Biomedicine
Advancing COVID-19 Drug Development via Network Analysis
CISE Faculty Affiliate Mark Crovella (Prof., CS, Bioinformatics) has teamed up with Simon Kasif (Prof., BME, CS, Bioinformatics) and other CS researchers from across the U.S. to advance COVID-19 drug development via Network Analysis. The researchers are co-developing a machine learning methodology to analyze viral and human protein-protein interaction networks. Through this work, the researchers […]
SemiSynBio-II: Hybrid Bio-Electronic Microfluidic Memory Arrays for Large Scale Testing and Remote Deployment
The ability to record events (“memory”) is a crucial part of many complex systems. Recording events allows these systems to modify their behavior based on previous interactions, report on their history, or communicate local information to a global community. Biological systems will benefit greatly from the creation of memory elements. Biological memories in bacterial or […]
A Soft Robotic Sleeve to Enable Safer and Easier Colonoscopy Procedures
Current flexible endoscopes have limited dexterity and sensor feedback, making navigation in colonoscopy a challenging task. These technical limitations make screening procedures poorly tolerated by patients, leading to low rates of compliance with screening guidelines and/or incomplete colonoscopy, that is associated with higher rates of interval proximal colon cancer. Alternative engineering solutions have been proposed […]
A Soft Robotic Sleeve to Enable Safer and Easier Colonoscopy Procedures
Current flexible endoscopes have limited dexterity and sensor feedback, making navigation in colonoscopy a challenging task. These technical limitations make screening procedures poorly tolerated by patients, leading to low rates of compliance with screening guidelines and/or incomplete colonoscopy, that is associated with higher rates of interval proximal colon cancer. Alternative engineering solutions have been proposed […]
ENG Interdisciplinary Team Wins NSF Grant to Create Smart Biosensors
Professors Douglas Densmore (ECE) and Rabia Yazicigil (ECE, CISE faculty affiliate) were awarded a $1.5M grant by the National Science Foundation for project entitled “SemiSynBio-II: Hybrid Bio-Electronic Microfluidic Memory Arrays for Large Scale Testing and Remote Deployment.” Professor Ahmad (Mo) Khalil and Professor Wilson Wong of BME are also Co-PIs on the grant. The award is for a three-year project aiming […]
GCR: Collaborative Research: Fine-grain generation of multiscale patterns in programmable organoids using microrobots
People with diseased or defective vital organs often need organ replacement to survive, but the availability of replacement organs is severely restricted by shortages of suitable tissue-matched donors and complexities such as postmortem organ deterioration and immunological rejection. These problems could be overcome by using high fidelity artificially-grown organs, but achieving that goal faces daunting […]
BU-Harvard Team Wins $1.2M NSF Grant to Improve Women’s Reproductive Health using AI and Machine Learning
A multidisciplinary team of researchers from Boston University and Harvard University is working to address women’s reproductive health challenges with the help of a $1.2M, four-year grant funded by the National Science Foundation (NSF) through its Smart and Connected Health (SCH) program. The BU-led project will leverage machine learning and artificial intelligence to develop an […]
Optimizing and Learning Strategies for Protein Docking
Protein docking is defined as predicting the three-dimensional structure of the docked complex based on knowledge of the structure of the components. Experimental techniques for this purpose are often expensive, time-consuming, and in some cases, not feasible; hence the need for computational docking methods. The problem of finding the docked conformation is generally formulated as […]
CISE Faculty Affiliate Lei Tian Wins NSF CAREER Award
CISE Faculty Affiliate Professor Lei Tian (ECE, BME) received a prestigious Faculty Early Career Development (CAREER) Program Award from the National Science Foundation (NSF) for his work on Optical Intensity Diffraction Tomography with Multiple Scattering. Professor Tian’s research involves the development of novel optical imaging devices that overcome barriers to studying biological samples and phenomena. This project focuses on […]
CIF: Small: Collaborative Research: Signal Processing for Nonlinear Diffractive Imaging: Acquisition, Reconstruction, and Applications
There is a growing need in biomedical research to observe biological structure and processes on the length scales smaller than 100nm. Conventional optical systems cannot effectively provide such information, however, due to the infamous diffraction limit. The formulation of the diffraction limit fundamentally relies on the presumed linearity in the interaction between the illuminating light […]