The department of Periodontology provides research opportunities to students who are enrolled in the Periodontology Certificate Program interfaced with either the Master of Science in Dentistry (MSD) and/or the Doctor of Science in Dentistry (DScD) in periodontology degrees. The MSD and DScD research endeavors involve patient based as well as clinically related basic science investigations. The research laboratory utilizes multidisciplinary approaches and state-of-the-art technologies combined with 2D and 3D cell, tissue and organ culture models including in vivo animal models to develop fundamental understanding of the principles of biological transformation in human health to disease state(s). Currently, the laboratory has several ongoing projects related to periodontology and craniofacial bone deficiencies. Studies are also pursued in the areas of periodontal/implant surgeries, bone augmentation/regeneration by tissue/biomaterial engineering, and orthodontic tooth movement using 2D cell cultures, live ex-vivo bone organ culture model systems and in vivo animal studies, in conjunction with the use of the piezoelectric knife.
2013-2018 Student Publications (MSc.D & DSc.D)
The involvement of Kav001 in inhibition of LPS/P. gingivalis-induced.
Tang X, Alasiri M, Bamashmous A, Aljahdali B, Cao F, Dibart S, Salih E. J Cell Biochem. 2018 Jul;119(7):6072-6079. doi: 10.1002/jcb.26805. Epub 2018 Apr 10. PMID: 29637600
A method for high transfection efficiency in THP-1 suspension cells without PMA treatment.
Tang X, Aljahdali B, Alasiri M, Bamashmous A, Cao F, Dibart S, Salih E. Anal Biochem. 2018 Mar 1;544:93-97. doi: 10.1016/j.ab.2017.12.032. Epub 2018 Jan 2. PMID:29305095
Bone microenvironment-mediated resistance of cancer cells to bisphosphonates and impact on bone osteocytes/stem cells.
Alasmari A, Lin SC, Dibart S, Salih E. Clin Exp Metastasis. 2016 Aug;33(6):563-88. doi: 10.1007/s10585-016-9798-6. Epub 2016 May 7. PMID:27155840
Effect of Corticotomies with Different Instruments on Cranial Bone Biology Using an Ex Vivo Calvarial Bone Organ Culture Model System.
Dibart S, Alasmari A, Zanni O, Salih E. Int J Periodontics Restorative Dent. 2016;36 Suppl:s123-36. doi: 10.11607/prd.2701.
Quantitative gingival crevicular fluid proteome in health and periodontal disease using stable isotope chemistries and mass spectrometry.
Carneiro LG, Nouh H, Salih E. J Clin Periodontol. 2014 Aug;41(8):733-47. doi: 10.1111/jcpe.12262. Epub 2014 Jun 6. PMID:24738839
Novel bioactivity of phosvitin in connective tissue and bone organogenesis revealed by live calvarial bone organ culture models.
Liu J, Czernick D, Lin SC, Alasmari A, Serge D, Salih E. Dev Biol. 2013 Sep 1;381(1):256-75. doi: 10.1016/j.ydbio.2013.06.005. Epub 2013 Jun 18. PMID:23791550
Topographical distribution of phosphorylation sites of phosvitins by mass spectrometry.
Czernick D, Liu J, Serge D, Salih E. J Proteomics. 2013 May 27;83:76-98. doi: 10.1016/j.jprot.2013.02.016. Epub 2013 Mar 6. PMID:23474079