Devlin Moyer

During his undergraduate studies, Devlin worked in a lab at the Cleveland Clinic studying the role of disruptions in pre-mRNA splicing in human diseases. He started out in the wet-lab, but eventually switched to exclusively computational work, helping graduate students in the lab with some analyses of RNA-seq data and independently creating a database of introns in many species to study the evolution of the two classes of spliceosomal introns in eukaryotes. At BU, Devlin is co-advised by Juan Fuxman Bass and Daniel Segrè and his thesis project is about creating a new framework for incorporating expression data into genome-scale metabolic models, with the end goal of building more robust and realistic metabolic models of human cancers. Devlin’s rotation project in the Segrè lab was about combining artificial chemistry and Flux-Balance Analysis to study the general principles governing the structural features of metabolic networks.