The world's countries--low-income nations in particular--face numerous health challenges, including fighting Ebola and other infectious diseases, combating the AIDS pandemic, reducing the incidence of maternal death in childbirth, strengthening national health systems and managing a complex global health architecture. This course will examine these and other issues with an emphasis on how you as an actor in global health can intervene to improve health conditions for the poor. In the first part of the course we will consider some of the fundamental difficulties in health governance, including expanding health coverage, the role of the World Health Organization in governing global health, and how we should be setting global health priorities. We will then move on to consider a set of health challenges that have particular impact upon the poor: HIV/AIDS, Ebola, maternal mortality, female circumcision and non-communicable diseases.