CTSA – Ansible, January 2021

THE SPOTLIGHT | WHAT’S NEW | GET INVOLVED | CONSORTIUM CORNER

Mike’s Blog January 2021

Happy New Year!

We have arrived in 2021, hopeful for scientific advances to curb this pandemic once and for all. Our preparedness and readiness have been crucial in the development and implementation of several clinical trials leading the way in identifying safe and effective therapies and diagnostics for COVID-19.

During this process, we have witnessed incredible levels of innovation and adaptation, from the N3C cloud-based data platform to study clinical and other aspects of the pandemic, to developing innovative clinical trials through adaptive designs and master protocols, to supporting research and the development of technologies to follow up research participants remotely, to strategies for enrollment of underrepresented minorities and other populations that have been less representative during the R&D process. (To Access Full Blog – Click Here)

THE SPOTLIGHT

2021 Pod Assignments

CTSA Program Steering Committee (SC) members look forward to meeting with their pods this year! The 2021 Pod assignments have been updated to reflect this year’s rotation of outgoing and incoming SC members. UL1 Pod members are strongly encouraged to include their hub’s KL2 PI, their Administrator and if applicable, their TL1 PI on Pod calls and emails when necessary and relevant. Please visit the CLIC Steering Committee website for the 2021 Pod list and the Steering Committee Roles and Responsibilities document for more information.

WHAT’S NEW

COVID-19 Research Open House Week & Community Research Symposium

N3C is hosting Open House Week: Jan 19th – 25th, 2021 to engage CTSA members, newcomers, and the wider translational research community. The event will be kicked off with a 1-hour symposium, followed by a week of open Clinical Domain Team meetings to welcome new collaborators and help them launch their research questions.

Kick-off Event: Community Research Symposium: Jan 19th, 2021

Agenda:
Opening remarks from N3C leadership
N3C Tutorial: How to Get Involved
PI/Clinician Testimonial: David Ellison, MD/OCTRI
Flash talks from the Pregnancy and Diabetes & Obesity Domain Teams
Demonstration of the N3C Data Enclave

For More Information >

Save the Date Spring CTSA Program Meeting

This virtual meeting will feature the CTSA Program groups discussing their respective accomplishments, future direction and goals.
We plan to incorporate different aspects to enhance your virtual meeting experience, including the following:

Attendee virtual meeting platform training
Downloadable reference materials
Interactive Q & A
1:1 meetings
Breakout space, if necessary
Recorded sessions and slide decks for future access

Registration will open on Tuesday, January 19th.

For More Information >

COVIDome Dataset

The COVIDome Project at the University of Colorado Anschutz Medical Campus is a collaborative multidisciplinary project that aims to accelerate translational research in COVID-19 by generating and integrating matched multi-omics and clinical datasets and making them broadly accessible through an online portal ahead of publication. The dataset currently consists of matched analyses of the transcriptome using RNAseq, plasma proteome using mass spectrometry and SOMAscan technology, deep cytokine profiling, plasma and red blood cell metabolomes, deep immune cell profiling via mass cytometry, seroconversion assays, and clinical data. All data are made available through a user-friendly researcher gateway known as the COVIDome Explorer, which is equipped with online analysis tools for rapid hypothesis testing and hypothesis generation by interested scientists/researchers.

For More Information >

Informatics Community Using EHR Data to Answer COVID-19 Questions: Featuring the Acute Kidney Injury (AKI) & Critical Care/Ventilation/Multi-organ Dysfunction Syndrome (MODS) Domain Teams

New – R03 Program for the NCATS Clinical and Translational Science Award (CTSA) Program

The purpose of the R03 program is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of diversity and re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Application budgets are limited to direct costs up to $50,000 per year for a maximum period of 2 years. First due date is March 26, 2021.

For More Information >

R21 CTSA Collaborative Innovation Awards (PAR-19-100) – Due date approaching

This FOA supports investigators from two or more CTSA Program hub institutions to either: 1) form new collaborations, or to 2) significantly expand the scientific scope of existing collaborations, or to 3) engage new collaborators in pre-existing collaborations to solve a translational science problem no one hub can solve alone, or disseminate a solution to a translational science problem developed at one hub to other hubs, thereby testing its robustness to different hub environments and structures and adapting it for further dissemination within and outside the CTSA Program consortium if appropriate. Maximum project period is 2 years and combined budget for direct costs for the two-year project period may not exceed $275,000. Next due date is March 8, 2021.

For More Information >

U01 CTSA Collaborative Innovation Awards (PAR-19-099) – Due date approaching

This FOA supports investigators from three or more CTSA Program hub institutions to either: 1) form new collaborations, or to 2) significantly expand the scientific scope of existing collaborations, or to 3) engage new collaborators in pre-existing collaborations to solve a translational science problem no one hub can solve alone, or disseminate a solution to a translational science problem developed at one hub to other hubs, thereby testing its robustness to different hub environments and structures and adapting it for further dissemination within and outside the CTSA Program consortium if appropriate. The maximum project period is 4 years. Application budgets are limited to no more than $750,000/year in direct costs excluding consortium/contractual F&A costs. The next due date is March 8, 2021.

For More Information >