Posted October 25, 2022

Post-doctoral research associate position at the Boston University National Emerging Infectious Diseases Laboratories (NEIDL) to work on human responses to Nipah virus infection.

Summary: The laboratories of Dr. Mühlberger, Crossland and Douam at the Boston University National Emerging Infectious Diseases Laboratories (NEIDL) are seeking to recruit a post-doctoral research associate to conduct a 3-year funded project focusing on characterizing the human responses to Nipah virus (NiV) infection. This multidisciplinary and highly collaborative project aims to identify human signatures driving NiV pathogenesis using advanced cell-based systems (induced-pluripotent stem cell-derived cells or iPSC) and humanized mouse models and harness those signatures to identify drug targets for the treatment of NiV infection.

What we offer: The successful applicant will work in a state-of-the-art biosafety level 4 laboratory (BSL-4) and will have the opportunity to spearhead a project at the interface of molecular and cellular virology (Mühlberger lab), mouse models of viral infection (Douam Lab), and imaging-based characterization of viral pathogenesis (Crossland Lab). The applicant will also closely collaborate with the Boston University Center for Regenerative Medicine (Kotton and Mostoslavsky labs; iPSC component of the project) and the University of Florida (Wuchty lab, University of Florida; System biology component of the project). In addition to building a unique set of skills, the successful applicant will also benefit from the unique resources available at the NEIDL and on the Boston University Medical Campus (BUMC) for professional development. The Mühlberger, Crossland and Douam Lab includes a large group of diverse and passionate staff scientists, graduate students and post-doctoral research associates who foster an inclusive and safe work environment.

What we are looking for: We are looking for a motivated and team-oriented scientist with a Ph.D. in molecular or cellular virology and a strong interest in emerging infectious diseases and host-pathogen interactions. We seek a science-driven individual willing to expand their skill sets and research interests and enjoy working in a highly collaborative and interactive environment. The successful applicant will lead the production of research manuscripts and present their data at international scientific conferences. While previous experience in molecular and cellular virology is required, experience with mouse work and/or biocontainment work is preferred but does not constitute a requirement for this position. Excellent verbal and written communication skills, as well as organization skills, are required.

About the Boston University National Emerging Infectious Diseases Laboratories (NEIDL): The NEIDL is a national resource and seven-story facility housing BSL-4 and BSL-3 biocontainment laboratories and vivaria as BSL-2 laboratories. Located on the BUMC, the NEIDL provides comprehensive core research facilities that enable basic, translational and clinical research at biosafety levels 2, 3 and 4. This includes developing and/or evaluating therapies and vaccines related to emerging zoonotic infectious diseases and the biodefense research agenda.  Numerous core facilities within and outside the NEIDL enable a comprehensive array of research methodologies and services amenable to biocontainment research, such as high-resolution flow cytometry, single-cell transcriptomics, human organoid generation, animal care support, and advanced imaging and histopathology analyses. The NEIDL is centered around a unique scientific environment built around the Boston University School of Medicine and Public Health and the Boston Medical Center, the principal teaching hospital for the medical school. The NEIDL also benefits from its geographical and intellectual proximity to many other biomedical research institutes in the Boston area.

How to apply: Interested candidates are invited to send a cover letter and C.V. to Dr. Mühlberger (muehlber@bu.edu), Crossland (ncrossla@bu.edu) and Douam (fdouam@bu.edu).