We are interested in-

• The biochemistry, enzymology, molecular human genetics, evolution, metabolomics involving the glycolytic enzyme aldolase
• The structure and function of aldolases
• The characterization of the genetic defects in hereditary fructose intolerance (HFI) and their metabolic consequences
• The evolution of the aldolases and their moonlighting functions in the cell
• The metabolic pathways involving the aldolase isozymes; in particular fructose metabolism