Protocols, papers, and links for nucleic acid extraction from human samples without using a “kit.” You can do it! And we can help. Check it out. https://www.bu.edu/klapperich/rna-and-dna-extraction-protocols-and-papers/
Online article! Work with our partners describes a new way to mine the malaria genome to create primer sets that are 100x more sensitive at detecting malaria when compared to Pf18S rRNA primers. The new assay was validated with human samples. Srinivasa Raju, L., Kamath, S., Chandana Shetty, M., Satpathi, S., Mohanty, A. K., Ghosh, […]
George’s tenofovir drug adherence monitoring paper is out. Looking forward to ongoing work in the clinic! Full text at the link: https://www.sciencedirect.com/science/article/pii/S000326701830254X
A fully integrated paperfluidic molecular diagnostic chip for the extraction, amplification, and detection of nucleic acids from clinical samples Abstract Paper diagnostics have successfully been employed to detect the presence of antigens or small molecules in clinical samples through immunoassays; however, the detection of many disease targets relies on the much higher sensitivity and […]
New CFTCC publication out this week at PLoS ONE. Open access links: Kim CS, Vanture S, Cho M, Klapperich CM, Wang C, et al. (2016), “Awareness, Interest, and Preferences of Primary Care Providers in Using Point-of-Care Cancer Screening Technology,” PLoS ONE 11(1): e0145215. doi: 10.1371/journal.pone.0145215 Abstract Well-developed point-of-care (POC) cancer screening tools have the potential to provide better cancer care to patients in both developed and […]
Check out Dr. Klapperich’s commentary on Radio Boston. https://radioboston.wbur.org/2015/10/19/theranos-biotech ….and the op ed on the Commonhealth blog! http://commonhealth.wbur.org/2015/10/theranos-quick-diagnoses
Dr. Wong’s work on improving point of care diagnostics for the detection of TB won first prize in the “Innovations / New Technologies / Improvement Science” track at the annual Consortium of Universities for Global Health Meeting. More info on the work can be found in the following publications: Annals of Global Health Analytical Chemistry
The Klapperich Lab Senior Project Team won second place at the North East Bioengineering Conference last week. Congratulations to Courtney, Nelson, Gil and Danielle!
Colorimetric Detection of Azidothymidine Using an Alkyne-Modified Dextran Substrate George W. Pratt , Andy Fan , and Catherine M. Klapperich * College of Engineering, Boston University, Boston, Massachusetts 02215, United States ABSTRACT Monitoring the adherence of patients taking highly active antiretroviral therapy (HAART) is a key step in treating an HIV infection, especially in resource-limited settings in the developing world. For most […]
Dr. Klapperich is the new Associate Dean for Research and Technology Development in the College of Engineering. See the news story for more information about her new role.