We are looking for postdoctoral associates with experience in computational biophysics or structural bioinformatics. Candidates should have a strong background in theoretical physics, applied mathematics, or computer science, demonstrated by outstanding publication record. Our research focuses on molecular recognition, including protein-protein interactions and computer aided drug design. The primary goal of the lab is algorithm […]
Author: Amanda Wakefield
If you are interested in doing graduate work within our center, please apply to the Department of Biomedical Engineering at Boston University or the Department of Chemistry at Boston University. You can contact BMERC beforehand to obtain more information.
The ClusPro protein-protein server is the best performer in the CAPRI46-CASP13 prediction competition
ClusPro is a web server that performs rigid body docking of two proteins by sampling billions of conformations. The server has over 13,000 registered users and performs about 5,000 docking calculations each month. The two papers describing ClusPro have been cited over 1,500 times, and over 600 of these papers reported protein complex models built […]
Dr. Marcelo Castilho, a Professor at the Universidade Federal da Bahia, spent two months working with the Vajda lab during the summer of 2018. The first paper resulting from this collaboration, TQ Froes et al. Structure-based druggability assessment of anti-virulence targets from Pseudomonas Aeruginosa, was published on April 17, 2019, in the journal Current Protein […]
The BMERC has accepted multiple high school students through the BU RISE program. These students work 40 hours a week for six weeks in one or more of our affiliated labs. This experience provides each of the students unparalleled access to both experimental and computational facilities.
Abstract: One of the main area of our research, supported by the MIRA grant R35 GM118078, entitled Analysis and Prediction of Molecular Interactions, is investigating the interactions between proteins and small molecules, including drugs and metabolites. Bioactive small molecules, such as the products of cellular metabolism, natural products and synthetic organic compounds, are potent mediators […]
Speaker: Paul C. D. Hawkins, Ph.D. Head of Scientific Solutions OpenEye Scientific Title: When thinking is just not enough: Computation for drug discovery at 10^0 to 10^10. Abstract: This talk will highlight two applications of computation in modern drug discovery: similarity searching at scales up to and beyond 10^10 and ligand design using a rigorous […]
The recently held BMERC open house featured posters from labs across the Chemistry and Biomedical Engineering departments. The event successfully allowed graduate students and faculty members to engage undergraduate students in conversations about the many research projects going on at BMERC. Many undergraduate students were surprised at the wide variety of labs and their projects […]