Special Bioinformatics Seminar
Special Bioinformatics Seminar
Monday 4/28 @ 5:30 pm LSEB B01 – 24 Cummington Mall
Analytical Challenges in Clinical Cancer Diagnostics by NGS
Doron Lipson, PhD
Senior Director, Computational Biology Methods at Foundation Medicine in Cambridge
Dr. Lipson has over 10 years of experience in developing genomic applications. He is currently leading a team responsible for developing clinical-grade computational methods for detecting driver alterations in tumors from NGS data at Foundation Medicine. Previously, he has worked at Helicos BioSciences and at Agilent, and was a co-founder of ProteOptics, which was acquired by Bio-Rad in 2006. Dr. Lipson received his Ph.D. in Computer Science from Israel Institute of Technology, and his B.S. in Computer Science and Biology from the Hebrew University of Jerusalem.
Recent Publications
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas Nature Communications / 20 January 2014
A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma Clinical Cancer Research / 1 January 2014
BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition Clinical Cancer Research / 15 December 2013
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer Nature Medicine / 27 October 2013
Nature Biotechnology / 20 October 2013
Relapsed classic E-cadherin (CDH1) mutated invasive lobular breast cancer demonstrates a high frequency of HER2 (ERBB2) gene mutations Clinical Cancer Research / 10 April 2013
Host: Simon Kasif
Read Esther Rheinbay’s paper in Cell
Esther Rheinbay’s dissertation research was published online April 10. You can read, Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells, here or in the April 24th edition of Cell.
Prof. Korolev’s article about the population dynamics of cancer
Prof. Kirill Korolev's opinion article, Turning ecology and evolution against cancer, was published online April 17 in the journal Nature Reviews Cancer. The piece was co-authored by J. B. Xavier (MSKCC) and J. Gore (MIT) and you can read it here.
Elham Azizi to receive award in Best Student Paper Competition
Congratulations to Elham Azizi! Elham will be receiving an award in the Best Student Paper Competition at the upcoming New England Statistics Symposium (NESS) for her paper in the Galagan Lab, Learning Modular Structures from Network Data and Node Variables. The 28th NESS conference is being hosted by the Harvard School of Public Health and will be held on April 25-26. Well done Elham!
Teresa Wang’s e-cigarette research in the Spira-Lenburg Lab
Teresa Wang’s work in Avi Spira and Marc Lenburg’s lab was presented by co-author Stacy J. Park from UCLA at the annual American Association for Cancer Research meeting held in San Diego this month. The abstract, The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation, has been gaining lots of attention this week, including this feature in Nature.
New Publication by Chetanya Pandya
Congratulations to Chetanya Pandya for his work with Karen Allen and Brandon Xia. Their new paper was published on February 27th in Proteins: Structure, Function, and Bioinformatics. Read it here: Structure-guided approach for detecting large domain inserts in protein sequences as illustrated using the haloacid dehalogenase superfamily Great job!
New Publication by Yevgeniy Gindin
Yevgeniy Gindin's work in Paul Meltzer's lab in the Center for Cancer Research at the NIH has been published on molecular systems biology. The new paper was published in the March 28th issue and you can read it here: A chromatin structure‐based model accurately predicts DNA replication timing in human cells, Great work, Dr. Gindin!
BU Bioinformatics Admissions and Recruitment Reception
October 22, 2014 from 4:30 – 7 pm
LSEB Lobby – Life Science and Engineering Building - 24 Cummington Mall
An opportunity for prospective students to learn about the MS and PhD Programs in Bioinformatics, as well as an MS Program, focusing on bioinformatics for translational medicine.
We will have faculty, students and staff available for informal discussions about our research, PhD fellowships, MS scholarships, curricula and the admissions process.
Who Should Attend?
Bioinformatics is an interdisciplinary field that draws from biology, systems engineering , chemistry, genetics/genomics , physics, mathematics/statistics and computer science, among others. Students with a strong background in either the biological or computational sciences are encouraged to attend.
BU Bioinformatics is committed to supporting highly qualified women, racial and ethnic minorities, persons with disabilities, and other individuals who are underrepresented in STEM. Several travel grants are available for students to travel to Boston to learn about our Program.
New Publication by Vinay Kartha
Congratulations to Vinay Kartha for his work in Rick Myers' lab at the BUSM. The new paper is published in the February 27th issue of PLOS Genetics. MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis. Great work!
improvscience is coming to Bioinformatics
Instructors Mia Anderson and Raquell Holmes from improvscience will be conducting a Professional Presentations workshop for students in BU Bioinformatics on March 21 and 24. Students will take part in exercises to improve their audience interaction and help develop their unique style of performing a scientific talk. Dr. Holmes was recently interviewed in Nature. The article, “Communication: Spontaneous Scientists” is featured in the NatureJobs section and you can read it here: www.nature.com/nature/journal/v505/n7481/full/nj7481-121a.html.
