Synthesis, structure, function, regulation of macromolecules (DNA, RNA, protein). Prokaryotic and eukaryotic molecular biology. Topics include: replication, repair, recombination, transcription, translation, 5-methylcytosine, transcription factors, DNA looping (enhancer- promoter, insulator, etc.), histone modification/chromatin remodeling, non-coding RNA. Discussion of genetic and recombinant DNA techniques, including CRISPR/Cas9.