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iPSC Core Facility


Induced Pluripotent Stem Cells (iPSCs) generated by forced overexpression of defined transcription factors in somatic cells hold great promise for human disease research and personalized medicine. iPSCs show extensive self-renewal and have the ability to become any cell type in the body, providing an inexhaustible source of cells for in vitro disease modeling studies, screening of pharmacological compounds and regenerative therapies. The Center for Regenerative Medicine (CReM) iPSC Core was created to expedite the use of iPSC technology by providing essential services and support to on-campus investigators and the broader scientific community. To achieve this goal the CReM iPSC Core will:
  1. Generate and characterize iPSC lines from samples of adult tissues provided by the investigator.
    For more information visit Services.
  2. Serve as a repository for sharing control and disease-specific hiPSC lines with internal and external investigators to conduct both basic and translational research.
    For more information visit our CReM bank.
  3. Provide expertise, protocols and training to support work involving human iPSCs.


Marianne James, PhD
CReM iPSC Core manager
670 Albany Street, Room 251
Boston, MA 02118