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- Photonics Forum: Dr. Charles Lin, MGH10:00 am
- Is an SBIR Grant Right for You?12:00 pm
- Jane Baxter (CAS'93)"Reflections on 25 years of the Archaeology of Childhood”12:00 pm
- Allies’ Contributions to America’s Wars: Free Rides or Shared Burdens?12:00 pm
- Unleash the Power of Your BU Network [Webinar]12:00 pm
- Summer 2020 UROP Application Deadline12:00 pm
- NeMLA 51st Annual Convention12:00 pm
- Mosaic Series: Women’s History Month Concert12:30 pm
- Bioinformatics Sponsored Systems Biology Seminar12:45 pm
- The Adjudicatory Mandate of the Inter-American Commission: Litigation in the Inter-American System1:00 pm
- CRC BIOMETRIC WORKSHOPS: Facial Expression Analysis1:00 pm
- Women in Terrorism: Visibility, Legitimacy, and Responsibility in Modern War with Meredith Loken4:00 pm
- Almost sure well-posedness for some dispersive initial value problems (Gigliola Staffilani - MIT)4:00 pm
- Salesforce in Higher Ed Institutions and Non-Profit Organizations4:00 pm
- Book Club4:15 pm
- A Million Little Things: Screening and Q&A5:00 pm
- Mind, Body, and Spirit Yoga5:00 pm
- Pitch & Pizza: Round 1, BU New Venture Competition5:00 pm
- Asia: Post-Colonial Decolonization of Community Design in Hawai'i and Taiwan5:00 pm
- AI and 5G Discussion 5:30 pm
- Deaf World Lecture Series: Wyatte Hall, PHD 6:00 pm
- Science Programs Info Session 6:00 pm
- Tom Fitzgerald & Lorenzo Marquez On Rupaul's Drag Race & "Legendary Children"6:00 pm
- Boston University Wind Ensemble8:00 pm
Photonics Forum: Dr. Charles Lin, MGH
Intravital microscopy (IVM) is an enabling tool for visualizing cellbiology in vivo without removing cells from their native environment. Itis ideally suited to research involving animal models of human diseasesand provides deeper insights into how diseases progress and respond totherapy than is possible with human studies. In particular, by imagingmodels in which specific pathways are targeted using genetic orpharmacologic manipulations, or imaging animals engineered to expressfluorescent proteins as reporters of specific activities, IVM has madefundamental contributions to the elucidation of key cellular andmolecular pathways. However, as the field is rapidly embracing highthroughput techniques (e.g. massively parallel single cell sequencing) toprofile systems of pathways rather than individual pathways, we need torethink the role of IVM and align it with the needs of the new researchparadigm. Here, Dr. Lin will describe his attempt at integrating thespatial and temporal information provided by IVM with the high contentmolecular information provided by single cell RNA sequencing. His newoptical platform enables spatially-resolved molecular profiling underimage guidance. Preliminary results profiling leukemia cells in the bonemarrow will be presented.Dr. Charles Lin is the Principal Investigator at the MGH Center forSystems Biology and the Wellman Center for Photomedicine. Hislaboratory focuses on the development of advanced optical techniquesfor in vivo cell tracking and molecular imaging studies, concentrating oncharacterizing the bone marrow microenvironment and trackinghematopoietic cells from their origin in the bone marrow to theperipheral circulation and the central nervous system. He received hisB.S. in Chemistry from Yale University and his Ph.D. in PhysicalChemistry from University of Chicago.
When | 10:00 am to 11:30 am on Thursday, March 5, 2020 |
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Location | 9th Floor Room 901 Photonics Center, 8 Saint Mary’s Street |