Professor Chair

Research Interests:

Biological Physics

My group combines femtosecond lasers with nanoparticle systems to enhance electromagnetic fields in time and space  for studying biological systems, and  Quantum non-linear vibrational spectroscopy, and mid-infrared photo thermal spectroscopy. Nonlinear Physics  is exploited to generate exquisitely controlled nanoscale shockwaves that remarkably can inactivate viruses and pathogens without causing collateral damage. Our approach is inherently interdisciplinary spanning Physics, Chemistry, Engineering and Biomedical Science.

Selected Publications:

“Label-free imaging of fibroblast membrane interfaces and protein signatures with vibrational infrared photothermal and phase signals..” Samolis, P. D., Langley, D., O’Reilly, B. M., Oo, Z., Hilzenrat, G., Erramilli, S., . . . Sander, M. Y. (2021).  Biomed Opt Express, 12(1), 303-319. doi:10.1364/BOE.411888

“Anomalous pH-Dependent Enhancement of p-Methyl Benzoic Acid Sum-Frequency Intensities: Cooperative Surface Adsorption Effects”Andino, R. S., Liu, J., Miller, C. M., Chen, X., Devlin, S. W., Hong, M. K., . . . Ziegler, L. D. (2020). .. J Phys Chem A, 124(16), 3064-3076. doi:10.1021/acs.jpca.9b10809

“Femtosecond photonic viral inactivation probed using solid-state nanopores” Nazari, M. et al (2018).  Nano Futures, 2(4), 045005. doi:10.1088/2399-1984/aadf9d

“Ultrafast Two-Dimensional Infrared Spectroscopy of a Quasifree Rotor: J Scrambling and Perfectly Anticorrelated Cross Peaks” Greg Ng Pack, Parth P. Shah, Shyamsunder Erramilli, and L. D. Ziegler  Phys. Rev. Lett.120, 103401 (2018).

Wireless actuation of bulk acoustic modes in micromechanical resonators”, F. Mateen, B. Brown, S. Erramilli and P. Mohanty, “Applied Physics Letters 109, 073502 (2016).

“Multispectral Cesaro-Type Fractal Plasmonic Nanoantennas”, Ekin Aslan, Erdem Aslan, Ren Wang, Mi K. Hong, Shyamsunder Erramilli, Mustafa Turkmen, Omer G. Saracoglu, and Luca Dal Negro, ACS Photonics 3, 2102-2111 (2016).

“Pitchfork Bifurcation and Zharov splitting in Nonlinear Mid-infrared Photothermal Spectroscopy”, A. Mertiri, H. Altug, M. K. Hong, P. Mehta, J. Mertz, L.D. Ziegler and S. Erramilli (2014) ACS Photonics 1, 696-702.

“Dispersed Three-Pulse Infrared Photon Echoes of Nitrous Oxide in Water and Octanol”, J. T. Shattuck, J. R Schneck, L. R. Chieffo, S. Erramilli, L. D. Ziegler (2013) Journal of Physical Chemistry B, 117: 15774-15785.

“Infrared Images in liquid water obtained using a Scanning Near Field Infrared Microscope based on a Free Electron Laser”, M. K. Hong, N. Dokholyan, A. Jeung, T. I. Smith, H. A. Schwettman, P. Huie, Shyamsunder Erramilli, (1998), Nucl. Inst. Methods. Phys. Res. Sect. B 144, 246-255.

For a full list of publications, please see the attached CV.


  • duPont Young Professor Award (1996)

Professor in Biomedical Engineering (Joint), Boston University