Special Bioinformatics Seminar
Special Bioinformatics Seminar
Monday 4/28 @ 5:30 pm LSEB B01 – 24 Cummington Mall
Analytical Challenges in Clinical Cancer Diagnostics by NGS
Doron Lipson, PhD
Senior Director, Computational Biology Methods at Foundation Medicine in Cambridge
Dr. Lipson has over 10 years of experience in developing genomic applications. He is currently leading a team responsible for developing clinical-grade computational methods for detecting driver alterations in tumors from NGS data at Foundation Medicine. Previously, he has worked at Helicos BioSciences and at Agilent, and was a co-founder of ProteOptics, which was acquired by Bio-Rad in 2006. Dr. Lipson received his Ph.D. in Computer Science from Israel Institute of Technology, and his B.S. in Computer Science and Biology from the Hebrew University of Jerusalem.
Recent Publications
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas Nature Communications / 20 January 2014
A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma Clinical Cancer Research / 1 January 2014
BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition Clinical Cancer Research / 15 December 2013
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer Nature Medicine / 27 October 2013
Nature Biotechnology / 20 October 2013
Relapsed classic E-cadherin (CDH1) mutated invasive lobular breast cancer demonstrates a high frequency of HER2 (ERBB2) gene mutations Clinical Cancer Research / 10 April 2013
Host: Simon Kasif