Julie R. Palmer, ScD, MPH

Karin Grunebaum Professor in Cancer Research
Boston University Chobanian & Avedisian School of Medicine
Professor of Epidemiology
Boston University School of Public Health
jpalmer@bu.edu
Education:
BA, Brown University
MPH, Boston University
ScD, Harvard University
Research Interests:
Dr. Palmer’s cancer research spans early detection, etiology, and survivorship. Her primary focus is on elucidating reasons for the disproportionately high incidence of hormone receptor negative breast cancer in U.S. Black women and on reducing racial disparities in breast cancer mortality. She is a founding leader of the Black Women’s Health Study (BWHS), a prospective cohort study of 59,000 self-identified Black women who enrolled in 1995 and have been followed by biennial questionnaire since that time. Her breast cancer research within the BWHS includes work on risk prediction models for breast cancer in U.S. Black women, identifying differences in childbearing patterns as a contributing cause to the excess incidence of estrogen receptor negative breast cancer in Black women, and investigating the interrelationships of type 2 diabetes, obesity, and inflammation on breast cancer risk. Her recent grants have supported work on somatic mutations, epigenetics, and gene expressions profiles in breast cancer tumors from Black women, setting the stage for a better understanding of the role of epidemiologic and genetic factors in etiology and prognosis. Dr. Palmer has served on many NIH and external advisory committees, including as Chair of the NIH Cancer, Cardiovascular, and Sleep Epidemiology Study Section, 2015-2017, and Co-Chair of a Working Group for the National Cancer Advisory Board, NCI, 2018-2019. Dr. Palmer was awarded the AACR Distinguished Lectureship on the Science of Cancer Health Disparities in 2017. She has served as a Komen Scholar since 2018 and as a Breast Cancer Research Foundation Investigator since 2023.
Active research grants:
- A Follow-up Study for Causes of Cancer in Black Women
09/01/2022 – 08/31/2027 (Contact PI)
NIH/National Cancer Institute
5U01CA164974-15
- Evaluating the Feasibility of Lung Cancer Screening in High-risk Black Women
08/01/2023 – 07/31/2026 (Multi-PI)
Massachusetts General Hospital HHS AHRQ
5R18HS029430-02
- Breast Cancer Drivers in Black Women: Society to Cells
11/01/2023 – 09/30/2026 (PI)
Breast Cancer Research Foundation
- Somatic Mutations and Their Etiological Determinants for Breast Cancer in African American Women
02/01/2019 – 01/31/2026 (Multi-PI)
Health Research, Inc. NIH NCI
5R01CA228156-05
- American Cancer Society Institutional Research Grant
01/01/2023 – 12/31/2025 (PI)
American Cancer Society, Inc.
- Testing scalable communication modalities for returning breast cancer genetic research results to African American women
06/12/2020 – 11/30/2025 (Multi-PI)
NIH/National Inst on Minority Health and Health Disparities
5R01MD014312-04
- Psychosocial stress and molecular profiles of breast tumors from U.S. Black women
10/26/2022 – 10/25/2025 (PI)
Susan G. Komen for the Cure
- Advancing breast cancer risk prediction in national cohorts: the role of mammogram-based deep learning
09/21/2023 – 08/31/2026 (Co-I))
Trustees Of Columbia University In The City Of New York ← NIH NCI
5U01CA276553-02
Selected recent publications:
- Yao S, Wei L, Hu Q, Liu S, Manojlovic Z, Fiorica PN, Long M, Zirpoli GR, Cai Q, Long J, Ping J, Barnard ME, Jin Y, Murakami M, Wang J, Zhu Q, Davis W, Chen J, Ondracek RP, Khoury T, Gandhi S, Takabe K, Ko N, Sanderson M, Hong CC, Bandera EV, Craig DW, Ambrosone CB, Palmer JR, Zheng W, Carpten JD. Mutational landscape of triple-negative breast cancer in African American women. Nat Genet. 2025 Sep; 57(9):2166-2176.PMID: 40858906; DOI: 10.1038/s41588-025-02322-y;
- Ambrosone CB, Yao S, Long MD, Liu C, Chen J, Davis W, Zirpoli G, Payne-Ondracek R, Khoury T, Gong Z, Hu Q, Szewczyk S, Omilian AR, Bandera EV, Liu S, Kushi L, Higgins MJ, Palmer JR. Associations of DNA methylation in breast tumour subtypes with parity and breastfeeding in a cohort of 1459 Black women: implications for public health. BMJ Oncol. 2025; 4(1):e000675.PMID: 40519219; PMCID: PMC12164313; DOI: 10.1136/bmjonc-2024-000675;
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Shan Y, Bertrand KA, Petrick JL, Sheehy S, Palmer JR. Planetary Health Diet Index in relation to mortality in a prospective cohort study of United States Black females. Am J Clin Nutr. 2025 Mar; 121(3):589-596.PMID: 39863116; PMCID: PMC11923421; DOI: 10.1016/j.ajcnut.2025.01.023;
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Jia G, Ping J, Guo X, Yang Y, Tao R, Li B, Ambs S, Barnard ME, Chen Y, Garcia-Closas M, Gu J, Hu JJ, Huo D, John EM, Li CI, Li JL, Nathanson KL, Nemesure B, Olopade OI, Pal T, Press MF, Sanderson M, Sandler DP, Shu XO, Troester MA, Yao S, Adejumo PO, Ahearn T, Brewster AM, Hennis AJM, Makumbi T, Ndom P, O’Brien KM, Olshan AF, Oluwasanu MM, Reid S, Butler EN, Huang M, Ntekim A, Qian H, Zhang H, Ambrosone CB, Cai Q, Long J, Palmer JR, Haiman CA, Zheng W. Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction. Nat Genet. 2024 May; 56(5):819-826.PMID: 38741014; PMCID: PMC11284829; DOI: 10.1038/s41588-024-01736-4;
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Potter AL, Xu NN, Senthil P, Srinivasan D, Lee H, Gazelle GS, Chelala L, Zheng W, Fintelmann FJ, Sequist LV, Donington J, Palmer JR & Yang CJ. Pack-Year Smoking History: An Inadequate and Biased Measure to Determine Lung Cancer Screening Eligibility. J Clin Oncol. 2024 Jun 10; 42(17):2026-2037. PMID: 38537159; PMCID: PMC11191064; DOI: 10.1200/JCO.23.01780;
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Ruiz-Narváez EA, Cozier Y, Zirpoli G, Rosenberg L, Palmer JR. Perceived Experiences of racism in Relation to Genome-Wide DNA Methylation and Epigenetic Aging in the Black Women’s Health Study. J Racial Ethn Health Disparities. 2025 Apr; 12(2):754-763. PMID: 38324238; PMCID: PMC11303595; DOI: 10.1007/s40615-024-01915-3;
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Zirpoli GR, Pfeiffer RM, Bertrand KA, Huo D, Lunetta KL, Palmer JR. Addition of polygenic risk score to a risk calculator for prediction of breast cancer in US Black women. Breast Cancer Res. 2024 Jan 02; 26(1):2. PMID: 38167144; PMCID: PMC10763003; DOI: 10.1186/s13058-023-01748-8;
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Barnard ME, Wang X, Petrick JL, Zirpoli GR, Jones D, Johnson WE, Palmer JR. Psychosocial stressors and breast cancer gene expression in the Black Women’s Health Study. Breast Cancer Res Treat. 2024 Apr; 204(2):327-340.PMID: 38127176; PMCID: PMC11232497; DOI: 10.1007/s10549-023-07182-w;
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Palmer JR, Cozier YC, Rosenberg L. Research on Health Disparities: Strategies and Findings from the Black Women’s Health Study. Am J Epidemiol. 2023 Nov 03; 192(11):1806-1810.View Related Profiles. PMID: 35136921; PMCID: PMC11004793; DOI: 10.1093/aje/kwac022;
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Bertrand KA, Delp L, Coogan PF, Cozier YC, Lenzy YM, Rosenberg L, Palmer JR. Hair relaxer use and risk of uterine cancer in the Black Women’s Health Study. Environ Res. 2023 Dec 15; 239(Pt 1):117228.View Related Profiles. PMID: 37821068; PMCID: PMC10842360; DOI: 10.1016/j.envres.2023.117228;
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Wang C, Bertrand KA, Trevino-Talbot M, Flynn M, Ruderman M, Cabral HJ, Bowen DJ, Hughes-Halbert C, Palmer JR. Ethical, legal, and social implications (ELSI) and challenges in the design of a randomized controlled trial to test the online return of cancer genetic research results to U.S. Black women. Contemp Clin Trials. 2023 Sep; 132:107309.PMID: 37516165; PMCID: PMC10544717; DOI: 10.1016/j.cct.2023.107309;
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Sheehy S, Aparicio HJ, Xu N, Bertrand KA, Robles YP, Lioutas VA, Shulman JG, Rosenberg L, Palmer JR. Hypertensive Disorders of Pregnancy and Risk of Stroke in U.S. Black Women. NEJM Evid. 2023 Oct; 2(10):EVIDoa2300058.PMID: 38320178; PMCID: PMC10919377; DOI: 10.1056/EVIDoa2300058;
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Young KL, Olshan AF, Lunetta K, Graff M, Williams LA, Yao S, Zirpoli GR, Troester M, Palmer JR. Influence of alcohol consumption and alcohol metabolism variants on breast cancer risk among Black women: results from the AMBER consortium. Breast Cancer Res. 2023 Jun 12; 25(1):66. PMID: 37308906; PMCID: PMC10259046; DOI: 10.1186/s13058-023-01660-1;
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Schedin P, Palmer JR. Can Breast Cancer Prevention Strategies Be Tailored to Biologic Subtype and Unique Reproductive Windows? J Natl Cancer Inst. 2022 Dec 08; 114(12):1575-1576. PMID: 35723566; PMCID: PMC9745422; DOI: 10.1093/jnci/djac114;
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Davis Lynn BC, Lord BD, Cora R, Pfeiffer RM, Lawrence S, Zirpoli G, Bethea TN, Palmer JR & Gierach GL. Associations between quantitative measures of TDLU involution and breast tumor molecular subtypes among breast cancer cases in the Black Women’s Health Study: a case-case analysis. Breast Cancer Res. 2022 Dec 05; 24(1):86.View Related Profiles. PMID: 36471360; PMCID: PMC9720909; DOI: 10.1186/s13058-022-01577-1;
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Potter AL, Yang CJ, Woolpert KM, Puttaraju T, Suzuki K, Palmer JR. Evaluating Eligibility of US Black Women Under USPSTF Lung Cancer Screening Guidelines. JAMA Oncol. 2022 01 01; 8(1):163-164. PMID: 34817564; PMCID: PMC8777560; DOI: 10.1001/jamaoncol.2021.5790;
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Barber LE, Zirpoli GR, Cozier YC, Rosenberg L, Petrick JL, Bertrand KA, Palmer JR. Neighborhood disadvantage and individual-level life stressors in relation to breast cancer incidence in US Black women. Breast Cancer Res. 2021 11 22; 23(1):108.View Related Profiles. PMID: 34809694; PMCID: PMC8609879; DOI: 10.1186/s13058-021-01483-y;
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Palmer JR, Zirpoli G, Bertrand KA, Battaglia T, Bernstein L, Ambrosone CB, Bandera EV, Troester MA, Rosenberg L, Pfeiffer RM, Trinquart L. A Validated Risk Prediction Model for Breast Cancer in US Black Women. J Clin Oncol. 2021 12 01; 39(34):3866-3877.View Related Profiles. PMID: 34623926; PMCID: PMC8608262; DOI: 10.1200/JCO.21.01236;
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Domchek SM, Yao S, Chen F, Hu C, Hart SN, Goldgar DE, Nathanson KL, Ambrosone CB, Haiman CA, Couch FJ, Polley EC, Palmer JR. Comparison of the Prevalence of Pathogenic Variants in Cancer Susceptibility Genes in Black Women and Non-Hispanic White Women With Breast Cancer in the United States. JAMA Oncol. 2021 07 01; 7(7):1045-1050. PMID: 34042955; PMCID: PMC8160931; DOI: 10.1001/jamaoncol.2021.1492;
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Palmer JR, Polley EC, Hu C, John EM, Haiman C, Hart SN, Gaudet M, Pal T, Anton-Culver H, Trentham-Dietz A, Bernstein L, Ambrosone CB, Bandera EV, Bertrand KA, Bethea TN, Gao C, Gnanaolivu RD, Huang H, Lee KY, LeMarchand L, Na J, Sandler DP, Shah PD, Yadav S, Yang W, Weitzel JN, Domchek SM, Goldgar DE, Nathanson KL, Kraft P, Yao S, Couch FJ. Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women. J Natl Cancer Inst. 2020 12 14; 112(12):1213-1221.View Related Profiles. PMID: 32427313; PMCID: PMC7735769; DOI: 10.1093/jnci/djaa040;