CReM logo

CENTER
FOR
REGENERATIVE
MEDICINE

The Center for Regenerative Medicine (CReM) is a collaborative effort among scientists at Boston University and the Boston Medical Center that aims to advance stem cell research and regenerative medicine for the sake of patients. The research of the CReM is particularly focused on those suffering from diseases commonly seen at the Boston Medical Center. This research includes a focus on a technology discovered in 2006: induced pluripotent stem (iPS) cells.





iPS Cell Colonies

WHAT
ARE
iPS CELLS ?

Induced pluripotent stem cells are derived from the donated skin or blood cells of adults and, with the reactivation of four genes, are reprogrammed back to an embryonic stem cell-like state. Like embryonic stem cells, iPS cells can be differentiated toward any cell type in the body, but they do not require the use of embryos. Since this discovery four years ago, our knowledge about iPS cells has exponentially expanded.

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Embryonic lung: TTF1-GFP mouse

CReM
IN THE
NEWS

CReM Investigators Publish Differentiation of Stem Cells to Lung Progenitors See the original publication in Cell Stem Cell: Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells. See the article in BU Today!

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CReM researchers Gustavo Mostoslavsky (from right), Darrell Kotton, and George Murphy.