This course emphasizes the molecular and cellular interactions involved in immune response. Topics covered include antibody structure and function; applications of monoclonal antibodies in biotechnology and medicine; gene rearrangements in B and T cells; cellular cooperation and the role of MHC; tolerance; and immunopathology (hypersensitivity, autoimmunity, transplantation, AIDS, cancer immunity and immunotherapy). Lab techniques covered include Flow Cytometry (FACs), ELISA, cell sorting, cell proliferation, cell death, and migration assays. Offered every other year.