Immunology Training Program

• David M. Center, MD
  Research interests: Nuclear factors associated with control of the CD4+ T cell cycle; functions of pro-Interleukin-16 and its dysregulation in T cell leukemias; effects of Interleukin 16 stimulation of CD4+ T cells
• John H. Connor, PhD
  Research interests: Protein synthesis in virus replication
• Ronald B. Corley, PhD
  Research interests: B lymphocyte development and differentiation; antibody assembly, trafficking, and secretion
• William Cruikshank, PhD
  Research interests: Characterization, process of synthesis and secretion, and clinical relevance to inflammation of the CD4+ T-cell-specific cytokine interleukin 16 (IL-16)
• Gerald Denis, PhD
  Research interests: Effect of the novel transcriptional co-activator, Brd2 in hematological malignancies and obesity
• Hans Dooms, PhD
  Research interests: T cells, autoimmunity, cytokines, immunologic memory, type 1 diabetes
• Douglas V. Faller, MD, PhD
  Research interests: Effects of oncogenes on signal transduction, cellular growth and differentiation, apoptosis, and the cellular immune system
• Rachel Fearns, PhD
  Research interests: Host Pathogen interactions; virus molecular biology
• Lisa Ganley-Leal, PhD
  Research interests: Defining immune correlates of protection in human schistosomiasis
• Caroline A. Genco, PhD
  Research interests: Microbial pathogenesis, vaccine development, host- parasite interactions, and bacterial gene regulation
• Rahm Gummuluru, PhD
  Research interests: Molecular mechanisms of human immunodeficiency virus (HIV), dendritic cell interactions
• Andrew J. Henderson, PhD
  Research interests: Molecular events that regulate HIV expression
• Robin Ingalls, MD
  Research interests: Reproductive immunology and the pathogenesis of gonococcal and chlamydia infections
• Thomas Kepler, PhD
  Research interests: computational biology, systems biology, affinity maturation, humoral immunity, vaccine development
• Igor Kramnik, MD, PhD
  Research interests: innate immunity, genetics, host resistance, infection, tuberculosis, lung, interferon, macrophage
• Shinichiro Kurosawa, MD, PhD
  Research interests: Blood coagulation, thrombotic microangiopathy, Hemolytic Uremic Syndrome (HUS), endothelial biology, Disseminated Intravascular Coagulation (DIC), pre-clinical in vivo models, biodefense pathogens, infectious disease and sepsis
• Robert Lafyatis, MD
  Research interests: Fibrosis and autoimmunity in systemic sclerosis
• Adam Lerner, MD
  Research interests: Lymphoid malignancies and the role of focal-adhesion-associated proteins in breast cancer anti-estrogen resistance
• Joseph P. Mizgerd, ScD
  Research interests: Acute lower respiratory tract infection, cytokines, innate immunity, neutrophil recruitment and activation, pneumonia, transcriptional and post-transcriptional regulation of gene expression
• Gustavo Mostoslavsky, MD, PhD
  Research interests: Stem cell biology and gene therapy
• Elke Mühlberger, PhD
  Research interests: Host response to filovirus infection, molecular mechanisms of filovirus replication and transcription
• John R. Murphy, PhD
  Research interests: Structure of the diphtheria toxin repressor; diphtheria toxin catalytic domain and entry into the eukaryotic cell cytosol; structure- function of IL7
• Barbara S. Nikolajczyk, PhD
  Research interests: Inflammation in type 2 diabetes and other inflammatory diseases; molecular mechanisms of disease pathogenesis; regulation of IL-1 beta production
• Lee J. Quinton, PhD
  Research interests: Pulmonary host defense, innate immunity, acute lung injury, acute phase response
• Daniel G. Remick, MD
  Research interests: Sepsis, asthma, regulation of ongoing inflammation
• Ian Rifkin, MD, PhD
  Research interests: Mechanisms responsible for the pathogenesis of systemic lupus erythematosus and lupus-associated atherosclerosis
• Jennifer Schlezinger, PhD
  Research interests: Immunotoxicology, aryl hydrocarbon receptor and peroxisome proliferators activated receptor-g
• David C. Seldin, MD, PhD
  Research interests: Lymphoproliferative diseases and other malignancies; mechanisms of disease in the plasma cell disorder “systemic amyloidosis”
• Jacqueline Sharon, PhD
  Research interests: Generation and characterization of polyclonal antibody libraries for the treatment and diagnosis of cancer and infectious diseases
• David H. Sherr, PhD
  Research interests: Cancer immunotherapy; the role of the environmental chemical receptor (AhR) in regulatory T cell development; mechanisms of immunosuppression mediated by environmental pollutants; the role of the AhR in breast cancer
• Deborah J. Stearns-Kurosawa, PhD
  Research interests: Bacterial and toxin-induced pathogenesis models, vaccine and therapeutic interventions, endoplasmic reticulum stress responses
• Andrew Taylor, PhD
  Research interests: Immunprivilege in the eye; neuropeptides as inhibitors of immune responses; regulatory T cells
• Gregory A. Viglianti, PhD
  Research interests: Molecular biology of HIV-1; the role of virus-host cell interactions in pathogenesis
• Lee M. Wetzler, MD
  Research interests: Vaccine development; microbial immunity and pathogenesis; effect of bacterial products on eukaryotic cells
• Susan Winandy, PhD
  Research interests: Molecular immunology, development of the immune system, regulation of gene expression, cancer biology