This course melds traditional machine component design with the design, instrumentation, and control of high precision, computer-controlled automation systems, using concrete examples drawn from the photonics, biotech, and semi-conductor industries. Topics covered include design strategy, high-precision mechanical components, sensors and measurement, servo control, design for controllability, control software development, controller hardware, as well as automated error detection and recovery. Students will work in teams, both in classroom and out-of-classroom, to integrate and apply the material covered in class to a term-long multi-part design project, using modern CAD tools, culminating in a group presentation at the end of the semester.