TL1: Regenerative Medicine Training Program

Currently on hold. Updates regarding future application cycles will be provided as they become available

The BU CTSI TL1 Predoctoral and Postdoctoral Fellowships in Regenerative Medicine is committed to increasing the research workforce.

Regenerative medicine represents the next evolution of medical treatments through the replacement, engineering, or regeneration of damaged human cells, tissues, or organs to restore normal function. This groundbreaking field of medicine truly encompasses the concept of “bench to bedside” translational and personalized medicine research. Both the BU CTSI and BU School of Medicine place a strong emphasis on regenerative medicine, which also plays a central role in NCATS’ mission of expediting personalized medicine and the discovery and rapid delivery of cell-based therapeutic and pharmacologic approaches to market.

The result of interest sparked by an Affinity Research Collaborative (ARC) on iPSC, the Regenerative Medicine Training Program (RMTP)—BU CTSI’s transformative 2-year TL1 aims to support the creation of a pipeline of well-trained scientists and future leaders in the field of translational research by:

  • Providing an innovative, integrative, and interdisciplinary training program, based on CTSA nationally developed competencies and leveraging the unique and internationally recognized strength of BU;
  • Facilitating translational team science interactions, synergistically bridging research strengths with interdisciplinary approaches;
  • Engaging pre- and post-doctorates who have already excelled and whose research would be transformed with the inclusion of regenerative medicine expertise and resources, making “today’s trainees the teachers of tomorrow;”
  • Offering ongoing career and research guidance by mentors (primary and secondary) who have led successful, cross-disciplinary, sustained teams in groundbreaking areas and participated in the train-the-mentor

    Created in collaboration with the Center for Regenerative Medicine (CReM), with its extensive faculty expertise, vast networking capabilities, and state-of-the-art facilities and resources, the RMTP TL1 provides scientific expertise, laboratory, and financial support to trainees from many different departments and biological disciplines across BU, such as dentistry, medicine, surgery, pediatrics, geriatrics, cardiology, and biomedical engineering

    Integrating CReM as a training facility is a win-win for students and the institution alike. Regenerative medicine has been the most sought after discipline for BU School of Medicine PhD applicants, and the CReM faculty receives the greatest number of requests from matriculating students to conduct their PhD dissertation work. Until the establishment of the RMTP TL1 program, only a limited number of students could be accepted. The program will thus not only increase the capacity of trainees within the CReM but also extend the scope of regenerative medicine research to other disciplines.

    Program Faculty

    TL1 Leadership:

    Darrell Kotton, MD, PI and Program Leader of the RMTP TL1 of the RMTP TL1.  Dr. Kotton joined BU’s faculty in 2004 and is the David C. Seldin Professor of Medicine, Professor of Pathology and Laboratory Medicine, and is the founding Director of the Centerfor Regenerative Medicine (CReM) of Boston University and Boston Medical Center. As an educator, Dr. Kotton has won accolades, such as the BU GMS 2018 Educator of the Year Award and the BU Department of Medicine’s 2014 Robert Dawes Evans Senior Mentoring Award. As an ambassador of the TL1 program nationally, Dr. Kotton also leads our efforts to share the program, its iPS cell and organoid bank, and our training modules across all CTSA sites, as exemplified by our NCATS U01 (PI, Dr. Kotton) supporting national sharing of the iPSC network.

    Chris Chen, MD, PhD, Associate Leader of the TL1 whose role is integration of the School of Engineering within the RMTP. Dr. Chen is Professor of Biomedical Engineering, has served as a TL1 mentor on our RMTP for several years, and has been an instrumental figure in the development of engineered cellular microenvironments to understand how cells build tissues.

    Elke Muhlberger, PhD, Associate Leader of the TL1 whose role is to ensure integration of the RMTP with our National Emerging Infections Diseases Laboratory (NEIDL), BU’s unique BL4 facility focused on injury and repair associated with emerging infectious diseases. Dr. Muhlberger is a veteran mentor of our TL1 program. She has co-mentored trainees studying the biology of pathogens responsible for hemorrhagic fevers and their associated multi-organ responses to injury.

    Matt Jones, PhD, Trainee Advisor of the TL1 whose role is to interact with our valuation group and lead the predoctoral training component of the RMTP. In his role as educator and a leader in graduate student education at BU, Dr. Jones  focus has been on recruiting, mentoring, and retaining students in the TL1 program who are interested in regenerative medicine related aspects of translational research.

    TL1 Trainees
    Post-Doctoral TL1 Trainees
    Trainee Appointment Start Date Appointment End Date
    Ian Kinstlinger 3/31/2021 3/30/2023
    Stephen Moore 3/31/2021 3/30/2023
    Gwen Beacham 6/21/2022 6/20/2024
    Michael McLellan 2/1/2024 1/31/2025
    Charles Kerr 8/1/2024 7/31/2025
    Pre-Doctoral TL1 Trainees
    Trainee Appointment Start Date Appointment End Date
    Elissa Everton 4/15/2020 4/14/2021
    Christine Odom 6/1/2020 5/31/2021
    Taylor Michael Matte 4/15/2020 3/31/2022
    Anna Smith 7/1/2020 6/30/2022
    Keshia Pitt 4/15/2020 1/31/2021
    Alexandra Ysasi 4/15/2020 3/31/2022
    Isabella Claure 9/1/2021 8/31/2023
    Carly Merritt 2/1/2022 1/31/2024
    Liz Flores 1/1/2022 12/31/2023
    Zewde Ingram 7/1/2022 6/30/2024
    Sebastian Naranjo 6/1/2022 5/31/2024
    Kiloni Quiles-Franco 7/1/2022 3/31/2023
    Carly Golden 4/1/2023 3/31/2025
    Erin Hennessey 7/1/2023 6/30/2024
    Delaney Gray 7/1/2023 6/30/2024
    Rose Zhao 4/1/2023 3/31/2025
    Dilnar Mahmut 6/1/2024 5/31/2025
    Lauren Ayers 6/1/2024 5/31/2025
    Master of Science in Biomedical Research

    Master of Science Program in Biomedical Research: An Interdisciplinary Approach to Science

    The Master of Science in Biomedical Research Technologies is a new one-year program designed to prepare future experts with a solid grasp of the principles underlying various research core technologies operations, its relevance to an array of biomedical problems and the technical skills to implement these technologies.

    Visit https://www.bumc.bu.edu/gms/brt/ to learn more.