Publications

2013

  • Wesemann, DR, AJ Portuguese, RM Meyers, MP Gallagher, K Cluff-Jones, JM Magee, RA Panchakshari, SJ Rodigs, TB Kepler, FW Alt (2013) Microbial colonization influences early B-lineage development in the gut lamina propria. Nature 501: 112–115. doi:10.1038/nature12496.
  • Kepler TB. (2013) Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors [v1; ref status: indexed, http://f1000r.es/z6] F1000Research2:103 (doi: 10.12688/f1000research.2-103.v1).
  • Liao, H-X, R Lynch, T Zhou, F Gao, SM Alam, SD Boyd, AZ Fire, KM Roskin, CA Schramm, Z Zhang, J Zhu, L Shapiro, JC Mullikin, S Gnanakaran, P Hraber, K Wiehe, G Kelsoe, G Yang, S-M Xia, DC Montefiori, R Parks, KE Lloyd, RM Scearce, KA Soderberg, M Cohen, G Kamanga, MK Louder, LM Tran, Y Chen, F Cai, S Chen, S Moquin, X Du, MG Joyce, S Srivatsan, B Zhang, A Zheng, GM Shaw, BH Hahn, TB Kepler, BTM Korber, PD Kwong, JR Mascola, BF Haynes (2013) Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature 496, 469-476. doi:10.1038/nature12053.
  • Ciupe, SM, BH Devlin, LM Markert, TB Kepler (2013) Quantification of total T-cell receptor diversity by flow cytometry and spectratyping, BMC Immunology 14:35. doi: 10.1186/1471-2172-14-35.
  • Yang G, TM Holl,Y Liu, Y Li, X Lu, NI Nicely, TB Kepler, SM Alam, HX Liao, DW Cain, L Spicer, JL Vandeberg, BF Haynes, G Kelsoe (2013) Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies. J. Exp. Med. 210: 241-56. doi: 10.1084/jem.20121977.
  • Chan C, M Billard, S Ramirez, H Schmidl, E Monson, and TB Kepler (2013) A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields. Bull. Math. Biol. 75: 185-205. doi: 10.1007/s11538-012-9799-9.
  • H-X Liao, M Bonsignori, SM Alam, JS McLellan, GD Tomaras, MA Moody, DM Kozink, K-K Hwang, X Chen, C-Y Tsao, P Liu, X Lu, RJ Parks, DC Montefiori, G Ferrari, J Pollara, M Rao, KK Peachman, S Santra, NL Letvin, N Karasavvas, Z-Y Yang, K Dai, M Pancera, J Gorman, K Wiehe, NI Nicely, S Rerks-Ngarm, S Nitayaphan, J Kaewkungwal, P Pitisuttithum, J Tartaglia, F Sinangil, JH Kim, NL Michael, TB Kepler, PD Kwong, JR Mascola, GJ Nabel, A Pinter, S Zolla-Pazner BF Haynes (2013) HIV-1 Vaccine Induces Antibodies Against a V1/V2 Structurally Heterogeneous Site of Immune Pressure. Immunity 38: 176-86. PMC3569735. doi: 10.1016/j.immuni.2012.11.011.

2012

  • Schmidt AG, H Xu, AR Khan, T O’Donnell, S Khurana, LR King, J Manischewitz, H Golding, P Suphaphiphat, A Carfi, E Settembre, PR Dormitzer, T B Kepler, R Zhang, MA Moody, BF Haynes, HX Liao, DE Shaw, SC Harrison (2012) Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proc Natl Acad Sci USA 110: 264-9. PMC3538208.
  • Manolopoulou I, TB Kepler, DM Merl (2012) Mixtures of Gaussian wells: Theory, computation, and application. Comput Stat Data Anal, 56:3809-3820. PMC3384503.
  • Haynes BF, G Kelsoe, SC Harrison, TB Kepler (2012) B Cell Lineage Immunogen Design: A New Approach To Vaccine Development. Nat Biotech, 30: 423-433. PMC3512202.
  • Manolopoulou I, Matheu MP, Cahalan MD, West M, Kepler TB (2012) Bayesian spatio-dynamic modelling in cell motility studies: Learning nonlinear taxic fields guiding the immune response. J Am Stat Assoc. 499: 855-65. doi:10.1080/01621459.2012.655995
  • Bonsignori M, Montefiori DC, Wu X, Chen X, Hwang KK, Tsao CY, Kozink DM, Parks RJ, Tomaras GD, Crump JA, Kapiga SH, Sam NE, Kwong PD, Kepler TB, Liao HX, Mascola JR, Haynes BF (2012) Two Distinct Broadly Neutralizing Antibody Specificities of Different Clonal Lineages in a Single HIV-1-infected Donor: Implications for Vaccine Design. J. Virol. 86: 4688-92. PMC3318651.

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