Overview of the laboratory

Our research interests focus on identifying novel genes and pathways that are essential for MYC-driven tumor transformation and progression, particularly for T-cell lymphoblastic lymphoma/leukemia, neuroblastoma, and breast cancer.  The research strategy of our laboratory is to couple the genomic and molecular analyses of human cancer cells with genetic and imaging capacities of the zebrafish system. The long-term goal of the laboratory is to partner with industry and clinicians to translate basic research to the bedside for improved management and treatment of aggressive and metastatic cancers.