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There are 4 comments on SPH Study: Increased Risk of Birth Defects from Opioid Use

  1. Aspirin, ibuprofen and naproxen are generally contraindicated in pregnancy because of their anti-platelet effects and risk for placental abruption. Acetaminophen has recently been tied to higher risk of ADHD in pregnancy exposed children. There are no perfect options. I suspect in this retrospective analysis of opioid exposure in pregnancy that mothers who use narcotic pain medications especially early in pregnancy are also exposed at a higher rate to other medications in pregnancy as well.

    1. There is a second study in which acetaminophen use during pregnancy has been shown to increase the risk of adverse neurodevelopmental outcomes. This study found a 70% increased risk of behavioral and motor problems and double the risk of communication problems in 3 year olds from prolonged use.

  2. (SAR ’87, SAR ’89)
    One problem is that pregnant women can only take acetaminophen. NSAIDs early in pregnancy are okay, but can cause problems later, so we generally tell patients to avoid them throughout. Fioricet is a possibility for headaches (acetaminophen-caffeine-butalbital), but if the patient has other types of pain, it’s very difficult to manage since our arsenal is so restricted. We generally avoid narcotic-containing meds, but sometimes it can’t be helped.

  3. ok Boston Hospital. I know you are an excellent and very intelligent facility but please stop scaring people with this nonsense. All sorts of things cause damage to the fetus. We know this. It is not just Opiates that may cause problems during pregnancy. Many things….even something as simple as diet or smoking may cause a problem Please stop spreading more fear. Chronic pain patients are suffering so needlessly now. Please stop frightening people with your bias and do more research. Maybe you will find a way to help people who are already adults whose mothers did care for their bodies during pregnancy, even when it was difficult, as mine was because of 2 hip replacements. I had a healthy baby. I was able to stop all medications during pregnancy for the sake of my child. I’m sure if you forced too many vitamins on a pregnant woman then she may have a bad pregnancy outcome. It happens. Please help people who are already suffering when they could be helped by opiates. People don’t need these scare tactics that don’t cover all the bases in the “real” world anymore. People need help.

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