Courses

• GMS MI 812: Microbiology Seminar
  Presentation and discussion of problems of current interest. Corley. 2 cr, Fall & Spring sem.
• GMS MI 823: Special Topics in Microbiology
  TBA. Var cr, Spring sem.
• GMS MI 911: Research Microbiology
  Var cr
• GMS MI 912: Research Microbiology
  Var cr
• GMS MM 701: Genetics and Epidemiology of Disease
  Prereq: consent of instructor. This course will address the genetic basis of human disease and the techniques for investigation within this area of research. Topics will include molecular genetics, genetic linkage analysis, candidate gene and genome wide association studies, model organism genetics, cancer genetics, and mitochondrial genetics from the perspective of research study design and disease mechanisms. Farrer. 2 cr, Fall sem.
• GMS MM 703: Cancer Biology and Genetics
  Prereq: consent of instructor. This course will begin with an historical perspective; review the major mechanistic pathways relating to oncogenes, antioncogenes, cell cycle control, repair, and apoptosis; discuss standard and experimental principles of cancer treatment; and conclude with a discussion of cancer epidemiology and health policy issues that affect all basic and translational cancer research. Seldin, Dasgupta. 2 cr, Fall sem.
• GMS MM 705: Immunity and Infection
  Prereq: consent of instructor. The Immunity and Infection course is designed to highlight the application of basic immunological concepts and molecular mechanisms that underlie conditions of immune dysfunction and immune responses to specific microorganisms and viruses. Measurements of immune system integrity that provide the basis for diagnosis will be examined in detail. Immunotherapies that encompass vaccine strategies, cytokine administration, bone marrow transplantation, peptide administration, oral tolerance, anti-idiotype treatment, and gene therapy will be discussed. Genco. 2 cr, Fall sem.
• GMS MM 707: Organ System Diseases
  Prereq: consent of instructor. The Organ System Diseases block is devoted to an exploration of contemporary research on the molecular basis of diseases that do not clearly fit into the rubrics of the first three blocks. Cohen. 2 cr, Fall sem.
• GMS MM 710: Molecules to Molecular Therapeutics
  Prereq: consent of the instructor. This course is designed to provide instruction in all aspects of the translation of basic research observations into clinical applications, using a case study model. The first case study will focus on sickle cell anemia. The second general area for study is diseases of protein folding. Lectures will review the molecular genetics of the disease and explore animal models for study of sickle cell anemia and will include laboratory exercises as appropriate. The course will address treatment strategies for sickle cell disease, including pharmacologic manipulation of globin gene expression, structural biology and rational drug design, and gene therapy. Additional topics related to clinical trials development will be covered including ethical issues, regulatory affairs, statistical considerations in clinical research, and outcome analysis. Required of all molecular medicine graduate students. Seldin, Steinberg. 4 cr, Spring sem.
• GMS MM 730: Biological Core Technologies
  Prereq: GMS CM 753 or BI 755 or BI 782 or consent of instructor. The major goal of this course is to provide an overview of the principles and applications of modern techniques, which are regularly employed in academia and industry as tools for biomolecular and biomedical investigation. This course will focus on technologies which are available at BUSM. Specific technologies include microscopy, FACS, IHC, qPCR, genomic (next gen sequencing and microarrays), proteomics techniques, HTS, fluorescence molecular tomography, ultrasound and metabolic phenotyping techniques. Offered alternate years. Ravid, Haigh, Molina. 2 cr, Fall sem.
• GMS MM 901: Molec MED Res
  
• GMS MM 902: Molec MED Res
  
• GMS MS 506: Clinical Laboratory Genetics I
  Prereq: Biology or Genetics course. Advanced course designed for those considering a clinical or research career in human genetics. Emphasis is on clinical cytogenetics (chromosome testing). Course will cover types of chromosome abnormalities, methodology, nomenclature and clinical significance in pregnancy, birth defects, and cancer. Laboratory work will include basic blood culture, chromosome preparation, banding, identification and karyotyping. Provides updated review of latest cytogenetic methodology and applications, such as FISH, comparative genomic hypridization (CGH) and array CGH. Wyand. 4 cr, SS I.
• GMS MS 571: Ds/Rel MED Sci
  
• GMS MS 572: Ds/Rel MED Sci
  
• GMS MS 610: Ethico-legal Issues of Bioscience
  This course examines evolving ethical and legal issues in medicine and genetics. Students will study existing laws, legal cases pertaining to topics such as genetic testing, gene therapy, medicine, drug development and politics. Class discussions, student presentations, case analysis and in-class lectures will be supplemented with online activities as well as the composition of a legal brief. Open to all students registered in GMS programs, including health law students. Yashon. 4 cr, Fall sem.
• GMS MS 620: Technology Commercialization
  The subject of this course is the innovative transformation of knowledge into commercial products and services. Cross-disciplinary teams of students will assess real technologies for their commercial potential in terms of licensing and/or for venture development. Offered in alternate years (not offered in 2010). Stevens. 4 cr, Fall sem.
• GMS MS 621: Bench-to-Bedside--Translating Biomedical Innovation from the Laboratory to the Marketplace
  This course covers intellectual property, licensing, and the core aspects of planning, creating, funding, and building new entrepreneurial ventures. Cross-disciplinary teams are formed to evaluate current BU translational research projects and their potential as the basis for a start-up company. Gupta. 4 cr, Fall sem.
• GMS MS 640: Introduction to Biomedical Information
  (Required course for M.A. in Medical Sciences students). This course teaches how to find, use, and contribute to biomedical literature while supporting the graduate thesis through lectures and hands-on instruction. Topics include the retrieval, evaluation and management of information, Evidence Based Medicine, and the ethical use of research. Davies, Flynn. 2 cr, Spring sem.
• GMS MS 642: Current Issues in Assisted Reproduction and Infertility
  A steady rise in infertility has forced medical science to develop Assisted Reproductive techniques. Discussion of cases, media involvement and medical intervention will be part of this course. A comparison of regulations in the US and UK as well as other countries is emphasized. It will look closely at the legal and ethical questions raised by assisted reproduction and infertility as well as look toward the future. Class discussions, student presentations, case analysis and in-class lectures will be supplemented with online activities as well as the composition of a legal brief. Open to all students registered in GMS programs, including health law students. Yashon. 2 cr, Spring sem.

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