Alcohol, Other Drugs, and Health: Current Evidence

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March-April 2026

Interventions and Assessments

  • Dutasteride as a Promising Option to Decrease Heavy Drinking

Health Outcomes

  • High 12-month Adherence to Buprenorphine Associated with Improved Health Outcomes in Youth with Opioid Use Disorder
  • Opioid Overdose Risk Higher for Individuals Who Utilize Varied Routes of Administration
  • Observational Study Finds Association Between Adolescent Use of MDMA and Anxiety in Adulthood
  • Nicotine-containing E-cigarette Cessation Unaffected by Cannabis Co-use Among Youth
  • Weekly Drug Testing is Associated With Modestly Improved Treatment Retention Among People Receiving Medications for Opioid Use Disorder

Prescription Drugs and Pain

  • Abrupt Opioid Medication Dose Reductions Associated With Increased Mental Health and Substance Use-related Emergency Visits, While Modest Dose Reductions Are Not

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