Molecular Medicine

  • Carmela R. Abraham, PhD (Biochemistry)
    Research interests: Mechanisms of normal brain aging and the etiology of Alzheimer’s disease
  • Kenneth H. Albrecht, PhD (Genetics)
    Research interests: Mammalian gonadal sex determination
  • Deborah Anderson, PhD (General OB/GYN)
    Research interests: Mechanisms of cell-associated HIV transmission and fundamental features of local immune defense functions at genital mucosal surfaces that affect HIV-1 pathogenesis and transmission
  • Clinton T. Baldwin, PhD (Pediatrics)
  • Victoria Bolotina, PhD (Vascular Biology Unit; Ion Channel and Calcium Signaling Unit)
  • Steven C. Borkan, MD (Nephrology)
    Research interests: Cellular mechanisms of ischemic acute kidney injury (AKI)
  • Jerome S. Brody, MD (Pulmonary, Allergy, and Critical Care)
    Research interests: Clinical and basic studies of lung cancer using gene expression profiling
  • Wellington V. Cardoso, MD, PhD (Pulmonary, Allergy, and Critical Care)
    Research interests: Mechanisms that regulate the development of the respiratory system in the mammalian embryo and repair in the adult lung
  • David M. Center, MD (Translational Research)
    Research interests: Nuclear factors associated with control of the CD4+ T cell cycle; functions of pro-Interleukin-16 and its dysregulation in T cell leukemias; effects of Interleukin 16 stimulation of CD4+ T cells
  • David Chui, MD (Hematology and Medical Oncology)
  • Herbert T. Cohen, MD (Nephrology)
    Research interests: Molecular basis of renal cancer, renal cystic disease, and renal development
  • Richard A. Cohen, MD (Cardiovascular Medicine)
    Research interests: The biology and pathophysiology of nitric oxide (NO) in the setting of vascular disease
  • Wilson Colucci, MD (Cardiovascular Medicine)
    Research interests: Mechanisms that mediate myocardial remodeling and failure
  • Barbara E. Corkey, PhD (Gastroenterology)
    Research interests: Modulation of hormone and adipokine exocytosis, electrical activity, metabolism, and gene expression in obesity
  • Catherine Costello, PhD (Biochemistry; Director, Center for Biomedical Mass Spectrometry)
    Research interests: Proteins, glycans and lipids
  • William W. Cruikshank, PhD (Pulmonary, Allergy, and Critical Care; Program Director, Graduate Program in Molecular Medicine)
    Research interests: Characterization, process of synthesis and secretion, and clinical relevance to inflammation of the CD4+ T-cell-specific cytokine interleukin 16 (IL-16)
  • Gerald V. Denis, PhD (Hematology and Medical Oncology)
    Research interests: Effect of the novel transcriptional co-activator, Brd2 in hematological malignancies and obesity
  • Maria Isabel Dominguez, PhD (Hematology and Medical Oncology)
    Research interests: Wnt signaling in embryonic development and cancer
  • Thomas A. Einhorn, MD (General Orthopaedic Surgery)
    Research interests: Effect of pro-inflammatory cytokines, pharmaceuticals, and angiogenic agents on bone and cartilage repair and regeneration
  • Douglas V. Faller, MD, PhD (Hematology and Medical Oncology)
    Research interests: The basic molecular and cellular biology of virus- and oncogene-transformed cells and tumors
  • Lindsay A. Farrer, PhD (Genetics Program)
    Research interests: The genetic basis of complex diseases using genetic mapping methods for locating modifiers of gene expression
  • Alan Fine, MD (Pulmonary; Chair, Admissions Committee)
    Research interests: Lung progenitor cells and the design of therapies for a variety of lung diseases, including asthma, pulmonary hypertension, and interstitial pulmonary fibrosis
  • Susan K. Fried, PhD (Endocrinology, Diabetes, and Nutrition)
  • Caroline Attardo Genco, PhD (Infectious Disease)
    Research interests: Microbial pathogenesis, vaccine development, host- parasite interactions, and bacterial gene regulation
  • Louis C. Gerstenfeld, PhD (General Orthopaedic Surgery; Chair, Tier 1 and 2 Qualifying Committee)
    Research interests: Bone repair after trauma or surgical treatment; how genetic variations affect fracture healing
  • Frank C. Gibson III, PhD (Infectious Disease)
    Research interests: Mechanisms underlying microbial pathogenesis and host-pathogen interactions
  • Jianlin Gong, MD (Hematology and Oncology)
    Research interests: Development of dendritic cell (DC)-based tumor vaccines
  • Diddahally R. Govindaraju, PhD (Neurology)
  • Robert C. Green, MD, MPH (Neurology)
    Research interests: Preclinical detection, treatment and prevention of Alzheimer’s disease
  • James A. Hamilton, PhD (Physiology and Biophysics)
    Research interests: Novel physical approaches to study obesity, metabolic syndrome, and cardiovascular disease
  • Kevan L. Hartshorn, MD (Hematology and Medical Oncology)
  • Andrew J. Henderson, PhD (Infectious Disease)
    Research interests: Cellular signals and the regulation of HIV transcription and replication
  • Victoria Herrera, MD (Cardiology)
    Research interests: Molecular and genetic basis of hypertension and associated diseases
  • Michael F. Holick, MD, PhD (Endocrinology, Diabetes, and Nutrition)
    Research interests: Vitamin D as a chemopreventive agent in prostate, colorectal, and other cancers
  • Robin Ingalls, MD (Infectious Disease)
    Research interests: The innate immune system and pathogen recognition
  • Matthew R. Jones, PhD (Pulmonary; Chair, Journal Club)
  • Mark Klempner, MD (Infectious Disease)
    Research interests: The molecular biology and pathogenesis of Lyme disease
  • Darrell Kotton, MD (Pulmonary, Allergy, and Critical Care)
    Research interests: Embryonic stem cells and lung differentiation
  • Robert A. Lafyatis, MD (Rheumatology)
    Research interests: The pathogenesis of scleroderma
  • Matthew Layne, PhD (Biochemistry)
  • Adam Lerner, MD (Hematology and Medical Oncology)
    Research interests: Lymphoid malignancies and the role of focal-adhesion-associated proteins in breast cancer anti-estrogen resistance
  • Jining Lu, PhD (Pulmonary, Allergy, and Critical Care)
    Research interests: Micro RNAs in lung development and diseases
  • Weining Lu, MD (Nephrology)
    Research interests: Kidney development and the molecular basis of congenital anomalies of the kidney and urinary tract (CAKUT)
  • Zhijun Luo, MD, PhD (Endocrinology, Diabetes, and Nutrition)
    Research interests: Protein phosphorylation as a regulator of cell metabolism and growth
  • Joseph P. Mizgerd, ScD (Pulmonary, Allergy, and Critical Care)
    Research interests: Innate immunity and the pathogenesis of acute lower respiratory tract infections
  • Monty Montano, PhD (Infectious Disease)
    Research interests: Host-pathogen genomics, muscle stem cell biology, and aging
  • Gustavo Mostoslavsky, MD, PhD (Gastroenterology)
    Research interests: Stem cell biology and gene therapy
  • Richard H. Myers, PhD (Neurology)
    Research interests: Application of genetic research methods for the investigation of adult onset diseases with complex etiology (Parkinson’s disease, coronary heart disease, Alzheimer’s disease, osteoarthritis, osteoporosis, etc.)
  • Caryn L. Navarro, PhD (Genetics Program)
    Research interests: Molecular motor activity in cell division, organelle positioning, intracellular transport, vesicle sorting, and intracellular pathogen targeting
  • Barbara S. Nikolajczyk, PhD (Microbiology)
    Research interests: Inflammation in type 2 diabetes and other inflammatory diseases; molecular mechanisms of disease pathogenesis; regulation of IL-1 beta production
  • Matthew Nugent, PhD (Opthalmology, Biomedical Engineering)
    Research interests: control of mammalian cells by interaction of heparin-binding growth factors and the extracellular matrix; regulation of angiogenesis; use of quantitative methods to develop predictive models of living systems to probe basic mechanisms and assist in rational design of new human disease therapies
  • Gwynneth Offner, PhD (Gastroenterology)
    Research interests: Mucin glycoproteins in epithelial protection and repair
  • Paul F. Pilch, PhD (Biochemistry)
    Research interests: Insulin receptor signaling in obesity
  • Lee J. Quinton, PhD (Pulmonary, Allergy, and Critical Care)
  • Vasan Ramachandran, MBBS, MD (Preventive Medicine & Epidemiology)
  • Maria I. Ramirez, PhD (Pulmonary, Allergy, and Critical Care)
    Research interests: Differentiation of lung epithelial cells during mammalian development
  • Katya Ravid, DSc, PhD (Biochemistry and Medicine)
    Research interests: Genetic and signaling factors that control lineage commitment and the regulation of the cell cycle
  • Ian R. Rifkin, MBBCh, PhD (Nephrology)
    Research interests: Mechanisms responsible for the pathogenesis of systemic lupus erythematosus and lupus-associated atherosclerosis
  • Jennifer Rosen, MD (Surgery)
  • Thomas L. Rothstein, MD, PhD (Hematology and Medical Oncology)
  • Sayon Roy, PhD (Endocrinology, Diabetes, and Nutrition)
    Research interests: The pathogenesis of diabetic microangiopathy and vascular complications in diabetic retinopathy and diabetic nephropathy
  • Neil B. Ruderman, MD, PhD (Endocrinology, Diabetes, and Nutrition)
    Research interests: The effects of insulin, exercise and fuels on cellular metabolism, signal transduction, and gene expression
  • Joshua D. Safer, MD (Endocrinology, Diabetes, and Nutrition)
    Research interests: Thyroid hormones and wound healing
  • David J. Salant, MD (Nephrology)
    Research interests: The immune basis of glomerular disease
  • Flora Sam, MD (Cardiovascular Medicine)
  • Jennifer J. Schlezinger, PhD (Environmental Health)
    Research interests: Environmental chemicals as mediators of cell death
  • John H Schwartz, MD (Nephrology)
    Research interests: Transport in renal epithelial cells and ischemic renal disease
  • David C. Seldin, MD, PhD (Hematology and Medical Oncology)
    Research interests: Lymphoproliferative diseases and other malignancies; mechanisms of disease in the plasma cell disorder “systemic amyloidosis”
  • Richard Sherva, PhD (Molecular Medicine—Genetics Program)
  • Orian S. Shirihai, MD, PhD (Molecular Medicine—Obesity)
  • Satish K. Singh, MD (Gastroenterology)
  • Martin H. Steinberg, MD (Hematology and Medical Oncology)
    Research interests: Genetic polymorphisms and sickle cell anemia
  • Sam Thiagalingam, PhD (Molecular Medicine—Genetics Program)
    Research interests: Cancer genomics and multi-modular molecular network (MMMN) cancer progression models
  • Maria Trojanowska, PhD (Rheumatology)
  • Gregory Viglianti, PhD (Microbiology)
    Research interests: Molecular biology of HIV-1; the role of virus-host cell interactions in pathogenesis
  • Kenneth Walsh, PhD (Cardiovascular Medicine)
    Research interests: Signaling—and transcriptional—regulatory mechanisms that control both normal and pathological tissue growth in the cardiovascular system
  • H. Christian Weber, MD (Gastroenterology)
    Research interests: Bombesin receptors in human cancer and obesity
  • Lee M. Wetzler, MD (Infectious Disease)
    Research interests: Vaccine development; microbial immunity and pathogenesis; effect of bacterial products on eukaryotic cells
  • Benjamin L. Wolozin, MD, PhD (Pharmacology and Experimental Therapeutics)
    Research interests: Pathophysiology of neurodegenerative diseases
  • Mohammad H. Zaman, PhD (Biomedical Engineering)
    Research interests: Using cell biology, mechanics, systems biology, and medicine to develop models for tumor invasion and metastasis
  • Mengwei Zang, MD, PhD (Vascular Biology Unit)
    Research interests: Energy homeostasis in diabetes and cardiovascular disease
  • Vassilis Zannis, PhD (Molecular Medicine)
    Research interests: Apolipoproteins in cardiovascular and Alzheimer’s disease