Diphtheria Toxin

Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Diphtheria toxin is produced by corynebacterium diphtheriae, a noncapsulated gram (+) bacillus.  The toxin causes diphtheria complications in humans and can be lethal.  In the laboratory, the toxin release results from lysis of bacillus by a specific virus (bacteriophage).  It is a polypeptide with 2 subunits […]

ROHP Job Risk Assessment

Employees should complete questionnaires and upload immunization documents through their Occupational Health Connect Portal (preferred). If you do not see the questionnaires in your portal, please contact ROHP. If you are a new hire or student, or an employee who does not see the questionnaires in your portal, you may complete through the web using the form below. ROHP is […]

Eastern Equine Encephalitis Agent Information Sheet

Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Eastern Equine Encephalitis (EEEV) is an alphavirus in the family Togaviridae. They are small, enveloped virus with a genome consisting of a single strand of positive sense RNA. Disease/Infection Eastern Equine Encephalitis virus Pathogenicity Alphaviruses may be present in blood, CSF, other tissues (e.g., brain), or […]

ROHP Requirements for Medical Clearance

Who Requires Medical Clearance for Research? Researchers working in a lab or clinical setting NOT listed on an IBC or IACUC protocol do not require medical clearance by ROHP. Researchers working with animals who are receiving any biologics or rDNA in the animal facility or handling ANY hazardous material (that require BSL2 or higher containment, […]

Prions Agent Information Sheet

Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Agent Prion diseases are a variety of neurodegenerative diseases which affect humans, as well as both domestic and wild animal species.  In prion diseases, a cellular prion protein (PrPc) normally found in humans is transformed into a pathogenic isoform (PrPSc) upon exposure to a misfolded prion […]

Powassan virus Agent Information Sheet

Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent A member of the genus Flavivirus, and Flaviviridae family, is an enveloped single stranded RNA virus with two distinct lineages of similar pathogenicity. Powassan Virus is related to other Tick-Borne Encephalitis viruses and may have a similar clinical manifestation to these viruses as well as to […]

Japanese Encephalitis Virus Agent Information Sheet

Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Japanese encephalitis virus (JEV) is a single stranded, enveloped RNA virus which is about 40-50 nm in diameter, and belongs to the Flaviviridae family.   Also referred to as JE, JEV, Japanese B Encephalitis, Arbovirus B, and Mosquito-borne encephalitis virus. Disease/Infection Japanese encephalitis may present as […]

Information For...

Back to Top