Neurophotonics NRT Seminar: Mark Howe
MARK HOWE, PhD
Assistant Professor, Psychological & Brain Sciences
Boston University
“Large-Scale Optical Fiber Arrays for Measuring Striatum-Wide Signals During Learning and Action”
Wednesday, March 31, 12-1pm (ET)
This seminar is open to the BU community. Registration is required. Please use your BU email address to register.
Register Here
ABSTRACT
The striatum is a large, deep-brain structure implicated in diverse functions including movement invigoration, action selection, and learning. Evidence from anatomical, behavioral, and physiological studies has indicated that different striatum sub-regions support distinct aspects of behavior. I will describe a new optical fiber approach we have developed in mice to investigate how the activity patterns of neurotransmitter release, local interneurons, and cell-type specific projection neurons evolve across the entire striatum over different spatial and temporal scales to support adaptive action and learning. This approach can be flexibly applied to investigate widely distributed neural dynamics within and across brain regions occupying large, deep brain volumes.