Prereq: Consent of instructor. Successful basic science research in Biochemistry, Cell, and Molecular Biology requires proposing, developing and testing a novel hypothesis. The generation of a novel hypothesis in turn requires the ability to apply the scientific method and then implement the appropriate techniques to address the experimental question. This course will complement the Foundations in Biomedical Sciences (FIBS) curriculum by providing students with a comprehensive understanding of the experimental methods used in Biomedical research. By the end of this course students will master the concepts behind a wide range of experimental techniques and technologies and then be prepared to apply the most appropriate experimental system to a given biological question. Biochemical knowledge regarding "how things work" will enable students to develop their own experimental research strategies. This course will be offered for 1st year PhD students and will use a traditional lecture approach, problem sets, and discussions. Course materials will include classic papers from the literature, laboratory protocols, and problem sets. A comprehensive final written assignment is designed to test the students' mastery of the subject matter. Layne. 2 cr, Fall sem.

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