Alex Bloom, Ph.D.

Post-doctoral Scholar

  • Title Post-doctoral Scholar
  • Office 36 Cummington St., Room 307
  • Education B.S. Biochemistry – Brandeis University (2006)

Curriculum Vitae

Research Interests

During cancer cell metastasis from the primary tumor site, the extracellular matrix (ECM) is modified and reorganized by the cancer cells.  My interests lies in understanding specifically how the ECM is modified to promote or allow for metastasis by using three dimensional tissue culture techniques

Selected Publications

Bloom, A. B. & Zaman, M. H. (2014). Influence of the microenvironment on cell fate.  Physiological Genomics, 46, 309-314.

Makkinje, A., Near, R. I., Infusini, G., Vanden Borre, P., Bloom, A., Cai, D., Costello, C., & Lerner, A. (2009). AND-34/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern. Cellular Signalling, 21(9), 1423–1435.

Near, R. I., Smith, R. S., Toselli, P. A., Freddo, T. F., Bloom, A. B., Vanden Borre, P., Seldin, D., & Lerner, A. (2009). Loss of AND-34/BCAR3 expression in mice results in rupture of the adult lens. Molecular Vision, 15, 685–99.

Garron, M. L., Arsenieva, D., Zhong, J., Bloom, A. B., Lerner, A., O’Neill, G. M., & Arold, S. T. (2009). Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance. 

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