Ongoing Clinical Trials

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Ongoing clinical trials include:

SUSTAIN: A Phase II Study to Assess Safety and Efficacy of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients with Sickle Cell-Related Pain Crises

An open-label clinical trial to assess the safety and efficacy of macitentan for treatment of pre-capillary pulmonary hypertension in sickle cell disease

Multicenter Registry of Sickle Cell Disease Patients

Biomarker studies of sickle cell disease patients during vasoocclusive events

Recently completed clinical trials include:

  • Neurocognitive studies of sickle cell disease patients
  • Arginine in sickle cell anemia
  • Use of P-selectin blockers in sickle cell anemia