Meera Kumanan (Class of ’20)

Structural basis for lipid binding and function by an evolutionarily conserved protein, Serum Amyloid A Serum amyloid A (SAA) is a plasma protein that transports lipids during inflammation. To explore SAA solution conformations and lipid-binding mechanism, we used hydrogen-deuterium exchange mass spectrometry, lipoprotein reconstitution, amino acid sequence analysis, and molecular dynamics simulations. Solution conformations of […]