Burkholderia cepacia Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Burkholderia cepacia are aerobic rod-shaped, free-living, motile Gram- negative bacteria ranging from 1.6- 3.2 μm. They have been found to possess multitrichous polar flagella as well as pili used for attachment. Burkholderia cepacia can be found in soil, water, and infected plants, animals, and humans. B. […]
Chlamydia trachomatis Agent Information Sheet
Research Occupational Health Program (ROHP) Boston University 617-358-7647 Agent Chlamydiae are small obligate intracellular parasites and were once considered to be viruses. However, they contain DNA, RNA and ribosomes and make their own proteins and nucleic acids and are now considered to be true bacteria. They possess an inner and outer membrane similar gram-negative bacteria […]
Cowpox Brighton virus Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Cowpox Brighton virus was the first virus to be used as a vaccine against smallpox. It is an orthopoxvirus related to smallpox and vaccinia. Disease/Infection Cowpox Brighton virus is the causative agent of bovine vaccinia. It causes rare occupational infections in humans and outside laboratory settings […]
Enterohemorrhagic or Shiga-toxin E. coli
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent E. coli O157:H7 Gram negative rod; motile, aerobic; 63% produce Vero/Shiga toxins (VT/STx), 2 types, VT1/Stx1 and VT2/Stx2 (STEC); serotyping to determine somatic and flagellar antigens Disease/Infection Hemorrhagic colitis, hemolytic uremic syndrome Pathogenicity Can cause moderate to severe infection marked by hemorrhagic colitis, which can lead […]
Haemophilus influenzae Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Haemophilus influenzae is an anaerobic, Gram negative coccobacillus that is non-motile and non-acid-fast. It is a respiratory tract membrane obligate parasite that requires hemin and NAD for in vitro growth. H .influenzae is classified into six antigenically distinct serotypes (a to f) based on capsular polysaccharide antigen. […]
Herpes B Virus Non-human primates Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent The primary infectious agent from non-human primates is Herpes B virus, or Cercopithecine herpesvirus 1 (CHV-1). CHV-1 belongs to the subfamily Alphaherpesvirinae, genus Simplex virus, and is closely related to herpes simplex virus-1 and -2. CHV-1 is the only non-human primate herpesvirus that has been shown […]
KPC Klebsiella Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Klebsiella spp. are Gram-negative, nonmotile, usually encapsulated rod-shaped bacteria, belonging to the family Enterobacteriaceae. Members of the Enterobacteriaceae family are generally facultatively anaerobic, and the genus consists of 77 capsular antigens (K antigens), leading to different serogroups. Specifically, KPC Klebsiella produce carbapenemase, which allows the bacteria […]
La Crosse encephalitis virus (LACV, LAC) Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent La Crosse encephalitis is a rare disease that is caused by a virus spread by infected mosquitoes and contaminated lab water. La Crosse (LAC) encephalitis virus (LACV) is one of a group of mosquito-transmitted viruses that can cause inflammation of the brain (encephalitis). La Crosse virus […]
Measles Agent Information Sheet
Boston University Research Occupational Health Program (ROHP) 617-358-7647 Agent Measles virus is a negative-sense, single stranded RNA virus, which belongs to morbillivirus genus in the Paramyxoviridae family. It consists of a helical nucleocapsid, 100-300 nm in diameter, surrounded by an envelope. The envelope is lined by matrix proteins and carries transmembrane hemagglutinin and fusion glycoproteins […]
MRSA Agent Information Sheet
Research Occupational Health Program (ROHP) Boston University 617-358-7647 Agent Staphylococcus aureus belongs to the family Staphylococcaceae. It is a facultatively anaerobic, nonmotile, gram positive cocci bacteria that forms irregular clusters. Methicillin-resistant Staphylococcus Aureus (MRSA) is a type of staph bacteria that is resistant to certain antibiotics called beta-lactams. These antibiotics include methicillin and other more […]