Molecular & Translational Medicine

• GMS MM 701: Genetics and Epidemiology of Disease
  Topics include: Human Genome Structure and Function; Population Genetics; Genetic Risk Assessment; Non-Mendelian Inheritance; Approaches for Studying the Genetics of Complex Traits; Chromosomes and Chromosome Abnormalities; Principles of Cancer Genetics and Genetic Diagnostics; Methods of Human Linkage Analysis; Identifying Human Disease Genes; Genotype-Phenotype Correlations; and Applications of the "New Genetics". 2 cr, Fall sem.
• GMS MM 703: Cancer Biology and Genetics
  This course will cover topics in human tumor biology including: Tumor progression, invasion, and metastasis; Viruses, immunodeficiency, and cancer; Chemical carcinogenesis; Signal transduction; Anti-oncogenes and familial cancer syndromes; Apoptosis and cancer; Cell cycle control; DNA repair; Principles of Cancer Therapy; Immunotherapy of Cancer; Anti-angiogenesis therapy; and modern molecular diagnostic techniques. 2 cr, Fall sem.
• GMS MM 707: Organ System Diseases
  This course will address current topics in the molecular basis of non-malignant and non-immunologic diseases of man in the fields of Cardiovascular Disease; Hemostasis; Metabolic and endocrine diseases; Genetics of renal disease; Pulmonary Disease; Reproductive Disorders and Dermal Diseases. Examples of topics that will be covered include the molecular basis of atherosclerotic heart disease and cardiomyopathy; molecular basis of pre-thrombotic disorders (such as Factor V Leyden); leptins and obesity; mitochondrial dysfunction and cystic fibrosis. 2 cr, Fall sem.
• GMS MM 710: Stem Cells and Regenerative Medicine
  This course is designed to teach basic research and translational research skills to students in the Molecular Medicine Curriculum, using general principles of stem cells and their potential use in regenerative medicine. Students will first be exposed to the basic concepts and definitions of stem cells, the detailed study of different types of adult vs pluripotent stem cells, and discuss ethical and practical considerations. Students will also learn about stem cell manipulation by novel gene editing techniques, recent advances in disease modeling and the potential use of stem cells in tissue and organ regeneration. 2 cr, Spring sem.
• GMS MM 725: Biology of the Lung and Pulmonary Disease
  This course will cover topics in basic lung biology including cellular components and functions in the respiratory system and how the processes of immunity and development influence lung structure and function. The course will apply this basic biology to cutting edge developments in pulmonary diseases including the acute respiratory distress syndrome, pneumonia, asthma, pulmonary hypertension, pulmonary fibrosis, chronic obstructive pulmonary disease and lung cancer. 2 cr, Spring sem.
• GMS MM 730: Biological Core Technologies
  The major goal of this course is to provide an overview of the principles and applications of modern techniques, which are regularly employed in academia and industry as tools for biomolecular and biomedical investigation. This course will focus on technologies which are available at BUSM. Specific technologies include microscopy, FACS, IHC, qPCR, genomic (next gen sequencing and microarrays), proteomics techniques, HTS, fluorescence molecular tomography, ultrasound and metabolic phenotyping techniques. 3 cr, Spring sem.
• GMS MM 901: Molecular Medicine Research
  Var cr
• GMS MM 902: Molecular Medicine Research
  Var cr

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