Hengye Man

Professor of Biology

  • Title Professor of Biology
  • Education Ph.D., University of Toronto

Our research interests are focused on brain development, especially neuronal migration, morphogenesis, synapse formation, glutamate receptors and synaptic plasticity. We aim to understand the cellular and molecular processes implicated in developmental disorders including autism, Angelman syndrome, intellectual disability, as well as neurodegenerative diseases including Alzheimer’s disease. We use diverse techniques including biochemistry, immunofluorescent staining, live imaging, virus injection, in utero electroporation, electrophysiology and animal behavior tests. We are currently working on the following directions including (1) AMPA receptor (AMPAR) trafficking and receptor protein stability regulation by ubiquitination and acetylation, (2) homeostatic synaptic plasticity (HSP), and (3) neurobiology of Autism Spectrum Disorders (ASD) focusing on ASD-related genes including KIAA2022/KIDLIA and Ube3A/E6AP.

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Research Areas
Biochemistry, Cell Biology, Imaging, and Neurobiology
Biology and Faculty

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