Congrats to my Boston University Ph.D. student Ariane Garrett on her Translational Research Award at SPIE PhotonicsWest 2025. This is a very competitive award and she gave a very nice acceptance talk entitled “Speckle contrast optical spectroscopy improves cuffless blood pressure estimation compared to photoplethysmography.” Thanks to the program committee and the Translational Research Chairs, […]
Today we’re sharing our new bioRxiv preprint on cuffless blood pressure measurements using high-speed speckle contrast optical spectroscopy (SCOS). We show that measurements of pulsatile blood flow with SCOS can substantially improve blood pressure estimates above what’s available with photoplethysmography (PPG). We believe this opens the door to continuous ambulatory blood pressure without a cuff, […]
Very happy to announce that today my lab published our first paper in hashtag#SPIE hashtag#BiophotonicsDiscovery. Manuscript here: link My talented student Anahita Pilvar, along with our collaborator Jorge Plutzky at Harvard Med/Brigham and Women’s Hospital, went on a several year journey to try to understand how a specific meal could affect your skin and tissue […]
Darren has been named the new editor-in-chief of SPIE Biophotonics Discovery. The journal will provide an outlet for basic science and applications of emerging and novel biophotonic techniques.
Anahita Pilvar, Jorge Plutzky, Mark C. Pierce, Darren Roblyer, “Shortwave infrared spatial frequency domain imaging for non-invasive measurement of tissue and blood optical properties”, Journal of Biomedical Optics, 27(6), 066003 (2022), link
Ph.D. student Sam Spink was the first author in our new paper which describes the design and performance of a new highly flexible wearable probe that uses near infrared light to probe breast tissue. Sam and the research team explored how paced (slow) breathing can be used to quantify the hemodynamic state of breast tissue, […]
Long time BOTLab member (Raeef was the first employee of the BOTlab in 2012 before becoming a Ph.D. student) successfully defended his Ph.D. His thesis is entitled: “FREQUENCY-DOMAIN DIFFUSE OPTICAL SPECTROSCOPY FOR CARDIOVASCULAR AND RESPIRATORY APPLICATIONS” Congratulations Raeef!!
In this work we used SFDI to monitor optical scattering in prostate and breast animal tumor models. We found that the reduced scattering coefficient was strongly correlated with apoptosis, and the scattering power was strongly correlated with proliferation. This helped us track treatment response to cyclophosphamide and the antiangiogenic DC101. This work helps establish optical […]