{"id":266,"date":"2014-12-10T11:57:14","date_gmt":"2014-12-10T16:57:14","guid":{"rendered":"https:\/\/www.bu.edu\/zaman\/?post_type=profile&#038;p=266"},"modified":"2017-04-21T12:02:37","modified_gmt":"2017-04-21T16:02:37","slug":"alex-bloom","status":"publish","type":"profile","link":"https:\/\/www.bu.edu\/zaman\/profile\/alex-bloom\/","title":{"rendered":"Alex Bloom, Ph.D."},"content":{"rendered":"<h2><a href=\"https:\/\/www.bu.edu\/zaman\/files\/2014\/12\/AB-Resume-2014-updated.pdf\"><em>Curriculum Vitae<\/em><\/a><\/h2>\n<h2>Research Interests<span style=\"font-size: 1.5em;\"><\/span><\/h2>\n<p>During cancer cell metastasis from the primary tumor site, the extracellular matrix (ECM) is modified and reorganized by the cancer cells.\u00a0 My interests lies in understanding specifically how the ECM is modified to promote or allow for metastasis by using three dimensional tissue culture techniques<\/p>\n<h2>Selected Publications<\/h2>\n<p>Bloom, A. B. &amp; Zaman, M. H. (2014). Influence of the microenvironment on cell fate.\u00a0 <i>Physiological Genomics, 46, 309-314.<o:p><\/o:p><\/i><\/p>\n<p>Makkinje, A., Near, R. I., Infusini, G., Vanden Borre, P., Bloom, A., Cai, D., Costello, C., &amp; Lerner, A. (2009). AND-34\/BCAR3 regulates adhesion-dependent p130Cas serine phosphorylation and breast cancer cell growth pattern. <i>Cellular Signalling<\/i>, <i>21<\/i>(9), 1423\u20131435. <o:p><\/o:p><\/p>\n<p>Near, R. I., Smith, R. S., Toselli, P. A., Freddo, T. F., Bloom, A. B., Vanden Borre, P., Seldin, D., &amp; Lerner, A. (2009). Loss of AND-34\/BCAR3 expression in mice results in rupture of the adult lens. <i>Molecular Vision<\/i>, <i>15<\/i>, 685\u201399.<o:p><\/o:p><\/p>\n<p>Garron, M. L., Arsenieva, D., Zhong, J., Bloom, A. B., Lerner, A., O\u2019Neill, G. M., &amp; Arold, S. T. (2009). Structural insights into the association between BCAR3 and Cas family members, an atypical complex implicated in anti-oestrogen resistance.\u00a0<o:p><\/o:p><\/p>\n","protected":false},"author":7526,"template":"","_links":{"self":[{"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/profile\/266"}],"collection":[{"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/profile"}],"about":[{"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/types\/profile"}],"author":[{"embeddable":true,"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/users\/7526"}],"version-history":[{"count":7,"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/profile\/266\/revisions"}],"predecessor-version":[{"id":709,"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/profile\/266\/revisions\/709"}],"wp:attachment":[{"href":"https:\/\/www.bu.edu\/zaman\/wp-json\/wp\/v2\/media?parent=266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}