Assistant Professor, Biology, College of Arts & Sciences
- PhD, Biophysics, Harvard University
BA, Biochemistry and Molecular Biology, Statistics, Rutgers University
- Kilachand Center, Room 605B
Wunderlich and her lab team are studying gene regulatory networks, which are required for virtually every process in an animal from development to immunity. Specifically, they are exploring how a gene regulatory network’s tasks influence its architecture, robustness, and evolvability. To probe these questions, Wunderlich uses two model systems: the Drosophila early embryonic patterning system and the Drosophila innate immune response. In both systems, her team pairs imaging-based and genomic measurements of gene expression with statistical and physically-based computational models to explore questions of gene regulatory network function. They exploit naturally occurring sequence variation between individuals and species as a tool to measure how changes in regulatory DNA affect transcriptional regulation.
regulation of gene expression, design principles of enhancers, systems biology, developmental biology, innate immunology