BMERC Seminar on Computational Protein Design

When: Wednesday, June 19, 11 am

Where: ENG room 203, 44 Cummington Street

Title:    Conceptual framework for performing simultaneous fold and sequence optimization of reduced  representation protein models

Speaker: Istvan Kolossvary

D.E. Shaw Research, New York City, NY

Biographical Notes: István Kolossváry graduated with a Ph.D. and an M.Sc. in chemical engineering from the Budapest University of Technology. Prior to joining D.E. Shaw Research, István was an Associate Professor in the Chemistry Department at the Budapest University of Technology, and also served as a Visiting Professor at Columbia University. István was a Senior Research Scientist at the Novartis Institute for Biomedical Research, and made very important contributions to the methodology of conformational searches for large organic molecules. He also founded a research, software development, and scientific consulting company, BIOKOL Research, in 1999.

About D.E. Shaw Research: D.E. Shaw Research is engaged in scientific research in the field of computational biochemistry, including the design of novel algorithms and machine architectures for high-speed molecular dynamics (MD) simulations of proteins and other biological macromolecules. In particular, they have designed and constructed a specialized supercomputer called Anton, which executes such simulations orders of magnitude faster than was previously possible, along with a number of software tools and techniques that facilitate their execution and analysis.