Grafting hope
Page 4

...like a bacteria colony on top of a layer of animal collagen. The collagen is soaked in a special mix of nutrients that allow the epithelium to fully form, resulting in a piece of functional pseudo skin that can feed off of its own nutrients until it merges with the body’s blood flow. The result is a visibly perfect replica. This technique is expected to move into clinical trials in 2005.

For now, Sheridan expects that Lisa will have to make due with silicon grafts that only reduce scarring. Instead, she’ll work with a therapist who will teach her exercises that will bend and stretch the scar tissue while it is forming, so there will be enough elasticity for her to move. She’s young enough that as she gets older and her skin continues to grow, doctors will be able to cut areas of scar tissue out of her skin. They’ll then stretch and sew the loose ends back together, leaving a seam instead of a scar patch.

For the areas that will never be removed or grafted over, Lisa has several options to help lessen the appearance of scarred tissue, said Peter Lorenz, an associate professor of plastic surgery at Stanford University. Dermabrasion uses a hand-held grinding tool to sand off the top layer scar tissue, giving a smoother appearance to rough scars. Laser resurfacing does the same thing by disintegrating away the top portion of the scars. To flesh out any discolorations, micropigmentation uses needles to deliver tiny amounts of pigment into the skin, a process similar to tattooing. Lorenz is also currently working with a regiment of steroids that, when injected, begins a hormonal reaction that melts the collagen inside large and lumpy scars, not only flattening them out, but also making them more elastic.

Tonight, Lisa’s alive and sleeping with her two parents watching her from the foot of her bed. The future will hold years of surgeries and therapy. There will always be scars. But those scars won’t stop her life. They won’t keep her from playing sports or dating.

Sheridan is optimistic. “Now is when it all starts. What we plan to do for her tonight will affect how she lives the rest of her life,” he says. “But there’s no telling what new improvement we might be able to use next year to help her out.” He pauses. “As the future comes, her life will get better and better.” r
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