Catalog of mitochondria across life’s family tree unearths new roles for the cell’s powerhouse
The MitoCarta Tree of Life consortium, or MitoTOL, generated and analyzed the mitochondrial proteomes of one plant and five single-celled pathogens that affect millions of people globally every year. Their results reveal unexpected new functions of the organelle, clues to its origin and role in the evolution of complex-celled organisms known as eukaryotes, and potential new drug targets for neglected tropical diseases.