Welcome to USArhythms (Ultra Slow Arterial rhythms)!

The vasculature of the cerebral cortex orchestrates the allocation of energy resources, oxygen and glucose, throughout cortical areas with different levels of activity and computational complexity. Furthermore, active neurons affect vasodynamics through the process of neurovascular coupling. This allows functional magnetic resonance imaging (fMRI) to infer neuronal processing in humans from changes in blood flow and oxygenation.

We seek to understand how brain-wide neuromodulatory (cholinergic, dopaminergic, etc.) neuronal circuits participate in control of large-scale vasodynamics patterns observed in fMRI experiments in order to infer features of the underlying brain state dynamics from fMRI data.