000) Neuroprotection achieved with a novel proteasome inhibitor which blocks NF-kB activation. Neuroreport 11 427-430
Buchau AS, Schauber J, Hultsch T, Stuetz A and Gallo RL (20080 Pimecrolimus enhances TLR2/6-induced expression of antimicrobial peptides in keratinocytes. Journal of Investigative Dermatology in press
Bucher BT, Feng X, Jeyabalan G, Zhang B, Shao L, Guo Z and Geller DA (2006) Glycochenodeoxycholate (GCDC) inhibits cytokine induced iNOS expression in rat hepatocytes. Journal of Surgical Research in press
Buchholz TA, Garg AK, Chakravarti N, Aggarwal BB, Esteva FJ, Kuerer HM, Singletary SE, Hortobagyi GN, Puxztai L, Cristofanilli M and Sahin AA (2005) The nuclear transcription factor kB/bcl-2 pathway correlates with pathologic complete response to doxorubicin-based neoadjuvant chemotherapy in human breast cancer. Clinical Cancer Research 11 8398-8402
Buchmann A, Willy C, Buenemann CL, Stroh C, Schmiechen A and Schwarz M (1999) Inhibition of transforming growth factor beta1-induced hepatoma cell apoptosis by liver tumor promoters: characterization of primary signaling events and effects on CPP32-like caspase activity. Cell Death & Differentiation 6 190-200
Buckanovich RJ, Sasaroli D, O’Brien-Jenkins A, Botbyl J, Conejo-Garcia JR, Benencia F, Liotta LA, Gimotty PA and Coukos G (2006) Use of immuno-LCM to identify the in situ expression profile of cellular constituents of the tumor microenvironment. Cancer Biology and Therapeutics 5 635-642
Bucki R, Georges PC, Expinassous Q, Funaki M, Pastore JJ, Chaby R and Janmey PA (2005) Inactivation of endotoxin by human plasma gelsolin. Biochemistry 44 9590-9597
Bucki R, Sostarecz AG, Byfield FJ, Savage PB and Janmey PA (2007) Resistance of the antibacterial agent ceragenin CSA-13 to inactivation by DNA or F-actin and its activity in cystic fibrosis sputum. Journal of Antimicrobial Chemotherapy in press
Buckley RH (2004) Pulmonary complications of primary immunodeficiencies. Paediatr Respir Rev 5 S225-S233
Buckner AE and Dix RD (2006) Nicotine treatment alters NF-kB expression in human cytomegalovirus-infected ARPE-19 cells.
Current Eye Research 31 191-198
Buczynski MW, Stepens DL, Bowers-Gentry RC, Grkovich A, Deems RA and Dennis EA (2007) TLR-4 and sustained calcium agonists synergistically produce eicosanoids independant of protein synthesis in RAW264.7 cells. Journal of BiologicalChemistry in press
Budd RC, Yeh WC and Tschopp J (2006) cFLIP regulation of lymphocyte activation and development. Nature Reviews Immunology 6 196-204
Buddenkotte J, Stroh C, Engels IH, Moormann C, Shpacovitch VM, Seeliger S, Vergnolle N, Vestweber D, Luger TA, Schulze-Osthoff K and Steinhoff M (2005) Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kB. Journal of Investigative Dermatology 124 38-45
Budunova IV, Kowalczyk D, Perez P, Yao YJ, Jorcano JL and Slaga TJ (2003) Glucocorticoid receptor functions as a potent suppressor of mouse skin carcinogenesis. Oncogene 22 3279-3287
Budunova IV, Perez P, Vaden VR, Spiegelman VS, Slaga TJ and Jorcano JL (1999) Increased expression of p50-NF-kB and constitutive activation of NF-kB transcription factors during mouse skin carcinogenesis. Oncogene 18 7423-7431
Bueno C Lemke CD, Creiado G, Baroja ML, Ferguson SS, Rahman AK, Tsoukas CD, McCormick JK and Madrenas J (2006) Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway.
Immunity 25 67-78
Buerki C, Rothigiesser KM, Valovka T, Owen HR, Rehrauer H, Fey M Lane WS and Hottiger MO (2008) Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Research in press
Bueso-Ramos CE, Rocha FC, Shishodia S, Medeiros LJ, Kantarjian HM, Vadhan-Raj S, Estrov Z, Smith TL, Nguyen MH and Aggarwal BB (2004) Expression of constitutively active Nuclear-kB RelA transcription factor in blasts of acute myeloid leukemia. Human Pathology 35 246-253
Buettner M, Meyer B, Schreck S and Niedobitek G (2007) Expression of RANTES and MCP-1 in epithelial cells is regulated via LMP1 and CD40. International Journal of Cancer 121 2703-2710
Bugajska U, Georgopoulos NT, Southgate J, Johnson PW, Graber P, Gordon J, Selby PJ and Trejdosiewicz LK (2002) The effects of malignant transformation on susceptibility of human urothelial cells to CD40-mediated apoptosis. Journal of the National Cancer Institute 94 1381-1395
Bugarrski D, Krstic A, Mojsilovic S, Vlaski M, Petakov M, Jovcic G, Stojanovic N and Milenkovic P (2007) Signaling pathways implicated in hematopoietic progenitor cell proliferation and differentiation. Experimental Biology and Medicine (Maywood) 232 156-163
Buggins AG, Milojkovic D, Arno MJ, Lea NC, Mufti GJ, Thomas NS and Hirst WJ (2001) Microenvironment produced by acute myeloid leukemia cells prevents T cell activation and proliferation by inhibition of NF-kB, c-Myc, and pRb pathways. Journal of Immunology 167 6021-6030
Buhler OT, Wiedig CA, Schmid Y, Grassl GA, BOhn E and AUtenrieth IB (2006) The Yersinia enterocolitica invasin protein promotes major histocompatibility complex class I- and class II-restricted T-cell responses. Infection and Immunity 744322-4329
Bui NT, Livolsi A, Peyron JF and Prehn JH (2001) Activation of nuclear factor kB and Bcl-x survival gene expression by nerve growth factor requires tyrosine phosphorylation of IkappaBalpha. Journal of Cell Biology 152 753-764
Bukowski RM, Rayman P, Uzzo R, Bloom T, Sandstrom K, Peereboom D, Olencki T, Budd GT, McLain D, Elson P, Novick A and Finke JH (1998) Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy. Clincal Cancer Research 4 2337-2347
Bukulmez O, Hardy DB, Carr BR, Word RA and Mendelson CR (2007) Inflammatoty status influences aromatse and steroid receptor expression in endometriosis. Endocrinology in press
Bulger EM, Gourlay D, Cuschieri J, Jelacic S, Staudenmeyer K, Garcia I, Maier RV (2003) Platelet-activating factor acetylhydrolase inhibits alveolar macrophage activation in vivo. Shock 20 17-22
Bull P, Hunter T and Verma IM (1989) Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts. Molecular and Cellular Biology 9 5239-5243
Bull P, Morley KL, Hoekstra MF, Hunter T, and Verma IM (1990) The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Molecular and Cellular Biology 10 5473-5485
Bullock GC, Thrower AR and Stinski MF (2002) Cellular Proteins Bind to Sequence Motifs in the R1 Element between the HCMV Immune Evasion Genes. Exp Mol Pathol 72 196-206
Bulut Y, Faure E, Thomas L, Equils O and Arditi M (2001) Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. Journal of Immunology 167 987-994
Bulut Y, Michelsen KS, Hayrapetian L, Naiki Y, Spallek R, Singh M and Arditi M (2005) Mycobacterium tuberculosis heat shock proteins use diverse TLR pathways to activate pro-inflammatory signals.
Bundy DL and McKeithan TW (1997) Diverse effects of BCL3 phosphorylation on its modulation of NF-kB p52 homodimer binding to DNA. Journal of Biological Chemistry 272 33132-33139
Bundy RE, Hoare GS, Kite A, Beach J, Yacoub M and Marczin N (2005) Redox regulation of p38 MAPK activation and expression of ICAM-1 and heme oxygenase-1 in human alveolar epithelial (A549) cells. Antioxid Redox Signal 7 14-24
Bunn Jr PA and Foss FM (1996) T-cell lymphoma cell lines (HUT102 and HUT78) established at the National Cancer Institute: history and importance to understanding the biology, clinical features, and therapy of cutaneous T-cell lymphomas (CTCL) and adult T-cell leukemia-lymphomas (ATLL). Journal of Cellular Biochemistry Supplement 24 12-23
Bunnell SC (2002) Determining the destiny of NF-kB after TCR ligation: it’sCARMA1. Molecular Intervention 2 356-360
Bunting K, Rao S, Hardy K, Woltring D, Denyer GS, Wang J, Gerondakis S and Shannon MF (2007) Genome-wide analysis of gene expression in T cells to identify targets of the NF-kB transcription factor c-Rel. Journal of Immunology 178 7097-7109
Buommino E, Schiraldi C, Baroni A, Paoletti I, Lambertia M, De Rosa M and Tufano MA (2005) Ectoine from halophilic microorganisms induces the expression of hsp70 and hsp70B’ in human keratinocytes modulating the proinflammatory response. Cell Stress Chaperones 10 197-203
Burdelya LG, Krivokrysenko VI, Tallant TC, Strom E, Gleiberman AS, Gupta D, Kurnasov OV, Fort FL, Osterman AL, Didonato JA, Feinstein E and Gudkov AV (2008) An agonist of Toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 320 226-230
Burdo TH, Nonnemacher M, Irish BP, Choi CH, Krebs FC, Gartner S and Wigdahl B (2004) High-affinity interaction between HIV-1 Vpr and specific sequences that span the C/EBP and adjacent NF-kB sites within the HIV-1 LTR correlate with HIV-1-associated dementia. DNA Cell Biology 23 261-269
Bureau F, Bonizzi G, Kirschvink N, Delhalle S, Desmecht D, Merville MP, Bours V and Lekeux P (2000) Correlation between Nuclear Factor-kB activity in bronchial brushing samples and lung dysfunction in an animal model of asthma. American Journal of Respir Crit Care Med 161 1314-1321
Bureau F, Desmet C, Melotte D, Jaspar F, Volanti C, Vanderplasschen A, Pastoret PP, Piette J and Lekeux P (2002) A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-kB inhibition. Journal of Immunology 168 5318-5325
Bureau F, Vanderplasschen A, Jaspar F, Minner F, Pastoret PP, Merville MP, Bours V and Lekeux P (2002) Constitutive nuclear factor-kB activity preserves homeostasis of quiescent mature lymphocytes and granulocytes by controlling the expression of distinct Bcl-2 family proteins. Blood 99 3683-3691
Burgermeister E, Endl J and Scheuer WV (2003) Activation of cytosolic phospholipase A(2) in human T-lymphocytes involves inhibitor-kB and mitogen-activated protein kinases. European Journal of Pharmacology 466 169-180
Burgermeister E, Pessara U, Tibes U, Kuster A, Heinrich PC and Scheuer WV (2000) Inhibition of cytosolic phospholipase A(2) attenuates activation of mitogen-activated protein kinases in human monocytic cells. European Journal of Pharmacology 388 195-208
Burgermeister E, Tibes U, Stockinger H and Scheuer WV (1999) Activation of Nuclear Factor-kB by lipopolysaccharide in mononuclear leukocytes is prevented by inhibitors of cytosolic phospholipase A2. European Journal of Pharmacology 369 373-386
Burgess-Beusse Bl and Darlington GJ (1998) C/EBPa is critical for the neonatal acute-phase response to inflammation. Molecular and Cellular Biology 18 7269-7277
Burgos P, Metz C, Bull P, Pincheira R, Massardo L, Errazuriz C, Bono MR, Jacobelli S and Gonzalez A (2000) Increased expression of c-rel, from the NF-kB/Rel family, in T cells from patients with systemic lupus erythematosus. Journal of Rheumatology 27 116-127
Burke JR and Strnad J (2002) The catalytic subunits of IkB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers. Biochemical and Biophysical Research Communications 293 1508-1513
Burke JR (2003) Targeting IkB kinase for the treatment of inflammatory and other disorders. Current Opinion in Drug Discovery and Development 6 720-728
Burke MA and Bothwell M (2003) p75 Neurotrophin receptor mediates neurotrophin activation of NF-kB and induction of iNOS expression in P19 neurons. Journal of Neurobiology 55 191-203
Burkhart BA, Hebbar PB, Trotter KW and Archer TK (2005) Chromatin-dependent E1A activity modulates NF-kB RelA-mediated repression of glucocorticoid receptor-dependent transcription. Journal of Biological Chemistry 280 6349-6358
Burkly L, Hession C, Ogata L, Reilly C, Marconi LA, Olson D, Tizard T, Cate R and Lo D (1995) Expression of relB is required for the development of thymic medulla and dendritic cells. Nature 373 531-536
Burley SK (1995) Rel revealed: cocrystal structures of the NF-kB p50 homodimer. Chemistry & Biology 2 77-81
Buron N, Guery L, Creuzot-Garcher C, Lafontaine PO, Bron A, Rio MC and Solary E (2008) The trefoil factor TFF1 protects conjunctival cells from apoptosis at pre and post-mitochondrial levels. Invest Ophthalmol Vis Sci in press
Burns K, Janssens S, Brissoni B, Olivos N, Beyaert R, Tschopp J (2003) Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. Journal of Experimental Medicine 197 263-268
Burns KA and Martinon F (2004) Inflammatory diseases: is ubiquitinated NEMO at the hub? Current Biology 14 R1040-R1042
Burns LJ, Pooley JC, Walsh DJ, Vercellotti GM, Weber ML and Kovacs A (1999) Intercellular adhesion molecule-1 expression in endothelial cells is activated by cytomegalovirus immediate early proteins. Transplantation 67 137-144
Burstein E and Duckett CS (2003) Dying for NF-B? Control of cell death by transcriptional regulation of the apoptotic machinery. Current Opinions in Cell Biology 15 732-737
Burstein E, Hoberg JE, Wilkinson AS, Rumble JM, Csomos RA, Komarck CM, Maine GN, Wilkinson JC, Mayo MW and Duckett CS (2005) COMMD proteins: A novel family of structural and functional homologs of MURR1. Journal of Biological Chemistry 280 22222-22232
Burysek L, Yeow WS and Pitha PM (1999) Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2). Journal of Human Virology 2 19-32
Busam K, Gieringer C, Freudenberg M and Hohmann H-P (1992) Staphylococcus aureusand derived exotoxins induce NF-kB-like activity in murine bone marrow macrophages. Infection & Immunity 60 2008-2015
Busch LK and Bishop GA (1999) The EBV transforming protein, latent membrane protein 1, mimics and cooperates with CD40 signaling in B lymphocytes. Journal of Immunology 162 2555-2561
Busconi L, Bauer JW, Tumang JR, Laws A, Perkins-Mesires K, Tabor AS, Lau C, Corley RB, Rothstein TL, Lund FE, Behrens TW and Marshak-Rothstein A (2007) Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9. Journal of Immunology 179 7397-7405
Bush AL and Hyson RL (2008) Effects of lithium and deafferentation on expression of glycogen synthase kinase-3beta, NFkB, beta-catenin and pCREB in the chick cochlear nucleus. Brain Research in press
Bush JA, Cheung KJ Jr and Li G (2001) Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53. Experimental Cell Research 271 305-314
Bush KT and Nigam SK (1999) Less degradation, more shock, please. Gastroenterology 116 994-995
Bushdid PB, Brantley DM, Yull FE, Blaeuer GL, Hoffman LH, Niswander L and Kerr LD (1998) Inhibition of NF-kB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis. Nature 392 615-618
Bushdid PB, Chen CL, Brantley DM, Yull F, Raghow R, Kerr LD and Barnett JV (2001) NF-kB mediates FGF signal regulation of msx-1 expression. Developmental Biology 237 107-115
Busquets S, Fuster G, Ametller E, Olivan M, Fiueras M, Costelli P, Carbo N, Argiles JM and Lopez-Soriano FJ (2007) Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models. Clinical Nutrition in press
Buss H, Dorrie A, Schmitz ML, Frank R, Livingstone M, Resch K and Kracht M (2004) Phosphorylation of serine 468 by GSK-3b negatively regulates basal p65 NF-kB activity. Journal of Biological Chemistry 279 49571-49574
Buss H, Dorrie A, Schmitz ML, Hoffmann E, Resch K and Kracht M (2004) Constitutive and IL-1-inducible phosphorylation of p65 NF-kB at serine 536 is mediated by multiple protein kinases including IKKa , IKKb , IKKe, TBK1 and an unknown kinase and couples p65 to TAFII31-mediated IL-8 transcription. Journal of Biological Chemistry 279 55633-55643
Busschots AM, Mecucci C, Stul M, Vandenberghie E, Michaux J-L, Noel H, Cassiman J-J and Berghie HVD (1991) Translocation (14;19)(q32;q13.1) in young patient who developed a large cell lymphoma after initial diagnosis of CLL. Leukemia & Lymphoma 5 281-286
Busse MS, Arnold CP, Towb P, Katrivesis and Wasserman SA (2007) A kB sequence code for pathway-specific innate immune responses. EMBO Journal in press
Bussell K (2001) Staying alive. Nature Reveiws Molecular and Cellular Biology 2 875
Busserolles J, Paya M, D’Auria MV, Gomez-Paloma L and Alcaraz MJ (2005) Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M. Biochemical Pharmacology 69 1433-1440
Bustamante J, Boisson-Dupuis S, Jounguy E, Picard C, Puel A, Abel L and Casanova JL (2007) Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases. Current Opinions in Immunology in press
Bustos C, Hernandez-Presa MA, Ortego M, Tunon J, Ortega L, Perez F, Diaz C, Hernanadez G and Egido J (1998) HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis. Journal of the American College of Cardiology 32 2057-2064
Busuttil V, Bottero V, Frelin C, Imbert V, Ricci J-E, Auberger P and Peyron J-F (2002) Blocking NF-kB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic factor. Oncogene 21 3213-3224
Butchar JP, Rajaram MV, Ganesan LP, Parsa KV, CLay CD, Schlesinger LS and Tridandapani S (2007) Francisella tularensis induces IL-23 production in human monocytes. Journal of Immunology 178 4445-4454
Butcher BA and Denkers EY (2002) Mechanism of entry determines the ability of Toxoplasma gondii to inhibit macrophage proinflammatory cytokine production. Infection and Immunity 70 5216-5224
Butcher HL, Kennette WA, Collins O, Zalups RK and Koropatnick J (2004) Metallothionein mediates the level and activity of nuclear factor kB (NF-kB) in murine fibroblasts. J Pharmacol Exp Ther 310 589-598
Buteau J, El-Assaad W, Rhodes CJ, Rosenberg L, Joly E and Prentki M (2004) Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia 47 806-815
Butler M, Moynagh P and O’Connor J (2002) Methods of detection of the transcription factor NF-kB in rat hippocampal slices. Journal of Neuroscience Methods 119 185-190
Butler MW, Robertson I, Greene CM, O’Neill SJ, Taggart CC and McElvaney NG (2006) Elafin prevents lipopolysaccharide-induced AP-1 and NF-kB activation via an effect on the ubiquitin-proteasome pathway. Journal of Biological Chemistry 281 34730-34735
Butow RA and Avadhani NG (2004) Mitochondrial signaling; the retrograde response. Molecular Cell 14 1-15
Butscher WG, Powers C, Olive M, Vinson C and Gardner K (1998) Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2. Journal of Biological Chemisry 273 552-560
Butt C, Sun S, Peddle L, Greenwood C, Hamilton S, Gladman D and Rahman P (2005) Association of nuclear factor-kB in psoriatic arthritis. Journal of Rheumatology 32 1742-1744
Buzzelli MD, Navaratnarajah M, Ahmed T, Nagarajan M, Shumate ML, Lang CH and Cooney RN (2008) Nuclear factor kB mediates the inhibitory effects of interleukin-1 on growth hormone-inducible gene expression. Journal of Trauma 64 1427-1435
Byeon SE, Lee YG, Kim JC, Han JG, Lee HY and Cho JY (2008) Hinokitiol, a natural tropolone derivative, inhibits TNF-a production in LPS-activated macrophages via suppression of NF-kB. Planta Medica in press
Bylund J, Macdonald KL, Brown KL, Mydel P, Collins LV, Hancock RE and Speert DP (2007) Enhanced inflammatory responses of chronic granulomatous disease leukocytes involve ROS-independent activation of NF-kB. European Journal ofImmunology in press
Byrd CA, Bornmann W, Erdjument-Bromage H, Tempst P, Pavletich N, Rosen N, Nathan CF and Ding A (1999) Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide. Proceedings of the National Academy of Sciences USA 96 5645-5650
Byrd VM, Ballard DW, Miller GG and Thomas JW (1999) Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kB in FGF receptor-bearing Jurkat T cells. Journal of Immunology 162 5853-5859
Byrd-Leifer CA, Block EF, Takeda K, Akira S and Ding A (2001) The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol. European Journal of Immunology 31 2448-2457
Byrne CD (1999) Triglyceride-rich lipoproteins: are links with atherosclerosis mediated by a procoagulant and proinflammatory phenotype? Atherosclerosis 145 1-15
Byrne M, Abdel-Laetif M, Murphy A, Byrne P, Kennedy J, Stepens RB and Reynolds JV (2006) Lymphocyte NF-kB activation after major surgery: Differential response following oesophageal surgery. Journal of Clinical Gastroenterology 40 4 S165
Byun CH, Koh JM, Kim DK, Park SI, Lee KU and Kim GS (2005) alpha-lipoic acid inhibits TNF-a-induced apoptosis in human bone marrow stromal cells. J Bone and Mineral Research 20 1125-1135
Byun HS, Park KA, Won M, Yang KJ, Shin S, Piao L, Kwak JY, Lee ZW, Park J, Seok JH, Liu ZG and Hur GM (2006) Phorbol 12-myristate 13-acetate protects against TNF-induced necrotic cell death by modulating the recruitment of TRADD and RIP into the TNF receptor 1 signaling complex: implication for the regulatory role of PKC. Molecular Pharmacology 70 1099-1108
Byun MS, Choi J and Jue DM (2006) Cysteine-179 of IkB kinase beta plays a critical role in enyzme activation by promoting phosphorylation of activation loop serines. Experimental and Molecular Medicine 38 546-552