Undergraduate Prerequisites: ENG BE 403 and Junior standing in BME - Mathematical analysis of feedback control systems. Frequency domain methods including transfer functions, stability, root locus, frequency response. Controller design. State space approaches. Emphasis on models of biological and biomedical systems. Controllability, observability. Emphasis on models of biological and biomedical systems. Cannot be taken for credit in addition to ENG ME 403, ENG ME 404, or ENG EC 402.