Thomas Gilmore
Professor of Biology; Associate Director, Program in Molecular Biology, Cell Biology & Biochemistry
- Title Professor of Biology; Associate Director, Program in Molecular Biology, Cell Biology & Biochemistry
- Email gilmore@bu.edu
- Education A.B., Princeton University
Ph.D., University of California, Berkeley
Current research in the Gilmore laboratory focuses on the immunity and immune diseases. Much of our research focuses on the NF-kB transcription factor signaling pathway (www.nf-kb.org). In humans, we are studying how an overabundance of NF-kB activity can contribute to the growth and survival of B-cell lymphoma, and how reduced NF-kB activity (due to mutations in a signaling adapter protein NEMO) can contribute to immunodeficiency diseases. Finally, we are studying the evolution of NF-kB signaling and immunity in simple marine invertebrates and how NF-kB contributes to pathogen detection and the establishment and loss of symbiosis in environmentally threatened organisms such as sea anemones and corals. These projects involve collaborations with the labs of Karen Allen, John Porco, and Adrian Whitty in Chemistry, and Sarah Davies and John Finnerty in Biology.
- Research Areas
- Biochemistry, Biological Networks, Biomedical/Disease, Cancer Biology, Cell Biology, Developmental Biology, Ecology, Evolution, Host-microbe Interactions, Imaging, Immunology, Molecular Biology, Molecular Genetics & Genomics, Signal Transduction, and Transcriptional Regulation
- Affiliation
- Biology and Faculty